CN105708970B - A kind of health food with function of blood sugar reduction - Google Patents

A kind of health food with function of blood sugar reduction Download PDF

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CN105708970B
CN105708970B CN201610068808.2A CN201610068808A CN105708970B CN 105708970 B CN105708970 B CN 105708970B CN 201610068808 A CN201610068808 A CN 201610068808A CN 105708970 B CN105708970 B CN 105708970B
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parts
health food
added
filtrate
solution
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CN105708970A (en
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兰进
陈向东
姚自奇
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Institute of Medicinal Plant Development of CAMS and PUMC
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Institute of Medicinal Plant Development of CAMS and PUMC
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Priority to CN201910900400.0A priority patent/CN110613134B/en
Priority to CN201610068808.2A priority patent/CN105708970B/en
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
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    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The present invention relates to a kind of health foods with function of blood sugar reduction, belong to food processing technology field.Its raw material of the health food includes dark green tea, Radix Angelicae Sinensis, Cortex Eucommiae, honeysuckle, ganoderma lucidum, fructus lycii, Radix Polygalae, odd Asia, elscholtiza, chrysanthemum, mulberry leaf, isomalto-oligosaccharide.The health food passes through selection raw material meticulously, and scientific composition not only has hypoglycemic health-care effect, also has beautifying face and moistering lotion, preventing hypertension, hyperlipidemia, anti-oxidant, anti-aging, improves the health-care effects such as immunity.

Description

A kind of health food with function of blood sugar reduction
Technical field
The present invention relates to a kind of health foods with function of blood sugar reduction, belong to food processing technology field.
Background technique
With the rapid development of economy, living standards of the people increase substantially, incident is that people suffer from hyperglycemia, height The probability of blood lipid also rapidly rises.In terms of health food, hypoglycemic, reducing blood lipid health food is increasingly by the happiness of people Love.Hyperlipidemia, high cholesterol, hypertension, hyperglycemia are all present epidemic diseases, and reducing blood lipid blood pressure lowering becomes a popular words Topic.According to statistics, there are about 1.5 hundred million diabetics, 80% is Non-Insulin Dependent Diabetes Mellitus, that is, type-2 diabetes mellitus in the whole world, Middle China has more than 4,000 ten thousand.Mainly there are chemicals and Chinese medicine to treat two kinds the treatment of diabetes at present, although chemistry now Drug is main drug application, but since Chinese medicine can also have good repair while hypoglycemic to pancreas islet, There is good prospect in treating diabetes.Due to diabetes all the life can not being cured property and drug resistance, drug resistance and drug The reasons such as side effect, this kind of crowd are very big to the demand of blood-sugar lowering type health-care food.Type-2 diabetes mellitus be also known as non-insulin according to Rely patients with type Ⅰ DM, hyperglycemia is its cardinal symptom, and control blood glucose can obviously improve the generation and development of complication.Existing market needs Seek a kind of health food of safe hypoglycemic that can be taken for a long time.
Summary of the invention
In order to solve the above technical problems, it is an object of that present invention to provide a kind of health foods with function of blood sugar reduction.It should By selecting raw material meticulously, scientific composition not only has hypoglycemic health-care effect, also has beautifying face and moistering lotion, in advance health food Anti- hypertension, anti-oxidant, anti-aging, improves the health-care effects such as immunity at hyperlipemia.
Realize that the object of the invention technical solution is as follows:
A kind of health food with function of blood sugar reduction, raw material include dark green tea, Radix Angelicae Sinensis, Cortex Eucommiae, honeysuckle, ganoderma lucidum, Chinese holly Matrimony vine, Radix Polygalae, odd Asia, elscholtiza, chrysanthemum, mulberry leaf, isomalto-oligosaccharide.
Preferably, the health food, in parts by weight, raw material include 10-200 parts of dark green tea, 1-10 parts of Radix Angelicae Sinensis, Cortex Eucommiae 5-50 parts, 10-200 parts of honeysuckle, 5-50 parts of ganoderma lucidum, 10-150 parts of fructus lycii, 5-20 parts of Radix Polygalae, odd 5-100 parts of Asia, elscholtiza 5- 50 parts, 10-200 parts of chrysanthemum, 5-100 parts of mulberry leaf, 0.1-1 parts of isomalto-oligosaccharide.
It is further preferred that the health food, in parts by weight, raw material include 50-150 parts of dark green tea, Radix Angelicae Sinensis 2-8 Part, 10-40 parts of Cortex Eucommiae, 50-150 parts of honeysuckle, 10-40 parts of ganoderma lucidum, 50-120 parts of fructus lycii, 10-15 parts of Radix Polygalae, surprise Asia 10- 80 parts, 10-40 parts of elscholtiza, 50-150 parts of chrysanthemum, 10-80 parts of mulberry leaf, 0.2-0.8 parts of isomalto-oligosaccharide.
Preferably, the health food, in parts by weight, raw material include 120 parts of dark green tea, 3 parts of Radix Angelicae Sinensis, 15 parts of Cortex Eucommiae, 70 parts of honeysuckle, 15 parts of ganoderma lucidum, 80 parts of fructus lycii, 12 parts of Radix Polygalae, 50 parts odd sub-, 30 parts of elscholtiza, 85 parts of chrysanthemum, 60 parts of mulberry leaf, 0.6 part of isomalto-oligosaccharide.
The parts by weight can be the unit of weight well known in the art such as μ g, mg, g, kg, be also possible to its multiple, and such as 1/ 10,1/100,10 times, 100 times etc..
