CN105343646A

CN105343646A - Traditional Chinese medicine for preventing and treating non-gonococcal urethritis and preparation method thereof

Info

Publication number: CN105343646A
Application number: CN201510945692.1A
Authority: CN
Inventors: 夏修菲
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-12-17
Filing date: 2015-12-17
Publication date: 2016-02-24

Abstract

The invention discloses a traditional Chinese medicine for preventing and treating non-gonococcal urethritis and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The effective ingredient of the traditional Chinese medicine consists of the following raw materials: Chinese yam, dandelion, astragalus membranaceus, oldenlandia diffusa, herba portulacae, salvia miltiorrhiza, dried radix rehmanniae, fructus lycii, rhizoma atractylodis macrocephalae, houttuynia cordata, angelica sinensis, achyranthes bidentata, ardisia crispa, rhizoma dioscoreae hypoglaucae, rhizoma atractylodis, lophatherum gracile, licorice root, felwort, cistanche salsa, eupatorium chinense, caulis akebiae and fistular onion stalk. The traditional Chinese medicine is prepared according to exogenous damp-heat evil toxicity, body kidney-qi deficiency and other symptoms, and has the effects of treating stranguria, removing toxicity, invigorating spleen for eliminating dampness, promoting blood circulation to remove stasis, tonifying qi and nourishing yin. Clinical application verifies that the traditional Chinese medicine has a good absorption effect, has a remarkable curative effect on non-gonococcal urethritis, does not have toxic effect, side effect or adverse response, and has a good clinical popularization application prospect.

Description

A kind of for Chinese medicine preventing and treating nongonococcal urethritis and preparation method thereof

Technical field

The present invention relates to the field of Chinese medicines, particularly relate to a kind of for Chinese medicine preventing and treating nongonococcal urethritis and preparation method thereof, the nongonococcal urethritis that excess of sexual intercourse, the damp and hot excessive poison of diseases caused by exogenous pathogenic factor, ferritic kidney qi virtual loss are caused provide a kind of health, effectively, a kind of new medicine prescription of having no side effect.

Background technology

Nongonococcal urethritis is a kind of sexually transmitted disease (STD) caused by chlamydia trachomatis and Ureaplasma urealyticum etc.Have the performance of urethritis clinically, typical performance has urethra scratchy, with urgent micturition, dysurea and dysuria, but symptom comparatively gonococcal urethritis is light.Before the long period does not urinate or early morning urinates first, gum duct mouth can go out a small amount of mucus secretions, sometimes only shows as the sealing of crust film or crotch filth.There is quite a few people can without any symptom.Can there is epididymitis in male patient, female patient is not as male typical case, and a lot of patient can be asymptomatic, generally urethritis, mucopurulent cervicitis, acute pelvic inflammatory disease and infertility etc. can occur.

Modern medical techniques diagnosis and treatment confirm, nongonococcal urethritis is a kind of common sexually transmitted disease (STD) caused by chlamydia trachomatis, Ureaplasma urealyticum etc.Nongonococcal urethritis is a kind of syndrome of multi-pathogenesis, the nongonococcal urethritis of 30% ~ 50% is relevant with chlamydia trachomatis, 20% ~ 30% is ureaplasma urealyticum infection, 10% is that the chlamydia that causes of the per vaginam microorganism such as trichomonacide, Candida albicans, herpes simplex virus, mycoplasma genitalium, adenovirus and bacillus and mycoplasma External Environment resistance are more weak, can be killed at 5 ~ 10 minutes after heating 56 DEG C, it also can kill by common disinfectants such as formalin, lysol, carbolic acid easily.

Clinically, at present for the treatment of nongonococcal urethritis, mainly contain injection ofloxacin, azithromycin, cefazolin, Ceftriaxone, penicillin for treatment, oral mainly contains erythromycin, the treatment meanss such as Roxithromycin, streptomycin, rifampicin, tetracycline.The short term clinical excellent effect of doctor trained in Western medicine, but long-term taking antibiotic all produces fastbacteria, causes original pathogenic bacteria continued propagation in body, side effect is larger, and complication day by day increases, thus cause recurrence or the obstinate of nongonococcal urethritis, delay best treatment time.

Traditional Chinese Medicine means are when diagnosis and treatment, common have urine leaching pure not smooth, or urethral orifice has foul logistics to go out, or leukorrhagia is abnormal, lower abdominal distention pain, tongue is dark, tongue is white, stringy and thready pulse, and this is generally due to pathogen usually intruding into collateral in protracted disease, or due to damp and hot evil obstruction of meridian, caused by qi and blood stagnation, the cause of disease many because sexual life is unclean, the damp and hot excessive poison of excess of sexual intercourse, diseases caused by exogenous pathogenic factor, ferritic kidney qi virtual loss about relevant with kidney, bladder, taste and liver, be mark with wet, heat, poison, the stasis of blood, disharmony between QI and blood, kidney qi (essence) virtual loss is this, and card belongs to deficiency in origin and excess in superficiality.Therefore, for its pathogenesis, according to theory of Chinese medical science, should start with from aspects such as solution damp and hot heresy, qi and blood stagnations, adopt the prescription that profit drenches dampness removing, row's stasis of blood leads to resistance, patient body is nursed one's health.

The proved recipe that conventional flow hands down, classical prescription, and existing neoteric Chinese prescription, the plurality of Chinese compatibility for the treatment of stranguria dampness removing is adopted to concoct, be generally the prescription getting heat-clearing and toxic substances removing, bactericidal antiphlogistic, inducing diuresis for treating stranguria syndrome, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, nourishing liver and kidney, make decoction or other suitable dosage form.The road of Founder got by these Chinese medicines, really can play the effect consolidating real argument, but compared with directly killing pathogenic bacterium with the specific aim of Western medicine, its onset is slow, and therapeutic effect is very undesirable.

