CN107998366A - It is a kind of suitable for Chinese medicine composition of puerpera's lactagogue at initial stage in postpartum and preparation method thereof - Google Patents
It is a kind of suitable for Chinese medicine composition of puerpera's lactagogue at initial stage in postpartum and preparation method thereof Download PDFInfo
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- CN107998366A CN107998366A CN201810118946.6A CN201810118946A CN107998366A CN 107998366 A CN107998366 A CN 107998366A CN 201810118946 A CN201810118946 A CN 201810118946A CN 107998366 A CN107998366 A CN 107998366A
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Abstract
The invention discloses a kind of suitable for Chinese medicine composition of puerpera's lactagogue at initial stage in postpartum and preparation method thereof, including following material medicine：5 15g of Ligusticum wallichii, 5 15g of profound Hu, 5 15g of the stem pith of the rice-paper plant, 5 15g of safflower, 5 15g of dried orange peel, 5 15g of radix glycyrrhizae, 5 15g of rhizoma cyperi, 10 15g of motherwort, 5 15g of fennel seeds, 20 30g of hawthorn, 20 25g of Radix Rhapontici seu Radix Echinopsis, 5 8g of Angelica sinensis, 20 40g of pangolin, 5 15g of rhizoma zingiberis, 5 15g of peach kernel, 20 30g of the radix paeoniae rubrathe, 20 30g of the seed of cowherb.The Chinese medicine composition of the present invention is according to the own metabolism and circulation law of initial stage in postpartum (in 15 days postpartum) puerpera, filthy in vivo to discharge, dredging the channel, supplements qi and blood, promoting lactation is stimulated the secretion of milk, the Chinese medicine has effects that promoting blood circulation and removing blood stasis, while the effect of have benefiting qi and nourishing blood concurrently, lactagogue effect is more notable, the proliferation of mammary gland can also be treated, to promoting breast-feeding to be of great significance, and the present invention can improve the resistance of puerpera and baby, have higher nutritive value.
Description
Technical field
The present invention relates to a kind of suitable for Chinese medicine composition of puerpera's lactagogue at initial stage in postpartum and preparation method thereof, belong to Chinese medicine
Field.
Background technology
Breast milk is the juice for being used as nurture baby that postpartum female breast produces, and contains lactoferrin, carbon aquation in breast milk
Compound, protein, fat, vitamin, mineral matter, aliphatic acid and taurine etc., are that neonate is born most important nutrition at initial stage
Material source.Breast-feeding is all beneficial for newborn woman and natus, and breast milk is full of nutrition, is easy to digest, and pollutes less simultaneously
Containing a variety of antibacteriums and antiviral antibody, baby's illness rate and the death rate can be reduced, is conducive to the recovery of pregnant woman postpartum uterus.
However, breast milk is obstructed or hypogalactia, agalasisa become puerpera's common disease.Puerpera in lactation milk very less or completely without being insufficient to even
The person that is unable to feeding infant, is known as hypogalactia after delivery.Hypogalactia after delivery not only influences the normal lactation of puerpera, and the health for influencing baby is raw
It is long, while also psychological pressure is brought to puerpera and household.Postpartum milk rareness ancients have discussion more, such as《Married woman's good recipe》
Claim, married woman's milk is qi and blood, and sub- milk is given birth to if vigour weakness and is lacked.It is bright《Production mirror》Referred to as alactation, Zhang Jingyue pair
Chronic diseases marked by deficiency of vital energy hypogalactia proposes " benefitization source and claim tonneau ".At present, it is many that method and the medicine of hypogalactia of lying-in woman disease are treated, it is among the people just to have much
Dietotherapy or the special prescription of Chinese herbal medicine of hypogalactia are treated, has the effect of certain to treatment hypogalactia of lying-in woman, but can seldom reach satisfied effect, is imitated
Fruit is slow, cure rate is low, has delayed the best opportunity of lactagogue.The period of lactagogue best results is in 3-15 days postpartum, therefore research and development
The Chinese medicine of galactopoiesis is promoted to be of great significance in a kind of 15 days postpartum.
