CN105561192A - Cordyceps sinensis and fructus hippophae healthy medicinal liquor - Google Patents

Cordyceps sinensis and fructus hippophae healthy medicinal liquor Download PDF

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CN105561192A
CN105561192A CN201610019820.4A CN201610019820A CN105561192A CN 105561192 A CN105561192 A CN 105561192A CN 201610019820 A CN201610019820 A CN 201610019820A CN 105561192 A CN105561192 A CN 105561192A
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cordyceps
flos
fructus
health
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朱志梅
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Gansu Guobo Wine Co Ltd
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Gansu Guobo Wine Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • A61K36/03Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/066Clavicipitaceae
    • A61K36/068Cordyceps
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Abstract

The invention discloses cordyceps sinensis and fructus hippophae healthy medicinal liquor which is good in taste and beneficial to absorption by a human body. Cordyceps sinensis, fructus hippophae and ginseng flowers are used as main drugs for improving body immunity and promoting health and balance of the human body; aloe, seaweed, asparagus, common yam rhizome, radix polygoni multiflori, folium coicis and millet are used as auxiliary drugs for replenishing blood and qi and promoting qi circulation to remove depression; grapefruits, grapes, curcumae flowers and roses are used for invigorating the heart and spleen and nourishing blood for tranquilization; the drugs are processed and then soaked in raw stock liquor for 3 months, then the container is opened, and the liquor can be drunk after being filtered.

Description

Cordyceps health-care hippophae rhamnoide medicated wine
Technical field
The present invention relates to field of health care products, particularly relate to the Cordyceps health-care hippophae rhamnoide medicated wine of conditioning subhealthy state.
Background technology
Subhealth state refers to the quickening along with modern society's rhythm of life, especially the sub-health state that some offices white collar men and women faces increases the weight of day by day, life stress is large, do not get enough athletic exercise, body aspect can show as that fatigue and weak, muscle and joint aches, dizzy headache, cardiopalmus are uncomfortable in chest, sleep disordered, inappetence, gastral cavity abdomen discomfort, loose stool constipation, sexual hypofunction, be afraid of cold that To Be Protected from Heat, be easy to catch a cold, eye is dry and astringent; Psychological aspects can show be in a bad mood low, upset, lather, being irritable and getting angry easily, fear is timid, hypomnesis, attention can not be concentrated, deficient in energy, bradykinesia etc.; Social communication aspect can show can not bear corresponding social role preferably, and work, learning difficulty, can not normally handle inter personal contact, family relation well, be difficult to carry out normal social communication etc., health is in sub-health state for a long time.
Subhealth state is a kind of critical state, is in the people of sub-health state, although do not have clear and definite disease, occurs the decline of mental energy and adaptive capacity, if this state can not be corrected timely, is very easy to cause psychosomatic disease.Namely subhealth state refers to non-sick unhealthy status, and this is the inferior health status of a class, is the state between boundary's Health and Disease, therefore has again the appellation of " secondary health ", " third state ", " intermediateness ", " state of vacillating ", " gray states " etc.World Health Organization (WHO) by body without organic disease, but have the state of some changing functions to be called " third state ", China is called " sub-health state ".
Namely the theory of " equilibrium between yin and yang healthy " in theory of Chinese medical science, for the medical treatment of sub-health state specifies direction.Face card to accomplish " sincerely examine the place of negative and positive and adjust it, scheduling to last with flat " (" Plain Questions the most pure virginity will be discussed greatly "), ought to better effects be received.
Do not have the medicine of effective conditioning subhealthy state at present, the people being in sub-health state can not indulge in excessive drinking, and as the saying goes that wine is that grain is made, and wine is grain essence, drinks 2-3 little cup every day useful and harmless to health.
Wine of the prior art is various in style, and have functional wine, carbonic acid wine etc., key consumer is teenager, and long-term drink can injure taste, causes rubbish in human body to increase, and brings hidden danger to health.Mouthfeel that so far there are no is good, the health promoting wine that the applicable weakness of the spleen and stomach while of nutritious again, the women of vim and vigour deficiency and common middle-aged and elderly people are drunk.
Summary of the invention
In view of this, technical problem to be solved by this invention is: provide the health promoting wine that a kind of mouthfeel is good, be conducive to again absorption of human body.
