CN1943745A - A Chinese traditional medicinal preparation for treatment of urticaria - Google Patents
A Chinese traditional medicinal preparation for treatment of urticaria Download PDFInfo
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Abstract
This invention relates to a kind of traditional Chinese medicine product, which can be used in therapy of the urticaria. It is made up of some raw materials including Rhizoma Smilacis Glabrae, Flos Campsis, Radix astragali, Cortex Dictamni , Fructus Tribuli, Periostracum Cicadae, Radix Saposhnikoviae, Radix et Rhizoma Salviae Miltiorrhizae, Herba Schizonepetae, Radix angelicae sinensis, Radix Paeoniae Alba, Radix astragali, Scolopendra, Radix Stemonae and Nidus Vespae. The Chinese medicine product in this invention has the efficacies of heat-clearing and blood-cooling, exterior-resolving and yin-enriching, wind-coursing and itching-relieving, toxin-resolving and petechia-discharging. The product can be used in preventing and curing the urticaria. It is characterized in its definite curative effect, no toxic side effective, taking-convenient and inexpensive price.
Description
Technical field
The present invention relates to the urticarial Chinese medicine preparation of a kind of treatment, is that a kind of urticaria for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Urticaria is owing to skin, the little vascular reactivity expansion of mucosa and permeability increase a kind of localized edema reaction that produces.Primary disease is more common, and the people of about 15%-25% was taken place once in life at least.The urticaria traditional Chinese medical science is called urticaria, rubella, red rash, miliaria alba, acute angioneurotic edema, urticaria etc.Be commonly called as terrible wind pimple, rubella wheal, bellows chamber etc.As saying that " the evil exopathogenic heat of husband is skin, meets wind and cold and hinders and then play urticaria, and overabundant heat is red complexion then, and wind color at most is white, and very the person itches bitterly, and that scratches then becomes skin ulcer in " Standards of Diagnosis and Treatment air door "." " urticaria person, the sound granule is had a nightmare among skin, the loathing of cold pruritus all over of generating heat and for example " surgery great achievement urticaria ".Classical prescription: exposure to the wind after sweating due to overstrain, Nai Cuo Rush.The little red complexion of heat, heat is darkish complexion very., control and should lung heat clearing fall expectorant and induce sweat at lung by expectorant heat.”
The urticaria clinical manifestation is the localized edema welt that differs in size.The welt color can be cerise, pale red, pale asphyxia or skin-color, and form can rounded, oval, annular or irregular shape.Welt can take place suddenly in several minutes, can disappear in several minutes to a few hours, did not stay any vestige, but this plays that again, outbreak repeatedly.Its Clinical symptoms is stepped back no vestige for taking place rapidly and disappearing, and itches with play.Severe patient can be with headache, dizziness, arthralgia, stomachache, nausea,vomiting,diarrhea, uncomfortable in chest, nervous, hoarseness, dyspnea, severe patient can occur that laryngeal edema, pale complexion, heart rate quicken, anaphylactic shock such as pulse is thin and delicate, blood pressure drops, confusion, threat to life.Clinical in course of disease length, generally anxious onset, the course of disease was called acute urticaria at three months with interior person, and its morbidity is hurried, the welt number is more, how with General Symptoms; Welt shows effect repeatedly and is called chronic urticaria above person more than three months, and is few for a long time during its welt, but most welt is less, and General Symptoms is lighter.
The common cause of disease of urticaria has: 1. food: as fish, shrimp, Eriocheir sinensis, egg or milk etc.2. medicine: penicillin, furazolidone, serum, vaccine etc.3. infect: tonsillitis, viral hepatitis, Enterozoa etc.4. animal and plant factor: as sucking scurf, feather or the pollen etc. of animal.5. physics and chemical factor: as hot and cold, daylight, friction and pressure etc.6. internal organs and general disease and nervously all can bring out primary disease.
