CN103285285B - A kind of male sterility for the treatment of improves Chinese medicine of sperm survival rate and preparation method thereof - Google Patents
A kind of male sterility for the treatment of improves Chinese medicine of sperm survival rate and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of male sterility for the treatment of and improve Chinese medicine of sperm survival rate and preparation method thereof, first by Poria, Rhizoma Alismatis, Semen Plantaginis, Rhizoma Polygonati, Herba Cistanches, Radix Dipsaci, Radix Paeoniae Rubra, that Hirudo is ground into fine powder after concocting by above-mentioned weight proportion is for subsequent use, again Cortex Moutan, the Radix Rehmanniae, Radix Bupleuri, Radix Salviae Miltiorrhizae, Gypsum Fibrosum, Fructus Lycii, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Radix Glycyrrhizae, Fructus Forsythiae, Stigma Croci, Herba Houttuyniae, Rhizoma Smilacis Glabrae are decocted to concentrated solution by above-mentioned weight proportion, then by the fine powder of pulverizing and its mixing and stirring, grind after lyophilization as smalls makes powder.It has the effect of kidney-tonifying sperm-generating, promoting diuresis with drugs of tasteless flavour, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, especially be applicable to that mankind spermatozoon survival rate is low, seminal fluid not liquefaction, sperm concentration are low, azoospermia and prostatitis, varicocele, orchitis, seminal vesiculitis, Urinary system inflammation treatment, can make above symptom within the relatively short time, recover normal.
Description
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of andropathy and preparation method thereof, particularly relate to a kind of male sterility for the treatment of and improve Chinese medicine of sperm survival rate and preparation method thereof.
Background technology
Along with the development of society, the quickening of rhythm of life, there is a lot of irrational phenomenon in life and dietary structure, such as: edible oil deep-fried food, the food containing additive, the vegetable containing pesticide residues, sitting move less, take a bus instead of walking etc. causes the generation of some andropathys and infertility.Suffers from the Drug therapy that the low patient's great majority of infertility, sperm survival rate adopt kidney invigorating and YANG supporting, easily there is the side effect such as some mouthfeel dryness of the tongue, hyperactivity of fire caused by deficiency of YIN and inflammatory lesions in long kidney invigorating and YANG supporting, and these side effect can cause, and sperm survival rate is low, seminal fluid not liquefaction, sperm concentration are low, generation that is even azoospermia.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of safe without toxic side effect, can treat that mankind spermatozoon survival rate is low, seminal fluid not liquefaction, sperm concentration are low, the Chinese medicine of azoospermia.
Another technical problem to be solved by this invention is to provide a kind of method preparing said medicine.
Medicine of the present invention is the medicament be made up of the raw material of following weight proportioning:
Poria 15 ~ 75 Rhizoma Alismatis 15 ~ 75 Semen Plantaginis 12 ~ 60
Rhizoma Polygonati 15 ~ 75 Herba Cistanches 15 ~ 75 Radix Dipsaci 15 ~ 75
Radix Paeoniae Rubra 12 ~ 60 Hirudo 3 ~ 15 Cortex Moutan 12 ~ 60
The Radix Rehmanniae 20 ~ 100 Radix Bupleuri 12 ~ 60 Radix Salviae Miltiorrhizae 12 ~ 60
Gypsum Fibrosum 20 ~ 100 Fructus Lycii 15 ~ 75 Cortex Eucommiae 15 ~ 75
Radix Achyranthis Bidentatae 12 ~ 60 Radix Glycyrrhizae 10 ~ 50 Fructus Forsythiae 15 ~ 75
Stigma Croci 1 ~ 5 Herba Houttuyniae 20 ~ 100 Rhizoma Smilacis Glabrae 20 ~ 100.
