CN103191362A - Traditional Chinese medicine granule for treating infantile diarrhea and preparation method of traditional Chinese medicine granule - Google Patents
Traditional Chinese medicine granule for treating infantile diarrhea and preparation method of traditional Chinese medicine granule Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine granule for treating infantile diarrhea. The traditional Chinese medicine granule is mainly composed of ginseng, poria cocos, bighead atractylodes rhizome, fried medicated leaven, roasted malt, scorched hawthorn fruit, Chinese yam, lotus nut, semen coicis, pericarpium citri reticulatae, fructus amomi, honey-fried licorice root, cane sugar and dextrin. By utilizing the traditional Chinese medicine granule, symptoms of collywobbles and oliguria caused by diarrhea can be effectively relieved. The traditional Chinese medicine granule for treating the infantile diarrhea has the effects of diminishing inflammation, sterilizing, repairing digestive tract mucous membrane and curing diarrhea, is safe and efficient, and does not have any side effects.
Description
Technical field
The invention discloses a kind of Chinese medicine granules, especially treat Chinese medicine granules of infantile diarrhea and preparation method thereof.The invention belongs to the Chinese medicine field.
Background technology
Diarrhoea is exactly " diarrhoea " that is commonly called as, and its symptom is that times of defecation, quantity increase, and excrement matter is thin or as water sample.Primary disease is more common in 2 years old with interior infant, and the age is littler, and sickness rate is higher.Bacterial infection and virus can cause diarrhoea, suffer from cold or improper diet also can cause and has loose bowels, and primary disease all can take place throughout the year, especially with summer and autumn for seeing more.The general prognosis bona of light disease that suffers from diarrhoea, serious symptom diarrhoea, serious symptom rickets, that underfed children's merges the then prognosis of suffering from diarrhoea is relatively poor, and certain case fatality rate is arranged.The diarrhoea traditional Chinese medical science is called and has loose bowels, and has comprised the alleged various antibacterials of doctor trained in Western medicine, virus and the enteritis and the dyspepsia that cause.
Infantile diarrhea shows as mainly that times of defecation increases and the character of defecating is thinning, normal companion's vomiting, heating, and severe patient can cause dehydration, electrolyte disturbance and acidosis.Light disease diarrhoea, general every day just time in 10 times, spirit still can, can take food, lack vomiting and nausea; Serious symptom person, surplus sudden attack of spouting diarrhea just time reaches 10 time or tens times, course of disease protracted course of disease, oliguria, even anuria, or extremity are not warm, and it is chilly to defecate.
The traditional Chinese medical science is according to the different causes of disease that cause infantile diarrhea, to have loose bowels and be divided into polytype: diarrhea due to improper diet refers to children's's belly distension pain, think stool during stomachache, diarrhoea back pain relief, stool acid is smelly or as the rotten egg abnormal smells from the patient, mixing with food residue or lump in breast, the eructating foul odor vomiting does not feel like a meal, even refusing to eat, vow that gas is smelly dirty, rolling is uneasy during nighttime sleep.Because rushed down by the cold and cool wind and cold that causes, it is rare clearly to see stool, and foam is many, and abnormal smells from the patient is not remarkable, and the stool color is yellowish, can hear that rumble, belly rumble rings, and with pain, the children's who has also has fever with aversion to cold concurrently, or nasal obstruction, limb aching pain.Damp and hot the rushing down often of having loose bowels due to the summer bacterial infection, the diarrhoea oncoming force is urgent, and it is thin defecate, and as water sample, color is deep yellow, and abnormal smells from the patient is smelly, or folder mucus, burning sensation of the anus, the stomachache battle array is cried, inappetence, or heating is tired noisy, thirst and liking drink, and yellow urine is few.Autumn and winter season, stool was often clear rare or half congealed thin shapeless when infecting virus, rushed down chilly or aqueous-grainy diarrhea down, and the stomachache happiness is warm, and hands and feet being not warm does not generate heat, and this is wind-cold syndrome; Part children's's body constitution is more weak, the course of disease of having loose bowels delay, the time when light heavy or the time end when sending out, it is thin defecate, color is light not smelly, accompanies indigestion breast food, desires after the food to rush down, polyphagia rushes down more, inappetence, shallow complexion, tired, emaciated physique, the splenoasthenic diarrhea of the genus traditional Chinese medical science.If incessant chronic diarrhea is eaten namely and rushed down, excrement matter is rare clearly, aqueous-grainy diarrhea, or see proctoptosis, and coldness of the body with chills, pale white complexion, listless, sleeping with eyes half-closed when sleeping is that deficiency of spleen-YANG and kidneyYANG rushes down.The children's that serious symptom is had loose bowels sees rushes down down immoderately, and matter is rare as water, oliguria, and xerosis cutis or withered flat, orbit and sunken fontanel, crying without tears, listless or fidgets due to deficiency is not peaceful, thirst and drinking, the dry tooth red lip is that impairment of YIN is rushed down.And chronic diarrhea or sudden attack of spouting diarrhea are more than, just rare as water, pale complexion or steel gray, a little less than the refreshing timid gas, apathetic expression, extreme cold of the limbs, skin is in a cold sweat, and then is that impairment of YANG is rushed down.
