CN104524464A - Traditional Chinese medicine preparation for treating hyperactivity and preparation method of traditional Chinese medicine preparation - Google Patents

Traditional Chinese medicine preparation for treating hyperactivity and preparation method of traditional Chinese medicine preparation Download PDF

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CN104524464A
CN104524464A CN201410838844.3A CN201410838844A CN104524464A CN 104524464 A CN104524464 A CN 104524464A CN 201410838844 A CN201410838844 A CN 201410838844A CN 104524464 A CN104524464 A CN 104524464A
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radix
chinese medicine
medicine preparation
liver
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陈淑娟
单晓英
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating hyperactivity. The traditional Chinese medicine preparation for treating hyperactivity disclosed by the invention is prepared from spina date seed, gastrodia elata, stiff silkworm, periostracum cicada, scorpio, white paeony root, radix ophiopogonis, asparagus fern, radix glehniae, poria with hostwood, dendrobe, curcuma aromatica, rhizoma acori graminei, tortoise plastron, concha haliotidis, raw oyster shell, teasel root, the bark of eucommia, the fruit of Chinese wolfberry, flatstem milkvetch seed, the seed of Chinese dodder, loranthus parasiticus and dogwood according to a certain weight ratio. The traditional Chinese medicine preparation disclosed by the invention has the effects of nourishing liver, calming heart, dispelling wind, carrying out spasmolysis, nourishing yin and calming nerves, and has the obvious treatment effect.

Description

A kind of Chinese medicine preparation for the treatment of hyperkinetic syndrome and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for the treatment of hyperkinetic syndrome, the invention still further relates to the preparation method of this Chinese medicine preparation.
Background technology
Hyperkinetic syndrome and hyperkinetic syndrome are a kind of common children's behavior abnormal problems, also known as Cerebral function slight maladjustment or minimal brain dysfunction syndrome or attention deficit hyperactivity disorder.The intelligence of this kind of infant is normal or normal, but study, behavior and emotion aspect defectiveness, show as compared with child of the same age, difficult concentrating, note of short duration, hyperactivity, emotion is inflammable, so that affects school grade.All keep on unpleasant terms with people in family and school, in daily life, make the head of a family and teacher feel difficulty.Foreign data report prevalence is about 5 ~ 10%.Domestic also to think that school age population sends out patient quite a lot of, and account for all pupils 1 ~ 10%, boy is many far beyond girl, sends out well 6 ~ 14 years old age, and it is more that preterm children suffers from this disease.Hyperkinetic syndrome not only affects the physical and mental health of child, sometimes aggressivity, destructive behavior is developed into, the harm of hyperkinetic syndrome disease is very serious, meeting having an impact all the life to child, cause learning difficulty, what have is even forced to suspension, occurs human communication difficulty, social adaptation declines, aggression etc.But the hyperkinetic syndrome symptom of some children does not cause the attention of the head of a family, and be mistaken as " naughty ", " not obedient ".Owing to delaying therapic opportunity, not only have impact on the school grade of child, more the physical and mental development of child is damaged, even have influence on adult.Therefore the problem of social concerns has been become in recent years.
Hyperkinetic syndrome is divided into slightly by its its order of severity, moderate, severe three class, and the definite pathogenic factor of primary disease is not yet determined, most scholar thinks poisoning and neural factors of inherited genetic factors, biochemical factor, nervous physiology factor, brain injury, food element etc.The endogenous cause of ill of primary disease when the traditional Chinese medical science thinks that natural endowment is not enough, as father and mother are in bad health, particularly how sick mother's pregnancy period is, causes children's ferritic weak, lacks of proper care after one's birth or other sickly hindered, and educate improper all can causing and fall ill.The traditional Chinese medical science is many to be analyzed from overall aspect, how because the reasons such as liver of suffering from a deficiency of the kidney is high, deficiency of both the heart and spleen, type of phlegm-heat attacking the heart cause.
The method of current western medical treatment primary disease is a lot, but great majority can only reach recent clinical effectiveness, and long-term effect is not good, and can not only recur, and long-term taking Western medicine, irreversible damage is all caused to the hepatic and renal function of children's, there is toxic and side effects in various degree.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of hyperkinetic syndrome, this Chinese medicine preparation has determined curative effect for hyperkinetic syndrome, cheap, safe ready, the little feature of side effect.
Inventor is in clinical treatment practice for many years, and according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula for the treatment of the Chinese medicine preparation of hyperkinetic syndrome repeatedly.
The effect of Chinese medicine of the present invention:
Wherein:
Semen Ziziphi Spinosae: be the dry mature seed of Rhamnaceae plant Ziziphi Spinosae Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H.F.Chou.Nature and flavor are put down, sweet, sour.GUIXIN, spleen, liver, gallbladder meridian.Effect: nourishing the liver, mind calming, calms the nerves, arresting sweating." Bencao Jingshu ": Semen Ziziphi Spinosae, real acid is flat, and core is then held concurrently sweet.Special tonifying liver gallbladder, is also amusing again.Ripe then fragrance, fragrance enters spleen, therefore can return spleen.Can courage be mended, therefore can warm gallbladder.The gas phase of mothers and sons is led to, therefore also main fidgets due to deficiency, vexatious insomnia.Its main trusted subordinate's cold and heat, pathogens agglomerating gas gathers, and painful limbs arthralgia chiefly caused by damp pathogen person, all insufficiency of the spleen disease by heresy, spleen governing limbs therefore also.Gallbladder be all dirty first of, 11 dirtyly all depend on gallbladder, and the vital essence of the five internal organs, all reports in spleen, therefore takes it for a long time, function settling five organs.
