CN102389465B - Traditional Chinese medicine composition for treating gastropathy and its preparation method - Google Patents
Traditional Chinese medicine composition for treating gastropathy and its preparation method Download PDFInfo
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- CN102389465B CN102389465B CN 201110370167 CN201110370167A CN102389465B CN 102389465 B CN102389465 B CN 102389465B CN 201110370167 CN201110370167 CN 201110370167 CN 201110370167 A CN201110370167 A CN 201110370167A CN 102389465 B CN102389465 B CN 102389465B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating gastropathy, which is prepared by radix glehniae, radix paeoniae alba, red sage root, dandelion and Chinese angelica according to certain weight ratio. The traditional Chinese medicine composition can be prepared to any kinds of preparations for oral administration. The composition of the present invention has the efficacies of nourishing stomach and yin, and has fast effectiveness and high cure rate for treating various stomach diseases.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of gastropathy, belong to the field of Chinese medicines.
Background technology
Disease of stomach is one of common clinical, and clinical manifestation is: it is scorching hot, noisy like famine, dry mouth and tougue, constipation with dry stool to have a stomachache.Present clinical medicine for various treatment gastropathy, the chemicals curative effect is single, though therapeutic effect is fast, but side effect is big, various untoward reaction can appear in a lot of patients.Part treatment by Chinese herbs gastropathy, though side effect is little, it is slow to take effect, the course for the treatment of is long, increases patient's misery and financial burden virtually.Simultaneously, the scope of the Drug therapy disease of using is narrow at present, can only better action be arranged at 1-3 kind disease.Therefore, need provide that a kind of side effect is little, instant effect and eutherapeutic medicine.
Summary of the invention
The Chinese medicine composition that the purpose of this invention is to provide a kind of safe, eutherapeutic treatment gastropathy
Another object of the present invention provides the preparation method of this Chinese medicine composition.
Pharmaceutical composition of the present invention is selected Radix Glehniae, the Radix Paeoniae Alba, and Radix Salviae Miltiorrhizae, Herba Taraxaci and Radix Angelicae Sinensis make up, and make each medicine produce cooperative effect these drug regimens, thereby can reach more effective therapeutic effect.
Radix Glehniae (Radix Glehniae), nature and flavor are slightly cold, sweet in the mouth, little hardship.Function cures mainly: nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.It is thirsty to be used for lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound.
The Radix Paeoniae Alba (Paeonia sterniana Fletcher in Journ.), nature and flavor picric acid, cold; Go into liver, spleen channel.Nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Radix Salviae Miltiorrhizae, nature and flavor hardship, cold nature.The energy blood circulation promoting and blood stasis dispelling, removing heat from blood is calmed the nerves.Be used for menoxenia due to the blood stasis, dysmenorrhea, amenorrhea, puerperal the stasis of blood stomachache that stagnates; Angina pectoris, atherosclerosis; Chronic hepatitis, liver cirrhosis, abdominal masses or tumor; Chronic cardiopulmonary disease, bronchial asthma; Blood failing to tonify the heart or heart-fire are high partially, palpitation and restlessness, vexed insomnia.
Herba Taraxaci, nature and flavor are sweet, and little hardship is cold.Be used for heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.
Radix Angelicae Sinensis (Angelica sinensis), meridian distribution of property and flavor is warm in nature, sweet in the mouth, suffering.Return liver, the heart, spleen channel.Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Flos Carthami (Flos Carthami), property suffering, temperature.GUIXIN, Liver Channel; Promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.Fructus Crataegi has promoting digestion and removing stagnation, helps spleen stomach invigorating effect; Rhizoma Curcumae (Rhizoma Curcumae), nature and flavor suffering, hardship, temperature.Return liver, spleen channel.Have circulation of qi promoting removing food stagnancy, promoting blood circulation and stopping pain effect.
Radix Inulae, nature and flavor suffering, hardship, temperature.Return liver, spleen channel.Function with cure mainly: invigorating the spleen and regulating the stomach, promoting the flow of QI for relieving the stagnancy, pain relieving is antiabortive.Be used for the breast side of body, abdominal distention, vomiting dysentery, the breast side of body is dampened, and feels a pain in the chest when breathing and has a pain, frequent fetal movement.
Radix Glycyrrhizae has pain relieving, QI invigorating, emergency effect.Fructus Mume nature and flavor acid, puckery, flat.Return liver, spleen, lung, large intestine channel.Function cures mainly: astringe the lung, astringing intestine to stop diarrhea promotes the production of body fluid, relieving colic caused by ascaris.