Urticaria also has specific type urticaria, (1) peptone urticaria (acute protein anaphylaxis urticaria) except that being divided into acute urticaria and chronic urticaria.(2) cold urticaria is divided into again: familial cold urticaria and acquired cold urticaria.(3) heat urticaria.(4) cholinergic urticaria.(5) solar urticaria.(6) pressure urticaria.(7) aquagenic urticaria.(8) serum sickness urticaria.(9) autoimmunity Progesterone urticaria.(10) angioedema (huge urticaria).(11) factitial urticaria.
Acute urticaria disappeared through a few days or several weeks, and reason is more easily traced, and disappeared rapidly after dispeling the cause of disease.Chronic urticaria is shown effect repeatedly, does not heal throughout the year.Cause of disease complexity is difficult to find out, lives, brings mentally very big misery and inconvenience to the patient.Serious symptom when its acute attack can cause the shock of suffocating, threat to life.Therefore, the problem of relevant prevention minimizing chronic urticaria recurrence is the difficult point of present clinical treatment aspect.
The Chinese traditional treatment acute urticaria is single can to obtain good curative effect with treatment by Chinese herbs.Clinical syndrome differentiation is based on excess syndrome, heat syndrome, and common card has pattern of syndrome such as wind heat, blood hot air wind producing, the intestines and stomach be damp and hot, and ailment said due to cold or exposure is a main external cause, treats antipruritic based on dispelling wind; Be equipped with the medicine of relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, clearing away heat and cooling blood, heat clearing away purging FU-organs intestinal stasis relieving respectively.The chronic urticaria Chinese medical discrimination is many with deficiency syndrome, blood stasis syndrome.Common pattern of syndrome has: insufficiency of the spleen catching cold, weakened defensive QI; Deficiency of qi and blood; Give birth in the hepatic and renal YIN deficiency, wind syndrome caused by deficiency; Qi depression to blood stasis; Chong and Ren channel disorder etc.Treat respectively with invigorating the spleen and benefiting QI the cold expelling consolidating superficial resistance; Benefiting QI and nourishing blood, dispelling wind is antipruritic; Adjusting and reinforcing liver and kidney, nourishing blood to stop wind syndrome; Blood circulation promoting and blood stasis dispelling, dispelling wind for relieving itching; Regulating thoroughfare and controlling vessel is a method.
Doctor trained in Western medicine thinks that urticaria will prevent its recurrence, at first when finding clear and definite its cause of disease, is removed.But often the cause of disease is difficult to find clinically.So present western medical treatment is symptomatic treatment mostly.Traditional antihistaminic has stronger maincenter inhibition ability easily to produce the drowsiness side effect that waits, and the antihistaminic of a new generation does not have side effect such as drowsiness as astemizole, loratadine, cetirizine etc., and its short term effect is better, but late result is relatively poor.This is concerning treatment of Chronic Urticaria and reduce its relapse rate, and curative effect is often not ideal enough.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the urticarial Chinese medicine preparation of a kind of treatment, and have determined curative effect, safe ready, little, the cheap characteristics of side effect.