And optimum proportioning of the present invention (weight portion) is:
Poria 45 Rhizoma Alismatis 45 Semen Plantaginis 36
Rhizoma Polygonati 45 Herba Cistanches 45 Radix Dipsaci 45
Radix Paeoniae Rubra 36 Hirudo 9 Cortex Moutan 36
The Radix Rehmanniae 60 Radix Bupleuri 36 Radix Salviae Miltiorrhizae 36
Gypsum Fibrosum 60 Fructus Lycii 45 Cortex Eucommiae 45
Radix Achyranthis Bidentatae 36 Radix Glycyrrhizae 30 Fructus Forsythiae 45
Stigma Croci 3 Herba Houttuyniae 60 Rhizoma Smilacis Glabrae 60.
The method preparing above-mentioned Chinese medicine is:
First Poria, Rhizoma Alismatis, Semen Plantaginis, Rhizoma Polygonati, Herba Cistanches, Radix Dipsaci, Radix Paeoniae Rubra, Hirudo are ground into fine powder after concocting by above-mentioned weight proportion, again Cortex Moutan, the Radix Rehmanniae, Radix Bupleuri, Radix Salviae Miltiorrhizae, Gypsum Fibrosum, Fructus Lycii, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Radix Glycyrrhizae, Fructus Forsythiae, Stigma Croci, Herba Houttuyniae, Rhizoma Smilacis Glabrae are decocted to concentrated solution by above-mentioned weight proportion, then by the fine powder of pulverizing and its mixing and stirring, grind after lyophilization as smalls makes powder.
Pharmacological effect: Poria; Promoting diuresis to eliminate damp pathogen, spleen invigorating invigorating middle warmer, mind tranquilizing and the heart calming; Rhizoma Alismatis: promoting diuresis to eliminate damp pathogen; Semen Plantaginis: clearing away heat and promoting diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving; Rhizoma Polygonati: invigorating the spleen and replenishing QI, nourishing YIN and moistening the lung; Herba Cistanches: kidney invigorating and YANG supporting, loosening bowel to relieve constipation; Radix Dipsaci: the liver and the kidney tonifying, activating collaterals to relieve pain, reuniting the fractured tendons and bones; Radix Paeoniae Rubra: promoting blood circulation and cooling blood, stasis-dispelling and pain-killing, liver heat removing and eyesight improving; Hirudo: removing blood stasis; Cortex Moutan: clearing away heat and cooling blood, activating blood circulation and dissipating blood stasis; The Radix Rehmanniae: heat clearing away YIN nourishing, relieving restlessness are calmed the nerves, reducing swelling and alleviating pain; Radix Bupleuri: evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy; Radix Salviae Miltiorrhizae: blood circulation promoting and blood stasis dispelling, relieving restlessness are calmed the nerves, reducing swelling and alleviating pain; Gypsum Fibrosum: resolving heat and reducing pathogenic fire, relieving restlessness quench the thirst; Fructus Lycii: nourishing the liver and kidney, nourishing the liver to improve visual acuity; The Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening; Radix Achyranthis Bidentatae: promoting blood circulation to restore menstrual flow, relaxing muscles and tendons profit numbness, conducting blood to flow downwards, inducing diuresis for treating stranguria syndrome; Radix Glycyrrhizae: spleen reinforcing lung moistening, relieving spasm to stop pain, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription; Fructus Forsythiae: heat-clearing and toxic substances removing, eliminating stagnation of relieving inflammation or internal heat; Stigma Croci: blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia; Herba Houttuyniae: heat-clearing and toxic substances removing, subduing inflammation, inducing diuresis for treating stranguria syndrome; Rhizoma Smilacis Glabrae: eliminating damp, detoxifying.
The present invention with Rhizoma Polygonati, Herba Cistanches, Radix Dipsaci, Fructus Lycii, the Cortex Eucommiae, Radix Rehmanniae enriching yin and nourishing kidney spermatogenesis for monarch, Poria, Rhizoma Alismatis, Semen Plantaginis, Rhizoma Smilacis Glabrae promoting diuresis with drugs of tasteless flavour are minister, assistant is with Cortex Moutan, Gypsum Fibrosum, Fructus Forsythiae, Herba Houttuyniae, Radix Bupleuri heat-clearing and toxic substances removing, make with Stigma Croci, Radix Paeoniae Rubra, Hirudo, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, Radix Glycyrrhizae and in, coordinating the actions of various ingredients in a prescription.Effect of kidney-tonifying sperm-generating, promoting diuresis with drugs of tasteless flavour, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling can be reached after said medicine synthesis, make that sperm survival rate is low, seminal fluid not liquefaction, sperm concentration are low recovers normal within the relatively short time.
