CN104873841A - Spleen strengthening and kidney nourishing pill for preventing and curing chronic renal failure and preparation method thereof - Google Patents

Spleen strengthening and kidney nourishing pill for preventing and curing chronic renal failure and preparation method thereof Download PDF

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CN104873841A
CN104873841A CN201510316511.9A CN201510316511A CN104873841A CN 104873841 A CN104873841 A CN 104873841A CN 201510316511 A CN201510316511 A CN 201510316511A CN 104873841 A CN104873841 A CN 104873841A
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polyporus
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张忠
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JINAN FANGYU CULTURE MEDIA Co Ltd
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JINAN FANGYU CULTURE MEDIA Co Ltd
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Abstract

The invention discloses a spleen strengthening and kidney nourishing pill for preventing and curing chronic renal failure. The spleen strengthening and kidney nourishing pill for preventing and curing chronic renal failure is prepared by the following main raw materials with weight proportion: 1-5 parts of herb pyrolae, 2-6 parts of radix aconiti carmichaeli, 4-10 parts of Chinese yam, 3-8 parts of dogwood, 2-4 parts of semen coicis, 1-3 parts of grifola, 6-10 parts of ginseng, 1-5 parts of herba epimedii, 10-20 parts of scabrous elephantfoot herb, 5-15 parts of poria cocos, 4-10 parts of circium japonicum, 10-20 parts of madder, 7-18 parts of semen raphani, 6-14 parts of semen cuscutae, 8-19 parts of astragalus membranaceus, and 5-7 parts of pericarpium citri reticulatae. The spleen strengthening and kidney nourishing pill has significant effect on uremia symptoms, not only has the efficacies of nourishing kidney and promoting urination, but also can coordinate viscera dysfunction of uremia form the source, and has favorable recovering and coordinating functions for people with mental fatigue and exhausted expressions caused by long illness. The spleen strengthening and kidney nourishing pill mainly chooses local common medicinal materials which are low in prices, so that the economical burden of patients is reduced.

Description

A kind of strengthening spleen, tonifying kidney pill preventing and treating chronic renal failure and preparation method thereof
Technical field
The invention belongs to traditional Chinese medicine field, especially relate to a kind of strengthening spleen, tonifying kidney pill preventing and treating chronic renal failure and preparation method thereof.
Background technology
Chronic renal failure (CRF) is also known as chronic renal insufficiency, refer to the chronic progressive external Renal lesion that a variety of causes causes, cause the obvious atrophy of kidney, its basic function can not be maintained, clinical appearance is with metabolite retention, water, electrolyte, acid base imbalance, each system involvement of whole body is the clinical syndrome of main manifestations, also referred to as chronic renal failure.From protopathy onset to renal insufficiency, can be the several years interval time to more than ten years.Chronic renal failure is the severe stage of renal insufficiency.The cause of disease: the cause of disease of chronic renal failure accounts for first place with various constitutional and secondary glomerulonephritis, secondly be that congenital urinary system malformation is (as renal hypoplasia, congenital polycystic kidney, vesicoureteral reflux etc.), hereditary is (as hereditary nephritis, medullary cystic disease of kidney, Fanconi syndrome etc.) in general systemic disease with renal arteriolosclerosis, hypertension, connective tissue diseases etc. are common, in recent years, the protopathy of CRF changes to some extent, renal interstitial tubule damages the CRF caused and is also subject to people's attention gradually, diabetic nephropathy, autoimmunity and connective tissue disease renal damage, the CRF caused is also on the rise.Clinical manifestation: chronic renal failure has influence on each organs and systems, diversified clinical manifestation can be caused, but, before the nephronloss of 80%, or before GFP drops to 25ml/ minute, without any symptom or little biochemical change can be only had, in the chronic progressive diseases such as such as polycystic kidney, even if GFR is lower than 10ml/ minute, also can not have symptom, this is caused by the huge adaptation of remaining nephron.Chronic renal failure mainly causes following various clinical pathological changes late period: 1. water, electrolyte, acid base imbalance: namely the basic function of kidney regulates water, electrolyte, acid-base balance, during renal insufficiency, due to its excretion or metabolic dysfunction, water in various degree will inevitably be caused, electrolyte, acid base imbalance, but, different with ARF, CRF in its very long course of disease due to the various compensatory mechanism of body, these metabolism disorders seem not fairly obvious sometimes, in fact, when light moderate CRF, the kidney losing partial function still more fully discharges the material or refuse that produce in various exogenous absorption and body, when normal renal function loses about 70%, generally only there will be part water, electrolyte, acid base imbalance, only have when renal function declines further, and take in or produce too much water in body, electrolyte, acid or alkaline matter just there will be obvious clinical manifestation.2. sugar, fat, protein and disorder of amino acid catabolism.3. each system dysfunction: 1. digestive system; 2. cardiovascular system; 3. respiratory system; 4. nervous system; 5. blood system; 6. motor system; 7. change of skin; 8. immune system; , all there is obstacle in various degree in 9. hormonal system.
In the method for existing treatment chronic renal failure, Authorization Notice No. CN 102688414 B(application number 201210210548.X) disclose a kind of Chinese medicine strengthening spleen, tonifying kidney pill granule for the treatment of chronic renal failure complication of hemodialysis, it is characterized in that: described Chinese medicine strengthening spleen, tonifying kidney pill granule is only made up of as crude drug the Radix Astragali, Radix Ginseng, Rhizoma Dioscoreae, Semen Coicis, Flos Carthami, Polyporus, Herba Orostachyos, Herba Dendrobii, Arillus Longan, Herba Taraxaci, Radix Angelicae Sinensis, the Fructus Kochiae, Thallus Laminariae (Thallus Eckloniae), Herba Leonuri, Radix Salviae Miltiorrhizae, Radix Phytolaccae, Radix Morindae Officinalis, Coriolous Dersicolor (Fr.) Quel, Fructus Psoraleae and Radix Aconiti Lateralis Preparata, Authorization Notice No. CN 102716339 B(application number 201210224055.1) patent discloses a kind of Chinese medicine strengthening spleen, tonifying kidney pill coordinating hemodialysis chronic renal failure, it is characterized in that, in described Chinese medicine strengthening spleen, tonifying kidney pill, the weight portion of each component is: Herba Cissampelotis pareiae 10-20 weight portion, Radix Glehniae 20-30 weight portion, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 weight portion, the Radix Paeoniae Alba 25-35 weight portion, Concha Ostreae 10-20 weight portion, Herba Ecliptae 30-40 weight portion, Cortex Dictamni 10-20 weight portion, Radix Rehmanniae Preparata 20-30 weight portion, Flos Chrysanthemi 15-25 weight portion, Rhizoma Chuanxiong 20-30 weight portion, Herba Plantaginis 10-20 weight portion, Folium Pyrrosiae 10-20 weight portion, Radix Ophiopogonis 30-40 weight portion, Fructus Lycii 25-35 weight portion, Herba Epimedii 10-20 weight portion, Polyporus 60-70 weight portion, Herba Schizonepetae 10-20 weight portion, Natrii Sulfas 15-25 weight portion, Caulis Spatholobi 25-35 weight portion and Poria 30-40 weight portion.