The content of the invention
The technical problems to be solved by the invention are to provide a kind of Chinese medicine composition suitable for puerpera's lactagogue at initial stage in postpartum
And preparation method thereof, it can effectively ensure that the lactagogue effect of puerpera at initial stage in postpartum.
To achieve these goals, the technical solution adopted in the present invention is：
A kind of Chinese medicine composition suitable for puerpera's lactagogue at initial stage in postpartum, including following material medicine：It is Ligusticum wallichii 5-15g, profound
Hu 5-15g, stem pith of the rice-paper plant 5-15g, safflower 5-15g, dried orange peel 5-15g, radix glycyrrhizae 5-15g, rhizoma cyperi 5-15g, motherwort 10-15g, fennel seeds
5-15g, hawthorn 20-30g, Radix Rhapontici seu Radix Echinopsis 20-25g, Angelica sinensis 5-8g, pangolin 20-40g, rhizoma zingiberis 5-15g, peach kernel 5-15g, radix paeoniae rubrathe 20-
30g, seed of cowherb 20-30g.
A kind of preparation method of Chinese medicine composition, comprises the following steps：
(1) each material medicine is weighed by weight, is mixed, and the water for adding 10-15 times of mixed material drug weight decocts 2-3
Secondary, each 1-1.5h, merges decocting liquid, freezes, and Chinese medicine freeze-dried powder is made；
(2) biofermentation is used, Chinese medicine freeze-dried powder is seeded in the mixed bacteria liquid of 10-20 times of weight, sealed fermenting 30-
50h, the mixed bacteria liquid include：Bacillus subtilis 2 × 108Cfu/mL, Lactobacillus casei 3 × 108Cfu/mL, plant breast
Bacillus 2 × 108Cfu/mL, bifidobacterium breve 1 × 108Cfu/mL, saccharomycete 1 × 108cfu/mL；
(3) by zymotic fluid after filtering, it is canned to obtain the final product.
A kind of preparation method of Chinese medicine composition, weighs each material medicine by weight, and mixing, adds mixed material medicine weight
The water of 10-15 times of amount decocts 2-3 times, each 1-1.5h, merges decocting liquid.
A kind of preparation method of Chinese medicine composition, comprises the following steps：
(1) Ligusticum wallichii, profound Hu, the stem pith of the rice-paper plant, safflower, dried orange peel are weighed by weight, is mixed, and add 5-15 times of mixed material drug weight
Volumetric concentration 90% ethanol, refluxing extraction 2-3 times under the conditions of 70-80 DEG C, each 1-1.5h, filtering, merging filtrate warp
Ethanol is recovered under reduced pressure to no alcohol taste, and is condensed into the extractum A that relative density at 60 DEG C is 1.10-1.12；
(2) radix glycyrrhizae, rhizoma cyperi, motherwort, fennel seeds, hawthorn, Radix Rhapontici seu Radix Echinopsis, Angelica sinensis, rhizoma zingiberis, peach kernel, the radix paeoniae rubrathe, king are weighed by weight
Row is not stayed, is mixed, the water for adding 10-15 times of mixed material drug weight decocts 2-3 times, each 1-1.5h, filtering, merging filtrate
And it is condensed into the medicinal extract B that relative density at 80 DEG C is 1.20-1.30；
(3) 100 mesh sieves are crossed after pangolin is crushed, it is spare；
(4) extractum A, medicinal extract B are uniformly mixed, concentrate, be dried to dry extract, crushed, and the mixing of pangolin powder, Ran Houjia
Enter auxiliary material, remix uniformly, pelletize, it is dry, to obtain the final product.
Auxiliary material is starch, dextrin or white sugar, and dosage is the 20-30% of material medicine gross weight.