The consumption of drug component of the present invention is also groped to sum up to draw through the inventor in a large number, and each amounts of components all has curative effect preferably in the following weight scope:
Radix Glehniae 10-20 part, Radix Paeoniae Alba 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Herba Taraxaci 10-20 part, Radix Angelicae Sinensis 10-15 part.
Preferably, Radix Glehniae 15-18 part, Radix Paeoniae Alba 10-15 part, Radix Salviae Miltiorrhizae 10-14 part, Herba Taraxaci 12-15 part, Radix Angelicae Sinensis 13-15 part
Further preferred, 14 parts of Radix Glehniaes, 17.5 parts of the Radix Paeoniae Albas, 14 parts of Radix Salviae Miltiorrhizaes, 17.5 parts of Herba Taraxacis, 12 parts of Radix Angelicae Sinensis
The medicine of the present invention further consumption of each component is Radix Glehniae 10-20 part, Radix Paeoniae Alba 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Herba Taraxaci 10-20 part, Radix Angelicae Sinensis 10-15 part, Flos Carthami 6-12 part, Fructus Crataegi 10-15 part, Rhizoma Curcumae 6-12 part.
Preferably, Radix Glehniae 15-18 part, Radix Paeoniae Alba 10-15 part, Radix Salviae Miltiorrhizae 10-14 part, Herba Taraxaci 12-15 part, Radix Angelicae Sinensis 13-15 part, Flos Carthami 8-10 part, Fructus Crataegi 12-15 part, Rhizoma Curcumae 8-10 part.
Further preferred, 14 parts of Radix Glehniaes, 17.5 parts of the Radix Paeoniae Albas, 14 parts of Radix Salviae Miltiorrhizaes, 17.5 parts of Herba Taraxacis, 12 parts of Radix Angelicae Sinensis, 10.5 parts on Flos Carthami, 12 parts of Fructus Crataegis, 10.5 parts of Rhizoma Curcumae.
The medicine of the present invention further consumption of each component is Radix Glehniae 10-20 part, Radix Paeoniae Alba 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Herba Taraxaci 10-20 part, Radix Angelicae Sinensis 10-15 part, Flos Carthami 6-12 part, Fructus Crataegi 10-15 part, Rhizoma Curcumae 6-12 part, Radix Inulae 4-10 part, Fructus Mume 1-5 part, Radix Glycyrrhizae 4-10 part.
Preferably, Radix Glehniae 15-18 part, Radix Paeoniae Alba 10-15 part, Radix Salviae Miltiorrhizae 10-14 part, Herba Taraxaci 12-15 part, Radix Angelicae Sinensis 13-15 part, Flos Carthami 8-10 part, Fructus Crataegi 12-15 part, Rhizoma Curcumae 8-10 part, Radix Inulae 4-6 part, Fructus Mume 2-3 part, Radix Glycyrrhizae 8-9 part.
Further preferred, 14 parts of Radix Glehniaes, 17.5 parts of the Radix Paeoniae Albas, 14 parts of Radix Salviae Miltiorrhizaes, 17.5 parts of Herba Taraxacis, 12 parts of Radix Angelicae Sinensis, 10.5 parts on Flos Carthami, 12 parts of Fructus Crataegis, 10.5 parts of Rhizoma Curcumae, 7 parts of Radix Inulaes, 3.5 parts of Fructus Mumes, 7 parts in Radix Glycyrrhizae.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.For example these crude drug grind into powder mix homogeneously can be made powder takes after mixing it with water; These crude drug decoctings can be condensed into decocting liquid then and make; But for each raw material that makes this medicine is brought into play drug effect better, preferably the Radix Inulae in the crude drug is added in water boiling back.But these can not be used for restriction protection scope of the present invention.
Preferably, the preparation method of medicine activity component of the present invention is as follows:
(1) with the above-mentioned raw materials medicine, decocts with water each 2-5 hour 2 times;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 90～95 ℃ and is about 1.30 extractum, drying, namely.
If in the medicine Radix Inulae is arranged, then preparation method is as follows:
(1) with the above-mentioned raw materials medicine, decocts with water, add Radix Inulae when water temperature reaches 100 ℃, decoct each 2-5 hour 2 times;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 90～95 ℃ and is about 1.30 extractum, drying, namely.
When in the preferred steps (1) medicine being decocted with water, preferably for the first time add 8 times of amounts of water, decocted 3 hours, add 6 times of amounts of water the second time, decocted 3 hours.