As can be seen here: Chinese medicine chronic renal failure can prevent and treat clinical symptoms, protection residual renal function, delays PD, postpones the time must dialysed with renal transplantation, is more and more subject to the attention of domestic and international medical circle.Chronic renal failure belongs to Chinese medicine obstruction and rejection, edema, the categories such as poison, asthenia of drowning, Chinese medicine thinks that with the passing of time this disease delays or exopathogen invasion and attack, overstrain internal injury, cause function deficient, turbid damp is stopped over, three Jiao of being jammed, ascending or descending movement of vital Qi is not normal, though the state of an illness is critical, syndrome is complicated, and deficiency in origin and excess in superficiality runs through course of disease main pathogenesis all the time.Deficiency in origin is based on spleen kidney yang (gas) void, and mark is real in turbid damp, noxious water, blood stasis, and strengthening vital QI to eliminate pathogenic factors is answered in treatment.
Summary of the invention
For the present situation of the medicine deficiency of existing control chronic renal failure, an object of the present invention is to provide a kind of strengthening spleen, tonifying kidney pill preventing and treating chronic renal failure fast and effectively, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned strengthening spleen, tonifying kidney pill.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Prevent and treat a strengthening spleen, tonifying kidney pill for chronic renal failure, take off the primary raw material stating weight proportion and be prepared from: Herba Pyrolae 1-5 part, Radix Aconiti Lateralis Preparata 2-6 part, Rhizoma Dioscoreae 4-10 part, Fructus Corni 3-8 part, Semen Coicis 2-4 part, Polyporus 1-3 part, Radix Ginseng 6-10 part, Herba Epimedii 1-5 part, Scabrous Elephantfoot Herb 10-20 part, Poria 5-15 part, Radix Cirsii Japonici 4-10 part, Radix Rubiae 10-20 part, Semen Raphani 7-18 part, Semen Cuscutae 6-14 part, Radix Astragali 8-19 part, Pericarpium Citri Reticulatae 5-7 part.
Prevent and treat a strengthening spleen, tonifying kidney pill for chronic renal failure, preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Herba Pyrolae 2-4 part, Radix Aconiti Lateralis Preparata 3-5 part, Rhizoma Dioscoreae 6-8 part, Fructus Corni 5-7 part, Semen Coicis 2.5-3.5 part, Polyporus 1.5-2.5 part, Radix Ginseng 7-9 part, Herba Epimedii 2-4 part, Scabrous Elephantfoot Herb 13-18 part, Poria 8-13 part, Radix Cirsii Japonici 6-8 part, Radix Rubiae 13-18 part, Semen Raphani 10-15 part, Semen Cuscutae 8-12 part, Radix Astragali 12-17 part, Pericarpium Citri Reticulatae 5.5-6.5 part.
Prevent and treat a strengthening spleen, tonifying kidney pill for chronic renal failure, better preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Herba Pyrolae 3 parts, Radix Aconiti Lateralis Preparata 4 parts, Rhizoma Dioscoreae 7 parts, Fructus Corni 6 parts, Semen Coicis 3 parts, Polyporus 2 parts, Radix Ginseng 8 parts, Herba Epimedii 3 parts, Scabrous Elephantfoot Herb 15 parts, 10 parts, Poria, Radix Cirsii Japonici 7 parts, 15 parts, Radix Rubiae, Semen Raphani 12 parts, Semen Cuscutae 10 parts, the Radix Astragali 14 parts, Pericarpium Citri Reticulatae 6 parts.
The preparation process of above-mentioned control chronic renal failure strengthening spleen, tonifying kidney pill is as follows:
1. Pericarpium Citri Reticulatae and Polyporus are cleaned, be placed in shady and cool ventilation place and dry, after smashing to pieces, put into crock, add yellow wine, slightly stewing 1-3 hour, obtains wine Pericarpium Citri Reticulatae and Polyporus, is placed in by wheat bran in dry pot, by sliding for wheat bran parch sharp state, drop into wine Pericarpium Citri Reticulatae and Polyporus, stir-fry 3-8 minute repeatedly, ceases fire, sieve removes wheat bran, and the Pericarpium Citri Reticulatae good by parch and Polyporus are dried in the air and coolly grind to form smalls to cross 80-120 mesh sieve stand-by;
2. removed the peel by Rhizoma Dioscoreae, together clean, be cut into the block of beans size, be placed on food steamer with Semen Raphani, heating 10-20 minute, within slightly stewing 10 minutes, take out, be laid on the upper little fire of clean iron plate and dry 5-10 minute slowly, take out and dry in the air cool to room temperature, it is stand-by to grind to form smalls;
3. Herba Pyrolae, Radix Aconiti Lateralis Preparata, Scabrous Elephantfoot Herb, Radix Ginseng and Radix Rubiae are cleaned, smash, dryouied by hot pot, drop into the crude drug handled well, stir-fry 2-6 minute repeatedly, dries in the air to room temperature, and it is stand-by to grind to form smalls;
4. by Fructus Corni, Semen Coicis, Herba Epimedii, Poria, Radix Cirsii Japonici, Semen Cuscutae and the Radix Astragali water soaking 50-70 minute with 50-70 DEG C, be placed in marmite and decoct with water 20-50 minute, water consumption is 2-4 times of crude drug gross weight, filters to get filtrate;
5. by step 1.-3. gained smalls and step 4. gained filtrate mix, fully stir after 5-10 minute and add Mel, rapid stirring becomes thick paste, thick paste is dried 10-30 minute, obtain drying object, drying object is made circle according to the preparation for processing of pill, packs and get final product.