This technological invention people is for this problem, after deeply thinking deeply, Herba Cistanches, Herba Serissae, Caulis Akebiae are added prescription as ministerial drug, simultaneously with Bulbus Allii Fistulosi for drawing, in the hope of the effect that a winding path leads to quiet seclusion---the Main Function of Herba Cistanches is that the kidney invigorating yang deficiency declines, and be generally used for sexual impotence, tinnitus order flower, the infertility for the treatment of asthenia of essence and blood, the present invention takes Herba Cistanches, then mainly get the effect of its treatment dryness of the intestine constipation, real mutually in the hope of letting out benefit; Herba Serissae and Caulis Akebiae are all toxic, tradition classical prescription, proved recipe all have its usage and dosage strict to be prevented, avoids, with Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae, the base of the Rhizoma Atractylodis Macrocephalae for consolidating in the present invention, get Herba Lophatheri, the function of detoxification of Radix Glycyrrhizae is in harmonious proportion, avoid Herba Serissae, Caulis Akebiae toxicity to the infringement of body, retain its heat clearing away of dispeling cold, dispersing liver and promoting blood circulation, edema of dispelling simultaneously, control effect of damp and hot arthralgia pain, the monarch and his subjects help mutually, cure the sickness to save the patient.

Summary of the invention

For solving the defect existed in prior art, the invention provides a kind of for Chinese medicine preventing and treating nongonococcal urethritis and preparation method thereof, there is effect for the treatment of stranguria removing toxic substances, invigorating the spleen for eliminating dampness, blood circulation promoting and blood stasis dispelling, supplementing QI and nourishing YIN, good absorbing effect, evident in efficacy, without any side effects and the untoward reaction through clinical verification, is applicable to large-scale popularization application.

For achieving the above object, technical scheme of the present invention is implemented as follows:

For preventing and treating a Chinese medicine for nongonococcal urethritis, raw material composition and the parts by weight of making described effective ingredient are:

Rhizoma Dioscoreae 30 parts ~ 65 parts, Herba Taraxaci 30 parts ~ 60 parts, the Radix Astragali 20 parts ~ 35 parts, Herba Hedyotidis Diffusae 30 parts ~ 60 parts, Herba Portulacae 30 parts ~ 55 parts, Radix Salviae Miltiorrhizae 25 parts ~ 35 parts, Radix Rehmanniae 25 parts ~ 35 parts, Fructus Lycii 12 parts ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts ~ 25 parts, Herba Houttuyniae 15 parts ~ 25 parts, Radix Angelicae Sinensis 12 parts ~ 20 parts, Radix Achyranthis Bidentatae 12 parts ~ 20 parts, Radix Ardisiae Crispae 10 parts ~ 18 parts, Rhizoma Dioscoreae Hypoglaucae 12 parts ~ 18 parts, Rhizoma Atractylodis 8 parts ~ 15 parts, Herba Lophatheri 8 parts ~ 15 parts, 10 parts ~ 18 parts, Radix Glycyrrhizae, Radix Gentianae 8 parts ~ 15 parts, Herba Cistanches 8 parts ~ 13 parts, Herba Serissae 6 parts ~ 12 parts, Caulis Akebiae 3 parts ~ 8 parts, Bulbus Allii Fistulosi 2.

Raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are:

Rhizoma Dioscoreae 40 parts ~ 50 parts, Herba Taraxaci 40 parts ~ 50 parts, the Radix Astragali 26 parts ~ 30 parts, Herba Hedyotidis Diffusae 40 parts ~ 50 parts, Herba Portulacae 40 parts ~ 48 parts, Radix Salviae Miltiorrhizae 28 parts ~ 32 parts, Radix Rehmanniae 28 parts ~ 32 parts, Fructus Lycii 15 parts ~ 18 parts, the Rhizoma Atractylodis Macrocephalae 18 parts ~ 22 parts, Herba Houttuyniae 18 parts ~ 22 parts, Radix Angelicae Sinensis 15 parts ~ 17 parts, Radix Achyranthis Bidentatae 15 parts ~ 17 parts, Radix Ardisiae Crispae 12 parts ~ 15 parts, Rhizoma Dioscoreae Hypoglaucae 14 parts ~ 16 parts, Rhizoma Atractylodis 10 parts ~ 12 parts, Herba Lophatheri 10 parts ~ 12 parts, 13 parts ~ 15 parts, Radix Glycyrrhizae, Radix Gentianae 10 parts ~ 12 parts, Herba Cistanches 10 parts ~ 11 parts, Herba Serissae 8 parts ~ 10 parts, Caulis Akebiae 5 parts ~ 6 parts, Bulbus Allii Fistulosi 2.

Rhizoma Dioscoreae 35 parts, Herba Taraxaci 35 parts, the Radix Astragali 25 parts, Herba Hedyotidis Diffusae 35 parts, Herba Portulacae 35 parts, Radix Salviae Miltiorrhizae 26 parts, Radix Rehmanniae 26 parts, Fructus Lycii 13 parts, the Rhizoma Atractylodis Macrocephalae 16 parts, Herba Houttuyniae 16 parts, Radix Angelicae Sinensis 13 parts, Radix Achyranthis Bidentatae 13 parts, Radix Ardisiae Crispae 11 parts, Rhizoma Dioscoreae Hypoglaucae 13 parts, Rhizoma Atractylodis 9 parts, Herba Lophatheri 9 parts, 12 parts, Radix Glycyrrhizae, Radix Gentianae 9 parts, Herba Cistanches 9 parts, Herba Serissae 7 parts, Caulis Akebiae 4 parts, Bulbus Allii Fistulosi 2.

Rhizoma Dioscoreae 60 parts, Herba Taraxaci 55 parts, the Radix Astragali 33 parts, Herba Hedyotidis Diffusae 55 parts, Herba Portulacae 52 parts, Radix Salviae Miltiorrhizae 33 parts, Radix Rehmanniae 33 parts, Fructus Lycii 19 parts, the Rhizoma Atractylodis Macrocephalae 23 parts, Herba Houttuyniae 23 parts, Radix Angelicae Sinensis 18 parts, Radix Achyranthis Bidentatae 18 parts, Radix Ardisiae Crispae 16 parts, Rhizoma Dioscoreae Hypoglaucae 17 parts, Rhizoma Atractylodis 13 parts, Herba Lophatheri 13 parts, 16 parts, Radix Glycyrrhizae, Radix Gentianae 13 parts, Herba Cistanches 12 parts, Herba Serissae 11 parts, Caulis Akebiae 7 parts, Bulbus Allii Fistulosi 2.

