CN101780197B - Drug for treating gastric cancer - Google Patents

Abstract

The invention relates to a traditional Chinese medicine composition for treating gastric cancer, which selects raw traditional Chinese medicinal materials capable of building up resistance to disease and eliminating the pathogenic factor, removing qi stagnation and helping digestion, reinforcing the spleen and strengthening the stomach, stopping and cooling blood, relaxing bowel, relieving stomach cold and indigestion and loss of appetite, activating qi depression to blood stasis, softening hard lumps and dispeling nodes, removing putrefaction and promoting tissue regeneration and eradicating helicobacter pylori. The raw traditional Chinese medicinal materials are boiled in water or crushed to be prepared into a decoction or a pill to be taken. According to the early, middle and later stages of the condition of the gastric cancer, the composition is taken according to symptoms. The composition is characterized in that the traditional Chinese medicine capable of activating blood, removing blood stasis, resolving masses, removing dampness by means of aromatics, and strengthening the spleen and stomach are mainly selected, and the selected raw traditional Chinese medicinal materials are as follows: barbated skullcup herb, arnebia root, fortune drynaria rhizome, sedge grass, herba solani lyrati, interspersion, seaweed, semen momordicae (unshelled), green common aucklandia root, largehead atractylodes rhizome, Ardisia brevicaulis Diels , hirudo, Herba sedi Aizoon and kummerowia striata ( Japan clover herb). In 150 people who persist in treatment, 80 cases are cured, and the cure rate is 53.3%; 40 cases produce effects, and the obvious effective rate is 26.7%; 25 cases are effective, and the effective rate is 16.7%; 5 cases are ineffective, and the inefficiency is 3.3%; and the total effective rate is 96.7%.

Description

A kind of medicine for the treatment of gastric cancer

[technical field] the present invention relates to a kind of medicine for the treatment of gastric cancer, belongs to technical field of Chinese medicines.

[background technology] gastric cancer is one of common malignancy, accounts for first of China's malignant tumor of digestive tract, the 3rd of general tumour.Age of onset with 40-60 year for seeing more.The man is about 3: 10 more than the woman, and gastric cancer can occur in any position of stomach, sees gastric antrum at most, is lesser gastric curvature secondly, is cardia once more, and greater gastric curvature and antetheca are less.The cause of disease of gastric cancer is still indeterminate, but think mostly, relevant with factors such as heredity, blood group, body constitution, race and living habit, occupation, dietetic variety, drinking-water, hobby, ambient soils, wherein important with life, dietary habit and heredodiathesis, some disease of stomach may cancerate carcinogenic as chronic atrophic gastritis, gastric ulcer, polyp of stomach etc.Stomach Helicobacter pylori may be the major reason of incidence gastric cancer.Just because of be that deep and remote pylori is infectious, make the incidence gastric cancer rate of China in rising trend always.At present, Western medicine is to the just operation cutting of gastric cancer therapy, radiation and chemotherapy, the method for this surgical operation therapy and chemotherapy radiotherapy, not only expense height, and mortality rate height is even the patient survives death, but tend to cause intraperitoneal pus infections or extensively adhesion, the patient is caused adverse consequences.

Still there is demand in the Chinese medicine preparation that [summary of the invention] present people better treat gastric cancer to curative effect, up to now, also not having to find has medicine than standard to inhomogeneity gastric cancer, the inventor just works as the Chinese medicine apprentice, digs medicine, pharmacy, medication from little, nearly 60 years Chinese traditional treatment practice is arranged, finally work out a kind of oral medicinal herb medicine for the treatment of gastric cancer, thereby finished the present invention.