The present invention is made by the following weight proportion raw material:
1.5～6 parts of 1～4 part of Radix Astragali of 2.5～10 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
1.5～6 parts of 1.5～6 parts of Radix Paeoniae Alba of 1.5～6 parts of Radix Saposhnikoviaes of Flos Campsis
1.5～6 parts of 1～4 part of Radix Angelicae Sinensis (processed with wine) of 2.5～10 parts of Radix Sophorae Flavescentiss of Radix Rehmanniae
0.1～2 part in 1.5～6 parts of Nidus Vespae of 2.5～10 portions of Herba Schizonepetae of Cortex Dictamni
0.1～1 part of 1～4 part of Scolopendra of 1.5～6 parts of Radixs Stemonae of stir-baked FRUCTUS TRIBULI
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～6 parts of 1.5～2.5 parts of Radix Astragali of 3～7 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
1.5～6 parts of 2～4 parts of Radix Paeoniae Alba of 2～4 parts of Radix Saposhnikoviaes of Flos Campsis
2～4 parts of 1.5～2.5 parts of Radix Angelicae Sinensis (processed with wine) of 3～7 parts of Radix Sophorae Flavescentiss of Radix Rehmanniae
0.5～1.5 part in 2～4 parts of Nidus Vespae of 3～7 portions of Herba Schizonepetae of Cortex Dictamni
0.3～0.7 part of 1.5～2.5 parts of Scolopendra of 2～4 parts of Radixs Stemonae of stir-baked FRUCTUS TRIBULI
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 2 parts of Radix Astragali of 5 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
3 parts of 3 parts of Radix Paeoniae Alba of 3 parts of Radix Saposhnikoviaes of Flos Campsis
3 parts of 2 parts of Radix Angelicae Sinensis (processed with wine) of 5 parts of Radix Sophorae Flavescentiss of Radix Rehmanniae
1 part in 3 parts of Nidus Vespae of 5 portions of Herba Schizonepetae of Cortex Dictamni
0.5 part of 2 parts of Scolopendra of 3 parts of Radixs Stemonae of stir-baked FRUCTUS TRIBULI
Drug action mechanism among the present invention is as follows:
The Rhizoma Smilacis Glabrae nature and flavor are sweet, light, flat.Return liver, stomach warp.Has heat-clearing and toxic substances removing, wind-damp dispelling, bone and muscle strengthening, sharp joint, anticancer effect.Can treat damp and hot sore, eczema, rheumatic ostalgia, limbs contracture, Fructus Myricae rubrae malignant boil, urinary system infection, syphilis, stranguria with turbid discharge, stranguria leucorrhea, dyspepsia, diarrhoea, beriberi, furuncle, carbuncle, scrofula etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 87th page).
The Flos Campsis nature and flavor are sweet, sour, and are cold.Return liver, pericardium channel.Has removing heat from blood, blood stasis dispelling, the effect of dispeling the wind.Can treat menoxenia, amenorrhea and mass in the abdomen, puerperal swelling of the breast, rubella is rubescent, skin pruritus, acne etc.(the 236th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Cortex Dictamni nature and flavor hardship, cold.Return spleen, stomach, urinary bladder channel.Has heat clearing and damp drying, the antidotal effect of dispeling the wind.Can treat damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, rheumatism pyretic arthralgia, jaundice dark coloured urine etc.(the 83rd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Stir-baked FRUCTUS TRIBULI nature and flavor suffering, hardship, tepor; Slightly poisonous.Return Liver Channel.Have the suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind makes eye bright, the itching relieving effect.It is dizzy to treat headache, distending pain in the chest and hypochondrium, and breast closes acute mastitis, conjunctival congestion cataracta, rubella pruritus etc.(the 289th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Periostracum Cicadae nature and flavor are sweet, salty, cold.Return lung, Liver Channel.Has diffusing wind heat extraction, sore-throat relieving, rash, nebula removing, the effect of spasmolytic.Can treat anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, tetanus etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1254th page).
Radix Saposhnikoviae nature and flavor suffering, sweet, temperature.Return bladder, liver, spleen channel.Have inducing diaphoresis to dispel wind, win and wet, the effect of relieving convulsion.Can treat headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus etc.(the 117th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Radix Sophorae Flavescentis nature and flavor hardship, cold.Return liver, kidney, large intestine, small intestine meridian.Have heat clearing away, dampness, parasite killing, anticancer effect.Can treat toxic-heat and blood stasis, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, leprosy, infantile pneumonia, infantile malnutrition, acute tonsillitis, anal fistula, acute enteritis, bacillary dysentery, amebic dysentery, external treatment trichomonal vaginitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 779th page).
