CN100415289C - A Chinese traditional medicinal preparation for treatment of leukoderma - Google Patents

A Chinese traditional medicinal preparation for treatment of leukoderma Download PDF

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CN100415289C
CN100415289C CNB2006101139483A CN200610113948A CN100415289C CN 100415289 C CN100415289 C CN 100415289C CN B2006101139483 A CNB2006101139483 A CN B2006101139483A CN 200610113948 A CN200610113948 A CN 200610113948A CN 100415289 C CN100415289 C CN 100415289C
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radix
parched
semen
salt
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CN1943767A (en
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王信锁
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Abstract

A kind of Chinese medicine preparation, made from radix bupleuri, radix curcumae , semen astragali complanati, semen cuscutae, rhizoma drynariae, fructus tribuli, radix saposhnikoviae, rhizoma atractylodis macrocephalae, radix paeoniae alba, poria, semen persicae, flos carthami, semen raphani, pericarpium citri reticulatae. The invention can nourish liver and kidney, lead liver, eliminate gloomy, active blood, eliminate stasis, moisten skin, and eliminate white spot, with precise curative effect to the treatment and prevention of vitiligo, without toxic and side effects, easy to take and with low prices.

Description

The leukodermic Chinese medicine preparation of a kind of treatment
Technical field
The present invention relates to the leukodermic Chinese medicine preparation of a kind of treatment, is that a kind of vitiligo for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Vitiligo is a kind of posteriority limitation depigmentation dermatosis.Go down with skin color, bleach, boundary distinctness, no conscious sympton are feature.The same with other pigment anomalies, leukodermic sickness rate is with area, the ethnic group colour of skin and different.The dark more people's sickness rate of general colour is high more, and prevalence is about 0.1~2% in the population of China.The men and women can fall ill until old every year from the newborn baby about equally, but is many with teenager, has data to show that age of onset is in the majority 10~30 years old group, accounts for 62.65% of sum, and women's age of onset was than male about 5 years ahead of time.
Leukodermic clinical manifestation is: the skin at any position all can take place, but good sending out in being subject to solar radiation and frictionally damage position, as facial area, cervical region, trunk and extremity etc.The inboard mucosa of lip, labia, glans penis and foreskin also can involve.Most of leukasmus is symmetrically distributed, also has part patient white macula to distribute along nerve segment.Skin lesion is a limitation depigmentation speckle, milky, from fingernail to the coin size, circular, ellipse or irregular type.White macula place hair also can bleach.In progressive stage, the decolouring speckle is divided a word with a hyphen at the end of a line to normal skin, and development is very fast, and isomorphic response is arranged, and promptly can form the secondary vitiligo after pressure, friction, the wound.
Can divide three types according to leukoderma scope and distribution: 1, the topical type skin lesion is confined to a position, can be divided into 1. segmental pattern again: skin lesion is pressed dermatomere and is distributed; 2. mucosa type: only involve mucosa.2, general hair style is the most common, shows as skin lesion and is distributed widely in body surface, can be divided into 1. homeliness type: skin lesion is dispersed in and is distributed in the body surface many places; 2. face acra type: skin lesion is distributed in face and far-end of limb; 3. mixed type: above-mentioned several various combinations form.As face acra type+segmental pattern etc.3, whole body type, whole skin all decolour fully or almost, also have hair to bleach.
Primary disease is equivalent to leucoderma, the vitiligo of the traditional Chinese medical science.Put down in writing as " General Treatise on the Cause and Symptoms of Diseases " leucoderma: " the leucoderma person, face and neck health skin and flesh complexion changed are white, and be different with meat, the pain of also not itching, the leucoderma of meaning." and for example " the Yizong Jinjian surgery heart shows " vitiligo record: " vitiligo is the face collar humorously, and the ailment said due to cold or exposure white point speckle even all over of fighting does not mutually have the pain of itching, and controls and should fully recover from an illness by the pathogenic wind expelling fat liquoring.”
The traditional Chinese medical science thinks that leukodermic morbidity is outer because experience ailment said due to cold or exposure, injury from falling down; Interior because of feelings will internal injury, hemorrhagic disorder and consumption of essence etc., these can make qi-blood disharmony, and obstruction of collaterals by blood stasis, deficiency of the liver and kindey lead to this disease.So the treatment of the traditional Chinese medical science is to be divided into disease types such as disharmony between QI and blood, retention of damp-heat in the interior, obstruction of collaterals by blood stasis, deficiency of the liver and kindey, stagnation of QI due to depression of the liver to carry out Coryza Treated by Syndrome Differentiation.The leukodermic method of western medical treatment is a lot, but great majority can only reach recent clinical effectiveness, and can not prevent recurrence, and has toxic and side effects in various degree.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the leukodermic Chinese medicine preparation of a kind of treatment, have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
