CN100571770C - A kind of Chinese medicine cutaneous permeable agent - Google Patents

A kind of Chinese medicine cutaneous permeable agent Download PDF

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CN100571770C
CN100571770C CNB200710011734XA CN200710011734A CN100571770C CN 100571770 C CN100571770 C CN 100571770C CN B200710011734X A CNB200710011734X A CN B200710011734XA CN 200710011734 A CN200710011734 A CN 200710011734A CN 100571770 C CN100571770 C CN 100571770C
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radix
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CN101085327A (en
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王敏
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Abstract

The invention discloses a kind of Chinese medicine cutaneous permeable agent, it is made by the raw material of following parts by weight: Olibanum 10-20 part, Myrrha 10-20 part, Flos Carthami 10-20 part, Rhizoma Zingiberis 10-20 part, Radix Angelicae Pubescentis 10-20 part, Fructus Zanthoxyli 10-20 part, Sanguis Draxonis 5-10 part, Pericarpium Citri Reticulatae 10-20 part, Herba Menthae 10-20 part, Radix Aconiti 10-20 part, Radix Aconiti Kusnezoffii 10-20 part, Radix Glycyrrhizae 10-20 part, Rhizoma Homalomenae 10-20 part, Herba speranskiae tuberculatae 10-20 part, Herba Lycopodii 10-20 part.This medicine instant effect, curative effect is obvious, cure rate is high.Cutaneous permeable agent can be directly to reach diseased region, without the first pass effect of liver, gastrointestinal tract is not had any stimulation and avoided the destruction of digestive enzymes to medicine, be applied to and reach expelling wind and activating blood circulation on the skin, promote vasodilation, promote sweat gland secretion, make body heat radiation increase, impel blood circulation, dredging the meridian, blood circulation promoting and blood stasis dispelling, the cold expelling that induces sweat, thus the active cell activity.