The pharmacology of each component of the present invention is as follows：
Ligusticum wallichii, acrid flavour are warm-natured.Return liver, gallbladder channel.Promote breath and open depression, method wind-dryness is wet, promoting blood circulation and stopping pain.It is dizzy to cure mainly air-cooled headache rotation,
Hypochondriac pain abdomen aches, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores.For irregular menstruation, closed dysmenorrhea, lump in the abdomen abdomen
Bitterly, chest side of body shouting pain, tumbling and swelling, headache, arthralgia pain due to rheumatism.
Profound Hu, acrid flavour is bitter, warm-natured.Return liver warp, stomach, the heart, warp, the spleen channel.Promoting blood circulation, dissipates the stasis of blood, qi-regulating, analgesic.Cure mainly trusted subordinate's waist
The all pains of knee, irregular menstruation, abdominal mass, metrorrhagia, postpartum anemic fainting, lochiorrhagia, traumatic injury.
The stem pith of the rice-paper plant, sweet in flavor, cold nature.Attach to the lung and stomach meridians.Clear wet Li Shui；Promoting lactation.Cure mainly the puckery pain of stranguria, difficult urination, oedema,
Jaundice, damp-warm diseases, scanty drak urine, postpartum breast is few, Amenorrhea, under band.For damp-warm syndrome urine, the puckery pain of gonorrhoea, oedema oliguria, milk is not
Under.
Safflower, acrid flavour are warm-natured.Converge to heart and liver channels.Invigorate blood circulation, stasis eliminatings analgesic.Cure mainly Amenorrhea, abdominal mass, difficult labour, stillborn foetus, production
Lochia, hemostasis are had a pain afterwards, carbuncle swells, injury from falling down.
Dried orange peel, it is bitter, pungent, it is warm-natured.Return lung, the spleen channel.Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.Abdominal fullness and distention is cured mainly, deficiency of food is vomited and diarrhoea,
Coughing with a lot of sputum.
Radix glycyrrhizae, it is sweet in flavor, it is mild-natured.The thoughts of returning home, spleen, lung, stomach.Invigorate the spleen and benefit qi, moisten the lung and relieve the cough, it is clearing heat and detoxicating, alleviate analgesic, delay
And pharmacological property.
Rhizoma cyperi, acrid flavour, slight bitter, micro-sweet are mild-natured.Return liver, spleen, tri-jiao channel.Regulating the flow of vital energy Xie Yu, relieves pain menstruation regulating.Cure mainly liver stomach not
With, depression of QI, phlegm and retained fluid feeling of fullness, under uterine bleeding band, stagnation of QI due to depression of the liver, chest, the side of body, abdominal distention, indigestion, chest gastral cavity ruffian, cold hernia
Abdominal pain, swollen breasts, irregular menstruation, closed dysmenorrhea.《Detailed outline》Carry：" gas is trembled with fear epidemic disease when dissipating, and profit three is burnt, Xie Liuyu, the diet that disappears product
Poly-, phlegm and retained fluid feeling of fullness, instep swells, abdominal distension, tinea pedis, only trusted subordinate, limbs, head, mesh, tooth, all pains of ear, and ulcer sores, spit blood, lower blood, urine
Blood, under married woman's uterine bleeding band, the moon waits uncomfortable, postpartum all kinds of diseases and ailments before tire.”
Motherwort, it is bitter, pungent, it is cold in nature.The thoughts of returning home, liver, bladder warp.It is promoting blood circulation and removing blood stasis, inducing diuresis for removing edema.Irregular menstruation is cured mainly, is produced
Stasis blocking afterwards, traumatic injury, oedema, difficult urination, sore and toxic, itchy skin eruption.
Fennel seeds, acrid flavour are warm-natured.Return kidney channel.Stomach invigorating, promoting the circulation of qi, analgesic.Cure mainly stomach cold pain, cold and pain in the lower abdomen, dysmenorrhoea, colic,
Hydrocele testis, snail fever.
