CN105770773A - Traditional Chinese medicinal preparation for treating adult mild brain disturbance and preparation method of traditional Chinese medicinal preparation - Google Patents

Traditional Chinese medicinal preparation for treating adult mild brain disturbance and preparation method of traditional Chinese medicinal preparation Download PDF

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CN105770773A
CN105770773A CN201610309015.5A CN201610309015A CN105770773A CN 105770773 A CN105770773 A CN 105770773A CN 201610309015 A CN201610309015 A CN 201610309015A CN 105770773 A CN105770773 A CN 105770773A
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radix
rhizoma
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徐芳
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Abstract

The invention discloses a traditional Chinese medicinal preparation for treating adult mild brain disturbance. The traditional Chinese medicinal preparation is prepared from Chinese trumpetcreeper flower, rhizoma typhonii, radix ophiopogonis, rhizoma acori graminei, radix achyranthis bidentatae, fructus ligustri lucidi, earthworm, fructus viticis, radix salviae miltiorrhizae, herba schizonepetae, concha margaritifera usta, periostracum cicadae, herba dendrobii, fried bombyx batryticatus, radix paeoniae alba, Bupleurum chinense DC semen platycladi, semen ziziphi spinosae, crude dragon bone, raw oyster shell, rhizoma gastrodiae, radix glehniae, radix curcumae and carapax et plastrum testudinis according to a certain weight proportion. The traditional Chinese medicinal preparation has the efficacy of inducing resuscitation and eliminating phlegm, clearing brain and eyes, eliminating phlegm and arresting convulsion, and tranquilizing by nourishing the heart, and has remarkable treatment effects.

Description

A kind of Chinese medicine preparation treating adult mild brain disturbance and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation treating adult mild brain disturbance, the preparation method that the invention still further relates to this Chinese medicine preparation.
Background technology
People generally think, hyperkinetic syndrome is the disease of child, and can spontaneous recovery with advancing age, this disease will not be there is in adult.But follow-up observation according to a lot of scholars and perspective study, it has been found that hyperkinetic syndrome is not the disease that child is proprietary.Treating not in time if child has suffered from hyperkinetic syndrome, can continue until the between twenty and fifty stage, only Symptoms is different, we term it " minimum brain dysfunction of growing up (is called for short AMBD) ", i.e. adult mild brain disturbance.Adult mild brain disturbance's clinical manifestation many with irritable, easily fly into a rage, anxiety, depression etc. are for feature.It is, in general, that with age, the hyperkinetic syndrome shape of infant can go down, but still have unpeace, irritability, impulsion, easily divert one's attention, attention is difficult to concentrate, school achievement is poor, sense of personal worth is low, depressed, easily lose heart etc..There are about the infant of 1/4th and antisocial behavior can occur, as bellicose, steal, destroy, set on fire, do violence and hurt sb.'s feelings.It is believed that, after this kind of infant is grown up, insane chance relatively population wants many.Also have quite a few child, after growing up, environment maladjustment can occur.
Adult mild brain disturbance the cause of disease mainly have following some: 1, slight brain tissue damage: viral infection during such as gestation, take medicine, asphyxia of newborn, maternal infuries, cerebral anoxia caused by many reasons, brain injury etc..2, inherited genetic factors.3, in brain, neurotransmitter metabolism is abnormal, and dopamine, 5-hydroxy tryptamine, acetylcholine lack.4, vitamin deficiency, food anaphylaxis, metabolism obstacles of blood glucose.5, psychological factor: relevant with bad domestic environment and educational method, such as kinsfolk's strained relations, lacks tender feeling, or child is too overcritical, spoil roughly or excessively, docile, or be subject to corporal punishment or discrimination etc. improperly in school.6 and the shortage or poisoning relevant of trace element, such as iron deficiency, zinc, magnesium and manganese, and lead poisoning is all relevant with hyperkinetic syndrome morbidity.Wherein inherited genetic factors is one of adult mild brain disturbance's Etiological: have scholar that childhood hyperkinetic syndrome has carried out family line investigation, twins study, adopted son's research etc., think that this disease is relevant with inherited genetic factors, and point out, inherited genetic factors plays in hyperkinetic syndrome is fallen ill than environmental factors and more importantly acts on.
The method of current western medical treatment primary disease is a lot, but great majority can only achieve recent clinical effectiveness, and long-term effect is not good, and can not only recur, and long-term taking Western medicine, the hepatic and renal function of patient is all caused irreversible damage, there is toxic and side effects in various degree.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation treating adult mild brain disturbance, this Chinese medicine preparation has determined curative effect for adult mild brain disturbance, cheap, safe ready, the little feature of side effect.
Inventor is in clinical treatment for many years is put into practice, law of development according to this disease, and the combination principle of Chinese medicine, and by substantial amounts of clinical verification, Exploration and conclusion goes out the new formula of a kind of Chinese medicine preparation treating adult mild brain disturbance repeatedly, the present invention selects Flos Campsis, Rhizoma Typhonii, Radix Ophiopogonis, Rhizoma Acori Graminei, Radix Achyranthis Bidentatae, Fructus Ligustri Lucidi, Pheretima, Fructus Viticis, Radix Salviae Miltiorrhizae, Herba Schizonepetae, Concha Margaritifera, Periostracum Cicadae, Herba Dendrobii, Bombyx Batryticatus (parched), the Radix Paeoniae Alba, Radix Bupleuri, Semen Platycladi, Semen Ziziphi Spinosae, Os Draconis, Concha Ostreae, Rhizoma Gastrodiae, Radix Glehniae, Radix Curcumae, Carapax et Plastrum Testudinis is combined, make generation synergism between each medicine, there is eliminating phlegm of having one's ideas straightened out, the cleaning head, eliminate the phlegm arresting convulsion, effect of tranquilizing by nourishing the heart, it is thus possible to effective adult mild brain disturbance.
