Background technology
Dyspepsia is a kind of clinical syndrome, by the caused disease of gastric motility disorder, also comprises gastroparesis and esophageal regurgitation disease that gastric peristalsis is bad.Generally show as abdominal distention, easily full, acid regurgitation, belch, symptoms such as that the patient who has also has is nauseating, vomiting.Dyspepsia mainly is divided into functional dyspepsia and organic dyspepsia, and most dyspepsias are the functional dyspepsia (〉 50% that is difficult to find the definite cause of disease).Organic dyspepsia has the clear and definite cause of disease, as peptic ulcer, erosive gastritis, esophagitis and malignant tumor etc.Functional dyspepsia refers to the course of disease more than 6 months, involves the non-ucler dyspepsia that indigestion symptom surpasses 3 months.Cardinal symptom is epigastrium pain, epigastrium burn feeling, glutted or early full after the meal, and routine examination does not find to explain the organic disease of symptom.At present, not having the method for radical cure clinically, is therapeutic goal with alleviation or controlling symptoms just.Cushion kind commonly used comprises: but sour medicine, dynamics-promoting medicine, mucosa protection medicine, psychology and spirit are regulated medicine etc., exist the deficiency of easily showing effect repeatedly after the drug withdrawal.
The traditional Chinese medical science thinks, functional dyspepsia belongs to categories such as " gastral cavity painful abdominal mass ", " stomachache ", " noisy " of the traditional Chinese medical science, and its disease relates to internal organs such as liver spleen at stomach, suitable determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs.Its pathogenic factor mainly be diet retardance, damp and hot in resistance, feelings will become estranged, weakness of the spleen and stomach, basic pathogenesis is middle burnt disorder of QI movement, taste lifting dereliction of duty.
According to theory of Chinese medical science, at the pathogeny of functional dyspepsia, carry out dialectical composition of prescription, be the rule of treatment with invigorating the spleen and regulating the stomach, depressed liver-energy dispersing and QI regulating, dyspepsia and intestinal stasis relieving, to reach the purpose for the treatment of both the principal and the secondary aspects of a disease at the same time.
Summary of the invention
Exist after the drug withdrawal easily the deficiency of outbreak repeatedly in order to overcome prior art western medicines in treatment functional dyspepsia, the invention provides a kind ofly prepare conveniently, the medicine source is wide, cost is low, the Chinese medicine composition of evident in efficacy, reliable effect, the treatment functional dyspepsia that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of functional dyspepsia, it is characterized in that: it is made up of following Chinese medicinal raw materials in portion by weight: Fructus Forsythiae 10-25 part, Radix Bupleuri 5-20 part, Herba Taraxaci 10-30 part, Ramulus Cinnamomi 5-20 part, rhizoma scirpi 5-20 part, Rhizoma Curcumae 5-20 part, Fructus Crataegi (parched) 10-25 part, Massa Medicata Fermentata (parched) 10-25 part, Fructus Hordei Germinatus (parched) 10-25 part, Radix Aucklandiae 10-25 part, Fructus Aurantii Immaturus 5-20 part, Endothelium Corneum Gigeriae Galli 5-20 part, Semen Raphani 10-25 part, Fructus Gardeniae 5-20 part, Poria 10-25 part, Cortex Magnoliae Officinalis 10-25 part, Rhizoma Polygonati Odorati 10-25 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of functional dyspepsia is characterized in that: it is made up of following Chinese medicinal raw materials in portion by weight: 15 parts of Fructus Forsythiaes, 12 parts of Radix Bupleuri, 20 parts of Herba Taraxacis, 12 parts of Ramulus Cinnamomi, 10 parts of rhizoma scirpis, 10 parts of Rhizoma Curcumae, 15 parts of Fructus Crataegi (parched), 15 parts of Massa Medicata Fermentata (parched), 15 parts of Fructus Hordei Germinatus (parched)s, 15 parts of the Radix Aucklandiae, 12 parts of Fructus Aurantii Immaturuss, 10 parts of Endothelium Corneum Gigeriae Galli, 15 parts of Semen Raphanis, 10 parts of Fructus Gardeniaes, 15 parts in Poria, 15 parts of Cortex Magnoliae Officinalis, 15 parts of Rhizoma Polygonati Odorati.