Improve body immunity with Cordyceps, Fructus Hippophae, Flos Ginseng for principal agent, promote health balance; With Aloe, Sargassum, Germinatus Phragmitis, Rhizoma Dioscoreae, Radix Polygoni Multiflori, Folium Coicis, Semen setariae blood-enriching qi-invigorating, promoting QI circulation for relieving depression for accessory drugs; With Fructus Citri grandis, Fructus Vitis viniferae, Flos Radix Curcumae, Flos Rosae Rugosae invigorating the heart and spleen, nourishing blood to tranquillize the mind; Above medicine is immersed in unlatching in 3 months in original plasm wine after treatment and filters drinkable.
Cordyceps health-care hippophae rhamnoide medicated wine is made up of the raw material of following weight proportion:
Contain in every 1000 parts of original plasm wines: Cordyceps 40-50 part, Fructus Hippophae 40-50 part, Flos Ginseng 1-10 part, Aloe 1-10 part, Sargassum 1-10 part, Germinatus Phragmitis 1-10 part, Rhizoma Dioscoreae 1-10 part, Radix Polygoni Multiflori 1-10 part, Folium Coicis 1-10 part, Semen setariae 1-10 part, Fructus Citri grandis 10-20 part, Fructus Vitis viniferae 10-20 part, Flos Radix Curcumae 10-20 part, Flos Rosae Rugosae 10-20 part.
As preferably, described original plasm wine is the wine selecting fermentation, and the number of degrees are 50 degree of-60 degree.
As preferably, described Cordyceps selects Cordyceps.
Cordyceps health-care hippophae rhamnoide medicated wine is made up of the raw material of following weight proportion:
Contain in every 1000 parts of original plasm wines: Cordyceps 45 parts, Fructus Hippophae 45 parts, Flos Ginseng 5 parts, Aloe 5 parts, Sargassum 5 parts, Germinatus Phragmitis 5 parts, Rhizoma Dioscoreae 5 parts, Radix Polygoni Multiflori 5 parts, Folium Coicis 5 parts, Semen setariae 5 parts, Fructus Citri grandis 15 parts, Fructus Vitis viniferae 15 parts, Flos Radix Curcumae 15 parts, Flos Rosae Rugosae 15 parts.
Its preparation method:
Step 1: Cordyceps, Fructus Hippophae, Flos Ginseng, Aloe, Sargassum, Germinatus Phragmitis, Rhizoma Dioscoreae, Radix Polygoni Multiflori, Folium Coicis, Flos Radix Curcumae, Flos Rosae Rugosae being picked clean post-drying by formula proportion, to be crushed to fine powder for subsequent use;
Step 2: by formula proportion Semen setariae picked clean after be placed on that to be crushed to fine powder after slow fire in iron pan fries out fragrance for subsequent use;
Step 3: step 1 and step 2 fine powder for subsequent use are contained in gauze sack and insert in original plasm wine, add Fructus Citri grandis and Fructus Vitis viniferae, imbeds ground lower seal and soaks 90 days, fully filter waste, leach supernatant and namely obtain medicated wine finished product after taking-up.
Usage and dosage: every day services once sooner or later, each 15ml.
Medicine pharmacology and the property of medicine as follows:
Cordyceps:
[nature and flavor] sweet in the mouth, property is put down.
[function] has the effect of nourishing YIN and moistening the lung, kidney invigorating and YANG supporting, so can adjust as nourishing the lung and kidney, hemostasis and phlegm, guarantor's lung, change dysentery, stop that consumptive disease is coughed etc. the food mended.Cordycep includes cordycepic acid.Vitamin B12, fat, albumen etc.Cordyceps property is sweet, Wen Ping, nontoxic, be famous strengthening by means of tonics medicine, conventional meat boiled dinner, has the effect that tonify deficiency is healthy and strong.Be applicable to treat caused spitting of blood such as insufficiency of lung-QI and deficiency of both the lung and kidney, pulmonary tuberculosis etc. or sputum mixed with blood, cough.Breathe hard, night sweat etc., also have good curative effect to impotence due to deficiency of the kidney, waist knee joint ache etc., the excellent tonic product of the person that is also oldaged physically weak.
Fructus Hippophae:
[another name] Da Er, Fructus Elaeagni Angustifoliae, fructus hippophae, large Er Buxing, vinegar willow, acid thorn, sour Liu Liu, it examines a day Cannes, acid thorn, black thorn, yellow acid thorn, acid are stung.
