CN103349774B - Drug for treating diabetes mellitus - Google Patents

Abstract

The invention discloses a drug for treating diabetes mellitus. The drug is prepared by the following raw materials in parts by weight: 20-100 parts of red ginseng, 100-250 parts of astragalus mongholicus, 15-30 parts of bighead atractylodes rhizome, 15-30 parts of poria cocos, 15-30 parts of fructus amomi, 15-30 parts of ginger processed pinellia, 30-60 parts of reddish orange, 30-50 parts of rhizoma zingiberis, 15-20 parts of peach kernel, 15-30 parts of carthamus tinctorius, 30-60 parts of white mustard seeds, 20-50 parts of fructus alpiniae oxyphyllae, 20-50 parts of radix linderae, 30-100 parts of rhizoma drynariae, and 15-30 parts of hard clam. The drug is strict in compatibility, dialectical, and appropriate in prescription, acts appropriately to the situation, allows the diabetes mellitus to recur difficultly after the diabetes mellitus is cured, allows complications to disappear, and allows blood sugar and urine sugar to return to normal.

Description

The medicine for the treatment of diabetes

Technical field

The invention belongs to the field of Chinese medicines, relate to a kind of medicine for the treatment of diabetes.

Technical background

The diabetes of doctor trained in Western medicine, high with blood glucose, have glucose in urine, three high and one low for diagnostic point, point two types.One is insulin-dependent, and two is kidney (kidney Distal convoluted tubule, proximal convoluted tubule are lost the absorption function of sugar, and pathomechanism is failed to understand).

Current treatment diabetes all moisturizing are main (hyperactivity of fire caused by deficiency of YIN), therefore the curative effect of medicine not obvious.

summary of the invention:

The object of this invention is to provide a kind of medicine for the treatment of diabetes.

The medicine that the present invention treats diabetes is made up of the raw material of following weight parts proportioning:

Radix Ginseng Rubra 20-100 parts, the Radix Astragali 100-250 parts, the Rhizoma Atractylodis Macrocephalae 15-30 parts, 15-30 parts, Poria, Fructus Amomi 15-30 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15-30 parts, Exocarpium Citri Rubrum 30-60 parts, Rhizoma Zingiberis 30-50 parts, 15-20 parts, Semen Persicae, 15-30 parts, Flos Carthami, Semen Sinapis Albae 30-60 parts, Fructus Alpiniae Oxyphyllae 20-50 parts, the Radix Linderae 20-50 parts, Rhizoma Drynariae 30-100 parts, Conch Meretricis seu Cyclinae 15-30 parts.

Preferred weight part proportioning that the present invention treats the medicine of diabetes is:

Radix Ginseng Rubra 80 parts, the Radix Astragali 160 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, 30 parts, Poria, Fructus Amomi 15 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20 parts, Exocarpium Citri Rubrum 30 parts, Rhizoma Zingiberis 30 parts, 15 parts, Semen Persicae, 30 parts, Flos Carthami, Semen Sinapis Albae 30 parts, Fructus Alpiniae Oxyphyllae 30 parts, the Radix Linderae 30 parts, Rhizoma Drynariae 100 parts, Conch Meretricis seu Cyclinae 20 parts.

The present invention can be prepared into any one with the method for Chinese medicinal of routine and commonly use water preparation, pill, powder by said medicine formula.As do ball powder type Chinese medicine composition can be pulverized respectively rear mixing thousand mesh sieves sieved after, with Mel with become honeyed pill, the heavy 6-9g of every ball.If do capsule formulation can load large size capsule (every is 1.0g).Avoid eating anything raw or cold, seafood, bean curd, medicated beer, different time strange land fruit and vegerable and various miscellaneous grain crops, as cold and cool nondigestible foods such as Fagopyrum esculentum Moench, highland barley powder, Fructus Momordicae charantiaes.