The effect of Chinese medicine of the present invention:
Wherein:
Flos Campsis: reach the clouds Campsisgrandiflora (Thunb.) K.Schum. for bavin Wei section plant or reach the clouds the dried floral of Campsisradicans (L.) Seem. and root in America.Nature and flavor: flower: sweet, sour, cold.Root: bitter is cool.Flower: return liver, pericardium channel.Effect: flower: removing heat from blood, blood stasis dispelling, dispels the wind.For menoxenia, amenorrhea abdominal mass, puerperal swelling of the breast, rubella is rubescent, skin pruritus, acne.Root: promoting blood circulation to remove blood stasis, removing toxic substances and promoting subsidence of swelling.
Rhizoma Typhonii: for the dry tuber of aroid Herba Typhonii gigantei TyphoniumgiganteumEngl..Nature and flavor: pungent, warm, poisonous.Return stomach, Liver Channel.Effect: dispel the wind expectorant, and arresting convulsion is jerked, detoxicating and resolving stagnation of pathogens pain relieving.Stopping up for middle wind-phlegm, facial hemiparalysis, language is puckery stuttering, and syncope due to accumulation of phlegm is had a headache, migraine and general headache, sore throat pharyngalgia, tetanus；External treatment scrofula sucutaneous nodule, venom, tetanus, carbuncle.
Radix Ophiopogonis: for the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf) Ophiopogonjaponicus (Thunb.) Ker-Gawl..Nature and flavor: hardship sweet, micro-, be slightly cold.GUIXIN, lung, stomach warp.Effect: reinforcing stomach reg fluid, nourishing lung-YIN, clear away heart-fire relieving restlessness.Radix Ophiopogonis can clear away heart-fire in yin nourishing, and relieving restlessness is calmed the nerves.The heart-nutriment, fever aggravated at night is entered with controlling warm febrile disease.
Rhizoma Acori Graminei: for the dry rhizome of acorus gramineus araceae plant AcorustatarinowiiSchott.Nature and flavor: pungent, bitter, temperature.GUIXIN, stomach warp.Effect: removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Rhizoma Acori Graminei has anticonvulsant action, and the volatile oil of Rhizoma Acori Graminei has sedation of calming the nerves, the secretion of Rhizoma Acori Graminei decoct energy for oral administration facilitating digestion liquid." herbal classic ": " main anemofrigid-damp arthralgia, cough with dyspnea, happy hole, tonifying five ZANG-organs, logical nine orifices, bright knowledge, go out speech." " Chongqing hall random notes ": Rhizoma Acori Graminei, comfortable gas, the smooth mind, happy mood, benefit will, panacea is also.Removing summer-heat medicinal it, rely and eliminate the phlegm dirty turbid and defend city wall, nourish medicinal it, so as to declaring the knot of thought and being proficient in the law of natural movement.
Radix Achyranthis Bidentatae: for the root of Amaranthus mangostanus L. section herbaceos perennial Radix Achyranthis Bidentatae or RADIX CYATHULAE.Nature and flavor: bitter, sour, flat.Return liver, kidney channel.Effect: eliminating blood stasis and inducing menstruation, conducting blood to flow downwards, invigorating the liver and kidney, bone and muscle strengthening.
Fructus Ligustri Lucidi: for the dry mature fruit of Oleaceae plants Fructus Ligustri Lucidi LigustrumlucidumAit..Nature and flavor: bitter, sweet, flat, nontoxic.Return liver, kidney, lung meridian.Effect: invigorating the liver and kidney, strong waist knee joint.Cure mainly: yin asthenia generating intrinsic heat, dizzy, order flower, tinnitus, soreness of the waist and knees, early whitening of beard and hair.Modern pharmacology is studied: Fructus Ligustri Lucidi can enhancing non-specific immunity function, abnormal immunologic function is had dual regulation；Leukopenia caused by chemotherapy and radiation there is rising effect；The serum cholesterol of laboratory animal can be reduced, have prevention and abatement atheromatous plaque and alleviate the effect of plaque thickness, coronary atherosclerosis number can be reduced and alleviate its degree of congestion；Can substantially reduce mda content in Mus brain at advanced age, liver, improve superoxide dismutase (SOD) activity, have certain defying age using value；There are heart tonifying, diuresis, blood sugar lowering and hepatoprotective effect.
Pheretima: for the dry body of Ju Yin section animal Pheretima aspergillum Pheretimaaspergillum (E.Perrier), popular Pheretimatschiliensis PheretimavulgarisChen, power simulation Pheretimaguillelmi (Michaelsen) or the blind Pheretimatschiliensis PheretimapectiniferaMichaelsen of comb.Nature and flavor: salty, cold.Return liver, spleen, bladder warp.Effect: heat clearing away is calmed the frightened, dredge the meridian passage, clearing heat and relieving dyspnea, relieving stranguria by diuresis.This product is cold in nature, can endogenous wind stopping relieving convulsion, be good at again heat clearing away arresting convulsion, thus be applicable to unconsciousness and delirium caused by extreme heat causing wind syndrome, spasm is twitched and infantile convulsion, or epilepsy, the disease such as demented.
Fructus Viticis: for the dry mature fruit of Verbenaceae Vitex rotundifolia VitextrifoliaL.var.simplicifoliaCham. or wild pepper VitextrifoliaL..Nature and flavor: pungent, bitter, are slightly cold.Return bladder, liver, stomach warp.Effect: dispelling wind and heat pathogens, the clear profit head.Have a headache for anemopyretic cold, gingivitis, the many tear of conjunctival congestion, poor vision, have a dizzy spell." book on Chinese herbal medicine converges and says ": Fructus Viticis, the medicine of all wind diseases of main head is also.The main tonneau nine orifices of front Gu, profit of living joint, improving eyesight heavily fortified point tooth, the heresy of removing cold and wind wind heat.Its pungent temperature gently dissipates, floating and up, therefore the main all cards of head wind syndrome caused by deficiency.Push away its logical nine orifices, profit joint, therefore control arthralgia chiefly caused by damp pathogen contracture later age, colic of cold type beriberi, enter during soup dissipates, repeatly with proving effective, be not limited to again head top also.