Rhizoma Dioscoreae 45 parts, Herba Taraxaci 45 parts, the Radix Astragali 28 parts, Herba Hedyotidis Diffusae 45 parts, Herba Portulacae 45 parts, Radix Salviae Miltiorrhizae 30 parts, Radix Rehmanniae 30 parts, Fructus Lycii 16 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Herba Houttuyniae 20 parts, Radix Angelicae Sinensis 16 parts, Radix Achyranthis Bidentatae 16 parts, Radix Ardisiae Crispae 13 parts, Rhizoma Dioscoreae Hypoglaucae 15 parts, Rhizoma Atractylodis 11 parts, Herba Lophatheri 11 parts, 14 parts, Radix Glycyrrhizae, Radix Gentianae 11 parts, Herba Cistanches 10 parts, Herba Serissae 9 parts, Caulis Akebiae 5 parts, Bulbus Allii Fistulosi 2.

For preventing and treating a preparation method for the Chinese medicine of nongonococcal urethritis, comprise following processing step:

(1) by Rhizoma Dioscoreae, Radix Rehmanniae, Radix Angelicae Sinensis, Rhizoma Dioscoreae Hypoglaucae, Herba Portulacae, Radix Glycyrrhizae, Radix Ardisiae Crispae, Herba Cistanches, Caulis Akebiae decontamination, be soaked in water to softening, pulling out slightly dries in the air when being suitable for inside and outside humidity, and section is dried or dried, for subsequent use;

(2) by Herba Taraxaci, Herba Houttuyniae, Radix Achyranthis Bidentatae, Herba Lophatheri decontamination, clean, cutting, dries or dries, for subsequent use;

(3) by Radix Astragali roguing root, dry, for subsequent use;

(4) by Radix Gentianae, Herba Hedyotidis Diffusae, Herba Serissae, Bulbus Allii Fistulosi decontamination, clean, for subsequent use;

(5) by Radix Salviae Miltiorrhizae decontamination, clean, section, dries, gets Radix Salviae Miltiorrhizae Tabellae and pour in pot, with surperficial micro-Jiao of the micro-stir-fry of slow fire, takes out, cools, for subsequent use;

(6) by Rhizoma Atractylodis Macrocephalae decontamination, pull out after immersion, section, dries, gets Rhizoma Atractylodis Macrocephalae sheet and pour in pot, be faint yellow with the micro-stir-fry of slow fire to epidermis, and taking-up is for subsequent use;

(7) by Rhizoma Atractylodis decontamination, clean, be dipped to seven, most probably thoroughly, pull out, section, dries, gets Rhizoma Atractylodis sheet and pour in pot, fries to surperficial micro-Jiao with high heat, takes out, cool, for subsequent use;

(8) by step 1g ~ step 7 standby crude drug, pour in marmite, add the water of octuple amount, immersion 2g ~ 2.5 hour, add Fructus Lycii and Bulbus Allii Fistulosi decocted with high heat to boiling after 30 minutes, use slow fire instead and continue decoction 2 hours, get immersion, obtained described Chinese medicine decoction.

(9) by the immersion of step 8 gained, with modern production process, carry out sterilizing, concentrated, dry, pulverize, sieve, tabletting, dissolved granule, capsule, the tablet of obtained described Chinese medicine.

The property of medicine of the present invention's Chinese medicine used is as follows:

Rhizoma Dioscoreae: sweet in the mouth; Property is put down.Enter lung; Spleen; Kidney channel.Spleen reinforcing; Support lung; Reinforce the kidney; Benefit essence.Cure mainly diarrhea due to hypofunction of the spleen; Lack of appetite edema; Seminal emission; Leukorrhagia; To suffer from a deficiency of the kidney frequent micturition; Scrofula." book on Chinese herbal medicine just " carries: " Rhizoma Dioscoreae, energy spleen invigorating tonify deficiency, grows essence and reinforce the kidney, control weakness, treat five kinds of strain and seven kinds of impairment.”

Herba Taraxaci: bitter in the mouth; Sweet; Cold in nature.Return liver; Stomach warp.Heat-clearing and toxic substances removing; Eliminating carbuncle eliminating stagnation.Cure mainly acute mastitis; Lung abscess; Intestinal carbuncle; Mumps; Furuncle carbuncle toxin; Stomach-fire; Intestinal is scorching; Dysentery; Hepatitis; Cholecystitis; Urinary tract infection.Clinic study shows, dandelion preparation can replace antibiotics to use to a certain extent, some disease indicia is gone out to effect of broad-spectrum antibiotic, has certain antiviral functions.

The Radix Astragali: sweet in the mouth; Warm in nature.Enter the heart; Lung; Spleen; Kidney channel.Invigorating QI to consolidate the body surface resistance; Diuresis; Expelling pus and toxin by strengthening QI; Promoting tissue regeneration and ulcer healing.Cure mainly cardiopalmus of breathing hard; Asthenia; Weak; Spontaneous perspiration; Night sweat; Chronic diarrhea; Proctoptosis; Body is impractical swollen; Uterine prolapse; Chronic nephritis; Carbuncle difficulty is burst; Or burst do not hold back for a long time." Xinhua's book on Chinese herbal medicine outline " carries: " have the function of invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, granulation promoting.”

Herba Hedyotidis Diffusae: bitter in the mouth; Sweet; Cold in nature; Nontoxic.Enter the heart; Liver; Spleen; Large intestine channel.Heat-clearing and toxic substances removing; Dampness removing.Cure mainly intestinal carbuncle; Furuncle and phyma skin infection; The puckery pain of pyretic stranguria; Edema; Dysentery; Intestinal is scorching; Jaundice due to damp-heat; Cancerous protuberance." Quanzhou book on Chinese herbal medicine " carries: " heat clearing away dissipating blood stasis, eliminating carbuncle detoxifies.Control ulcer sores, scrofula ".

