CN103893436B - A kind of externally applied drug for treating rheumatism - Google Patents
A kind of externally applied drug for treating rheumatism Download PDFInfo
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- CN103893436B CN103893436B CN201210579846.6A CN201210579846A CN103893436B CN 103893436 B CN103893436 B CN 103893436B CN 201210579846 A CN201210579846 A CN 201210579846A CN 103893436 B CN103893436 B CN 103893436B
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Abstract
The present invention relates to it is a kind of treat rheumatism, rheumatism externally applied drug, specifically a kind of external pulvis medicine with the effect such as warming channel and expelling cold, disperse blood stasis and dredge collateral, swelling and pain relieving and dehumidifying.The raw material that the medicine is matched by following parts by weight is made:7 parts of the bark of eucommia, 7 parts of the root of bidentate achyranthes, see within thousand 4 parts, 4 parts of peach kernel, 4 parts of safflower, 4 parts of drynaria baronii, 7 parts of datura flower, 1 part of aconiti preparata,radix, 4 parts of Radix Angelicae Sinensis, 2 parts of the root of Dahurain angelica；Preparation method is：The bark of eucommia, the root of bidentate achyranthes, thousand are seen, peach kernel, safflower, drynaria baronii, datura flower, aconiti preparata,radix, Radix Angelicae Sinensis, the taste medicinal material of the root of Dahurain angelica 10 pick only, dry and be ground into fine powder respectively, be mixed quantitative package, and every bag of 50g is standby；By honey and dose by 1 when using：After 1 proportioning, mixing batter shape, it is placed on 5cm × 5cm gauzes, is externally applied at patient's pain spot, then with infrared radiation, 30 minutes every time, once a day, per 10 days as one therapeutic course.Observation has therapeutic effect good in clinical drug of the present invention, and cure rate is high, the advantage of difficulty in relapse after healing.
Description
Technical field
The present invention relates to it is a kind of treat rheumatism, rheumatism externally applied drug, specifically it is a kind of have it is warming channel and expelling cold,
The external pulvis medicine of the effects such as disperse blood stasis and dredge collateral, swelling and pain relieving and dehumidifying.
Background technology
At present treatment rheumatism, rheumatoid medicine it is a lot, mostly oral medicine, treatment has certain effect, but due to rheumatism
The Case treatment cycle is long, easily forms DILD, nephrosis, stomach trouble.External used medicine of the present invention reduces oral dose, it is to avoid dirty
The damage of internal organs function, and external application Chinese medicine is different from other rheumatism plasters, deep to be accepted by many patients, simple and easy to apply, curative effect
Definitely, it is without any side effects.
The content of the invention
It is an object of the invention to provide a kind of externally applied drug for treating rheumatism, its feature：Analgesic is quick, have no adverse reaction,
Its analgesic effect is equivalent to antirheumatic nonsteroidal anti-inflammatory drug, the lesions of liver and kidney orally brought without nonsteroidal anti-inflammatory drug and digestion
The side reaction in road.
The object of the present invention is achieved like this, and the raw material that the medicine is matched by following parts by weight is made:The bark of eucommia 7
Part, 7 parts of the root of bidentate achyranthes, see within thousand 4 parts, 4 parts of peach kernel, 4 parts of safflower, 4 parts of drynaria baronii, 7 parts of datura flower, 1 part of aconiti preparata,radix, 4 parts of Radix Angelicae Sinensis, the root of Dahurain angelica
2 parts；
Preparation method is：The bark of eucommia, the root of bidentate achyranthes, thousand are seen, peach kernel, safflower, drynaria baronii, datura flower, aconiti preparata,radix, Radix Angelicae Sinensis, the root of Dahurain angelica
10 taste medicinal materials pick only, dry and be ground into fine powder respectively, be mixed quantitative package, and every bag of 50g is standby；By honey and dose by 1 when using：
After 1 proportioning, mixing batter shape, it is placed on 5cm × 5cm gauzes, is externally applied at patient's pain spot, then uses infrared radiation（It is roasting）, every time
30 minutes, once a day, per 10 days as one therapeutic course.
The present invention has the advantages that：
1st, the present invention is according to the theory of the traditional Chinese medical science " no pain by smooth breath, not general rule pain ", set up warming and activating meridian, evacuate pathogenic wind dispelling cold and removing dampness,
Stopping numbness pain.Wherein using datura flower, aconiti preparata,radix as monarch drug in a prescription, share and both Radix Aconiti can also be suppressed with quickly alleviating pain, datura flower
Toxicity, the bark of eucommia, the root of bidentate achyranthes, see within thousand, drynaria baronii, with filling liver kidney, strengthening the bones and muscles, wind-damp dispelling, stopping numbness pain, be ministerial drug, peach kernel, safflower,
Radix Angelicae Sinensis has the qi and blood of logical whole body, and stagnation resolvation is just to make medicine without hindering；The pungent-warm of the root of Dahurain angelica is helped, in awakening consciousness priming enters.All medicine phases
With playing filling liver kidney, strengthening the bones and muscles, wind-damp dispelling, stopping numbness pain, effect promoting blood circulation and removing blood stasis altogether.