Radix Salviae Miltiorrhizae: for the dry root and rhizome of dicotyledon Labiatae Labiatae salvia Radix Salviae Miltiorrhizae Salvia/miltiorrhizaBge.Nature and flavor: bitter, are slightly cold.Gui Jing: enter the heart, Liver Channel.Effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, clear away heart-fire relieving restlessness, nourishing blood to tranquillize the mind.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen lumps." Japan hanako materia medica ": sedate of reposing, tonneau GUAN-pulse.Controlling cold and hot labor, arthralgia, extremity are unsuccessful；Evacuation of pus pain relieving, granulation promoting is put on flesh；Broken stagnated blood, mends new hemopoietic；Peaceful tire, fall stillborn fetus；Under hemostasis metrorrhagia and leukorrhagia, adjusting married woman's passages through which vital energy circulates irregular, blood evil thought is tired of；Malignant boil scabies, wart is gone to live in the household of one's in-laws on getting married toxic swelling, erysipelas；Headache, acute conjunctivitis, heat temperature is mad vexed.Modern medicine, it is demonstrated experimentally that Radix Salviae Miltiorrhizae also has anti-platelet aggregation, reduces blood viscosity and regulate the function of inside and outside blood coagulation system, is a kind of safety natural Chinese medicine for the treatment of again thrombus disease reliably.
Herba Schizonepetae: for the dry aerial parts of labiate Herba Schizonepetae SchizonepetatenuifoliaBriq..Nature and flavor: pungent, bitter, micro-wet.Return lung, Liver Channel.Effect: dispel the wind；Induce sweat；Rash；Hemostasis.Main cold, fever；Headache；Eye itching；Cough；Laryngopharynx swelling and pain；Measles；Carbuncle；Skin ulcer scabies；Epistaxis；Spit blood；Have blood in stool；Metrorrhagia；Puerperal blood faints.This product Chhnang dissipates thoroughly, can dispelling wind for relieving itching, a surname dissipates measles toxin, can be used for measles without adequate eruption, rubella pruritus, additionally Herba Schizonepetae can be additionally used in skin infection from the beginning of, relatively wind heat this, compatibility Flos Lonicerae etc., Herba Schizonepetae and Radix Saposhnikoviae mutual reinforcement between are use, strengthen expelling pathogenic wind from the body surface effect.
Concha Margaritifera: for the shell of Unionidae animal hydriopsis cumingii Hyriopsiscumingii (Lea), cristaria plicata Cristariaplicata (Leach) or Pteriidae animal Pteria martensii Dunker Pteriamartensii (Dunker).Nature and flavor: salty, cold.Return liver, heart channel.Effect: suppressing the hyperactive liver and subsiding YANG, improving eyesight of calming the frightened.For dizziness of having a headache, irritated insomnia, liver-heat conjunctival congestion, deficiency of the liver blurred vision." Chinese medicine voluminous dictionary ": liver nourishing is cloudy, clearing away liver-fire.Controlling demented infantile convulsion, dizziness, tinnitus, heart beating, pleuroperitoneum is swollen, women's heat in blood, metrorrhagia, and frightened the jerking of children's sends out convulsion.
Periostracum Cicadae: for cicada Cryptotympana atrata Fabr. CryptotympanapustulataFabricius larva sprout wings time exuviae shell.Nature and flavor: sweet, cold.Return lung, Liver Channel.Effect: dispelling wind and heat pathogens, rash are antipruritic, improving acuity of vision and removing nebula, endogenous wind stopping relieving convulsion.This product a surname dissipates and thoroughly sends out, and wind-dispelling heat-dissipating, antipruritic can be used for of rash treats measles, eczema etc..For diseases such as tetanus, infantile convulsion, night cry.Periostracum Cicadae can be dispelled exogenous wind, can cease endogenous wind and spasmolytic of calming the frightened again, tetanus is occurred tic of the limbs, can join that Scorpio is equivalent to be used；Infantile convulsion, the nocturnal fretfulness in infants are occurred that infantile convulsion is uneasy, the equivalent use of Ramulus Uncariae Cum Uncis can be joined.
Herba Dendrobii: for the fresh or dry stem of orchid dendrobium loddigesii Rolfe DendrobiumloddigesiiRolfe., Herba Dendrobii oculati DendrobiumfimbriatumHook.var.oculatumHook., HERBA DENDROBII DendrobiumchrysanthumWall., Herba Dendrobii DendrobiumcandidumWall.exLindl. or Dendrobium nobile DendrobiumnobileLindl..Nature and flavor: be slightly cold；Sweet.Return stomach, kidney channel.Function: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Losing for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision." explaining abstruseness of the canon of materia medica ": Herba Dendrobii, Gan Keyue spleen, salty energy kidney tonifying, therefore many merits are dirty in water and soil two.But gas width delays, without the merit that victory is played, ancients are with this generation tea, on very clear diaphragm.
Bombyx Batryticatus (parched): infect (or artificial vaccination) muscardine Beauveriabassiana (Bals.) Vuillant and lethal larva dry body for the larva in Bombycidae insecticide silkworm BombyxmoriLinnaeus.4～5 ages.Bombyx Batryticatus (parched), for taking clean Bombyx Batryticatus, is fried to surface yellow according to parched with bran method (annex IID).Nature and flavor: salty, pungent are flat.Return liver, lung, stomach warp.Effect: expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Cure mainly: apoplectic aphasia, middle tuyere nose eye are oblique.Bombyx Batryticatus treatment infantile convulsion is twitched.Bombyx Batryticatus is salty pungent flat, enters liver, lung two warp, can endogenous wind stopping relieving convulsion, arresting convulsion of reducing phlegm again, therefore it is particularly suitable that infantile convulsion, epilepsy are held under the arm the hot person of expectorant.
