CN101647961A - Medicament for gastric cancer and esophagus cancer during postoperation and chemotherapy and preparation method thereof - Google Patents
Medicament for gastric cancer and esophagus cancer during postoperation and chemotherapy and preparation method thereof Download PDFInfo
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- CN101647961A CN101647961A CN200910075357A CN200910075357A CN101647961A CN 101647961 A CN101647961 A CN 101647961A CN 200910075357 A CN200910075357 A CN 200910075357A CN 200910075357 A CN200910075357 A CN 200910075357A CN 101647961 A CN101647961 A CN 101647961A
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Abstract
The invention relates to a medicament for gastric cancer and esophagus cancer during postoperation and chemotherapy. The preparation method comprises the following steps: evenly mixing peach kernel, radix salviae miltiorrhizae, dried alum, oldenlandia, radix paeoniae alba, radix achyranthis bidentatae, dendrobe, paris polyphylla, radix polygonati officinalis, cortex moutan, asparagus fern, radix ophiopogonis, adenophora stricta, reed rhizome, liquorice, rhizoma anemarrhenae, golden cypress and subprostrate sophora, adding water for boiling twice, combining the liquid, condensing the liquid into thick paste with a relative density of 1.3, and drying and grinding the thick paste to prepare capsules. The medicament has obvious curative effect for treating qi-blood deficiency and deficiency ofqi and yin caused by operation or thermotherapy of gastric cancer and esophagus cancer, has an effective rate as high as 67.9 percent, can improve immunity of human bodies, improves the function of alimentary canal and has no toxic side effect.
Description
Technical field
The present invention relates to the medicine of a kind of gastric cancer, esophageal carcinoma postoperative or chemotherapeutic period, particularly relating to a kind of is the medicine that is used for gastric cancer, esophageal carcinoma postoperative or chemotherapeutic period of crude drug preparation with Chinese medicine.The invention still further relates to the preparation method of this medicine.
Background technology
Gastric cancer, esophageal carcinoma are modal malignant tumor, occupy very at high proportion in the alimentary system malignant tumour death.The traditional Chinese medical science is with categories such as gastric cancer ownership " stomachache ", " dysphagic ", " regurgitation ", " scar abdominal mass ", " gathering ", and how because of stomach stockpiles heat, heat is impairment of YIN so that consumption of YIN-fluid for a long time, depletion of body fluid causing lack of blood, stagnant heat stops gathering, stomach institute is dried withered, and be disease; Or melancholy impairing the spleen, damage of the spleen is depressed, and body fluid can not be failed cloth, poly-forms expectorant, angry impairing the liver, liver is felt frustrated strongly fragrant, and the sea of blood can not pass unimpeded, and is long-pending and be the stasis of blood, and phlegm and blood stasis then becomes lump; Or plain body loses emptyly, and dysfunction of the spleen in transportation makes the mental disorder stagnant heat knot of fighting, and the withered blood in Tianjin is withered and be disease.The traditional Chinese medical science is thought esophageal carcinoma pathogenesis basic, and body function descends for a little less than the deficiency of YANG QI, method of treatment emphasizes depressed liver-energy dispersing and QI regulating, sending down the abnormal ascending QI blood stasis dispelling, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, the body resistance strengthening and constitution consolidating, promote the production of body fluid moisturize, heat-clearing and toxic substances removing, anticancer analgetic, warming YANG and invigorating QI etc.
At present, gastric cancer, esophageal carcinoma adopt western medicine therapy more, mainly contain operative treatment and chemotherapy.And promptly have malnutrition, immunosuppressive condition and stress, cancer radical correction before the cancer patient art is traumatic bigger operation, will cause immunologic hypofunction, and symptom further increases the weight of.Chemotherapy is the common method of treatment gastric cancer and esophageal carcinoma, certain effect is arranged, but side effect is a lot, mainly comprises digestive tract reaction and bone marrow depression phenomenon.
The traditional Chinese medical science has special advantages aspect immunologic function degression that operation of gastric cancer, esophageal carcinoma and chemotherapy cause and the digestive tract reaction symptom improving, and has good treatment and improvement effect.
