CN101703720A - Chinese medicinal preparation for treating cough - Google Patents

Chinese medicinal preparation for treating cough Download PDF

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Publication number
CN101703720A
CN101703720A CN200810103690A CN200810103690A CN101703720A CN 101703720 A CN101703720 A CN 101703720A CN 200810103690 A CN200810103690 A CN 200810103690A CN 200810103690 A CN200810103690 A CN 200810103690A CN 101703720 A CN101703720 A CN 101703720A
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China
Prior art keywords
cough
lung
radix
chinese medicine
chinese medicinal
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CN200810103690A
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Chinese (zh)
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刘星梅
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BEIJING WANSHOUTONG PHARMACEUTICAL TECHNOLOGY CORP
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BEIJING WANSHOUTONG PHARMACEUTICAL TECHNOLOGY CORP
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Priority to CN200810103690A priority Critical patent/CN101703720A/en
Publication of CN101703720A publication Critical patent/CN101703720A/en
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Abstract

The invention relates to Chinese medicinal preparation for treating cough, which uses more than 10 Chinese medicinal herbs as raw materials, such as ephedra herb, almond, fineleaf schizonepeta herb, sessile stemona root and the like. The preparation has the functions of expelling wind and cold pathogens, and releasing lungs to relieve cough. The Chinese medicinal preparation is developed by combining latest modern scientific achievements with traditional treatment by differentiation of symptoms and signs. The invention aims to provide the Chinese medicinal preparation for treating the cough, which has the characteristics of definite curative effect, safety and convenience, no toxic or side effect and low price.