The Radix Paeoniae Alba: for the dry root of dicotyledon ranunculaceae plant Radix Paeoniae PaeonialactifloraPall..Nature and flavor: cool, picric acid, it is slightly cold.Effect: easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving, yin fluid astringing receives antiperspirant.Research shows: the paeoniflorin contained in the Radix Paeoniae Alba has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves myocardial nutritional flow, expansion blood vessel, antagonism acute myocardial ischemia, suppress the effect of platelet aggregation, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc..This product energy nourishing the liver blood, hold back liver-yin, subduing the hyperfunction of the liver sun, dispersing liver-energy, can delay again that contraction is anxious, relieve the pain pain, for treating the good medicine of the various pain of Liver Channel." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " purgation of spleen excess heat, only abdomen pain, sealing rushes down, and receives adverse flow of liver-QI pain, takes good care of conscience spleen channel blood, relax through sending down the abnormal ascending QI, only irritability pain." " herbal classic " Radix Paeoniae, though do not distinguish red in vain, the two is respectively main to some extent.So seeking and unravel silk it and cure mainly all diseases, one is that replenishing blood and nourishing liver spleen is Kidney-Yin, and receives and take the photograph the at random of temper, irritability throw off restraint horizontal stroke, the then Radix Paeoniae Alba.
Radix Bupleuri: for root or the herb of Umbelliferae herbaceos perennial Radix Bupleuri BupleurumchinenseDC. (Radix Bupleuri) or Radix Bupeuri Scorzonerfolii. BupleurumscorzonerifoliumWilld. (Radix Bupleuri Scorzonerifolii).Nature and flavor: bitter, pungent, be slightly cold.Return liver, gallbladder meridian.Effect: reducing fever by reconciliation, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang.Modern pharmacological research proves: " medicineization justice ": Radix Bupleuri, and property is gently clear, and main liter dissipates, mildly bitter flavor, main soothing the liver." book on Chinese herbal medicine is through solving ": Radix Bupleuri, stagnation of QI person in its main trusted subordinate's the intestines and stomach, trusted subordinate's the intestines and stomach, five hide six mansions also, and Zang Fu is totally ten two warp, gallbladder is all depended in all 11 Tibetan, and Radix Bupleuri is gently clear, rises and reaches courage, and courage bar reaches, then 11 hide from Xuanhua, therefore in trusted subordinate's the intestines and stomach, all have stagnation of QI, all can dissipate also.Its main diet accumulator, lid diet enters stomach, the spleen transporting essential substances to the liver, the evacuation of liver, and also, Radix Bupleuri liter reaches courage to the master borrowing again few sun gallbladder to be hair growth promoting, then liver can dissipate essence, and diet gathers from lower.Shaoyang channel row half exterior and half interior, few sun, by heresy, evil is also then trembled with fear in the moon, evil and in Yang Zere, Radix Bupleuri treating SHAO YANG disease by mediation, therefore the pathogen of main cold and heat is also.Radix Bupleuri has the effect of good dispersing the stagnated live-QI to relieve the stagnation of QI, for treating the key medicine of irritability stasis.
Semen Platycladi: for the dry mature kernal of Cupressaceae plant Cacumen Platycladi Platycladusorientalis (L.) Franco.Nature and flavor: sweet are flat.GUIXIN, kidney, large intestine channel.Effect: tranquilizing by nourishing the heart, hidroschesis, intestine moistening.Have a sleepless night for fidgets due to deficiency, severe palpitation, night sweat due to yin deficiency, dryness of the intestine constipation." medicineization justice ": Semen Platycladi, the saturating heart of fragrance, body profit grows blood.Same Poria cum Radix Pini, Semen Ziziphi Spinosae, the Radix Rehmanniae, Radix Ophiopogonis, for product clear in turbid, curing mainly mind void timid, palpitation with a distress feeling of palpitating with fear, color is wan and sallow, skin pruritus due to dryness, and the merit of the blood that all nourishes heart is also.Take again abnormal smells from the patient all dense, in turbid, return kidney, same to Radix Rehmanniae Preparata, Carapax et Plastrum Testudinis, Fructus Lycii, Radix Achyranthis Bidentatae, for packing bone marrow, cure mainly damage of kidney-YIN, back weight pain, foot knee joint is weak, and night sweat due to yin deficiency, the power that all nourishing kidney is dry is also.Sweet in the mouth also can delay liver, and the deficiency of tonifying liver gallbladder is extremely reliable, but the flat power of property is delayed, should be multiplex be wonderful.
Semen Ziziphi Spinosae: for the dry mature seed of Rhamnaceae plant Ziziphi Spinosae ZiziphusjujubaMill.var.spinosa (Bunge) HuexH.F.Chou.Nature and flavor: flat are sweet, sour.GUIXIN, spleen, liver, gallbladder meridian.
Effect: nourishing the liver, mind calming, calm the nerves, arresting sweating." Bencao Jingshu ": Semen Ziziphi Spinosae, real acid is flat, and core is then held concurrently sweet.Special tonifying liver gallbladder, is also amusing again.Ripe then fragrance, fragrance enters spleen, therefore can return spleen.Courage can be mended, therefore can temperature gallbladder.The gas phase of mothers and sons lead to, therefore also main fidgets due to deficiency, vexatious insomnia.Its main trusted subordinate's cold and heat, pathogens agglomerating gas gathers, and painful limbs arthralgia chiefly caused by damp pathogen person, all insufficiency of the spleen disease by heresy, spleen governing limbs thus also.Gallbladder be all dirty first of, 11 dirty all depend on gallbladder, and the vital essence of the five internal organs is all reported in spleen, therefore taken it for a long time, function settling five organs.
Os Draconis: Os Draconis be ancient times mammal as if the Skeletal Fossils of class, rhinoceros class, Hippocampal cortex etc..Nature and flavor: sweet, puckery are flat.Enter the heart, liver, kidney, large intestine channel.Effect: tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, stop blooding astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Controlling infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, stranguria with turbid discharge of passing out semen, and tells nosebleed and has blood in stool, and bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.Os Draconis matter weight, has the effect of good tranquillizing the mind by relieving convulsion, can use and controls various mind uneasiness, insomnia and dreamful sleep, tinnitus etc..