Summary of the invention
The purpose of this invention is to provide a kind of medicine that is used for gastric cancer, esophageal carcinoma postoperative or chemotherapeutic period, the big wound of QI and blood that this Drug therapy gastric cancer, esophageal carcinoma postoperative or chemotherapy cause, deficiency of both QI and YIN disease effect is obvious, can improve body immunity, improves digestive tract function.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Semen Persicae 10～20 Radix Salviae Miltiorrhizaes 25～35
Dried Alumen 5～15 Herba Hedyotidis Diffusaes 25～35
The Radix Paeoniae Alba 10～20 Radix Achyranthis Bidentataes 10～20
Herba Dendrobii 10～20 Rhizoma Paridis 10～20
Rhizoma Polygonati Odorati 25～35 Cortex Moutans 10～20
25～35 Radix Ophiopogonis 10～20 of Radix Asparagi
Radix Adenophorae (Radix Glehniae) 25～35 Rhizoma Phragmitiss 10～20
Radix Glycyrrhizae 5～15 Rhizoma Anemarrhenaes 5～15
Cortex Phellodendri 5～10 Radix Sophorae Tonkinensiss 10～20.
The preferred weight umber of described each component is:
Semen Persicae 15 Radix Salviae Miltiorrhizaes 30
Dried Alumen 10 Herba Hedyotidis Diffusaes 30
The Radix Paeoniae Alba 15 Radix Achyranthis Bidentataes 15
Herba Dendrobii 15 Rhizoma Paridis 15
Rhizoma Polygonati Odorati 30 Cortex Moutans 15
30 Radix Ophiopogonis 15 of Radix Asparagi
Radix Adenophorae (Radix Glehniae) 30 Rhizoma Phragmitiss 15
Radix Glycyrrhizae 10 Rhizoma Anemarrhenaes 10
Cortex Phellodendri 8 Radix Sophorae Tonkinensiss 15.
Said medicine can be made any dosage form on the pharmaceutics, as tablet, pill, powder, capsule etc., the preferred dosage form of the present invention is a capsule.
The concrete preparation method of above-mentioned each component being made medicine of the present invention is:
With above-mentioned Chinese medicine according to described parts by weight mix homogeneously, decoct with water 2 times, each 0.5～1 hour, merge 2 times decocting liquid, filter, be condensed into relative density and be 1.25～1.3 thick paste, after 50～60 ℃ of dryings, be ground into 100～120 purpose medicated powder, in incapsulating, sterilization makes the capsule product.
Immunologic function degression, digestive tract reaction that gastric cancer, esophageal carcinoma postoperative or chemotherapeutic period cause mainly show as lack of appetite, gastral cavity painful abdominal mass, pantothenic acid, xerostomia, feel sick, give birth in the pyretic toxicity, parched throat, constipation with dry stool, yellow urine is few, the upper abdomen hyperpyrexia has lump, red tongue not to have tire, full and rapid pulse, dark complexion.Zhang Zhongjing is pointed out, " spleen-QI being exuberant in the last month of each seasons is not subjected to heresy ", if insufficiency of the spleen mistake fortune, change source scarcity, healthy energy is lost empty, and all kinds of diseases and ailments are by life.In the prescription of the present invention, the Radix Paeoniae Alba, Radix Ophiopogonis, Cortex Phellodendri nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant, treatment fever due to yin deficiency, dryness of the intestine constipation, energy enhancing body cellular immune function; Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, Rhizoma Polygonati Odorati, Radix Glycyrrhizae, the sweet cold of Rhizoma Phragmitis, nourishing YIN to relieve dryness, to the big wound of gastric cancer excision back QI and blood, cloudy liquid consumption is hindered the deficiency of both QI and YIN symptom that causes, as dry mouth and throat, the soreness of waist, the few tongue of red tongue plays good improvement effect.Each component of this aspect focuses on blood circulation promoting and blood stasis dispelling, removes the rotten and lets fresh grow anti-cancer and detumescence, the nourishing the stomach spermatogenesis, the removing heat from blood attenuation is supported intestinal now, the big inconvenience of tonneau is hindered gastric cancer, esophageal carcinoma postoperative or chemotherapeutic period are cloudy, gives birth in the pyretic toxicity, mouth is drunk parched throat, constipation with dry stool; the few upper abdomen hyperpyrexia of yellow urine; lump, red and uncoated tongue are arranged, and full and rapid pulse, dark complexion have tangible curative effect.
For showing the immunity degradation that medicine of the present invention causes gastric cancer, esophageal carcinoma postoperative or chemotherapy, the therapeutic effect of digestive tract reaction, the present invention has carried out the clinical observation summary to 106 routine cases.
