CN101695534B - Chinese patent medicament for treating mammary gland disease - Google Patents

Chinese patent medicament for treating mammary gland disease Download PDF

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CN101695534B
CN101695534B CN2009100663066A CN200910066306A CN101695534B CN 101695534 B CN101695534 B CN 101695534B CN 2009100663066 A CN2009100663066 A CN 2009100663066A CN 200910066306 A CN200910066306 A CN 200910066306A CN 101695534 B CN101695534 B CN 101695534B
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CN101695534A (en
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李培丙
李四强
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Abstract

The invention relates to Chinese patent medicament for treating a mammary gland disease. The medicine comprises the following raw material medicaments in part by weight: 250 to 1500 parts of torrefied crab, 10 to 30 parts of Chinese eaglewood and 15 to 40 parts of sanchi. The medicine is prepared by: roasting a whole crab for 1 to 2 hours at a temperature between 80 and 200 DEG C; crushing the whole crab, and passing an 80 to 120-mesh screen; and evenly mixing crab powder with other components to prepare powders. Practice proves that the medicament is reasonable in compatibility and good in synergy effect, can treat both tip and root, can effectively treat diseases such as mastocarcinoma, acute and chronic mastitis and the like, and has the cure rate over 90 percent for treating the mastocarcinoma and the cure rate over 95 percent for people with the mastitis and mammary gland hyperplasia. The disease is not easy to relapse after being cured, and the effect is good. The Chinese patent medicament has the advantages of simple formula, low cost, fewer expenses of the patients, medication safety and no toxic or side effects, and is easy to be accepted by the patients.