Hawthorn, sour sweet, slightly warm in nature.Returns spleen, stomach, Liver Channel.Digestion gathered food, scattered blood stasis, expelling tenia.Control meat product, abdominal mass, phlegm
Drink, feeling of fullness, acid regurgitation, rush down dysentery, intestines wind, pain in the back, hernia postpartum postpartum abdominal pain, lochiorrhagia, pediatric milk food stagnation.Food digesting stomach fortifying, OK
Gas dissipates the stasis of blood.For meat stagnation, gastric ulcer fullness, diarrhea dysentery abdominal pain, blood stasis closed, postpartum stasis, confidant sting, hernia pain, height
Blood fat disease.
Radix Rhapontici seu Radix Echinopsis, bitter are cold in nature.Return stomach.Clearing heat and detoxicating, disappear carbuncle, and lower breast, relaxing muscles and tendons is promoted blood circulation.Cure mainly acute mastitis swelling and pain, ulcer hair
The back of the body, scrofula sore, alactation, arthritis with fixed pain caused by dampness contraction.
Angelica sinensis, it is sweet in flavor, pungent, it is warm-natured.Return liver, the heart, the spleen channel.Enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation.The main deficiency of blood is all
Card, irregular menstruation, Amenorrhea, dysmenorrhoea, abdominal mass knot gather, and uterine bleeding, asthenia cold abdominalgia, Impotence numbness, numbness, intestines are dry and shit is difficult, weight after dysentery characterized by blood in the stool,
Ulcer sores, injury from falling down.
Pangolin, taste is salty, cold nature；Return liver, stomach.Blood circulation promoting and dispersing pathogen accumulation, newborn under promoting menstruation, anti-stain in solid.Cure mainly blood stasis,
Abdominal mass, arthralgia pain due to rheumatism, agalactia, carbuncle swells, scrofula.《Detailed outline》Carry：" eliminating phlegm malaria fever and chills, the tetanic pain of wandering arthritis, qualcomm meridian, under
Milk, subduing inflammation, apocenosis blood, sensible desinsection ".
Rhizoma zingiberis, acrid flavour, property heat.Returns spleen, stomach, kidney, the heart, lung channel.Warming spleen and stomach for dispelling cold, Back to Yang Tongmai, Wenfei of drink.Cure mainly gastral cavity abdomen
Crymodynia, vomiting and diarrhea, cold weak pulse of limb, cold drink are breathed with cough.
Peach kernel, it is bitter, sweet, it is mild-natured.The thoughts of returning home, liver, large intestine channel.Promoting blood circulation, relaxes bowel, relieving cough and asthma.Cure mainly Amenorrhea
Dysmenorrhoea, lump in the abdomen lump in the abdomen lump in the abdomen, lung carbuncle acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma.
The radix paeoniae rubrathe, bitter, cold nature.Return liver warp.Clearing heat and cooling blood, removing blood stasis and analgesics.For thermal man's ying blood, febrile virulent maculae, spits blood
Bleeding from five sense organs or subcutaneous tissue, red eye, swell pain, liver-depressed hypochondrium pain, closed dysmenorrhea, addiction lump in the abdomen abdominal pain, injury from falling down, carbuncle swells sore.
The seed of cowherb, bitter are mild-natured.Return liver, stomach.Invigorate blood circulation, lower breast detumescence, inducing diuresis for treating strangurtia.Amenorrhea is cured mainly, pain
Through, agalactia, acute mastitis swelling and pain, the puckery pain of stranguria.
Beneficial effects of the present invention：
The Chinese medicine composition of the present invention according to the own metabolism and circulation law of initial stage in postpartum (in 15 days postpartum) puerpera, with
Discharge is filthy in vivo, dredging the channel, supplements qi and blood, and promoting lactation is stimulated the secretion of milk, which has effects that promoting blood circulation and removing blood stasis, while has tonifying Qi concurrently
The effect of blood-nourishing, lactagogue effect are more notable, additionally it is possible to the proliferation of mammary gland is treated, to promoting breast-feeding to be of great significance, and
The present invention can improve the resistance of puerpera and baby, have higher nutritive value.