At present to the Therapeutic Principle of infantile diarrhea, with invigorating the spleen and regulating the stomach, dampness removing, help digestion, intestinal stasis relieving, infection be main.The medicine for the treatment of infantile diarrhea now clinically is more, Chinese patent medicine and Western medicine are arranged, but they are limited to the infantile diarrhea therapeutic effect, can not be at very short time internal therapy infantile diarrhea, make the deterioration that sustains damage of child's health, a kind of Chinese medicine composition for the treatment of diarrhoeal diseases (Granted publication number is: patent disclosure CN100358549C) a kind of Chinese medicine formula: it has Rhizoma Coptidis, the Radix Astragali, the Radix Paeoniae Alba, Herba Pogostemonis, Folium Psidii Guajavae, Poria is that raw material is made.It has the effect of heat-clearing and toxic substances removing, scorching antidiarrheal, but its course for the treatment of is long, generally needs three talentes to cure, and cure rate is also lower.
Summary of the invention
Present situation at existing treatment infantile diarrhea deficiency, one of purpose of the present invention is to provide a kind of Chinese medicine granules for the treatment of infantile diarrhea, have characteristics easy to operate, evident in efficacy, that have no side effect, and its adopts comparatively common in the localities Chinese crude drug as raw material, with low cost.
Another object of the present invention just provides the preparation method of above-mentioned treatment infantile diarrhea.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of Chinese medicine granules for the treatment of infantile diarrhea, preferred proportioning is taken off the primary raw material of stating weight proportion and is prepared from: Radix Ginseng 3-10 part, Poria 3-10 part, Rhizoma Atractylodis Macrocephalae 3-10 part, Massa Medicata Fermentata preparata 4-12 part, Fructus Hordei Germinatus (parched) 4-12 part, Fructus Crataegi (parched to brown) 4-12 part, RHIIZOMA DIOSCOREAE fr0m Henan of China 5-11 part, Semen Nelumbinis 3-10 part, Semen Coicis 3-10 part, Pericarpium Citri Reticulatae 2-9 part, Fructus Amomi 2-9 part, Radix Glycyrrhizae Preparata 2-9 part, sucrose 0.5-4 part, dextrin 0.5-4 part.
A kind of Chinese medicine granules for the treatment of infantile diarrhea, preferred proportioning is taken off the primary raw material of stating weight proportion and is prepared from: Radix Ginseng 4-9 part, Poria 4-9 part, Rhizoma Atractylodis Macrocephalae 4-9 part, Massa Medicata Fermentata preparata 5-10 part, Fructus Hordei Germinatus (parched) 5-10 part, Fructus Crataegi (parched to brown) 5-10 part, RHIIZOMA DIOSCOREAE fr0m Henan of China 6-10 part, Semen Nelumbinis 4-8 part, Semen Coicis 4-8 part, Pericarpium Citri Reticulatae 3-8 part, Fructus Amomi 3-8 part, Radix Glycyrrhizae Preparata 3-8 part, sucrose 1-3.5 part, dextrin 1-3.5 part.