Herba Portulacae: acrid in the mouth; Acid; Cold in nature; Nontoxic.Enter large intestine, liver, spleen channel.Heat-clearing and toxic substances removing; Cooling blood for hemostasis; Loose blood detumescence.Treatment of ulcer carbuncle furuncle; Scrofula; Temperature tinea.

Radix Salviae Miltiorrhizae: bitter in the mouth; Cold nature; Nontoxic.Enter the heart; Liver Channel.Promoting blood flow to regulate menstruation; Stasis-dispelling and pain-killing; Removing heat from blood eliminating carbuncle; Clear away heart-fire relieving restlessness; Nourishing blood to tranquillize the mind.Cure mainly trusted subordinate's pathogen; Cold and heat gather; Ailment said due to cold or exposure stays heat." herbal classic " carries: " main trusted subordinate's pathogen, borborygmus are faint as leaked water, and cold and heat gather; Broken disease, except abdominal mass, stops stuffy sensation with restlessness, QI invigorating.”

Radix Rehmanniae: sweet in the mouth; Bitter; Be slightly cold.GUIXIN; Liver; Kidney channel.For nourishing YIN and clearing away heat; Removing heat from blood is enriched blood.Cure mainly calentura excessive thirst; Interior-heat is quenched one's thirst; Hectic fever due to YIN-deficiency consumptive fever; Epidemic febrile disease sends out speckle; Haematemesis caused by heat in blood; Metrorrhagia; Hematuria; Have blood in stool; Blood deficiency and yellow complexion; Dizzy cardiopalmus; Insufficiency of blood amenorrhea.

Fructus Lycii: sweet in the mouth; Property is put down.Return liver; Kidney; Lung meridian.Nourishing the liver; Nourishing kidney; Lung moistening.Cure mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual one clear; Soreness of the waist and knees; The expensive essence of sexual impotence; To quench one's thirst taking fluids profusely." book on Chinese herbal medicine just " carries: " improve visual and auditory acuity, adds the solid marrow of essence, strengthen the muscle and bone, and kind benefit impairment caused by overstrain, especially only quenches one's thirst.”

The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; Stomach warp.Invigorating the spleen and benefiting QI; Dampness diuretic; Hidroschesis; Antiabortive.Cure mainly deficiency-weakness of spleen-QI; Spiritlessness and weakness; Lack of appetite abdominal distention; Large loose stool is thin; Fluid-retention stagnating in the interior; Dysuria; Edema; Dizziness due to fluid-retention; Arthralgia chiefly caused by damp pathogen is ached; Spontaneous sweating due to deficiency of QI; Frequent fetal movement." herbal classic is met former " carries: " art, raw with there being dehumidifying benefit dry, expectorant diuretic, controls anemofrigid-damp arthralgia, dead flesh convulsion subcutaneous ulcer, blood between loose waist umbilicus, and chong channel is disease, the merit of inverse gas pain in the abdomen; Make ripe, have and middle QI invigorating, slake thirst and help produce saliva, hidroschesis heat extraction, enters diet, antiabortive effect.”

Herba Houttuyniae: acrid in the mouth; Cold in nature.Enter liver; Lung meridian.Heat-clearing and toxic substances removing; Removing pus and relieving carbuncle; Inducing diuresis for treating stranguria syndrome.Cure mainly lung abscess vomiting pus; Hematodiarrhoea; Carbuncle sore tumefacting virus; Pyretic stranguria." conventional Chinese herbal medicine handbook " carries: " eliminating inflammation and expelling toxin, inducing diuresis to remove edema.Control upper respiratory tract infection, lung abscess, urinary tract inflammation and other position suppurative inflammation." modern medicine study confirmation; Herba Houttuyniae can strengthen the phagocytic activity of WBC; improve immunity of organisms; all have inhibitory action to various microorganism, also has significant antagonism, antiviral, diuresis, analgesia, antitussive, hemostasis, suppression serous secretion in addition, promotes tissue regeneration, calmness, anticonvulsant action.

Radix Angelicae Sinensis: sweet in the mouth; Pungent; Warm in nature.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation; Menstruction regulating and pain relieving; Loosening bowel to relieve constipation.Cure mainly blood deficiency and yellow complexion; Dizzy cardiopalmus; Asthenia cold abdominalgia; Rheumatic arthralgia; Ulcer sores." book on Chinese herbal medicine is just " carries: " its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, nothing unsuitable.”

Radix Achyranthis Bidentatae: sweet in the mouth; Micro-hardship, property is put down.Return liver, kidney channel.Eliminating blood stasis and inducing menstruation; Easing joint movement; Inducing diuresis for treating stranguria syndrome.For amenorrhea lump in the abdomen; Retention of placenta; Arthralgia; Flaccidity of the lower limbs clonic spasm of the muscle; Injury from falling down." Chinese medicinal herbal " carries: " removing blood stasis declines, and controls to beat and flutters knife injury, have the effect relaxing pain." modern medicine study confirmation, Radix Cyathulae has obvious analgesic activity, and contained insectean metamorphosis steroid hormone and Herba Cyathulae Prostratae steroid paulownia have protein assimilation.

Radix Ardisiae Crispae: bitter in the mouth; Pungent; Cool in nature.For relieving sore-throat by clearing away heat; Promoting blood circulation and detoxication.Cure mainly laryngopharynx swelling and pain; Cough is coughed up phlegm not smooth, jaundice due to damp-heat; Urine leaching pain; Rheumatic arthralgia; Traumatic injury; Furuncle; Innominate toxic swelling.