The above-mentioned health food with function of blood sugar reduction, wherein dark green tea, Radix Angelicae Sinensis, Cortex Eucommiae, honeysuckle, ganoderma lucidum, fructus lycii, remote Will, odd Asia, elscholtiza, chrysanthemum, mulberry leaf, isomalto-oligosaccharide are as active raw materials；Preferably, its raw material of above-mentioned health food Or auxiliary material further includes acceptable carrier pharmaceutically or on food or on health food.
Preferably, the health food is formed into oral preparation；It include: capsule, granule, tablet, packed medicinal tea, powder Agent etc.；More preferably granule.
It is further preferred that its raw material of the health food or auxiliary material further include microcrystalline cellulose, magnesium stearate.
The present invention also provides the preparation methods of above-mentioned health food, method includes the following steps: weighing according to the proportion each Ingredient mixes, is prepared into preparation according to conventional preparation method.
Preferably, above-mentioned health food preparation method the following steps are included:
1) ingredient；It is (including dark green tea, Radix Angelicae Sinensis, Cortex Eucommiae, honeysuckle, ganoderma lucidum, fructus lycii, remote that required raw material is weighed according to the ratio Will, odd Asia, elscholtiza, chrysanthemum, mulberry leaf, isomalto-oligosaccharide etc.)；
2) after mixing Radix Angelicae Sinensis, Cortex Eucommiae, ganoderma lucidum, Radix Polygalae, odd sub-, elscholtiza, the 50%-90% ethyl alcohol of 5-10 times of weight is added to return Stream extracts 1-3 times, 0.5-3.0 hours each, and filtration, merging filtrate concentrates the filtrate to clear cream (relative density 1.10- 1.30,30 DEG C), ethyl alcohol, which is added, makes alcohol content up to 70%-75%, obtains solution I；
3) after mixing dark green tea, honeysuckle, fructus lycii, chrysanthemum, mulberry leaf, add water decoction 1-3 times of 5-15 times of weight, every time 0.5-2 hours, collecting decoction, filtration concentrated the filtrate to clear cream (relative density 1.10-1.30,30 DEG C), ethyl alcohol is added to make to contain Alcohol amount reaches 70%-75%, obtains solution II；
4) merge the solution I and solution II, stir evenly, stand, it is (relatively close to be concentrated into clear cream for filtration, filtrate recycling ethanol Spending is 1.10-1.30,30 DEG C)；Isomalto-oligosaccharide is added by formula and suitable dosage form is made in appropriate amount of auxiliary materials.Preferably, add Enter appropriate microcrystalline cellulose, magnesium stearate, granule is made.
Specifically, above-mentioned health food preparation method the following steps are included:
1) ingredient；It is (including dark green tea, Radix Angelicae Sinensis, Cortex Eucommiae, honeysuckle, ganoderma lucidum, fructus lycii, remote that required raw material is weighed according to the ratio Will, odd Asia, elscholtiza, chrysanthemum, mulberry leaf, isomalto-oligosaccharide etc.)；
2) it after mixing Radix Angelicae Sinensis, Cortex Eucommiae, ganoderma lucidum, Radix Polygalae, odd sub-, elscholtiza, is extracted 2 times with 70%-75% alcohol reflux, the 1 addition, 8 times of w ethanols extract 3h, and 6 times of w ethanols of the 2nd addition extract 1h, filtration, and filtrate is concentrated merging filtrate To clear cream (relative density 1.10-1.30,30 DEG C), ethyl alcohol, which is added, makes alcohol content up to 70%-75%, obtains solution I；
3) it after mixing dark green tea, honeysuckle, fructus lycii, chrysanthemum, mulberry leaf, adds water to cook 2 times, 10 times of weight of the 1st addition Water decocts 2h, and 8 times of w ethanols are added for the 2nd time and extract 1h, collecting decoction, filtration, and concentrating the filtrate to clear cream, (relative density is 1.10-1.30,30 DEG C), add ethyl alcohol to make alcohol content up to 70%-75%, obtain solution II；
4) merge the solution I and solution II, stir evenly, stand, it is (relatively close to be concentrated into clear cream for filtration, filtrate recycling ethanol Spending is 1.10-1.30,30 DEG C)；Isomalto-oligosaccharide is added by formula and suitable dosage form is made in appropriate amount of auxiliary materials；Preferably, add Enter appropriate microcrystalline cellulose, magnesium stearate, granule is made.
Unless otherwise specified, concentration of alcohol of the present invention refers both to volumetric concentration.
It is demonstrated experimentally that the present invention extracts traditional Chinese medicinal material raw materials using above-mentioned technique, Chinese medicine original is utmostly remained The effective ingredient of material, and the effective component extracted is easiest to be absorbed by the body, and enhances the absorption of drug, so as to avoid invalid Ingredient interferes the problem of drug effect.
Dark green tea (dark tea) because the appearance of made tea is in black, therefore gains the name, is one of six big teas, belongs to post-fermented tea. Caffeine, vitamin, amino acid, phosphatide in dark green tea etc. facilitate human consumption, adjust fat metabolism, and the stimulation of caffeine is made It is helped digest with the secretory volume that can more improve gastric juice to improve a poor appetite.Verification of Science is it was demonstrated that dark green tea has very strong solution It is greasy, the functions such as help digestion, this is also that carnivorous nationality misses potter the reason of this grows tea.In addition, dark green tea can also improve the micro- life of enteron aisle Substance environment has the function along stomach.China is civil to have the old dark green tea of utilization to treat abdominal distension, dysentery, the tradition of indigestion.Meanwhile More complicated flavonoids of catechin, theaflavin, theanine and tea polysaccharide, especially content in dark green tea etc. all have remove from By the function of base, thus has the function of anti-oxidant, delaying cell aging.
