CN101095775A - Chinese traditional medicine for treating diabetes deafness - Google Patents

Abstract

The invention relates to a Chinese medicament for treating diabetic deafness, which is prepared from more than ten kinds of Chinese medicinal herbs including Bupleurum root, peach kernels, kudzu root and sweetgum fruit. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

A kind of Chinese medicine of treatment diabetic deafness

Technical field

The present invention relates to treat a kind of Chinese patent medicine of diabetic deafness, is that a kind of diabetic deafness for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Hypoacusis is so that the appearance deafness is one of common chronic complicating diseases of diabetics.Report early than Jordao discovery diabetics dysaudia in 1857 studies have shown that in a large number that afterwards the incidence rate of diabetes dysaudia reaches 35%～55%.Mainly betide the gerontal patient, Gibbin carries out research more than 2 years to the diabetics more than 50 years old and non-diabetic person of the same age, and the result shows that the diabetics threshold of audibility is significantly higher than matched group, and the auditory dysesthesia rate is 48%, and matched group is 10%.Diabetes dysacousis is equivalent to the Hiccough and deaf disease of the traditional Chinese medical science, and deafness claims deafness again.Sui Dynasty " all source of disease marquis's opinions " has been done the record than detail to tinnitus, deaf etiology and pathogenesis, thinks due to " impairment caused by overstrain is in kidney, and assembled channels is deficient, the vim and vigour deficiency "." element is asked the logical deficiency and excess opinion of commenting ": " institute of the intestines and stomach gives birth to also for headache tinnitus, dysfunction of the nine orifices ", " taste were both taken advantage of by YIN-fire, and essence derived from food is inaccessible and dirty, i.e. clear QI failing to ascend, nine orifices is unfavorable for it ", the not normal pathomechanism that causes tinnitus, deafness of spleen and stomach function is described." Elementary Medicine ": " deafness has the difference of expectorant, fire, wind, wet, gas-tight, gas labor loss of essence." with the passing of time the deaf big reason deficiency of YIN of diabetes cause, most based on deficiency syndrome.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as deficiency of kidney-essence, kidney yang deficiency, disarmony between the heart and kidney clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetic deafness.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

0.1～2 part on 1.0～4 parts of Flos Carthamis of 1.5～6 parts of Fructus Aurantii Immaturuss of Radix Salviae Miltiorrhizae

0.1～2 part of 1.0～4 parts of Fructus Liquidambaris of 1.5～6 parts of Radix Puerariaes of Concha Ostreae

0.1～2 part of 1.0～4 parts of Fructus Corni of 1.0～4 parts of Semen Persicaes of Radix Bupleuri

0.1～2 part of 0.1～2 part of Radix Glycyrrhizae of 0.1～2 part of Rhizoma Chuanxiong of Rhizoma Acori Graminei.

The weight proportion of each raw material of optimization formula of the present invention is:

0.5～1.5 part on 1.5～2.5 parts of Flos Carthamis of 2.5～3.5 parts of Fructus Aurantii Immaturuss of Radix Salviae Miltiorrhizae

0.5～1.5 part of 1.5～2.5 parts of Fructus Liquidambaris of 2.5～3.5 parts of Radix Puerariaes of Concha Ostreae

0.5～1.5 part of 1.5～2.5 parts of Fructus Corni of 1.5～2.5 parts of Semen Persicaes of Radix Bupleuri

0.5～1.5 part of 0.5～1.5 part of Radix Glycyrrhizae of 0.5～1.5 part of Rhizoma Chuanxiong of Rhizoma Acori Graminei.

The weight proportion of each raw material of optimum formula of the present invention is:

1 part on 2 parts of Flos Carthamis of 3 parts of Fructus Aurantii Immaturuss of Radix Salviae Miltiorrhizae

1 part of 2 parts of Fructus Liquidambaris of 3 parts of Radix Puerariaes of Concha Ostreae

1 part of 2 parts of Fructus Corni of 2 parts of Semen Persicaes of Radix Bupleuri

1 part of 1 part of Radix Glycyrrhizae of 1 part of Rhizoma Chuanxiong of Rhizoma Acori Graminei.

Drug action mechanism among the present invention is as follows:

Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Concha Ostreae property of medicine is salty, is slightly cold.Return liver, kidney channel.Have suppressing the hyperactive liver and subsiding YANG, tranquillization with heavy prescription, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating effect.Can treat vertigo and tinnitus, palpitation with fear insomnia, scrofula goiter ， mass in the abdomen mass in the abdomen, spontaneous sweating, seminal emission, metrorrhagia, leukorrhagia etc.(the 1574th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).