In the 106 routine cases, gastric cancer 60 examples, male 38 examples, women 22 examples, 32 examples of the treatment that wherein only undergos surgery undergo surgery and 28 examples of chemotherapy simultaneously.Esophageal carcinoma 46 examples, male 26 examples, women 20 examples, 19 examples of the treatment that wherein only undergos surgery undergo surgery and 27 examples of chemotherapy simultaneously.Above case clinical manifestation is all dry mouth and throat, constipation with dry stool, and yellow urine is few, and nervous heating has lump, red and uncoated tongue, rapid pulse is thin, dark complexion.
On the basis of original therapy, add medicine of the present invention, every day 3 times, each 2, one after each meal is taken observing effect after 3 months continuously, symptom appearance improvement in various degree in respect of 72 routine patients, effective percentage reaches 67.9%, normal person's 62 examples of defecation wherein, lump eliminator 58 examples, nervous heating condition improved person 48 examples, complexion improver's 52 examples.Clinical test results shows the big wound of QI and blood that medicine of the present invention causes for treatment gastric cancer, esophageal carcinoma postoperative or chemotherapy, and deficiency of both QI and YIN disease effect is obvious, can improve body immunity, improves digestive tract function, and does not have toxicity.
The specific embodiment
Embodiment 1
Get Semen Persicae 150g, Radix Salviae Miltiorrhizae 300g, dried Alumen 100g, Herba Hedyotidis Diffusae 300g, Radix Paeoniae Alba 150g, Radix Achyranthis Bidentatae 150g, Herba Dendrobii 150g, Rhizoma Paridis 150g, Rhizoma Polygonati Odorati 300g, Cortex Moutan 150g, Radix Asparagi 300g, Radix Ophiopogonis 150g, Radix Adenophorae (Radix Glehniae) 300g, Rhizoma Phragmitis 150g, Radix Glycyrrhizae 100g, Rhizoma Anemarrhenae 100g, Cortex Phellodendri 80g, Radix Sophorae Tonkinensis 150g mix homogeneously, add water to medicine is flooded, decocted 1 hour, leach decocting liquid, add water in the medicinal residues medicine is flooded, decocted 0.5 hour, merge 2 times decocting liquid, be condensed into the thick paste of relative density 1.3, after 60 ℃ of dryings, be ground into 120 purpose medicated powder, in incapsulating, sterilization makes the capsule product.
Embodiment 2
Get Semen Persicae 100g, Radix Salviae Miltiorrhizae 250g, dried Alumen 50g, Herba Hedyotidis Diffusae 250g, Radix Paeoniae Alba 100g, Radix Achyranthis Bidentatae 100g, Herba Dendrobii 100g, Rhizoma Paridis 100g, Rhizoma Polygonati Odorati 250g, Cortex Moutan 100g, Radix Asparagi 250g, Radix Ophiopogonis 100g, Radix Adenophorae (Radix Glehniae) 250g, Rhizoma Phragmitis 100g, Radix Glycyrrhizae 50g, Rhizoma Anemarrhenae 50g, Cortex Phellodendri 50g, Radix Sophorae Tonkinensis 100g mix homogeneously, add water to medicine is flooded, decocted 1 hour, leach decocting liquid, add water in the medicinal residues medicine is flooded, decocted 0.5 hour, merge 2 times decocting liquid, be condensed into the thick paste of relative density 1.25, after 50 ℃ of dryings, be ground into 100 purpose medicated powder, in incapsulating, sterilization makes the capsule product.
Embodiment 3
Get Semen Persicae 200g, Radix Salviae Miltiorrhizae 350g, dried Alumen 150g, Herba Hedyotidis Diffusae 350g, Radix Paeoniae Alba 200g, Radix Achyranthis Bidentatae 200g, Herba Dendrobii 200g, Rhizoma Paridis 200g, Rhizoma Polygonati Odorati 350g, Cortex Moutan 200g, Radix Asparagi 350g, Radix Ophiopogonis 200g, Radix Adenophorae (Radix Glehniae) 350g, Rhizoma Phragmitis 200g, Radix Glycyrrhizae 150g, Rhizoma Anemarrhenae 150g, Cortex Phellodendri 100g, Radix Sophorae Tonkinensis 200g mix homogeneously, add water to medicine is flooded, decocted 1 hour, leach decocting liquid, add water in the medicinal residues medicine is flooded, decocted 0.5 hour, merge 2 times decocting liquid, be condensed into the thick paste of relative density 1.3, after 60 ℃ of dryings, be ground into 120 purpose medicated powder, in incapsulating, sterilization makes the capsule product.