When the dry root for being classified as umbelliferae angelica Angelica sinensis (Oliv.) Diels, there is work of enriching blood The effect of blood, regulating menstruation and relieving pain, moistening intestines and relaxing bowels.It is usually used in blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, amenorrhea and algomenorrhea, cold of insufficiency type abdomen Bitterly, rheumatic arthralgia, injury from falling down, ulcer sores, dry constipation of intestines.Prepared RADIX ANGELICAE SINENSIS with yellow rice wine blood circulation.For amenorrhea and algomenorrhea, rheumatic arthralgia, Injury from falling down.
Cortex Eucommiae Eucommia ulmoides Oliver also known as bakelite are the dry bark of Eucommiaceae plant Cortex Eucommiae.Its taste It is sweet, it is warm-natured.Tonify the liver and kidney, strengthen muscles and bones, coordinating Chong and Conception Vessels, strengthen meridian and miscarriage prevention the effect of.Pain in waist and lower extremities caused by kidney-yang deficiency can be treated Or aching and limp inability, born of the same parents' tire caused by liver- qi invasion is not solid, the wet equal diseases of itching of scrotum.Top grade is listed in Shennong's Herbal.It is modern It studies Cortex Eucommiae and has and remove internal rubbish, reinforce human body cell metabolism, prevent muscle skeleton aging, balanced human's blood pressure, Decomposer inner cholesterol reduces body fat, restores blood vessel elasticity, diuresis heat-clearing, broad-spectrum antiseptic, stimulating central nervous system, raising White blood cell pharmacological action.
Honeysuckle is cold in nature, sweet in flavor, enters lung, the heart, stomach meridian, has effects that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treats wind, cures mainly swollen Completely descend disease, warm disease heating, the diseases such as heat toxin large carbuncle and tumour.It is for dizziness, thirst, sweating and boring, enteritis, bacterium Dysentery, morbilli, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, ecphyaditis, skin infection, ulcer boils, erysipelas, the parotid gland The illnesss such as inflammation, suppurative tonsillitis have certain curative effect.Honeysuckle can improve microcirculation, remove peroxidating fat deposition, promote Into metabolism；Cortex Eucommiae tonifying Qi and enhancement spleen function and metabolic capability are low.
Ganoderma lucidum has invigorating qi for tranquilization, relieving cough and asthma effect, is used for dizziness egersis, shortness of breath and palpitation, neurasthenia, consumptive disease cough Asthma, promotes longevity.Ganoderma lucidum has the function of promoting blood circulation, and can make the moderate phenomenon of the blood of some minute blood vessels, obtain It is significant to improve.Equally, ganoderma lucidum can also accelerate the blood circulation of some tiny blood vessels of face, obtain Skin Cell sufficiently Nutriment and oxygen, promote the metabolism of skin.
Fructus lycii property is sweet, flat, returns liver kidney channel, have it is nourishing liver and kidney, the effect of nourishing the liver to improve visual acuity.Modern medicine study proves: Chinese holly Qi have immunological regulation, anti-oxidant, anti-aging, antitumor, antifatigue, reducing blood lipid, hypoglycemic, blood pressure lowering, kidney tonifying, liver protection, improving eyesight, 16 Xiang Gongneng such as beauty treatment, brain tonic, toxin expelling, protection reproductive system, Antiradiation injury.In addition, whitening function can also be played, this is Because the ability that skin absorbs oxygen can be improved in fructus lycii.
Radix Polygalae Polygala tenuifolia Willd has the function of tranquilize the mind and promote the intelligence, eliminating the phlegm, detumescence, bitter in taste, pungent, Temperature.Channel tropism return heart, kidney, lung channel.Despicable for insomnia and dreamful sleep caused by breakdown of the normal physiological coordination between the heart and the kidney, amnesia and pavor, expectoration is not well, sore Ulcer pyogenic infections, breast swell and pain.
Odd Asia (Chia Seed) also known as odd refined son, odd sub- seed, scientific name chia (Salvia Hispanica L.), Pennyroyal, source area are the North America such as Mexico south and Guatemala area.It is of the present invention odd sub-, it is the plant Seed --- odd Asia seed.It is odd sub- it be and to contain natural rich in the most abundant food of omega-3 fatty acid.It removes Other than common anti-oxidizing elements (vitamin E, C and lecithin), contains richer natural in odd Asia seed, be Anti-ageing diseases prevention gives protection against cancer required: caffeic acid (caffeic acid) can be hardened with prevention of arterial；Chlorogenic acid (chlorogenic Acid) effectively inhibit canceration, and have antiobesity action；Other antioxidant such as oak doradexanthin (quercetin), Kaempferol It (kaempferol) etc. is also anti-cancer, anti-aging active principle.
Elscholtiza energy inducing sweat and dispelling exogenous evils, dampness elimination is in, inducing diuresis for removing edema.The major functions: the cold drink of summer month sense is cold, to have a headache and fever, aversion to cold is lossless, Feeling of stuffiness in chest abdominal pain, vomiting and diarrhoea, oedema, tinea pedis.Can sweating and inducing diaphoresis and dampness elimination and in and relieving summer-heat, moreover it is possible to open the inhibited lung-energy and Inducing diuresis for removing edema.For function like Chinese ephedra, the efficacy of a drug is also strong, controls that cold sensation of the genitalia closes heat and geomantic omen oedema is most suitable, therefore is known as the title of " summer month Chinese ephedra ".Control urgency The diseases such as property enterogastritis, abdominal pain vomits and diarrhoea, summer and autumn yang summer-heat syndrome, have a headache and fever, aversion to cold is lossless, cholera, oedema, nosebleed epistaxis, halitosis.