The preparation method of above-mentioned strengthening spleen, tonifying kidney pill, 1. step adds yellow wine, slightly stewing 1.5-2.5 hour (preferably adding yellow wine, slightly stewing 2 hours).
The preparation method of above-mentioned strengthening spleen, tonifying kidney pill, 1. step drops into wine Pericarpium Citri Reticulatae and Polyporus, and stir-fry 5-7 minute (preferably drop into wine Pericarpium Citri Reticulatae and Polyporus, repeatedly stir-fry 6 minutes) repeatedly.
The preparation method of above-mentioned strengthening spleen, tonifying kidney pill, 2. step is placed on food steamer, heating 13-18 minute, slightly within stewing 10 minutes, take out, be laid on the upper little fire of clean iron plate to dry slowly and (be preferably placed on food steamer for 6-9 minute, heat 15 minutes, slightly within stewing 10 minutes, take out, be laid on the upper little fire of clean iron plate and dry 7 minutes slowly).
The preparation method of above-mentioned strengthening spleen, tonifying kidney pill, 3. step drops into the crude drug handled well, and stir-fry 3-5 minute repeatedly, dries in the air to room temperature (preferably drop into the crude drug handled well, repeatedly stir-fry 4 minutes, dry in the air to room temperature).
The preparation method of above-mentioned strengthening spleen, tonifying kidney pill, step is 4. by Fructus Corni, Semen Coicis, Herba Epimedii, Poria, Radix Cirsii Japonici, Semen Cuscutae and the Radix Astragali water soaking 55-65 minute with 55-65 DEG C, be placed in marmite and decoct with water 30-40 minute, water consumption is that the 2.5-3.5 of crude drug gross weight is doubly (preferably by Fructus Corni, Semen Coicis, Herba Epimedii, Poria, Radix Cirsii Japonici, Semen Cuscutae and the Radix Astragali water soaking 60 minutes with 60 DEG C, be placed in marmite and decoct with water 35 minutes, water consumption is 3 times of crude drug gross weight).
The preparation method of above-mentioned strengthening spleen, tonifying kidney pill, 5. step fully stirs after 6-9 minute and adds Mel, and rapid stirring becomes thick paste, is dried by thick paste 15-25 minute (preferably fully stir after 8 minutes and add Mel, rapid stirring becomes thick paste, thick paste is dried 20 minutes).
Using method: for making strengthening spleen, tonifying kidney pill of the present invention reach optimum therapeuticing effect, every day three times, half an hour takes after breakfast, lunch and dinner, gets 1-3 grain at every turn, uses warm water delivery service.
This strengthening spleen, tonifying kidney pill is to the Be very effective of chronic renal failure symptom, not only there is effect of the kidney invigorating, diuresis, can also nurse one's health the viscera function disorder of chronic renal failure from root, cause lethargy for prolonged illness, look tired person has good recovery and opsonic action.The local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Herba Pyrolae: Herba pyrolae japonicae water decoction is to staphylococcus aureus, Hemolytic streptococcus, streptococcus pneumoniae, meningococcus, shigella flexneri, Bacillus typhi and bacillus pyocyaneus etc. have inhibitory action, Pyrolin against Staphylococcus aureus, Bacillus typhi, bacillus pyocyaneus, Bacillus proteus, sonne bacillus and escherichia coli also all have inhibitory action, its MIC is respectively: 12.5, 12.5-50, 20-50, 50 and 100mcg/ml, Herba pyrolae japonicae can significantly improve body tissue cAMP content and histoorgan blood flow, improve and organize carbohydrate metabolism enzyme element active promotion cellular energy metabolism, renal blood flow is increased, microcirculation improves.In Herba pyrolae japonicae, chemical composition oleanolic acid has hepatoprotective to use, and has significant protective effect to the acute liver that CCI4 causes, and can promote liver cell regeneration, and ursolic acid can reduce serum transaminase.In addition, oleanolic acid and pyrolatin also have diuresis, tonify deficiency, kidney tonifying, expelling wind and removing dampness, promoting blood flow to regulate menstruation, control weak cough, over-strained hemoptysis, rheumatic arthritis, metrorrhagia, leucorrhea, traumatic hemorrhage.
Radix Aconiti Lateralis Preparata: excess of YIN due to YANG-insufficiency, real cold with pseudo-heat.Overabundance of YANG leading to deficiency of YIN, real heat with pseudo-cold and anemia of pregnant woman all prohibit clothes.Radix Aconiti Lateralis Preparata dietary function: Radix Aconiti Lateralis Preparata acrid in the mouth, sweet, hot in nature; Poisonous; GUIXIN, spleen, kidney channel; Gas hero row is loose, can rise and can fall, and walks and does not keep and have that to mend fire supporing yang, the cold dehumidifying of green bristlegrass, pain relieving cures mainly YANG-depletion for de-, cold extremities faint pulse, sexual impotence cold womb, cold limbs has a headache, YIN-fire sore throat, trusted subordinate's cold type of pain, vomiting and diarrhoea chronic dysentery, cold junction constipation, YIN-cold edema, cold long-pending hernia abdominal mass, yang deficiency diseases caused by exogenous pathogenic factor, anemofrigid-damp arthralgia, apoplexy contraction is anxious, and carbuncle of yin nature skin ulcer is leaked.
Rhizoma Dioscoreae: invigorating spleen and reinforcing stomach.Aid digestion: contained by Rhizoma Dioscoreae can diastatic diastase, be 3 times of content in Radix Raphani, edible during flatulence, there is the effect of facilitating digestion, can remove malaise symptoms, be conducive to improving taste digestive and absorptive functions, be the good merchantable brand of the medicine-food two-purpose of flat tonifying the spleen and stomach simply; Kidney nourishing and replenishing vital essence: Rhizoma Dioscoreae contains mucoprotein, the material such as amylase, saponin, free amino acid, polyphenol oxidase, and content comparatively horn of plenty, having tonic effect, is the good merchantable brand of the rehabilitation tonic after being ill, has the effect of strong body, kidney nourishing and replenishing vital essence; Lung benefiting cough-relieving: Rhizoma Dioscoreae contains saponin, lymphatic temperament, has lubrication, moist effect, thus can lung benefiting gas, support lung yin, the disease for the treatment of deficiency of the lung phlegmatic cough chronic cough; Prevention cardiovascular diseases: Rhizoma Dioscoreae is fatty hardly, and the contained mucoprotein lipidosis that can prevent cardiovascular system, prevents tremulous pulse from hardening prematurely.Rhizoma Dioscoreae contains saponin can reduce cholesterol and triglyceride, is improved effect to the disease such as hypertension and hyperlipidemia; Life lengthening: Rhizoma Dioscoreae can increase T lymphocytes in human body, strengthens immunologic function, delaying cell aging; Anti-hepatic coma: the choline contained by Rhizoma Dioscoreae is the transmitter substance relevant with learning and memory---the material base of acetylcholine, research finds that Rhizoma Dioscoreae has sedation, can resist hepatic coma; Defatting beauty: Rhizoma Dioscoreae contains various trace elements, abundant vitamin and mineral, and especially the content of potassium is higher, institute's heat content is relatively low again, often eats, and has the effect of defatting beauty.