[nature and flavor] sour in the mouth; Puckery; Warm in nature
[effect] relieving cough and resolving phlegm; Invigorating the stomach and promoting digestion; Promoting blood circulation to remove blood stasis.Main cough with copious phlegm; Pulmonary abscess; Dyspepsia; Abdominal pain due to retention of food; Stomachache; Intestinal is scorching; Amenorrhea; Traumatic injury congestive edema.
The nutritive value of Fructus Hippophae is very high, containing fat, protein, saccharide, salt and vitamin, and rich content.
Flos Ginseng:
[nature and flavor]: bitterness Hui Tian, have the pungent sweet taste of Radix Ginseng.
[function]: supplement vitality of human body, regain one's strength, strengthens body immunity.
Aloe: the Pharmacopoeia of the People's Republic of China (version one in 2000) say in this way nature and flavor with return through: bitter, cold; Return liver, stomach, large intestine channel; Function with cure mainly: removing heat from the liver, relieving constipation; For constipation, infantile malnutrition, infantile convulsion; External treatment exudative dermatitis.Compendium of Material Medica says nature and flavor in this way: bitter, cold, nontoxic; Cure mainly: hot blast is unhappy, steam between septum pectorale, improving eyesight relieving palpitation, children epilepsy infantile convulsion, treat five kinds of child malnutrition, kill three worms and the sick skin ulcer fistula of hemorrhoid, separate Fructus Crotonis poison." China's book on Chinese herbal medicine " says that the health care of aloe is summarised as by " China's book on Chinese herbal medicine " of the great achievement of concentrating herbal medicine in this way: (1) let out down, namely relax bowel; (2) adjusting immunity of human body; (3) Kang Zhong ; (4) protection liver; (5) anti-gastric injury; (6) antibacterial; (7) repair tissue damage; (8) the protective effect to skin.Hardship, cold.Return liver, stomach, large intestine channel.Function with cure mainly: let out down, namely relax bowel; Adjusting immunity of human body; Kang Zhong ; Protection liver; Anti-gastric injury; Antibacterial; Repair tissue damage; To the protective effect of skin.
Sargassum:
[meridian distribution of property and flavor] is bitter, salty, cold.Return liver, stomach, kidney channel.
[function cures mainly] hard masses softening and resolving, expectorant, diuretic.For goiter, scrofula, painful and swollen testis, phlegm retention edema.Shennong's Herbal: " broken eliminating stagnation gas, carbuncle, the hard gas of carcinoma, abdomen stops lower ring, lower 12 edema for main thin tumor gas, core under neck." " Mingyi Bielu ": " and treat between skin and gather, cruelly routed, stay gas, accumulation of heat, diuresis " and " property of medicine opinion ": " treat hernia tenesmus, pain, core swells." " Treatise on Dietetic Therapy ": " led the cloudy gas of man, often eaten it, the man that disappears bursts disease.”
Germinatus Phragmitis:
[pharmacology value] 1, contribute to stabilizing blood pressure blood fat reducing; 2, contribute to suppressing cardiovascular disease; 3, contribute to prevention and anticancer; 4, contribute to control senile constipation, diuresis to recover from fatigue; 5, contribute to suppressing and resisting viral bacterium; 6, health invigorating allaying tiredness is contributed to.
[nutritive value] 1, homovitamin, high-cellulose, high protein 2, low sugar, low fat 3, a great number of elements containing multiple needed by human and trace element
[health-care effect] 1, cancer-resisting effect, can suppress topoisomerase active, directly kill cancerous cell, destruction of cancer cells telomerase, makes cancerous cell can not multiple fission and wither it, activates antioncogene adjustment signal, transfer cell growth normalization.2, to the therapeutical effect of cardiovascular disease, Germinatus Phragmitis can suppress hypertension, prevents sclerosis of blood vessels, reduces blood fat and cholesterol.3, on the impact of human immune system, Germinatus Phragmitis can reduce circulating immune complex CIC content, can produce thymosin, promotes the generation of T cell, thus improves immunologic function, immunity moderation mechanism.4, the effect in defying age can reduce the lipid peroxide of human organ, the content of LOP, improves the activity of superoxide dismutase SOD thus slow down aging.