A kind of Chinese medicine granules for the treatment of infantile diarrhea, more preferably proportioning is taken off the primary raw material of stating weight proportion and is prepared from: Radix Ginseng 5-7 part, Poria 5-7 part, Rhizoma Atractylodis Macrocephalae 5-7 part, Massa Medicata Fermentata preparata 6-9 part, Fructus Hordei Germinatus (parched) 6-9 part, Fructus Crataegi (parched to brown) 6-9 part, RHIIZOMA DIOSCOREAE fr0m Henan of China 6-9 part, Semen Nelumbinis 5-7 part, Semen Coicis 5-7 part, Pericarpium Citri Reticulatae 3-7 part, Fructus Amomi 3-7 part, Radix Glycyrrhizae Preparata 3-7 part, sucrose, 2-3 part, dextrin 2-3 part.
A kind of Chinese medicine granules for the treatment of infantile diarrhea, most preferred proportioning is taken off the primary raw material of stating weight proportion and is prepared from: 8 parts of Radix Ginsengs, 8 parts in Poria, 8 parts of the Rhizoma Atractylodis Macrocephalaes, 8 parts of Massa Medicata Fermentata preparatas, 8 parts of Fructus Hordei Germinatus (parched)s, 8 parts of Fructus Crataegi (parched to brown)s, 8 parts of RHIIZOMA DIOSCOREAE fr0m Henan of China, 7 parts in Semen Nelumbinis, 7 parts of Semen Coiciss, 6 parts of Pericarpium Citri Reticulataes, 6 parts of Fructus Amomis, 6 parts of Radix Glycyrrhizae Preparatas, 2.5 parts of sucrose, 2.5 parts in dextrin.
A kind of preparation method for the treatment of the infantile diarrhea Chinese medicine granules, preparation process is as follows:
1. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 1-3 hour, take out decocting liquid stand-by;
2. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 0.5-1.5 hour, take out decocting liquid stand-by;
3. 1. step is mixed with step decocting liquid 2., filter, it is 1.00-1.05(80 ℃ that filtrate is concentrated into relative density) (said 80 ℃ are the temperature of filtrate here), leave standstill, getting supernatant concentration to relative density is 1.30-1.35(80 ℃) clear paste;
4. add sucrose in the clear paste of obtaining, dextrin is made granule, drying.
1. the preparation method of above-mentioned Chinese medicine composition, step decoct 1-3 hour (preferred 2 hours).
2. the preparation method of above-mentioned Chinese medicine composition, step decoct 0.5-1.5 hour (preferred 1 hour).
The preparation method of above-mentioned Chinese medicine composition, step 3. filtrate to be concentrated into relative density be 1.00-1.05(80 ℃) (preferred 1.03), leave standstill, getting supernatant concentration to relative density is 1.30-1.35(80 ℃) (preferred 1.32).
Using method: reach optimum therapeuticing effect for making the present invention, the time spent gets and places cup in right amount, and boiled water is taken after mixing it with water, 2 times on the one.
This Chinese medicine granules has significant effect to the treatment infantile diarrhea, owing to be added with sucrose in the granule, can better allow child administration, easily absorb, series of advantages such as conscientiously, thus infantile diarrhea can effectively be treated, and multiselect of the present invention is with local common medical material, cheap, alleviated patient's financial burden.
A kind of Chinese medicine granules for the treatment of infantile diarrhea, the pharmacological effect of each crude drug is respectively:
Radix Ginseng: sweet little hardship, temperature.Strongly invigorating primordial QI is arranged, promote the production of body fluid admittedly take off, the effect of calming the nerves.It is deficient to control impairment caused by overstrain, lack of appetite, and asthenia, food is told in regurgitation, the stool lingering diarrhea, empty cough with asthma is short, the spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition is quenched one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion, and prolonged deficiency is not multiple, the card of all qi-blood-body fluid deficiencies.
Poria: sweet light, flat.Eliminating dampness and diuresis is arranged, strengthening the spleen stomach function regulating, the effect of mind tranquilizing and the heart calming.Control dysuria, the edema distension, the phlegm retention cough with dyspnea, the sound of vomiting of vomitting is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.
The Rhizoma Atractylodis Macrocephalae: bitter sweet, temperature.Spleen reinforcing is arranged, stomach reinforcing, dampness and in, antiabortive effect.Control deficient QI of the spleen and stomach, anorexia, the asthenia weak breath, deficiency-distension is had loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea uneasiness.
