CN101066333A - Chinese medicine prepn for treating sterility of asthenospermia - Google Patents

Abstract

The present invention provides Chinese medicine preparation for treating sterility of asthenospermia. The Chinese medicine preparation is prepared with over ten kinds of Chinese medicinal materials, including deglued antler powder, morinda root, cheokee rose fruit, cassia, etc. It has the functions of warming kidney, strengthening yang, stopping emission and benefiting qi. The present invention is developed through combining syndrome analyzing treatment of Chinese medicine and modern research result. The Chinese medicine preparation has the features of determined curative effect, high safety, no toxic side effect and low cost.

Description

The Chinese medicine preparation of treatment low sperm activity infertility

Technical field

The present invention relates to treat the Chinese medicine preparation of low sperm activity infertility, is that the treatment low sperm activity infertility is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Low sperm activity, be meant 1～3 hour sperm in ejaculation back the motor capacity difference or completely without, the mobility classification is in the II level or below the II level; Or the 1st hour motile sperm rate less than 50%, the 6 hour motile sperm rate less than 10%.Low sperm activity is a major reason of male sterility.Primary disease belongs to the traditional Chinese medical science sick categories such as " seminal fluid being thin and colds ".Chinese medicine thinks, the generation of sperm and having or not is crucial in kidney essense, and the power of motility of sperm is crucial in kidney yang.So insufficiency of kidney-YANG, cold sperm is unable; Or because of damage of kidney-YIN, can not flourish supporting and cause low sperm activity; Or a little less than the empty blood of plain bromhidrosis, or, all can cause low sperm activity because of the smart chamber of retention of damp-heat in the interior, movable unable.The primary disease clinical manifestation finds not have obvious General Symptoms for how when sterile or semen efamination after marriage, if be secondary to after prostatitis, seminal vesiculitis, testis and the epididymis disease, can have corresponding symptom concurrently.Resembling of kidney yang deficiency of kidney-QI such as the visible sexual impotence of some patient, libido reduction, aversion to cold and cold limbs, fatigue and weakness, soreness of the waist and knees.Or see that urine is smooth, the heeltap not to the utmost, the resembling of retention of damp-heat in the interior such as oliguria with reddish urine, bitter taste in the mouth and dry throat.The traditional Chinese medical science is divided into insufficiency of kidney-YANG clinically, damage of kidney-YIN, and deficiency of qi and blood such as accumulates in warm at disease type Coryza Treated by Syndrome Differentiation, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the Chinese medicine preparation for the treatment of low sperm activity infertility.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.0～4 parts of 1.0～4 parts of Cortexs Eucommiae of 1.5～6 parts of Fructus Corni of Cornu Cervi Degelatinatum

1.0～4 parts of 1.0～4 parts of Radix Codonopsis of 1.5～6 parts of Fructus Lycii of Radix Morindae Officinalis

0.1～1 part of 1.0～4 parts of Radix Aconiti Lateralis Preparata of 1.5～6 parts of Cherokee roses of Herba Epimedii

0.1～2 part of 1.0～4 portions of Cortex Cinnamomi of 1.0～4 parts of Semen Cuscutae of Radix Rehmanniae Preparata

The weight proportion of each raw material of optimization formula of the present invention is:

1.5～2.5 parts of 1.5～2.5 parts of Cortexs Eucommiae of 2.5～3.5 parts of Fructus Corni of Cornu Cervi Degelatinatum

1.5～2.5 parts of 1.5～2.5 parts of Radix Codonopsis of 2.5～3.5 parts of Fructus Lycii of Radix Morindae Officinalis

0.3～0.7 part of 1.5～2.5 parts of Radix Aconiti Lateralis Preparata of 2.5～3.5 parts of Cherokee roses of Herba Epimedii

0.5～1.5 part of 1.5～2.5 portions of Cortex Cinnamomi of 1.5～2.5 parts of Semen Cuscutae of Radix Rehmanniae Preparata

The weight proportion of each raw material of optimum formula of the present invention is:

2 parts of 2 parts of Cortexs Eucommiae of 3 parts of Fructus Corni of Cornu Cervi Degelatinatum

2 parts of 2 parts of Radix Codonopsis of 3 parts of Fructus Lycii of Radix Morindae Officinalis

0.5 part of 2 parts of Radix Aconiti Lateralis Preparata of 3 parts of Cherokee roses of Herba Epimedii

1 part of 2 portions of Cortex Cinnamomi of 2 parts of Semen Cuscutae of Radix Rehmanniae Preparata

Drug action mechanism among the present invention is as follows:

The Cornu Cervi Degelatinatum property of medicine is salty, puckery, temperature.Return kidney, Liver Channel.Has reinforcing the kidney and supporting YANG, anastaltic effect.Can treat emission due to deficiency of the kidney, night sweat, anorexia and loose stool, chronic diarrhea chronic dysentery, metrorrhagia, leukorrhagia, frequent micturition, the enuresis, dribble of urine, skin infection disunion of a specified duration, wound hemorrhage etc.(the 3118th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Morindae Officinalis property of medicine suffering, sweet, tepor.Return liver, kidney channel.Has reinforcing the kidney and supporting YANG, bone and muscle strengthening, the effect of expelling wind and removing dampness.Can treat impotence due to deficiency of the kidney, the seminal emission premature ejaculation, few abdomen cold type of pain, incontinence of urine, cold womb is infertile, anemofrigid-damp arthralgia, soreness of the waist and knees, rheumatism beriberi etc.(the 709th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Herba Epimedii property of medicine suffering, sweet, temperature.Return kidney, Liver Channel.Has kidney invigorating and YANG supporting, strengthening the tendons and bones, the effect of expelling wind and removing dampness.Can treat impotence and seminal emission, cold caused by deficiency is sterile, the frequent micturition incontinence, and dyspnea and cough due to deficiency of the kidney, soreness of the waist and knees, rheumatic arthralgia, hemiplegia, extremity are meciless etc.(the 3152nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).

The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Rosae Laevigatae property of medicine acid, puckery, flat.Return spleen, kidney, urinary bladder channel.Has controlling nocturnal emission with astringent drugs, reducing urination, astringing intestine to stop diarrhea, the effect of leukorrhagia stopping.Can treat seminal emission, spermatorrhea, the enuresis, frequent micturition, chronic diarrhea, chronic dysentery, nebulousurine, leukorrhagia, metrorrhagia etc.(the 1976th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little suffering of the Cortex Eucommiae property of medicine, temperature.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect.Can treat soreness of waist and knee joint, sexual impotence, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion etc.(the 1514th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Aconiti Lateralis Preparata property of medicine suffering, sweet, heat, poisonous.GUIXIN, kidney, spleen channel.Has recuperating depleted YANG and rescuing the patient from collapse, the effect of dispelling cold and removing dampness.Can treat excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea is fainted contrary, trusted subordinate's cold type of pain, cold-dysentery, beriberi edema, anemofrigid-damp arthralgia, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses etc.(the 1672nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Cinnamomi property of medicine suffering, sweet, heat.Return kidney, spleen, the heart, Liver Channel.It is supporing yang to have the fire of benefit, dispersing cold for relieving pain, the effect of warming the meridian and promoting blood circulation.Can treat insufficiency of kidney-YANG, the aversion to cold and cold limbs of decline of the fire from the gate of life, soreness of the waist and knees, impotence and seminal emission, dysuria or frequency, the dyspnea with rapid and short breath of losing heart, all diseases of edema oliguria; Decline of the fire from the gate of life, fire is Gui Yuan not, floating YANG, refusing yang, and heat in the upper and cold in the lower, the flushed complexion cold foot, dizziness and tinnitus, dispute is rotten broken; Spleen-kidney vacuity cold, coldness and pain in the epigastrium, decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain; Cold womb is infertile, the dysmenorrhea amenorrhea, and the stasis of blood stagnated and suffered from abdominal pain puerperal; Carbuncle of yin nature multiple abscess, or deficiency and coldness carbuncle and ulcer difficulty in discharging of pus, or do not hold back after bursting etc.(the 1223rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Cornu Cervi Degelatinatum, Radix Morindae Officinalis and Herba Epimedii, is ministerial drug with Radix Rehmanniae Preparata, Fructus Corni, Fructus Lycii, Cherokee rose, Semen Cuscutae, the Cortex Eucommiae and Radix Codonopsis; With Radix Aconiti Lateralis Preparata and Cortex Cinnamomi is adjuvant.All medicines are harmonious, and are total to the tool warming the kidney to invigorate YANG, the effect of controlling nocturnal emission with astringent drugs QI invigorating.The treatment low sperm activity infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment low sperm activity infertility of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat low sperm activity infertility, prevention to low sperm activity infertility also has good effect, and the treatment low sperm activity infertility has determined curative effect, has no side effect, taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment low sperm activity infertility; Treatment low sperm activity infertility patient 20 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 50%, and 9 examples that take a turn for the better account for 45%, and more 1 example does not account for 5%, and total effective rate reaches 95%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