Rhizoma Gastrodiae: be the dry tuber of orchid Rhizoma Gastrodiae Gastrodia elata Blume..Nature and flavor: sweet are flat.Return Liver Channel.Effect: suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.Dizzy for having a headache, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.Pharmaceutical research shows, Rhizoma Gastrodiae has significantly calm and anticonvulsant action.Rhizoma Gastrodiae is sweet flat, specially enter Liver Channel, function endogenous wind stopping relieving convulsion, and Gan Run is not strong, acts on gentle, the panacea of endogenous wind for it, can be used for treating the liver-wind stirring up internally caused by the various cause of disease, and infantile convulsion is twitched, no matter cold and heat and asthenia and sthenia, and all can compatibility application.
Bombyx Batryticatus: the larva for Bombycidae insecticide silkworm Bombyx mori Linnaeus. 4 ~ 5 age infects (or artificial vaccination) muscardine Beauveria bassiana(Bals.) Vuillant and lethal larva dry body.Nature and flavor: salty, pungent are flat.Return liver, lung, stomach warp.Effect: expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Cure mainly: apoplectic aphasia, middle tuyere nose eye are oblique.Bombyx Batryticatus treatment infantile convulsion is twitched.Bombyx Batryticatus is salty pungent flat, enters liver, lung two warp, can endogenous wind stopping relieving convulsion, arresting convulsion of reducing phlegm again, therefore to infantile convulsion, epilepsy and to hold the hot person of expectorant under the arm particularly suitable.The person that controls high fever tic, can with Periostracum Cicadae, Ramulus Uncariae Cum Uncis, Flos Chrysanthemi with use.Bombyx Batryticatus controls acute infantile convulsion, and convulsion person is sent out in phlegm dyspnea, with compatibilities such as the same Scorpio of Bombyx Batryticatus, Rhizoma Gastrodiae, Cinnabaris, Calculus Bovis, Arisaema Cum Bile.
Periostracum Cicadae: exuviae shell when the larva for cicada Cryptotympana atrata Fabr. Cryptotympana pustulata Fabricius sprouts wings.Nature and flavor: sweet, cold.Return lung, Liver Channel.Effect: dispelling wind and heat pathogens, rash are antipruritic, improving acuity of vision and removing nebula, endogenous wind stopping relieving convulsion.This product a surname is loose to be sent out thoroughly, wind-dispelling heat-dissipating, and rash antipruritic can be used for treats measles, eczema etc.For diseases such as tetanus, infantile convulsion, night cry.Periostracum Cicadae can be dispelled exogenous wind, can cease endogenous wind and spasmolytic of calming the frightened again, occur tic of the limbs to tetanus, can join that Scorpio is equivalent to be used.
Scorpio: be the dry body of Buthidae animal Scorpio Buthus martensii Karsch.Nature and flavor: pungent, flat, poisonous.Return Liver Channel.Effect: endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.Scorpio master enters Liver Channel, can calm down liver-wind, again expel wind to dredge collateral, has good endogenous wind stopping relieving convulsion effect, can be used for the spasm tic that treatment a variety of causes causes, and by the high heat controlling acute infantile convulsion wind, normal being equal to Rhizoma Gastrodiae, Bombyx Batryticatus is used.
The Radix Paeoniae Alba: be the dry root of dicotyledon ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Nature and flavor: cool, picric acid, is slightly cold.Effect: easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving, yin fluid astringing receives antiperspirant.This product energy nourishing the liver blood, holding back liver-yin, subduing the hyperfunction of the liver sun, dispersing liver-energy, can delay again that contraction is anxious, relieve the pain pain, is the good medicine of the various pain for the treatment of Liver Channel." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " purgation of spleen excess heat, only abdomen pain, sealing rushes down, and receives adverse flow of liver-QI pain, takes good care of conscience spleen channel blood, relax through sending down the abnormal ascending QI, only irritability pain." " herbal classic " Radix Paeoniae, though respectively in vain not red, the two is master to some extent respectively.So seek and unravel silk it and cure mainly all diseases, one is that replenishing blood and nourishing liver spleen is Kidney-Yin, and receives and take the photograph the at random of temper, and throwing off restraint of irritability is horizontal, then the Radix Paeoniae Alba.
Radix Ophiopogonis: be the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf) Ophiopogon japonicus (Thunb.) Ker-Gawl..Nature and flavor: sweet, micro-hardship, to be slightly cold.GUIXIN, lung, stomach warp.Effect: reinforcing stomach reg fluid, nourishing lung-YIN, clear away heart-fire relieving restlessness.Radix Ophiopogonis can clear away heart-fire in yin nourishing, and relieving restlessness is calmed the nerves, and enters the heart-nutriment, fever aggravated at night with controlling warm febrile disease.
Radix Asparagi: be the dried root of liliaceous plant Radix Asparagi Asparagus cochinchinensis (Lour.) Merr..Nature and flavor: sweet, bitter, cold.Return lung, kidney channel.Effect: nourishing YIN to relieve dryness, lung heat clearing is promoted the production of body fluid.For dryness of the lung dry cough, pertussis expectorant sticks, dry throat and mouth, dryness of the intestine constipation.Radix Asparagi and Radix Ophiopogonis often use simultaneously, to strengthen nourishing lung-YIN, the effect of the relieving restlessness that clears away heart-fire.