Concha Ostreae: for the shell of the long Concha Ostreae OstreagigasThunberg of Ostreidae animal, Dalian Bay Concha Ostreae OstreatalienwhanensisGrosse or Crassostrea rivularis OstrearivularisGould etc..Nature and flavor: salty, be slightly cold.Return liver, gallbladder, kidney channel.Effect: suppressing the hyperactive liver and subsiding YANG, hard masses softening and resolving, convergence are astringent or styptic treatment for spontaneous sweating.Research shows: Concha Ostreae is possibly together with vitamin B12, and this is that general food is lacked, and the brill element in vitamin B12 is the prevention indispensable material of pernicious anemia, thus Concha Ostreae has again the effect enlivening hemopoietic function.Concha Ostreae salty in the mouth, hard masses softening and resolving.With controlling the sucutaneous nodule of phlegm-fire pent-up, scrofula, the normal and compatibility such as Bulbus Fritillariae Thunbergii, Radix Scrophulariae.
Rhizoma Gastrodiae: for the dry tuber of orchid Rhizoma Gastrodiae GastrodiaelataBlume..Nature and flavor: sweet are flat.Return Liver Channel.Effect: suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.For dizziness of having a headache, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.Pharmaceutical research shows, Rhizoma Gastrodiae has significantly calm and anticonvulsant action.Rhizoma Gastrodiae is sweet flat, specially enters Liver Channel, function endogenous wind stopping relieving convulsion, and Gan Run is not strong, acts on gentle, and the panacea of endogenous wind for it can be used for treating the liver-wind stirring up internally caused by the various cause of disease, and infantile convulsion is twitched, though cold and heat and asthenia and sthenia, all can compatibility application.
Radix Glehniae: for the dry root of samphire glehnia littoralis GlehnialittoralisFr.SchmidtexMiq..Nature and flavor: hardship sweet, micro-, be slightly cold.Return lung, kidney channel.Effect: nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.Thirsty for lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound.Research display: Radix Glehniae does not only have the effect of antipyretic-antalgic, it is also possible to strengthen body immunity.
Radix Curcumae: for the dried root of zingiberaceous plant RADIX CURCUMAE CurcumawenyujinY.H.ChenetC.Ling, Rhizoma Curcumae Longae CurcumalongaL., Guangxi zedoary CurcumakwangsiensisS.G.LeeetC.F.Liang or Rhizoma Curcumae CurcumaphaeocaulisVal..Nature and flavor: pungent, bitter, cold.Return liver, the heart, lung meridian.Effect: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, removing heat from blood removing blood stasis with potent drugs.Cure mainly: the chest and abdomen side of body all pains of rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.The pungent scattered hardship of this product is let out, heat clearing away cold in nature, can have one's ideas straightened out by heart fire-clearing upset-relieving.Radix Curcumae pungent drugs can disperse and bitter drugs can descend, fragrance a surname reach, cold in nature again can heat clearing away.Both entered edema caused by disorder of QI with promoting QI circulation for relieving depression, entered again blood system with cooling blood and dissolving stasis, for the gas medicine in blood, for treating the chest pain of QI and blood stasis.
Carapax et Plastrum Testudinis: for sternite and the carapace of Testudinidae animal chinemysreevesii.Nature and flavor: become, sweet, be slightly cold.Return liver, kidney, heart channel.Effect: nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, Gu through only collapsing, reinforcing the heart of nourishing blood.Carapax et Plastrum Testudinis containing bone gelatin, hydrolysate containing several amino acids, protein, fat and calcium salt etc..Cure mainly hyperactivity of YANG due to deficiency of YIN, yin asthenia generating intrinsic heat, stirring-up of pathogenic wind in the interior resulting from deficiency.Suffer from a deficiency of the kidney the atrophic debility of bones, infantile metopism.Deficiency of YIN-blood, palpitation with fear, insomnia, forgetful.This product energy tonifying kidney-yin is appointed with Gu Chong, again heat clearing away cold in nature, and holding concurrently can cooling blood for hemostasis.For the menorrhagia of YinXuXueRe, metrorrhagia and metrostaxis.This product can nourish blood reinforcing the heart, can be used for insomnia forgetfulness.
The square solution of the present invention is: Flos Campsis promoting blood circulation by removing wind in side, Rhizoma Typhonii eliminates the phlegm arresting convulsion, Radix Ophiopogonis nourishing lung-YIN, clear away heart-fire relieving restlessness, Rhizoma Acori Graminei is had one's ideas straightened out eliminating phlegm, refreshment Fructus Alpiniae Oxyphyllae, Radix Achyranthis Bidentatae eliminating blood stasis and inducing menstruation, Fructus Ligustri Lucidi the kidney invigorating bone strengthening, Pheretima heat clearing away is calmed the frightened, above seven tastes are monarch drug altogether, most of medical instruments have the effect of arresting convulsion of eliminating the phlegm, refreshment Fructus Alpiniae Oxyphyllae on the one hand, and these effects can play the effect pacifying patient's irritability emotion so that the emotion of patient is easily controllable, reduce the fluctuation of patient's emotion, and then reach the purpose for the treatment of disease.nullFructus Viticis dispelling wind and heat pathogens、The clear profit head，Radix Salviae Miltiorrhizae removing heat from blood eliminating carbuncle、Clear away heart-fire relieving restlessness，Herba Schizonepetae expelling pathogenic wind from the body surface，Concha Margaritifera suppressing the hyperactive liver and subsiding YANG，Periostracum Cicadae dispelling wind and heat pathogens，Herba Dendrobii nourishing YIN and clearing away heat，Bombyx Batryticatus (parched) expelling wind to relieve convulsion，Above seven tastes are ministerial drug altogether，Ministerial drug first-selection has the effect of suppressing the hyperactive liver to relieve the wind syndrome，Enter Liver Channel，Can the clinical symptoms such as reduction of patient spasm，Also there is on the other hand the relieving restlessness that clears away heart-fire enrich blood the effect of easing the affected liver，Make the emotion of patient and attention can be controlled effectively，And then arrive the purpose for the treatment of disease，Radix Paeoniae Alba suppressing the hyperactive liver pain relieving、Yin fluid astringing receives antiperspirant，Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI、Ascending up spleen-Qi and Yang，Semen Platycladi tranquilizing by nourishing the heart，Semen Ziziphi Spinosae mind tranquilizing and the heart calming，Os Draconis tranquillizing and allaying excitement，Concha Ostreae suppressing the hyperactive liver and subsiding YANG，Rhizoma Gastrodiae suppressing the hyperactive liver to relieve the wind syndrome，Radix Glehniae nourishing YIN and clearing away lung-heat，Radix Curcumae regulating qi to disperse stagnation，Carapax et Plastrum Testudinis nourishing YIN for suppressing the hyperactive YANG、Kidney tonifying bone strengthening，Several tastes are adjuvant drug altogether above，Both monarch can have been coordinated、Minister strengthens nourishing the liver mind calming、Expelling wind to relieve convulsion、The effect of nourishing YIN for tranquillization，Monarch can also be restricted、Ministerial drug high strong，The health reducing drugs on patients causes further injury，The health to patient that adjuvant drug can make the efficacy of a drug mild is nursed one's health，Patient is made to recover gradually.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, have effect of eliminating phlegm of having one's ideas straightened out, the cleaning head, eliminate the phlegm arresting convulsion, tranquilizing by nourishing the heart, it is possible to effectively treat adult mild brain disturbance.