Description

A kind of Chinese medicine cutaneous permeable agent
Technical field
The present invention relates to a kind of Chinese medicine, is various pain and soft tissue injury external used medicine that bone disease such as a kind of main treatment migratory arthralgia, arthralgia due to cold, arthralgia chiefly caused by damp pathogen, hyperosteogeny, cervical spondylosis, lumbar spondylosis, lumbar intervertebral disc prolapse, scapulohumeral periarthritis, spinal canal stenosis and wind, cold, wet, expectorant, the stasis of blood cause specifically.
Background technology
The present medicine for external use of the various pain that cause of treatment bone disease and wind, cold, wet, expectorant, the stasis of blood, curative effect is slower, as make the patient can not feel definite curative effect at the initial stage of a disease, the patient is lost the confidence to medicine for external use, but some disease is shown effect repeatedly as diseases such as prolapse of lumbar intervertebral disc, hyperosteogenys, the oral medicine effect is not remarkable yet, and takes medicine for a long time patient's Liver and kidney is all had harmful effect.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine cutaneous permeable agent, it directly is applied to the affected part, and curative effect is rapid, effective percentage, cure rate height.
Technical scheme of the present invention is as follows:
Medicine of the present invention is made by the raw material of following parts by weight:
Olibanum 10-20 part, Myrrha 10-20 part, Flos Carthami 10-20 part, Rhizoma Zingiberis 10-20 part, Radix Angelicae Pubescentis 10-20 part, Fructus Zanthoxyli 10-20 part, Sanguis Draxonis 5-10 part, Pericarpium Citri Reticulatae 10-20 part, Herba Menthae 10-20 part, Radix Aconiti 10-20 part, Radix Aconiti Kusnezoffii 10-20 part, Radix Glycyrrhizae 10-20 part, Rhizoma Homalomenae 10-20 part, Herba speranskiae tuberculatae 10-20 part, Herba Lycopodii 10-20 part.
The further scheme of said medicine is:
20 parts of Olibanums, 20 parts of Myrrhas, 20 parts on Flos Carthami, 20 parts of Rhizoma Zingiberiss, 20 parts of Radix Angelicae Pubescentiss, 20 parts of Fructus Zanthoxylis, 7 parts of Sanguis Draxonis, 20 parts of Pericarpium Citri Reticulataes, 10 parts of Herba Menthaes, 10 parts of Radix Aconitis, 10 parts of Radix Aconiti Kusnezoffii, 20 parts in Radix Glycyrrhizae, 20 parts of Rhizoma Homalomenaes, 20 parts of Herba speranskiae tuberculataes, 20 parts of Herba Lycopodiis.
Above Chinese herbal medicine mixed to put add the above Chinese liquor 500---1000 part of 50 degree in the container, in two to three weeks of dipping, get filter paper and leach medicinal liquid and promptly make Chinese medicine cutaneous permeable agent of the present invention.
Using method: this medicine 7 days was a course of treatment, and general state of an illness medication can be healed in 7 days entirely, and heavy then is two to three courses of treatment.The state of an illness according to the patient is applied to affected part or sore place, applies to the affected part in order to make the Chinese medicine cutaneous permeable agent can absorb the reuse plastic sheeting fully with 3 to 5 milliliters of 5 milliliters of syringes extractions, takes off after 30 minutes and both can.
Injure the careful usefulness of ethanol allergy sufferers outward..
Cutaneous permeable agent of the present invention is as in conjunction with acupuncture and moxibustion treatment, HUOLONG therapy, transdermal administration therapy, scrape therapy, midnight-noon and ebb-flow doctrine therapy, general designation " the holographic therapy of 5 dimensions " better effects if.Also can combination physical therapy, electrotherapy, thermotherapy can rapider faster its therapeutic effect of bringing into play more efficiently.
The clinical practice of Chinese medicine cutaneous permeable agent of the present invention by 8 years, proved this medicine to migratory arthralgia, arthralgia due to cold, arthralgia chiefly caused by damp pathogen, hyperosteogeny, cervical spondylosis, lumbar spondylosis, prolapse of lumbar intervertebral disc, scapulohumeral periarthritis, spinal canal stenosis, numb limbs and tense tendons, ankylosing spondylitis, rheumatic arthritis, sprain, various pain and soft tissue injury that aseptic inflammation such as acute and chronic lumbar soft tissue injury and wind, cold, wet, expectorant, the stasis of blood cause be evident in efficacy.Cutaneous permeable agent of the present invention can also be treated the pain of cyclomastopathy, urethritis, cystitis, prostatitis, adnexitis, pelvic inflammatory disease, chronic appendicitis, gastroenteritis and various unknown causes.
Skin is in the metabolism organ, skin of human body maximum tissues such as hair follicle, sweat gland to be arranged, and is the table of the whole body, has the defence exopathogen, drains the effect of perspiration, regulate body temperature assisted respiartion.