Description

A kind of Chinese medicine preparation for the treatment of cough
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of cough, is that a kind of to treat cough be the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Cough is one of main syndrome of lung pattern disease, and how because of the objective lung of heresy system, impaired depurative descending of lung QI due to lung qi is unclear, is a cardinal symptom with cough, expectoration.Be more common in acute and chronic bronchitis.The major lesions of cough is at lung, and is but closely related with liver,spleen,kidney.Its pathogenesis has diseases caused by exogenous pathogenic factor, internal injury two big classes, and the exogenous cough is six climate exopathogens exopathogen invasion and attack lung system, and the endogenous cough has disorder of emotion, improper diet and the dificiency of the lung due to protracted disease, always because of visceral dysfunction, and the dried lung of interior heresy.No matter evil from outside go into, or, all can cause impaired depurative descending of lung QI from interior and send out, abnormal rising of lung-QI is coughed.When dialectical, first when difference diseases caused by exogenous pathogenic factor and internal injury, treatment should divide clear pathogen weakened body resistance reality.The exogenous cough belongs to the domination of pathogen, controls when eliminating evil sharp lung.The endogenous cough, to belong to the domination of pathogen weakened body resistance more, controls when eliminating evil cough-relieving, sets upright tonify deficiency, and giving consideration to both the incidental and fundamental is distinguished the deficiency and excess primary and secondary and is handled.The traditional Chinese medical science divides syndrome of wind-cold attacking lung, syndrome of wind-heat invading lung, pathogenic dryness impairing the lung card, syndrome of phlegm-heat obstructing lung, syndrome of liver fire invading lung, phlegm-damp to accumulate that lung card, lung yin lose deficiency syndrome, lung qi loses disease type Coryza Treated by Syndrome Differentiation such as deficiency syndrome, obtains very good effect clinically.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of cough.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
0.1~2 part of 0.1~2 part of Fructus Perillae of 1.0~4 parts of Semen Armeniacae Amarums of Folium Eriobotryae
0.1~2 part of 0.1~2 part of Exocarpium Citri Grandis of 0.1~2 portion of Herba Schizonepetae of Cortex Mori
0.1~2 part of 0.1~2 part of Semen Raphani of 0.1~2 part of Radix Peucedani of Rhizoma Cynanchi Stauntonii
0.1~1 part in 0.1~2 portion of Herba Ephedrae of 0.1~2 part of Radix Platycodonis of the Radix Stemonae.
The weight proportion of each crude drug of optimization formula of the present invention is:
0.5~1.5 part of 0.5~1.5 part of Fructus Perillae of 1.5~2.5 parts of Semen Armeniacae Amarums of Folium Eriobotryae
0.5~1.5 part of 0.5~1.5 part of Exocarpium Citri Grandis of 0.5~1.5 portion of Herba Schizonepetae of Cortex Mori
0.5~1.5 part of 0.5~1.5 part of Semen Raphani of 0.5~1.5 part of Radix Peucedani of Rhizoma Cynanchi Stauntonii
0.3~0.7 part in 0.5~1.5 portion of Herba Ephedrae of 0.5~1.5 part of Radix Platycodonis of the Radix Stemonae.
The weight proportion of each crude drug of optimum formula of the present invention is:
1 part of 1 part of Fructus Perillae of 2 parts of Semen Armeniacae Amarums of Folium Eriobotryae
1 part of 1 part of Exocarpium Citri Grandis of 1 portion of Herba Schizonepetae of Cortex Mori
1 part of 1 part of Semen Raphani of 1 part of Radix Peucedani of Rhizoma Cynanchi Stauntonii
0.5 part in 1 portion of Herba Ephedrae of 1 part of Radix Platycodonis of the Radix Stemonae.
Drug action mechanism among the present invention is as follows:
Folium Eriobotryae nature and flavor hardship, be slightly cold. attach to the lung and stomach meridians. have clearing away lung-heat to relieve cough, the effect of stopping nausea and vomiting by lowering the adverse flow of QI. can treat the cough due to lung-heat, the QI rising in reverse order dyspnea with rapid respiration, the gastric heat vomiting, dysphoria with smothery sensation is thirsty etc. and (the 163rd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Cortex Mori nature and flavor are sweet, hot, and are cold.Return lung, spleen channel.Has eliminating pathogen from the lung for relieving asthma, the effect of inducing diuresis to remove edema.Cure mainly the fullness in the chest that lung-heat or diseases caused by retention of fluid stop lung and breath with cough hemoptysis, edema, beriberi, dysuria etc.(the 2787th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Cynanchi Stauntonii property of medicine suffering, sweet, tepor.Return lung meridian.Has the eliminating the pathogens from the lung sending down the abnormal ascending QI, the effect of expelling phlegm for arresting cough.Lung qi be can treat and the cough with copious phlegm of reality, dyspnea due to adverseness of QI, gastralgia, infantile malnutrition, traumatic injury etc. stopped up.(the 961st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Stemonae property of medicine hardship, little sweet, tepor.Return lung meridian.Has nourishing the lung to arrest cough, the effect of parasite killing delousing.Can treat new chronic cough and cough, pulmonary tuberculosis, pertussis, enterobiasis, body louse, tinea scabies etc.(the 1179th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Armeniacae Amarum property of medicine hardship, tepor, mild toxicity.Return lung, large intestine channel.Has lowering the adverse-rising QI to resolve phlegm, relieving cough and asthma, the effect of loosening bowel to relieve constipation.Can treat exogenous cough's dyspnea with fullness of the chest, dryness of the intestine constipation etc.