Fructus Corni: liver and kidney tonifying; Convergence is solid de-.Cure mainly and have a dizzy spell; Deafness and tinnitus; Soreness of the waist and knees; Emission and spermatorrhea; Frequent micturition; Fructus Corni incessant sweating due to debility; Woman uterine bleeding; Interior-heat is quenched one's thirst; Warming the liver the kidney invigorating, except a wind cutting, only menorrhagia, controls senile frequent micturition.
Semen Coicis: Semen Coicis, Chinese medicine, another name Semen Coicis, NLIUGU, Semen Coicis, the Fructus Sapindi Mukouossi.For the kernel of grass Semen Coicis Coix lacryma-jobi L. var. meyuan (Romen.) Stapf.There is spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal.For effect of edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.
Polyporus: economic worth: edible when sporophore children is tender, taste is very delicious.Its underground sclerotium black, various shapes are famous Chinese medicine, have diuresis to harness the river swollen effect.Containing polyporusum bellatus (glucan), test anticancer.
Radix Ginseng: effect: strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung, promotes the production of body fluid, and calms the nerves.Cure mainly: weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, prolonged illness weakness with emaciation, palpitation with fear insomnia, sexual impotence cold womb; Heart failure, cardiogenic shock.For dyspnea with shortness of breath, palpitation and amnesia, thirsty hyperhidrosis, lack of appetite is unable, all acute and chronic diseases and the shock caused after losing blood, collapse.Strongly invigorating primordial QI, promotes the production of body fluid Gu de-, calms the nerves.Control impairment caused by overstrain deficient, lack of appetite, asthenia, food is told in regurgitation, stool lingering diarrhea, and empty cough with asthma is urged, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, and frequent micturition, quenches one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion, and prolonged deficiency is not multiple, the card of all qi-blood-body fluid deficiencies.
Herba Epimedii: cure mainly impotence and premature ejaculation, pain in the low back and legs, numb limbs and tense tendons, hemiplegia, neurasthenia, forgetful, tinnitus, dizzy disease such as grade.Herba Epimedii is Chinese conventional Chinese medicine.Function cures mainly: kidney invigorating and YANG supporting, expelling wind and removing dampness.Control sexual impotence erectile problem, hemiplegia is unsuccessful, dribbling urination, and muscles and bones contraction is anxious, and cough, optic atrohic blindness after being ill, toothache caused by fire of deficiency type, hemiplegia, weakness of the waist and knees, rheumatic arthralgia, extremity are meciless.Scabrous Elephantfoot Herb: all herbal medicine, has effect of heat-clearing and toxic substances removing, swelling diuretic, cures cold, the disease such as bacillary dysentery, gastroenteritis, tonsillitis, pharyngolaryngitis, oedema due to nephritis, conjunctivitis, furuncle and phyma, is traditional Chinese medical science common medicine.
The Radix Astragali: the Radix Astragali has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contraction, regulate blood sugar content.The Radix Astragali can not only coronary artery dilator, improves blood supply of cardiac muscle, improves immunologic function, and can the process of delaying cell aging.
Poria: sweet in the mouth, light, property is put down.Return through GUIXIN, lung, spleen, kidney channel.Effect promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.
Cure mainly for edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix Cirsii Japonici: sweet, bitter, cold.Return through GUIXIN, Liver Channel.Effect cooling blood for hemostasis, removing blood stasis to reduce swelling.Cure mainly for epistaxis, spit blood, hematuria, has blood in stool, metrorrhagia, traumatic hemorrhage, carbuncle sore tumefacting virus.
Radix Rubiae: removing heat from blood and promoting blood circulation, blood stasis dispelling, stimulates the menstrual flow.For haematemesis, epistaxis, metrostaxis, traumatic hemorrhage, amenorrhea stasis blocking, arthralgia, tumbling and swelling.Cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling: this product is stopped blooding and do not stay the stasis of blood, amenorrhea stomachache, traumatic injury hemorrhage for heat syndrome.
Semen Raphani: pungent, sweet, flat.Gui Jing returns lung, spleen, stomach warp.Effect helps digestion de-swelling, lowering the adverse-rising QI to resolve phlegm.Cure mainly for retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant heap soil or fertilizer over and around the roots is breathed with cough.
Semen Cuscutae: base is former: be the herb of Convolvulaceae Hellweed Semen Cuscutae.Composition: Semen Cuscutae is containing alkaloid, anthraquinone, coumarin, flavone, glycoside, sterol, tannic acid, saccharide etc.Flavonoid has: Quercetin, astragalin, hyperin; Sterols has: cholesterol, campesterol, cupreol, stigmasterol, β-Amyrin.Also trace element is contained as strontium, molybdenum, calcium, magnesium, ferrum, manganese, zinc, copper etc. and several amino acids (free amino acid in seed and the total amino acids after being hydrolyzed are 5.3%, and wherein the content of essential amino acids accounts for 42.8%).The property of medicine: micro-pungent, sweet, flat, nontoxic.Function cures mainly: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.The waist knee joint muscles and bones being applicable to deficiency of the liver and kindey is ached, the diseases such as legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf and women's leukorrhagia, habitual abortion.