Radix Glehniae: be the dry root of samphire glehnia littoralis Glehnia littoralis Fr. Schmidt ex Miq..Nature and flavor: sweet, micro-hardship, to be slightly cold.Return lung, kidney channel.Effect: nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.Thirsty for lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound.Research display: Radix Glehniae not only has the effect of antipyretic-antalgic, can also strengthen body immunity.
Poria cum Radix Pini: for Polyporaceae crouches the sclerotium of hole platymiscium Poria [(Poria cocos Schw.) Wolf].Nature and flavor: sweet, light flat.GUIXIN, spleen channel.Function: mind calming, calm the nerves, diuretic." property of medicine opinion ": main infantile convulsion, tranquilizing the mind, mends tired; Main acute pain in the epigastrium heavily fortified point is full, and small intestinal is unfavorable.
Herba Dendrobii: be orchid dendrobium loddigesii Rolfe Dendrobium loddigesii Rolfe., Herba Dendrobii oculati Dendrobium fimbriatum Hook. var. oculatum Hook., the fresh or dry stem of HERBA DENDROBII Dendrobium chrysanthum Wall., Herba Dendrobii Dendrobium candidum Wall. ex Lindl. or Dendrobium nobile Dendrobium nobile Lindl..Nature and flavor: be slightly cold; Sweet.Return stomach, kidney channel.Function: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision." explaining abstruseness of the canon of materia medica ": Herba Dendrobii, Gan Keyue spleen, salty energy kidney tonifying, therefore many merits are dirty in water and soil two.But gas is wide slow, without the merit that victory is played, ancients with this tea in generation, very clearly on diaphragm.
Radix Curcumae: be the dried root of zingiberaceous plant RADIX CURCUMAE Curcuma wenyujin Y. H. Chen et C. Ling, Rhizoma Curcumae Longae Curcuma longa L., Guangxi zedoary Curcuma kwangsiensis S. G. Lee et C. F. Liang or Rhizoma Curcumae Curcuma phaeocaulis Val..Nature and flavor: pungent, bitter, cold.Return liver, the heart, lung meridian.Effect: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, removing heat from blood removing blood stasis with potent drugs.Cure mainly: all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.The pungent loose hardship of this product is let out, heat clearing away cold in nature, can have one's ideas straightened out by heart fire-clearing upset-relieving.
Rhizoma Acori Graminei: be the dry rhizome of acorus gramineus araceae plant Acorus tatarinowii Schott.Nature and flavor are pungent, bitter, temperature.GUIXIN, stomach warp.Effect: removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Rhizoma Acori Graminei has anticonvulsant action, and the volatile oil of Rhizoma Acori Graminei has sedation of calming the nerves, and Rhizoma Acori Graminei decoct takes the secretion of energy facilitating digestion liquid orally." herbal classic ": " happy hole, tonifying five ZANG-organs, logical nine orifices, improve visual and auditory acuity, goes out speech for main anemofrigid-damp arthralgia, cough with dyspnea." " Chongqing hall random notes ": Rhizoma Acori Graminei, comfortable gas, the smooth mind, happy mood, beneficial will, panacea also.Removing summer-heat medicinal it, relying, it is dirty turbid and defend city wall to eliminate the phlegm, nourish medicinal it, so as to declaring the knot of thought and being proficient in the law of natural movement.
Carapax et Plastrum Testudinis: be sternite and the carapace of Testudinidae animal chinemys reevesii.Nature and flavor: salty, sweet, be slightly cold.Return liver, kidney, heart channel.Effect: nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, Gu through only collapsing, reinforcing the heart of nourishing blood.Carapax et Plastrum Testudinis contains several amino acids, protein, fat and calcium salt etc. containing bone gelatin, hydrolysate.Cure mainly hyperactivity of YANG due to deficiency of YIN, yin asthenia generating intrinsic heat, stirring-up of pathogenic wind in the interior resulting from deficiency.To suffer from a deficiency of the kidney the atrophic debility of bones, infantile metopism.Deficiency of YIN-blood, palpitation with fear, insomnia, forgetful.This product can nourish blood reinforcing the heart, can be used for insomnia forgetfulness.
Concha Haliotidis: be the shell of Bao Ke animal Haliotis diversicolor (sea at the bottom of light certainly) Haliotis diversicolor Reeve, haliotis discus hannai Ino (sea at the bottom of hair certainly) Haliotis discus hannai Ino, sheep Bao (sea certainly) Haliotis ovina Gmelin, haliotis ruber Haliotis ruber (Leach), ear Bao Haliotis asinina Linnaeus or white Bao Haliotis laevigata (Donovan).Nature and flavor: salty, cold.Return Liver Channel.Effect: suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving.Dizzy for having a headache, cataract, blurring of vision, optic atrohic blindness nyctalopia.This product important city sending down the abnormal ascending QI, can fall the lung qi of superinverse and relieving asthma, and can fall again the gastric qi of superinverse and preventing or arresting vomiting, be longer than tranquillizing and subduing liver-yang, fall clearly liver-fire, the treatment vertigo.