The present invention is that mankind spermatozoon survival rate is low, seminal fluid not liquefaction, sperm concentration are low, treatment that is azoospermia provides one pure Chinese medicinal preparation safely and efficiently, good effect, and preparation is simple, and cost is low, has no obvious untoward reaction.
Detailed description of the invention
Embodiment one: the present embodiment is the medicament be made up of the raw material of following weight proportioning:
Poria 45 Rhizoma Alismatis 45 Semen Plantaginis 36
Rhizoma Polygonati 45 Herba Cistanches 45 Radix Dipsaci 45
Radix Paeoniae Rubra 36 Hirudo 9 Cortex Moutan 36
The Radix Rehmanniae 60 Radix Bupleuri 36 Radix Salviae Miltiorrhizae 36
Gypsum Fibrosum 60 Fructus Lycii 45 Cortex Eucommiae 45
Radix Achyranthis Bidentatae 36 Radix Glycyrrhizae 30 Fructus Forsythiae 45
Stigma Croci 3 Herba Houttuyniae 60 Rhizoma Smilacis Glabrae 60.
By the preparation method that above-mentioned each component makes medicine of the present invention be:
First by Poria, Rhizoma Alismatis, Semen Plantaginis, Rhizoma Polygonati, Herba Cistanches, Radix Dipsaci, Radix Paeoniae Rubra, that Hirudo is ground into fine powder after concocting by above-mentioned weight proportion is for subsequent use, again Cortex Moutan, the Radix Rehmanniae, Radix Bupleuri, Radix Salviae Miltiorrhizae, Gypsum Fibrosum, Fructus Lycii, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Radix Glycyrrhizae, Fructus Forsythiae, Stigma Croci, Herba Houttuyniae, Rhizoma Smilacis Glabrae are changed after being fried boiling with intense fire by above-mentioned weight proportion with 30 minutes at a simmer, leach medicinal liquid, the medicinal liquid reconcentration obtained is become concentrated solution, then by the fine powder of pulverizing and its mixing and stirring, grind after lyophilization as smalls makes powder.Each 8-10 gram, every day three times, boiled water is taken after mixing it with water after meal.Within 30 days, be a course for the treatment of, the lighter 1-2 can fully recover a course for the treatment of, and severe one 3-5 the course for the treatment of can fully recover.
By modernization of Chinese medicine technology, above-mentioned weight proportion is made the dosage forms such as capsule, tablet, pill, granule, oral liquid, the customary adjuvant required for also can adding when preparing different dosage form.The present invention is except treatment mankind spermatozoon survival rate is low, seminal fluid not liquefaction, sperm concentration are low, azoospermia, can also treat prostatitis, varicocele, orchitis, seminal vesiculitis and Urinary system inflammation.
Embodiment two: the present embodiment is the medicament be made up of the raw material of following weight proportioning:
Poria 15 Rhizoma Alismatis 15 Semen Plantaginis 12
Rhizoma Polygonati 15 Herba Cistanches 15 Radix Dipsaci 15
Radix Paeoniae Rubra 12 Hirudo 3 Cortex Moutan 12
The Radix Rehmanniae 20 Radix Bupleuri 12 Radix Salviae Miltiorrhizae 12
Gypsum Fibrosum 20 Fructus Lycii 15 Cortex Eucommiae 15
Radix Achyranthis Bidentatae 12 Radix Glycyrrhizae 10 Fructus Forsythiae 15
Stigma Croci 1 Herba Houttuyniae 20 Rhizoma Smilacis Glabrae 20.
Above-mentioned each component makes the preparation method of medicine of the present invention and embodiment one in like manner can obtain.