The present invention is prepared using pure natural Chinese herbal medicine raw material, and Radix Rhapontici seu Radix Echinopsis, the seed of cowherb are monarch drug in a prescription in prescription, and safflower, Angelica sinensis, lead to
Grass, Ligusticum wallichii, pangolin are ministerial drug, respectively promoting blood circulation and removing blood stasis into after subassembly, focusing on, and have benefiting qi and nourishing blood concurrently.Compatibility is reasonable between component, association
Same synergy, curative effect is good, and cost is low, is the Innovative TCMs of postpartum lactagogue.
The present invention uses biotechnology fermentation in technique, can improve mouthfeel, curative effect speed-raising, attenuation synergistic.
Formulation of the present invention can make the formulations such as decoction, granule or pill according to the market demand, convenient to take.
Chinese medicine of the present invention is without any side effects, and curative effect is obvious, and cure rate is higher, statistics show total effective rate 95% with
On.In general symptom 3 days effectively, it even served healing in 3-6 days.
Embodiment
The embodiment of the present invention is described in further detail with reference to embodiments.
Embodiment 1
A kind of Chinese medicine composition suitable for puerpera's lactagogue at initial stage in postpartum, including following material medicine：Ligusticum wallichii 5g, profound Hu
5g, stem pith of the rice-paper plant 5g, safflower 5g, dried orange peel 5g, radix glycyrrhizae 5g, rhizoma cyperi 5g, motherwort 10g, fennel seeds 5g, hawthorn 20g, Radix Rhapontici seu Radix Echinopsis 20g, Angelica sinensis
5g, pangolin 20g, rhizoma zingiberis 5g, peach kernel 5g, radix paeoniae rubrathe 20g, seed of cowherb 20g.
Preparation method, comprises the following steps：
(1) each material medicine is weighed by weight, is mixed, the water decoction of 10 times of addition mixed material drug weight 3 times, every time
1.5h, merges decocting liquid, freezes, and Chinese medicine freeze-dried powder is made；
(2) biofermentation is used, Chinese medicine freeze-dried powder is seeded in the mixed bacteria liquid of 15 times of weight, sealed fermenting 40h, institute
Stating mixed bacteria liquid includes：Bacillus subtilis 2 × 108Cfu/mL, Lactobacillus casei 3 × 108Cfu/mL, lactobacillus plantarum 2 ×
108Cfu/mL, bifidobacterium breve 1 × 108Cfu/mL, saccharomycete 1 × 108cfu/mL；
(3) by zymotic fluid after filtering, it is canned to obtain the final product.
Embodiment 2
A kind of Chinese medicine composition suitable for puerpera's lactagogue at initial stage in postpartum, including following material medicine：Ligusticum wallichii 10g, profound Hu
10g, stem pith of the rice-paper plant 10g, safflower 10g, dried orange peel 10g, radix glycyrrhizae 10g, rhizoma cyperi 10g, motherwort 12g, fennel seeds 10g, hawthorn 25g, Radix Rhapontici seu Radix Echinopsis
22g, Angelica sinensis 6g, pangolin 30g, rhizoma zingiberis 10g, peach kernel 10g, radix paeoniae rubrathe 25g, seed of cowherb 25g.
Preparation method, comprises the following steps：Each material medicine is weighed by weight, is mixed, and adds mixed material drug weight
15 times of water decocts 2 times, each 1h, merges decocting liquid.