Chrysanthemum nature and flavor bitter, sweet, cold nature.Channel tropism return lung, Liver Channel.Effect relieve heat heat-clearing, calming the liver and improving eyesight are clearing heat and detoxicating. Chrysanthemum, which can be used as medicine, cures the disease, and long term usage or drink chrysanthemum tea can make us long-lived.Using anemopyretic cold, warm disease from the beginning of；Dizziness due to hyperactivity of liver-YANG, liver wind Real example；Red eyes and dim-sighted；Sore and toxic etc..
Mulberry leaf are the dried leafs of moraceae plants mulberry, nature and flavor bitter, sweet, cold in nature.Channel tropism return lung, Liver Channel.Effect dispelling wind and heat from the body, Clearing away the lungheat and moisturizing, calming the liver and improving eyesight, cooling blood and hemostasis.Cure mainly anemopyretic cold, warm disease is from the beginning of, cough with lung heat, liver-yang hyperactivity dizziness, hot eyes dusk Flower, the hemoptysis of blood-heat bleeding are spitted blood.
The present invention is guidance with Chinese Traditional Medicine theory, in conjunction with modern medicine study, is selected meticulously from health angle Raw material, scientific composition reach hypoglycemic health-care effect, in addition also have skin maintenance and cosmetic benefits, keep fit life, build up health, preventing Disease, the healthcare function promoted longevity.The present invention focuses on the whole conditioning of human body and inherent conditioning, develops in conjunction with health Health food not only there is hypoglycemic health-care effect, additionally it is possible to promote the good health and a long life of human body.
The principles of formulating prescriptions of the present invention: being monarch with dark green tea, fructus lycii, using ganoderma lucidum, Cortex Eucommiae, chrysanthemum as minister, with Radix Angelicae Sinensis, honeysuckle, Mulberry leaf are assistant, are to make with Radix Polygalae, odd Asia, elscholtiza, isomalto-oligosaccharide, to assist improving the hypoglycemic effect of product.All medicines close With the effect of playing relieving heat and thirst, nourishing Yin and promoting production of body fluid, nourishing Yin and moistening dryness altogether and have moistening lung, clearing stomach, nourshing kidney concurrently；And have qi and activate blood circulation, toxin expelling The effect of beauty treatment, can skin toner moisturizing, please pool face.Selected raw material of the present invention improves human five internal organs, and comprehensive function reaches drop of quenching one's thirst The health-care effect of sugar.Wherein keep the motive vigorous by improving heart, painstaking effort are full；Liver storing blood makes qi and blood by improving liver It is gentle；The spleen being the foundation of acquired constitution, source of generating QI and blood；By function of spleen and stomach regulating, make the strong fortune of its function, qi and blood is vigorous；Lung governing skin and hair leads to Crossing conditioning lung enables qi-blood-body fluid spreading whole body；Kidney controlling essence storage keeps kidney essense full by conditioning kidney, when kidney qi is vigorous, five Dirty function will also operate normally, and qi and blood is vigorous, body-building.
Health food of the present invention is a kind of to follow the fashion, again take into account in a manner of traditional product drink, to reach in satisfied It is beneficial to the purpose of person in middle and old age and sub-health population health care.Health food action temperature of the present invention and, efficacy stability is nontoxic secondary to make With suitable long-term drinking.The study found that taking health food of the present invention for a long time also has preventing hypertension, hyperlipemia, antioxygen Change, delay senescence, improve the health-care effects such as immunity.
Specific embodiment
The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..It is not specified in embodiment specific Technology or conditions person, described technology or conditions according to the literature in the art, or carried out according to product description.It is used Production firm person is not specified in reagent or instrument, is the conventional products that can be commercially available by regular distributor.
Embodiment 1
A kind of health food with function of blood sugar reduction, its raw material includes 10 parts of dark green tea, 1 part of Radix Angelicae Sinensis, Du in parts by weight Secondary 5 parts, 10 parts of honeysuckle, 5 parts of ganoderma lucidum, 10 parts of fructus lycii, 5 parts of Radix Polygalae, 5 parts odd sub-, 5 parts of elscholtiza, 10 parts of chrysanthemum, 5 parts of mulberry leaf, 0.1 part of isomalto-oligosaccharide.
Embodiment 2
A kind of health food with function of blood sugar reduction, in parts by weight its raw material include 200 parts of dark green tea, 10 parts of Radix Angelicae Sinensis, 50 parts of Cortex Eucommiae, 200 parts of honeysuckle, 50 parts of ganoderma lucidum, 150 parts of fructus lycii, 20 parts of Radix Polygalae, odd sub- 100 parts, 50 parts of elscholtiza, chrysanthemum 200 Part, 100 parts of mulberry leaf, 1 part of isomalto-oligosaccharide.
Embodiment 3
A kind of health food with function of blood sugar reduction, its raw material includes 150 parts of dark green tea, 2 parts of Radix Angelicae Sinensis, Du in parts by weight Secondary 10 parts, 150 parts of honeysuckle, 10 parts of ganoderma lucidum, 120 parts of fructus lycii, 10 parts of Radix Polygalae, 10 parts odd sub-, 40 parts of elscholtiza, 150 parts of chrysanthemum, 80 parts of mulberry leaf, 0.8 part of isomalto-oligosaccharide.
Embodiment 4
A kind of health food with function of blood sugar reduction, its raw material includes 50 parts of dark green tea, 8 parts of Radix Angelicae Sinensis, Du in parts by weight Secondary 40 parts, 50 parts of honeysuckle, 40 parts of ganoderma lucidum, 50 parts of fructus lycii, 15 parts of Radix Polygalae, odd sub- 80 parts, 10 parts of elscholtiza, 50 parts of chrysanthemum, mulberry 10 parts of leaf, 0.2 part of isomalto-oligosaccharide.