Rhizoma Dioscoreae:
[nature and flavor] sweet in the mouth, property are flat, enter lung, spleen, kidney channel;
[function cures mainly] has strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will are calmed the nerves, effect of life lengthening; Cure mainly that weakness of the spleen and stomach, lassitude, inappetence, chronic diarrhea and dysentery, insufficiency of lung-QI are dry, phlegm dyspnea cough, kidney qi loss, soreness of the waist and knees, lower limb flaccidity be weak, the red disease such as swollen, fat of frequent micturition of quenching one's thirst, seminal emission premature ejaculation, leukorrhagia nebulousurine, skin.
Folium Coicis:
[collection] summer, autumn take.
[chemical composition] leaf is containing alkaloid.
[function cures mainly-Folium Coicis effect]
1. " Bencao Tujing ": for drinking perfume (or spice), beneficial hollow diaphragm.
2. " trifling record ": the summer-heat moon decocts drink, warming the stomach, replenishing QI and blood.
There is effect of warming spleen and stomach for dispelling cold, benefiting vital QI and blood, cure mainly cold syndrome of the stomach pain, the symptom of deficient qi and blood.
Radix Polygoni Multiflori:
[meridian distribution of property and flavor] is bitter, sweet, puckery, and temperature, returns liver, the heart, kidney channel.
[function cures mainly] detoxifies, eliminating carbuncle, loosening bowel to relieve constipation.For scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; Hyperlipidemia, has therapeutical effect to diseases such as neurasthenia, poliosis, alopecia, anemias, therefore, and delaying sanility, building body, health care heart.
Semen setariae:
[property is hidden] sweet salty, cool (old Semen setariae: bitter cold).
[return through]
(1) specially enter kidney, double enter spleen, stomach (" book on Chinese herbal medicine is looked for the truth ").
(2) enter that brothers are lunar, shaoyin channel (" book on Chinese herbal medicine brief points ").
[composition] every 100g Semen setariae is containing protein 9.7g, fatty 3.5g, saccharide 72.8g, hot 1515kJ, calcium 29mg, phosphorus 240mg, ferrum 4.7mg, carotene 0.19mg, vitaminB10 .57mg, vitamin B2 1.12nag, nicotinic acid 1.6mg, magnesium 93.1mg, copper 5.5mg, manganese 9.5mg, zinc 25mg, selenium 45mg, iodine 8mg and estrogen-like matters.
The protein of Semen setariae has glutelin, alcohol albumen, globulin etc. multiple.Seed-protein is containing the glutamic acid of volume, proline, alanine and methionine.
Deficient and the middle kidney tonifying of [function cures mainly] invigorating the spleen and regulating the stomach, tonification, except thermal detoxification.Control taste deficiency-heat, regurgitation is vomitted, quenches one's thirst, had loose bowels.Containing the multiple functional factor useful to property, energy tonifying YANG, YIN nourishing, aristogenesis in Semen setariae.
Fructus Citri grandis:
The acid of Fructus Citri grandis sweet in the mouth, cool in nature, there is activating QI to eliminate phlegm, lung moistening bowel relieving, effects such as spleen invigorating of enriching blood, the diseases such as lack of appetite, tastelessness, dyspepsia can be controlled, can help digest, expectorant is quenched the thirst, eliminating stagnation of regulating the flow of vital energy.
Medical value
Pomelo fragrant, sour-sweet, Liang Run, nutritious, medical value is very high, is one of famous and precious fruit of people's eating.The traditional Chinese medical science is thought, grapefruit flesh is cold in nature, sweet in the mouth, acid, has relieving cough and asthma, removing heat-phlegm, strengthening the spleen to promote digestion, a medical function of relieving restlessness of relieving the effect of alcohol; Pericarpium Citri grandis has another name called Exocarpium Citri Rubrum, and wide Exocarpium Citri Rubrum is warm in nature, bitter in the mouth, pungent, has the effect of activating QI to eliminate phlegm, strengthening the spleen to promote digestion, cold expelling dampness; Fructus Citri grandis is the seed of Fructus Citri grandis, containing obacunone, obakulactone, deacetylnomilin etc., and another fatty oil, inorganic salt, protein, crude fibre etc.Effect is similar to Semen Citri Reticulatae, cures mainly hernia; Folium Citri grandis, containing volatile oil, has the effects such as antiinflammatory, analgesia, dampness removing.Modern medicine and pharmacology research finds, containing compositions such as very abundant vitamin C and para-insulins in Fructus Citri grandis meat, therefore has blood sugar lowering, blood fat reducing, fat-reducing, skin Caring to support the effects such as appearance.Often edible, there is auxiliary therapeutic action to diseases such as hypertension, diabetes, sclerosis of blood vessels, overweight people is healthy and strong beautifying function.Fructus Citri grandis also has stomach invigorating, lung moistening, enriches blood, bowel relieving, the effect such as convenient, wound healing can be promoted, have good auxiliary curative effect to septicemia etc.In addition, Fructus Citri grandis contains biological active substances skin glycoside, can reduce the viscosity of blood.And fresh Fructus Citri grandis meat is due to the composition containing similar insulin, the ultimate food of diabetics especially.