In the technology of the present invention step (2), behind extract dry, make preparation more according to a conventional method.For example, can be mixed and made into tablet, capsule, granule, oral liquid, slow releasing preparation, controlled release preparation, gel, ointment, ointment, cream, suppository, injection, injectable powder, patch, drop pill, suspensoid etc. with adjuvant on any or more than one pharmaceuticss such as starch, dextrin, lactose, microcrystalline Cellulose, hydroxypropyl methylcellulose, Polyethylene Glycol, magnesium stearate, micropowder silica gel, xylitol, lactose, glucose, glycine, sodium benzoate, mannitol, glycine etc.
Medicine of the present invention has the effect of yin nourishing stomach function regulating.Scorching hot to having a stomachache, noisy like famine, dry mouth and tougue, constipation with dry stool, superficial gastritis, chronic gastritis and various stomach discomfort all have better curative effect, instant effect cure rate height.
The test example
1, clinical data
1.1 diagnostic criteria
Diagnostic criteria with reference to CAG in " the sick learning of practical traditional Chinese medical science digestion ":
(1) prolonged and repeated outbreak or interruption outbreak gastral cavilty portion dull pain, distending pain, feed increases the weight of, and companion's belch is felt sick loss of appetite; (2) dark discomfort or the tenderness of pressing under epigastrium or the xiphoid-process can be arranged; (3) visible gastric mucosa presents obviously red and whitely under the gastroscope, and the mucous layer attenuation has the mucosa atrophy to change; (4) the histological examination mucous layer has inflammation and fibrosis, and body of gland reduces because destroying quantity, and it be slight atrophic gastritis that body of gland reduces＜1/3, the body of gland minimizing〉2/3 be the severe atrophic gastritis, between being the moderate atrophic gastritis between the two.
1.2 physical data
Whole 240 examples are divided into 4 groups at random, and every group of 60 examples are organized in treatment, man's 35,36,38,39 examples, and woman's 25,24,22,21 examples, 30 ~ 66 years old age, course of disease 3-5 14 examples, 6-10 22 examples, 10 years 24 examples.Matched group 60 examples, male 38 examples, women 22 examples, the age 31 ~ 64, course of disease 3-5 16 examples, 6-10 22 examples, 10 years 22 examples.Each organizes physical data comparing difference not statistically significant (P＞0.05).
2, Therapeutic Method
The treatment group: warm boiled water, 16g, every day 3 times, 3 months was 1 course for the treatment of.Matched group gives pepsin mixture (Jilin Li Hua pharmaceutical Co. Ltd, lot number 20110913) 10ml, and 3 ante cibum of every day are oral.Use antibiotic if the discovery Hp positive then adds, add medicine for stomach dynamic and analgesic in case of necessity to the ill, 3 months was 1 course for the treatment of.Observe the curative effect after two groups 2 courses for the treatment of, during avoid tobacco and wine, raw food and pungent stimulation.
3, criterion of therapeutical effect
Produce effects: clinical symptom disappearance, gastroscope and pathology check see that mucosa and body of gland atrophic lesion disappear substantially; Effectively: clinical symptoms disappears substantially, and gastroscope and pathology check see that the mucosa infringement takes a turn for the better; Invalid: clinical symptoms does not have improvement, and gastroscope and pathology check see that mucosa infringement nothing changes.
4, statistical method: adopt the SPSS11.0 statistical package to carry out statistical analysis, the relatively employing x of enumeration data rate
2Check, inspection level P=0.05.
5, result
The results are shown in Table 1
The zoopery of table 1 treatment urinary system infection
| Group | n | Produce effects | Effectively | Invalid | Total effective rate (%) |
| Embodiment four | 60 | 33 | 21 | 6 | 90.00%*# |
| Embodiment seven | 60 | 34 | 22 | 4 | 90.33%*# |
| Embodiment 13 | 60 | 35 | 23 | 3 | 95.00%*# |
| Matched group | 60 | 25 | 19 | 16 | 73.33% |
With matched group ratio, * P＜0.05; # P＞0.05
Effective 54 examples in embodiment four medication therapy groups 60 examples, total effective rate 90%; Effective 56 examples in embodiment seven medication therapy groups 60 examples, total effective rate 90.33%; Effective 57 examples in embodiment 13 medication therapy groups 60 examples, total effective rate 95%; Effective 44 examples in matched group 60 examples, total effective rate 73.33%; Difference has statistical significance (P＜0.05).The result shows, the embodiment of the invention four, seven and 13 medicine to treatment chronic atrophic gastritis and pepsin mixture group to having the obvious treatment effect frequently.There is not significant difference (P＞0.05) between the embodiment of the invention four, seven and 13.