The applicant think diabetes be the traditional Chinese medical science quench one's thirst category (above disappear drink many, in disappear outeat, lower elimination of urine many, become thin), it will be argued that primary disease is the sun that cold-phlegm is stranded resistance three Jiao, mechanism of qi lose bad, because real causing void, because of pyrogenicity of trembling with fear, make the part of the body cavity above the diaphragm housing the heart and lungs can not as mist, middle Jiao can not as macerated, part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels Bu Neng, as Du, makes cloudy Tianjin not gasify and to rise, and this is sick all relevant with the vital organs of the human body, interior through cloud: " strengthening renal yin to inhibit predominant yang; to control sunlight, the source of beneficial water, with the be shaded or hidden for foliage that disappears ".The master of water---soil is (gram water person soil, and the fire energy immature soil, thus we only have warming YANG hometown native by force, could effectively harness the river) also, and the Overall View of the harmony between man and nature of the traditional Chinese medical science is thought, the earth 70% is water, and human body is also right.The large fixed star of the solar system nine rotates centered by the sun all (take fire as fortune, the four seasons development of evil in febrile disease thing of the earth, the life of all things on earth, length, strong, old, be extremely all with the discrepancy of yang-energy for power, so nourishing renal yang to restrict excessive yin, with the be shaded or hidden for foliage that disappears).Due to the not integration of modern's thought, particularly diet thought is westernization, the thought of traditional Chinese medical science Overall View is broken, too much cold and cool makes the body of Asians sun disappear, and totally (Asians is different with westerner's ethnic group, and westerner is based on the structure of carnivore, and intestinal body tubbiness, physique are tall and big, shorter than the intestinal of Asians 1.6 meters, thus dietary structure has different, and side's water and soil brings up a side people, therefore ancient speech: " five li different speech, Ten li apart, but the customs are quite different ".) the cold and cool sun making taste damages greatly, stomach lostization, spleen loses the lucid yang sending up, dry frozen ground duty in kidney, kidney fire is hindered greatly, without firewood at the bottom of still.Monoyin and monoyang is road for it, and cloudy strong sun is weak now.Postcoital protrusion then cloudy from, postcoital protrusion then the moon is deposited.Sweet flavour enters the spleen, spleen reinforcing is tired spleen also, and surfeit is sweet cold, and the cold then unable the lucid yang sending up of soil, then sweet leakage also.Interior through saying: " Sorghum vulgare Pers. savoury, the raw large furuncle of foot ", is the thing of surfeit savoury, gas is sun, taste is the moon, yang transforming qi, yin shaping up body.What thus our human body was wanted is yang transforming qi, therefore only has the gas of one sun heat, then negative water just can become running water, could water conservation.Interior through saying again: " two positive stasis disappear for it ", also, sun is strong then by the moon is stranded and cause knot, and postcoital protrusion is then fallen, and the moon must rise for the sun of two positive person brothers.Sun then not fallen without gesture by force, and the moon is then unable and rise therefore lower leakage, and thus warm native kidney tonifying fire (fire from the gater of life) treats the key of quenching one's thirst.The sun of human body is born in the part of the body cavity above the diaphragm housing the heart and lungs (cardiopulmonary), changes in middle Jiao (liver spleen), is hidden in the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels (kidney---the gate of vitality), moderns drunk enter room and the large wound of yang-energy.Again less than posteriori replenishing vital QI with drugs of warm nature, then more make to establish the yang function unable and damage sun and have a surplus, the prerequisite of YIN and YANG in a relative equilibrium is that in sun is hidden, the moon protects that it is outer therefore flat.As the shape of the earth, heart fire, the firm and biochemical all things on earth of shell.Modern medicine study shows, be positive ions in the nephrocyte of human body, and be negative electronics outward, just describing the thought of traditional Chinese medical science YIN and YANG in a relative equilibrium, normally (because two like magnetic poles repel each other, the molecular substance in animal body is negative to only have interior positive pudendum just can make the function of kidney, as glycan molecule, protein, macromolecular substances, yang transforming qi, the yin shaping up body of the traditional Chinese medical science have just in time confirmed this point), thus it will be argued that health preserving is being nourished heart, nourish heart therefore support fire.

Current treatment diabetes all moisturizing are main (hyperactivity of fire caused by deficiency of YIN), does not it know that water can be harnessed the river? only have and mend fire with strong soil, could deposit by sunization the moon, the husband sings and the wife follows.Therefore sun is kept also at interior the moon, sun making also at pudendum.

The present invention ask in line with curing the disease because of, treating both the principal and secondary aspects of a disease, the dialectical object treated, with warming YANG to expel cold, hometown kidney tonifying, effect a radical cure diabetes with water of cremating for method.In side, Radix Ginseng Rubra, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Poria are monarch drug, build spleen invigorating vital QI; Fructus Amomi, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Exocarpium Citri Rubrum, Semen Sinapis Albae, Semen Persicae, Flos Carthami are ministerial drug, build spleen and reduce phlegm, nourshing blood and promoting blood circulation disperse blood stasis and dredge collateral; Fructus Alpiniae Oxyphyllae, the Radix Linderae, Rhizoma Drynariae, Conch Meretricis seu Cyclinae for making medicine, warm native kidney tonifying, make gasification aobvious, hide sun and deposit the moon; Rhizoma Zingiberis warming spleen and stomach for dispelling cold.

Compatibility of the present invention is rigorous, and dialectical legislation side medicine is proper suits the medicine to the illness, and make diabetes not easily recur after healing, complication disappears, and blood glucose, glucose in urine recover normal.This prescription has no obvious toxic and side effects in clinical practice.Take through routine patient up to a hundred and do not find untoward reaction.