Embodiment 5
A kind of health food with function of blood sugar reduction, its raw material includes 120 parts of dark green tea, 3 parts of Radix Angelicae Sinensis, Du in parts by weight Secondary 15 parts, 70 parts of honeysuckle, 15 parts of ganoderma lucidum, 80 parts of fructus lycii, 12 parts of Radix Polygalae, odd sub- 50 parts, 30 parts of elscholtiza, 85 parts of chrysanthemum, mulberry 60 parts of leaf, 0.6 part of isomalto-oligosaccharide.
Embodiment 6
A kind of health food with function of blood sugar reduction is formulated same as Example 1, the preparation method of the health food The following steps are included:
1) ingredient；Required raw material is weighed according to the ratio；
2) after mixing Radix Angelicae Sinensis, Cortex Eucommiae, ganoderma lucidum, Radix Polygalae, odd sub-, elscholtiza, 90% alcohol reflux of 5 times of weight is added to extract 3 Secondary, 0.5 hour every time, filtration, merging filtrate concentrated the filtrate to clear cream (1.30,30 DEG C of relative density), and ethyl alcohol, which is added, to be made Alcohol content obtains solution I up to 75%；
3) after mixing dark green tea, honeysuckle, fructus lycii, chrysanthemum, mulberry leaf, the water of 5 times of weight is added to decoct 3 times, 0.5 is small every time When, collecting decoction, filtration concentrates the filtrate to clear cream (1.30,30 DEG C of relative density), and add ethyl alcohol to make alcohol content up to 75%, Obtain solution II；
4) merge the solution I and solution II, stir evenly, stand, it is (relatively close to be concentrated into clear cream for filtration, filtrate recycling ethanol Degree is 1.30,30 DEG C)；Isomalto-oligosaccharide is added by formula, active mixture is made；100 parts of the active mixture is taken, is added 12.5 parts of maltodextrin, 55.5 parts of microcrystalline cellulose are uniformly mixed, and add ethanol in proper amount solution softwood, and 16 meshes are pelletized, and 60 DEG C It is dry, 12 mesh sieves, that is, granule.
20g/ bags of product specification；It is recommended that eating method and amount: 2 times a day, one bag each time, warm boiled water；Shelf-life 24 months；Storage practice room temperature, ventilation, it is dry at.
Embodiment 7
A kind of health food with function of blood sugar reduction is formulated same as Example 2, the preparation method of the health food The following steps are included:
1) ingredient；Required raw material is weighed according to the ratio；
2) after mixing Radix Angelicae Sinensis, Cortex Eucommiae, ganoderma lucidum, Radix Polygalae, odd sub-, elscholtiza, 50% alcohol reflux of 10 times of weight is added to extract 1 Secondary, 3.0 hours every time, filtration, merging filtrate concentrated the filtrate to clear cream (1.10,30 DEG C of relative density), and ethyl alcohol, which is added, to be made Alcohol content obtains solution I up to 70%；
3) after mixing dark green tea, honeysuckle, fructus lycii, chrysanthemum, mulberry leaf, the water of 15 times of weight is added to decoct 1 time, 2 is small every time When, collecting decoction, filtration concentrates the filtrate to clear cream (1.10,30 DEG C of relative density), and add ethyl alcohol to make alcohol content up to 70%, Obtain solution II；
4) merge the solution I and solution II, stir evenly, stand, it is (relatively close to be concentrated into clear cream for filtration, filtrate recycling ethanol Degree is 1.10,30 DEG C)；Isomalto-oligosaccharide is added by formula, active mixture is made；100 parts of the active mixture is taken, is added 12.5 parts of maltodextrin, 55.5 parts of microcrystalline cellulose are uniformly mixed, and add ethanol in proper amount solution softwood, and 16 meshes are pelletized, and 60 DEG C It is dry, 12 mesh sieves, that is, granule.
20g/ bags of product specification；It is recommended that eating method and amount: 2 times a day, one bag each time, warm boiled water；Shelf-life 24 months；Storage practice room temperature, ventilation, it is dry at.
Embodiment 8
A kind of health food with function of blood sugar reduction is formulated same as Example 3, the preparation method of the health food The following steps are included:
1) ingredient；Required raw material is weighed according to the ratio；
2) will after Radix Angelicae Sinensis, Cortex Eucommiae, ganoderma lucidum, Radix Polygalae, odd sub-, elscholtiza mix, extracted 2 times, the 1st time with 70% alcohol reflux plus Enter 8 times of w ethanols and extract 3h, 6 times of w ethanols of the 2nd addition extract 1h, filtration, and merging filtrate concentrates the filtrate to clear cream (1.10,30 DEG C of relative density), ethyl alcohol, which is added, makes alcohol content up to 70%, obtains solution I；
3) it after mixing dark green tea, honeysuckle, fructus lycii, chrysanthemum, mulberry leaf, adds water to cook 2 times, 10 times of weight of the 1st addition Water decocts 2h, and 8 times of w ethanols are added for the 2nd time and extract 1h, collecting decoction, filtration, and concentrating the filtrate to clear cream, (relative density is 1.10,30 DEG C), add ethyl alcohol to make alcohol content up to 70%, obtains solution II；
4) merge the solution I and solution II, stir evenly, stand, it is (relatively close to be concentrated into clear cream for filtration, filtrate recycling ethanol Degree is 1.10,30 DEG C)；Isomalto-oligosaccharide is added by formula, active mixture is made；100 parts of the active mixture is taken, is added 12.5 parts of maltodextrin, 55.5 parts of microcrystalline cellulose are uniformly mixed, and add ethanol in proper amount solution softwood, and 16 meshes are pelletized, and 60 DEG C It is dry, 12 mesh sieves, that is, granule.
20g/ bags of product specification；It is recommended that eating method and amount: 2 times a day, one bag each time, warm boiled water；Shelf-life 24 months；Storage practice room temperature, ventilation, it is dry at.