The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of gastric cancer, choice of drug can strengthening vital QI to eliminate pathogenic factors, removing heat from blood, loosening bowel to relieve constipation are good for the stomach, stop blooding in removing food stagnancy relieving dyspepsia, spleen reinforcing, the releasing cold syndrome of the stomach is indigestion and loss of appetite, the activation qi depression to blood stasis, hard masses softening and resolving, putrefaction-removing granulation-promoting and the Chinese crude drug raw material of killing helicobacter pylori are through decocting in water or pulverizing, make decoction or pill, take; Be divided into initial stage, mid-term, later stage three phases according to the gastric cancer state of an illness, symptoms first, the intermediary and later stages are respectively: the initial stage---generally do not have obvious positive sign, Most patients only dark tenderness occurs in epigastrium except that the whole body situation is more weak.Mid-term---show that gastric cancer development enlarges, especially soak into and penetrate serous coat and when invading pancreas, persistence can occur to have an intense pain, and to the lower back radiation, the absorption of cancerous protuberance toxin, the patient becomes thin day by day, weak, anemia, is dyscrasia.Later stage---cancerous protuberance continues to grow up, and symptom occurs blocking, and cancer causes the difficulty of swallowing at the bottom of cardia, the stomach, and gastric cancer causes the pyloric obstruction symptom, and abdominal part also can touch lump, and hematemesis and melena appear in the cancerous protuberance superficial ulcer, proves that focus shifts, ascites occurs.Take medicine to the ill, the initial stage is chosen the hot damp eliminating of dispelling, heat-clearing and toxic substances removing is main, and the intermediary and later stages select for use and invigorate blood circulation, the Chinese medicine of blood stasis dispelling, light hard eliminating stagnation, removing dampness by means of aromatics, strengthening the spleen and nourishing the stomach is main.The raw material of Chinese medicine that initial stage selects for use has:

Radix Astragali 15-20g Rhizoma Atractylodis Macrocephalae (parched) 15-20g Pumex 30g

Rhizoma Pinelliae 15g rhizoma sparganic 20-30g Rhizoma Curcumae 20-30g Concha Arcae 20-30g

Rhizoma Cyperi 20-30g Fructus Amomi 15-20g

The crude drug of intermediate gastric carcinoma:

Radix Codonopsis 15-20g Poria 10-15g Cacumen Platycladi preparata 5-10g

Semen Raphani 15-20g Radix Linderae 10-20g Olibanum 10-15g

Myrrha 10-15g Radix Paeoniae Alba (parched) 2-30g Cortex Magnoliae Officinalis 15-20g

Semen Pharbitidis (having another name called HEIQIANNIU flower seed) 6g-8g Semen Pharbitidis (having another name called white morning glory seeds) 6g-8g

Fructus Crataegi 15-20g Endothelium Corneum Gigeriae Galli 10-20g

The crude drug of late gastric cancer:

Herba Scutellariae Barbatae 20-30g Radix Arnebiae (Radix Lithospermi) 10-20g Rhizoma Drynariae 20-30g

Rhizoma Cyperi 20-30g Herba Solani Lyrati 10-15g Thallus Laminariae (Thallus Eckloniae) 15-20g

Sargassum 15-20g Semen Momordicae (shelling) 2-4g Radix Aristolochiae 10-15g

Three liang of gold of Rhizoma Atractylodis Macrocephalae 15-20g (another name Rhizoma Belamcandae) 20-30g

Hirudo 5-10g Typhonium flagelliforme (Lodd.) Blume 10-15g Kummerowia striata (Thunb.) Schindl (another name male and female grass) 20-30g

Medicine of the present invention can take the conventional method of Chinese medicine preparation to make any conventional oral preparations, the most frequently used is the Chinese medicine water to be decocted make decoction, or Chinese medicine powder is broken into powder, make capsule or again with powder mixes evenly after, mix conventional adjuvant and make pill or tablet.During treatment, use the prescription in early stage, mid-term, late period respectively, symptomatic treatment.

When taking medicine, be generally one after each meal, 1 pair of dosage of drug of decoction every day divides to take for 3 times, and 30 days is a course of treatment, and early gastric cancer 1-3 is healed a course of treatment entirely, and heal intermediate gastric carcinoma 2-4 the course of treatment entirely, and heal late gastric cancer 3-5 the course of treatment entirely.

Points for attention: will remove thought pressure during the treatment, keep happy, avoid sad, worried, can not weigh physical sport, have many meals but little food at eath, note nutrition, discontinue the habit of smoking and drinking, forbid eating and drinking too much at one meal.

Medicine material of the present invention adopts traditional Chinese medicine principle, summarizes the experience out in conjunction with the clinical practice in more than 60 year of the inventor, and through up to a hundred patients' use, effective percentage is more than 96%.