The specific embodiment
Embodiment 1
(1) with Radix Glehniae 20g, Radix Paeoniae Alba 20g, Radix Salviae Miltiorrhizae 20g, Herba Taraxaci 20g, Radix Angelicae Sinensis 15g decocts with water 2 times, adds 8 times of amounts of water for the first time, decocts 3 hours, adds 6 times of amounts of water for the second time, decocts 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 95 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 2
(1) with Radix Glehniae 10g, Radix Paeoniae Alba 10g, Radix Salviae Miltiorrhizae 10g, Herba Taraxaci 10g, Radix Angelicae Sinensis 10g decocts with water 2 times, each 2 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 90 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 3
(1) with Radix Glehniae 11g, Radix Paeoniae Alba 17g, Radix Salviae Miltiorrhizae 15g, Herba Taraxaci 19g, Radix Angelicae Sinensis 12g decocts with water 2 times, each 5 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 95 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 4
(1) with Radix Glehniae 14g, Radix Paeoniae Alba 17.5g, Radix Salviae Miltiorrhizae 14g, Herba Taraxaci 17.5g, Radix Angelicae Sinensis 12g decocts with water 2 times, adds 8 times of amounts of water for the first time, decocts 3 hours, adds 6 times of amounts of water for the second time, decocts 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 95 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 5
(1) with Radix Glehniae 15g, Radix Paeoniae Alba 10g, Radix Salviae Miltiorrhizae 10g, Herba Taraxaci 12g, Radix Angelicae Sinensis 13g decocts with water 2 times, each 2.5 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 90 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 6
(1) with Radix Glehniae 18g, Radix Paeoniae Alba 15g, Radix Salviae Miltiorrhizae 14g, Herba Taraxaci 15g, Radix Angelicae Sinensis 15g decocts with water 2 times, each 2 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 94 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 7
(1) with Radix Glehniae 14g, Radix Paeoniae Alba 17.5g, Radix Salviae Miltiorrhizae 14g, Herba Taraxaci 17.5g, Radix Angelicae Sinensis 12g, Flos Carthami 10.5g, Fructus Crataegi 12g, Rhizoma Curcumae 10.5g decocts with water 2 times, adds 8 times of amounts of water for the first time, decocts 3 hours, adds 6 times of amounts of water for the second time, decocts 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 90 ℃ and is about 1.30 extractum, 3 parts of qinghuo reagents, and 4 parts in dextrin, 8 parts of cane sugar powders, mixing, drying is made granule.
Embodiment 8
With Radix Glehniae 10g, Radix Paeoniae Alba 10g, Radix Salviae Miltiorrhizae 10g, Herba Taraxaci 10g, Radix Angelicae Sinensis 10g, Flos Carthami 6g, Fructus Crataegi 10g, Rhizoma Curcumae 6g decocts with water 2 times, adds 8 times of amounts of water for the first time, decocts 3 hours, adds 6 times of amounts of water for the second time, decocts 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 90 ℃ and is about 1.30 extractum, 3 parts of qinghuo reagents, and 4 parts in dextrin, 8 parts of cane sugar powders, mixing, drying is made granule.
Embodiment 9
With Radix Glehniae 20g, Radix Paeoniae Alba 20g, Radix Salviae Miltiorrhizae 20g, Herba Taraxaci 20g, Radix Angelicae Sinensis 15g, Flos Carthami 12g, Fructus Crataegi 15g, Rhizoma Curcumae 12g decocts with water 2 times, adds 8 times of amounts of water for the first time, decocts 3 hours, adds 6 times of amounts of water for the second time, decocts 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 93 ℃ and is about 1.30 extractum, 3 parts of qinghuo reagents, and 4 parts in dextrin, 8 parts of cane sugar powders, mixing, drying is made granule.
Embodiment 10
With Radix Glehniae 15g, Radix Paeoniae Alba 10g, Radix Salviae Miltiorrhizae 10g, Herba Taraxaci 12g, Radix Angelicae Sinensis 13g, Flos Carthami 8g, Fructus Crataegi 12g, Rhizoma Curcumae 8g decocts with water 2 times, adds 8 times of amounts of water for the first time, decocts 3 hours, adds 6 times of amounts of water for the second time, decocts 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 91 ℃ and is about 1.30 extractum, 3 parts of qinghuo reagents, and 4 parts in dextrin, 8 parts of cane sugar powders, mixing, drying is made granule.