2.5~10 parts of 1.5~6 parts of salt Semen Astragali Complanatis of 1.5~6 portions of Radix Curcumaes of Radix Bupleuri (processed with vinegar)
2.5~10 parts of 1.5~6 parts of salt Semen Cuscutae of 1.5~6 parts of Radix Saposhnikoviaes of stir-baked FRUCTUS TRIBULI
2.5~10 parts of 1.5~6 parts of Rhizoma drynariae preparatas of 1.5~6 parts of Poria of Radix Paeoniae Alba
1~4 part of 1~4 part of Semen Raphani (parched) of 1.5~6 parts of Flos Carthamis of Rhizoma Atractylodis Macrocephalae (parched)
1~4 part of 1~4 part of Pericarpium Citri Reticulatae of Semen Persicae (parched)
The weight proportion of each raw material of optimization formula of the present invention is:
3~7 parts of 2.5~3.5 parts of salt Semen Astragali Complanatis of 2.5~3.5 portions of Radix Curcumaes of Radix Bupleuri (processed with vinegar)
3~7 parts of 2.5~3.5 parts of salt Semen Cuscutae of 2.5~3.5 parts of Radix Saposhnikoviaes of stir-baked FRUCTUS TRIBULI
3~7 parts of 2.5~3.5 parts of Rhizoma drynariae preparatas of 2.5~3.5 parts of Poria of Radix Paeoniae Alba
1.5~2.5 parts of 1.5~2.5 parts of Semen Raphani (parched) of 2.5~3.5 parts of Flos Carthamis of Rhizoma Atractylodis Macrocephalae (parched)
1.5~2.5 parts of 1.5~2.5 parts of Pericarpium Citri Reticulataes of Semen Persicae (parched)
The weight proportion of each raw material of optimum formula of the present invention is:
5 parts of 3 parts of salt Semen Astragali Complanatis of 3 portions of Radix Curcumaes of Radix Bupleuri (processed with vinegar)
5 parts of 3 parts of salt Semen Cuscutae of 3 parts of Radix Saposhnikoviaes of stir-baked FRUCTUS TRIBULI
5 parts of 3 parts of Rhizoma drynariae preparatas of 3 parts of Poria of Radix Paeoniae Alba
2 parts of 2 parts of Semen Raphani (parched) of 3 parts of Flos Carthamis of Rhizoma Atractylodis Macrocephalae (parched)
2 parts of 2 parts of Pericarpium Citri Reticulataes of Semen Persicae (parched)
Drug action mechanism among the present invention is as follows:
Radix Bupleuri (processed with vinegar) nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Have reconciling superficies and interior, soothing the liver, the effect of yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
Radix Curcumae nature and flavor suffering, hardship, cold.GUIXIN, lung, Liver Channel.Effect with promoting QI circulation for relieving depression, removing heat from blood removing blood stasis with potent drugs, promoting the function of the gallbladder to alleviate jaundice, the relieving restlessness that clears away heart-fire.Can treat hepatocarcinoma, carcinoma of gallbladder, carcinoma of head of pancreas, all pains of breast abdomen side of body rib, lose that the heart is demented, calentura coma, haematemesis, epistaxis, hematuria, women's example warp, jaundice, arteriosclerosis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 794th page).
Salt Semen Astragali Complanati nature and flavor are sweet, temperature.Return liver, kidney channel.Has the temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs, reducing urination, the effect that makes eye bright.Can treat lumbago due to renal deficiency, seminal emission premature ejaculation, nebulousurine leukorrhagia, dribbling urination, dizzy blurred vision etc.(the 145th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Salt Semen Cuscutae nature and flavor suffering, sweet, warm, flat.Return the liver,kidney,spleen warp.Have invigorating the liver and kidney, beneficial marrow, the smart effect of the benefit that makes eye bright.Can treat gastric cancer, osteocarcinoma, pulmonary carcinoma, nasopharyngeal carcinoma, soreness of waist and knee joint, impotence and seminal emission, quench one's thirst, dripping urination, order are dark, Light-headedness, visual deterioration, frequent fetal movement, frequent micturition etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1066th page).
Rhizoma drynariae preparata nature and flavor hardship, temperature.Return kidney, Liver Channel.Have the kidney invigorating bone strengthening, continuous hinder pain relieving, invigorate blood circulation, the hemostatic effect.Can treat osteocarcinoma, osteosarcoma, the chronic diarrhea of suffering from a deficiency of the kidney, lumbago, rheumatic arthralgia, Hiccough and deaf, odontoseisis, fall wink frustrate, muscles and bones wound, appendicitis, alopecia areata, clavus, vitiligo, congestion are had a pain, rheumatic arthritis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 930th page).