One, physical data: accept 150 examples altogether for medical treatment, male 100 examples, women 50 examples, the oldest 65 years old, minimum 30 years old, the course of disease was long 4 years, and short 2 years, hospital's photo is all arranged, be diagnosed as the patient of gastric cancer.

Two, criterion of therapeutical effect: 1, produce effects: clinical symptom disappearance or basic the disappearance, gastroscopy pathology report gastrointestinal epithelialization is given birth to and atypical hyperplasia disappears, or alleviates more than 2 level degree; 2, effective: clinical symptoms obviously alleviates, and gastroscopy pathology report gastrointestinal epithelialization is given birth to and atypical hyperplasia alleviates more than 1 level degree; 3, invalid: clinical symptoms does not have improvement, gastroscopy pathology report no change.

Three, Therapeutic Method: according to patient's the state of an illness, use the medicine of the present invention in initial stage, mid-term or later stage respectively, every day one pair of pharmaceutical quantities, divide and take for three times, take half an hour after meal, 30 days is a course of treatment, initial stage carninomatosis 1-3 can be healed a course of treatment entirely, can heal full intermediate gastric carcinoma 2-4 the course of treatment, and later stage gastric cancer 3-5 can be healed period in a medicine a course of treatment entirely, control the emotion of self, take a good rest, discontinue the habit of smoking and drinking, forbid eating and drinking too much at one meal.

Four, therapeutic outcome: adhere to 150 philtrums for the treatment of, cure 80 examples, cure rate 53.3%, produce effects 40 examples, obvious effective rate 26.7%, effective 25 examples, effective percentage 16.7%, invalid 5 examples, inefficiency 3.3%, total effective rate 96.7%.

Five, case introduction:

1, open * *, man, 45 years old, people from Anxiang County, Hunan Province, when go to a doctor in February, 2007, private prosecution stomach pain gas acid half a year, be diagnosed as the gastric cancer that causes by superficial gastritis through examination in hospital, the medicine of employing initial stage gastric cancer, the two weeks feels pain of taking medicine alleviates, and takes one and a half months pain and disappears, and feed is normal, hospital's check enteric epitheliumization and atypical hyperplasia disappear substantially, and be healthy so far.

2, beam * *, man, 60 years old, Zhou Jiadian people from town, Dingcheng district, Changde City suffers from atrophic gastric cancer a year and a half, seeks medical advice and do not feel any better in many places, come to go to a doctor the back with later stage gastric cancer medicine, serve on 30 days, every day 1 pair of Chinese medicine dosage, condition of illness obviously alleviates, obey 60 days medicinal liquids altogether, symptom disappears substantially, and the amount of having a meal heightens, hospital claims the gastric cancer transference cure during check.

3, Pang Dongxiu, woman, 56 years old, people from Nan County, Hunan Province.Because of getting a cancer of the stomach, many places are cured and are not felt any better, and introduce in October, 2008 through other people and come to see a doctor, due to illness journey adopts the mid-term medicine that it is treated only one year, takes medicine decoction 40 days in mid-term continuously, every day one pair of medicament amount, divide three times taking medicine before meal usefulness, condition of illness disappears substantially as a result, consciously feel good, it is normal substantially to have a meal, because financial difficulties in the family, do not continue medication, but drug withdrawal visits after half a year, patient's private prosecution is not bitterly, had a meal normally, thanked endlessly repeatedly.

Claims (1)

1. Chinese medicine composition for the treatment of the gastric cancer later stage, it is characterized in that: described Chinese medicine composition is made up of following traditional Chinese medicine raw: Herba Scutellariae Barbatae 20-30g, Radix Arnebiae (Radix Lithospermi) 10-20g, Rhizoma Drynariae 20-30g, Rhizoma Cyperi 20-30g, Herba Solani Lyrati 10-15g, Thallus Laminariae (Thallus Eckloniae) 15-20g, Sargassum 15-20g, Semen Momordicae 2-4g, Radix Aristolochiae 10-15g, Rhizoma Atractylodis Macrocephalae 15-20g, three liang of golden 20-30g, Hirudo 5-10g, Typhonium flagelliforme (Lodd.) Blume 10-15g, Kummerowia striata (Thunb.) Schindl 20-30g.