Fructus Vitis viniferae:
The micro-acid of [nature and flavor] sweet in the mouth, property are put down,
[function] has invigorating the liver and kidney, replenishing QI and blood, appetizing are promoted the production of body fluid, effect of diuresis.Modern medicine study shows, Fructus Vitis viniferae also has anti-cancer, anticancer effect.
Flos Radix Curcumae:
[meridian distribution of property and flavor] is pungent, bitter, cold; GUIXIN, lung, Liver Channel.
[effect] promoting blood circulation and stopping pain, dispersing the stagnated live-QI to relieve the stagnation of QI, removing heat from blood clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.
Flos Rosae Rugosae:
[meridian distribution of property and flavor] sweet, micro-hardship, temperature.Return liver, spleen channel.
[function cures mainly] promoting QI circulation for relieving depression, and blood, pain relieving.For stomachache due to hyperactive liver-QI attacking the stomach, lack of appetite vomiting and nausea, menoxenia, falls and flutters the pain of injury.
Detailed description of the invention
Embodiment 1, formula:
Contain in every 1000g original plasm wine: Cordyceps 40g, Fructus Hippophae 40g, Flos Ginseng 1g, Aloe 1g, Sargassum 1g, Germinatus Phragmitis 1g, Rhizoma Dioscoreae 1g, Radix Polygoni Multiflori 1g, Folium Coicis 1g, Semen setariae 1g, Fructus Citri grandis 10g, Fructus Vitis viniferae 10g, Flos Radix Curcumae 10g, Flos Rosae Rugosae 10g.
Its preparation method:
Step 1: Cordyceps, Fructus Hippophae, Flos Ginseng, Aloe, Sargassum, Germinatus Phragmitis, Rhizoma Dioscoreae, Radix Polygoni Multiflori, Folium Coicis, Flos Radix Curcumae, Flos Rosae Rugosae being picked clean post-drying by formula proportion, to be crushed to fine powder for subsequent use;
Step 2: by formula proportion Semen setariae picked clean after be placed on that to be crushed to fine powder after slow fire in iron pan fries out fragrance for subsequent use;
Step 3: step 1 and step 2 fine powder for subsequent use are contained in gauze sack and insert in original plasm wine, add Fructus Citri grandis and Fructus Vitis viniferae, imbeds ground lower seal and soaks 90 days, fully filter waste, leach supernatant and namely obtain medicated wine finished product after taking-up.
Usage and dosage: every day services once sooner or later, each 15ml.
Embodiment 2, formula:
Contain in every 1000g original plasm wine: Cordyceps 45g, Fructus Hippophae 45g, Flos Ginseng 5g, Aloe 5g, Sargassum 5g, Germinatus Phragmitis 5g, Rhizoma Dioscoreae 5g, Radix Polygoni Multiflori 5g, Folium Coicis 5g, Semen setariae 5g, Fructus Citri grandis 15g, Fructus Vitis viniferae 15g, Flos Radix Curcumae 15g, Flos Rosae Rugosae 15g.
Preparation method is identical with embodiment 1 with usage and dosage.
Embodiment 3, formula:
Contain in every 1000g original plasm wine: Cordyceps 50g, Fructus Hippophae 50g, Flos Ginseng 10g, Aloe 10g, Sargassum 10g, Germinatus Phragmitis 10g, Rhizoma Dioscoreae 10g, Radix Polygoni Multiflori 10g, Folium Coicis 10g, Semen setariae 10g, Fructus Citri grandis 20g, Fructus Vitis viniferae 20g, Flos Radix Curcumae 20g, Flos Rosae Rugosae 20g.
Preparation method is identical with embodiment 1 with usage and dosage.
