CN103212020B

CN103212020B - Traditional Chinese medicine composition for treating functional dyspepsia

Info

Publication number: CN103212020B
Application number: CN201310085695.3A
Authority: CN
Inventors: 吕春阳; 赵霞
Original assignee: Individual
Current assignee: Lv Chunyang
Priority date: 2013-03-18
Filing date: 2013-03-18
Publication date: 2014-09-24
Anticipated expiration: 2033-03-18
Also published as: CN103212020A

Abstract

The invention relates to a traditional Chinese medicine composition for treating functional dyspepsia. The composition is composed of the following traditional Chinese medicine raw materials by weight: 10-25 parts of Forsythia, 5-20 parts of bupleurum, 10-30 parts of dandelion, 5-20 parts of cassia twig, 5-20 parts of Sparganium stoloniferum, 5-20 parts of curcuma zedoary, 10-25 parts of fried hawthorn, 10-25 parts of fried medicated leaven, 10-25 parts of fried malt, 10-25 parts of Radix Aucklandiae, 5-20 parts of immature bitter orange, 5-20 parts of endothelium corneum gigeriae galli, 10-25 parts of semen Raphani, 5-20 parts of gardenia, 10-25 parts of Poria, 10-25 parts of Magnolia officinalis and 10-25 parts of polygonatum. The traditional Chinese medicine composition provided by the invention has efficacies of strengthening the spleen and stomach, soothing the liver, purging intense heat, eliminating dampness, alleviating fullness, promoting the circulation of qi and removing food retention, significant effect in the treatment of functional dyspepsia and reliable effect; and the components have advantages of wide medicine sources, simple preparation and no toxic or side effects.

Description

A kind of Chinese medicine composition for the treatment of functional dyspepsia

Technical field

The present invention relates to a kind of not medicinal preparation of definite structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of functional dyspepsia.

Background technology

Dyspepsia is a kind of clinical syndrome, by the caused disease of gastric motility disorder, also comprises that gastroparesis and esophageal regurgitation that gastric peristalsis is bad are sick.Generally show as abdominal distention, easily full, acid regurgitation, belch, the symptoms such as that some patients also have is nauseating, vomiting.Dyspepsia is mainly divided into functional dyspepsia and Organic dyspepsia, and most dyspepsias are the functional dyspepsia (>50%) that is difficult to find the definite cause of disease.Organic dyspepsia has the clear and definite cause of disease, as peptic ulcer, erosive gastritis, esophagitis and malignant tumor etc.Functional dyspepsia refers to that the course of disease is more than 6 months, involves the non-ucler dyspepsia that indigestion symptom surpasses 3 months.Cardinal symptom is epigastrium pain, epigastrium burn feeling, glutted or early full after the meal, and routine examination does not find to explain the organic disease of symptom.At present, there is no clinically the method for radical cure, just take and alleviate or control symptom is therapeutic goal.Conventional cushion kind comprises: press down sour medicine, dynamics-promoting medicine, mucosa protection medicine, psychology and spiritual regulating drug etc., exist the deficiency of easily repeatedly showing effect after drug withdrawal.

The traditional Chinese medical science thinks, functional dyspepsia belongs to the categories such as " gastral cavity painful abdominal mass ", " stomachache ", " noisy " of the traditional Chinese medical science, and its disease, at stomach, relates to the internal organs such as liver spleen, should determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.Its pathogenic factor is mainly that diet retardance, damp and hot middle resistance, feelings will are become estranged, weakness of the spleen and stomach, and basic pathogenesis is middle burnt disorder of QI movement, taste lifting dereliction of duty.

According to theory of Chinese medical science, for the pathogeny of functional dyspepsia, carry out dialectical composition of prescription, take invigorating the spleen and regulating the stomach, depressed liver-energy dispersing and QI regulating, dyspepsia and intestinal stasis relieving is the rule for the treatment of, to reach the object for the treatment of both the principal and the secondary aspects of a disease at the same time.