(the 1526th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Schizonepetae property of medicine suffering, little hardship, tepor.Return lung, Liver Channel.Have and dispel the wind, induce sweat, rash, hemostatic effect.Can treat cold, fever, headache, eye itching, cough, laryngopharynx swelling and pain, measles, rubella, carbuncle, the skin ulcer scabies, epistaxis is spitted blood, and has blood in stool metrorrhagia, puerperal blood faints etc.(the 2112nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Peucedani property of medicine hardship, suffering are slightly cold.Return lung, spleen, Liver Channel.Has dispelling wind and heat pathogens, the effect of lowering the adverse-rising QI to resolve phlegm.Can treat affection due to external wind and heat, the lung-heat phlegm stagnancy, the cough with asthma abundant expectoration, expectorant is yellow thick glutinous, the vomiting lack of appetite, chest and diaphragm is completely vexed etc.(the 2411st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Platycodonis property of medicine hardship, suffering, flat.Attach to the lung and stomach meridians.Have lung qi dispersing and eliminate the phlegm, the effect of sore-throat relieving evacuation of pus.Can treat cough with copious phlegm, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache, uroschesis etc.(the 2528th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Perillae nature and flavor suffering, temperature.Return lung meridian.Have the sending down the abnormal ascending QI expectorant, relieving asthma, the effect of intestine moistening.Expectorant be can treat and QI rising in reverse order, cough and asthma, dryness of the intestine constipation etc. stopped up.(the 279th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Exocarpium Citri Grandis property of medicine hardship, suffering, temperature.Return lung, spleen channel.Have drying dampness to eliminate phlegm, regulate the flow of vital energy, the effect that helps digestion.Can treat wind and cold cough with asthma abundant expectoration, vomiting singultus, accumulation of food in the stomach and intes tine due to indigestion, abdominal distention etc.(the 636th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Raphani property of medicine suffering, sweet, flat.Return spleen, stomach, lung, large intestine channel.Has dyspepsia and intestinal stasis relieving, the effect of lowering the adverse-rising QI to resolve phlegm.Can treat stagnation of QI due to dyspepsia, distension and fullness in the abdomen, diarrhoea, heavy behind the dysentery, cough ant phlegm, QI rising in reverse order dyspnea with fullness of the chest etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Ephedrae property of medicine suffering, little hardship, temperature.Return lung, urinary bladder channel.Has relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, the effect of inducing diuresis to remove edema.Can treat chill exterior syndrome, cough and asthma, edema due to wind pathogen, dysuria, rheumatic arthralgia, numbness of the skin, rubella pruritus, carbuncle of yin nature sucutaneous nodule etc.(the 3094th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Herba Ephedrae, Semen Armeniacae Amarum and Cortex Mori; With Herba Schizonepetae, the Radix Stemonae, Rhizoma Cynanchi Stauntonii, Folium Eriobotryae, Radix Peucedani and Fructus Perillae is ministerial drug; With Radix Platycodonis, Exocarpium Citri Grandis and Semen Raphani is adjuvant. and all medicines are harmonious, and are total to the tool expelling wind and cold, the effect of lung qi dispersing cough-relieving. and the treatment cough has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment cough of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat cough, and the prevention of coughing is also had good effect, and the treatment cough has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment cough; Treatment cough patient 47 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.34 examples of fully recovering account for 72.34%, and 9 examples that take a turn for the better account for 19.15%, and more 4 examples do not account for 8.5%, and total effective rate reaches 91.5%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 decoction is pressed following weight weighting raw materials:
1 part of 1 part of Fructus Perillae of 2 parts of Semen Armeniacae Amarums of Folium Eriobotryae
1 part of 1 part of Exocarpium Citri Grandis of 1 portion of Herba Schizonepetae of Cortex Mori
1 part of 1 part of Semen Raphani of 1 part of Radix Peucedani of Rhizoma Cynanchi Stauntonii
0.5 part in 1 portion of Herba Ephedrae of 1 part of Radix Platycodonis of the Radix Stemonae.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of treatment that the present invention makes cough is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Embodiment 2 capsules are pressed following weight weighting raw materials:
1 part of 1 part of Fructus Perillae of 2 parts of Semen Armeniacae Amarums of Folium Eriobotryae
1 part of 1 part of Exocarpium Citri Grandis of 1 portion of Herba Schizonepetae of Cortex Mori
1 part of 1 part of Semen Raphani of 1 part of Radix Peucedani of Rhizoma Cynanchi Stauntonii
0.5 part in 1 portion of Herba Ephedrae of 1 part of Radix Platycodonis of the Radix Stemonae.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, decoct with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree~55 are spent, be concentrated into the clear paste of relative density 1.30~1.32, drying, be ground into fine powder, incapsulate.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2~10, two to three times on the one, three months is a course of treatment.