Stir-baked FRUCTUS TRIBULI nature and flavor suffering, hardship, tepor; Slightly poisonous.Return Liver Channel.Have the suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind makes eye bright, the itching relieving effect.It is dizzy to treat headache, distending pain in the chest and hypochondrium, and breast closes acute mastitis, conjunctival congestion cataracta, rubella pruritus etc.(the 289th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Radix Saposhnikoviae nature and flavor suffering, sweet, temperature.Return bladder, liver, spleen channel.Have inducing diaphoresis to dispel wind, win and wet, the effect of relieving convulsion.Can treat headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus etc.(the 117th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Rhizoma Atractylodis Macrocephalae (parched) nature and flavor hardship, sweet, warm.Return spleen, stomach warp.Have invigorating the spleen and replenishing QI, the dampness diuresis and in antiabortive, strengthening superficial resistance to stop perspiration, anticancer effect.Can treat that pulmonary carcinoma, gastric cancer, cervical cancer, insufficiency of the spleen lack of appetite, abdominal distention are had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement, asthma, phlegmatic cough, leucorrhea, nebulousurine, seminal emission, gonorrhea, frequent micturition etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 447th page).
Radix Paeoniae Alba nature and flavor hardship, acid, be slightly cold.Return liver, spleen channel.Effect with suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating, antibiotic, thrombocytosis.Can treat that the pain over the hypochondriac region, dysentery stomachache, night sweat, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia, headache are dizzy, limb pain twin, blood deficiency and yellow complexion etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 432nd page).
The Poria nature and flavor are sweet, flat, light.GUIXIN, lung, spleen, kidney channel.Has eliminating dampness and diuresis, the effect of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Can treat that dysuria, edema distension, phlegm retention cough with dyspnea, brain are throbbed with fear, have loose bowels in the loose stool, irritability, palpitation with fear, insomnia, forgetful, seminal emission, stranguria with turbid discharge, insufficiency of the spleen, stop that drink is not eaten, gastral cavity is vexed, three YIN malaria (malaria pathogen in three YIN) disease, heating do not heal, end empty YANG-depletion etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 898th page).
Semen Persicae (parched) nature and flavor hardship, sweet, flat.GUIXIN, liver, large intestine channel.Has blood stasis removing and clots absorbing, the effect of loosening bowel to relieve constipation.Can control amenorrhea, dysmenorrhea, mass in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 986th page).
Flos Carthami nature and flavor suffering, temperature.GUIXIN, Liver Channel.Effect with promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Can treat that amenorrhea, lump in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, traumatic injury etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 604th page).
Semen Raphani (parched) acrid-sweet flavor, flat, cool.Return spleen, stomach, lung meridian.Have removing food stagnancy stagnate, reduce phlegm heat, therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, antidotal effect.Can treat food stagnation distension, phlegmatic cough aphonia, haematemesis, epistaxis, quench one's thirst, dysentery and migraine and general headache etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 993rd page).
Pericarpium Citri Reticulatae nature and flavor hardship, suffering, temperature.Return lung, spleen channel.Has regulating qi-flowing for strengthening spleen, the effect of drying dampness to eliminate phlegm.Can treat fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm etc.(the 149th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", with Radix Bupleuri (processed with vinegar), Radix Curcumae, salt Semen Astragali Complanati, salt Semen Cuscutae, Semen Persicae (parched) and Flos Carthami is monarch drug, Rhizoma drynariae preparata, stir-baked FRUCTUS TRIBULI, Radix Saposhnikoviae, Rhizoma Atractylodis Macrocephalae (parched), Radix Paeoniae Alba and Poria are ministerial drug, and Semen Raphani (parched) and Pericarpium Citri Reticulatae are adjuvant.All medicines have the effect of nourishing the liver and kidney, dispersing the stagnated live-QI to relieve the stagnation of QI, promoting blood circulation by removing wind, the white and moist skin that disappears mutually and altogether, treatment and prevention vitiligo, and determined curative effect has no side effect, and taking convenience is cheap.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, buccal tablet granule, electuary, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.Preparation of the present invention, peroral dosage form preferably, as: tablet, capsule, oral liquid, buccal tablet, granule, electuary, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment and the prevention vitiligo of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid, also contain various trace elements such as Saponin, plant sterol and calcium, be beneficial to absorption of human body, health invigorating, and taking convenience.
3, the present invention not only can effectively treat vitiligo, and leukodermic prevention is also had good effect, has improved patient's life quality greatly, and higher healing rehabilitation efficacy is arranged.
Further specify medicine of the present invention to treatment therapy for vitiligo effect below by the clinical practice example.