Massa Medicata Fermentata preparata: Gan Xin, temperature.Invigorating the spleen and regulating the stomach is arranged, the effect in the accent that helps digestion.Control retention of food and drink, feeling of stuffiness in chest abdominal distention, vomiting dysentery, postnatal blood stasis stomachache, children's's enlarged abdomen is hard long-pending.
Fructus Hordei Germinatus (parched): sweet, flat.Return spleen, stomach warp.Cure mainly food stagnation and do not disappear, abdominal distention, insufficiency of the spleen lack of appetite, newborn antiperspirant smoulders, distending pain of the breast, women's ablactation.
Fructus Crataegi (parched to brown): Fructus Crataegi (parched to brown): acid, sweet, tepor.Return Pi, stomach, Liver Channel, Fructus Crataegi has important medical value, since ancient times, just becomes the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, blood circulation promoting and blood stasis dispelling.
RHIIZOMA DIOSCOREAE fr0m Henan of China: belong to Rhizoma Dioscoreae, the spleen reinforcing nourishing the stomach is arranged, the lung benefiting that promotes the production of body fluid, the effect of the kidney invigorating arresting seminal emission.Be used for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.Be used for insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia.
Semen Nelumbinis: sweet puckery, flat.Nourish heart kidney tonifying, the effect of spleen reinforcing.Astringing intestine to stop diarrhea.Control the dreaminess of sleeping night, seminal emission, stranguria with turbid discharge, chronic dysentery, diarrhea of deficiency type, married woman's bleeding not during menses.Semen Caesalpiniae Minacis and energy preventing or arresting vomiting, appetizing, the fasting dysentery of controlling commonly used.
Stir-fried kidney beans: sweet in the mouth, warm in nature, nontoxic.Cure mainly tonic the five internal organs, preventing or arresting vomiting is told.Take for a long time, can make hair not white.Can separate the poison of all vegetations, give birth to chew to eat with liquor and drink, all effective.Make the pathogenic wind in the human body current, control woman's leukorrhagia, but alcoholic intoxication again, the poison of globe fish.Can cure dysentery, eliminate summer-heat, warm taste except remuval of damp and hot, are only quenched one's thirst.Grind into powder with vinegar and obey together down, it is more than to treat the cholera vomiting and diarrhoea.
Semen Coicis: sweet light, cold.Spleen invigorating is arranged, tonifying the lung, heat clearing away, the effect of dampness removing.Control and have loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea.
Pericarpium Citri Reticulatae: warm in nature, bitter in the mouth, suffering.Regulating qi-flowing for strengthening spleen is arranged, the effect of drying dampness to eliminate phlegm.Be used for fullness in the epigastrium and chest, lack of appetite and vomiting, cough ant phlegm.
Fructus Amomi: suffering, temperature.Stomach function regulating, the effect of being amusing are arranged in the circulation of qi promoting accent.Control the stomachache painful abdominal mass and expand anorexia dyspepsia, dysphagic vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant fetal movement.
Radix Glycyrrhizae Preparata: spleen reinforcing stomach function regulating, Yiqi and vein recovery.Be used for weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse can be separated the Radix Aconiti Lateralis Preparata poison.
Sucrose: the non-reducing disaccharide that is formed by the condensation of different body hydroxyl by glucose and fructose.Has sweet taste.Be excipient substance.
Dextrin: dextrin is a kind of powder of yellow-white, and it is insoluble to ethanol, and soluble in water, is dissolved in to have very strong viscosity in the water.Be excipient substance.
Chinese medicine granules of the present invention is based on the principle of traditional Chinese medical herbal treatment infantile diarrhea.The Chinese medicine medical material of selecting for use has the effect of antidiarrheal, and cheap, and life-time service also can not cause patient's financial burden, is the comparatively desirable medicine for the treatment of infantile diarrhea.
