CN101259178A - Chinese medicine preparation for treating rheumatoid arthritis - Google Patents
Chinese medicine preparation for treating rheumatoid arthritis Download PDFInfo
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- CN101259178A CN101259178A CNA200810103707XA CN200810103707A CN101259178A CN 101259178 A CN101259178 A CN 101259178A CN A200810103707X A CNA200810103707X A CN A200810103707XA CN 200810103707 A CN200810103707 A CN 200810103707A CN 101259178 A CN101259178 A CN 101259178A
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- rhizoma
- rheumatoid arthritis
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Abstract
The invention relates to a Chinese medicine preparation used for treating wangbi, which adopts more than 10 Chinese herbal medicines as raw materials, including peach seed, safflower, ground beetle and rhizoma corydalis, etc. The invention has the functions of expelling wind, clearing away cold, treating arthralgiasyndrome and eliminating pain. The invention is developed on the basis of traditional Chinese medicine differentiation treatment and combined with the latest achievements in scientific research. The Chinese medicine preparation used for treating wangbi has the advantages of curative effect, no side effects, innocuity, low price, which is safe and easy to use.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of rheumatoid arthritis, is that a kind of rheumatoid arthritis for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Rheumatoid arthritis be by the wind-cold damp pathogen visitor in the joint, QI and blood numbness resistance, cause with little arthralgia, swelling, morning deadlock be the disease of characteristics.Be equivalent to rheumatoid arthritis.The major lesions of rheumatoid arthritis is at Liver and kidney.How because of innate deficiency, or caused by liver and kidney deficiency due to prolonged illness, the exhaustion due to sexual indulgence etc., exopathogen invade and, go deep into muscles and bones; Or the sick delay of numbness is difficult, and with the passing of time weakened body resistance, the expectorant stasis of blood is condensed, and gives up in Liver and kidney to form.The primary disease course of disease with the passing of time, the time time slack anxious, gradually serious, cure difficulty.Clinically must catch suffering from a deficiency of the kidney cold the Sheng, the agglutinating characteristics of the expectorant stasis of blood are carried out the kidney invigorating cold relieving, pick the expectorant blood stasis dispelling.If when mark heat symptom-complex shape occurring, can help with heat clearing away, note nourishing the liver blood simultaneously, protect taste.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as wind-cold-damp retention card, rheumatic fever melancholia, syndrome of intermin-gled phlegm and blood stasis, the coagulated cold syndrome of suffering from a deficiency of the kidney, syndrome of yin deficiency of liver and kidney, deficiency of qi and blood card clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of rheumatoid arthritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
0.1～2 part of 0.1～2 part of Olibanum of 1.0～4 portions of Rhizoma Et Radix Notopterygiis of Radix Angelicae Sinensis
0.1～2 part of 0.1～2 part of Radix Aucklandiae of 1.0～4 parts of Radix Angelicae Pubescentiss of Rhizoma Corydalis
0.1～2 part in 0.1～2 part of Semen Persicae of 0.1～2 portion of Radix Gentianae Macrophyllae of Eupolyphaga Seu Steleophaga
0.1～1 part of 0.1～2 portion of Scorpio of 0.1～2 part of Rhizoma Chuanxiong of Flos Carthami.
The weight proportion of each crude drug of optimization formula of the present invention is:
0.5～1.5 part of 0.5～1.5 part of Olibanum of 1.5～2.5 portions of Rhizoma Et Radix Notopterygiis of Radix Angelicae Sinensis
0.5～1.5 part of 0.5～1.5 part of Radix Aucklandiae of 1.5～2.5 parts of Radix Angelicae Pubescentiss of Rhizoma Corydalis
0.5～1.5 part in 0.5～1.5 part of Semen Persicae of 0.5～1.5 portion of Radix Gentianae Macrophyllae of Eupolyphaga Seu Steleophaga
0.3～0.7 part of 0.5～1.5 portion of Scorpio of 0.5～1.5 part of Rhizoma Chuanxiong of Flos Carthami.
The weight proportion of each crude drug of optimum formula of the present invention is:
1 part of 1 part of Olibanum of 2 portions of Rhizoma Et Radix Notopterygiis of Radix Angelicae Sinensis
1 part of 1 part of Radix Aucklandiae of 2 parts of Radix Angelicae Pubescentiss of Rhizoma Corydalis
1 part in 1 part of Semen Persicae of 1 portion of Radix Gentianae Macrophyllae of Eupolyphaga Seu Steleophaga
0.5 part of 1 portion of Scorpio of 1 part of Rhizoma Chuanxiong of Flos Carthami.