Embodiment three: the present embodiment is the medicament be made up of the raw material of following weight proportioning:
Poria 75 Rhizoma Alismatis 75 Semen Plantaginis 60
Rhizoma Polygonati 75 Herba Cistanches 75 Radix Dipsaci 75
Radix Paeoniae Rubra 60 Hirudo 15 Cortex Moutan 60
The Radix Rehmanniae 100 Radix Bupleuri 60 Radix Salviae Miltiorrhizae 60
Gypsum Fibrosum 100 Fructus Lycii 75 Cortex Eucommiae 75
Radix Achyranthis Bidentatae 60 Radix Glycyrrhizae 50 Fructus Forsythiae 75
Stigma Croci 5 Herba Houttuyniae 100 Rhizoma Smilacis Glabrae 100.
Above-mentioned each component makes the preparation method of medicine of the present invention and embodiment one in like manner can obtain.
Observation of curative effect: the present invention 30 days is a course for the treatment of, and the lighter 1-2 can fully recover a course for the treatment of, and severe one 3-5 the course for the treatment of can fully recover.Observe through a large amount of clinical practice, truly have the effect of kidney-tonifying sperm-generating, promoting diuresis with drugs of tasteless flavour, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, be especially applicable to that mankind spermatozoon survival rate is low, seminal fluid not liquefaction, sperm concentration are low, azoospermia and prostatitis, varicocele, orchitis, seminal vesiculitis, Urinary system inflammation treatment.
Type case one:
Xu XX, man, 28 years old, main suit: marry not educate for 3 years and drip white 2 years with frequent micturition.
Patient occurs that frequent micturition drips white symptom after marrying before 3 years, and sexual life is normal, within 3 years, does not give birth to.Going to a doctor when the People's Hospital of districts and cities in 2009, checking Semen routione: sperm survival rate does not liquefy for 36%, 30 minutes, sperm concentration is low, leukocyte ++, be diagnosed as infertility, chronic prostatitis.Through taking antibiotic medicine and kidney invigorating and YANG supporting class Chinese patent medicine February invalidly comes to go to a doctor.Examine and see that tongue fur is white thick slightly yellow, rapid pulse.Chinese medical discrimination is retention of damp-heat in the interior, mutually fiery high Sheng causes seminal fluid not liquefy completely, and give this preparation one course for the treatment of, taking rear review result is: sperm survival rate 59%, and within 30 minutes, liquefy completely, density is normal.Give again a course of therapy, review result: sperm survival rate 76%, sundry item is completely normal, and chronic prostatitis syndrome shape disappears, and has followed up a case by regular visits to a boy after 1 year.
Typical case two:
Zhao XX, man, 29 years old, main suit: marry and do not educate for 4 years with dampness of scrotum, distending pain of the testis 2 years.
Patient married before 4 years, and sexual life is normal, within 4 years, did not give birth to and with dampness of scrotum, distending pain of the testis 2 years, continued to increase the weight of 15 days, be diagnosed as infertility, varicocele in 2008 in local county people's hospital.Check Semen routione: sperm survival rate 11%, sperm concentration are low, pH value is low, vigor is poor, invalidly come to go to a doctor through therapy of combining Chinese and Western medicine half a year.Examine and see that yellow fur is thick, hesitant pulse is number slightly.Chinese medical discrimination is: qi depression to blood stasis, retention of damp-heat in the interior, mutually fiery high Sheng cause sperm survival rate low, and give this preparation one course for the treatment of, taking rear review result is: sperm survival rate 23%.Give again a course of therapy, review result is: sperm survival rate 45%, and Varicocele shape alleviates, continue to give a course of therapy, review result is: sperm survival rate 73%, density and pH value normal, vigor is normal, and dampness of scrotum, distending pain of the testis, Varicocele shape all disappear.A raw healthy boy is followed up a case by regular visits to after 1 year.
