CN102512523A - Medicine for treating rheumatoid arthritis - Google Patents

Medicine for treating rheumatoid arthritis Download PDF

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Publication number
CN102512523A
CN102512523A CN201110454403XA CN201110454403A CN102512523A CN 102512523 A CN102512523 A CN 102512523A CN 201110454403X A CN201110454403X A CN 201110454403XA CN 201110454403 A CN201110454403 A CN 201110454403A CN 102512523 A CN102512523 A CN 102512523A
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China
Prior art keywords
medicine
rheumatoid arthritis
treating
medicinal powder
treatment
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Pending
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CN201110454403XA
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Chinese (zh)
Inventor
范平安
王六贵
吕建英
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Shanxi Zhendong Kaiyuan Pharmaceutical Co Ltd
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Shanxi Zhendong Kaiyuan Pharmaceutical Co Ltd
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Application filed by Shanxi Zhendong Kaiyuan Pharmaceutical Co Ltd filed Critical Shanxi Zhendong Kaiyuan Pharmaceutical Co Ltd
Priority to CN201110454403XA priority Critical patent/CN102512523A/en
Publication of CN102512523A publication Critical patent/CN102512523A/en
Pending legal-status Critical Current

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Abstract

A medicine for treating rheumatoid arthritis is prepared by uniformly mixing Cibotium barometz, Scorpion, Eupolyphaga, anise, Gentiana macrophylla, Radix Saposhnikoviae, Notopterygium, peach kernel and safflower which are carefully selected and washed by water, crushing the mixture into 100-120-mesh medicinal powder, disinfecting and sterilizing the medicinal powder, and preparing the medicinal powder into a water pill product by using a bonding agent according to a conventional method. The medicine for treating the rheumatoid arthritis has the effects of expelling wind, dredging meridians, promoting blood circulation, warming menstruation, expelling cold, nourishing bones and tonifying Yang, has a good effect on treating the rheumatoid arthritis and has no toxic side effect.

Description

A kind of medicine of treating rheumatic arthritis
Technical field
The present invention relates to a kind of medicine of treating rheumatic arthritis, especially relating to a kind of is the medicine of the treatment rheumatic arthritis of crude drug preparation with Chinese medicine.
Background technology
Rheumatic arthritis is a kind of common acute or chronic ICT.Can show effect repeatedly and involve heart.Clinical miserable with joint and muscle the. fugitive, heavily work, pain is characteristic.Belong to allergic disease.Be one of main performance of rheumatic fever, how with febris acuta and arthralgia onset.Onset is early stage how similar with anemofrigid cold, is difficult for being paid attention to by people, mainly shows as waist and lower limb and sends out cold, aversion to wind, pain; The chance cold rnning is acute, and activity is stretched pain in the wrong not freely; Like untimely treatment; How to the later stage joint deformity, pain unbearably and cause the disease of heart kidney is in the misery patient for a long time.
Anti-inflammation analgesic, hormone medicine are used in the treatment of rheumatic arthritis more, but can not be effected a radical cure, and take said medicine for a long time, side effect is big at present.
Summary of the invention
The purpose of this invention is to provide a kind of is the medicine of the treatment rheumatic arthritis of crude drug preparation with Chinese medicine, this medicine with dispelling wind and removing obstruction in the collateral, invigorate blood circulation, dispelling cold by warming the meridian, the tonifying YANG of benefit bone be the principle treatment, therapeutic effect is good, expense is low.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Rhizoma Cibotii 5~7 Scorpios 5~7 Eupolyphaga Seu Steleophagas 5~7 Fructus Anisi Stellatis 4~8 Radix Gentianae Macrophyllae 5~8
Windproof 5~7 Rhizoma Et Radix Notopterygiis, 4~7 Semen Persicaes, 5~7 Flos Carthamis 4~7.
The medicine of above-mentioned each component can be processed said peroral dosage form on any pharmaceuticss such as tablet, pill, powder, capsule, and the preferred dosage form of the present invention is a water pill.
The concrete method for preparing of medicine water pill of the present invention agent is: said medicine by said parts by weight mix homogeneously, is ground into 100~120 purpose medicated powder, and sterilization uses binding agent to make the water pill product by conventional method.
In the prescription of the present invention, Rhizoma Cibotii invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling; The active blood stasis dispelling of Scorpio, the endogenous wind stopping relieving convulsion; The Eupolyphaga Seu Steleophaga removing blood stasis; The Fructus Anisi Stellati dispersing cold for relieving pain; Radix Gentianae Macrophyllae wind-damp dispelling, Shujin network; Windproof expelling wind and removing dampness; Notopterygium wind dispelling blood stasis dispelling, pain relieving; Semen Persicae blood circulation promoting and blood stasis dispelling, pain relieving; Flos Carthami blood circulation promoting and blood stasis dispelling, pain relieving.All medicines share, and can play dispelling wind and removing obstruction in the collateral, invigorate blood circulation, the effect of dispelling cold by warming the meridian, the tonifying YANG of benefit bone, and are evident in efficacy to treatment rheumatic arthritis, and cheap.
For further investigating the clinical efficacy of Drug therapy rheumatic arthritis of the present invention, select 63 routine rheumatic arthritis patients to carry out clinical observation on the therapeutic effect.
Be divided into treatment group and matched group to 63 routine patients, 30 people are organized in treatment, matched group 33 people.
All case is all according to the diagnosis basis in " new Chinese medicine clinical research guideline (first volume) ":
(1) clinical manifestation: the streptococcal infection medical history is arranged more; Acute stage, can have multiple and the the. fugitive joint aches, mostly occurs in big joint, can be with redness pain or tuberosity or erythema; Chronic phase, can only be felt joint aches;
(2) laboratory examination: anti-" O " is more than 1:500; Or erythrocyte sedimentation rate speeds; Or antistreptokinase surpasses more than 80 units; Or antihyaluronidase is more than 128 units; Or C reflection protein positive;
(3) X-ray film does not have the sclerotin damage.
Be diagnosed as rheumatic arthritis.
Therapeutic Method
Matched group adopts ibuprofen, every day 1 time, one time 2;
The treatment group adopts water pill drug form of the present invention, every day 2 times, each 10 grams.
Before and after the treatment, treatment group and the matched group patient chamber of experimentizing each parameter of inspection are seen table 1:
The variation of each parameter before and after the table 1 rheumatic arthritis patient treatment
Figure 453910DEST_PATH_IMAGE001
Criterion of therapeutical effect
Criterion of therapeutical effect with reference to " new Chinese medicine clinical research guideline (first volume) ".Cure: the arthralgia of getting involved after the treatment disappears, and function of joint is improved or recovered normal, and it is normal that erythrocyte sedimentation rate, rheumatoid factor have been recovered; Produce effects: the arthralgia of getting involved is clearly better or disappears, and erythrocyte sedimentation rate, rheumatoid factor titre reduce, or has recovered normal, but arthroncus does not disappear as yet; Effectively: the arthralgia of getting involved after the treatment or swell and ache and take a favorable turn; Invalid: with compare each side and do not have progress before the treatment.
Two groups of case treatment back curative effect comparative results are seen table 2.
Table 2 liang group case treatment back curative effect relatively
Group The example number Cure n (%) Effective n (%) Invalid n (%) Total effective rate n (%)
Matched group 33 11(33.3) 14(42.5) ?8(24.2) 25(75.8)
The treatment group 30 17(56.7) 9(30) 4(13.3) 26(86.7)
The specific embodiment
Embodiment 1
Get Rhizoma Cibotii 50g, Scorpio 50g, Eupolyphaga Seu Steleophaga 50g, Fructus Anisi Stellati 40g, Radix Gentianae Macrophyllae 50g, windproof 50g, Rhizoma Et Radix Notopterygii 40g, Semen Persicae 50g, Flos Carthami 40g mix homogeneously selected, that clear water is cleaned; Be ground into 100~120 medicated powder, sterilization uses binding agent to make the water pill product by conventional method.
Embodiment 2
Get Rhizoma Cibotii 70g, Scorpio 70g, Eupolyphaga Seu Steleophaga 70g, Fructus Anisi Stellati 80g, Radix Gentianae Macrophyllae 80g, windproof 70g, Rhizoma Et Radix Notopterygii 70g, Semen Persicae 70g, Flos Carthami 70g mix homogeneously selected, that clear water is cleaned, be ground into 100~120 medicated powder, sterilization makes the powder product.