Embodiment 9
A kind of health food with function of blood sugar reduction is formulated same as Example 5, the preparation method of the health food The following steps are included:
1) ingredient；Required raw material is weighed according to the ratio；
2) will after Radix Angelicae Sinensis, Cortex Eucommiae, ganoderma lucidum, Radix Polygalae, odd sub-, elscholtiza mix, extracted 2 times, the 1st time with 75% alcohol reflux plus Enter 8 times of w ethanols and extract 3h, 6 times of w ethanols of the 2nd addition extract 1h, filtration, and merging filtrate concentrates the filtrate to clear cream (1.30,30 DEG C of relative density), ethyl alcohol, which is added, makes alcohol content up to 75%, obtains solution I；
3) it after mixing dark green tea, honeysuckle, fructus lycii, chrysanthemum, mulberry leaf, adds water to cook 2 times, 10 times of weight of the 1st addition Water decocts 2h, and 8 times of w ethanols are added for the 2nd time and extract 1h, collecting decoction, filtration, and concentrating the filtrate to clear cream, (relative density is 1.30,30 DEG C), add ethyl alcohol to make alcohol content up to 75%, obtains solution II；
4) merge the solution I and solution II, stir evenly, stand, it is (relatively close to be concentrated into clear cream for filtration, filtrate recycling ethanol Degree is 1.30,30 DEG C)；Isomalto-oligosaccharide is added by formula, active mixture is made；100 parts of the active mixture is taken, is added 12.5 parts of maltodextrin, 55.5 parts of microcrystalline cellulose are uniformly mixed, and add ethanol in proper amount solution softwood, and 16 meshes are pelletized, and 60 DEG C It is dry, 12 mesh sieves, that is, granule.
20g/ bags of product specification；It is recommended that eating method and amount: 2 times a day, one bag each time, warm boiled water；Shelf-life 24 months；Storage practice room temperature, ventilation, it is dry at.
Embodiment 10
A kind of health food with function of blood sugar reduction is formulated same as Example 4, the preparation method of the health food With embodiment 9.
20g/ bags of product specification；It is recommended that eating method and amount: 2 times a day, one bag each time, warm boiled water；Shelf-life 24 months；Storage practice room temperature, ventilation, it is dry at.
Embodiment 11
A kind of health food with function of blood sugar reduction, formula is same as Example 1, for manufactured bag according to a conventional method Fill medicinal tea.
Embodiment 12
A kind of health food with function of blood sugar reduction, formula is same as Example 2, for manufactured glue according to a conventional method Wafer.
Embodiment 13
A kind of health food with function of blood sugar reduction, formula is same as Example 3, and preparation method includes first by real Obtained active mixture is made in the method for applying example 8；Tablet is made in conventional method again.
Embodiment 14
A kind of health food with function of blood sugar reduction, formula is same as Example 4, and preparation method includes first by real Obtained active mixture is made in the method for applying example 9；Capsule is made in conventional method again.
Embodiment 15
A kind of health food with function of blood sugar reduction, formula is same as Example 5, and preparation method includes first by real Obtained active mixture is made in the method for applying example 8；Tablet is made in conventional method again.
Comparative example
A kind of dark green tea granule, active constituent are only dark green tea；Preparation method is same as Example 9, and (but raw material does not wrap Include the Chinese medicine and isomalto-oligosaccharide except dark green tea).
The experiment of experimental example function of blood sugar reduction
1, test crowd: 100 adult type II diabetes people of selection, the age 18-65 years old, men and women was fifty-fifty.Subject is included in Standard is to select the age 18-65 years old, and stable disease after diet control or oral hypoglycemic agents treatment does not need replacement types of drugs And dosage, only take the adult type II diabetes people of maintenance dose, fasting blood-glucose >=7.8mmol/L or 2h-plasma glucose >= 11.1mmol/L。
2, experimental design and grouping: by subject's blood glucose level, gender, age, the course of disease, medication, type is balanced is randomly divided into Experimental group and control group, every group of 50 people.
3, test method: experimental group takes sample prepared by the embodiment of the present invention 9 daily, and dosage is 2 times a day every time 1 Bag (20g/ bags), boiled water is drunk after brewing.Control group takes the dark green tea granule of comparative example preparation, control group taking dose and side Method is identical as experimental group.Test period 30 days.Gender, age, different labor intensity, ideal body are pressed to each subject before test Weight provides corresponding diet referring to original living habit, and each group adheres to diet control, former medicament categories and dosage during test It is constant.
4, functional observation: clinical symptoms during observation subject's test, and measure fasting blood-glucose, postprandial blood sugar and glucose in urine.
5, test result
5.1 clinicing symptom observation
1 clinical symptoms of table integral statistics (x ± s)
Group Number of cases Before test-meal After test-meal
Control group 50 5.59±3.27 5.47±3.12
Experimental group 50 5.73±3.41 3.65±2.61*#
Note: * P < 0.05 compared with experimental group；# P < 0.05 compared with the control group.
2 clinical symptoms of table improve situation
By table 1,2 as it can be seen that experimental group clinical symptoms have clear improvement, compared with the control group, significant difference (P < 0.05).
5.2 fasting blood-glucose
Fasting blood-glucose variation (unit: mmol/L, x ± s) before and after 3 test-meal of table
Group number of cases (n) Before test-meal After test-meal Blood glucose fall Decline percentage %
Control group 50 9.10±2.00 9.06±2.03 0.03±0.22 0.44
Experimental group 50 9.13±2.11 7.97±2.02*# 1.15±0.51*# 12.71
Note: * P < 0.05 compared with experimental group；# P < 0.05 compared with the control group.