Embodiment 3
A kind of Chinese medicine composition suitable for puerpera's lactagogue at initial stage in postpartum, including following material medicine：Ligusticum wallichii 15g, profound Hu
15g, stem pith of the rice-paper plant 15g, safflower 15g, dried orange peel 15g, radix glycyrrhizae 15g, rhizoma cyperi 15g, motherwort 15g, fennel seeds 15g, hawthorn 30g, Radix Rhapontici seu Radix Echinopsis
25g, Angelica sinensis 8g, pangolin 40g, rhizoma zingiberis 15g, peach kernel 15g, radix paeoniae rubrathe 30g, seed of cowherb 30g.
Preparation method, comprises the following steps：
(1) Ligusticum wallichii, profound Hu, the stem pith of the rice-paper plant, safflower, dried orange peel are weighed by weight, is mixed, and add 5 times of mixed material drug weight
The ethanol of volumetric concentration 90%, refluxing extraction 3 times under the conditions of 70 DEG C, each 1h, filtering, merging filtrate is through being recovered under reduced pressure ethanol
To no alcohol taste, and it is condensed into the extractum A that relative density at 60 DEG C is 1.10-1.12；
(2) radix glycyrrhizae, rhizoma cyperi, motherwort, fennel seeds, hawthorn, Radix Rhapontici seu Radix Echinopsis, Angelica sinensis, rhizoma zingiberis, peach kernel, the radix paeoniae rubrathe, king are weighed by weight
Row is not stayed, is mixed, the water for adding 10 times of mixed material drug weight decocts 3 times, each 1h, and filtering, merging filtrate is simultaneously condensed into
Relative density is the medicinal extract B of 1.20-1.30 at 80 DEG C；
(3) 100 mesh sieves are crossed after pangolin is crushed, it is spare；
(4) extractum A, medicinal extract B are uniformly mixed, concentrate, be dried to dry extract, crushed, and the mixing of pangolin powder, Ran Houjia
Enter the starch of material medicine gross weight 20%, remix uniformly, pelletize, it is dry, to obtain the final product.
Relevant clinical data：
1st, case selection：
Select 160 clinical observations of postpartum (5-10 days) hypogalactia patient for making a definite diagnosis, patient, which is randomly divided into, treats 1-3 groups and right
According to organizing 4 groups, treatment group women 120, age 25-35 Sui, average age 28.9 years old, the course of disease most short person 5 days, most elder 8 days, puts down
Equal 6 days.Control group women 40, age 24-34 Sui, average age 28.2 years old, the course of disease most short person 5 days, most elder 10 days are average
7 days.The course of disease for the treatment of group and control group case, degrees of symptoms are basically identical, and no significant difference, is comparable.
2nd, therapeutic scheme：
Chinese medicine composition (embodiment 1-3) of the present invention is taken by treatment group, takes orally, one portion per day, point takes for each 1 time sooner or later；3
It is 1 course for the treatment of, 1 course for the treatment of of the lighter, 2 courses for the treatment of of severe one.Control group take granule for expelling obstruction of galactophore (radix astragali, prepared rhizome of rehmannia, the stem pith of the rice-paper plant, dianthus superbus,
Root of Chinese trichosanthes, play both sides of the street, Radix Rhapontici seu Radix Echinopsis, Radix Codonopsis, Angelica sinensis, Ligusticum wallichii, Radix Paeoniae Alba, the seed of cowherb, radix bupleuri, pangolin), by specification is taken.Clothes
During medicine daily observation cesarean lactation situation, during which lactation amount normally can withdrawal, after a week to result carry out statistical analysis.
3rd, efficacy determination：
(1) cure：Breast without distending pain, without enclosed mass, have rosy cheeks, spirit still, voice is loud and clear, and arteries and veins is strong, and sleep is normal,
Galactosis amount recovers normal.
(2) it is effective：Patient's malaise symptoms mitigate, and galactosis amount increases.
(3) it is invalid：Symptom is without change.
Total effective rate=cure rate+obvious effective rate
4th, result：
The result shows that the cure rate and total effective rate for the treatment of group illustrate Chinese medicine group of the invention obviously higher than control group
Puerpera lactagogue of the compound to initial stage in postpartum works well.