Herba Schizonepetae nature and flavor suffering, temperature.Return lung, Liver Channel.Have the diffusing wind that induces sweat, rash is antipruritic, treating blood disorders hemostasis, the clear sharp head, analgesic effect.Can treat flu, headache, measles, rubella, skin infection from the beginning of etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 876th page).
The Radix Angelicae Sinensis (processed with wine) nature and flavor are sweet, hot, warm.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation.Can be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea stimulates the menstrual flow, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 553rd page).
Radix Paeoniae Alba nature and flavor hardship, acid, be slightly cold.Return liver, spleen channel.Effect with suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating, antibiotic, thrombocytosis.Can treat that the pain over the hypochondriac region, dysentery stomachache, night sweat, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia, headache are dizzy, limb pain twin, blood deficiency and yellow complexion etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 432nd page).
The Radix Astragali nature and flavor are sweet, warm.Return lung, spleen channel.Have benefit and defend consolidating superficial resistance, inducing diuresis to remove edema, poison holding, the effect of granulation promoting.What be used for that internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, metrorrhagia and leukorrhagia, spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle do not burst or burst does not hold back and the disease of all weakness of QI blood deficiency.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1074th page).
Scolopendra nature and flavor suffering, temperature, poisonous.Return Liver Channel.Effect with endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Can treat that infantile convulsion, tic spasm, middle air port are askew, hemiplegia, tetanus disease, rheumatoid arthritis stubborn, skin infection, scrofula, venom etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1238th page).
Radix Stemonae nature and flavor are sweet, bitter, tepor.Return lung meridian.Has nourishing the lung to keep the adverse QI downward cough-relieving, parasiticidal effect.Can treat new chronic cough and cough, pulmonary tuberculosis cough, pertussis; Be used for head louse outward, body louse, enterobiasis, pudendal pruritus.Honey Radix Stemonae nourishing the lung to arrest cough.Be used for deficiency of YIN chronic cough etc.(the 100th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Nidus Vespae nature and flavor are sweet, and are flat.Return the stomach warp.Have and dispel the wind, counteracting toxic substances, parasite killing, analgesic effect.Can treat toothache due to dental caries, sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, fungal infection of hand and foot etc.(the 294th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", with Rhizoma Smilacis Glabrae, Flos Campsis, Radix Rehmanniae and Cortex Dictamni is monarch drug, with stir-baked FRUCTUS TRIBULI, Radix Saposhnikoviae, Radix Sophorae Flavescentis, Herba Schizonepetae, Radix Angelicae Sinensis (processed with wine), Radix Paeoniae Alba, Radix Astragali, the Scolopendra Radix Stemonae and Nidus Vespae is ministerial drug, is adjuvant with Periostracum Cicadae.All medicine phases and the effect that is total to tool clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, counteracting toxic substances dissipating blood stasis, dispelling wind for relieving itching, the treatment urticaria has determined curative effect, has no side effect taking convenience, cheap characteristics.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, buccal tablet, granule, electuary, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.Preparation of the present invention, preferred Chinese medicine preparation is a peroral dosage form, as: tablet, capsule, oral liquid, buccal tablet, granule, electuary, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment and the prevention urticaria of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid, also contain various trace elements such as Saponin, plant sterol and calcium, be beneficial to absorption of human body, health invigorating, and taking convenience.
3, the present invention not only can effectively treat urticaria, and urticarial prevention is also had good effect, has improved patient's life quality greatly, and higher healing rehabilitation efficacy is arranged.
Further specify medicine of the present invention to treating urticarial therapeutic effect below by the clinical practice example.
The urticaria curative effect determinate standard: 1. cure: welt disappears, and clinical sign disappears, and the person does not reaccess.2. take a turn for the better:
Welt disappear 30% or the back recurrent interval time that disappears prolong sx persons such as pruritus.3. do not heal: welt and pruritus do not have obvious improver, or the less than 30% that disappears.(the 859th page of chief editor's " traditional Chinese medical science disease diagnosis and treatment standard and prescription are selected for use " People's Health Publisher's calendar year 2001 version such as Dai Shen).