Description

The Chinese patent medicine of treatment mastopathy
One, technical field:
The present invention relates to a kind of Chinese patent medicine, particularly relate to a kind of Chinese patent medicine for the treatment of mastopathy.
Two, background technology:
Cystic hyperplasia of breast is common clinical, frequently-occurring disease, occupies the majority with female patient, has female patient more than 25% that in various degree mastopathy is arranged according to statistics approximately.In mastopathy, cystic hyperplasia of breast, mastitis and breast carcinoma account for more than 70%, age of onset is more common in the 25-50 age group in year, the course of disease is different in size, short then several months, the long then several years shows as breast periodically pain and mammary gland tumor, have a strong impact on women's physical and mental health, influence work and life.It is diversified suffering from the mastopathy reason, with people's aspects such as life style, dietary structure, home environment and inherited genetic factors relation is arranged all.It is reported that breast carcinoma is that sickness rate is more a kind of than higher in the malignant tumor, in the world, its sickness rate is the highest.The sickness rate of China is lower comparatively speaking, but its every year is just with 2%~5% speed increment.
Treatment breast disease method has Therapeutic Method such as hormone therapy, operation and Chinese medicine for oral administration at present.Wherein operative treatment is more common, though determined curative effect, it costs an arm and a leg, and the postoperative patient physical recovery is slower, is difficult for being accepted by extensive patients.Hormone therapy method for oral administration, side effect is bigger, and easily recurrence can not be eradicated source of disease, and the expense costliness, seldom adopts.With treatment by Chinese herbs tumor history early, and on oncotherapy, accumulated a large amount of square medicines.Chinese and Western medicine has been compared many characteristics, and the antitumaous effect of Western medicine is very fast, but toxic and side effects is big; The antitumaous effect of the traditional Chinese medical science is slow, but efficacy consolidation, toxic and side effects is little, is easily accepted by the patient.Modern pharmacological research shows that Chinese medicine not only can improve immunologic functions such as immune surveillance, immunologic cytotoxicity, can also induce differentiation, promotes apoptosis of tumor cells.But some Chinese medicines are cut in uncertain therapeutic efficacy aspect the treatment breast disease at present, instability, and easily recurrence can not tackle the problem at its root.
Application number is 200710012737.5 patent application, a kind of medicated wine for the treatment of cyclomastopathy is disclosed, medicine consists of Eriocheir sinensis 500~800g, Spica Prunellae 30~50g, Semen Vaccariae 30~50g, Flos Carthami 30~50g, earlier with Eriocheir sinensis slurrying, Spica Prunellae, Semen Vaccariae and Flos Carthami are ground into powder, and putting into the immersion of 1000ml Chinese liquor became medicated wine after 30 days, was mainly used in the treatment cyclomastopathy, the curative effect of this medicated wine is indeterminate, and curative effect is undesirable.
The patent No. is 200510047791.4 a kind of treatment cystic hyperplasia of breast that is used to take orally of patent disclosure and the Chinese medicine of mastitis and the preparation method of Film coated tablets thereof, and crude drug is Cornu Cervi, Herba Taraxaci, Thallus Laminariae (Thallus Eckloniae), Radix Trichosanthis, Caulis Spatholobi, Radix Notoginseng, Radix Paeoniae Rubra, Sargassum, Radix Rhapontici, the Radix Aucklandiae, Radix Scrophulariae, Cortex Moutan, Spica Prunellae, Fructus Forsythiae, Flos Carthami, microcrystalline Cellulose, 95% ethanol and CaSO 4It is said that this medicine can dwindle lump in breast, alleviate the carbuncle of breast pain.But this medicine ingredient is more, and preparation is inconvenient, and cost is higher, and curative effect is also not ideal.
Three, summary of the invention:
The technical problem to be solved in the present invention: provide that a kind of prescription is simple, expense is low, can effectively treat mastotic Chinese patent medicine.
Technical scheme of the present invention:
A kind of Chinese patent medicine for the treatment of mastopathy represents that with weight portion crude drug is composed of the following components, dries 250~1500 parts of Eriocheir sinensiss, 10~30 parts of Lignum Aquilariae Resinatum, 15~40 parts of Radix Notoginseng.
The Chinese patent medicine of described treatment mastopathy wherein dries 300~1000 parts of Eriocheir sinensiss, 10~30 parts of Lignum Aquilariae Resinatum, 20~35 parts of Radix Notoginseng.
The Chinese patent medicine of described treatment mastopathy wherein dries 350~800 parts of Eriocheir sinensiss, 15~25 parts of Lignum Aquilariae Resinatum, 20~30 parts of Radix Notoginseng.
The described following method of Eriocheir sinensis employing of drying obtains, and full Eriocheir sinensis under 80~200 ℃ condition, was toasted 1~2 hour, through pulverizing, crosses 80~120 mesh sieves.
Described Chinese patent medicine is powder, capsule, tablet or pill.
Consumption and instructions of taking:
Press powder and calculate, 20~30 grams of taking medicine every day, each once took in 2 hours after meal sooner or later.When taking, take with brewageing grain wine, 15~30 days is a course of treatment, and take effect general one to two course of treatment, and cure three to six courses of treatment.
Pharmacology analysis of the present invention:
Lignum Aquilariae Resinatum among the present invention, fragrant, the lignum aquilariae resinatum of another name honey, QI regulating medicine, warm in nature, hot, bitter, return spleen, stomach, kidney channel, cure mainly promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, helping inspiration to relieve asthma." Variorum of Shennong " record: this medicine energy " it is swollen to treat the grandular plague poison ".Radix Notoginseng, another name Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), Typhonium flagelliforme (Lodd.) Blume, hardship warm in nature, sweet, little; Return liver, stomach warp; Cure mainly the dissipating blood stasis hemostasis, subduing swelling and relieving pain; Promoting blood circulation and detumescence, eliminating stasis to stop pain, but blood circulation promoting and blood stasis dispelling, the pain relieving effect is better.
Eriocheir sinensis, another name Eriocheir sinensis, eriocheir sinensis are not only the cuisines dish, as medicinal special effect are arranged also.Motherland's medical science thinks that Eriocheir sinensis salty in the mouth cold in nature, crab meat have heat clearing away, diffusing blood agglomeration, Radix Dipsaci to hinder, manage through functions such as normal pulse YIN nourishing; But its shell heat-clearing and toxic substances removing, the broken clear long-pending pain relieving of becoming silted up.Supplement to the Herbal record: " its merit is not only loose, and energy and blood are also "; Put down in writing according to " occupying the diet spectrum ": " mend bone marrow, liver nourishing the moon fills gastric juice, and nourishing muscle and tendon is invigorated blood circulation, and controls more nuclear of cellulitis " with breath.Record in modern age " Chinese medicine voluminous dictionary ", Eriocheir sinensis have effects such as " heat clearing away, the blood that looses, continuous exhausted the wound controlled bones and muscles injury, scabies, dermatitis rhus, scald ".
Three medicines are share, the drug effect complementation, synergism strengthens, and helps promoting curative effect.