Clinical experiment

One, tcm diagnosis standard

Drink many, outeat, urinate many, become thin, weak (in conjunction with Western medicine diagnose).

Two, clinical scale

Divide two types, a type: insulin-dependent; Two types: kidney (kidney Distal convoluted tubule, proximal convoluted tubule are lost the absorption function of sugar, and pathomechanism is failed to understand)

Three, Therapeutic Method

1. choose 50 examples, take random packet own control relative method, compare the change of the symptom before and after patient treatment, sign and result.

2. make laws: warming YANG to expel cold, hometown kidney tonifying, strong soil are harnessed the river, with water of cremating.

3. method of administration: every day three times, each serving large size capsule 10-20 grain (every is 1.0g), serveing on March is a cycle, and half a year is a course for the treatment of.Primary symptom does not gently have other double disease, takes small dose drug; The heavy complications of primary symptom is many, takes heavy dose of medicine.

Four, clinical recovery: complication disappears, and blood glucose, glucose in urine are normal.

Five, therapeutic outcome

This medicine has no obvious toxic and side effects in clinical practice, and upper 50 routine patients take and do not find untoward reaction.In order to six courses for the treatment of of upper Regimen Chemotherapy, treatment 50 example, cure rate 80%, effective percentage 100%.General curative effect sees the following form one:

Detailed description of the invention

Embodiment 1

Side's medicine: Radix Ginseng Rubra 20g, Radix Astragali 100g, Rhizoma Atractylodis Macrocephalae 15g, Poria 15g, Fructus Amomi 15g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15g, Exocarpium Citri Rubrum 30g, Rhizoma Zingiberis 30g, Semen Persicae 15g, Flos Carthami 15g, Semen Sinapis Albae 30g, Fructus Alpiniae Oxyphyllae 20g, Radix Linderae 20g, Rhizoma Drynariae 30g, Conch Meretricis seu Cyclinae 15g.

Embodiment 2

Side's medicine: Radix Ginseng Rubra 80g, Radix Astragali 160g, Rhizoma Atractylodis Macrocephalae 30g, Poria 30g, Fructus Amomi 15g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20g, Exocarpium Citri Rubrum 30g, Rhizoma Zingiberis 30g, Semen Persicae 15g, Flos Carthami 30g, Semen Sinapis Albae 30g, Fructus Alpiniae Oxyphyllae 30g, Radix Linderae 30g, Rhizoma Drynariae 100g, Conch Meretricis seu Cyclinae 20 g.

Embodiment 3

Side's medicine: Radix Ginseng Rubra 100g, Radix Astragali 250g, Rhizoma Atractylodis Macrocephalae 30g, Poria 30g, Fructus Amomi 30g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 30g, Exocarpium Citri Rubrum 60g, Rhizoma Zingiberis 50g, Semen Persicae 20g, Flos Carthami 30g, Semen Sinapis Albae 60g, Fructus Alpiniae Oxyphyllae 50g, Radix Linderae 50g, Rhizoma Drynariae 100g, Conch Meretricis seu Cyclinae 30g.

The present invention can be prepared into any one with the method for Chinese medicinal of routine and commonly use water preparation, pill, powder by embodiment 1-3 Chinese medicine formula.As do ball powder type Chinese medicine composition can be pulverized respectively rear mixing thousand mesh sieves sieved after, with Mel with become honeyed pill, the heavy 6-9g of every ball.If do capsule formulation can load large size capsule (every is 1.0g).

Model case

Case one: field, man, 36 years old, owner of a private enterprise, first visit on August 5 in 2009, readme diabetes half a year, hospital diagnosis fasting glucose 11.2, without glucose in urine, glycolated hemoglobin 6.4, fasting insulin 5.3, it was more fat to examine human body, the light white no fur of tongue body, dry lip.Pulse-taking six deficient and large pulse, heavily by unable, two hands chi pulses are slightly tight.Legislation: warming YANG, the kidney invigorating, hometown, cold expelling, invigorate blood circulation, blood stasis dispelling, regulate the flow of vital energy, the strong gate of vitality.Method of administration is pulverized prescription drugs and is filled No. 1 capsule (every capsules 1g crude drug), each serving with 15, one day daytime three times, takes medicine morning once, 20.After serveing on 6 courses for the treatment of, through many examination in hospital, indices recovers normal, and subjective symptoms disappears, physically and mentally healthy joyful.