Concha Ostreae: be the shell of Ostreidae animal long Concha Ostreae Ostrea gigas Thunberg, Dalian Bay Concha Ostreae Ostrea talienwhanensis Grosse or Crassostrea rivularis Ostrea rivularis Gould etc.Nature and flavor: salty, be slightly cold.Return liver, gallbladder, kidney channel.Effect: suppressing the hyperactive liver and subsiding YANG, hard masses softening and resolving, convergence are astringent or styptic treatment for spontaneous sweating.
Radix Dipsaci: be the dry root of Dipsacaceae plant Radix Dipsaci Dipsacus asperoides C. Y. Cheng et T. M. Ai (or Dipsacus asper Wall).Nature and flavor: bitter, pungent, tepor.Return liver, kidney channel.Effect: invigorating the liver and kidney; Bone and muscle strengthening; Blood circulation regulating; Only metrorrhagia, all energy invigorating the liver and kidney of the Cortex Eucommiae and Radix Dipsaci, bone and muscle strengthening, Chang Xiangxu is use, but the double sexual impotence, frequent micturition etc. controlling insufficiency of kidney-YANG of the Cortex Eucommiae, and Radix Dipsaci can continue injured, for traumatic injury, bruise and fracture etc.Control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer swells.The sweet temperature of this product is supporing yang, pungent temperature cold expelling, and with controlling insufficiency of kidney-YANG, below element deficiency and cold, sexual impotence erectile problem, seminal emission lingering diarrhea, the diseases such as enuresis frequent micturition, have liver and kidney tonifying concurrently, strong bone strengthening, the merit of promoting blood circulation.
The Cortex Eucommiae: be the dry bark of the Eucommiaceae plant Cortex Eucommiae (Eucommia ulmoides Oliver).Nature and flavor: sweet, temperature.Return liver, kidney, stomach warp.Effect: liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, solid through antiabortive.Compendium of Material Medica: the Cortex Eucommiae, ancient prescription only knows nourishing kidney, and only Wang Haogu speech is Liver Channel edema caused by disorder of QI medicine, and profit liver is dry, and tonifying liver is empty, sends out former times people and does not send out also.Lid liver governing tendons, kidney governing bones, it is strong that kidney fills then bone, and liver is filled then muscle and is good for, and bends and stretches utilization, all belongs to muscle.
Fructus Lycii: be the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L..Nature and flavor: sweet, flat.Return liver, kidney channel.Effect: nourishing the liver and kidney, replenishing vital essence to improve eyesight.Cure mainly: caused by liver and kidney deficiency; Have a dizzy spell; Visual unclear; Soreness of the waist and knees; Impotence and seminal emission; Cough due to consumptive disease; To quench one's thirst taking fluids profusely.The sweet flat matter profit of this product, flat invigorating the liver and kidney, for the disease of the hepatic and renal YIN deficiency.
Semen Astragali Complanati: be the dry mature seed of leguminous plant astragatus complanatus Astragalus complanatus R.Brown..Nature and flavor: sweet, warm.Return liver, kidney channel.Effect: temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs, reducing urination, improving eyesight.For lumbago due to renal deficiency, seminal emission premature ejaculation, nebulousurine leukorrhagia, dribbling urination, dizzy blurred vision." Gu Shi cures mirror " cloud: this product " special the kidney invigorating of reinforcing YIN-essence controlling nocturnal emission with astringent drugs, merit." Semen Astragali Complanati benefit essence and random sun, YANG invigorating and not random body.
Semen Cuscutae: be the dry mature seed of dicotyledon scammonia section plant Semen Cuscutae Cuscuta chinensis Lam..Nature and flavor are sweet, warm.Return liver, kidney channel.Effect: nourishing the liver and kidney, controlling nocturnal emission with astringent drugs is with urine, antiabortive, improving eyesight, antidiarrheal.The waist knee joint muscles and bones being applicable to deficiency of the liver and kindey is ached, the diseases such as legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf and women's leukorrhagia, habitual abortion.Semen Cuscutae gets final product YANG invigorating, again can tonifying YIN, has temperature and not dry, and the feature of tonify without causing stagnation is the good medicine of flat invigorating the liver and kidney.Often join Fructus Lycii, Fructus Schisandrae Chinensis etc.
Herba Taxilli: be the dry stem and branch with leaf of Loranthaceae plant Herba Taxilli Taxillus chinensis (DC.) Danser.Nature and flavor: bitter, sweet, flat.Return liver, kidney channel.Effect: invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit, Herba Taxilli invigorating the liver and kidney, bone and muscle strengthening, the profit that nourishes blood muscle.
Fructus Corni: be the drying and ripening sarcocarp of Cornaceae plant Fructus Corni Cornus officinalis Sieb. et Zucc..Nature and flavor: sour, puckery, tepor.Return liver, kidney channel.Effect: liver and kidney tonifying, essence astringing and desertion stemming.Cure mainly and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding.Fructus Corni tepor is not dry, mends and not high, can flat nourishing YIN sun, supports the flourish muscle of marrow, by treating the liver kidney deficiency is commonly used.