nullMedicine material consumption of the present invention is groped to sum up to draw through inventor in a large number，Each raw material dosage is for all to have good curative effect in following weight parts scope: Flos Campsis 7-17g、Rhizoma Typhonii 7-17g、Radix Ophiopogonis 10-20g、Rhizoma Acori Graminei 15-25g、Radix Achyranthis Bidentatae 13-23g、Fructus Ligustri Lucidi 10-20g、Pheretima 7-17g、Fructus Viticis 10-20g、Radix Salviae Miltiorrhizae 19-29g、Herba Schizonepetae 7-17g、Concha Margaritifera 19-29g、Periostracum Cicadae 3-9g、Herba Dendrobii 10-20g、Bombyx Batryticatus (parched) 7-17g、Radix Paeoniae Alba 10-20g、Radix Bupleuri 10-20g、Semen Platycladi 10-20g、Semen Ziziphi Spinosae 19-29g、Os Draconis 25-35g、Concha Ostreae 25-35g、Rhizoma Gastrodiae 10-20g、Radix Glehniae 15-25g、Radix Curcumae 10-20g、Carapax et Plastrum Testudinis 10-20g.
Wherein be preferably: Flos Campsis 12g, Rhizoma Typhonii 12g, Radix Ophiopogonis 15g, Rhizoma Acori Graminei 20g, Radix Achyranthis Bidentatae 18g, Fructus Ligustri Lucidi 15g, Pheretima 12g, Fructus Viticis 15g, Radix Salviae Miltiorrhizae 24g, Herba Schizonepetae 12g, Concha Margaritifera 24g, Periostracum Cicadae 6g, Herba Dendrobii 15g, Bombyx Batryticatus (parched) 12g, Radix Paeoniae Alba 15g, Radix Bupleuri 15g, Semen Platycladi 15g, Semen Ziziphi Spinosae 24g, Os Draconis 30g, Concha Ostreae 30g, Rhizoma Gastrodiae 15g, Radix Glehniae 20g, Radix Curcumae 15g, Carapax et Plastrum Testudinis 15g.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to prepare into any conventional oral preparations, such as pill, powder, tablet, oral liquid etc..These crude drug such as can be ground into powder mix homogeneously make powder and take after mixing it with water；Decocting can be used, through filtering to get filtrate, add preservative and make oral liquid；Can also directly take decoction if desired.
Currently preferred preparation method is granule, and its preparation method is as follows:
Step one: by weight proportion of the present invention, first becomes medicated bag by Fructus Ligustri Lucidi, Fructus Viticis, Semen Platycladi, Semen Ziziphi Spinosae bundle, is put in water and soaks about 45 minutes, filters, standby；
nullStep 2: by weight proportion of the present invention，By Concha Margaritifera、Os Draconis、Concha Ostreae、Carapax et Plastrum Testudinis is put into add in marmite and is remained cold water in step one after immersion，Exceed the water of powder 3-4 centimetre，After being fried boiling with high heat，Decoct 20～30 minutes with slow fire again，Filter，Obtain filtrate，Residue medicinal residues add the water of 2-3 centimetre，It is subsequently adding Rhizoma Typhonii、Radix Ophiopogonis、Rhizoma Acori Graminei、Radix Achyranthis Bidentatae、Radix Salviae Miltiorrhizae、The Radix Paeoniae Alba、Radix Glehniae、Radix Curcumae is put into and decocts about 45 minutes in pot，Add Herba Schizonepetae afterwards、Herba Dendrobii、Radix Bupleuri、Medicated bag in Rhizoma Gastrodiae and step one，Put into and pot continues decoct 30 minutes，It is eventually adding Flos Campsis to decoct 10 minutes，Filter，Obtain filtrate，When filtrate is concentrated into about 75 DEG C，Add 75% ethanol，Place precipitation，Filter，Abandon precipitation，Filtrate recycling ethanol，The thick paste of relative density 1.13～1.20 under 60 DEG C of environment；
Step 3: by weight proportion of the present invention, by Pheretima, Periostracum Cicadae, air-dry 200 mesh sieves that are crushed to of Bombyx Batryticatus (parched), standby；
Step 4: be uniformly mixed in step 3 gained fine powder addition step 2 gained thick paste, dry, pulverize into fine powder, adding appropriate Icing Sugar as diluent, ethanol as disintegrating agent, adopts dry granulation as wetting agent and microcrystalline Cellulose, make 10g/ bag, every bag of granule containing crude drug 5g.
