CN102861292B - Medicament for treating esophageal cancer and preparation method thereof - Google Patents
Medicament for treating esophageal cancer and preparation method thereof Download PDFInfo
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- CN102861292B CN102861292B CN2012103461566A CN201210346156A CN102861292B CN 102861292 B CN102861292 B CN 102861292B CN 2012103461566 A CN2012103461566 A CN 2012103461566A CN 201210346156 A CN201210346156 A CN 201210346156A CN 102861292 B CN102861292 B CN 102861292B
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Abstract
The invention discloses a medicament for treating esophageal cancer and a preparation method thereof. The medicament comprises the following raw materials in parts by weight: 10 to 30g of leech, 10 to 30g of rosewood heart wood, 20 to 40g of garden balsam seed, 30 to 50g of astragalus mongholicus, 30 to 50g of coix seed, 30 to 50g of poria, 10 to 30g of red peony root, 10 to 30g of whitepeony root, 20 to 40g of Chinese sage herb, 10 to 30g of manyleaf paris rhizome, 10 to 30g of angelica root, 10 to 30g of bitter orange, 20 to 60g of kelp, 10 to 60g of seaweed, 20 to 40g of curcuma zedoary, 5 to 15g of prepared nux vomica, 10 to 30g of scorpion, 10 to 30g of stir-baked pangolin, 10 to 30g of realgar, 10 to 30g of nidus vespae, 10 to 30g of stiff silkworm, 10 to 30g of ginseng, 20 to 40g of areca-nut and 10 to 30g of combined spicebush root. The medicament has the efficacies of activating blood circulation to remove stasis, removing stagnation and eliminating stasis, combating poison with poison, and treating diseases and killing cancer, does not have side effect to a human body, can be used for treating both primary and secondary diseases, is safe and practical, and has good treatment effect on upper, middle and lower esophageal cancers.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of the esophageal carcinoma and preparation method thereof, be specifically related to a kind of Chinese medicinal aqua for the treatment of the esophageal carcinoma.
Background technology
The esophageal carcinoma is that the throat esophagus has foreign body sensation, if feelings will is easypro, and disorder of QI movement, the retention of phlegm and dampness in bulk is sent out and is the esophageal carcinoma, and then dysphagia in various degree occurs, last critical people's life, global sickness rate journey ascendant trend over advancing year, China area is the district occurred frequently, the early stage resection operation of the esophageal carcinoma, and the chemotherapy of postoperative, also can cause body tissue damage and QI and blood loss to the patient, the patient is had a delicate constitution, and easily cause the recurrence of the esophageal carcinoma, the diffusion transfer of cancerous cell.
Summary of the invention
The object of the present invention is to provide a kind of medicine for the treatment of the esophageal carcinoma and preparation method thereof, medicine of the present invention has blood circulation promoting and blood stasis dispelling, the removing food stagnancy eliminating stagnation, treating the poisonous disease with poisonous drugs ， Po Disorder kills the effect of cancer, and to the people without negative interaction, treating both the principal and secondary aspects of a disease, safe and feasible is to three sections esophageal carcinoma of upper, middle and lower good therapeutic effect all.
The present invention adopts following technical scheme:
the medicine of the treatment esophageal carcinoma, the weight portion of its constitutive material is: Hirudo 10-30 gram, Lignum Dalbergiae Odoriferae 10-30 gram, Semen Impatientis 20-40 gram, Radix Astragali 30-50 gram, Semen Coicis 30-50 gram, Poria 30-50 gram, Radix Paeoniae Rubra 10-30 gram, Radix Paeoniae Alba 10-30 gram, Herba Salviae Chinensis 20-40 gram, Rhizoma Paridis 10-30 gram, Radix Angelicae Dahuricae 10-30 gram, Fructus Aurantii 10-30 gram, Thallus Laminariae (Thallus Eckloniae) 20-60 gram, Sargassum 10-60 gram, Rhizoma Curcumae 20-40 gram, Semen Strychni(processed) 5-15 gram, Scorpio 10-30 gram, stir-baked SQUAMA MANITIS 10-30 gram, Realgar 10-30 gram, Nidus Vespae 10-30 gram, Bombyx Batryticatus 10-30 gram, Radix Ginseng 10-30 gram, Semen Arecae 20-40 gram and Radix Linderae 10-30 gram.