Vitiligo curative effect determinate standard (the 228th page of Chen Qin chief editor " research and development of Chinese medicine cosmetic health product " Chinese Medicine science and technology publishing house version in 1999.)
(1) recovery from illness: the white macula complete obiteration, histopathology of skin checks normal.
(2) produce effects: white macula disappears more than 50%, and white macula disappearance portion of tissue pathological examination is normal.
(3) effective: white macula disappearance person accounts for 20%~50% of former white macula area, or sees have than the polychrom island in white macula.
(4) invalid: no change or white macula enlarge before and after the treatment.
As follows through clinical test results; Treatment patients with vitiligo 62 examples, male's 26 examples, women's 36 examples, the age is 10~46 years old.Take embodiment 1 capsule, each 2-10 grain, every day three to four times, eliminating cold for resuscitation water send down, and take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.50 examples of fully recovering account for 80.6%, and produce effects 6 examples account for 9.7%, and effective 4 examples account for 6.4%, and invalid 2 examples account for 3.2%, and total effective rate reaches more than 96%.After three course of therapy, the patient skin white macula disappears in various degree or fully recovers.And patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 capsule takes by weighing raw material by following weight:
5 parts of 3 parts of salt Semen Astragali Complanatis of 3 portions of Radix Curcumaes of Radix Bupleuri (processed with vinegar)
5 parts of 3 parts of salt Semen Cuscutae of 3 parts of Radix Saposhnikoviaes of stir-baked FRUCTUS TRIBULI
5 parts of 3 parts of Rhizoma drynariae preparatas of 3 parts of Poria of Radix Paeoniae Alba
2 parts of 2 parts of Semen Raphani (parched) of 3 parts of Flos Carthamis of Rhizoma Atractylodis Macrocephalae (parched)
2 parts of 2 parts of Pericarpium Citri Reticulataes of Semen Persicae (parched)
Preparation method is to get Radix Bupleuri (processed with vinegar), Radix Curcumae, the salt Semen Astragali Complanati, the salt Semen Cuscutae, Rhizoma drynariae preparata, stir-baked FRUCTUS TRIBULI, Radix Saposhnikoviae, Rhizoma Atractylodis Macrocephalae (parched), Radix Paeoniae Alba, Poria, Semen Persicae (parched), Flos Carthami, Semen Raphani (parched) and Pericarpium Citri Reticulatae decoct with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree~55 are concentrated into the clear paste of relative density 1.30~1.32, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2~10, three to four times on the one, two months is a course of treatment.
Embodiment 2 tablets take by weighing raw material by following weight:
5 parts of 3 parts of salt Semen Astragali Complanatis of 3 portions of Radix Curcumaes of Radix Bupleuri (processed with vinegar)
5 parts of 3 parts of salt Semen Cuscutae of 3 parts of Radix Saposhnikoviaes of stir-baked FRUCTUS TRIBULI
5 parts of 3 parts of Rhizoma drynariae preparatas of 3 parts of Poria of Radix Paeoniae Alba
2 parts of 2 parts of Semen Raphani (parched) of 3 parts of Flos Carthamis of Rhizoma Atractylodis Macrocephalae (parched)
2 parts of 2 parts of Pericarpium Citri Reticulataes of Semen Persicae (parched)
Preparation method is to get Radix Bupleuri (processed with vinegar) earlier, Radix Curcumae, the salt Semen Astragali Complanati, the salt Semen Cuscutae, Rhizoma drynariae preparata, stir-baked FRUCTUS TRIBULI, Radix Saposhnikoviae, Rhizoma Atractylodis Macrocephalae (parched), Radix Paeoniae Alba, Poria, Semen Persicae (parched), Flos Carthami, Semen Raphani (parched) and Pericarpium Citri Reticulatae decoct with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree~55 are concentrated into the clear paste of relative density 1.30~1.32, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2~10, three to four times on the one, two months is a course of treatment.
Embodiment 3 granules take by weighing raw material by following weight:
5 parts of 3 parts of salt Semen Astragali Complanatis of 3 portions of Radix Curcumaes of Radix Bupleuri (processed with vinegar)
5 parts of 3 parts of salt Semen Cuscutae of 3 parts of Radix Saposhnikoviaes of stir-baked FRUCTUS TRIBULI
5 parts of 3 parts of Rhizoma drynariae preparatas of 3 parts of Poria of Radix Paeoniae Alba
2 parts of 2 parts of Semen Raphani (parched) of 3 parts of Flos Carthamis of Rhizoma Atractylodis Macrocephalae (parched)
2 parts of 2 parts of Pericarpium Citri Reticulataes of Semen Persicae (parched)
Preparation method is to get Radix Bupleuri (processed with vinegar), Radix Curcumae, the salt Semen Astragali Complanati, the salt Semen Cuscutae, Rhizoma drynariae preparata, stir-baked FRUCTUS TRIBULI, Radix Saposhnikoviae, Rhizoma Atractylodis Macrocephalae (parched), Radix Paeoniae Alba, Poria, Semen Persicae (parched), Flos Carthami, Semen Raphani (parched) and Pericarpium Citri Reticulatae decoct with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, and the clear paste of relative density 1.08~1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree~55 are spent, be concentrated into the clear paste of relative density 1.30~1.32, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1~3 bag, three to four times on the one, two months is a course of treatment.