2nd, medicine of the present invention is externally applied drug, is different from rheumatic plaster traditional in the market, and modern medicine rheumatism
Patch, spray, liniment etc..It is that the prepared slices of Chinese crude drugs process powder, the quantitative every bag of 50g of packaging through technique.It is for rheumatism, class wind
Each arthroncus caused by wet wind-cold damp pathogen, ache, it is stiff, bend and stretch difficulty, chilly, cold, foul wind and have certain curative effect.
3rd, clinical trail observation of the medicine of the present invention by 2 years 90 rheumatoid patients, theoretical validation, with quickly disappearing
Swollen analgesic, relief of symptoms.The quality of life of patient can be changed, delay or prevent anchylosis from deforming, instant effect, nontoxic secondary work
With.It is suitable for the treatment and popularization of rheumatism, rheumatoid arthritis.
The clinical observation material of medicine of the present invention
1st, rheumatoid clinical case is selected
Totally 90, treatment group 50, control group 40.Treatment group man 10, female 40；It is -66 years old age 18, average
43.2 years old.The course of disease 1 years 6 months, it is average 6.1 years.Control group man 10, female 30；It is 18 1 64 years old age, average 42.8 years old.
The course of disease 1 years 6 months, it is average 5.9 years.Two groups there was no significant difference, P<0.05.
What rheumatoid arthrosis diagnostic criteria was edited with reference to Shanghai Medical Univ《Practical clinical practice》:1. morning stiffness 1 hour>6 weeks；
2. the arthroncus of more than 3) 6 weeks；3. type joint swelling or proximal interphalangeal joints swelling) 6 weeks；4. symmetry arthroncus) 6
Week；5. subcutaneous nodule；) X pieces display bone erosion；7. rheumatoid factor positive.Possess in the above 74 it is i.e. diagnosable.Symptom:
Pain of joint muscle is fixed, sore spot tenderness, local swelling, scleroma or purple plague purpura, limitation of activity, thin white fur of tongue or thin Huang, veins string.
Exclusion standard：Gestation or women breast-feeding their children, articular skin has damaged person, to externally applied drug powder or capsaicin cream
Allergy sufferers, infectional arthritis, serious Liver and kidney function lesion person.
2nd, verification method
The treatment group 50 exception present invention, usage and dosage, external application, one to two bags every time, every bag with 50g -100g honey,
After mixing batter shape, 5cm × 5cm gauzes are placed on, affected part is spread on, 2-3 millimeters of thickness is then infrared with TDP with covered rearing with plastic film
Line is baked, and removes warm water washing affected part after 30 minutes every time.Once a day, it is weekly a course for the treatment of.Leflunomide every time 2 is taken simultaneously
Piece, day is once oral, and pain severe patient takes Meloxicam 2, and day is once.
Control group 40 uses capsaicin cream（Produced by Changchun 999 Bio-Pharmaceutical Co., Ltd）, according to its involvement
Joint size takes uniform outer is applied to outside arthralgia surface of appropriate book layer to apply RA joint parts, and TDP irradiates affected part after preheating,
40 DEG C of skin surface temperature is kept to be advisable, irradiation time is 30 min/ time, once a day, every 10 be a course for the treatment of, while taking
Fluorine rice is special, and 2 tablets once, and day is once oral, and pain severe patient takes Meloxicam 2, and day is once.
Therapentic part：Unified selection refers to, the treatment of wrist, SCID Mice, once a day.Clinical efficacy is sentenced after 10 days
It is fixed.
3rd, observation index
(1), general physical examination project
(2), blood urine routine test
4th, health giving quality is observed
(1) local symptom such as joint, skin, muscles and bones, such as pain, numbness, cool, it is stiff, miserable, swell
The symptom situation of change such as swollen.
(2) erythrocyte sedimentation rate, c reactive protein.
5th, criterion of therapeutical effect
It is effective:Cardinal symptom, sign entirety improvement rate 75%, erythrocyte sedimentation rate and CRP often or are obviously improved or close to normal;It is progressive:
The overall improvement rate 50% of cardinal symptom, sign, erythrocyte sedimentation rate and CRP have improvement;Effectively:The overall improvement rate 30% of cardinal symptom, sign, blood
Heavy and CRP has improvement or without improvement；It is invalid:The overall improvement rate 30% of cardinal symptom, sign, erythrocyte sedimentation rate and CRP are without improvement.