Pericarpium Citri Reticulatae: bitter in the mouth, pungent, warm in nature.Gui Jing returns lung, spleen channel.Effect regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Cure mainly for distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
Strengthening spleen, tonifying kidney pill of the present invention is based on the principle of Chinese medicine control chronic renal failure.The medical material selected all has effect of strengthening spleen, tonifying kidney, diuresis, for chronic renal failure symptom, starts with from root, belongs to the prescription for the treatment of both the principal and secondary aspects of a disease.Fabulous therapeutical effect is had to chronic renal failure.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1the strengthening spleen, tonifying kidney pill of control chronic renal failure, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Pyrolae 1 part, Radix Aconiti Lateralis Preparata 2 parts, Rhizoma Dioscoreae 4 parts, Fructus Corni 3 parts, Semen Coicis 2 parts, Polyporus 1 part, Radix Ginseng 6 parts, Herba Epimedii 1 part, Scabrous Elephantfoot Herb 10 parts, 5 parts, Poria, Radix Cirsii Japonici 4 parts, 10 parts, Radix Rubiae, Semen Raphani 7 parts, Semen Cuscutae 6 parts, the Radix Astragali 8 parts, Pericarpium Citri Reticulatae 5 parts.
The strengthening spleen, tonifying kidney pill of above-mentioned control chronic renal failure, preparation process is as follows:
1. Pericarpium Citri Reticulatae and Polyporus are cleaned, be placed in shady and cool ventilation place and dry, after smashing to pieces, put into crock, add yellow wine, slightly stewing 1 hour, obtain wine Pericarpium Citri Reticulatae and Polyporus, wheat bran is placed in dry pot, by sliding for wheat bran parch sharp state, drop into wine Pericarpium Citri Reticulatae and Polyporus, repeatedly stir-fry 3 minutes, cease fire, sieve removes wheat bran, and the Pericarpium Citri Reticulatae good by parch and Polyporus are dried in the air and coolly grind to form smalls to cross 80 mesh sieves stand-by;
2. removed the peel by Rhizoma Dioscoreae, together clean, be cut into the block of beans size, be placed on food steamer, heat 10 minutes with Semen Raphani, within slightly stewing 10 minutes, take out, be laid on the upper little fire of clean iron plate and dry 5 minutes slowly, taking-up is dried in the air cool to room temperature, and it is stand-by to grind to form smalls;
3. Herba Pyrolae, Radix Aconiti Lateralis Preparata, Scabrous Elephantfoot Herb, Radix Ginseng and Radix Rubiae are cleaned, smash, dryouied by hot pot, drop into the crude drug handled well, repeatedly stir-fry 2 minutes, dry in the air to room temperature, it is stand-by to grind to form smalls;
4. by Fructus Corni, Semen Coicis, Herba Epimedii, Poria, Radix Cirsii Japonici, Semen Cuscutae and the Radix Astragali water soaking 50 minutes with 50 DEG C, be placed in marmite and decoct with water 20 minutes, water consumption is 2 times of crude drug gross weight, filters to get filtrate;
5. by step 1.-3. gained smalls and step 4. gained filtrate mix, fully stir after 5 minutes and add Mel, rapid stirring becomes thick paste, thick paste is dried 10 minutes, obtains drying object, and drying object is made circle according to the preparation for processing of pill, packs and get final product.
model case one:king XX, female, 48 years old, Beijing personage.Autumn in 2013, patient examined, patient's readme: patient's readme always feels general weakness recently, was reluctant conation, and the straight of pain in the lumbar region does not get up, also anorexia, even if having some reluctantly, also can be difficult to digestion, all dare not drink water more in the evening, the existing time more than 1 year.1 year with examination in hospital of making a return journey after more than once, ate a lot of Chinese medicine and western medicine all without positive effect, and started to take strengthening spleen, tonifying kidney pill of the present invention under the suggestion of doctor.
Take the present embodiment 1 gained strengthening spleen, tonifying kidney pill, every day three times, after breakfast, lunch and dinner, half an hour takes, and gets 1 at every turn, uses warm water delivery service.Take 7 days, the symptom of soreness of waist pain in the lumbar region alleviates; Take 1 month, whole body has strength, and also do not got up in the night to urinate in the evening, and continue to take 2 months, malaise symptoms disappears completely, and patient's self-induction is hale and hearty.
embodiment 2the strengthening spleen, tonifying kidney pill of control chronic renal failure, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Pyrolae 5 parts, Radix Aconiti Lateralis Preparata 6 parts, Rhizoma Dioscoreae 10 parts, Fructus Corni 8 parts, Semen Coicis 4 parts, Polyporus 3 parts, Radix Ginseng 10 parts, Herba Epimedii 5 parts, Scabrous Elephantfoot Herb 20 parts, 15 parts, Poria, Radix Cirsii Japonici 10 parts, 20 parts, Radix Rubiae, Semen Raphani 18 parts, Semen Cuscutae 14 parts, the Radix Astragali 19 parts, Pericarpium Citri Reticulatae 7 parts.
The strengthening spleen, tonifying kidney pill of above-mentioned control chronic renal failure, preparation process is as follows:
1. Pericarpium Citri Reticulatae and Polyporus are cleaned, be placed in shady and cool ventilation place and dry, after smashing to pieces, put into crock, add yellow wine, slightly stewing 3 hours, obtain wine Pericarpium Citri Reticulatae and Polyporus, wheat bran is placed in dry pot, by sliding for wheat bran parch sharp state, drop into wine Pericarpium Citri Reticulatae and Polyporus, repeatedly stir-fry 8 minutes, cease fire, sieve removes wheat bran, and the Pericarpium Citri Reticulatae good by parch and Polyporus are dried in the air and coolly grind to form smalls to cross 120 mesh sieves stand-by;
2. removed the peel by Rhizoma Dioscoreae, together clean, be cut into the block of beans size, be placed on food steamer, heat 20 minutes with Semen Raphani, within slightly stewing 10 minutes, take out, be laid on the upper little fire of clean iron plate and dry 10 minutes slowly, taking-up is dried in the air cool to room temperature, and it is stand-by to grind to form smalls;
3. Herba Pyrolae, Radix Aconiti Lateralis Preparata, Scabrous Elephantfoot Herb, Radix Ginseng and Radix Rubiae are cleaned, smash, dryouied by hot pot, drop into the crude drug handled well, repeatedly stir-fry 6 minutes, dry in the air to room temperature, it is stand-by to grind to form smalls;
4. by Fructus Corni, Semen Coicis, Herba Epimedii, Poria, Radix Cirsii Japonici, Semen Cuscutae and the Radix Astragali water soaking 70 minutes with 70 DEG C, be placed in marmite and decoct with water 50 minutes, water consumption is 4 times of crude drug gross weight, filters to get filtrate;
5. by step 1.-3. gained smalls and step 4. gained filtrate mix, fully stir after 10 minutes and add Mel, rapid stirring becomes thick paste, thick paste is dried 30 minutes, obtains drying object, and drying object is made circle according to the preparation for processing of pill, packs and get final product.