As follows through clinical test results; Treatment urticaria patient 39 examples, male's 20 examples, women's 19 examples, the age is 18～60 years old.Take embodiment 1 capsule, each 2-10 grain, every day three to four times, eliminating cold for resuscitation water send down, and take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.31 examples of fully recovering account for 79.5%, and 5 examples that take a turn for the better account for 12.82%, and more 3 examples do not account for 7.69%, and total effective rate reaches 92.31%.After three course of therapy, symptoms such as patient's welt and pruritus all have clear improvement or fully recover.And patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 capsule takes by weighing raw material by following weight:
3 parts of 2 parts of Radix Astragali of 5 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
3 parts of 3 parts of Radix Paeoniae Alba of 3 parts of Radix Saposhnikoviaes of Flos Campsis
3 parts of 2 parts of Radix Angelicae Sinensis (processed with wine) of 5 parts of Radix Sophorae Flavescentiss of Radix Rehmanniae
1 part in 3 parts of Nidus Vespae of 5 portions of Herba Schizonepetae of Cortex Dictamni
0.5 part of 2 parts of Scolopendra of 3 parts of Radixs Stemonae of stir-baked FRUCTUS TRIBULI
Preparation method is to get Periostracum Cicadae earlier, Scolopendra and Nidus Vespae drying and crushing to 120～200 order fine powders, Poria again fetches earth, Flos Campsis, Radix Rehmanniae, Cortex Dictamni, stir-baked FRUCTUS TRIBULI, Radix Saposhnikoviae, Radix Sophorae Flavescentis, Herba Schizonepetae, Radix Angelicae Sinensis (processed with wine), Radix Paeoniae Alba, the Radix Astragali and the Radix Stemonae decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and Periostracum Cicadae, Scolopendra and Nidus Vespae fine powder mixing, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, two months is a course of treatment.
Embodiment 2 tablets take by weighing raw material by following weight:
3 parts of 2 parts of Radix Astragali of 5 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
3 parts of 3 parts of Radix Paeoniae Alba of 3 parts of Radix Saposhnikoviaes of Flos Campsis
3 parts of 2 parts of Radix Angelicae Sinensis (processed with wine) of 5 parts of Radix Sophorae Flavescentiss of Radix Rehmanniae
1 part in 3 parts of Nidus Vespae of 5 portions of Herba Schizonepetae of Cortex Dictamni
0.5 part of 2 parts of Scolopendra of 3 parts of Radixs Stemonae of stir-baked FRUCTUS TRIBULI
Preparation method is to get Periostracum Cicadae earlier, Scolopendra and Nidus Vespae drying and crushing to 120～200 order fine powders, Poria again fetches earth, Flos Campsis, Radix Rehmanniae, Cortex Dictamni, stir-baked FRUCTUS TRIBULI, Radix Saposhnikoviae, Radix Sophorae Flavescentis, Herba Schizonepetae, Radix Angelicae Sinensis (processed with wine), Radix Paeoniae Alba, the Radix Astragali and the Radix Stemonae decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and Periostracum Cicadae, Scolopendra and Nidus Vespae fine powder mixing, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, two months is a course of treatment.
