CN101095820A - Chinese medicine preparation for treating diabetes - Google Patents

Abstract

The invention relates to a Chinese medicament for treating diabetes which is prepared from more than ten kinds of Chinese medicinal herbs including dried rehmannia root, cornus officinalis, Chinese yam and bark of peony root. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

A kind of Chinese medicine preparation of treatment diabetes

Technical field

The present invention relates to treat a kind of Chinese medicine preparation of diabetes, is that a kind of diabetes for the treatment of are the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Diabetes are ancient disease, and just there is being certain understanding in many countries between east and west to it a long time ago.Now, one of the cardiovascular and cerebrovascular disease that continues, tumor subsequent great epidemic diseases have been become more.Because the seriousness of its complication has caused global medical science circle and World Health Organization (WHO) and the public's serious concern.Chinese Medicine scholar has rich experience to diabetes control.Tradition doctor's nationality all carries the theory and the therapy of having recorded this respect as " interior warp ", " Medical Treasures of the Golden Chamber ", " prescriptions worth thousand gold " and " medical secrets of official-" etc.; Belong to sick category such as " quenching one's thirst ", " diseases due to endogenous heat of ZANG FU organs " substantially.7th century of the Christian era Zhen Quan of Tang work " recording proved recipe at all times ", 50 volumes have been narrated primary disease " thirsty and drinking a lot of water, frequent micturition, no fat be bran flakes seemingly, sweet person, all diabetes also ".Diabetes are a kind of common incretion metabolism diseases.According to WHO prediction, 21 century diabetes will be popular in developing country, will be to world diabetes patient in 2005 above 200,000,000.The present non-insulin-dependent diabetes mellitus prevalence of China is 3.22%, the impaired glucose tolerance person reaches 4.72%, and the diabetes annual morbidity is 1,30/,100,000, increases by 3 times in nearly 5 years, China suffers from the diabetes number at present and surpasses 3,500 ten thousand, the edge crowd who still has fifty-five million not made a definite diagnosis.China's new trouble diabetes number every year, every day, diabetes became the heavy burden of society and household economy with 3500 people's speed increase with 1,250,000, and the study on prevention of actively developing diabetes is an important topic in China's sanitary work.The traditional Chinese medical science is divided clinically and disease type Coryza Treated by Syndrome Differentiation such as is stopped in dryness-heat being excessive in the interior, deficiency of both QI and YIN, stagnation of QI and blood, deficiency of both YIN and YANG, damp-heat gluing each other, the pathogenic water, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetes.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.5～6 parts in 1.5～6 portions of Fructus Moris of 1.5～6 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

1.0～4 parts of 1.0～4 portions of Rhizoma Dioscoreaes of 1.0～4 parts of Cortex Moutans of Fructus Corni

1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.0～4 portions of Cortex Phellodendris of Radix Cyathulae

0.1～2 part of 0.1～2 portion of Rhizoma Coptidis of 0.1～2 part of Radix Trichosanthis of Semen Plantaginis.

The weight proportion of each raw material of optimization formula of the present invention is:

2.5～3.5 parts in 2.5～3.5 portions of Fructus Moris of 2.5～3.5 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Dioscoreaes of 1.5～2.5 parts of Cortex Moutans of Fructus Corni

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 1.5～2.5 portions of Cortex Phellodendris of Radix Cyathulae

0.5～1.5 part of 0.5～1.5 portion of Rhizoma Coptidis of 0.5～1.5 part of Radix Trichosanthis of Semen Plantaginis.

The weight proportion of each raw material of optimum formula of the present invention is:

3 parts in 3 portions of Fructus Moris of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

2 parts of 2 portions of Rhizoma Dioscoreaes of 2 parts of Cortex Moutans of Fructus Corni

2 parts of 2 portions of Rhizoma Alismatis of 2 portions of Cortex Phellodendris of Radix Cyathulae

1 part of 1 portion of Rhizoma Coptidis of 1 part of Radix Trichosanthis of Semen Plantaginis.

Drug action mechanism among the present invention is as follows:

The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).