Drug action mechanism among the present invention is as follows:
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Corydalis property of medicine suffering, hardship, temperature.GUIXIN, liver, spleen channel.Has promoting blood circulation to remove blood stasis, the effect of promoting the circulation of QI to relieve pain.Can treat obstruction of qi in the chest and cardialgia, epigastric pain, lumbago, colicky, dysmenorrhea, amenorrhea ， mass in the abdomen, the stasis of blood stagnated and suffered from abdominal pain traumatic injury etc. puerperal.(the 1261st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Eupolyphaga Seu Steleophaga nature and flavor are salty, cold, slightly poisonous.Return Liver Channel.Has promoting blood circulation to remove blood stasis, inducing menstruation to relieve menalgia, the abdominal mass that disappears, the effect of reunion of bone.Can treat cervical cancer, multiple myeloma, various tumors such as leukemia; And be used for lump in the abdomen, and amenorrhea due to stagnation of blood, postnatal blood stasis stomachache, traumatic injury, swollen and rigid tongue, congenital deformity of the tongue, the muscles and bones folding is hindered hepatosplenomegaly, an emaciation due to blood disorder, scarlet fever, erysipelas etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 91st page).
Flos Carthami property of medicine suffering, temperature.GUIXIN, Liver Channel.Has promoting blood circulation to restore menstrual flow, the effect of stasis-dispelling and pain-killing.Can treat the blood stasis amenorrhea, dysmenorrhea, postpartum stagnation stomachache, obstruction of qi in the chest and cardialgia ， mass in the abdomen knot is poly-, traumatic injury, arthralgia, apoplectic hemiplegia, macule etc.(the 2763rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Et Radix Notopterygii property of medicine suffering, hardship, temperature.Return bladder, kidney channel.Has diffusing exterior cold, wind-damp dispelling, sharp joint, analgesic effect.Can treat affection of exogenous wind-cold, it is lossless to have a headache, anemofrigid-damp arthralgia, edema due to wind pathogen edema, sore swollen toxin etc.(the 1621st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Angelicae Pubescentis property of medicine hardship, suffering, tepor.Return kidney, urinary bladder channel.Has expelling wind and dampness, the effect of dispersing cold for relieving pain.Can treat anemofrigid-damp arthralgia, lumbocrural pain, headache toothache etc.(the 2389th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Gentianae Macrophyllae property of medicine hardship, suffering are slightly cold.Return stomach, liver, gallbladder meridian.Has wind-damp dispelling, clearind deficient heat, the effect of jaundice eliminating.Can treat rheumatic arthralgia, muscles and bones contracture, hands and feet caused by paralysis, osteopyrexia and fever, children's's infantile malnutrition with fever, jaundice due to damp-heat etc.(the 2469th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Olibanum property of medicine suffering, hardship, temperature.GUIXIN, liver, spleen channel.Have and invigorate blood circulation, circulation of qi promoting, analgesic effect.Can treat trusted subordinate's pain, amenorrhea, dysmenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, traumatic injury stasis of blood pain, swollen ulcer drug, the sore being festered and unhealed etc.(the 1992nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Aucklandiae property of medicine suffering, hardship, temperature.Return spleen, stomach, liver, lung meridian.Have promoting the circulation of QI to relieve pain, the effect of mediation intestinal stasis relieving.Can treat fullness and distention in the chest and hypochondrium, abdominal distention, vomiting is had loose bowels, and heavily waits after the dysentery.(the 480th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Persicae property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Scorpio nature and flavor suffering, flat; Poisonous.Return Liver Channel.Has endogenous wind stopping spasmolytic, dispersing pathogen accumulation, the effect of removing obstruction in the collateral to relieve pain.Can treat infantile convulsion, tic spasm, middle air port
, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula etc.(the 111st page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis and Radix Gentianae Macrophyllae; With Radix Angelicae Sinensis, Olibanum, Rhizoma Corydalis, Semen Persicae, Flos Carthami and Eupolyphaga Seu Steleophaga is ministerial drug; With Rhizoma Chuanxiong, the Radix Aucklandiae and Scorpio is adjuvant.All medicines are harmonious, and are total to the tool expelling wind and cold, the effect of numbness relieving and pain relieving.The treatment rheumatoid arthritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment rheumatoid arthritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat rheumatoid arthritis, and the prevention of rheumatoid arthritis is also had good effect, and the treatment rheumatoid arthritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment rheumatoid arthritis; Treatment rheumatoid arthritis patient 47 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.34 examples of fully recovering account for 72.34%, and 9 examples that take a turn for the better account for 19.15%, and more 4 examples do not account for 8.51%, and total effective rate reaches 91.49%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 decoction is pressed following weight weighting raw materials:
1 part of 1 part of Olibanum of 2 portions of Rhizoma Et Radix Notopterygiis of Radix Angelicae Sinensis
1 part of 1 part of Radix Aucklandiae of 2 parts of Radix Angelicae Pubescentiss of Rhizoma Corydalis
1 part in 1 part of Semen Persicae of 1 portion of Radix Gentianae Macrophyllae of Eupolyphaga Seu Steleophaga
0.5 part of 1 portion of Scorpio of 1 part of Rhizoma Chuanxiong of Flos Carthami.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment rheumatoid arthritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Embodiment 2 capsules are pressed following weight weighting raw materials:
1 part of 1 part of Olibanum of 2 portions of Rhizoma Et Radix Notopterygiis of Radix Angelicae Sinensis
1 part of 1 part of Radix Aucklandiae of 2 parts of Radix Angelicae Pubescentiss of Rhizoma Corydalis
1 part in 1 part of Semen Persicae of 1 portion of Radix Gentianae Macrophyllae of Eupolyphaga Seu Steleophaga
0.5 part of 1 portion of Scorpio of 1 part of Rhizoma Chuanxiong of Flos Carthami.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, drying, be ground into fine powder, incapsulate.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, two 2 to three times on the one, three months is a course of treatment.