Medicated wine of the present invention carries out drug regimen in conjunction with modern Chinese medicine theory, each efficacy of drugs is made to produce coordinative role, thus reach there is relaxing muscles and tendons to promote blood circulation, spleen invigorating, blood fat reducing, remove interior free yl, the cancer-preventing health function of improving eyesight, and, each raw material is by cooperatively interacting and promoting, the raw material useful to human body and effect improve greatly, will good twice relative to the simple effect adopting single raw material to reach, simultaneously, by the interaction between above-mentioned each raw material, make its character gentleer, very be beneficial to absorption of human body, long-term drink also can not have side effects.Further, after each raw material is combined together by above-mentioned weight proportion, each raw-material taste merges cleverly, and the fragrant taste of flowers and fruits of Flos Radix Curcumae, Flos Rosae Rugosae, Fructus Citri grandis, Fructus Vitis viniferae brings out the best in each other, and mouthfeel is pure and fresh, moist, fragrant alcohol.After above-mentioned each combination of raw materials, long-term drink can also play blood circulation promoting and blood stasis dispelling, the function of QI invigorating brain-strengthening, black hair, Anti-hair loss, skin care, intestinal tract cleaning inflammation and harmful bacteria.
Pharmacology pharmacodynamic is tested:
1, acute toxicity test
Application mice carries out acute toxicity testing and shows: Mouse oral gavage medicated wine of the present invention, under 488.8g crude drug/kg dosage, after administration, mice occurs that light activity reduces, 1 hours recovers normal, Continuous Observation 7 days after administration, none animal dead, its overall health of patients, diet, take the photograph water, urine and body weight increase all normal;
Experimental result shows: the maximum dosage-feeding of Mouse oral gavage medicated wine of the present invention is 488.8g crude drug/kg/d (LD50 > 488.8g medicine/kg).
Medicated wine clinical application every day total amount of the present invention is 0.1g medicine/kg/d; By weighing machine, the dosis tolerata of mouse stomach medicated wine of the present invention is 4888 times of clinical patient.Point out this medicine acute toxicity low, clinical drug safety.
2, long term toxicity test
Select SD rat, give the medicated wine of the present invention of variable concentrations (18.0,6.0,2.0g medicine/kg), every day gavage once, continuous 90 days, within after last administration 24 hours, respectively group is alive kills 1/2 animal (male and female half and half), and all the other 1/2 animals continue observations 2 weeks rear living and kill.Duration of test observes outward appearance, general behavior, food ration, the body weight change of animal, within after administration 90 days, within 2 weeks, carries out the index checking such as hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crea, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology with drug withdrawal.
Result of the test shows: invention formulation is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and matched group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range, without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, rat is had no significant effect in high, medium and low three dosage (18.0,6.0,2.0g crude drug/kg) administration in continuous 90 days according to result of the test Chinese medicine preparation of the present invention, without clear and definite toxicity target organ and sensitive indicator, convalescent period observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention higher.
3, animal local excitation test:
Medicated wine of the present invention is to allergic reaction on guinea pigs and Rat-rectum medication irritation test.
Result shows: skin anaphylactic test, high dose group 0.8g (medicine)/kg, low dose group 0.1g (medicine)/kg, be equivalent to 20 times, 2.5 times that intend clinical people's consumption [0.04g (medicine)/kg] respectively, through percutaneous drug delivery, be showed no animal and produce allergy; Rectal application irritation test high dose group 5.0g (medicine)/kg, low dose group 3.2g (medicine)/kg, be equivalent to 125,80 times that intend clinical people's consumption respectively, mucous membrane of rectum is observed all without phenomenons such as hyperemia, edema in official hour, histopathologic examination compares no significant difference with blank group, have no and occur obvious irritative response, often organize its overall health of patients of Some Animals of retention, body weight, breathing, circulation, central nervous system and extremity are movable, equal Non Apparent Abnormality reaction
Effect and curative effect:
The present invention is directed to feature and the pathogeny of " subhealth state " patient, explore with great concentration and study intensively.Finally succeed in developing Cordyceps health-care hippophae rhamnoide medicated wine, meet the theory of Chinese medicine.This medicated wine is based on " calming heart and tranquilizing mind " " invigorating the kidney and spleen ", " relaxing muscles and tendons and activating QI and blood in the collateral ", ten hundreds of " subhealth state " patient of rehabilitation for many years, this medicated wine comprehensive therapeutic effect greatly exceed the Therapeutic mode that traditional Western medicine maintains, controls, avoid various drawback and toxic and side effects that Western medicine brings to patient, really from have adjusted patient body at all.