Chinese medicine transdermal administration system belongs to external treatment of Chinese medicine, and is in the existing long history of China, just on the books in " interior warp ".The same with the internal treatment, all be that organic conception and determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs thought with the traditional Chinese medical science is guidance, use various method medicine to be imposed on positions such as skin, hole key, acupuncture points on the human body, to bring into play effects such as its dredging the meridian, QI and blood regulating, eliminating toxic substances to remove stasis, strengthening vital QI to eliminate pathogenic factors, make unbalanced internal organs negative and positive be readjusted and improve, thereby promote the recovery of body function, reach the purpose of curing the disease.The Chinese end Huatuo then have specially and state " inside and outside controls ", in Song dynasty " formulary of peaceful benevolent dispensary " detailed argumentation arranged again.As seen Chinese medical theory has been established theoretical basis already for the research of Chinese medicine transdermal drug delivery system.
The invention has the advantages that: 1, scientific formulation rationally, the medicine source is abundant, not only met reason, method, side, the medicine of the traditional Chinese medical science but also modern medicine is arranged and the pharmacology is foundation.Instant effect, curative effect is obvious, cure rate is high sees Table 1.2, the characteristics of transdermal administration be medicine can be directly to reach diseased region, without the first pass effect of liver, gastrointestinal tract is not had any stimulation and has avoided the destruction of digestive enzymes to medicine.The misery of taking medicine, having an injection is avoided in the medicine external, and usage is simple.4, medicine can pass through dermal osmosis rapidly, efficiently, and reach expelling wind and activating blood circulation, promote vasodilation, promote sweat gland secretion, make the body heat radiation increase, impel blood circulation, dredging the meridian, blood circulation promoting and blood stasis dispelling, the cold expelling that induces sweat, thus the active cell activity.5, regulate neural, as to regulate internal organs, adjustment, putrefaction removing and tissue regeneration promoting, enhancing cell differentiation and proliferation, body had no side effect also can repair the enhancing human body immunity system, recover body health.
Observation on Clinical Application:
This group patient 463 people, wherein male 311 people, women 152 people.Maximum 72 years old age, minimal ages 18 years old, the course of disease is the longest 12 years, the shortest 3 months; diseased region: cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, rheumatic arthritis, sciatica, numb limbs and tense tendons, women's puerperal exposure to wind, hyperosteogeny 181 people; cyclomastopathy, hysteromyoma, adnexitis, prostatitis, prostatic hyperplasia, prostate hyperplasia 192 people, other disease 90 people, all cases all through B ultrasonic, X sheet, CT, clarify a diagnosis.
Table 1 medicine group of the present invention is treated 463 routine patient's curative effect tables:
Project Recovery from illness Produce effects Effectively Invalid Effectively total
The example number 268 128 38 29 434
Ratio 57.88% 27.65% 8.21% 6.26% 93.74%
The medicine for external use osteodynia spirit tincture that contrast selects for use Kunming Yunnan red tea Pharmaceutical to produce, number of users is 30 people, treatment bone disease, general week absorption antiinflammatory, it is slow than medicine of the present invention slowly to take effect, and cutaneous permeable agent of the present invention can be fully recovered to a week of mild symptoms.
Pharmacological action according to theoretical each component of this cutaneous permeable agent of Chinese medicine:
Olibanum: the acrid in the mouth hardship, warm in nature.The effect of blood circulation promoting regulates qi, pain relieving granulation promoting is arranged, especially with stop in the chest and abdomen swelling and pain due to the QI and blood retardance, the women's blood stasis, diseases such as amenorrhea, dysmenorrhea treat with this product, curative effect is fine.
Myrrha: bitter in the mouth, property is flat.Can control traumatic injury, the blood stasis of surgery carbuncle skin infection and traumatology has a pain.Because this product has the function of removing blood stasis, so control not all right, the amenorrhea of women's blood stasis again.
Flos Carthami: acrid in the mouth, warm in nature.The hot temperature of loosing leads to, have invigorate blood circulation, the effect of clots absorbing blood, can eliminate the heating that causes because of blood stasis.Many with can clots absorbing blood, logical menstruation, be applicable to the amenorrhea, difficult labour or the postpartum stagnation stomachache that cause because of blood stasis is not all right and traumatic injury blood stasis disease such as have a pain.
Rhizoma Zingiberis: acrid in the mouth, hot in nature.The effect of separating dispersing wind and cold and warming middle-JIAO recuperating depleted YANG is arranged, can control the yang deficiency of anemofrigid cold and cold extremities faint pulse and desire to take off disease.