Model case is illustrated：
Case 1：Sun, female, 28 years old, Zhengzhou, henan people.5 days postpartum, during which household was that it has been looked for much also without lower breast
The recipe that stimulates the secretion of milk is eaten, but does not all have effect, takes Chinese medicine of the present invention, is taken orally, one portion per day, point is taken for each 1 time sooner or later, takes 2
After it, start lactation, after taking 5 days, galactosis amount recovers normal.Follow-up one month, puerpera's galactosis amount are normal.
Case 2：Zhang, female, 27 years old, Henan people from Jiaozhuo.3 days postpartum, without lower breast, massage lactagogue, milk were used in hospital
Still rare, 8 days postpartum started to take Chinese medicine of the present invention, took orally, one portion per day, took for each 1 time point sooner or later, after taking 3 days, breast
Juice secretory volume increases, and after taking 6 days, galactosis amount recovers normal.Follow-up one month, puerpera's galactosis amount are normal.
Case 3：Lee, female, 26 years old, the new village people in Henan.5 days postpartum is still dilute without lower breast, the oral tea that stimulates the secretion of milk, milk
Few, 10 days postpartum started to take Chinese medicine of the present invention, took orally, one portion per day, took for each 1 time point sooner or later, after taking 3 days, milk point
The amount of secreting increases, and after taking 5 days, galactosis amount recovers normal.Follow-up one month, puerpera's galactosis amount are normal.
Claims (8)
1. a kind of Chinese medicine composition suitable for puerpera's lactagogue at initial stage in postpartum, it is characterised in that including following material medicine：Ligusticum wallichii
5-15g, profound Hu 5-15g, stem pith of the rice-paper plant 5-15g, safflower 5-15g, dried orange peel 5-15g, radix glycyrrhizae 5-15g, rhizoma cyperi 5-15g, motherwort 10-
15g, fennel seeds 5-15g, hawthorn 20-30g, Radix Rhapontici seu Radix Echinopsis 20-25g, Angelica sinensis 5-8g, pangolin 20-40g, rhizoma zingiberis 5-15g, peach kernel 5-
15g, radix paeoniae rubrathe 20-30g, seed of cowherb 20-30g.
2. Chinese medicine composition according to claim 1, it is characterised in that including following material medicine：Ligusticum wallichii 5g, profound Hu
5g, stem pith of the rice-paper plant 5g, safflower 5g, dried orange peel 5g, radix glycyrrhizae 5g, rhizoma cyperi 5g, motherwort 10g, fennel seeds 5g, hawthorn 20g, Radix Rhapontici seu Radix Echinopsis 20g, Angelica sinensis
5g, pangolin 20g, rhizoma zingiberis 5g, peach kernel 5g, radix paeoniae rubrathe 20g, seed of cowherb 20g.
3. Chinese medicine composition according to claim 1, it is characterised in that including following material medicine：Ligusticum wallichii 10g, profound Hu
10g, stem pith of the rice-paper plant 10g, safflower 10g, dried orange peel 10g, radix glycyrrhizae 10g, rhizoma cyperi 10g, motherwort 12g, fennel seeds 10g, hawthorn 25g, Radix Rhapontici seu Radix Echinopsis
22g, Angelica sinensis 6g, pangolin 30g, rhizoma zingiberis 10g, peach kernel 10g, radix paeoniae rubrathe 25g, seed of cowherb 25g.
4. Chinese medicine composition according to claim 1, it is characterised in that including following material medicine：Ligusticum wallichii 15g, profound Hu
15g, stem pith of the rice-paper plant 15g, safflower 15g, dried orange peel 15g, radix glycyrrhizae 15g, rhizoma cyperi 15g, motherwort 15g, fennel seeds 15g, hawthorn 30g, Radix Rhapontici seu Radix Echinopsis
25g, Angelica sinensis 8g, pangolin 40g, rhizoma zingiberis 15g, peach kernel 15g, radix paeoniae rubrathe 30g, seed of cowherb 30g.