5.3 postprandial blood sugar
Postprandial blood sugar variation (unit: mmol/L, x ± s) before and after 4 test-meal of table
Group number of cases (n) Before test-meal After test-meal Blood glucose fall Decline percentage %
Control group 50 12.20±2.11 12.15±2.05 0.05±0.25 0.41
Experimental group 50 12.23±2.21 11.09±2.24*# 1.13±0.62*# 9.32
Note: * P < 0.05 compared with experimental group；# P < 0.05 compared with the control group
6, conclusion
Experimental group takes 9 sample of the embodiment of the present invention and the main clinic symptoms of hyperglycemia is significantly improved； Experimental group fasting blood-glucose, postprandial blood sugar and glucose in urine, itself compare before and after test-meal and experimental group compared with the control group, difference has aobvious Work property (P < 0.05).Test result shows that product of the present invention has hypoglycemic health-care effect.
The dosage form that granule is taken in this experimental example keeps drug administration simple and easy, effectively raises the absorption of drug And utilize, in addition, what the present invention took is pure natural medical, any toxic additive and addictive drug are not added, it will not Appetite-suppressing not will lead to diarrhea, have no toxic side effect, not habituation.It also found when experiment, the weight of most of experimental group subject Mitigated, and blood lipid, blood pressure have different degrees of reduction, digestion has improvement, and mental attitude significantly improves, and prompts the present invention also With health-care effects such as reducing blood lipid, blood pressure lowering and weight-reducing.
Although above the present invention is described in detail with a general description of the specific embodiments, On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause This, these modifications or improvements, fall within the scope of the claimed invention without departing from theon the basis of the spirit of the present invention.

Claims (9)

1. a kind of health food with function of blood sugar reduction, which is characterized in that in parts by weight, be prepared from the following raw materials: dark green tea 10-200 parts, 1-10 parts of Radix Angelicae Sinensis, 5-50 parts of Cortex Eucommiae, 10-200 parts of honeysuckle, 5-50 parts of ganoderma lucidum, 10-150 parts of fructus lycii, Radix Polygalae 5-20 parts, odd 5-100 parts of Asia, 5-50 parts of elscholtiza, 10-200 parts of chrysanthemum, 5-100 parts of mulberry leaf, 0.1-1 parts of isomalto-oligosaccharide；
The preparation method of the health food the following steps are included:
1) ingredient；
2) after mixing Radix Angelicae Sinensis, Cortex Eucommiae, ganoderma lucidum, Radix Polygalae, odd sub-, elscholtiza, the 50%-90% alcohol reflux of 5-10 times of weight is added to mention It takes 1-3 times, 0.5-3.0 hours each, filtration, merging filtrate concentrates the filtrate to clear cream, and ethyl alcohol, which is added, reaches alcohol content 70%-75% obtains solution I；
3) after mixing dark green tea, honeysuckle, fructus lycii, chrysanthemum, mulberry leaf, the water of 5-15 times of weight is added to decoct 1-3 times, each 0.5- 2 hours, collecting decoction, filtration concentrated the filtrate to clear cream, adds ethyl alcohol to make alcohol content up to 70%-75%, obtains solution II；
4) merge the solution I and solution II, stir evenly, stand, filtration, filtrate recycling ethanol is concentrated into clear cream；It is added by formula Suitable dosage form is made in isomalto-oligosaccharide and appropriate amount of auxiliary materials.
2. health food according to claim 1, which is characterized in that the preparation method of the health food, including it is following Step:
1) ingredient；
2) it after mixing Radix Angelicae Sinensis, Cortex Eucommiae, ganoderma lucidum, Radix Polygalae, odd sub-, elscholtiza, is extracted 2 times, the 1st time with 70%-75% alcohol reflux 8 times of w ethanols are added and extract 3h, 6 times of w ethanols of the 2nd addition extract 1h, filtration, and merging filtrate concentrates the filtrate to clear Cream, ethyl alcohol, which is added, makes alcohol content up to 70%-75%, obtains solution I；
3) it after mixing dark green tea, honeysuckle, fructus lycii, chrysanthemum, mulberry leaf, adds water to cook 2 times, 10 times of weight decoctings of the 1st addition 2h is boiled, 8 times of w ethanols of the 2nd addition extract 1h, collecting decoction, and filtration concentrates the filtrate to clear cream, ethyl alcohol is added to make alcohol content Up to 70%-75%, solution II is obtained；
4) merge the solution I and solution II, stir evenly, stand, filtration, filtrate recycling ethanol is concentrated into clear cream；It is added by formula Suitable dosage form is made in isomalto-oligosaccharide and appropriate amount of auxiliary materials.
3. health food according to claim 1 or 2, which is characterized in that in parts by weight, be prepared from the following raw materials: black It is 50-150 parts of tea, 2-8 parts of Radix Angelicae Sinensis, 10-40 parts of Cortex Eucommiae, 50-150 parts of honeysuckle, 10-40 parts of ganoderma lucidum, 50-120 parts of fructus lycii, remote 10-15 parts of will, odd 10-80 parts of Asia, 10-40 parts of elscholtiza, 50-150 parts of chrysanthemum, 10-80 parts of mulberry leaf, isomalto-oligosaccharide 0.2- 0.8 part.
4. health food according to claim 1 or 2, which is characterized in that in parts by weight, be prepared from the following raw materials: black 120 parts of tea, 3 parts of Radix Angelicae Sinensis, 15 parts of Cortex Eucommiae, 70 parts of honeysuckle, 15 parts of ganoderma lucidum, 80 parts of fructus lycii, 12 parts of Radix Polygalae, odd 50 parts sub-, perfume 30 parts of Ru, 85 parts of chrysanthemum, 60 parts of mulberry leaf, 0.6 part of isomalto-oligosaccharide.