embodiment 3the strengthening spleen, tonifying kidney pill of control chronic renal failure, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Pyrolae 2 parts, Radix Aconiti Lateralis Preparata 3 parts, Rhizoma Dioscoreae 6 parts, Fructus Corni 5 parts, Semen Coicis 2.5 parts, Polyporus 1.5 parts, Radix Ginseng 7 parts, Herba Epimedii 2 parts, Scabrous Elephantfoot Herb 13 parts, 8 parts, Poria, Radix Cirsii Japonici 6 parts, 13 parts, Radix Rubiae, Semen Raphani 10 parts, Semen Cuscutae 8 parts, the Radix Astragali 12 parts, Pericarpium Citri Reticulatae 5.5 parts.
The strengthening spleen, tonifying kidney pill of above-mentioned control chronic renal failure, preparation process is as follows:
1. Pericarpium Citri Reticulatae and Polyporus are cleaned, be placed in shady and cool ventilation place and dry, after smashing to pieces, put into crock, add yellow wine, slightly stewing 1.5 hours, obtain wine Pericarpium Citri Reticulatae and Polyporus, wheat bran is placed in dry pot, by sliding for wheat bran parch sharp state, drop into wine Pericarpium Citri Reticulatae and Polyporus, repeatedly stir-fry 5 minutes, cease fire, sieve removes wheat bran, and the Pericarpium Citri Reticulatae good by parch and Polyporus are dried in the air and coolly grind to form smalls to cross 90 mesh sieves stand-by;
2. removed the peel by Rhizoma Dioscoreae, together clean, be cut into the block of beans size, be placed on food steamer, heat 13 minutes with Semen Raphani, within slightly stewing 10 minutes, take out, be laid on the upper little fire of clean iron plate and dry 6 minutes slowly, taking-up is dried in the air cool to room temperature, and it is stand-by to grind to form smalls;
3. Herba Pyrolae, Radix Aconiti Lateralis Preparata, Scabrous Elephantfoot Herb, Radix Ginseng and Radix Rubiae are cleaned, smash, dryouied by hot pot, drop into the crude drug handled well, repeatedly stir-fry 3 minutes, dry in the air to room temperature, it is stand-by to grind to form smalls;
4. by Fructus Corni, Semen Coicis, Herba Epimedii, Poria, Radix Cirsii Japonici, Semen Cuscutae and the Radix Astragali water soaking 55 minutes with 55 DEG C, be placed in marmite and decoct with water 30 minutes, water consumption is 2.5 times of crude drug gross weight, filters to get filtrate;
5. by step 1.-3. gained smalls and step 4. gained filtrate mix, fully stir after 6 minutes and add Mel, rapid stirring becomes thick paste, thick paste is dried 15 minutes, obtains drying object, and drying object is made circle according to the preparation for processing of pill, packs and get final product.
model case two:woods XX, man, 50 years old, Chengyang District, Qingdao of Shandong province.Be engaged in accountancy always, symptom: patient's readme occurred before half a year that the mental status is not good, always have a sleepless night in the evening, the work symptom such as out of spirits, moreover patient have also appeared the phenomenon of amenorrhea nearest half a year, originally thinks it is age to amenorrhea, examines the time: on April 12nd, 2012, because patient does not like by Drug therapy, so doctor advised takes strengthening spleen, tonifying kidney pill of the present invention.
Take the present embodiment 3 gained strengthening spleen, tonifying kidney pill, every day three times, after breakfast, lunch and dinner, half an hour takes, and gets 2 at every turn, uses warm water delivery service.Take 10 days, the mental status is good, and sleep quality improves; Take 1 month, menstruation recovery is normal; Continue to take 2 months, malaise symptoms disappears completely.
embodiment 4the strengthening spleen, tonifying kidney pill of control chronic renal failure, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Pyrolae 4 parts, Radix Aconiti Lateralis Preparata 5 parts, Rhizoma Dioscoreae 8 parts, Fructus Corni 7 parts, Semen Coicis 3.5 parts, Polyporus 2.5 parts, Radix Ginseng 9 parts, Herba Epimedii 4 parts, Scabrous Elephantfoot Herb 18 parts, 13 parts, Poria, Radix Cirsii Japonici 8 parts, 18 parts, Radix Rubiae, Semen Raphani 15 parts, Semen Cuscutae 12 parts, the Radix Astragali 17 parts, Pericarpium Citri Reticulatae 6.5 parts.
The strengthening spleen, tonifying kidney pill of above-mentioned control chronic renal failure, preparation process is as follows:
1. Pericarpium Citri Reticulatae and Polyporus are cleaned, be placed in shady and cool ventilation place and dry, after smashing to pieces, put into crock, add yellow wine, slightly stewing 2.5 hours, obtain wine Pericarpium Citri Reticulatae and Polyporus, wheat bran is placed in dry pot, by sliding for wheat bran parch sharp state, drop into wine Pericarpium Citri Reticulatae and Polyporus, repeatedly stir-fry 7 minutes, cease fire, sieve removes wheat bran, and the Pericarpium Citri Reticulatae good by parch and Polyporus are dried in the air and coolly grind to form smalls to cross 110 mesh sieves stand-by;
2. removed the peel by Rhizoma Dioscoreae, together clean, be cut into the block of beans size, be placed on food steamer, heat 18 minutes with Semen Raphani, within slightly stewing 10 minutes, take out, be laid on the upper little fire of clean iron plate and dry 9 minutes slowly, taking-up is dried in the air cool to room temperature, and it is stand-by to grind to form smalls;
3. Herba Pyrolae, Radix Aconiti Lateralis Preparata, Scabrous Elephantfoot Herb, Radix Ginseng and Radix Rubiae are cleaned, smash, dryouied by hot pot, drop into the crude drug handled well, repeatedly stir-fry 5 minutes, dry in the air to room temperature, it is stand-by to grind to form smalls;
4. by Fructus Corni, Semen Coicis, Herba Epimedii, Poria, Radix Cirsii Japonici, Semen Cuscutae and the Radix Astragali water soaking 65 minutes with 65 DEG C, be placed in marmite and decoct with water 40 minutes, water consumption is 3.5 times of crude drug gross weight, filters to get filtrate;
5. by step 1.-3. gained smalls and step 4. gained filtrate mix, fully stir after 9 minutes and add Mel, rapid stirring becomes thick paste, thick paste is dried 25 minutes, obtains drying object, and drying object is made circle according to the preparation for processing of pill, packs and get final product.