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In the Chinese medicine composition of the present invention: Fructus Forsythiae has the effect of heat-clearing and toxic substances removing, mass dissipating and swelling eliminating; Radix Bupleuri have evacuate bring down a fever, the effect of yang invigorating soothing liver-QI; Herba Taraxaci has the effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Ramulus Cinnamomi has the effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; Rhizoma scirpi has effects such as blood stasis dispelling stimulates the menstrual flow, removing blood stasis eliminating mass, circulation of qi promoting removing food stagnancy; Rhizoma Curcumae has circulation of qi promoting removing blood stasis, removing food stagnancy analgesic effect; Fructus Crataegi (parched) has the effect of dyspepsia and intestinal stasis relieving, phlegm reduction of blood circulation promoting; Massa Medicata Fermentata (parched) has and eats the effect of the stomach that disappears; Fructus Hordei Germinatus (parched) has promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back the effect of newborn relieving distension; The Radix Aucklandiae has the effect of intestinal stasis relieving in promoting the circulation of QI to relieve pain, the accent; Fructus Aurantii Immaturus has the effect of the diffusing painful abdominal mass of reducing phlegm, dispelling the stagnated QI removing food stagnancy; Endothelium Corneum Gigeriae Galli has the effect of promoting digestion and invigorating the stomach, eliminate indigestion calculus, astringency inducing reducing urination, arresting seminal emission; Semen Raphani have help digestion remove to expand, the effect of lowering the adverse-rising QI to resolve phlegm; Fructus Gardeniae has the effect of pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Poria has the effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Cortex Magnoliae Officinalis has the circulation of qi promoting removing food stagnancy, dampness is removed effect full, lowering the adverse QI to relieve asthma; Rhizoma Polygonati Odorati has the effect of nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.Drug component in the present composition is through dialectical compatibility, helps using mutual assistant, has synergism, plays invigorating the spleen and regulating the stomach, soothing the liver pathogenic fire purging, dampness altogether and removes effect full, the circulation of qi promoting removing food stagnancy, functional dyspepsia reached the purpose for the treatment of both the principal and the secondary aspects of a disease at the same time.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, the medicine source is wide, cost is low.It follows the prescription principle of medication of the traditional Chinese medical science, and various component drug adopt the usefulness that is decocted in water for oral dose.Through the clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, toxic and side effects do not occur, total effective rate 95.3%, cure rate reaches 65.6%.
The specific embodiment
The present invention will be further described below in conjunction with embodiment.
Embodiment 1
A kind of Chinese medicine composition for the treatment of functional dyspepsia, it is made up of following Chinese medicine raw materials by weight proportion: Fructus Forsythiae 15g, Radix Bupleuri 12g, Herba Taraxaci 20g, Ramulus Cinnamomi 12g, rhizoma scirpi 10g, Rhizoma Curcumae 10g, Fructus Crataegi (parched) 15g, Massa Medicata Fermentata (parched) 15g, Fructus Hordei Germinatus (parched) 15g, Radix Aucklandiae 15g, Fructus Aurantii Immaturus 12g, Endothelium Corneum Gigeriae Galli 10g, Semen Raphani 15g, Fructus Gardeniae 10g, Poria 15g, Cortex Magnoliae Officinalis 15g, Rhizoma Polygonati Odorati 15g.
Embodiment 2
A kind of Chinese medicine composition for the treatment of functional dyspepsia, it is made up of following Chinese medicine raw materials by weight proportion: Fructus Forsythiae 10g, Radix Bupleuri 20g, Herba Taraxaci 25g, Ramulus Cinnamomi 5g, rhizoma scirpi 12g, Rhizoma Curcumae 20g, Fructus Crataegi (parched) 10g, Massa Medicata Fermentata (parched) 25g, Fructus Hordei Germinatus (parched) 12g, Radix Aucklandiae 20g, Fructus Aurantii Immaturus 5g, Endothelium Corneum Gigeriae Galli 20g, Semen Raphani 25g, Fructus Gardeniae 5g, Poria 20g, Cortex Magnoliae Officinalis 12g, Rhizoma Polygonati Odorati 20g.
Embodiment 3
A kind of Chinese medicine composition for the treatment of functional dyspepsia, it is made up of following Chinese medicine raw materials by weight proportion: Fructus Forsythiae 20g, Radix Bupleuri 5g, Herba Taraxaci 30g, Ramulus Cinnamomi 10g, rhizoma scirpi 20g, Rhizoma Curcumae 15g, Fructus Crataegi (parched) 20g, Massa Medicata Fermentata (parched) 12g, Fructus Hordei Germinatus (parched) 25g, Radix Aucklandiae 10g, Fructus Aurantii Immaturus 10g, Endothelium Corneum Gigeriae Galli 12g, Semen Raphani 20g, Fructus Gardeniae 10g, Poria 25g, Cortex Magnoliae Officinalis 10g, Rhizoma Polygonati Odorati 12g.