Claims (4)

1. Cordyceps health-care hippophae rhamnoide medicated wine, is characterized in that: be made up of the raw material of following weight portion:
Contain in every 1000 parts of original plasm wines: Cordyceps 40-50 part, Fructus Hippophae 40-50 part, Flos Ginseng 1-10 part, Aloe 1-10 part, Sargassum 1-10 part, Germinatus Phragmitis 1-10 part, Rhizoma Dioscoreae 1-10 part, Radix Polygoni Multiflori 1-10 part, Folium Coicis 1-10 part, Semen setariae 1-10 part, Fructus Citri grandis 10-20 part, Fructus Vitis viniferae 10-20 part, Flos Radix Curcumae 10-20 part, Flos Rosae Rugosae 10-20 part;
Its preparation method:
Step 1: Cordyceps, Fructus Hippophae, Flos Ginseng, Aloe, Sargassum, Germinatus Phragmitis, Rhizoma Dioscoreae, Radix Polygoni Multiflori, Folium Coicis, Flos Radix Curcumae, Flos Rosae Rugosae being picked clean post-drying by formula proportion, to be crushed to fine powder for subsequent use;
Step 2: by formula proportion Semen setariae picked clean after be placed on that to be crushed to fine powder after slow fire in iron pan fries out fragrance for subsequent use;
Step 3: step 1 and step 2 fine powder for subsequent use are contained in gauze sack and insert in original plasm wine, add Fructus Citri grandis and Fructus Vitis viniferae, imbeds ground lower seal and soaks 90 days, fully filter waste, leach supernatant and namely obtain medicated wine finished product after taking-up.
2. Cordyceps health-care hippophae rhamnoide medicated wine according to claim 1, is characterized in that: be made up of the raw material of following weight portion:
Contain in every 1000 parts of original plasm wines: Cordyceps 45 parts, Fructus Hippophae 45 parts, Flos Ginseng 5 parts, Aloe 5 parts, Sargassum 5 parts, Germinatus Phragmitis 5 parts, Rhizoma Dioscoreae 5 parts, Radix Polygoni Multiflori 5 parts, Folium Coicis 5 parts, Semen setariae 5 parts, Fructus Citri grandis 15 parts, Fructus Vitis viniferae 15 parts, Flos Radix Curcumae 15 parts, Flos Rosae Rugosae 15 parts.
3. the Cordyceps health-care hippophae rhamnoide medicated wine according to claim 1 and 2 any one, is characterized in that: original plasm wine is the wine selecting fermentation, and the number of degrees are 50 degree of-60 degree.
4. the Cordyceps health-care hippophae rhamnoide medicated wine according to claim 1 and 2 any one, is characterized in that: Cordyceps selects Cordyceps.
CN201610019820.4A 2016-01-13 2016-01-13 Cordyceps sinensis and fructus hippophae healthy medicinal liquor Pending CN105561192A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106544214A (en) * 2016-10-25 2017-03-29 青海珠峰冬虫夏草工程技术研究有限公司 A kind of Cordyceps gold dry red wine and preparation method thereof

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CN101597554A (en) * 2009-06-16 2009-12-09 赵宇 The thick wine of one kind of plant
CN103436407A (en) * 2013-08-27 2013-12-11 王辉 Preparation method of cordyceps sinensis wine
CN103468499A (en) * 2013-08-27 2013-12-25 王辉 Cordyceps sinensis health preservation wine
CN104651115A (en) * 2013-11-22 2015-05-27 青岛佳瑞庄园葡萄酒业有限公司 Grape wine having beautifying function

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101525569A (en) * 2008-03-03 2009-09-09 盛建洪 Body-building anti-aging health-care wine
CN101597554A (en) * 2009-06-16 2009-12-09 赵宇 The thick wine of one kind of plant
CN103436407A (en) * 2013-08-27 2013-12-11 王辉 Preparation method of cordyceps sinensis wine
CN103468499A (en) * 2013-08-27 2013-12-25 王辉 Cordyceps sinensis health preservation wine
CN104651115A (en) * 2013-11-22 2015-05-27 青岛佳瑞庄园葡萄酒业有限公司 Grape wine having beautifying function

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106544214A (en) * 2016-10-25 2017-03-29 青海珠峰冬虫夏草工程技术研究有限公司 A kind of Cordyceps gold dry red wine and preparation method thereof

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Application publication date: 20160511