model case three:du XX, female, 55 years old, people from Jinan City, Shandong Province, for a long time dry farm work, in December, 2012 is examined, the intermittent soreness of the waist and knees of patient's readme unknown cause over 2 years, and dyspepsia, occasionally return the digestive symptoms such as acid, burn feeling, belch, ate the medicine of many treatment soreness of the waist and knees, effective at that time, but cure the symptoms, not the disease, can not effect a radical cure, become thin now obviously, weight loss.Doctor advised takes strengthening spleen, tonifying kidney pill of the present invention.
Take embodiment 4 gained strengthening spleen, tonifying kidney pill, every day three times, after breakfast, lunch and dinner, half an hour takes, and gets 3 at every turn, uses warm water delivery service.Take 15 days, the symptom such as dyspepsia, soreness of the waist and knees alleviates; Take 45 days, digestion is normal; Continue to take 2 months, malaise symptoms disappears completely, and body weight also recovers normal.
embodiment 5the strengthening spleen, tonifying kidney pill of control chronic renal failure, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Pyrolae 3 parts, Radix Aconiti Lateralis Preparata 4 parts, Rhizoma Dioscoreae 7 parts, Fructus Corni 6 parts, Semen Coicis 3 parts, Polyporus 2 parts, Radix Ginseng 8 parts, Herba Epimedii 3 parts, Scabrous Elephantfoot Herb 15 parts, 10 parts, Poria, Radix Cirsii Japonici 7 parts, 15 parts, Radix Rubiae, Semen Raphani 12 parts, Semen Cuscutae 10 parts, the Radix Astragali 14 parts, Pericarpium Citri Reticulatae 6 parts.
The strengthening spleen, tonifying kidney pill of above-mentioned control chronic renal failure, preparation process is as follows:
1. Pericarpium Citri Reticulatae and Polyporus are cleaned, be placed in shady and cool ventilation place and dry, after smashing to pieces, put into crock, add yellow wine, slightly stewing 2 hours, obtain wine Pericarpium Citri Reticulatae and Polyporus, wheat bran is placed in dry pot, by sliding for wheat bran parch sharp state, drop into wine Pericarpium Citri Reticulatae and Polyporus, repeatedly stir-fry 6 minutes, cease fire, sieve removes wheat bran, and the Pericarpium Citri Reticulatae good by parch and Polyporus are dried in the air and coolly grind to form smalls to cross 100 mesh sieves stand-by;
2. removed the peel by Rhizoma Dioscoreae, together clean, be cut into the block of beans size, be placed on food steamer, heat 15 minutes with Semen Raphani, within slightly stewing 10 minutes, take out, be laid on the upper little fire of clean iron plate and dry 8 minutes slowly, taking-up is dried in the air cool to room temperature, and it is stand-by to grind to form smalls;
3. Herba Pyrolae, Radix Aconiti Lateralis Preparata, Scabrous Elephantfoot Herb, Radix Ginseng and Radix Rubiae are cleaned, smash, dryouied by hot pot, drop into the crude drug handled well, repeatedly stir-fry 4 minutes, dry in the air to room temperature, it is stand-by to grind to form smalls;
4. by Fructus Corni, Semen Coicis, Herba Epimedii, Poria, Radix Cirsii Japonici, Semen Cuscutae and the Radix Astragali water soaking 60 minutes with 60 DEG C, be placed in marmite and decoct with water 35 minutes, water consumption is 3 times of crude drug gross weight, filters to get filtrate;
5. by step 1.-3. gained smalls and step 4. gained filtrate mix, fully stir after 8 minutes and add Mel, rapid stirring becomes thick paste, thick paste is dried 20 minutes, obtains drying object, and drying object is made circle according to the preparation for processing of pill, packs and get final product.
experimental example: in order to verify the effect of Chinese medicine strengthening spleen, tonifying kidney pill (embodiment 5) of the present invention, we have extracted 400 patients and have carried out the experiment of medicine, be equally divided into two groups, experimental group and matched group, experimental group takes gained strengthening spleen, tonifying kidney pill of the present invention, and matched group takes the medicine of other treatment control chronic renal failure.Inclusion criteria: have the one or more of chronic renal failure symptom.Curative effect situation criterion: 1, cure.After drug administration, malaise symptoms disappears completely; 2, effective.After drug administration, malaise symptoms alleviates or partial disappearance; 3, invalid.After drug administration, malaise symptoms is unchanged.
We have carried out accurate statistics and mathematical analysis to experimental data.Specific experiment result is as following table:
Strengthening spleen, tonifying kidney pill of the present invention cure rate compared with other medicine preventing and treating chronic renal failure is high, total effective rate is 99%, higher than matched group effective percentage by 29%, successful is better than matched group, this invention strengthening spleen, tonifying kidney pill is cheap, ordinary people life-time service, also can not increase health and pecuniary burden.Do not occur a routine side effect profile in clinical experiment, safety is far above the medicine of other control chronic renal failure, and instant effect, therapeutic process no pain prevents and treats chronic renal failure Chinese medicine the most fast and effectively at present.

Claims (10)

1. prevent and treat a strengthening spleen, tonifying kidney pill for chronic renal failure, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Pyrolae 1-5 part, Radix Aconiti Lateralis Preparata 2-6 part, Rhizoma Dioscoreae 4-10 part, Fructus Corni 3-8 part, Semen Coicis 2-4 part, Polyporus 1-3 part, Radix Ginseng 6-10 part, Herba Epimedii 1-5 part, Scabrous Elephantfoot Herb 10-20 part, Poria 5-15 part, Radix Cirsii Japonici 4-10 part, Radix Rubiae 10-20 part, Semen Raphani 7-18 part, Semen Cuscutae 6-14 part, Radix Astragali 8-19 part, Pericarpium Citri Reticulatae 5-7 part.