Rhizoma Dioscoreae Hypoglaucae: bitter in the mouth; Property is put down.Enter liver; Stomach; Urinary bladder channel.Wind-damp dispelling; Dampness removing is turbid.Cure mainly stranguria marked by chyluria; Nebulousurine; Leukorrhagia; Skin infection; Eczema; Rheumatic arthralgia." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control wind and cold, warming the meridian network, waist knee joint aches, stupid fiber crops all over, sharp wing dehydration channel, red white turbid urine." modern medicine study shows; dioscorea sapotoxin contained in Rhizoma Smilacis rhizome has insecticidal action; Saponin has intends choline-like effect; can expand peripheral vessel, reduce blood pressure, strengthen the motion of gastrointestinal smooth muscle; improve blood glucose, faint from fear to chemical resistance, reduce serum cholesterol; improve the permeability of each tissue, also have the effect significantly reducing atherosclerosis class block incidence rate in addition.

Rhizoma Atractylodis: acrid in the mouth; Bitter; Warm in nature.Return spleen; Stomach; Liver Channel.Drying damp and strengthening spleen; Wind-damp dispelling; Improving eyesight.Cure mainly the spleen and stomach being stranded by dampness; Asthenia drowsiness; Born of the same parents' painful abdominal mass abdominal distention; Inappetence; Vomiting is had loose bowels; Damp-edema; Exterior syndrome folder is wet; Head heavy sensation of the body pain; Arthromyodynia warm nature; Podomere is ached serious symptom; Flaccidity folds in a garment; Nyctalopia." beautiful Chinese catalpa medicine solution " carries: " dry native diuretic, lets out drink expectorant, clots absorbing, dissipating depression of QI, goes Lou, changes addiction, and except disease, reason acid regurgitation removing the necrotic tissue, ward off mountains and rivers communicable subtropical diseases, the flaccidity returning muscles and bones is soft, excessive muddiness of urinating clearly." modern medicine study confirmation, volatile oil contained by Rhizoma Atractylodis has dispelling-wind invigorating stomach effect, and contained bitterness also has stomach invigorating, appetitive effect.

Herba Lophatheri: sweet in the mouth; Light; Cold in nature.GUIXIN; Small intestinal; Lung; Stomach warp.Heat clearing away; Relieving restlessness; Diuresis.Cure mainly dysphoria with smothery sensation thirsty; Aphtha of the mouth and tongue; Gingival swelling and pain; Children's's night crying due to fright in infant; Hot urination; Stranguria with turbid discharge." the SHENGCAO property of medicine standby will " carries: " expectorant is quenched the thirst, and except part of the body cavity above the diaphragm housing the heart and lungs fire, bright eyes, diuresis, controls nebulousurine, brings down a fever, loose hemorrhoid poison." modern medicine study shows, Herba Lophatheri has significant refrigeration function, can increase the excretion of urine chloride.

Radix Glycyrrhizae: sweet in the mouth; Property is put down.GUIXIN; Lung; Spleen; Stomach warp.Invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Relieving spasm to stop pain; Coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach; Fatigue and weakness; Shortness of breath and palpitation; Gastral cavity abdomen four muscle spasm of the leg and foot pain; Carbuncle sore tumefacting virus; Cushion toxicity.Compendium of Material Medica is carried: " in all medicines, Radix Glycyrrhizae is monarch.Control 72 kinds of mammary calculus poison, draft is malicious by every means to separate 1,002, is in harmonious proportion from medicine and gains merit.”

Radix Gentianae: bitter in the mouth; Cold in nature.Enter the heart; Lung; Stomach; Large intestine channel.Clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body.Cure mainly jaundice; Dysentery; Have blood in stool; Dysuria; Infantile malnutrition; Skin infection; Toxic swelling." conventional Chinese herbal medicine handbook " carries: " heat clearing away, dehumidifying, removing toxic substances, pain relieving, stomach invigorating.Control poison of drug, sun stroke belly pain, lumbago, endometritis, jaundice, stomachache, dyspepsia.”

Herba Cistanches: sweet in the mouth; Salty; Warm in nature.Return kidney; Large intestine channel.Kidney-replenishing; Benefiting essence-blood; Intestine moistening road.Cure mainly kidney yang deficiency; Lumbago flaccidity of the lower limbs." herbal classic " carries: " main five kinds of strain and seven kinds of impairment, invigorating middle warmer, except stem invasion by pathogenic cold burning pain, support the five internal organs, reinforcing YIN-essence, beneficial vital essence." " book on Chinese herbal medicine converge with speech " carry: " temperature and not hot, mends and not high, warm and not dry, sliding and do not let out, therefore has calm name." modern medicine study confirmation, Herba Cistanches all has potentiation to body fluid and cellular immunization, can promote the formation of lymphocyte Ea bow structure.

Herba Serissae: acrid in the mouth; Micro-hardship; Property micro-wet.Return liver; Spleen channel.Promoting blood circulation to restore menstrual flow; Blood stasis dispelling row water.Cure mainly menoxenia; Dysmenorrhea; Amenorrhea; Puerperal abdonimal pain; WEIJIA; Body and face edema; Carbuncle; Traumatic injury." Chinese herbal medicine is commonly used in Sichuan " carries: " Herba Strobilanthis Japonici, the capable water of repercussive, soothing liver-QI falls apart strongly fragrant." modern medicine study confirms, Herba Strobilanthis Japonici containing volatile oil, tannin, phenols and several amino acids, can prevent thrombosis, have slight anticoagulant system with the effect strengthening fibrinolytic.

Caulis Akebiae: bitter in the mouth; Cold in nature; Poisonous.Enter the heart; Small intestinal; Urinary bladder channel.Clearing heart fire; Treating stranguria; Stimulating milk secretion is stimulated the menstrual flow.Cure mainly hot urination; Pouring brimful of tears; Edema; Dysphoria with smothery sensation in the heart; Aphtha of the mouth and tongue; Leucorrhea; Amenorrhea; Puerperal galactostasis; Damp and hot arthralgia pain." Chinese Pharmacopoeia " carries: " purge heat, pathogenic fire reducing.Control aphtha of the mouth and tongue, hot urination." modern medicine study confirmation, the aristolochic acid A contained by Caulis Akebiae has the cytophagous phagocytic function of enhancing, can improve cellular immune function, have significant diuresis.