Side's solution of the present invention is: Semen Ziziphi Spinosae nourishing the liver mind calming in side, to calm the nerves arresting sweating, Rhizoma Gastrodiae suppressing the hyperactive liver to relieve the wind syndrome, Bombyx Batryticatus expelling wind to relieve convulsion, Periostracum Cicadae endogenous wind stopping relieving convulsion, dispelling wind and heat pathogens, Scorpio endogenous wind stopping spasmolytic, analgesic, the Radix Paeoniae Alba is enriched blood easing the affected liver, suppressing the hyperactive liver pain relieving, above Six-element is monarch drug altogether, on the one hand Semen Ziziphi Spinosae can nourishing the liver mind calming, pacify the emotion of patient's excitement, the emotion of patient is made to be easy to control, Rhizoma Gastrodiae on the other hand, Bombyx Batryticatus, Periostracum Cicadae, Scorpios etc. all enter Liver Channel, there is the effect of suppressing the hyperactive liver to relieve the wind syndrome, be used for infantile convulsion, tic spasm, the third aspect Radix Paeoniae Alba is enriched blood easing the affected liver, nourishing the liver blood, hold back liver-yin, subduing the hyperfunction of the liver sun, from three aspects on the whole to the health of patient, emotion is nursed one's health, make the emotion of patient and attention are all controlled.Radix Ophiopogonis, Radix Asparagi nourishing lung-YIN, clear away heart-fire relieving restlessness, Radix Glehniae nourishing YIN and clearing away lung-heat, Poria cum Radix Pini's mind tranquilizing and the heart calming, Herba Dendrobii nourishing YIN and clearing away heat, Radix Curcumae regulating qi to disperse stagnation, heart fire-clearing upset-relieving, Rhizoma Acori Graminei is had one's ideas straightened out eliminating phlegm, refreshment Fructus Alpiniae Oxyphyllae, and above seven tastes are ministerial drug altogether, not only can assist a ruler in governing a country monarch drug nourishing the liver mind calming, expelling wind to relieve convulsion, and can nourishing YIN and clearing away lung-heat, refreshment Fructus Alpiniae Oxyphyllae, hold back liver-yin then can to clear away heart-fire relieving restlessness, adjust mentality, help Patients' rights oneself behavior and emotion.Carapax et Plastrum Testudinis nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, Concha Haliotidis, Concha Ostreae suppressing the hyperactive liver and subsiding YANG, Radix Dipsaci, Cortex Eucommiae liver and kidney tonifying, bone and muscle strengthening, Fructus Lycii, Semen Astragali Complanati, Semen Cuscutae nourishing the liver and kidney, replenishing vital essence to improve eyesight, Herba Taxilli, Fructus Corni liver and kidney tonifying, a few taste is adjuvant drug altogether above, both monarch can be coordinated, minister strengthens nourishing the liver mind calming, expelling wind to relieve convulsion, the effect of nourishing YIN for tranquillization, monarch can also be restricted, ministerial drug high strong, should not with the very strong medicine of active force for the health of child's undeveloped mature and internal organs, adjuvant drug can make mild the nursing one's health the health of patient of the efficacy of a drug, patient is recovered gradually.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has effect of nourishing the liver mind calming, expelling wind to relieve convulsion, nourishing YIN for tranquillization, effectively can treat hyperkinetic syndrome.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Semen Ziziphi Spinosae 15-25 part, Rhizoma Gastrodiae 7-17 part, Bombyx Batryticatus 5-15 part, Periostracum Cicadae 4-14 part, Scorpio 5-15 part, Radix Paeoniae Alba 10-20 part, Radix Ophiopogonis 10-20 part, Radix Asparagi 10-20 part, Radix Glehniae 13-23 part, Poria cum Radix Pini 10-20 part, Herba Dendrobii 10-20 part, Radix Curcumae 10-20 part, Rhizoma Acori Graminei 15-25 part, Carapax et Plastrum Testudinis 10-20 part, Concha Haliotidis 15-25 part, Concha Ostreae 15-25 part, Radix Dipsaci 15-25 part, Cortex Eucommiae 13-23 part, Fructus Lycii 13-23 part, Semen Astragali Complanati 10-20 part, Semen Cuscutae 13-23 part, Herba Taxilli 13-23 part, Fructus Corni 5-15 part.
Wherein be preferably: Semen Ziziphi Spinosae 20 parts, 12 parts, Rhizoma Gastrodiae, Bombyx Batryticatus 10 parts, Periostracum Cicadae 9 parts, Scorpio 10 parts, the Radix Paeoniae Alba 15 parts, Radix Ophiopogonis 15 parts, Radix Asparagi 15 parts, Radix Glehniae 18 parts, Poria cum Radix Pini 15 parts, Herba Dendrobii 15 parts, Radix Curcumae 15 parts, Rhizoma Acori Graminei 20 parts, Carapax et Plastrum Testudinis 15 parts, Concha Haliotidis 20 parts, Concha Ostreae 20 parts, Radix Dipsaci 20 parts, the Cortex Eucommiae 18 parts, Fructus Lycii 18 parts, Semen Astragali Complanati 15 parts, Semen Cuscutae 18 parts, Herba Taxilli 18 parts, Fructus Corni 10 parts.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, as pill, powder, tablet, oral liquid etc.Such as these crude drug pulverize mix homogeneously can be made powder to take after mixing it with water; Can decocting be used, obtain filtrate after filtration, add antiseptic and make oral liquid; Also directly decoction can be taken if desired.