The medicine of the treatment esophageal carcinoma, the weight portion of its constitutive material is: Hirudo 20 grams, Lignum Dalbergiae Odoriferae 20 grams, Semen Impatientis 30 grams, the Radix Astragali 40 grams, Semen Coicis 40 grams, Poria 40 grams, Radix Paeoniae Rubra 20 grams, the Radix Paeoniae Alba 20 grams, Herba Salviae Chinensis 30 grams, Rhizoma Paridis 20 grams, the Radix Angelicae Dahuricae 20 grams, Fructus Aurantii 20 grams, Thallus Laminariae (Thallus Eckloniae) 40 grams, Sargassum 40 grams, Rhizoma Curcumae 30 grams, Semen Strychni(processed) 10 grams, Scorpio 20 grams, stir-baked SQUAMA MANITIS 20 grams, Realgar 20 grams, Nidus Vespae 20 grams, Bombyx Batryticatus 20 grams, Radix Ginseng 20 grams, Semen Arecae 30 grams and the Radix Linderae 20 grams.
The preparation method of the medicine of the treatment esophageal carcinoma comprises the following steps:
Weight portion by constitutive material takes each raw material, then adds to decoct medicinal herbs vessel, injects 2 kilograms, clear water, soak after 90 minutes, slow fire is endured it, decocts medicinal herbs routinely three times, convert one and endure altogether, little fire is fried in shallow oil to get medicinal liquid approximately after 300ml slowly, injects the 100ml refined honey, slow fire is endured, twist while enduring and mix, get approximately 300ml of medicinal liquid, cold fixed, enter bottle closure, storage.
The pharmacological action of various crude drug in this formula:
Hirudo: salty in the mouth, hardship, property is flat poisonous, saltyly can walk blood system, the eliminating stagnation softening the hard mass, bitter kind falling let out, and has removing blood stasis to lead to the stasis of blood, and the effect of stimulating the menstrual flow and closing is applicable to blood stasis and gathers, in bulk in abdomen, menstruation is obstructed waits disease, and can be with tire, and the traumatic injury blood stasis is had a pain, all can cure, normal and pink with controlling that blood stasis Jing Bi WEIJIA is gathered and traumatic stasis swells and ache etc., Radix Angelicae Sinensis, Rhizoma Curcumae etc. match, if the person of having a delicate constitution will add the Radix Astragali, Radix Codonopsis, Radix Polygoni Multiflori Preparata etc., the product that fill blood are with righting gas.Modern serious disease research: fresh Hirudo has Blood clotting, also has blood fat reducing to promote absorption of hematoma, reduces serum urea nitrogen and flesh infantile malnutrition, the effects such as inhibition tumor cell and termination of pregnancy.
Lignum Dalbergiae Odoriferae: acrid in the mouth, warm in nature, the hemostasis blood stasis expelling is warded off the evil sending down the abnormal ascending QI, and stomachache is all removed, but can stop blooding and clots absorbing.Gas fragrance is kind wards off dirty evil, matter Beijing South Maxpower Technology Co. Ltd sending down the abnormal ascending QI, and therefore every foul internal resistance, vomiting stomachache, and the diseases such as the sternal rib pain of qi depression to blood stasis and traumatic hemorrhage all can be used.[modern study] this product contains dalbergin, and nor-Huang is arrogated to oneself element, and isodalbergin etc., dalbergin, nor-Huang are arrogated to oneself element all faint anticoagulation, can also increase the analgesia of coronary flow decreased heart rate and anti-frightened effect.
Semen Impatientis: be the Flos Impatientis mature seed, drying is used as medicine.[meridian distribution of property and flavor] bitter in the mouth, warm in nature slightly poisonous, return lung, Liver Channel, [function with cure mainly] relieves internal heat anticancer, loose abdominal mass detumescence, the removing blood stasis softening the hard mass, removing food stagnancy, Yong Yu mass in the abdomen mass in the abdomen, amenorrhea, dysphagic.The clinical difficult menstruation that is used for the treatment of, difficult labour, placenta retention, children's's mass in the abdomen, the food of choking, throat moth, the kidney disease, the testis traumatic pain is with the corresponding medicine treatment esophageal carcinoma of associating with, gastric cancer, hepatocarcinoma, pulmonary carcinoma etc.