Bulbus Allii Fistulosi: acrid in the mouth; Warm in nature.Return lung; Stomach warp.For delivering; Activate yang; Removing toxic substances; Parasite killing.Cure mainly cold; YIN-cold is suffered from abdominal pain; Constipation and anuresis; Dysentery; Sore, carbuncle and painful swelling; Abdominal pain due to worm stagnation.Zhang Yuansu: Herba Alii fistulosi stem "white expert" master disperses, with logical upper and lower yang-energy, the cold severe splitting headache therefore " living person's book " cures the wound, with Radix Allii Fistulosi soup master it; Zhang Zhongjing controls SHAO YIN syndrome watery diarrhea with indigested food, cold in the interior and heat in the exterior, and faint inverse faint pulse person, Bai Tongtang master it, interior Bulbus Allii Fistulosi, if flushed face person, cold limbs Tonga Bulbus Allii Fistulosi, abdominal pain person, goes Bulbus Allii Fistulosi.The cloud of Cheng Wuji solution, the kidney being adverse to tryness, instant pungent to moisten it, the pungent temperature of Bulbus Allii Fistulosi, to activate yang gas also.

The present invention compared with prior art, has following beneficial effect:

The present invention selects medical material to meet a monarch and his subjects left side and makes it reason, has effect for the treatment of stranguria removing toxic substances, invigorating the spleen for eliminating dampness, blood circulation promoting and blood stasis dispelling, supplementing QI and nourishing YIN, good absorbing effect, evident in efficacy, and the without any side effects and untoward reaction through clinical verification is applicable to large-scale popularization application.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further elaborated.

Embodiment 1

The raw material composition of Effective Component of Chinese Medicine of the present invention and weight are:

Rhizoma Dioscoreae 35g, Herba Taraxaci 35g, Radix Astragali 25g, Herba Hedyotidis Diffusae 35g, Herba Portulacae 35g, Radix Salviae Miltiorrhizae 26g, Radix Rehmanniae 26g, Fructus Lycii 13g, Rhizoma Atractylodis Macrocephalae 16g, Herba Houttuyniae 16g, Radix Angelicae Sinensis 13g, Radix Achyranthis Bidentatae 13g, Radix Ardisiae Crispae 11g, Rhizoma Dioscoreae Hypoglaucae 13g, Rhizoma Atractylodis 9g, Herba Lophatheri 9g, Radix Glycyrrhizae 12g, Radix Gentianae 9g, Herba Cistanches 9g, Herba Serissae 7g, Caulis Akebiae 4g, Bulbus Allii Fistulosi 2.

The preparation method of Chinese medicine of the present invention is:

1) by Rhizoma Dioscoreae, Radix Rehmanniae, Radix Angelicae Sinensis, Rhizoma Dioscoreae Hypoglaucae, Herba Portulacae, Radix Glycyrrhizae, Radix Ardisiae Crispae, Herba Cistanches, Caulis Akebiae decontamination, be soaked in water to softening, pulling out slightly dries in the air when being suitable for inside and outside humidity, and section is dried or dried, for subsequent use;

2) by Herba Taraxaci, Herba Houttuyniae, Radix Achyranthis Bidentatae, Herba Lophatheri decontamination, clean, cutting, dries or dries, for subsequent use;

3) by Radix Astragali roguing root, dry, for subsequent use;

4) by Radix Gentianae, Herba Hedyotidis Diffusae, Herba Serissae, Bulbus Allii Fistulosi decontamination, clean, for subsequent use;

5) by Radix Salviae Miltiorrhizae decontamination, clean, section, dries, gets Radix Salviae Miltiorrhizae Tabellae and pour in pot, with surperficial micro-Jiao of the micro-stir-fry of slow fire, takes out, cools, for subsequent use;

6) by Rhizoma Atractylodis Macrocephalae decontamination, pull out after immersion, section, dries, gets Rhizoma Atractylodis Macrocephalae sheet and pour in pot, be faint yellow with the micro-stir-fry of slow fire to epidermis, and taking-up is for subsequent use;

7) by Rhizoma Atractylodis decontamination, clean, be dipped to seven, most probably thoroughly, pull out, section, dries, gets Rhizoma Atractylodis sheet and pour in pot, fries to surperficial micro-Jiao with high heat, takes out, cool, for subsequent use;

8) by step 1g ~ step 7 standby crude drug, pour in marmite, add the water of octuple amount, immersion 2g ~ 2.5 hour, add Fructus Lycii and Bulbus Allii Fistulosi decocted with high heat to boiling after 30 minutes, use slow fire instead and continue decoction 2 hours, get immersion, obtained described Chinese medicine decoction.

9) by the immersion of step 8 gained, with modern production process, carry out sterilizing, concentrated, dry, pulverize, sieve, tabletting, dissolved granule, capsule, the tablet of obtained described Chinese medicine.

Usage and consumption: consumption of being grown up, decoction is every day 1 dose, and early, evening, respectively once every secondary amounts was 250ml, within 20 days, is a course for the treatment of.Dissolved granule is wrap every day 2, and early, wrap evening each one, often bag specification is 125mg, within 20 days, is a course for the treatment of.Capsule is every day 4, early, evening each 2, every specification is 50mg, within 20 days, is a course for the treatment of.Tablet is every day 10, early, evening each 5, every sheet specification is 10mg, 20 days courses for the treatment of.

Embodiment 2

Rhizoma Dioscoreae 60g, Herba Taraxaci 55g, Radix Astragali 33g, Herba Hedyotidis Diffusae 55g, Herba Portulacae 52g, Radix Salviae Miltiorrhizae 33g, Radix Rehmanniae 33g, Fructus Lycii 19g, Rhizoma Atractylodis Macrocephalae 23g, Herba Houttuyniae 23g, Radix Angelicae Sinensis 18g, Radix Achyranthis Bidentatae 18g, Radix Ardisiae Crispae 16g, Rhizoma Dioscoreae Hypoglaucae 17g, Rhizoma Atractylodis 13g, Herba Lophatheri 13g, Radix Glycyrrhizae 16g, Radix Gentianae 13g, Herba Cistanches 12g, Herba Serissae 11g, Caulis Akebiae 7g, Bulbus Allii Fistulosi 2

The usage and dosage of the present embodiment is identical with embodiment 1.