Embodiment 3 granules take by weighing raw material by following weight:
3 parts of 2 parts of Radix Astragali of 5 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
3 parts of 3 parts of Radix Paeoniae Alba of 3 parts of Radix Saposhnikoviaes of Flos Campsis
3 parts of 2 parts of Radix Angelicae Sinensis (processed with wine) of 5 parts of Radix Sophorae Flavescentiss of Radix Rehmanniae
1 part in 3 parts of Nidus Vespae of 5 portions of Herba Schizonepetae of Cortex Dictamni
0.5 part of 2 parts of Scolopendra of 3 parts of Radixs Stemonae of stir-baked FRUCTUS TRIBULI
Preparation method is to get Periostracum Cicadae earlier, Scolopendra and Nidus Vespae drying and crushing to 120～200 order fine powders, Poria again fetches earth, Flos Campsis, Radix Rehmanniae, Cortex Dictamni, stir-baked FRUCTUS TRIBULI, Radix Saposhnikoviae, Radix Sophorae Flavescentis, Herba Schizonepetae, Radix Angelicae Sinensis (processed with wine), Radix Paeoniae Alba, the Radix Astragali and the Radix Stemonae decoct with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and Periostracum Cicadae, Scolopendra and Nidus Vespae fine powder mixing, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1～3 bag, three to four times on the one, two months is a course of treatment.
Claims (6)
1, the urticarial Chinese medicine preparation of a kind of treatment is characterized in that it is made by the following weight proportion raw material:
1.5～6 parts of 1～4 part of Radix Astragali of 2.5～10 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
1.5～6 parts of 1.5～6 parts of Radix Paeoniae Alba of 1.5～6 parts of Radix Saposhnikoviaes of Flos Campsis
1.5～6 parts of 1～4 part of Radix Angelicae Sinensis (processed with wine) of 2.5～10 parts of Radix Sophorae Flavescentiss of Radix Rehmanniae
0.1～2 part in 1.5～6 parts of Nidus Vespae of 2.5～10 portions of Herba Schizonepetae of Cortex Dictamni
0.1～1 part of 1～4 part of Scolopendra of 1.5～6 parts of Radixs Stemonae of stir-baked FRUCTUS TRIBULI
2, the urticarial Chinese medicine preparation of a kind of treatment according to claim 1, wherein the weight proportion of each raw material is:
1.5～6 parts of 1.5～2.5 parts of Radix Astragali of 3～7 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
1.5～6 parts of 2～4 parts of Radix Paeoniae Alba of 2～4 parts of Radix Saposhnikoviaes of Flos Campsis
2～4 parts of 1.5～2.5 parts of Radix Angelicae Sinensis (processed with wine) of 3～7 parts of Radix Sophorae Flavescentiss of Radix Rehmanniae
0.5～1.5 part in 2～4 parts of Nidus Vespae of 3～7 portions of Herba Schizonepetae of Cortex Dictamni
0.3～0.7 part of 1.5～2.5 parts of Scolopendra of 2～4 parts of Radixs Stemonae of stir-baked FRUCTUS TRIBULI
3, the urticarial Chinese medicine preparation of a kind of treatment according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 2 parts of Radix Astragali of 5 portions of Periostracum Cicadaes of Rhizoma Smilacis Glabrae
3 parts of 3 parts of Radix Paeoniae Alba of 3 parts of Radix Saposhnikoviaes of Flos Campsis
3 parts of 2 parts of Radix Angelicae Sinensis (processed with wine) of 5 parts of Radix Sophorae Flavescentiss of Radix Rehmanniae
1 part in 3 parts of Nidus Vespae of 5 portions of Herba Schizonepetae of Cortex Dictamni
0.5 part of 2 parts of Scolopendra of 3 parts of Radixs Stemonae of stir-baked FRUCTUS TRIBULI
4, the Chinese medicine preparation of claim 1-3 is to be fit to medicinal various dosage forms.
5, the Chinese medicine preparation of claim 4 is tablet, capsule, oral liquid, buccal tablet, granule, electuary, pill, powder, suspensoid, powder, solution, drop, drop pill.
6, the Chinese medicine preparation of claim 4 is capsule, tablet, granule.