The specific embodiment
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1A kind of Chinese medicine granules for the treatment of infantile diarrhea takes off row raw material of Chinese medicine medicine: Radix Ginseng 3 grams, Poria 3 grams, the Rhizoma Atractylodis Macrocephalae 3 grams, Massa Medicata Fermentata preparata 4 grams, Fructus Hordei Germinatus (parched) 4 grams, Fructus Crataegi (parched to brown) 4 grams, RHIIZOMA DIOSCOREAE fr0m Henan of China 5 grams, Semen Nelumbinis 3 grams, Semen Coicis 3 grams, 2 parts of Pericarpium Citri Reticulataes, Fructus Amomi 2 grams, Radix Glycyrrhizae Preparata 2 grams, sucrose 0.5 gram, dextrin 0.5 gram.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 1 hour, take out decocting liquid stand-by;
2. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 0.5 hour, take out decocting liquid stand-by;
3. 1. step is mixed with step decocting liquid 2., filter, it is 1.00(80 ℃ that filtrate is concentrated into relative density), leave standstill, getting supernatant concentration to relative density is 1.30(80 ℃) clear paste;
4. add sucrose in the clear paste of obtaining, dextrin is made granule, drying.
Model case oneLiu XX, woman, 3 years old, Guangrao County, Shandong Province's Dongying city.Symptom: vomiting, diarrhoea was examined over 1 day, and vomitus is gastric content, and stool is 4-5 time on the 1st, becomes the egg style just, takes Chinese medicine composition of the present invention, just cures in 1 day.
Embodiment 2A kind of Chinese medicine granules for the treatment of infantile diarrhea takes off row raw material of Chinese medicine medicine: Radix Ginseng 10 grams, Poria 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Massa Medicata Fermentata preparata 12 grams, Fructus Hordei Germinatus (parched) 12 grams, Fructus Crataegi (parched to brown) 12 grams, RHIIZOMA DIOSCOREAE fr0m Henan of China 11 grams, Semen Nelumbinis 10 grams, Semen Coicis 10 grams, Pericarpium Citri Reticulatae 9 grams, Fructus Amomi 9 grams, Radix Glycyrrhizae Preparata 9 grams, sucrose 4 grams, dextrin 4 grams.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 1.5 hours, take out decocting liquid stand-by;
2. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 1 hour, take out decocting liquid stand-by;
3. 1. step is mixed with step decocting liquid 2., filter, it is 1.01(80 ℃ that filtrate is concentrated into relative density), leave standstill, getting supernatant concentration to relative density is 1.31(80 ℃) clear paste;
4. add sucrose in the clear paste of obtaining, dextrin is made granule, drying.
Model case 2:King XX, the women, 10 months are big.Suffered from diarrhoea 7 days, it is green that stool is, and defecates 5-6 time on the one, and transfusion is had an injection, and intestinal lavage is all invalid.Taking this Chinese medicine fully recovers one day after.
Embodiment 3A kind of Chinese medicine granules for the treatment of infantile diarrhea takes off row raw material of Chinese medicine medicine: Radix Ginseng 5 grams, Poria 5 grams, the Rhizoma Atractylodis Macrocephalae 5 grams, Massa Medicata Fermentata preparata 6 grams, Fructus Hordei Germinatus (parched) 6 grams, Fructus Crataegi (parched to brown) 6 grams, RHIIZOMA DIOSCOREAE fr0m Henan of China 6 grams, Semen Nelumbinis 5 grams, Semen Coicis 5 grams, Pericarpium Citri Reticulatae 3 grams, Fructus Amomi 3 grams, Radix Glycyrrhizae Preparata 3 grams, sucrose 2 grams, dextrin 2 grams.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 2 hours, take out decocting liquid stand-by;
2. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 1.5 hours, take out decocting liquid stand-by;
3. 1. step is mixed with step decocting liquid 2., filter, it is 1.02(80 ℃ that filtrate is concentrated into relative density), leave standstill, getting supernatant concentration to relative density is 1.32(80 ℃) clear paste;
4. add sucrose in the clear paste of obtaining, dextrin is made granule, drying.
Model case 3:The male, king xx, 15 months are big.Autumn morbidity suffer from diarrhoea one month, and it is all invalid that transfusion is had an injection, diarrhoea every day 7-8 time, and the diarrhoea amount is many at every turn, and defecating is yellow, rare watery stool, the urine amount is few, with vomiting.Take this medicine four times, six hours clothes were once fully recovered in one day.