Rhizoma Anemarrhenae property of medicine hardship, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, nourishing yin and moistening dryness.Can treat epidemic febrile disease hyperpyrexia excessive thirst, the cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia is quenched one's thirst etc.(the 1924th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Mori property of medicine is sweet, sour, and is cold.Return liver, kidney channel.Have nourishing YIN and benefiting blood, promote the production of body fluid, the effect of intestine moistening.Can treat having a dizzy spell of deficiency of the liver and kindey and blood deficiency damage of essence, tinnitus, early whitening of beard and hair, the soreness of waist, dryness of the intestine constipation, tinea alba etc. are quenched one's thirst in insomnia.(the 2791st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever ， Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Trichosanthis property of medicine is slightly cold.Attach to the lung and stomach meridians.Has clearing away heat and promoting production of body fluid, moistening the lung and resolving phlegm, the effect of detumescence and apocenosis.It is thirsty to treat calentura, the polydipsia of quenching one's thirst, lung-heat type cough, sore swollen toxin etc.(the 443rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Coptidis nature and flavor hardship, cold.GUIXIN, liver, stomach, large intestine channel.Has clearing away heat-fire, dampness, antidotal effect.Cure mainly the calentura heresy and go into the hyperpyrexia of heart channel, agitation, delirium or the absurd row of intenseness of heat forcing blood tell nosebleed, the damp and hot feeling of stuffiness in chest is had loose bowels, dysentery, the vexed insomnia of hyperactivity of heart-fire, gastropyretic vomiting, rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain, and pathopyretic ulcer, the furunculosis septicemia, gingival swelling and pain, aphtha of the mouth and tongue, hemorrhoidal bleeding, eczema is scalded etc.(the 2818th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae, the Rhizoma Anemarrhenae, Fructus Mori and Radix Trichosanthis; With Fructus Corni, Cortex Moutan, Rhizoma Dioscoreae, Radix Cyathulae, Cortex Phellodendri and Rhizoma Alismatis is ministerial drug; With Semen Plantaginis and Rhizoma Coptidis is adjuvant.All medicines are harmonious, and are total to the tool nourishing YIN to lower pathogenic fire, the effect of liver and kidney tonifying.The treatment diabetes have determined curative effect, have no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetes of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat diabetes, and the prevention of diabetes is also had good effect, and the treatment diabetes have determined curative effect, have no side effect taking convenience, cheap characteristics.

For showing medicine of the present invention, as follows through clinical test results to treatment treatment of diabetes effect; Treatment diabetics 25 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.13 examples of fully recovering account for 52%, and 9 examples that take a turn for the better account for 36%, and invalid 3 examples account for 12%, and total effective rate reaches 88%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

3 parts in 3 portions of Fructus Moris of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

2 parts of 2 portions of Rhizoma Dioscoreaes of 2 parts of Cortex Moutans of Fructus Corni

2 parts of 2 portions of Rhizoma Alismatis of 2 portions of Cortex Phellodendris of Radix Cyathulae

1 part of 1 portion of Rhizoma Coptidis of 1 part of Radix Trichosanthis of Semen Plantaginis.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetes that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine preparation of treatment diabetes is characterized in that it is made by the following weight proportion raw material:

1.5～6 parts in 1.5～6 portions of Fructus Moris of 1.5～6 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

1.0～4 parts of 1.0～4 portions of Rhizoma Dioscoreaes of 1.0～4 parts of Cortex Moutans of Fructus Corni

1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.0～4 portions of Cortex Phellodendris of Radix Cyathulae

0.1～2 part of 0.1～2 portion of Rhizoma Coptidis of 0.1～2 part of Radix Trichosanthis of Semen Plantaginis.

2, a kind of Chinese medicine preparation of treatment diabetes according to claim 1, wherein the weight proportion of each raw material is:

2.5～3.5 parts in 2.5～3.5 portions of Fructus Moris of 2.5～3.5 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Dioscoreaes of 1.5～2.5 parts of Cortex Moutans of Fructus Corni

1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 1.5～2.5 portions of Cortex Phellodendris of Radix Cyathulae

0.5～1.5 part of 0.5～1.5 portion of Rhizoma Coptidis of 0.5～1.5 part of Radix Trichosanthis of Semen Plantaginis.

3, a kind of Chinese medicine preparation of treatment diabetes according to claim 1, wherein the weight proportion of each raw material is:

3 parts in 3 portions of Fructus Moris of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae

2 parts of 2 portions of Rhizoma Dioscoreaes of 2 parts of Cortex Moutans of Fructus Corni

2 parts of 2 portions of Rhizoma Alismatis of 2 portions of Cortex Phellodendris of Radix Cyathulae

1 part of 1 portion of Rhizoma Coptidis of 1 part of Radix Trichosanthis of Semen Plantaginis.