Embodiment 3

Rhizoma Dioscoreae 45g, Herba Taraxaci 45g, Radix Astragali 28g, Herba Hedyotidis Diffusae 45g, Herba Portulacae 45g, Radix Salviae Miltiorrhizae 30g, Radix Rehmanniae 30g, Fructus Lycii 16g, Rhizoma Atractylodis Macrocephalae 20g, Herba Houttuyniae 20g, Radix Angelicae Sinensis 16g, Radix Achyranthis Bidentatae 16g, Radix Ardisiae Crispae 13g, Rhizoma Dioscoreae Hypoglaucae 15g, Rhizoma Atractylodis 11g, Herba Lophatheri 11g, Radix Glycyrrhizae 14g, Radix Gentianae 11g, Herba Cistanches 10g, Herba Serissae 9g, Caulis Akebiae 5g, Bulbus Allii Fistulosi 2.

The usage and dosage of the present embodiment is identical with embodiment 1.

Clinical data:

1, case selection:

Selection is diagnosed as the routine clinical observation of non-gonococcal urethritis patients 80, and patient is divided into two groups at random.Treatment group 40 example, wherein male 17 example, women 23 example, age 22g ~ 48 year old, 32.6 years old mean age, matched group 40 example, wherein male 16 example, women 24 example, age 19g ~ 45 year old, 31 years old mean age, two groups of qualifications and record of service are basically identical.

2, diagnostic criteria:

Medical history is 1 month g ~ 24 month, allusion quotation clinical manifestation is that urethra is scratchy, with different weight frequent micturition, urgent micturition, dysurea and urinate because of difficulty, urethral orifice has mucus purulent secretion, there is urethra projection, hyperemia, redness in severe patient, the complication of nongonococcal urethritis is prostatitis, epididymitis, seminal vesicle spermatitis and proctitis.The complication of women's chlamydia, ureaplasma urealyticum infection is pelvic inflammatory disease, cervicitis, endometritis, and secretions pollutes crissum can cause anal inflammation, proctitis.All have above symptom, urinate centrifugal sediment smear polymorphonuclear leukocyte >=15/high power field microscopy equal morning first, or urethral swab smear has and positive finds that urethral swab smear polymorphonuclear leukocyte >=5/oily mirror visual field microscopy is made a definite diagnosis, and take the present invention and treat.

3, Therapeutic Method:

Treatment group patient takes decoction of the present invention, every day 1 dose, and early, evening, respectively once every secondary amounts was 250ml, takes 20 days.The oral erythromycin enteric-coated tablet of matched group patient is grown up 0.75g ~ 2g on the one, point 3g ~ 4 time.

4, efficacy determination:

(1) fully recover: clinical symptom disappearance, urethral secretions cultivates chlamydia trachomatis, Ureaplasma urealyticum detects feminine gender.

(2) take a turn for the better: clinical symptom disappearance, urethral secretions cultivation chlamydia, Ureaplasma urealyticum are detected as weak feminine gender.

(3) invalid: clinical symptom relief, urethral secretions cultivates chlamydia, Ureaplasma urealyticum is detected as the weak positive.

5, therapeutic outcome:

Cure 27 examples in treatment group, take a turn for the better 12 examples, invalid 1 example, cure rate 67.5%, total effective rate 97.5%.

Cure 8 examples in matched group, take a turn for the better 11 examples, invalid 21 examples, cure rate 20%, total effective rate 47.5%.

Above result display, the cure rate for the treatment of group and total effective rate, apparently higher than matched group, through clinical verification, during taking the present invention, do not find any untoward reaction and toxic and side effects.

6, model case citing:

Case 1:

Zhang, female, 27 years old, the second half year in 2008, often there is frequent micturition in patient, and urethral orifice is with sharp, urethral secretions smear, and under the high power microscope visual field, polymorphonuclear leukocyte number is greater than 5, and gonococcus is cultivated and is negative.Pathogenic microorganism separation check result is Ureaplasma urealyticum is the weak positive, and tongue fur is white, complexion is dark, matt, thready and rapid pulse without strength, is diagnosed as non-gonococcal urethritis.Take a course for the treatment of of Chinese medicine of the present invention, symptom obviously alleviates, and continues to take 2 courses for the treatment of, recovery from illness, so far again without recurring.

Case 2:

Certain, male suddenly, 36 years old, chlamydia infection, in clinic, oral erythromycin in a large number, has hung Ceftriaxone and the normal saline in a week, starts symptom and alleviates to some extent, after drug withdrawal one week, the state of an illness was serious all the more, and urethral orifice is red and swollen and have purulent secretion, urethra is scratchy, and testis aches, weak, concurrent prostatitis, orchitis, premature ejaculation, face is dark yellow, red tongue, thick fur, is diagnosed as nongonococcal urethritis.Take Chinese medicine of the present invention, treat 4 recoveries from illness course for the treatment of, without recurrence.

Case 3:

Chen, female, 32 years old, existing 15 months of ureaplasma urealyticum infection, urgent micturition, urine retention, urethral orifice was red and swollen loose, and lower abdomen aches, and Hypomenorrhea, color is black dull, and leucorrhea has the blood streak and has bad smell, often with pain in the lumbar region.Repeatedly hang cephalo-type, azithromycin class medicine, bad during symptom fashion, recurrent exerbation, goes to again institute of traditional Chinese medicine to do Chinese medicine

10 treatments, though the state of an illness some alleviate, last or could not be effected a radical cure, and cause pelvic inflammatory disease, chronic cervicitis, be diagnosed as nongonococcal urethritis.The present invention has invigorating the liver and kidney, QI and blood regulating, blood circulation promoting and blood stasis dispelling, treating stranguria removing toxic substances, take the present invention treatment, treat 2 the course for the treatment of symptom alleviate, complexion is ruddy, and urine is unobstructed, the eumenorrhea.After continuing to take 2 courses for the treatment of, Ureaplasma urealyticum is negative, after take again recovery from illness course for the treatment of, do not recur so far.