Positive beneficial effect of the present invention:
(1) the present invention is according to traditional Chinese medical science traditional theory, just sum up out through for many years exploration, test, facts have proved that this compatibility of drugs is reasonable, synergy is good, and treating both the principal and secondary aspects of a disease can effectively be treated diseases such as breast carcinoma, acute and chronic mastitis, improve patient's immunity, especially to early stage patient with breast cancer, cure rate height, cure rate reach more than 90%; Mastitis, cyclomastopathy patient's cure rate are reached more than 95%; Be difficult for recurrence after curing, effect is better.In addition, this medicine also has obvious curative effects to other mastopathy such as diseases such as mammary gland fibroma, galactocele.
(2) the present invention is pure tcm product, and prescription is simple, expense is low, and the patient spends few., compare during breast carcinoma especially for treatment, have instant effect, patient's misery is little, cost is low clear superiority with traditional radiotherapy chemotherapy method.In addition, this medicinal medicine safety, without any side effects is easily accepted by the patient.
(3) take with grain wine during drug administration of the present invention, taking convenience, and help improving curative effect.
Curative effect statistics and model case:
The curative effect statistics: prescription of the present invention is a secret prescription handed down in the family from generation to generation, has gone through and has passed several generations, and the case of healing is countless, now only carries out statistical analysis with regard to the 120 routine cases of having treated since in March, 2004.
In 120 routine patients, women's 116 examples, male's 4 examples, the age is between 20~70 years old.The patient has patients such as breast carcinoma, mastitis, cyclomastopathy, and the treatment effective percentage is 100%; Obvious to mastitis, cyclomastopathy effect, cure rate reaches more than 95.0%; The breast carcinoma cure rate reaches more than 90%.The patient cures the symptom appearance repeatedly of the no state of an illness in back.
Model case:
1. Wang, the woman, 62 years old, people from Zhoukou City, Henan went examination in hospital to make a definite diagnosis and suffer from breast carcinoma, did chemotherapy in hospital in May, 2005, and symptom is alleviated to some extent, the recurrence again in back five months of going home, all money of family has all been used up.Find the inventor in October, 2006 under the situation of being driven into a corner, according to dosage take medicament of the present invention, every day twice, each 20 grams take with brewageing grain wine, and 30 days is a course of treatment.Two the course of treatment rear udder attachment lump diminish, pain relief, in succession take four courses of treatment after, remove examination in hospital again, find that lump disappears, no pain symptom, and two courses of treatment of medication return to one's perfect health, do not recur so far.
2. Guo, the woman, 35 years old, people from Taikang County, Henan, nipple and mammary areola are unusual, and the nipple erosion is gone examination in hospital to make a definite diagnosis and is suffered from breast carcinoma.Begin according to dosage to take medicament of the present invention in February, 2004, every day 2 times, each 20 grams, 30 days is a course of treatment.The rotten to the corn transference cure of nipple after two courses of treatment, again three courses of treatment of continuous use, nipple and mammary areola are normal, go examination in hospital to find that breast carcinoma disappears, and medication is consolidated a course of treatment, not recurrence so far.
3. Zhang, the woman, 32 years old, the nipple twinge appearred in people from Xinyang, Henan during suckling, and smouldered smooth, cracked nipple with milk, and symptom such as breast local swelling pain is made a definite diagnosis on inspection and is suffered from acute mastitis then.Begin according to dosage to take medicament of the present invention in August, 2007, every day 2 times, each 20 grams, 20 days is a course of treatment.Sx after two courses of treatment, mammary swelling pain disappears, and cracked nipple disappears.And medication is consolidated a course of treatment, healing fully, not recurrence so far.
4. Lee, the woman, 45 years old, people from Xinyang, Henan, the breast red and swollen heat pain is about 10 days, and there is lump in breast central authorities, by it fluctuation are arranged, local pyrexia, tenderness is obvious, and puncture suction has pus, goes examination in hospital to make a definite diagnosis and suffers from acute and chronic mastitis.Begin according to dosage to take this medicament in April, 2008, after two courses of treatment, lump in breast diminishes, the local pyrexia transference cure, and no tenderness sense, and two courses of treatment of medication, not recurrence so far, curative effect is better.
5. Chen, the woman, 48 years old, people from Zhoukou City, Henan, the nipple erosion, simultaneously with the surrounding skin edema, pachyderma, coarse, the breast surface temperature is higher, goes examination in hospital to make a definite diagnosis and suffers from breast carcinoma.Begin according to dosage to take this medicament in April, 2009, after two courses of treatment, symptom is clearly better, and nipple is no longer rotten to the corn, the hydroderma transference cure.And with two courses of treatment of this medicine, all transference cures are cured fully, not recurrence so far, and curative effect is better.
6. Chen, the woman, 50 years old, people from Taikang County, Henan had breast inflammation and history of pain repeatedly, inflammatory masses and masses occurred around the breast, was diagnosed as chronic fistula type mastitis, and the course of disease is more than 2 years.Begin according to dosage to take medicament of the present invention in January, 2009, every day 2 times, each 30 grams, 30 days is a course of treatment.After three courses of treatment, the transference cure of suppurating, lump in breast diminishes, and symptom is clearly better.And four courses of treatment of medication, all transference cures, not recurrence so far, curative effect is better.
Four, the specific embodiment:
Embodiment 1: the mastotic Chinese patent medicine of a kind of treatment, composition is: dry Eriocheir sinensis, Lignum Aquilariae Resinatum, Radix Notoginseng, concrete composition sees Table 1.
Method for making: full Eriocheir sinensis under 80~120 ℃ condition, was toasted 1~1.5 hour, dries, pulverize, cross 80~120 mesh sieves and Lignum Aquilariae Resinatum, panax mixed evenly after, make powder.
Embodiment 2: the mastotic Chinese patent medicine of a kind of treatment, composition sees Table 1.
Full Eriocheir sinensis under 120~160 ℃ condition, was toasted 1.5~2 hours, dries, pulverize, cross 80~120 mesh sieves and Lignum Aquilariae Resinatum, panax mixed evenly after, make capsule according to a conventional method, consumption and usage are with reference to powder.
Embodiment 3: the mastotic Chinese patent medicine of a kind of treatment, composition sees Table 1.
Full Eriocheir sinensis under 150~200 ℃ condition, was toasted 1.5~2 hours, dries, pulverize, cross 80~120 mesh sieves and Lignum Aquilariae Resinatum, panax mixed evenly after, make tablet or pill according to a conventional method.Consumption and usage are with reference to powder.
Embodiment 4~26: the concrete composition of medicine sees Table 1, and method for making no longer repeats with embodiment 1.
Ingredient among table 1: the embodiment 1~26
Figure G2009100663066D00061