Claims (2)

1. medicine of treating rheumatic arthritis is that crude drug prepares by the Chinese medicine of following portions by weight:
Rhizoma Cibotii 5~7 Scorpios 5~7 Eupolyphaga Seu Steleophagas 5~7
Fructus Anisi Stellati 4~8 Radix Gentianae Macrophyllae 5~8 windproof 5~7
Rhizoma Et Radix Notopterygii 4~7 Semen Persicaes 5~7 Flos Carthamis 4~7.
2. the medicine of treatment rheumatic arthritis according to claim 1 is characterized in that said medicine is processed the water pill dosage form.
CN201110454403XA 2011-12-30 2011-12-30 Medicine for treating rheumatoid arthritis Pending CN102512523A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201110454403XA CN102512523A (en) 2011-12-30 2011-12-30 Medicine for treating rheumatoid arthritis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201110454403XA CN102512523A (en) 2011-12-30 2011-12-30 Medicine for treating rheumatoid arthritis

Publications (1)

Publication Number Publication Date
CN102512523A true CN102512523A (en) 2012-06-27

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CN201110454403XA Pending CN102512523A (en) 2011-12-30 2011-12-30 Medicine for treating rheumatoid arthritis

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CN (1) CN102512523A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102764350A (en) * 2012-07-17 2012-11-07 遵义臻坤中草医药研究所 Chinese medicinal composition for treating rheumatoid bone diseases and arthralgia

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101259178A (en) * 2008-04-10 2008-09-10 北京万寿通医药科技有限公司 Chinese medicine preparation for treating rheumatoid arthritis
CN101683400A (en) * 2008-09-22 2010-03-31 赵保云 Preparation method of pill for treating three kinds of spinal arthralgia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101259178A (en) * 2008-04-10 2008-09-10 北京万寿通医药科技有限公司 Chinese medicine preparation for treating rheumatoid arthritis
CN101683400A (en) * 2008-09-22 2010-03-31 赵保云 Preparation method of pill for treating three kinds of spinal arthralgia

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102764350A (en) * 2012-07-17 2012-11-07 遵义臻坤中草医药研究所 Chinese medicinal composition for treating rheumatoid bone diseases and arthralgia

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Application publication date: 20120627