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2006101139534A CN100415280C (en) | 2006-10-23 | 2006-10-23 | A Chinese traditional medicinal preparation for treatment of urticaria |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2006101139534A CN100415280C (en) | 2006-10-23 | 2006-10-23 | A Chinese traditional medicinal preparation for treatment of urticaria |
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| CN1943745A true CN1943745A (en) | 2007-04-11 |
| CN100415280C CN100415280C (en) | 2008-09-03 |
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| CNB2006101139534A Expired - Fee Related CN100415280C (en) | 2006-10-23 | 2006-10-23 | A Chinese traditional medicinal preparation for treatment of urticaria |
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| CN (1) | CN100415280C (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101628057B (en) * | 2009-08-14 | 2011-04-13 | 南宁市维威制药有限公司 | Pharmaceutical composition for treating senile skin pruritus and preparation method thereof |
| CN103566256A (en) * | 2013-10-25 | 2014-02-12 | 安徽工贸职业技术学院 | Traditional Chinese medicine composition for treating urticaria |
| CN103599329A (en) * | 2013-10-25 | 2014-02-26 | 安徽工贸职业技术学院 | Externally-used traditional Chinese medicinal pulvis for treating allergic skin diseases |
| CN103690844A (en) * | 2013-11-28 | 2014-04-02 | 祝迈 | External traditional Chinese medicine for treating urticaria |
| CN103908606A (en) * | 2014-04-04 | 2014-07-09 | 青岛市城阳区人民医院 | Traditional Chinese medicine ointment for treating urticaria |
| CN103908605A (en) * | 2014-04-04 | 2014-07-09 | 青岛大学医学院附属医院 | Traditional Chinese medicine preparation for treating urticaria |
| CN104474074A (en) * | 2014-11-18 | 2015-04-01 | 龚富先 | Traditional Chinese medicine external plaster used for treating itchy skin eruption and stuck to navel and preparation method of plaster |
| CN105054487A (en) * | 2015-08-11 | 2015-11-18 | 南阳师范学院 | Traditional Chinese medicine healthcare insole and preparation method thereof |
| CN109771507A (en) * | 2017-11-15 | 2019-05-21 | 广西西林县农本生物科技有限公司 | It is a kind of to treat dermopathic Chinese medicine composition |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2734309C (en) * | 2008-09-11 | 2015-11-10 | Qingdao Qiyuan Bio-Technologies Co., Ltd. | Preparation and usage of a pharmaceutical composition containing ferulic acid and matrine compounds |
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- 2006-10-23 CN CNB2006101139534A patent/CN100415280C/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101628057B (en) * | 2009-08-14 | 2011-04-13 | 南宁市维威制药有限公司 | Pharmaceutical composition for treating senile skin pruritus and preparation method thereof |
| CN103566256A (en) * | 2013-10-25 | 2014-02-12 | 安徽工贸职业技术学院 | Traditional Chinese medicine composition for treating urticaria |
| CN103599329A (en) * | 2013-10-25 | 2014-02-26 | 安徽工贸职业技术学院 | Externally-used traditional Chinese medicinal pulvis for treating allergic skin diseases |
| CN103690844A (en) * | 2013-11-28 | 2014-04-02 | 祝迈 | External traditional Chinese medicine for treating urticaria |
| CN103908606A (en) * | 2014-04-04 | 2014-07-09 | 青岛市城阳区人民医院 | Traditional Chinese medicine ointment for treating urticaria |
| CN103908605A (en) * | 2014-04-04 | 2014-07-09 | 青岛大学医学院附属医院 | Traditional Chinese medicine preparation for treating urticaria |
| CN104474074A (en) * | 2014-11-18 | 2015-04-01 | 龚富先 | Traditional Chinese medicine external plaster used for treating itchy skin eruption and stuck to navel and preparation method of plaster |
| CN105054487A (en) * | 2015-08-11 | 2015-11-18 | 南阳师范学院 | Traditional Chinese medicine healthcare insole and preparation method thereof |
| CN109771507A (en) * | 2017-11-15 | 2019-05-21 | 广西西林县农本生物科技有限公司 | It is a kind of to treat dermopathic Chinese medicine composition |
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| Publication number | Publication date |
|---|---|
| CN100415280C (en) | 2008-09-03 |
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