The preferred preparation method of the present invention is granule, and its preparation method is as follows:
Step one: by weight proportion of the present invention, first becomes medicated bag by Semen Ziziphi Spinosae, Fructus Lycii, Semen Astragali Complanati, Semen Cuscutae, Fructus Corni bundle, is put in water and soaks about 45 minutes, filters, for subsequent use;
Step 2: by weight proportion of the present invention, by Carapax et Plastrum Testudinis, Concha Haliotidis, Concha Ostreae is put into after marmite adds step one immersion and is remained cold water, exceed the horizontal finger of powder 3 ~ 4, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, then Rhizoma Gastrodiae is added, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Asparagi, Radix Glehniae, Radix Curcumae, Rhizoma Acori Graminei, Radix Dipsaci, the Cortex Eucommiae is put into pot and is decocted about 45 minutes, finally add Herba Dendrobii, medicated bag in Herba Taxilli and the Poria cum Radix Pini bound up with gauze and step one, put into pot and continue decoction 30 minutes, filter, obtain filtrate, when filtrate is concentrated into about 75 DEG C, add 75% ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, the thick paste of relative density 1.13 ~ 1.20 under 60 DEG C of environment,
Step 3: by weight proportion of the present invention, by Bombyx Batryticatus, Periostracum Cicadae, Scorpio is air-dry is crushed to 200 mesh sieves, for subsequent use;
Step 4: step 3 gained fine powder adds in step 2 gained thick paste and is uniformly mixed, dry, be ground into fine powder, add appropriate Icing Sugar as diluent, ethanol as wetting agent and microcrystalline Cellulose as disintegrating agent, adopt dry granulation, make 10g/ bag, every bag of granule containing crude drug 5g.
Medicine of the present invention has effect of nourishing the liver mind calming, expelling wind to relieve convulsion, nourishing YIN for tranquillization, and determined curative effect, cheap, safe ready, side effect is little, the mode that this Chinese medicine preparation adopts treat can remove hyperkinetic syndrome in the heart of physiology and on injury that child is caused, reduce the injury that Western medicine causes children's torso, also mitigate family burden simultaneously, add up according to clinical 160 routine patient view, use medicine of the present invention the total effective rate course for the treatment of 85%, two the total effective rate course for the treatment of 95%.
Detailed description of the invention
Embodiment one, Semen Ziziphi Spinosae 15 parts, 7 parts, Rhizoma Gastrodiae, Bombyx Batryticatus 5 parts, Periostracum Cicadae 4 parts, Scorpio 5 parts, the Radix Paeoniae Alba 10 parts, Radix Ophiopogonis 10 parts, Radix Asparagi 10 parts, Radix Glehniae 13 parts, Poria cum Radix Pini 10 parts, Herba Dendrobii 10 parts, Radix Curcumae 10 parts, Rhizoma Acori Graminei 15 parts, Carapax et Plastrum Testudinis 10 parts, Concha Haliotidis 15 parts, Concha Ostreae 15 parts, Radix Dipsaci 15 parts, the Cortex Eucommiae 13 parts, Fructus Lycii 13 parts, Semen Astragali Complanati 10 parts, Semen Cuscutae 13 parts, Herba Taxilli 13 parts, Fructus Corni 5 parts.
Embodiment two, Semen Ziziphi Spinosae 20 parts, 12 parts, Rhizoma Gastrodiae, Bombyx Batryticatus 10 parts, Periostracum Cicadae 9 parts, Scorpio 10 parts, the Radix Paeoniae Alba 15 parts, Radix Ophiopogonis 15 parts, Radix Asparagi 15 parts, Radix Glehniae 18 parts, Poria cum Radix Pini 15 parts, Herba Dendrobii 15 parts, Radix Curcumae 15 parts, Rhizoma Acori Graminei 20 parts, Carapax et Plastrum Testudinis 15 parts, Concha Haliotidis 20 parts, Concha Ostreae 20 parts, Radix Dipsaci 20 parts, the Cortex Eucommiae 18 parts, Fructus Lycii 18 parts, Semen Astragali Complanati 15 parts, Semen Cuscutae 18 parts, Herba Taxilli 18 parts, Fructus Corni 10 parts.
Embodiment three, Semen Ziziphi Spinosae 25 parts, 17 parts, Rhizoma Gastrodiae, Bombyx Batryticatus 15 parts, Periostracum Cicadae 14 parts, Scorpio 15 parts, the Radix Paeoniae Alba 20 parts, Radix Ophiopogonis 20 parts, Radix Asparagi 20 parts, Radix Glehniae 23 parts, Poria cum Radix Pini 20 parts, Herba Dendrobii 20 parts, Radix Curcumae 20 parts, Rhizoma Acori Graminei 25 parts, Carapax et Plastrum Testudinis 20 parts, Concha Haliotidis 25 parts, Concha Ostreae 25 parts, Radix Dipsaci 25 parts, the Cortex Eucommiae 23 parts, Fructus Lycii 23 parts, Semen Astragali Complanati 20 parts, Semen Cuscutae 23 parts, Herba Taxilli 23 parts, Fructus Corni 15 parts.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Accept out-patient 320 example for medical treatment, patient be divided into observation group and matched group at random, wherein male 172 example, women 148 example, M-F 1.16:1, max age 16 years old, minimal ages 4 years old, the course of disease a few natural life-span to several not etc. every year.Every basic documents such as two groups of patient ages, sex, courses of disease are substantially identical, no significant difference (P > 0.05).