Embodiment 4A kind of Chinese medicine granules for the treatment of infantile diarrhea takes off row raw material of Chinese medicine medicine: Radix Ginseng 7 grams, Poria 7 grams, the Rhizoma Atractylodis Macrocephalae 7 grams, Massa Medicata Fermentata preparata 9 grams, Fructus Hordei Germinatus (parched) 9 grams, Fructus Crataegi (parched to brown) 9 grams, RHIIZOMA DIOSCOREAE fr0m Henan of China 9 grams, Semen Nelumbinis 7 grams, Semen Coicis 7 grams, Pericarpium Citri Reticulatae 7 grams, Fructus Amomi 7 grams, Radix Glycyrrhizae Preparata 7 grams, sucrose 3 grams, dextrin 3 grams.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 2.5 hours, take out decocting liquid stand-by;
2. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 2 hours, take out decocting liquid stand-by;
3. 1. step is mixed with step decocting liquid 2., filter, it is 1.03(80 ℃ that filtrate is concentrated into relative density), leave standstill, getting supernatant concentration to relative density is 1.33(80 ℃) clear paste;
4. add sucrose in the clear paste of obtaining, dextrin is made granule, drying.
Model case 4: Lu XX,The male, six months big, suffered from diarrhoea body temperature 38 degree, oliguria 3 days.Stool is green, and it is inferior surplus one day 10 defecate, takes medicine and cures in one day.
Embodiment 5A kind of Chinese medicine granules for the treatment of infantile diarrhea takes off row raw material of Chinese medicine medicine: 8 parts of Radix Ginsengs, 8 parts in Poria, 8 parts of the Rhizoma Atractylodis Macrocephalaes, 8 parts of Massa Medicata Fermentata preparatas, 8 parts of Fructus Hordei Germinatus (parched)s, 8 parts of Fructus Crataegi (parched to brown)s, 8 parts of RHIIZOMA DIOSCOREAE fr0m Henan of China, 7 parts in Semen Nelumbinis, 7 parts of Semen Coiciss, 6 parts of Pericarpium Citri Reticulataes, 6 parts of Fructus Amomis, 6 parts of Radix Glycyrrhizae Preparatas, 2.5 parts of sucrose, 2.5 parts of compositions of dextrin.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 3 hours, take out decocting liquid stand-by;
2. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 2.5 hours, take out decocting liquid stand-by;
3. 1. step is mixed with step decocting liquid 2., filter, it is 1.04(80 ℃ that filtrate is concentrated into relative density), leave standstill, getting supernatant concentration to relative density is 1.34(80 ℃) clear paste;
4. add sucrose in the clear paste of obtaining, dextrin is made granule, drying.
Experimental example
In July 1 year May in 2011, have 300 patients and use inclusion criteria: be diagnosed as infantile diarrhea, and one of infantile diarrhea or several symptoms are arranged.Be divided into three groups at random, two groups of one group of experimental group and matched groups, experimental group uses embodiment 5 gained Chinese medicine granules, two groups of matched groups, one group is used the Western medicine diarrhea, and one group is used the Chinese medicine diarrhea, using method is: get and place cup in right amount, boiled water is taken after mixing it with water, 2 times on the one.
Curative effect situation criterion: 1, cure, use with 1 week of this product the malaise symptoms complete obiteration; 2, effective, use 1 week of this product, malaise symptoms alleviates or part disappears; 3, invalid, use 1 week of this product, the malaise symptoms no change.We have carried out statistics and mathematical analysis to data.Concrete experimental result such as following table:
Table 1: take medication effect
Prove through clinical trial, Chinese medicine granules of the present invention is on the treatment infantile diarrhea, cure rate is 98%, Western medicine diarrhea cure rate is high by 88% than taking, higher by 58% than Chinese medicine diarrhea cure rate, Chinese medicine granules of the present invention is based on the theory of Chinese medicine infantile diarrhea, see through the direct administration in acupuncture point and affected part, injection speed is fast, can fast and effeciently alleviate the symptom of stomach-ache, Most patients has effectively alleviated patient's misery using the present invention can fully recover in 3 days, and the present invention is a kind of Chinese medicine granules for the treatment of infantile diarrhea safely and effectively.