Embodiment 11
With Radix Glehniae 18g, Radix Paeoniae Alba 15g, Radix Salviae Miltiorrhizae 14g, Herba Taraxaci 15g, Radix Angelicae Sinensis 15g, Flos Carthami 10g, Fructus Crataegi 15g, Rhizoma Curcumae 10g decocts with water 2 times, adds 8 times of amounts of water for the first time, decocts 3 hours, adds 6 times of amounts of water for the second time, decocts 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 92 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 12
With Radix Glehniae 17g, Radix Paeoniae Alba 13g, Radix Salviae Miltiorrhizae 13g, Herba Taraxaci 14g, Radix Angelicae Sinensis 14g, Flos Carthami 9g, Fructus Crataegi 13g, Rhizoma Curcumae 9g decocts with water 2 times, adds 8 times of amounts of water for the first time, decocts 3 hours, adds 6 times of amounts of water for the second time, decocts 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 95 ℃ and is about 1.30 extractum, 3 parts of qinghuo reagents, and 4 parts in dextrin, 8 parts of cane sugar powders, mixing, drying is made granule.
Embodiment 13
(1) with Radix Glehniae 14g, Radix Paeoniae Alba 17.5g, Radix Salviae Miltiorrhizae 14g, Herba Taraxaci 17.5g, Radix Angelicae Sinensis 12g, Flos Carthami 10.5g, Fructus Crataegi 12g, Rhizoma Curcumae 10.5g, Fructus Mume 3.5g, Radix Glycyrrhizae 7g decocts with water, and adds Radix Inulae 7g when water temperature reaches 100 ℃, decoct 2 times, add 8 times of amounts of water for the first time, decocted 3 hours, for the second time add 6 times of amounts of water, decocted 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 90 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 14
(1) with Radix Glehniae 10g, Radix Paeoniae Alba 10g, Radix Salviae Miltiorrhizae 10g, Herba Taraxaci 10g, Radix Angelicae Sinensis 10g, Flos Carthami 6g, Fructus Crataegi 10g, Rhizoma Curcumae 6g, Fructus Mume 1g, Radix Glycyrrhizae 4g decocts with water, and adds Radix Inulae 4g when water temperature reaches 100 ℃, decocts 2 times, add for the first time 8 times of amounts of water, decocted 3 hours, and added 6 times of amounts of water for the second time, decocted 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 95 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 15
(1) with Radix Glehniae 20g, Radix Paeoniae Alba 20g, Radix Salviae Miltiorrhizae 20g, Herba Taraxaci 20g, Radix Angelicae Sinensis 15g, Flos Carthami 12g, Fructus Crataegi 15g, Rhizoma Curcumae 12g, Fructus Mume 5g, Radix Glycyrrhizae 10g decocts with water, and adds Radix Inulae 10g when water temperature reaches 100 ℃, decocts 2 times, add for the first time 8 times of amounts of water, decocted 3 hours, and added 6 times of amounts of water for the second time, decocted 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 94 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 16
(1) with Radix Glehniae 19g, Radix Paeoniae Alba 18g, Radix Salviae Miltiorrhizae 16g, Herba Taraxaci 11g, Radix Angelicae Sinensis 14g, Flos Carthami 7g, Fructus Crataegi 13g, Rhizoma Curcumae 8g, Fructus Mume 3g, Radix Glycyrrhizae 6g decocts with water, and adds Radix Inulae 7g when water temperature reaches 100 ℃, decocts 2 times, add for the first time 8 times of amounts of water, decocted 3 hours, and added 6 times of amounts of water for the second time, decocted 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 95 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 17
(1) with Radix Glehniae 15g, Radix Paeoniae Alba 10g, Radix Salviae Miltiorrhizae 10g, Herba Taraxaci 12g, Radix Angelicae Sinensis 13g, Flos Carthami 8g, Fructus Crataegi 12g, Rhizoma Curcumae 8g, Fructus Mume 2g, Radix Glycyrrhizae 8g decocts with water, and adds Radix Inulae 4g when water temperature reaches 100 ℃, decocts 2 times, add for the first time 8 times of amounts of water, decocted 3 hours, and added 6 times of amounts of water for the second time, decocted 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 90 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 18
(1) with Radix Glehniae 18g, Radix Paeoniae Alba 15g, Radix Salviae Miltiorrhizae 14g, Herba Taraxaci 15g, Radix Angelicae Sinensis 15g, Flos Carthami 10g, Fructus Crataegi 15g, Rhizoma Curcumae 10g, Fructus Mume 3g, Radix Glycyrrhizae 9g decocts with water, and adds Radix Inulae 6g when water temperature reaches 100 ℃, decocts 2 times, add for the first time 8 times of amounts of water, decocted 3 hours, and added 6 times of amounts of water for the second time, decocted 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 92 ℃ and is about 1.30 extractum, drying, namely.