It is 5. a kind of such as the preparation method of claim 1-4 any one of them Chinese medicine compositions, it is characterised in that including following step
Suddenly：
(1) each material medicine is weighed by weight, is mixed, the water decoction of 10-15 times of addition mixed material drug weight 2-3 times, often
Secondary 1-1.5h, merges decocting liquid, freezes, and Chinese medicine freeze-dried powder is made；
(2) biofermentation is used, Chinese medicine freeze-dried powder is seeded in the mixed bacteria liquid of 10-20 times of weight, sealed fermenting 30-50h,
The mixed bacteria liquid includes：Bacillus subtilis 2 × 108Cfu/mL, Lactobacillus casei 3 × 108Cfu/mL, lactobacillus plantarum 2
×108Cfu/mL, bifidobacterium breve 1 × 108Cfu/mL, saccharomycete 1 × 108cfu/mL；
(3) by zymotic fluid after filtering, it is canned to obtain the final product.
It is 6. a kind of such as the preparation method of claim 1-4 any one of them Chinese medicine compositions, it is characterised in that to weigh by weight
Each material medicine, mixing, the water for adding 10-15 times of mixed material drug weight decoct 2-3 times, each 1-1.5h, merge decocting
Liquid.
It is 7. a kind of such as the preparation method of claim 1-4 any one of them Chinese medicine compositions, it is characterised in that including following step
Suddenly：
(1) Ligusticum wallichii, profound Hu, the stem pith of the rice-paper plant, safflower, dried orange peel are weighed by weight, is mixed, and add the body of 5-15 times of mixed material drug weight
The ethanol of product concentration 90%, refluxing extraction 2-3 times under the conditions of 70-80 DEG C, each 1-1.5h, filtering, merging filtrate is through decompression
Ethanol is recycled to no alcohol taste, and is condensed into the extractum A that relative density at 60 DEG C is 1.10-1.12；
(2) radix glycyrrhizae, rhizoma cyperi, motherwort, fennel seeds, hawthorn, Radix Rhapontici seu Radix Echinopsis, Angelica sinensis, rhizoma zingiberis, peach kernel, the radix paeoniae rubrathe, Wang Buliu are weighed by weight
OK, mix, the water for adding 10-15 times of mixed material drug weight decocts 2-3 times, each 1-1.5h, filtering, and merging filtrate is simultaneously dense
Shorten the medicinal extract B that relative density at 80 DEG C is 1.20-1.30 into；
(3) 100 mesh sieves are crossed after pangolin is crushed, it is spare；
(4) extractum A, medicinal extract B are uniformly mixed, concentrate, be dried to dry extract, crushed, and the mixing of pangolin powder, then add auxiliary
Material, remixes uniformly, pelletizes, dry, to obtain the final product.
8. preparation method according to claim 7, it is characterised in that the auxiliary material is starch, dextrin or white sugar, dosage
For the 20-30% of material medicine gross weight.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110613810A (en) * | 2019-11-04 | 2019-12-27 | 迪国生物高科技有限公司 | Traditional Chinese medicine composition for conditioning sub-health and preparation method thereof |
| CN114848767A (en) * | 2022-05-11 | 2022-08-05 | 江西瑭玖电子商务有限公司 | Herbal fermented traditional Chinese medicine nursing patch and preparation method thereof |
-
2018
- 2018-02-06 CN CN201810118946.6A patent/CN107998366A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110613810A (en) * | 2019-11-04 | 2019-12-27 | 迪国生物高科技有限公司 | Traditional Chinese medicine composition for conditioning sub-health and preparation method thereof |
| CN114848767A (en) * | 2022-05-11 | 2022-08-05 | 江西瑭玖电子商务有限公司 | Herbal fermented traditional Chinese medicine nursing patch and preparation method thereof |
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