2 parts of 2 parts of Cortexs Eucommiae of 3 parts of Fructus Corni of Cornu Cervi Degelatinatum

2 parts of 2 parts of Radix Codonopsis of 3 parts of Fructus Lycii of Radix Morindae Officinalis

0.5 part of 2 parts of Radix Aconiti Lateralis Preparata of 3 parts of Cherokee roses of Herba Epimedii

1 part of 2 portions of Cortex Cinnamomi of 2 parts of Semen Cuscutae of Radix Rehmanniae Preparata

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment low sperm activity infertility that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, the Chinese medicine preparation of treatment low sperm activity infertility is characterized in that it is made by the following weight proportion raw material:

1.0～4 parts of 1.0～4 parts of Cortexs Eucommiae of 1.5～6 parts of Fructus Corni of Cornu Cervi Degelatinatum

1.0～4 parts of 1.0～4 parts of Radix Codonopsis of 1.5～6 parts of Fructus Lycii of Radix Morindae Officinalis

0.1～1 part of 1.0～4 parts of Radix Aconiti Lateralis Preparata of 1.5～6 parts of Cherokee roses of Herba Epimedii

0.1～2 part of 1.0～4 portions of Cortex Cinnamomi of 1.0～4 parts of Semen Cuscutae of Radix Rehmanniae Preparata.

2, the Chinese medicine preparation of treatment low sperm activity infertility according to claim 1, wherein the weight proportion of each raw material is:

1.5～2.5 parts of 1.5～2.5 parts of Cortexs Eucommiae of 2.5～3.5 parts of Fructus Corni of Cornu Cervi Degelatinatum

1.5～2.5 parts of 1.5～2.5 parts of Radix Codonopsis of 2.5～3.5 parts of Fructus Lycii of Radix Morindae Officinalis

0.3～0.7 part of 1.5～2.5 parts of Radix Aconiti Lateralis Preparata of 2.5～3.5 parts of Cherokee roses of Herba Epimedii

0.5～1.5 part of 1.5～2.5 portions of Cortex Cinnamomi of 1.5～2.5 parts of Semen Cuscutae of Radix Rehmanniae Preparata.

3, the Chinese medicine preparation of treatment low sperm activity infertility according to claim 1, wherein the weight proportion of each raw material is:

2 parts of 2 parts of Cortexs Eucommiae of 3 parts of Fructus Corni of Cornu Cervi Degelatinatum

2 parts of 2 parts of Radix Codonopsis of 3 parts of Fructus Lycii of Radix Morindae Officinalis

0.5 part of 2 parts of Radix Aconiti Lateralis Preparata of 3 parts of Cherokee roses of Herba Epimedii

1 part of 2 portions of Cortex Cinnamomi of 2 parts of Semen Cuscutae of Radix Rehmanniae Preparata.