The Radix Astragali: sweet in the mouth, warm in nature, return the spleen lung meridian, tonifying Qi and lifting yang, hemopoietic is capable stagnant, strengthening superficial resistance to stop perspiration, holder skin ulcer granulation promoting, inducing diuresis to remove edema.This product is the key medicine of tonifying Qi and lifting yang.Deficiency of defensive qi flesh table is not solid, can cause continuous perspiration, and this product can the tonifying the lung gas-solid be defended gas, therefore be usually used in the spontaneous perspiration of exterior deficiency; If the night sweat due to yin deficiency person also can use.Gas fills blood Sheng, so can enrich blood again, treatment is unable because of the vim and vigour virtual loss, the ulcer sores of expelling pus and toxin by strengthening QI or difficult closing in granulation promoting etc.This product also has the effect of gas and inducing diuresis to remove edema in elevate a turnable ladder.This product is used for the treatment of deficiency of both the splenic and pulmonary QI or all cards of sinking of QI of middle-JIAO, belong to after being ill deficiency of vital energy and physically weak can with the same use of Radix Ginseng, in genus a little less than the deficiency of vital energy, anorexia and loose stool or have loose bowels can be with Rhizoma Atractylodis Macrocephalae Poria Radix Glycyrrhizae with using; Belong to Qi and blood deficiency, can with Radix Angelicae Sinensis, the same use of Radix Rehmanniae Preparata, belong to deficiency of vital energy sun and decline, the fear of cold hyperhidrosis, can with the same use of drugs for dispelling internal cold such as Radix Aconiti Lateralis Preparata, belong to sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, uterine prolapse, normal with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, process Radix Glycyrrhizae, give birth to numb, Radix Bupleuri and be equal to use; Belong to the deficiency of vital energy and can not take the photograph the having blood in stool of blood, metrorrhagia, normal and Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Arillus Longan, Semen Ziziphi Spinosae is equal to use.Control the exterior deficiency spontaneous perspiration, can with Fructus Tritici Levis, Concha Ostreae, Radix Ephedrae is equal to use; Night sweat due to yin deficiency many is equal to use with the Radix Rehmanniae, Radix Rehmanniae Preparata, Cortex Phellodendri, and with controlling insufficiency of vital energy and blood, carbuncle is not burst or routedly do not held back for a long time, and how and Radix Angelicae Sinensis, Rhizoma Chuanxiong, Squama Manis, Spina Gleditsiae, or Radix Rehmanniae Preparata Radix Angelicae Sinensis, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae Cortex Cinnamomi be equal to use, with saturating pus holder skin ulcer, promoting tissue regeneration and wound healing.Lose profit with controlling QI and blood, the edema oliguria, many and Radix Stephaniae Tetrandrae, the Rhizoma Atractylodis Macrocephalae, Poria are equal to use, to strengthen the merit of spleen invigorating diarrhea due to disorder of QI urine detumescence.Note when using this product; The temperature rise of this product character can help fire, again can invigorating QI to consolidate the body surface resistance, therefore pathogenic factor in the exterior is arranged outward, in have stagnant, the QI excess fullness in the chest, overabundance of YANG leading to deficiency of YIN, heat in the upper and cold in the lower, the many anger of liver-yang hyperactivity and carbuncle from the beginning of or burst after victor on pyretic toxicity, all should not take.[modern study] this product mainly contains infantile malnutrition class, polysaccharide, and aminoacid and trace element have the enhancing human body immunity function, diuresis, defying age, protect the liver, the effect such as blood pressure lowering; Can strengthen myocardial contraction, estrogenic promoting action and antibacterial action in addition more widely.Astragalus polysaccharides has the mice of raising stress ability and strengthens immunologic function, regulates blood sugar content, and the protection cardiovascular system accelerates to suffer the effects such as reparation of radiation damage human body.
Semen Coicis: sweet in the mouth, light, flat being slightly cold, return spleen, stomach, lung meridian.Lightly can ooze profit, sweet and invigorating middle warmer, the heat clearing away that is slightly cold has strengthening the spleen and tonifying the lung, diuretic dehumidifying, the effect of clearing away heat and discharging pus.Main dispelling the wind and dampness pathogens arthralgia pain, joint contracture, and the edema of water-damp retention are had loose bowels, oliguria, and control " consumptive lung disease " of cough vomiting bloody pus.In addition, can dehumidify because of kind, pathogenic factor is separated from urine, also can control hygropyrexia or fever disease in summer from the beginning of the diseases such as gastral cavity painful abdominal mass heavy sensation of the body.Be mainly used in treating all diseases of stagnation of dampness due to deficiency of the spleen, have wetly as insufficiency of the spleen, lack of appetite is had loose bowels, and edema beriberi etc. can be equal to use in Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Poria, Rhizoma Dioscoreae.Arthralgia chiefly caused by damp pathogen is normal is equal to use with Rhizoma Atractylodis, Cortex Phellodendri, Radix Achyranthis Bidentatae with controlling, with controlling lung abscess, can with Radix Scutellariae, Semen Persicae, Semen Benincasae use together.Control acute appendicitis with Radix Aconiti Lateralis Preparata, Herba Patriniae compatibility.[modern study] this product mainly contains Semen Coicis oil, coixenolide, fatty oil, aminoacid etc.Semen Coicis oil stops the effect of reduction striped muscle contracture, and the uterus is excitation.And have that heat clearing away is calm, analgesic activity.Decoct has certain inhibitory action to cancerous cell.