Radix Angelicae Pubescentis: acrid in the mouth hardship, slightly warm in nature.The effect of delivering the wind dehumidifying of loosing is arranged, " arthralgia chiefly caused by damp pathogen " disease that control the dumb and heavy numbness of lower limb foot acid of the neck that causes because of rheumatism, pain, can not walk.Other various rheumatism, using this product also has better curative effect.
Fructus Zanthoxyli: acrid in the mouth, hot in nature.Have the kidney warming warm up spleen, by the effect of cold dampness.
Sanguis Draxonis: sweet-salty, property is flat, is the key medicine of traumatology and surgery.
Pericarpium Citri Reticulatae: the acrid in the mouth hardship, warm in nature.Xin Nenghang looses, dispelling the damp pathogen with bitter and warm drugs, and the effect of regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm is arranged.
Herba Menthae: acrid in the mouth, cool in nature.The effect of antiinflammatory, pain relieving, antipruritic, antibacterial, clearing away upper-jiao heat is arranged.
Radix Aconiti: acrid in the mouth, extremely hot in nature.Suffering is loose and is walked to scurry, and gos deep into bone marrow, can search the wind and cold in the muscles and bones of loosing, and controls anemofrigid-damp arthralgia arthralgia or numbness.It is broken the medicine that cold is gathered, so can control the colic of cold type that coldness and pain in the epigastrium and testis are had a pain and connected and lack abdomen again.
Radix Aconiti Kusnezoffii: nature and flavor are hot.The effect that dispersing cold for relieving pain is arranged, search wind prevailing over dampness, diseases such as energy dispelling the wind and dampness pathogens, paralysis, pain.
Radix Glycyrrhizae: nature and flavor are sweet, flat.In its sweet gentle slow and side the fever and chills and warm and cool various kinds of drug with, can be in harmonious proportion the bias of various medicines, all medicines and association can better be played a role.
Herba speranskiae tuberculatae: nature and flavor hardship, cold.Clearing away heat and cooling blood is arranged, the repercussive effect of bringing down a fever, control all rheumatalgia contractures of muscles and bones, traumatic injury, the disturbance of lower legs due to pathogenic cold and dampness etc.
Rhizoma Homalomenae: the bitter in the mouth suffering, warm in nature.The effect of wind-damp dispelling, bone and muscle strengthening is arranged, be adapted to anemofrigid-damp arthralgia, muscles and bones is unable, and disease such as spasm of the limbs, numbness, the effect of blood stasis dispelling is arranged.Be the robustness medicine for rheumatism.
Herba Lycopodii: the bitter in the mouth suffering, warm in nature.Xin Erhang looses, turbid, the temperature three-way meridian of bitter dampness, is applicable to diseases such as anemofrigid-damp arthralgia, skin numbness, extremities joint are ached, muscle arteries and veins joint stuffiness.Wind-expelling pain-stopping is arranged, the effect of collateral dredging Shujin.
The specific embodiment
Embodiment 1: Olibanum 12 grams, Myrrha 10 grams, Flos Carthami 10 grams, Rhizoma Zingiberis 10 grams, Radix Angelicae Pubescentis 10 grams, Fructus Zanthoxyli 10 grams, Sanguis Draxonis 5 grams, Herba Menthae 18 grams, Pericarpium Citri Reticulatae 10 grams, Radix Aconiti 15 grams, Radix Aconiti Kusnezoffii 15 grams, Radix Glycyrrhizae 10 grams, Rhizoma Homalomenae 10 grams, Herba speranskiae tuberculatae 10 grams, Herba Lycopodii 10 grams.
Embodiment 2: Olibanum 20 grams, Myrrha 20 grams, Flos Carthami 20 grams, Rhizoma Zingiberis 20 grams, Radix Angelicae Pubescentis 20 grams, Fructus Zanthoxyli 20 grams, Sanguis Draxonis 7 grams, Herba Menthae 10 grams, Pericarpium Citri Reticulatae 20 grams, Radix Aconiti 10 grams, Radix Aconiti Kusnezoffii 10 grams, Radix Glycyrrhizae 20 grams, Rhizoma Homalomenae 20 grams, Herba speranskiae tuberculatae 20 grams, Herba Lycopodii 20 grams.
Embodiment 3: Olibanum 15 grams, Myrrha 15 grams, Flos Carthami 15 grams, Rhizoma Zingiberis 15 grams, Radix Angelicae Pubescentis 15 grams, Fructus Zanthoxyli 15 grams, Sanguis Draxonis 10 grams, Herba Menthae 15 grams, Pericarpium Citri Reticulatae 15 grams, Radix Aconiti 20 grams, Radix Aconiti Kusnezoffii 20 grams, Radix Glycyrrhizae 15 grams, Rhizoma Homalomenae 15 grams, Herba speranskiae tuberculatae 15 grams, Herba Lycopodii 15 grams.
Above Chinese herbal medicine mix put add in the container the above Chinese liquor 500---1000 of 50 degree milliliter two to three weeks of dipping, get filter paper and leach medicinal liquid and promptly make Chinese medicine cutaneous permeable agent of the present invention.
Chinese medicine cutaneous permeable agent of the present invention is as being referred to as " the holographic therapy of 5 dimensions ", having remedied taking stopgap measures of traditional monotherapy and the defect of insufficient of effecting a permanent cure in conjunction with acupuncture and moxibustion treatment, HUOLONG therapy, transdermal administration therapy, scrape therapy, midnight-noon and ebb-flow doctrine therapy, systematic treating, pursuit are at all comprehensively.