Fructus Aurantii Immaturus property of medicine hardship, suffering are slightly cold.Return spleen, stomach, large intestine channel.Have the dispelling the stagnated QI removing food stagnancy, reduce phlegm except that the effect of painful abdominal mass.Can treat and stop in stagnant, the feeling of fullness distending pain, constipation, heavy behind the dysentery, blocked-up chest, the thoracic obstruction, gastroptosis, uterine prolapse, proctoptosis etc.(the 2231st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Puerariae nature and flavor are sweet, hot, cold.Return spleen, stomach warp.Have expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash, yang invigorating antidiarrheal effect.Have fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea is had loose bowels; Hypertension neck pain etc.(the 274th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

Semen Persicae property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Flos Carthami property of medicine suffering, temperature.GUIXIN, Liver Channel.Has promoting blood circulation to restore menstrual flow, the effect of stasis-dispelling and pain-killing.Can treat the blood stasis amenorrhea, dysmenorrhea, postpartum stagnation stomachache, obstruction of qi in the chest and cardialgia ， mass in the abdomen knot is poly-, traumatic injury, arthralgia, apoplectic hemiplegia, macule etc.(the 2763rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Liquidambaris property of medicine hardship, flat.Return liver, urinary bladder channel.Has dispelling, collateral-activating, the effect of diuretic dehumidifying.Can treat rheumatic arthralgia, wither muscle knot of limb, epigastric pain, amenorrhea, galactostasis, edema, eczema etc.(the 3470th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Acori Graminei property of medicine suffering, hardship, tepor.GUIXIN, liver, spleen channel.Have and eliminate phlegm for resuscitation, removing dampness to restore normal function of the stomach, the effect of mind calming benefit will.Can treat the calentura coma, syncope due to accumulation of phlegm, forgetful, insomnia, tinnitus, deafness, fasting dysentery, rheumatic arthralgia etc.(the 854th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Glycyrrhizae property of medicine is sweet, and is flat.Return spleen, stomach, the heart, lung meridian.Have and middle emergency lung moistening, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription.Can treat weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough; Give birth to controlling laryngopharynx swelling and pain, the carbuncle pyogenic infections from tumour or sore, infantile carbuncle reaches medicine, alimentary toxicosis etc.(the 792nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Rhizoma Acori Graminei and Concha Ostreae; With Radix Bupleuri, Semen Persicae, Fructus Aurantii Immaturus, Radix Puerariae and Flos Carthami is ministerial drug; With Fructus Liquidambaris, Fructus Corni and Radix Glycyrrhizae is adjuvant.All medicines are harmonious, and are total to the tool blood circulation promoting and blood stasis dispelling, the effect that circulation of qi promoting is sensible.The treatment diabetic deafness has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetic deafness of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat diabetic deafness, and the prevention of diabetic deafness is also had good effect, and the treatment diabetic deafness has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic deafness; Treatment diabetic deafness patient 22 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.11 examples of fully recovering account for 50%, and 9 examples that take a turn for the better account for 40.91%, and invalid 2 examples account for 9.09%, and total effective rate reaches 90.91%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

1 part on 2 parts of Flos Carthamis of 3 parts of Fructus Aurantii Immaturuss of Radix Salviae Miltiorrhizae

1 part of 2 parts of Fructus Liquidambaris of 3 parts of Radix Puerariaes of Concha Ostreae

1 part of 2 parts of Fructus Corni of 2 parts of Semen Persicaes of Radix Bupleuri

1 part of 1 part of Radix Glycyrrhizae of 1 part of Rhizoma Chuanxiong of Rhizoma Acori Graminei.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic deafness that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine of treatment diabetic deafness is characterized in that it is made by the following weight proportion raw material:

0.1～2 part on 1.0～4 parts of Flos Carthamis of 1.5～6 parts of Fructus Aurantii Immaturuss of Radix Salviae Miltiorrhizae

0.1～2 part of 1.0～4 parts of Fructus Liquidambaris of 1.5～6 parts of Radix Puerariaes of Concha Ostreae

0.1～2 part of 1.0～4 parts of Fructus Corni of 1.0～4 parts of Semen Persicaes of Radix Bupleuri

0.1～2 part of 0.1～2 part of Radix Glycyrrhizae of 0.1～2 part of Rhizoma Chuanxiong of Rhizoma Acori Graminei.

2, a kind of Chinese medicine of treatment diabetic deafness according to claim 1, wherein the weight proportion of each raw material is:

0.5～1.5 part on 1.5～2.5 parts of Flos Carthamis of 2.5～3.5 parts of Fructus Aurantii Immaturuss of Radix Salviae Miltiorrhizae

0.5～1.5 part of 1.5～2.5 parts of Fructus Liquidambaris of 2.5～3.5 parts of Radix Puerariaes of Concha Ostreae

0.5～1.5 part of 1.5～2.5 parts of Fructus Corni of 1.5～2.5 parts of Semen Persicaes of Radix Bupleuri

0.5～1.5 part of 0.5～1.5 part of Radix Glycyrrhizae of 0.5～1.5 part of Rhizoma Chuanxiong of Rhizoma Acori Graminei.

3, a kind of Chinese medicine of treatment diabetic deafness according to claim 1, wherein the weight proportion of each raw material is:

1 part on 2 parts of Flos Carthamis of 3 parts of Fructus Aurantii Immaturuss of Radix Salviae Miltiorrhizae

1 part of 2 parts of Fructus Liquidambaris of 3 parts of Radix Puerariaes of Concha Ostreae

1 part of 2 parts of Fructus Corni of 2 parts of Semen Persicaes of Radix Bupleuri

1 part of 1 part of Radix Glycyrrhizae of 1 part of Rhizoma Chuanxiong of Rhizoma Acori Graminei.