Poria: i.e. Poria, sweet in the mouth, light, flat, GUIXIN, lung, kidney channel.Sweet gentle slow, light and ooze profit, the promoting diuresis to eliminate damp pathogen effect is arranged, therefore make the wet clump of the water urethra excretion that rests in body can control that expectorant is not changed and the card such as dysuria, this product is divided two kinds of red blood, the Poria saliva of being good at reducing phlegm, red Poria is long diuresis waterway.This product promoting diuresis to eliminate damp pathogen also is usually used in causing because water is wet in addition has loose bowels and diseases caused by retention of fluid is insulted the cards such as palpitation with fear insomnia that the heart causes.Clinical practice: the wet diseases such as edema distension dysuria of stagnating are normal with harnessing the river is equal to use with Zhu Siberian cocklebur, the Rhizoma Atractylodis Macrocephalae, Rhizoma Alismatis, Ramulus Cinnamomi, with the merit of reinforcement diuretic.With the refreshing spleen lack of appetite of controlling spleen insufficiency, abdominal swelling, the diseases such as diarrhea, normal be equal to use with Radix Codonopsis, Radix Angelicae Sinensis, Arillus Longan, Semen Ziziphi Spinosae, belong to deficiency of heart-QI, or not friendship of gains in depth of comprehension person, again often and Radix Ginseng, Dens Draconis and Radix Polygalae, Rhizoma Acori Graminei, Cinnabaris are equal to use.[modern study] this product contains pachyman, pachymic acid, protein, fat, lecithin choline, histamine, ergosterol etc., has diuresis, the calm blood glucose that reduces, the effect of antitumor and increase immunologic function.
Radix Paeoniae Rubra: [meridian distribution of property and flavor] hardship, be slightly cold, return Liver Channel.Radix Paeoniae Rubra acid is cold can rush down and can fall apart, and removing blood stasis stimulates the menstrual flow.Kind divide hot and suffocatingly except nutrient blood, and the stasis of blood in the blood that can fall apart has the purge heat effect of dissipating blood stasis of removing heat from blood, is usually used in all heat in blood, the disease of blood stasis, thus title " can purge heat loose " its bitter cold removing heat from blood blood stasis removing, the carbuncle that also can fall apart, removing fire from the liver removing blood stasis with potent drugs blood stimulates the menstrual flow and closes.Be applicable to pyretic toxicity carbuncle and the not all right amenorrhea of women's blood stasis, and the various pain that cause because of blood retardance, but to puerperal congested weak patient should not use, this product clearing away liver-fire eliminating stasis to stop pain etc. in addition.[modern study] this product contains paeoniflorin, paeonol, paeoniflorin, benzoic acid, tannin, volatilization wet goods, and the blood pressure lowering of sedation and analgesia convulsion, infection, antiulcer are arranged, and antibacterial, anti-blood is fastened formation, and anticoagulant increases the effects such as coronary flow.Attention cold in blood amenorrhea should not be used.Anti-Rhizoma et radix veratri (Radix Rhizoma Veratri) is avoided with using.
The Radix Paeoniae Alba: [meridian distribution of property and flavor] is sweet, bitter, sour, is slightly cold, and returns liver, spleen channel.Radix Paeoniae Alba sweet in the mouth, bitter, cold nature, sweet benefit acid is received, and the effect of convergence and replenishing YIN and blood is arranged, liver-yin is held back in this product acid, suppressing liver-YANG, the easing the affected liver of enriching blood, relieving spasm to stop pain, so can stop having loose bowels of excessive wood over-restricting earth, dysentery, stomachache, and deficiency of YIN anemia and the caused costa sternales epigastric pain of excess of liver-YANG, spasm of the limbs pain, menoxenia etc.Gallbladder belongs to can not using of deficiency and coldness, and the sweet sour yin fluid astringing of this product in addition also has the merit of hidroschesis, is usually used in spontaneous perspiration or the night sweat due to yin deficiency person of exterior deficiency aversion to wind, during use when noting: the decline disease of deficiency and coldness of sun should not be used separately, and anti-Rhizoma et radix veratri (Radix Rhizoma Veratri) is avoided with using.[modern study] this product Main Ingredients and Appearance is paeoniflorin, separately also contains tannin, volatile oil, fat, paeonol and triterpenoid compound etc.Contained paeoniflorin has spasmolysis preferably to rat stomach, intestinal, uterine smooth muscle, and certain infection is arranged, and is antibacterial, calmness, and analgesia, convulsion, the effects such as blood pressure lowering blood vessel dilating, and strengthen the myocardial nutritional flow amount.