Embodiment 4
A kind of Chinese medicine composition for the treatment of functional dyspepsia, it is made up of following Chinese medicine raw materials by weight proportion: Fructus Forsythiae 25g, Radix Bupleuri 10g, Herba Taraxaci 15g, Ramulus Cinnamomi 15g, rhizoma scirpi 5g, Rhizoma Curcumae 12g, Fructus Crataegi (parched) 12g, Massa Medicata Fermentata (parched) 20g, Fructus Hordei Germinatus (parched) 10g, Radix Aucklandiae 25g, Fructus Aurantii Immaturus 15g, Endothelium Corneum Gigeriae Galli 15g, Semen Raphani 12g, Fructus Gardeniae 15g, Poria 10g, Cortex Magnoliae Officinalis 25g, Rhizoma Polygonati Odorati 10g.
Embodiment 5
A kind of Chinese medicine composition for the treatment of functional dyspepsia, it is made up of following Chinese medicine raw materials by weight proportion: Fructus Forsythiae 12g, Radix Bupleuri 15g, Herba Taraxaci 10g, Ramulus Cinnamomi 20g, rhizoma scirpi 15g, Rhizoma Curcumae 5g, Fructus Crataegi (parched) 25g, Massa Medicata Fermentata (parched) 10g, Fructus Hordei Germinatus (parched) 20g, Radix Aucklandiae 12g, Fructus Aurantii Immaturus 20g, Endothelium Corneum Gigeriae Galli 5g, Semen Raphani 10g, Fructus Gardeniae 20g, Poria 12g, Cortex Magnoliae Officinalis 20g, Rhizoma Polygonati Odorati 25g.
Chinese medicine composition in embodiment of the invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soaked 15~20 minutes, add water again and do not have about 8 centimetres of powder, decoct, at a simmer preceding employing intense fire decocts, and slow fire boiling 20~30 minutes are used in the back of boiling; Second decocts, and adds water and does not have about 5 centimetres of powder, decocts, and decocts 15~20 minutes after water boils.Twice decoction extracting juice that removes slag merges.
A kind of Chinese medicine composition for the treatment of functional dyspepsia, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to clinical observation case 64 examples, wherein male 36 examples, women 28 examples, 20~70 years old age.The shortest person of the course of disease 3 months, elder reaches 10 years, average 7 months.
Two, diagnosis basis
1, gastral cavilty portion pain is often accompanied diseases such as the vexed or distension of painful abdominal mass, belch, pantothenic acid, noisy, nausea and vomiting;
2, morbidity normal with feelings will not freely, eating and drinking without temperance, fatigue, factor such as catch cold be relevant;
3, upper digestive tract barium meal X ray examination, fibergastroscope and histopathology biopsy etc., pathological changes such as visible stomach, duodenal mucosa inflammation, ulcer;
4, stool or vomitus occult blood test strong positive person point out concurrent digestive tract hemorrhage;
5, B ultrasonic, liver function, angiocholegraphy help Differential Diagnosis.
Three, usage and dosage: during clinical practice, the component in the compositions, consumption are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.Five days is a course of treatment, one day potion, the about 300ml of twice extracting juice of decocting, divide early, late twice half an hour ante cibum warm taking.Period in a medicine avoids eating anything raw or cold, the thing of pungent, stimulation.
Four, criterion of therapeutical effect:
(1) cures: clinical symptom disappearance;
(2) take a turn for the better: clinical symptoms partly disappears or obviously alleviates;
(3) invalid: clinical symptoms does not have improvement or increases the weight of.
Five, therapeutic effect: in this clinical observation case, take medicine 1-6 the course of treatment, cure 42 examples, 19 examples that take a turn for the better, invalid 3 examples.Toxic and side effects does not take place during the treatment.
Six, model case:
Case 1:
In certain, the woman, 30 years old, operating pressure was big, did not like food, food back distension, stomach has burning sensation, and is especially obvious before the prescription on individual diagnosis.Take 2 courses of treatment of medicament of Chinese medicine composition preparation of the present invention, symptom disappears substantially; Continue to strengthen 1 course of treatment, the healing that all disappears of all symptoms.
Case 2:
Beam, man, 62 years old.Private prosecution during prescription on individual diagnosis: stomach distending pain after meal, have heartburn, acid regurgitation sense, constipation.Take 2 courses of treatment of medicament of Chinese medicine composition preparation of the present invention, abdominal distention, gastral cavilty distension alleviate slightly behind the conscious medicine, heartburn, acid regurgitation do not occur, the arteries and veins slight force; 1 course of treatment of continuous clothes, abdominal distention, gastral cavilty distension are not obvious; Diet increases, and is comfortable in the stomach of food back; Stool does not do not rare once a day; No singultus, heartburn, acid regurgitation symptom; Consolidate again and take 1 course of treatment, transference cure, appetite increases, and is energetic.