6th, treatment results
Effective 10 for the treatment of group, progressive 30, effective 7, invalid 3, the .% of total effective rate 94;Control group effective 7, enters
Step 12, effective 11, invalid 10, total effective rate 75%.
Two groups are compared that there were significant differences.Treatment group takes effect 3 one 4 days, average 6.2 days；Control group takes effect 5-9 days.Treatment group
Toxic side effect is not found;There is glutamic-pyruvic transaminase rise in control group 1, is disappeared after drug withdrawal.
Obvious treatment group is better than control group, illustrates that this patent externally applied drug has certain effect to treatment rheumatism.
Embodiment
Bulk drug bark of eucommia 7kg, root of bidentate achyranthes 7kg are weighed by proportioning, see within thousand 4kg, greater celandine 4kg, match leaf 4kg, drynaria baronii 4
Kg, the kg of datura flower 7, the kg of aconiti preparata,radix 1, the kg of Radix Angelicae Sinensis 4, the kg of the root of Dahurain angelica 2, above-mentioned all bulk drugs are dried, 40 mesh are crossed after crushing
Sieve, be mixed quantitative package, every bag of 50g.
Application method：The invention belongs to external application Chinese medicine, honey presses 1 with dose：1 proportioning, adjusts uniform into pasty state, the used time is placed on
5cm × 5cm gauzes, are placed at patient's pain spot.Then infrared radiation is used（It is roasting）, 30 minutes every time, per 10 days as one therapeutic course.Skin
Skin allergy sufferers should be discontinued.Or add desensitizer.
Claims (1)
1. a kind of externally applied drug for treating rheumatism, it is characterised in that：The raw material that the medicine is matched by following parts by weight is made:
7 parts of the bark of eucommia, 7 parts of the root of bidentate achyranthes, see within thousand 4 parts, 4 parts of peach kernel, 4 parts of safflower, 4 parts of drynaria baronii, 7 parts of datura flower, 1 part of aconiti preparata,radix, Radix Angelicae Sinensis 4
Part, 2 parts of the root of Dahurain angelica；
Preparation method is：The bark of eucommia, the root of bidentate achyranthes, thousand are seen, peach kernel, safflower, drynaria baronii, datura flower, aconiti preparata,radix, Radix Angelicae Sinensis, the taste of the root of Dahurain angelica 10
Medicinal material pick only, dry and be ground into fine powder respectively, be mixed quantitative package, and every bag of 50g is standby.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210579846.6A CN103893436B (en) | 2012-12-28 | 2012-12-28 | A kind of externally applied drug for treating rheumatism |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210579846.6A CN103893436B (en) | 2012-12-28 | 2012-12-28 | A kind of externally applied drug for treating rheumatism |
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| Publication Number | Publication Date |
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| CN103893436A CN103893436A (en) | 2014-07-02 |
| CN103893436B true CN103893436B (en) | 2017-09-12 |
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| CN201210579846.6A Active CN103893436B (en) | 2012-12-28 | 2012-12-28 | A kind of externally applied drug for treating rheumatism |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104352957A (en) * | 2014-10-21 | 2015-02-18 | 李时业 | Ancient and modern comprehensive physical therapy |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1481853A (en) * | 2002-09-12 | 2004-03-17 | 郭志忠 | Food-cure medicated wine which can cure bone arthralgia and preparation method |
| CN101461871A (en) * | 2008-12-26 | 2009-06-24 | 方召云 | Medicinal liquor for treating arthritis and lumbocrural pain, and preparation method thereof |
| CN101480433A (en) * | 2008-01-09 | 2009-07-15 | 张刘森 | Health plaster for rheumatism |
| CN102038761A (en) * | 2010-12-21 | 2011-05-04 | 韩少晖 | Medicament for treating rheumatoid diseases |
-
2012
- 2012-12-28 CN CN201210579846.6A patent/CN103893436B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1481853A (en) * | 2002-09-12 | 2004-03-17 | 郭志忠 | Food-cure medicated wine which can cure bone arthralgia and preparation method |
| CN101480433A (en) * | 2008-01-09 | 2009-07-15 | 张刘森 | Health plaster for rheumatism |
| CN101461871A (en) * | 2008-12-26 | 2009-06-24 | 方召云 | Medicinal liquor for treating arthritis and lumbocrural pain, and preparation method thereof |
| CN102038761A (en) * | 2010-12-21 | 2011-05-04 | 韩少晖 | Medicament for treating rheumatoid diseases |
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| CN103893436A (en) | 2014-07-02 |
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