Claims (6)

1. a Chinese patent medicine for the treatment of mastopathy is characterized in that: represent that with weight portion crude drug is composed of the following components, dry 250~1500 parts of Eriocheir sinensiss, 10~30 parts of Lignum Aquilariae Resinatum, 15~40 parts of Radix Notoginseng.
2. the Chinese patent medicine of treatment mastopathy according to claim 1 is characterized in that: wherein dry 300~1000 parts of Eriocheir sinensiss, 10~30 parts of Lignum Aquilariae Resinatum, 20~35 parts of Radix Notoginseng.
3. the Chinese patent medicine of treatment mastopathy according to claim 1 is characterized in that: wherein dry 350~800 parts of Eriocheir sinensiss, 15~25 parts of Lignum Aquilariae Resinatum, 20~30 parts of Radix Notoginseng.
4. the Chinese patent medicine of treatment mastopathy according to claim 1 is characterized in that: described to dry Eriocheir sinensis be to adopt following method to make, and full Eriocheir sinensis under 80~200 ℃ condition, toast 1~2 hour, through pulverizing mistake 80~120 mesh sieves.
5. according to the Chinese patent medicine of each described treatment mastopathy of claim 1-4, it is characterized in that: described Chinese patent medicine is a powder.
6. according to the Chinese patent medicine of each described treatment mastopathy of claim 1-4, it is characterized in that: capsule, tablet or the pill of described Chinese patent medicine for making according to a conventional method.
CN2009100663066A 2009-10-30 2009-10-30 Chinese patent medicament for treating mammary gland disease Active CN101695534B (en)

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