Case two: river, man, 56 years old, Yushu district, Qinghai cadre, first visit on October 2 in 2009, readme diabetes 10 years, subjective symptoms is weak, thirsty, frequent micturition frequent micturition, people is black and thin, and with hypertension, hyperlipemia, long-term taking oral insulin, the hypoglycemic medicines such as metformin, the people that can diagnose a disease carries case, display hyperglycemia, hyperinsulinemia (glycolated hemoglobin 10.08, fasting insulin 16.8, urine protein ++, glucose in urine +++), human body is had a haggard face black and thin, neurolysis, weak, tongue body slight of stature is dark red, cannot outside extending port, the dark stagnant cyanosis of lip, pulse-taking six kinds of pulses lies prostrate and heavy stringy and thready pulse is tight.Legislation: warming YANG, the kidney invigorating, hometown, cold expelling, invigorate blood circulation, blood stasis dispelling, regulate the flow of vital energy, the strong gate of vitality.Method of administration is pulverized prescription drugs and is filled No. 1 capsule (every capsules 1g crude drug), and each serving with 20, every three hours of daytime took once, and every 6 hours of evening took once.After serveing on 6 courses for the treatment of, through many examination in hospital, indices recovers normal, and subjective symptoms disappears, physically and mentally healthy joyful.

Case three: Zhang, man, 47 years old, doctor, first visit on May 7 in 2002, patient's readme is weak, frequent micturition frequent micturition, pain in the lumbar region is also easily sprained, to examination in hospital glucose in urine ++, fasting glucose 8.7, do not take any remedy measures, self-contr ol diet to 2007 year, July then, suddenly there is blurred vision in patient, trick pain, palpitation and short breath, Pruritus from head to foot, oral ulcer, have a sleepless night weak, the symptoms such as erythra, after examination in hospital, be diagnosed as type-II diabetes, hospitalization, beat insulin novolin every day 2 times, before lunch, half an hour sprays novolin 28 units, under a.p spray promise and woods 24 units, at treatments period, complication not anti-reflection increases (urine protein ++++, glucose in urine ++++, cardiac extra systole, arrhythmia, multiple hepatorenal cyst, 1/3 loss of tooth, optical fundus is muddy).People is yellow black and thin, and body weight falls sharply in one month 20kg, and weak few speech, insomnia is impatient, scatters and disappears and cures conviction.Honorable color of can diagnosing a disease is steel gray, burned blackly becomes thin, lazy speech of speaking in a low voice, and inspection of the tongue tongue body is livid purple and aged, turbid thick and greasy fur, mouth raw meat halitosis, pulse-taking six floating and large pulse and removing from office, the arteries and veins of YANG-depletion consumption of essence.Legislation: warming YANG, the kidney invigorating, hometown, cold expelling, invigorate blood circulation, blood stasis dispelling, regulate the flow of vital energy, the strong gate of vitality.Method of administration to decoct water preparation, first takes half a year prescription drugs, and every four hours day and night once, stops beating insulin.Take water preparation after one month, patient's nocturia of drinking water reduces, and hypoglycemia disappears, and hungry more than one hour of ability, remaining disease alleviates, and does not check physical and chemical index.After continuous half a year of taking medicine, clinical symptom disappearance, the mental status is improved greatly, checks physical and chemical index glycolated hemoglobin 6.8, and urine protein, fatty liver disappear, glucose in urine+, body weight increases 1kg, and patient cures confidence increases.Change and take No. 1 capsule (every capsules 1g crude drug), each serving with 20, every 3 hours of daytime took 1 time, and every 6 hours of evening took 1 time.After 4 courses for the treatment of, on inspection, the every physical and chemical index of patient is normal, and vision, heart etc. recover normal, and through ultrasound diagnosis, hepatorenal cyst disappears, and physical recovery is healthy.

Claims (2)

1. treat a medicine for diabetes, it is characterized in that it is made up of the raw material of following weight parts proportioning:

Radix Ginseng Rubra 20-100 parts, the Radix Astragali 100-250 parts, the Rhizoma Atractylodis Macrocephalae 15-30 parts, 15-30 parts, Poria, Fructus Amomi 15-30 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15-30 parts, Exocarpium Citri Rubrum 30-60 parts, Rhizoma Zingiberis 30-50 parts, 15-20 parts, Semen Persicae, 15-30 parts, Flos Carthami, Semen Sinapis Albae 30-60 parts, Fructus Alpiniae Oxyphyllae 20-50 parts, the Radix Linderae 20-50 parts, Rhizoma Drynariae 30-100 parts, Conch Meretricis seu Cyclinae 15-30 parts.

2. the medicine for the treatment of diabetes according to claim 1, is characterized in that it is made up of the raw material of following weight parts proportioning:

Radix Ginseng Rubra 80 parts, the Radix Astragali 160 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, 30 parts, Poria, Fructus Amomi 15 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20 parts, Exocarpium Citri Rubrum 30 parts, Rhizoma Zingiberis 30 parts, 15 parts, Semen Persicae, 30 parts, Flos Carthami, Semen Sinapis Albae 30 parts, Fructus Alpiniae Oxyphyllae 30 parts, the Radix Linderae 30 parts, Rhizoma Drynariae 100 parts, Conch Meretricis seu Cyclinae 20 parts.