Claims (3)
1. treat the Chinese medicine that male sterility improves sperm survival rate, it is characterized in that: it is the medicament be made up of the raw material of following weight proportioning:
Poria 15 ~ 75 Rhizoma Alismatis 15 ~ 75 Semen Plantaginis 12 ~ 60
Rhizoma Polygonati 15 ~ 75 Herba Cistanches 15 ~ 75 Radix Dipsaci 15 ~ 75
Radix Paeoniae Rubra 12 ~ 60 Hirudo 3 ~ 15 Cortex Moutan 12 ~ 60
The Radix Rehmanniae 20 ~ 100 Radix Bupleuri 12 ~ 60 Radix Salviae Miltiorrhizae 12 ~ 60
Gypsum Fibrosum 20 ~ 100 Fructus Lycii 15 ~ 75 Cortex Eucommiae 15 ~ 75
Radix Achyranthis Bidentatae 12 ~ 60 Radix Glycyrrhizae 10 ~ 50 Fructus Forsythiae 15 ~ 75
Stigma Croci 1 ~ 5 Herba Houttuyniae 20 ~ 100 Rhizoma Smilacis Glabrae 20 ~ 100.
2. treatment male sterility according to claim 1 improves the Chinese medicine of sperm survival rate, it is characterized in that: wherein the weight proportion of each raw material is:
Poria 45 Rhizoma Alismatis 45 Semen Plantaginis 36
Rhizoma Polygonati 45 Herba Cistanches 45 Radix Dipsaci 45
Radix Paeoniae Rubra 36 Hirudo 9 Cortex Moutan 36
The Radix Rehmanniae 60 Radix Bupleuri 36 Radix Salviae Miltiorrhizae 36
Gypsum Fibrosum 60 Fructus Lycii 45 Cortex Eucommiae 45
Radix Achyranthis Bidentatae 36 Radix Glycyrrhizae 30 Fructus Forsythiae 45
Stigma Croci 3 Herba Houttuyniae 60 Rhizoma Smilacis Glabrae 60.
3. the treatment male sterility that one of claim 1-2 is described improves the preparation method of the Chinese medicine of sperm survival rate, it is characterized in that: first by Poria, Rhizoma Alismatis, Semen Plantaginis, Rhizoma Polygonati, Herba Cistanches, Radix Dipsaci, Radix Paeoniae Rubra, Hirudo is ground into fine powder after concocting by above-mentioned weight proportion, again by Cortex Moutan, the Radix Rehmanniae, Radix Bupleuri, Radix Salviae Miltiorrhizae, Gypsum Fibrosum, Fructus Lycii, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Radix Glycyrrhizae, Fructus Forsythiae, Stigma Croci, Herba Houttuyniae, Rhizoma Smilacis Glabrae is decocted to concentrated solution by above-mentioned weight proportion, then by the fine powder of pulverizing and its mixing and stirring, grind after lyophilization as smalls makes powder.
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| CN105031252A (en) * | 2015-06-30 | 2015-11-11 | 虞志秋 | Traditional Chinese medicinal capsules for treating acute testitis |
| CN105031251A (en) * | 2015-06-30 | 2015-11-11 | 虞志秋 | Traditional Chinese medicinal decoction for treating acute testitis |
| CN114377077A (en) * | 2022-01-05 | 2022-04-22 | 广西雄邦医药科技有限公司 | Traditional Chinese medicine for tonifying five internal organs, strengthening muscles and bones, producing sperm and increasing sperm in testis and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1814251A (en) * | 2005-04-28 | 2006-08-09 | 陈宏棕 | Chinese medicine preparation for treating male sterility |
| CN101066405A (en) * | 2007-06-05 | 2007-11-07 | 北京艺信堂医药研究所 | Chinese medicine composition for treating sterility of aspermia |
| CN101195015A (en) * | 2007-11-30 | 2008-06-11 | 黄宁芝 | Chinese medicine for treating barrenness |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1814251A (en) * | 2005-04-28 | 2006-08-09 | 陈宏棕 | Chinese medicine preparation for treating male sterility |
| CN101066405A (en) * | 2007-06-05 | 2007-11-07 | 北京艺信堂医药研究所 | Chinese medicine composition for treating sterility of aspermia |
| CN101195015A (en) * | 2007-11-30 | 2008-06-11 | 黄宁芝 | Chinese medicine for treating barrenness |
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