Claims (4)
1, a kind of medicine that is used for gastric cancer, esophageal carcinoma postoperative or chemotherapeutic period is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Semen Persicae 10～20 Radix Salviae Miltiorrhizaes 25～35
Dried Alumen 5～15 Herba Hedyotidis Diffusaes 25～35
The Radix Paeoniae Alba 10～20 Radix Achyranthis Bidentataes 10～20
Herba Dendrobii 10～20 Rhizoma Paridis 10～20
Rhizoma Polygonati Odorati 25～35 Cortex Moutans 10～20
25～35 Radix Ophiopogonis 10～20 of Radix Asparagi
Radix Adenophorae (Radix Glehniae) 25～35 Rhizoma Phragmitiss 10～20
Radix Glycyrrhizae 5～15 Rhizoma Anemarrhenaes 5～15
Cortex Phellodendri 5～10 Radix Sophorae Tonkinensiss 10～20.
2, the medicine that is used for gastric cancer, esophageal carcinoma postoperative or chemotherapeutic period according to claim 1 is characterized in that the parts by weight of described each component are:
Semen Persicae 15 Radix Salviae Miltiorrhizaes 30
Dried Alumen 10 Herba Hedyotidis Diffusaes 30
The Radix Paeoniae Alba 15 Radix Achyranthis Bidentataes 15
Herba Dendrobii 15 Rhizoma Paridis 15
Rhizoma Polygonati Odorati 30 Cortex Moutans 15
30 Radix Ophiopogonis 15 of Radix Asparagi
Radix Adenophorae (Radix Glehniae) 30 Rhizoma Phragmitiss 15
Radix Glycyrrhizae 10 Rhizoma Anemarrhenaes 10
Cortex Phellodendri 8 Radix Sophorae Tonkinensiss 15.
3, the medicine that is used for gastric cancer, esophageal carcinoma postoperative or chemotherapeutic period according to claim 1 and 2 is characterized in that described medicine is made capsule.
4, the described preparation method that is used for the medicine of gastric cancer, esophageal carcinoma postoperative or chemotherapeutic period of claim 3, be according to described parts by weight mix homogeneously with above-mentioned Chinese medicine, decoct with water 2 times, each 0.5～1 hour, merge 2 times decocting liquid, filter, be condensed into relative density and be 1.25～1.3 thick paste, after 50～60 ℃ of dryings, be ground into 100～120 purpose medicated powder, in incapsulating, sterilization makes the capsule product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910075357A CN101647961A (en) | 2009-09-08 | 2009-09-08 | Medicament for gastric cancer and esophagus cancer during postoperation and chemotherapy and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910075357A CN101647961A (en) | 2009-09-08 | 2009-09-08 | Medicament for gastric cancer and esophagus cancer during postoperation and chemotherapy and preparation method thereof |
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| CN101647961A true CN101647961A (en) | 2010-02-17 |
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| CN200910075357A Pending CN101647961A (en) | 2009-09-08 | 2009-09-08 | Medicament for gastric cancer and esophagus cancer during postoperation and chemotherapy and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102114152A (en) * | 2011-03-23 | 2011-07-06 | 许文成 | Medicament for radically curing incapability of eating or drinking during advanced esophageal cancer and preparation method thereof |
| CN102302691A (en) * | 2011-09-01 | 2012-01-04 | 田艳梅 | Herbal tea for eliminating discomfort of patient after operation and preparation method for herbal tea |
| CN104667002A (en) * | 2015-03-10 | 2015-06-03 | 济南骄泰信息技术有限公司 | Medicine for treating stomach cancer |
| CN104784421A (en) * | 2015-05-04 | 2015-07-22 | 刘中远 | Herbal diet formula beneficial to postoperative recovery of stomach cancer and preparation method thereof |
-
2009
- 2009-09-08 CN CN200910075357A patent/CN101647961A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102114152A (en) * | 2011-03-23 | 2011-07-06 | 许文成 | Medicament for radically curing incapability of eating or drinking during advanced esophageal cancer and preparation method thereof |
| CN102114152B (en) * | 2011-03-23 | 2012-02-15 | 许文成 | Medicament for advanced esophageal cancer and preparation method thereof |
| CN102302691A (en) * | 2011-09-01 | 2012-01-04 | 田艳梅 | Herbal tea for eliminating discomfort of patient after operation and preparation method for herbal tea |
| CN104667002A (en) * | 2015-03-10 | 2015-06-03 | 济南骄泰信息技术有限公司 | Medicine for treating stomach cancer |
| CN104784421A (en) * | 2015-05-04 | 2015-07-22 | 刘中远 | Herbal diet formula beneficial to postoperative recovery of stomach cancer and preparation method thereof |
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