Claims (3)

1. leukodermic Chinese medicine preparation of treatment is characterized in that it is made by following raw materials by weight proportions:
2.5~10 parts of 1.5~6 parts of salt Semen Astragali Complanatis of 1.5~6 portions of Radix Curcumaes of Radix Bupleuri (processed with vinegar)
2.5~10 parts of 1.5~6 parts of salt Semen Cuscutae of 1.5~6 parts of Radix Saposhnikoviaes of stir-baked FRUCTUS TRIBULI
2.5~10 parts of 1.5~6 parts of Rhizoma drynariae preparatas of 1.5~6 parts of Poria of Radix Paeoniae Alba
1~4 part of 1~4 part of Semen Raphani (parched) of 1.5~6 parts of Flos Carthamis of Rhizoma Atractylodis Macrocephalae (parched)
1~4 part of 1~4 part of Pericarpium Citri Reticulatae of Semen Persicae (parched).
2. the leukodermic Chinese medicine preparation of a kind of treatment according to claim 1, wherein the weight proportion of each crude drug is:
3~7 parts of 2.5~3.5 parts of salt Semen Astragali Complanatis of 2.5~3.5 portions of Radix Curcumaes of Radix Bupleuri (processed with vinegar)
3~7 parts of 2.5~3.5 parts of salt Semen Cuscutae of 2.5~3.5 parts of Radix Saposhnikoviaes of stir-baked FRUCTUS TRIBULI
3~7 parts of 2.5~3.5 parts of Rhizoma drynariae preparatas of 2.5~3.5 parts of Poria of Radix Paeoniae Alba
1.5~2.5 parts of 1.5~2.5 parts of Semen Raphani (parched) of 2.5~3.5 parts of Flos Carthamis of Rhizoma Atractylodis Macrocephalae (parched)
1.5~2.5 parts of 1.5~2.5 parts of Pericarpium Citri Reticulataes of Semen Persicae (parched).
3. the leukodermic Chinese medicine preparation of a kind of treatment according to claim 1, wherein the weight proportion of each crude drug is:
5 parts of 3 parts of salt Semen Astragali Complanatis of 3 portions of Radix Curcumaes of Radix Bupleuri (processed with vinegar)
5 parts of 3 parts of salt Semen Cuscutae of 3 parts of Radix Saposhnikoviaes of stir-baked FRUCTUS TRIBULI
5 parts of 3 parts of Rhizoma drynariae preparatas of 3 parts of Poria of Radix Paeoniae Alba
2 parts of 2 parts of Semen Raphani (parched) of 3 parts of Flos Carthamis of Rhizoma Atractylodis Macrocephalae (parched)
2 parts of 2 parts of Pericarpium Citri Reticulataes of Semen Persicae (parched).
CNB2006101139483A 2006-10-23 2006-10-23 A Chinese traditional medicinal preparation for treatment of leukoderma Expired - Fee Related CN100415289C (en)

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Application Number Priority Date Filing Date Title
CNB2006101139483A CN100415289C (en) 2006-10-23 2006-10-23 A Chinese traditional medicinal preparation for treatment of leukoderma

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CN100415289C true CN100415289C (en) 2008-09-03

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CN103989738A (en) * 2014-05-18 2014-08-20 洛阳市安普生物科技有限公司 Formula of antibacterial liquid for treating leucoderma and sweat white spot

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Title
中药外用治疗白癜风的临床应用概况. 陈梅花,许爱娥.中国中西医结合皮肤性病学杂志,第4卷第4期. 2005
中药外用治疗白癜风的临床应用概况. 陈梅花,许爱娥.中国中西医结合皮肤性病学杂志,第4卷第4期. 2005 *

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