Summary of the invention

In order to overcome prior art western medicines in treatment functional dyspepsia, exist after drug withdrawal easily the deficiency of outbreak repeatedly, the invention provides a kind ofly prepare conveniently, medicine source is wide, cost is low, the Chinese medicine composition of evident in efficacy, reliable effect, the treatment functional dyspepsia that has no side effect.

The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of functional dyspepsia, it is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: Fructus Forsythiae 10-25 part, Radix Bupleuri 5-20 part, Herba Taraxaci 10-30 part, Ramulus Cinnamomi 5-20 part, rhizoma scirpi 5-20 part, Rhizoma Curcumae 5-20 part, Fructus Crataegi (parched) 10-25 part, Massa Medicata Fermentata (parched) 10-25 part, Fructus Hordei Germinatus (parched) 10-25 part, Radix Aucklandiae 10-25 part, Fructus Aurantii Immaturus 5-20 part, Endothelium Corneum Gigeriae Galli 5-20 part, Semen Raphani 10-25 part, Fructus Gardeniae 5-20 part, Poria 10-25 part, Cortex Magnoliae Officinalis 10-25 part, Rhizoma Polygonati Odorati 10-25 part.

The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of functional dyspepsia, is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: 15 parts of Fructus Forsythiaes, 12 parts of Radix Bupleuri, 20 parts of Herba Taraxacis, 12 parts of Ramulus Cinnamomi, 10 parts of rhizoma scirpis, 10 parts of Rhizoma Curcumae, 15 parts of Fructus Crataegi (parched), 15 parts of Massa Medicata Fermentata (parched), 15 parts of Fructus Hordei Germinatus (parched)s, 15 parts of the Radix Aucklandiae, 12 parts of Fructus Aurantii Immaturuss, 10 parts of Endothelium Corneum Gigeriae Galli, 15 parts of Semen Raphanis, 10 parts of Fructus Gardeniaes, 15 parts, Poria, 15 parts of Cortex Magnoliae Officinalis, 15 parts of Rhizoma Polygonati Odorati.

Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: Fructus Forsythiae has the effect of heat-clearing and toxic substances removing, mass dissipating and swelling eliminating; Radix Bupleuri have evacuate bring down a fever, the effect of yang invigorating soothing liver-QI; Herba Taraxaci has the effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Ramulus Cinnamomi has the effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; Rhizoma scirpi has the effects such as blood stasis dispelling stimulates the menstrual flow, removing blood stasis eliminating mass, circulation of qi promoting removing food stagnancy; Rhizoma Curcumae has the effect of circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving; Fructus Crataegi (parched) has the effect of dyspepsia and intestinal stasis relieving, phlegm reduction of blood circulation promoting; Massa Medicata Fermentata (parched) has and eats the effect of the stomach that disappears; Fructus Hordei Germinatus (parched) has promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back the effect of newborn relieving distension; The Radix Aucklandiae has the effect of intestinal stasis relieving in promoting the circulation of QI to relieve pain, tune; Fructus Aurantii Immaturus has the effect of the loose painful abdominal mass of reducing phlegm, dispelling the stagnated QI removing food stagnancy; Endothelium Corneum Gigeriae Galli has the effect of promoting digestion and invigorating the stomach, eliminate indigestion calculus, astringency inducing reducing urination, arresting seminal emission; Semen Raphani has the effect of the de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm; Fructus Gardeniae has the effect of pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Poria has the effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Cortex Magnoliae Officinalis has circulation of qi promoting removing food stagnancy, dampness except effect full, lowering the adverse QI to relieve asthma; Rhizoma Polygonati Odorati has the effect of nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.Drug component in the present composition is through dialectical compatibility, helps using mutual assistant, has synergism, plays altogether invigorating the spleen and regulating the stomach, soothing the liver pathogenic fire purging, dampness except effect full, circulation of qi promoting removing food stagnancy, functional dyspepsia reached to the object for the treatment of both the principal and the secondary aspects of a disease at the same time.

The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, does not occur toxic and side effects, total effective rate 95.3%, cure rate reaches 65.6%.