Two, diagnostic criteria
1, attention deficit disorder: show as absent minded, not lastingly, easily disperses, and listens to the teacher inwholwe-hearted, can not fulfil assignment on time, easily be divert one's attention by environmental stimuli;
2, hyperactivity: show as on classroom or operation time quietly do not descend the heart, seat does not stop twisting, or upper class hour did little trick, such as fingernail biting, cut rubber or gaze around, affect classroom discipline, brothers do not stop or disorderly punching unrest is hit;
3, impulsion is wilful: show as irascible temperament, hot-tempered, does things disorderly and unsystematic, has Impulsive, aggression, as can not be patience waited, disturbs other people movable, handles affairs and lack thinking, be regardless of the consequences, even destroy thing, fight;
4, behavior change: show as slow movement, operation can not complete for a long time, and emotion easily fluctuates, being happy and angry uncertainly.
Three, Therapeutic Method:
1, observation group is according to Medications Example two of the present invention, and the granule that preferred preparation method is made, and boiled water is taken after mixing it with water, every day 3 times, each one bag, within 20 days, is a course for the treatment of.
2, matched group is according to the Chinese medicine oral liquid for the treatment of hyperkinetic syndrome in CN 103301368 A, and twice daily, each one bottle 30 days is a course for the treatment of.
Four, efficacy assessment standard:
1, cure: upper class hour visual cognitive ability, emotion is more stable, and school grade reaches child's level of the same age substantially;
2, effective: action reduces, and the time of sitting quietly is longer, and attention is slightly concentrated, and school grade rises to some extent;
3, invalid: symptom also school grade has no significant change.
Five, observation group's result statistics
Matched group result is added up
Wherein: total effective rate=cure rate+improvement rate
Can find that observation group is apparently higher than matched group, illustrates thus by the treatment total effective rate contrasting two groups of patients, Chinese medicine of the present invention has good clinical effectiveness in treatment hyperkinetic syndrome, effectively can improve the cure rate for the treatment of, be worth promoting in clinical practice.
Model case and curative effect:
Case one, patient Zhang, man, 9 years old, upper sophomoric Zhang attends class and always feels uneasy, like chipping in, answer, start teacher and tell the head of a family, the head of a family thinks that child is naughty, child is absent minded recently, easily by external influence, temper also becomes impulsion, these symptoms are more and more obvious, family long band Zhang goes hospital's inquiring, result hospital diagnosis is hyperkinetic syndrome, the head of a family takes Western medicine to Zhang, and to find that Zhang sometimes starts drowsiness later, so drug withdrawal, after drug withdrawal 3 days, Zhang's disease relapse, just medical in here afterwards, adopt made preparation in the embodiment of the present invention two, and selected preparation method, after taking treatment a period of time, the state of an illness is taken a turn for the better, patient is longer to oneself interested thing visual cognitive ability time, and emotion is controlled, operation can complete on time, continue to take a course for the treatment of, patient's visual cognitive ability of upper class hour, emotion is more stable, school grade also improves gradually, there is no other uncomfortable phenomenons, recovery from illness.
Case two, patient Zhao, female, 11 years old, upper-class Zhao's school grade is bad at primary school, and the head of a family is very worried, determines to go hospital's inquiring, daughter Zhao that the head of a family introduces oneself is from little just very quiet, the discipline of attending class that teacher also reacts child is good, never naughty, learns exactly always not increase, look at child at ordinary times also very diligent, adult also can only worry, and child is large always can not criticize her, helpless the saying of the head of a family.The cognition assessment, span of attention and the various cognitive function such as distribution and IQ that have done 3 hours to daughter at hospital doctor are assessed.Assessment result shows: beautiful overall IQ is in normal range, but compared with age cohorts, the attention in cognition 4 processes of beautiful formation intelligence, planning department are at reduced levels; Note continuing function impaired.Zhao has problems in attention persistency, have impact on the collection of its knowledge information, store and analyze, thus show learning difficulty, the head of a family worries that the side effect of Western medicine is large, the Liver and kidney of child is had an impact, determine to adopt Chinese traditional treatment, just medical in here afterwards, adopt made preparation in the embodiment of the present invention two, and selected preparation method, after taking a course for the treatment of, carry out visual cognitive ability test, Zhao's visual cognitive ability state is obviously deducted a percentage, continue to take a course for the treatment of, teacher Zhao reflected that student's attention of upper class hour was deducted a percentage to some extent, cash more positive, in recent midterm examination, Zhao's raise marks is obvious, hospital is gone to check, attention continues function and gets a promotion, reach the level close with age cohorts.

Claims (4)

1. treat the Chinese medicine preparation of hyperkinetic syndrome for one kind, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Semen Ziziphi Spinosae 15-25 part, Rhizoma Gastrodiae 7-17 part, Bombyx Batryticatus 5-15 part, Periostracum Cicadae 4-14 part, Scorpio 5-15 part, Radix Paeoniae Alba 10-20 part, Radix Ophiopogonis 10-20 part, Radix Asparagi 10-20 part, Radix Glehniae 13-23 part, Poria cum Radix Pini 10-20 part, Herba Dendrobii 10-20 part, Radix Curcumae 10-20 part, Rhizoma Acori Graminei 15-25 part, Carapax et Plastrum Testudinis 10-20 part, Concha Haliotidis 15-25 part, Concha Ostreae 15-25 part, Radix Dipsaci 15-25 part, Cortex Eucommiae 13-23 part, Fructus Lycii 13-23 part, Semen Astragali Complanati 10-20 part, Semen Cuscutae 13-23 part, Herba Taxilli 13-23 part, Fructus Corni 5-15 part.