Embodiment 19
(1) with Radix Glehniae 17g, Radix Paeoniae Alba 13.5g, Radix Salviae Miltiorrhizae 12.5g, Herba Taraxaci 14.5g, Radix Angelicae Sinensis 13.7g, Flos Carthami 8.6g, Fructus Crataegi 13.7g, Rhizoma Curcumae 9g, Fructus Mume 2.5g, Radix Glycyrrhizae 8.5g decocts with water, and adds Radix Inulae 5.5g when water temperature reaches 100 ℃, decocts 2 times, add for the first time 8 times of amounts of water, decocted 3 hours, and added 6 times of amounts of water for the second time, decocted 3 hours;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 95 ℃ and is about 1.30 extractum, drying, namely.
Claims (6)
1. a Chinese medicine composition for the treatment of gastropathy is characterized in that, it mainly is to be made by the following raw materials in weight medicine: Radix Glehniae 10-20 part, Radix Paeoniae Alba 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Herba Taraxaci 10-20 part, Radix Angelicae Sinensis 10-15 part;
The preparation method of described medicine comprises the steps:
(1) with the above-mentioned raw materials medicine, decocts with water each 2-5 hour 2 times;
(2) collecting decoction leaves standstill, and filters, and filtrate is concentrated into relative density for 90～95 ℃ and is about 1.30 extractum, drying, namely.
2. Chinese medicine composition according to claim 1, the consumption of described crude drug is: Radix Glehniae 15-18 part, Radix Paeoniae Alba 10-15 part, Radix Salviae Miltiorrhizae 10-14 part, Herba Taraxaci 12-15 part, Radix Angelicae Sinensis 13-15 part.
3. Chinese medicine composition according to claim 1, the consumption of described crude drug is: 14 parts of Radix Glehniaes, 17.5 parts of the Radix Paeoniae Albas, 14 parts of Radix Salviae Miltiorrhizaes, 17.5 parts of Herba Taraxacis, 12 parts of Radix Angelicae Sinensis.
4. medicine according to claim 1 is characterized in that, described crude drug also has: Flos Carthami 6-12 part, Fructus Crataegi 10-15 part, Rhizoma Curcumae 6-12 part.
5. medicine according to claim 4 is characterized in that, the consumption of each component is: Radix Glehniae 15-18 part, Radix Paeoniae Alba 10-15 part, Radix Salviae Miltiorrhizae 10-14 part, Herba Taraxaci 12-15 part, Radix Angelicae Sinensis 13-15 part, Flos Carthami 8-10 part, Fructus Crataegi 12-15 part, Rhizoma Curcumae 8-10 part.
6. medicine according to claim 4 is characterized in that, the consumption of each component is: 14 parts of Radix Glehniaes, 17.5 parts of the Radix Paeoniae Albas, 14 parts of Radix Salviae Miltiorrhizaes, 17.5 parts of Herba Taraxacis, 12 parts of Radix Angelicae Sinensis, 10.5 parts on Flos Carthami, 12 parts of Fructus Crataegis, 10.5 parts of Rhizoma Curcumae.
Priority Applications (1)
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| CN104436072B (en) * | 2014-12-22 | 2017-12-29 | 河南中医学院 | It is a kind of to treat deficiency of both qi and yin, the Chinese medicinal granule of damp and hot blood stasis type chronic atrophic gastritis |
| CN107198754A (en) * | 2016-03-16 | 2017-09-26 | 马丽宽 | A kind of Chinese medicine composition for removing intestines and stomach toxin poison dirt and protection intestinal mucosa |
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| CN101780258B (en) * | 2010-03-16 | 2011-12-21 | 江苏中兴药业有限公司 | Non-sucrose type shenmei stomach nourishing granule and preparation method thereof |
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| CN101780258B (en) * | 2010-03-16 | 2011-12-21 | 江苏中兴药业有限公司 | Non-sucrose type shenmei stomach nourishing granule and preparation method thereof |
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| 药典委员会.《第九册》.《卫生部颁药品标准中药成方制剂第九册》.1994, * |
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