Case 4:

Huang, female, 24 years old, sex partner was multiple, have contaminated intercourse history, be diagnosed as nongonococcal urethritis, urethral orifice is red and swollen, and urethra is scratchy, pudendum rectal tenesmus, insomnia, dreaminess, be afraid of cold, weak, cold perspiration, be diagnosed as irritability stasis, qi depression to blood stasis, YANG QI deficiency, control and answer depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, supplementing QI and nourishing YIN.Take the present invention to be almost recovered 2 courses for the treatment of, after consolidate again a course for the treatment of and thoroughly fully recover, without recurrence.

Comprehensively above-mentionedly can to draw, Chinese medicine of the present invention effectively can treat nongonococcal urethritis, (chronic) chlamydia trachomatis, (chronic) Ureaplasma urealyticum and complication, select medical material to meet a monarch and his subjects left side and make it reason, there is effect for the treatment of stranguria removing toxic substances, invigorating the spleen for eliminating dampness, blood circulation promoting and blood stasis dispelling, supplementing QI and nourishing YIN, good absorbing effect, evident in efficacy, the without any side effects and untoward reaction through clinical verification, is applicable to large-scale popularization application.

Claims

1. for preventing and treating a Chinese medicine for nongonococcal urethritis, it is characterized in that, raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are:

2. a kind of Chinese medicine for preventing and treating nongonococcal urethritis according to claim 1, it is characterized in that, raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are: Rhizoma Dioscoreae 40 parts ~ 50 parts, Herba Taraxaci 40 parts ~ 50 parts, the Radix Astragali 26 parts ~ 30 parts, Herba Hedyotidis Diffusae 40 parts ~ 50 parts, Herba Portulacae 40 parts ~ 48 parts, Radix Salviae Miltiorrhizae 28 parts ~ 32 parts, Radix Rehmanniae 28 parts ~ 32 parts, Fructus Lycii 15 parts ~ 18 parts, the Rhizoma Atractylodis Macrocephalae 18 parts ~ 22 parts, Herba Houttuyniae 18 parts ~ 22 parts, Radix Angelicae Sinensis 15 parts ~ 17 parts, Radix Achyranthis Bidentatae 15 parts ~ 17 parts, Radix Ardisiae Crispae 12 parts ~ 15 parts, Rhizoma Dioscoreae Hypoglaucae 14 parts ~ 16 parts, Rhizoma Atractylodis 10 parts ~ 12 parts, Herba Lophatheri 10 parts ~ 12 parts, 13 parts ~ 15 parts, Radix Glycyrrhizae, Radix Gentianae 10 parts ~ 12 parts, Herba Cistanches 10 parts ~ 11 parts, Herba Serissae 8 parts ~ 10 parts, Caulis Akebiae 5 parts ~ 6 parts, Bulbus Allii Fistulosi 2.

3. a kind of Chinese medicine for preventing and treating nongonococcal urethritis according to claim 1, is characterized in that, raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are:

4. a kind of Chinese medicine for preventing and treating nongonococcal urethritis according to claim 1, is characterized in that, raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are:

5. a kind of Chinese medicine for preventing and treating nongonococcal urethritis according to claim 1, is characterized in that, raw material composition and the parts by weight of making described Effective Component of Chinese Medicine are:

6. the Chinese medicine for the treatment of nongonococcal urethritis according to claim 1, is characterized in that, the medicament of described Chinese medicine is decoction, dissolved granule, capsule or tablet.

7. the Chinese medicine for the treatment of nongonococcal urethritis according to claims 1 to 6, is characterized in that, comprises following processing step:

(1) by Rhizoma Dioscoreae, Radix Rehmanniae, Radix Angelicae Sinensis, Rhizoma Dioscoreae Hypoglaucae, Herba Portulacae, Radix Glycyrrhizae, Radix Ardisiae Crispae, Herba Cistanches, Caulis Akebiae decontamination, be soaked in water to softening, pulling out slightly dries in the air when being suitable for inside and outside humidity, and section is dried or dried, for subsequent use; (2) by Herba Taraxaci, Herba Houttuyniae, Radix Achyranthis Bidentatae, Herba Lophatheri decontamination, clean, cutting, dries or dries, for subsequent use; (3) by Radix Astragali roguing root, dry, for subsequent use; (4) by Radix Gentianae, Herba Hedyotidis Diffusae, Herba Serissae, Bulbus Allii Fistulosi decontamination, clean, for subsequent use; (5) by Radix Salviae Miltiorrhizae decontamination, clean, section, dries, gets Radix Salviae Miltiorrhizae Tabellae and pour in pot, with surperficial micro-Jiao of the micro-stir-fry of slow fire, takes out, cools, for subsequent use; (6) by Rhizoma Atractylodis Macrocephalae decontamination, pull out after immersion, section, dries, gets Rhizoma Atractylodis Macrocephalae sheet and pour in pot, be faint yellow with the micro-stir-fry of slow fire to epidermis, and taking-up is for subsequent use; (7) by Rhizoma Atractylodis decontamination, clean, be dipped to seven, most probably thoroughly, pull out, section, dries, gets Rhizoma Atractylodis sheet and pour in pot, fries to surperficial micro-Jiao with high heat, takes out, cool, for subsequent use; (8) by step 1g ~ step 7 standby crude drug, pour in marmite, add the water of octuple amount, immersion 2g ~ 2.5 hour, add Fructus Lycii and Bulbus Allii Fistulosi decocted with high heat to boiling after 30 minutes, use slow fire instead and continue decoction 2 hours, get immersion, obtained described Chinese medicine decoction; (9) by the immersion of step 8 gained, carry out sterilizing, concentrated, dry, pulverize, sieve, tabletting, dissolved granule, capsule, the tablet of obtained described Chinese medicine.