2. the Chinese medicine preparation for the treatment of hyperkinetic syndrome according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: Semen Ziziphi Spinosae 20 parts, 12 parts, Rhizoma Gastrodiae, Bombyx Batryticatus 10 parts, Periostracum Cicadae 9 parts, Scorpio 10 parts, the Radix Paeoniae Alba 15 parts, Radix Ophiopogonis 15 parts, Radix Asparagi 15 parts, Radix Glehniae 18 parts, Poria cum Radix Pini 15 parts, Herba Dendrobii 15 parts, Radix Curcumae 15 parts, Rhizoma Acori Graminei 20 parts, Carapax et Plastrum Testudinis 15 parts, Concha Haliotidis 20 parts, Concha Ostreae 20 parts, Radix Dipsaci 20 parts, the Cortex Eucommiae 18 parts, Fructus Lycii 18 parts, Semen Astragali Complanati 15 parts, Semen Cuscutae 18 parts, Herba Taxilli 18 parts, Fructus Corni 10 parts.
3. the Chinese medicine preparation for the treatment of hyperkinetic syndrome according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is granule.
4. treat a preparation method for the Chinese medicine preparation of hyperkinetic syndrome, it is characterized in that, preparation method is as follows: step one: by weight proportion of the present invention, first Semen Ziziphi Spinosae, Fructus Lycii, Semen Astragali Complanati, Semen Cuscutae, Fructus Corni bundle are become medicated bag, be put in water and soak about 45 minutes, filter, for subsequent use, step 2: by weight proportion of the present invention, by Carapax et Plastrum Testudinis, Concha Haliotidis, Concha Ostreae is put into after marmite adds step one immersion and is remained cold water, exceed the horizontal finger of powder 3 ~ 4, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, then Rhizoma Gastrodiae is added, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Asparagi, Radix Glehniae, Radix Curcumae, Rhizoma Acori Graminei, Radix Dipsaci, the Cortex Eucommiae is put into pot and is decocted about 45 minutes, finally add Herba Dendrobii, medicated bag in Herba Taxilli and the Poria cum Radix Pini bound up with gauze and step one, put into pot and continue decoction 30 minutes, filter, obtain filtrate, when filtrate is concentrated into about 75 DEG C, add 75% ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, the thick paste of relative density 1.13 ~ 1.20 under 60 DEG C of environment, step 3: by weight proportion of the present invention, by Bombyx Batryticatus, Periostracum Cicadae, Scorpio is air-dry is crushed to 200 mesh sieves, for subsequent use, step 4: step 3 gained fine powder adds in step 2 gained thick paste and is uniformly mixed, dry, be ground into fine powder, add appropriate Icing Sugar as diluent, ethanol as wetting agent and microcrystalline Cellulose as disintegrating agent, adopt dry granulation, make 10g/ bag, every bag of granule containing crude drug 5g.
CN201410838844.3A 2014-12-30 2014-12-30 Traditional Chinese medicine preparation for treating hyperactivity and preparation method of traditional Chinese medicine preparation Pending CN104524464A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770773A (en) * 2016-05-04 2016-07-20 徐芳 Traditional Chinese medicinal preparation for treating adult mild brain disturbance and preparation method of traditional Chinese medicinal preparation
CN106509886A (en) * 2016-10-13 2017-03-22 赤水市亿成生物科技有限公司 Preparation method of gastrodia elata composite nutrient powder
CN106806711A (en) * 2017-02-23 2017-06-09 山东和兴药业有限公司 It is a kind of to treat Chinese medicine composition of children's hyperkinetic syndrome and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1485088A (en) * 2003-08-27 2004-03-31 斌 黄 Cinese material medical preparation for curing children' hyperkinetic symptom and the preparation process thereof
CN1554426A (en) * 2003-12-29 2004-12-15 西安中医脑病医院 Oral medicine for treating child restless syndrome
CN1772252A (en) * 2004-11-08 2006-05-17 吴春霞 Making process of children's hyperkinesia treating capsule
CN1857579A (en) * 2006-03-10 2006-11-08 陈德林 Anshenjiannaocong granule and its compounding process

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1485088A (en) * 2003-08-27 2004-03-31 斌 黄 Cinese material medical preparation for curing children' hyperkinetic symptom and the preparation process thereof
CN1554426A (en) * 2003-12-29 2004-12-15 西安中医脑病医院 Oral medicine for treating child restless syndrome
CN1772252A (en) * 2004-11-08 2006-05-17 吴春霞 Making process of children's hyperkinesia treating capsule
CN1857579A (en) * 2006-03-10 2006-11-08 陈德林 Anshenjiannaocong granule and its compounding process

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
马丙祥等: "黄连温胆汤在小儿神经系统疾病中的临床应用", 《中医儿科杂志》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770773A (en) * 2016-05-04 2016-07-20 徐芳 Traditional Chinese medicinal preparation for treating adult mild brain disturbance and preparation method of traditional Chinese medicinal preparation
CN106509886A (en) * 2016-10-13 2017-03-22 赤水市亿成生物科技有限公司 Preparation method of gastrodia elata composite nutrient powder
CN106806711A (en) * 2017-02-23 2017-06-09 山东和兴药业有限公司 It is a kind of to treat Chinese medicine composition of children's hyperkinetic syndrome and preparation method thereof

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