Claims (3)
1, a kind of Chinese medicine preparation for the treatment of rheumatoid arthritis is characterized in that it is made by following raw materials by weight proportions:
0.1～2 part of 0.1～2 part of Olibanum of 1.0～4 portions of Rhizoma Et Radix Notopterygiis of Radix Angelicae Sinensis
0.1～2 part of 0.1～2 part of Radix Aucklandiae of 1.0～4 parts of Radix Angelicae Pubescentiss of Rhizoma Corydalis
0.1～2 part in 0.1～2 part of Semen Persicae of 0.1～2 portion of Radix Gentianae Macrophyllae of Eupolyphaga Seu Steleophaga
0.1～1 part of 0.1～2 portion of Scorpio of 0.1～2 part of Rhizoma Chuanxiong of Flos Carthami.
2, a kind of Chinese medicine preparation for the treatment of rheumatoid arthritis according to claim 1, wherein the weight proportion of each crude drug is:
0.5～1.5 part of 0.5～1.5 part of Olibanum of 1.5～2.5 portions of Rhizoma Et Radix Notopterygiis of Radix Angelicae Sinensis
0.5～1.5 part of 0.5～1.5 part of Radix Aucklandiae of 1.5～2.5 parts of Radix Angelicae Pubescentiss of Rhizoma Corydalis
0.5～1.5 part in 0.5～1.5 part of Semen Persicae of 0.5～1.5 portion of Radix Gentianae Macrophyllae of Eupolyphaga Seu Steleophaga
0.3～0.7 part of 0.5～1.5 portion of Scorpio of 0.5～1.5 part of Rhizoma Chuanxiong of Flos Carthami.
3, a kind of Chinese medicine preparation for the treatment of rheumatoid arthritis according to claim 1, wherein the weight proportion of each crude drug is:
1 part of 1 part of Olibanum of 2 portions of Rhizoma Et Radix Notopterygiis of Radix Angelicae Sinensis
1 part of 1 part of Radix Aucklandiae of 2 parts of Radix Angelicae Pubescentiss of Rhizoma Corydalis
1 part in 1 part of Semen Persicae of 1 portion of Radix Gentianae Macrophyllae of Eupolyphaga Seu Steleophaga
0.5 part of 1 portion of Scorpio of 1 part of Rhizoma Chuanxiong of Flos Carthami.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA200810103707XA CN101259178A (en) | 2008-04-10 | 2008-04-10 | Chinese medicine preparation for treating rheumatoid arthritis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA200810103707XA CN101259178A (en) | 2008-04-10 | 2008-04-10 | Chinese medicine preparation for treating rheumatoid arthritis |
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| CN101259178A true CN101259178A (en) | 2008-09-10 |
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| CNA200810103707XA Pending CN101259178A (en) | 2008-04-10 | 2008-04-10 | Chinese medicine preparation for treating rheumatoid arthritis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102512523A (en) * | 2011-12-30 | 2012-06-27 | 山西振东开元制药有限公司 | Medicine for treating rheumatoid arthritis |
| CN106421166A (en) * | 2016-11-09 | 2017-02-22 | 佘鹏 | Traditional Chinese medicine for treating Wangbi and preparation method thereof |
-
2008
- 2008-04-10 CN CNA200810103707XA patent/CN101259178A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102512523A (en) * | 2011-12-30 | 2012-06-27 | 山西振东开元制药有限公司 | Medicine for treating rheumatoid arthritis |
| CN106421166A (en) * | 2016-11-09 | 2017-02-22 | 佘鹏 | Traditional Chinese medicine for treating Wangbi and preparation method thereof |
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Open date: 20080910 |