Medicine of the present invention has effect of eliminating phlegm of having one's ideas straightened out, the cleaning head, eliminate the phlegm arresting convulsion, tranquilizing by nourishing the heart, and determined curative effect, cheap, safe ready, side effect is little, the mode that this Chinese medicine preparation adopts treat can release adult mild brain disturbance in the heart of physiology and on injury that patient is caused, reduce the injury that patient body is caused by Western medicine, also mitigate family burden simultaneously, according to clinical 160 example patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 85%, two the course for the treatment of total effective rate 95%.
Detailed description of the invention
Embodiment one, Flos Campsis 7g, Rhizoma Typhonii 7g, Radix Ophiopogonis 10g, Rhizoma Acori Graminei 15g, Radix Achyranthis Bidentatae 13g, Fructus Ligustri Lucidi 10g, Pheretima 7g, Fructus Viticis 10g, Radix Salviae Miltiorrhizae 19g, Herba Schizonepetae 7g, Concha Margaritifera 19g, Periostracum Cicadae 3g, Herba Dendrobii 10g, Bombyx Batryticatus (parched) 7g, Radix Paeoniae Alba 10g, Radix Bupleuri 10g, Semen Platycladi 10g, Semen Ziziphi Spinosae 19g, Os Draconis 25g, Concha Ostreae 25g, Rhizoma Gastrodiae 10g, Radix Glehniae 15g, Radix Curcumae 10g, Carapax et Plastrum Testudinis 10g.
Embodiment two, Flos Campsis 12g, Rhizoma Typhonii 12g, Radix Ophiopogonis 15g, Rhizoma Acori Graminei 20g, Radix Achyranthis Bidentatae 18g, Fructus Ligustri Lucidi 15g, Pheretima 12g, Fructus Viticis 15g, Radix Salviae Miltiorrhizae 24g, Herba Schizonepetae 12g, Concha Margaritifera 24g, Periostracum Cicadae 6g, Herba Dendrobii 15g, Bombyx Batryticatus (parched) 12g, Radix Paeoniae Alba 15g, Radix Bupleuri 15g, Semen Platycladi 15g, Semen Ziziphi Spinosae 24g, Os Draconis 30g, Concha Ostreae 30g, Rhizoma Gastrodiae 15g, Radix Glehniae 20g, Radix Curcumae 15g, Carapax et Plastrum Testudinis 15g.
Embodiment three, Flos Campsis 17g, Rhizoma Typhonii 17g, Radix Ophiopogonis 20g, Rhizoma Acori Graminei 25g, Radix Achyranthis Bidentatae 23g, Fructus Ligustri Lucidi 20g, Pheretima 17g, Fructus Viticis 20g, Radix Salviae Miltiorrhizae 29g, Herba Schizonepetae 17g, Concha Margaritifera 29g, Periostracum Cicadae 9g, Herba Dendrobii 20g, Bombyx Batryticatus (parched) 17g, Radix Paeoniae Alba 20g, Radix Bupleuri 20g, Semen Platycladi 20g, Semen Ziziphi Spinosae 29g, Os Draconis 35g, Concha Ostreae 35g, Rhizoma Gastrodiae 20g, Radix Glehniae 25g, Radix Curcumae 20g, Carapax et Plastrum Testudinis 20g.
Patient is presented herein below and uses the clinical statistics data of medicine of the present invention:
One, physical data
Accepting out-patient 160 example for medical treatment, wherein male 86 example, women 74 example, M-F 1.16: 1,30 years old mean age, the course of disease time is not etc..
Two, diagnostic criteria
1, learning difficulty companion is namely had to note in one's early years not lasting.
2, there are serious anxiety, depression or similar symptoms the manhood.
3, the improvement of highly significant is had by symptom after imipramine.
4, mental status inspection is characterized by that word speed speeds and theme is variable, but does not have obvious psychotic disease Thinking Characteristics.
Three, Therapeutic Method:
According to Medications Example two of the present invention, and the granule that preferred preparation method is made, boiled water is taken after mixing it with water, every day 3 times, each one bag, within 20 days, is a course for the treatment of.
Four, efficacy assessment standard:
1, curing: the clinical symptoms of adult mild brain disturbance, as impulsion, the symptom such as absent minded, nervous disappear substantially, every inspection is all normal；
2, effective: the clinical symptoms of adult mild brain disturbance, as impulsion, the symptom such as absent minded, nervous are controlled effectively, every inspection all takes a turn for the better to some extent；
3, invalid: clinical symptoms is not improved.
Five, therapeutic outcome statistics
Wherein: total effective rate=cure rate+improvement rate
According to statistical result showed, Chinese medicine of the present invention has good clinical effectiveness treatment adult mild brain disturbance, can be effectively improved the cure rate for the treatment of, is worth in clinical practice and promotes.
Model case and curative effect:
Case one, patient Zhang, man, 29 years old, patient's temper is got excited always very much, quarrel with others at the drop of a hat, and it is absent minded to do work, patient is through multiple hospitals inspection, finally it is diagnosed as adult mild brain disturbance, patient once repeatedly took Western medicine, but DeGrain, then the Therapeutic Method of Chinese medicine is adopted, adopt made preparation in the embodiment of the present invention two, and selected preparation method, after taking treatment a period of time, the situation of patient's impulsion improves, the attention time of staying increases to some extent, the state of an illness is eased, in order to consolidate curative effect, patient continues to have taken two courses for the treatment of, the symptom of patient is wholly absent, remove examination in hospital, indices all shows normally, without other uncomfortable phenomenons, recovery from illness.
Case two, patient Zhao, female, 28 years old, patient as a child just had the symptom of slight hyperkinetic syndrome, increase along with the age, the symptom of patient's hyperkinetic syndrome is alleviated to some extent, but in recent years, patient occurs absent minded, it is highly susceptible to interference, sometimes occur forever all carrying out something, or move individual ceaselessly symptom, patient removes examination in hospital, finally it is diagnosed as adult mild brain disturbance, patient wishes the Therapeutic Method adopting Chinese medicine, reduce the injury to health, adopt made preparation in the embodiment of the present invention two, and selected preparation method, after taking two courses for the treatment of, the attention of patient substantially gets a promotion, emotion also improves, for preventing recurrence, patient adheres to again having taken two courses for the treatment of, feel good, remove examination in hospital, indices all shows normally, health is without the symptom of any discomfort, recovery from illness.