Claims (3)

1. Chinese medicine preparation for the treatment of cough is characterized in that it is made by following raw materials by weight proportions:
0.1~2 part of 0.1~2 part of Fructus Perillae of 1.0~4 parts of Semen Armeniacae Amarums of Folium Eriobotryae
0.1~2 part of 0.1~2 part of Exocarpium Citri Grandis of 0.1~2 portion of Herba Schizonepetae of Cortex Mori
0.1~2 part of 0.1~2 part of Semen Raphani of 0.1~2 part of Radix Peucedani of Rhizoma Cynanchi Stauntonii
0.1~1 part in 0.1~2 portion of Herba Ephedrae of 0.1~2 part of Radix Platycodonis of the Radix Stemonae.
2. a kind of Chinese medicine preparation for the treatment of cough according to claim 1, wherein the weight proportion of each crude drug is:
0.5~1.5 part of 0.5~1.5 part of Fructus Perillae of 1.5~2.5 parts of Semen Armeniacae Amarums of Folium Eriobotryae
0.5~1.5 part of 0.5~1.5 part of Exocarpium Citri Grandis of 0.5~1.5 portion of Herba Schizonepetae of Cortex Mori
0.5~1.5 part of 0.5~1.5 part of Semen Raphani of 0.5~1.5 part of Radix Peucedani of Rhizoma Cynanchi Stauntonii
0.3~0.7 part in 0.5~1.5 portion of Herba Ephedrae of 0.5~1.5 part of Radix Platycodonis of the Radix Stemonae.
3. a kind of Chinese medicine preparation for the treatment of cough according to claim 1, wherein the weight proportion of each crude drug is:
1 part of 1 part of Fructus Perillae of 2 parts of Semen Armeniacae Amarums of Folium Eriobotryae
1 part of 1 part of Exocarpium Citri Grandis of 1 portion of Herba Schizonepetae of Cortex Mori
1 part of 1 part of Semen Raphani of 1 part of Radix Peucedani of Rhizoma Cynanchi Stauntonii
0.5 part in 1 portion of Herba Ephedrae of 1 part of Radix Platycodonis of the Radix Stemonae.
CN200810103690A 2008-04-10 2008-04-10 Chinese medicinal preparation for treating cough Pending CN101703720A (en)

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CN200810103690A CN101703720A (en) 2008-04-10 2008-04-10 Chinese medicinal preparation for treating cough

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CN101703720A true CN101703720A (en) 2010-05-12

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102580037A (en) * 2012-03-15 2012-07-18 广东省中医院 Chinese medicinal composition for treating cough caused by cold-type infection and preparation method thereof
CN104687194A (en) * 2015-02-28 2015-06-10 广西大学 Heat-clearing, phlegm-dissipating and cough-relieving beverage and preparation method thereof
CN104984036A (en) * 2015-08-11 2015-10-21 薛振宇 Traditional Chinese medicine composition treating asthma coughs

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102580037A (en) * 2012-03-15 2012-07-18 广东省中医院 Chinese medicinal composition for treating cough caused by cold-type infection and preparation method thereof
CN104687194A (en) * 2015-02-28 2015-06-10 广西大学 Heat-clearing, phlegm-dissipating and cough-relieving beverage and preparation method thereof
CN104984036A (en) * 2015-08-11 2015-10-21 薛振宇 Traditional Chinese medicine composition treating asthma coughs
CN104984036B (en) * 2015-08-11 2018-08-24 薛振宇 A kind of Chinese medicine composition for treating asthma and cough

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Open date: 20100512