Claims (8)
1. a Chinese medicine granules for the treatment of infantile diarrhea is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Radix Ginseng 3-10 part, Poria 3-10 part, Rhizoma Atractylodis Macrocephalae 3-10 part, Massa Medicata Fermentata preparata 4-12 part, Fructus Hordei Germinatus (parched) 4-12 part, Fructus Crataegi (parched to brown) 4-12 part, RHIIZOMA DIOSCOREAE fr0m Henan of China 5-11 part, Semen Nelumbinis 3-10 part, Semen Coicis 3-10 part, Pericarpium Citri Reticulatae 2-9 part, Fructus Amomi 2-9 part, Radix Glycyrrhizae Preparata 2-9 part, sucrose 0.5-4 part, dextrin 0.5-4 part.
2. according to the described Chinese medicine granules of claim 1, it is characterized in that, take off the primary raw material of stating weight proportion and be prepared from: Radix Ginseng 4-9 part, Poria 4-9 part, Rhizoma Atractylodis Macrocephalae 4-9 part, Massa Medicata Fermentata preparata 5-10 part, Fructus Hordei Germinatus (parched) 5-10 part, Fructus Crataegi (parched to brown) 5-10 part, RHIIZOMA DIOSCOREAE fr0m Henan of China 6-10 part, Semen Nelumbinis 4-8 part, Semen Coicis 4-8 part, Pericarpium Citri Reticulatae 3-8 part, Fructus Amomi 3-8 part, Radix Glycyrrhizae Preparata 3-8 part, sucrose 1-3.5 part, dextrin 1-3.5 part.
3. according to the described Chinese medicine granules of claim 1, it is characterized in that, take off the primary raw material of stating weight proportion and be prepared from: Radix Ginseng 5-7 part, Poria 5-7 part, Rhizoma Atractylodis Macrocephalae 5-7 part, Massa Medicata Fermentata preparata 6-9 part, Fructus Hordei Germinatus (parched) 6-9 part, Fructus Crataegi (parched to brown) 6-9 part, RHIIZOMA DIOSCOREAE fr0m Henan of China 6-9 part, Semen Nelumbinis 5-7 part, Semen Coicis 5-7 part, Pericarpium Citri Reticulatae 3-7 part, Fructus Amomi 3-7 part, Radix Glycyrrhizae Preparata 3-7 part, sucrose, 2-3 part, dextrin 2-3 part.
4. a Chinese medicine granules for the treatment of infantile diarrhea is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: 8 parts of Radix Ginsengs, 8 parts in Poria, 8 parts of the Rhizoma Atractylodis Macrocephalaes, 8 parts of Massa Medicata Fermentata preparatas, 8 parts of Fructus Hordei Germinatus (parched)s, 8 parts of Fructus Crataegi (parched to brown)s, 8 parts of RHIIZOMA DIOSCOREAE fr0m Henan of China, 7 parts in Semen Nelumbinis, 7 parts of Semen Coiciss, 6 parts of Pericarpium Citri Reticulataes, 6 parts of Fructus Amomis, 6 parts of Radix Glycyrrhizae Preparatas, 2.5 parts of sucrose, 2.5 parts in dextrin.
5. according to the preparation method of the arbitrary Chinese medicine granules of claim 1-3, it is characterized in that preparation process is as follows:
1. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 1-3 hour, take out decocting liquid stand-by;
2. with Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae, Massa Medicata Fermentata preparata, Fructus Hordei Germinatus (parched), Fructus Crataegi (parched to brown), RHIIZOMA DIOSCOREAE fr0m Henan of China, Semen Nelumbinis, Semen Coicis, Pericarpium Citri Reticulatae, Fructus Amomi, Radix Glycyrrhizae Preparata decoct with water 0.5-1.5 hour, take out decocting liquid stand-by;
3. 1. step is mixed with step decocting liquid 2., filter, it is 1.00-1.05(80 ℃ that filtrate is concentrated into relative density), leave standstill, getting supernatant concentration to relative density is 1.30-1.35(80 ℃) clear paste;
4. add sucrose in the clear paste of obtaining, dextrin is made granule, drying.
6. according to the described preparation method of claim 4, it is characterized in that 1. step decocts 1-3 hour (preferred 2 hours).
7. preparation method according to claim 4 is characterized in that, 2. step decocts 0.5-1.5 hour (preferred 1 hour).
8. preparation method according to claim 4 is characterized in that, step 3. filtrate to be concentrated into relative density be 1.00-1.05(80 ℃) (preferred 1.03), leave standstill, getting supernatant concentration to relative density is 1.30-1.35(80 ℃) (preferred 1.32).
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