The specific embodiment

Below in conjunction with embodiment, the present invention will be further described.

Embodiment 1

Treat a Chinese medicine composition for functional dyspepsia, its raw material of Chinese medicine by following weight proportion forms: Fructus Forsythiae 15g, Radix Bupleuri 12g, Herba Taraxaci 20g, Ramulus Cinnamomi 12g, rhizoma scirpi 10g, Rhizoma Curcumae 10g, Fructus Crataegi (parched) 15g, Massa Medicata Fermentata (parched) 15g, Fructus Hordei Germinatus (parched) 15g, Radix Aucklandiae 15g, Fructus Aurantii Immaturus 12g, Endothelium Corneum Gigeriae Galli 10g, Semen Raphani 15g, Fructus Gardeniae 10g, Poria 15g, Cortex Magnoliae Officinalis 15g, Rhizoma Polygonati Odorati 15g.

Embodiment 2

Treat a Chinese medicine composition for functional dyspepsia, its raw material of Chinese medicine by following weight proportion forms: Fructus Forsythiae 10g, Radix Bupleuri 20g, Herba Taraxaci 25g, Ramulus Cinnamomi 5g, rhizoma scirpi 12g, Rhizoma Curcumae 20g, Fructus Crataegi (parched) 10g, Massa Medicata Fermentata (parched) 25g, Fructus Hordei Germinatus (parched) 12g, Radix Aucklandiae 20g, Fructus Aurantii Immaturus 5g, Endothelium Corneum Gigeriae Galli 20g, Semen Raphani 25g, Fructus Gardeniae 5g, Poria 20g, Cortex Magnoliae Officinalis 12g, Rhizoma Polygonati Odorati 20g.

Embodiment 3

Treat a Chinese medicine composition for functional dyspepsia, its raw material of Chinese medicine by following weight proportion forms: Fructus Forsythiae 20g, Radix Bupleuri 5g, Herba Taraxaci 30g, Ramulus Cinnamomi 10g, rhizoma scirpi 20g, Rhizoma Curcumae 15g, Fructus Crataegi (parched) 20g, Massa Medicata Fermentata (parched) 12g, Fructus Hordei Germinatus (parched) 25g, Radix Aucklandiae 10g, Fructus Aurantii Immaturus 10g, Endothelium Corneum Gigeriae Galli 12g, Semen Raphani 20g, Fructus Gardeniae 10g, Poria 25g, Cortex Magnoliae Officinalis 10g, Rhizoma Polygonati Odorati 12g.

Embodiment 4

Treat a Chinese medicine composition for functional dyspepsia, its raw material of Chinese medicine by following weight proportion forms: Fructus Forsythiae 25g, Radix Bupleuri 10g, Herba Taraxaci 15g, Ramulus Cinnamomi 15g, rhizoma scirpi 5g, Rhizoma Curcumae 12g, Fructus Crataegi (parched) 12g, Massa Medicata Fermentata (parched) 20g, Fructus Hordei Germinatus (parched) 10g, Radix Aucklandiae 25g, Fructus Aurantii Immaturus 15g, Endothelium Corneum Gigeriae Galli 15g, Semen Raphani 12g, Fructus Gardeniae 15g, Poria 10g, Cortex Magnoliae Officinalis 25g, Rhizoma Polygonati Odorati 10g.

Embodiment 5

Treat a Chinese medicine composition for functional dyspepsia, its raw material of Chinese medicine by following weight proportion forms: Fructus Forsythiae 12g, Radix Bupleuri 15g, Herba Taraxaci 10g, Ramulus Cinnamomi 20g, rhizoma scirpi 15g, Rhizoma Curcumae 5g, Fructus Crataegi (parched) 25g, Massa Medicata Fermentata (parched) 10g, Fructus Hordei Germinatus (parched) 20g, Radix Aucklandiae 12g, Fructus Aurantii Immaturus 20g, Endothelium Corneum Gigeriae Galli 5g, Semen Raphani 10g, Fructus Gardeniae 20g, Poria 12g, Cortex Magnoliae Officinalis 20g, Rhizoma Polygonati Odorati 25g.

Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 8 centimetres of powder, decoct, adopt intense fire to decoct before at a simmer, after boiling with slow fire boiling 20～30 minutes; Second decocts, and adds water and does not have approximately 5 centimetres of powder, decocts, and after water boils, decocts 15～20 minutes.Twice decoction extracting juice that removes slag, merges.

Treat a Chinese medicine composition for functional dyspepsia, clinical efficacy is summed up:

One, general data: this Chinese medicine composition is applied to clinical observation case 64 examples, male 36 examples wherein, female's 28 examples, 20～70 years old age.The shortest person of the course of disease 3 months, elder reaches 10 years, average 7 months.

Two, diagnosis basis

1, gastral cavilty portion pain, often accompanies the diseases such as the vexed or distension of painful abdominal mass, belch, pantothenic acid, noisy, nausea and vomiting;

2, morbidity normal with feelings will not freely, eating and drinking without temperance, fatigue, the factor such as catch cold be relevant;

3, upper digestive tract barium meal x-ray inspection, fibergastroscope and histopathology biopsy etc., the pathological changes such as visible Gastroduodenal mucosal lesions inflammation, ulcer;

4, stool or vomitus occult blood test strong positive person, prompting Complicated by Hemorrhage of Digestive Tract ';

5, B ultrasonic, liver function, angiocholegraphy contribute to Differential Diagnosis.

Three, usage and dosage: during clinical practice, the component in compositions, consumption are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.Within five days, be a course for the treatment of, one day potion, the about 300ml of twice extracting juice of decocting, minute early, late twice half an hour ante cibum warm taking.Period in a medicine avoids eating anything raw or cold, the thing of pungent, stimulation.

Four, criterion of therapeutical effect:

(1) cure: clinical symptom disappearance;

(2) take a turn for the better: clinical symptoms partly disappears or obviously alleviates;

(3) invalid: clinical symptoms is without improving or increasing the weight of.

Five, therapeutic effect: in this clinical observation case, take medicine 1-6 the course for the treatment of, cure 42 examples, 19 examples that take a turn for the better, invalid 3 examples.During treatment, there is not toxic and side effects.

Six, model case:

Case 1:

In certain, female, 30 years old, operating pressure was large, did not like food, distension after food, stomach has burning sensation, especially obvious before going to a doctor.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom disappears substantially; Continue to strengthen 1 course for the treatment of, the healing that all disappears of all symptoms.

Case 2:

Beam, man, 62 years old.Private prosecution when medical: stomach distending pain after meal, have heartburn, acid regurgitation sense, constipation.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, after conscious medicine, abdominal distention, gastral cavilty distension slightly alleviate, and do not occur heartburn, acid regurgitation, arteries and veins slight force; Continuous take 1 course for the treatment of, abdominal distention, gastral cavilty distension are not obvious; Diet increases, comfortable in stomach after food; Stool once a day, not dry not rare; Without singultus, heartburn, acid regurgitation symptom; Consolidate and take 1 course for the treatment of again, transference cure, appetite increases, energetic.

Claims

1. a Chinese medicine composition for the treatment of functional dyspepsia, is characterized in that: its raw material of Chinese medicine by following weight proportion forms: Fructus Forsythiae 15g, Radix Bupleuri 12g, Herba Taraxaci 20g, Ramulus Cinnamomi 12g, rhizoma scirpi 10g, Rhizoma Curcumae 10g, Fructus Crataegi (parched) 15g, Massa Medicata Fermentata (parched) 15g, Fructus Hordei Germinatus (parched) 15g, Radix Aucklandiae 15g, Fructus Aurantii Immaturus 12g, Endothelium Corneum Gigeriae Galli 10g, Semen Raphani 15g, Fructus Gardeniae 10g, Poria 15g, Cortex Magnoliae Officinalis 15g, Rhizoma Polygonati Odorati 15g.