2. the strengthening spleen, tonifying kidney pill of control chronic renal failure according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Pyrolae 2-4 part, Radix Aconiti Lateralis Preparata 3-5 part, Rhizoma Dioscoreae 6-8 part, Fructus Corni 5-7 part, Semen Coicis 2.5-3.5 part, Polyporus 1.5-2.5 part, Radix Ginseng 7-9 part, Herba Epimedii 2-4 part, Scabrous Elephantfoot Herb 13-18 part, Poria 8-13 part, Radix Cirsii Japonici 6-8 part, Radix Rubiae 13-18 part, Semen Raphani 10-15 part, Semen Cuscutae 8-12 part, Radix Astragali 12-17 part, Pericarpium Citri Reticulatae 5.5-6.5 part.
3. the strengthening spleen, tonifying kidney pill of control chronic renal failure according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Pyrolae 3 parts, Radix Aconiti Lateralis Preparata 4 parts, Rhizoma Dioscoreae 7 parts, Fructus Corni 6 parts, Semen Coicis 3 parts, Polyporus 2 parts, Radix Ginseng 8 parts, Herba Epimedii 3 parts, Scabrous Elephantfoot Herb 15 parts, 10 parts, Poria, Radix Cirsii Japonici 7 parts, 15 parts, Radix Rubiae, Semen Raphani 12 parts, Semen Cuscutae 10 parts, the Radix Astragali 14 parts, Pericarpium Citri Reticulatae 6 parts.
4. the preparation method of the control chronic renal failure strengthening spleen, tonifying kidney pill according to any one of claim 1-3, is characterized in that: step is as follows:
1. Pericarpium Citri Reticulatae and Polyporus are cleaned, be placed in shady and cool ventilation place and dry, after smashing to pieces, put into crock, add yellow wine, slightly stewing 1-3 hour, obtains wine Pericarpium Citri Reticulatae and Polyporus, is placed in by wheat bran in dry pot, by sliding for wheat bran parch sharp state, drop into wine Pericarpium Citri Reticulatae and Polyporus, stir-fry 3-8 minute repeatedly, ceases fire, sieve removes wheat bran, and the Pericarpium Citri Reticulatae good by parch and Polyporus are dried in the air and coolly grind to form smalls to cross 80-120 mesh sieve stand-by;
2. removed the peel by Rhizoma Dioscoreae, together clean, be cut into the block of beans size, be placed on food steamer with Semen Raphani, heating 10-20 minute, within slightly stewing 10 minutes, take out, be laid on the upper little fire of clean iron plate and dry 5-10 minute slowly, take out and dry in the air cool to room temperature, it is stand-by to grind to form smalls;
3. Herba Pyrolae, Radix Aconiti Lateralis Preparata, Scabrous Elephantfoot Herb, Radix Ginseng and Radix Rubiae are cleaned, smash, dryouied by hot pot, drop into the crude drug handled well, stir-fry 2-6 minute repeatedly, dries in the air to room temperature, and it is stand-by to grind to form smalls;
4. by Fructus Corni, Semen Coicis, Herba Epimedii, Poria, Radix Cirsii Japonici, Semen Cuscutae and the Radix Astragali water soaking 50-70 minute with 50-70 DEG C, be placed in marmite and decoct with water 20-50 minute, water consumption is 2-4 times of crude drug gross weight, filters to get filtrate;
5. by step 1.-3. gained smalls and step 4. gained filtrate mix, fully stir after 5-10 minute and add Mel, rapid stirring becomes thick paste, thick paste is dried 10-30 minute, obtain drying object, drying object is made circle according to the preparation for processing of pill, packs and get final product.
5. the preparation method of strengthening spleen, tonifying kidney pill according to claim 4, is characterized in that: 1. step adds yellow wine, slightly stewing 1.5-2.5 hour (preferably adding yellow wine, slightly stewing 2 hours).
6. the preparation method of strengthening spleen, tonifying kidney pill according to claim 4, is characterized in that: 1. step drops into wine Pericarpium Citri Reticulatae and Polyporus, and stir-fry 5-7 minute (preferably drop into wine Pericarpium Citri Reticulatae and Polyporus, repeatedly stir-fry 6 minutes) repeatedly.
7. the preparation method of strengthening spleen, tonifying kidney pill according to claim 4, it is characterized in that: 2. step is placed on food steamer, heating 13-18 minute, slightly within stewing 10 minutes, take out, be laid on the upper little fire of clean iron plate to dry slowly and (be preferably placed on food steamer for 6-9 minute, heat 15 minutes, slightly within stewing 10 minutes, take out, be laid on the upper little fire of clean iron plate and dry 7 minutes slowly).
8. the preparation method of strengthening spleen, tonifying kidney pill according to claim 4, it is characterized in that: 3. step drops into the crude drug handled well, stir-fry 3-5 minute repeatedly, dries in the air to room temperature (preferably drop into the crude drug handled well, repeatedly stir-fry 4 minutes, dry in the air to room temperature).
9. the preparation method of strengthening spleen, tonifying kidney pill according to claim 4, it is characterized in that: step is 4. by the water soaking 55-65 minute of Fructus Corni, Semen Coicis, Herba Epimedii, Poria, Radix Cirsii Japonici, Semen Cuscutae and Radix Astragali 55-65 DEG C, be placed in marmite and decoct with water 30-40 minute, water consumption is that the 2.5-3.5 of crude drug gross weight is doubly (preferably by Fructus Corni, Semen Coicis, Herba Epimedii, Poria, Radix Cirsii Japonici, Semen Cuscutae and the Radix Astragali water soaking 60 minutes with 60 DEG C, be placed in marmite and decoct with water 35 minutes, water consumption is 3 times of crude drug gross weight).
10. the preparation method of strengthening spleen, tonifying kidney pill according to claim 4, it is characterized in that: 5. step fully stirs after 6-9 minute and add Mel, rapid stirring becomes thick paste, thick paste is dried and within 15-25 minute, (preferably fully stirs after 8 minutes and add Mel, rapid stirring becomes thick paste, thick paste is dried 20 minutes).
CN201510316511.9A 2015-06-11 2015-06-11 Spleen strengthening and kidney nourishing pill for preventing and curing chronic renal failure and preparation method thereof Pending CN104873841A (en)

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