Claims (4)

  1. null1. the Chinese medicine preparation treating adult mild brain disturbance，It is characterized in that，This Chinese medicine preparation is made up of the medicine of following weight portion: Flos Campsis 7-17g、Rhizoma Typhonii 7-17g、Radix Ophiopogonis 10-20g、Rhizoma Acori Graminei 15-25g、Radix Achyranthis Bidentatae 13-23g、Fructus Ligustri Lucidi 10-20g、Pheretima 7-17g、Fructus Viticis 10-20g、Radix Salviae Miltiorrhizae 19-29g、Herba Schizonepetae 7-17g、Concha Margaritifera 19-29g、Periostracum Cicadae 3-9g、Herba Dendrobii 10-20g、Bombyx Batryticatus (parched) 7-17g、Radix Paeoniae Alba 10-20g、Radix Bupleuri 10-20g、Semen Platycladi 10-20g、Semen Ziziphi Spinosae 19-29g、Os Draconis 25-35g、Concha Ostreae 25-35g、Rhizoma Gastrodiae 10-20g、Radix Glehniae 15-25g、Radix Curcumae 10-20g、Carapax et Plastrum Testudinis 10-20g.
  2. 2. the Chinese medicine preparation for the treatment of adult mild brain disturbance according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: Flos Campsis 12g, Rhizoma Typhonii 12g, Radix Ophiopogonis 15g, Rhizoma Acori Graminei 20g, Radix Achyranthis Bidentatae 18g, Fructus Ligustri Lucidi 15g, Pheretima 12g, Fructus Viticis 15g, Radix Salviae Miltiorrhizae 24g, Herba Schizonepetae 12g, Concha Margaritifera 24g, Periostracum Cicadae 6g, Herba Dendrobii 15g, Bombyx Batryticatus (parched) 12g, Radix Paeoniae Alba 15g, Radix Bupleuri 15g, Semen Platycladi 15g, Semen Ziziphi Spinosae 24g, Os Draconis 30g, Concha Ostreae 30g, Rhizoma Gastrodiae 15g, Radix Glehniae 20g, Radix Curcumae 15g, Carapax et Plastrum Testudinis 15g.
  3. 3. the Chinese medicine preparation for the treatment of adult mild brain disturbance according to claim 1 and 2, it is characterised in that: described Chinese medicine preparation is granule.
  4. 4. the preparation method of the Chinese medicine preparation treating adult mild brain disturbance, it is characterised in that preparation method is as follows: step one: by weight proportion of the present invention, first Fructus Ligustri Lucidi, Fructus Viticis, Semen Platycladi, Semen Ziziphi Spinosae bundle are become medicated bag, it is put in water and soaks about 45 minutes, filter, standby；nullStep 2: by weight proportion of the present invention，By Concha Margaritifera、Os Draconis、Concha Ostreae、Carapax et Plastrum Testudinis is put into add in marmite and is remained cold water in step one after immersion，Exceed the water of powder 3-4 centimetre，After being fried boiling with high heat，Decoct 20～30 minutes with slow fire again，Filter，Obtain filtrate，Residue medicinal residues add the water of 2-3 centimetre，It is subsequently adding Rhizoma Typhonii、Radix Ophiopogonis、Rhizoma Acori Graminei、Radix Achyranthis Bidentatae、Radix Salviae Miltiorrhizae、The Radix Paeoniae Alba、Radix Glehniae、Radix Curcumae is put into and decocts about 45 minutes in pot，Add Herba Schizonepetae afterwards、Herba Dendrobii、Radix Bupleuri、Medicated bag in Rhizoma Gastrodiae and step one，Put into and pot continues decoct 30 minutes，It is eventually adding Flos Campsis to decoct 10 minutes，Filter，Obtain filtrate，When filtrate is concentrated into about 75 DEG C，Add 75% ethanol，Place precipitation，Filter，Abandon precipitation，Filtrate recycling ethanol，The thick paste of relative density 1.13～1.20 under 60 DEG C of environment；Step 3: by weight proportion of the present invention, by Pheretima, Periostracum Cicadae, air-dry 200 mesh sieves that are crushed to of Bombyx Batryticatus (parched), standby；Step 4: be uniformly mixed in step 3 gained fine powder addition step 2 gained thick paste, dry, pulverize into fine powder, adding appropriate Icing Sugar as diluent, ethanol as disintegrating agent, adopts dry granulation as wetting agent and microcrystalline Cellulose, make 10g/ bag, every bag of granule containing crude drug 5g.
CN201610309015.5A 2016-05-04 2016-05-04 Traditional Chinese medicinal preparation for treating adult mild brain disturbance and preparation method of traditional Chinese medicinal preparation Withdrawn CN105770773A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115969911A (en) * 2023-03-20 2023-04-18 中国中医科学院中药研究所 Traditional Chinese medicine composition with anti-anxiety effect and preparation method and application thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101112510A (en) * 2007-07-10 2008-01-30 尹克华 Pearl soup Chinese traditional medicine for treating hyperkinetic symptom
CN104524464A (en) * 2014-12-30 2015-04-22 陈淑娟 Traditional Chinese medicine preparation for treating hyperactivity and preparation method of traditional Chinese medicine preparation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101112510A (en) * 2007-07-10 2008-01-30 尹克华 Pearl soup Chinese traditional medicine for treating hyperkinetic symptom
CN104524464A (en) * 2014-12-30 2015-04-22 陈淑娟 Traditional Chinese medicine preparation for treating hyperactivity and preparation method of traditional Chinese medicine preparation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115969911A (en) * 2023-03-20 2023-04-18 中国中医科学院中药研究所 Traditional Chinese medicine composition with anti-anxiety effect and preparation method and application thereof
CN115969911B (en) * 2023-03-20 2023-06-09 中国中医科学院中药研究所 Traditional Chinese medicine composition with anxiolytic effect and preparation method and application thereof

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Application publication date: 20160720