5. health food according to claim 4, which is characterized in that the preparation method of the health food includes following step It is rapid:
1) ingredient；Required raw material is weighed according to the ratio；
2) it after mixing Radix Angelicae Sinensis, Cortex Eucommiae, ganoderma lucidum, Radix Polygalae, odd sub-, elscholtiza, is extracted 2 times with 75% alcohol reflux, the 1st addition 8 Times w ethanol extracts 3h, 6 times of w ethanols is added and extract 1h, filtration, merging filtrate, when concentrating the filtrate to 30 DEG C for the 2nd time The clear cream that relative density is 1.30, ethyl alcohol, which is added, makes alcohol content up to 75%, obtains solution I；
3) it after mixing dark green tea, honeysuckle, fructus lycii, chrysanthemum, mulberry leaf, adds water to cook 2 times, 10 times of weight decoctings of the 1st addition 2h is boiled, 8 times of w ethanols of the 2nd addition extract 1h, and collecting decoction, filtration, relative density is when concentrating the filtrate to 30 DEG C 1.30 clear cream adds ethyl alcohol to make alcohol content up to 75%, obtains solution II；
4) merge the solution I and solution II, stir evenly, stand, filtration, filtrate recycling ethanol, relative density when being concentrated into 30 DEG C For 1.30 clear cream；Isomalto-oligosaccharide is added by formula, active mixture is made；100 parts of the active mixture is taken, wheat is added 12.5 parts of bud dextrin, 55.5 parts of microcrystalline cellulose are uniformly mixed, and add ethanol in proper amount solution softwood, the granulation of 16 meshes, 60 DEG C dry Dry, granule is made in 12 mesh sieves.
6. health food according to claim 1-4, which is characterized in that the auxiliary material further includes pharmaceutically or eating Acceptable carrier on product or on health food.
7. health food according to claim 1-4, which is characterized in that the health food is formed into oral system Agent；The oral preparation are as follows: capsule, granule, tablet or packed medicinal tea.
8. health food according to claim 1-4, which is characterized in that the health food is pulvis.
9. health food according to claim 1-4, which is characterized in that the health food is granule, institute Stating auxiliary material is microcrystalline cellulose and magnesium stearate.
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CN106172965A (en) * 2016-06-30 2016-12-07 安化盈泰丰农业发展有限公司 A kind of novel ANHUA HEI CHA of natural environmental-protective U.S. face and preparation method thereof
CN106418529A (en) * 2016-08-02 2017-02-22 马佳 Preparation method of chrysanthemum oral liquid capable of improving immunity and oral liquid thereof
CN108260682A (en) * 2018-01-16 2018-07-10 刘畅 A kind of hypoglycemic, reducing blood lipid and the health protection tea of blood pressure lowering
JP2019022520A (en) * 2018-10-19 2019-02-14 株式会社東洋新薬 Composition

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1915050A (en) * 2006-08-31 2007-02-21 王学清 Ganoderma lucidum tea and fabricating technique
CN101401601A (en) * 2006-10-18 2009-04-08 吴建生 Five-leaf tea for reducing blood pressure, blood fat and blood sugar
CN102919836A (en) * 2012-11-09 2013-02-13 刘东元 Health-care product capable of reducing blood glucose, releasing pressure, reducing lipid, relaxing bowel, beautifying, losing weight and resisting fatigue and production process thereof
CN103705578A (en) * 2013-12-18 2014-04-09 广西中医药大学 Traditional Chinese medicine preparation with functions of reducing blood fat and inhibiting blood glucose increase and preparation method thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002370994A (en) * 2001-06-08 2002-12-24 Kirin Brewery Co Ltd Blood sugar value elevation-inhibiting substance and functional beverage or food containing the same
CN1274242C (en) * 2004-08-12 2006-09-13 陈希萍 Method for preparing probiotics product based on human somatology
CN1305405C (en) * 2004-12-09 2007-03-21 桂林莱茵生物制品有限公司 Health food with subsidiary function of lowering blood sugar and lowering blood fat and its production process
CN1660387A (en) * 2004-12-29 2005-08-31 韦平生 Health care preparation for regulating functional balance of organs of bowels in human body and preparing method
CN101233912A (en) * 2007-10-24 2008-08-06 杨啸 Health care functional common salt
CN103141606A (en) * 2013-03-12 2013-06-12 胡孔佑 Instant dark green tea for nourishing blood and tonifying qi and preparation method thereof
CN103315090B (en) * 2013-07-11 2014-06-11 山东华夏茶联茶业有限公司 Preparation method of dark tea

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1915050A (en) * 2006-08-31 2007-02-21 王学清 Ganoderma lucidum tea and fabricating technique
CN101401601A (en) * 2006-10-18 2009-04-08 吴建生 Five-leaf tea for reducing blood pressure, blood fat and blood sugar
CN102919836A (en) * 2012-11-09 2013-02-13 刘东元 Health-care product capable of reducing blood glucose, releasing pressure, reducing lipid, relaxing bowel, beautifying, losing weight and resisting fatigue and production process thereof
CN103705578A (en) * 2013-12-18 2014-04-09 广西中医药大学 Traditional Chinese medicine preparation with functions of reducing blood fat and inhibiting blood glucose increase and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
奇亚籽急性毒性及遗传毒性研究;李淑琴；等;《癌变.畸变.突变》;20131231;第25卷(第6期);470-473 *
异麦芽低聚糖的生产及生理功能;耿予欢；等;《食品工业》;19971231(第3期);3-4 *
黑茶加工工艺与保健功能研究;何煜波；等;《安徽农业科学》;20121231;第40卷(第27期);13595——13597、13600 *

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