Claims (2)

1, a kind of Chinese medicine cutaneous permeable agent, it is characterized in that: it is made by the raw material of following parts by weight: Olibanum 10-20 part, Myrrha 10-20 part, Flos Carthami 10-20 part, Rhizoma Zingiberis 10-20 part, Radix Angelicae Pubescentis 10-20 part, Fructus Zanthoxyli 10-20 part, Sanguis Draxonis 5-10 part, Pericarpium Citri Reticulatae 10-20 part, Herba Menthae 10-20 part, Radix Aconiti 10-20 part, Radix Aconiti Kusnezoffii 10-20 part, Radix Glycyrrhizae 10-20 part, Rhizoma Homalomenae 10-20 part, Herba speranskiae tuberculatae 10-20 part, Herba Lycopodii 10-20 part, the above Chinese liquor 500-1000 part of 50 degree.
2, a kind of Chinese medicine cutaneous permeable agent according to claim 1, it is characterized in that: it is made by the raw material of following parts by weight:
20 parts of Olibanums, 20 parts of Myrrhas, 20 parts on Flos Carthami, 20 parts of Rhizoma Zingiberiss, 20 parts of Radix Angelicae Pubescentiss, 20 parts of Fructus Zanthoxylis, 7 parts of Sanguis Draxonis, 20 parts of Pericarpium Citri Reticulataes, 10 parts of Herba Menthaes, 10 parts of Radix Aconitis, 10 parts of Radix Aconiti Kusnezoffii, 20 parts in Radix Glycyrrhizae, 20 parts of Rhizoma Homalomenaes, 20 parts of Herba speranskiae tuberculataes, 20 parts of Herba Lycopodiis, the above Chinese liquor 500-1000 part of 50 degree.
CNB200710011734XA 2007-06-12 2007-06-12 A kind of Chinese medicine cutaneous permeable agent Expired - Fee Related CN100571770C (en)

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Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102846456A (en) * 2012-09-28 2013-01-02 天津市百利康泰生物技术有限公司 Skin scraper with skin care liquid
CN103007229B (en) * 2012-12-27 2013-11-27 陈淑香 Medicine for treating neurogenic bladder
CN104547992A (en) * 2014-12-17 2015-04-29 徐鹏飞 Five-element channel-dredging powder
CN104758684A (en) * 2015-04-02 2015-07-08 柳培健 Traditional Chinese medicine compound for treating knee spasm by external application
CN106692560A (en) * 2015-07-23 2017-05-24 翟化军 Externally-applied traditional Chinese medicine liquid for treating osteoproliferation and preparation method thereof
CN105687900A (en) * 2016-02-26 2016-06-22 毕建飞 Traditional Chinese medicine composition for treating ankylosing spondylitis and preparation
CN106390072A (en) * 2016-11-16 2017-02-15 兰艳丽 Plaster for treating lumbar intervertebral disc protrusion
CN109663107A (en) * 2017-10-17 2019-04-23 云南苗心康生物科技有限公司 A kind of conditioning powder improving mammary gland disease
CN111956773A (en) * 2020-08-26 2020-11-20 周璇 Moxibustion stick and preparation method thereof
CN112316099A (en) * 2020-12-03 2021-02-05 邬丛兵 Traditional Chinese medicine transdermal agent and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
外用黑膏药的临床研究概况. 陈丽云.上海中医药杂志,第6期. 2002
外用黑膏药的临床研究概况. 陈丽云.上海中医药杂志,第6期. 2002 *

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