Herba Salviae Chinensis: be the herb of labiate Salvia chinensis, tap herb florescence, using fresh herb or dry, branch in Jiangsu, the ground such as peace little, Jiangxi, Hubei, Hunan, Guangdong, Guangxi, Sichuan, Yunnan.Have several: Herba Salviae Chinensis, tendencies flower, little Radix Salviae Miltiorrhizae, below the moon red, official post is careless, black flour wind, Rsdix Wisterinae Venustae, stone great river, mountain seam are taken, Zi Danhua, Arisaema balansae Engl. ginseng, four Herba Apii graveolentis, HUOXUECAO.[meridian distribution of property and flavor] acrid in the mouth, hardship, cold nature is returned liver, spleen channel.Function cures mainly; Blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, mass dissipating and swelling eliminating.The treatment menoxenia, dysmenorrhea, amenorrhea, metrorrhagia is had blood in stool, jaundice due to damp-heat, toxic-heat and blood stasis drenches pain, leukorrhagia, rheumatic ostalgia, the cellulitis pestilence, the carbuncle sore acute mastitis, zona shingles, leprosy, the traumatic injury wound is swollen, mass in the abdomen, cancerous protuberance.
Rhizoma Paridis: [meridian distribution of property and flavor] hardship, be slightly cold, slightly poisonous, return Liver Channel, [efficacy of drugs] heat-clearing and toxic substances removing, subduing swelling and relieving pain, cool liver arresting convulsion.The Rhizoma Paridis bitter in the mouth, cold nature, slightly poisonous, hardship is let out to fall, and the heat clearing away of cold energy enters again Liver Channel, and heat-clearing and toxic substances removing is arranged, reducing swelling and alleviating pain, the effect of dispelling wind and relieving convulsion can be used for the furuncle swollen ulcer drug, and snake bite and insect sting is also controlled infantile convulsion, tic of the limbs, and epileptics.[modern study] this product contains Rhizoma Paridis glycosides, dioscin, tannin and aminoacid etc.Have broad-spectrum antibiotic, venom is calm, analgesia, antitussive and antiasthmatic, the effects such as hemostasis and antitumor.
The Radix Angelicae Dahuricae: [meridian distribution of property and flavor] is hot, warm.Attach to the lung and stomach meridians.[efficacy of drugs] the loose wind that induces sweat, understand things pain-stopping, dampness leukorrhagia stopping, detumescence and apocenosis.Radix Angelicae Dahuricae acrid in the mouth, warm in nature, hot warm-dryness syndrome is loose, and fragrance is walked to alter, reaches on its property, the cold expelling that can induce sweat, wind-expelling pain-stopping, a surname's clearing the nasal passage, the kind wind and cold of controlling is invaded the neck that Yangming Channel causes and is had a pain and nasosinusitis headache, is the anemofrigid cold common medicine, the common medicine that acute mastitis such as swells and ache at the disease.[modern study] this product contains Radix Angelicae Dahuricae element, Radix Angelicae Dahuricae ether, angelicotoxin etc., stimulating central nervous system in a small amount, can cause tonic spasm in a large number, continue with general paralysis, infection is arranged, ease pain relieving convulsion, spasmolytic, antitumaous effect can suppress scratching nervous system in due to venom, and certain inhibitory action is arranged.
Fructus Aurantii: Fructus Aurantii is slightly cold, the fast wide intestinal of gas, and depressed in the heart, distension may be tasted.Fructus Aurantii bitter in the mouth, suffering are slightly cold.Pungent drugs can disperse and bitter drugs can descend is longer than regulating the flow of QI to ease the stomach, and relieving distension is except painful abdominal mass, and is main same with controlling the breast abdomen stagnation of QI, the disease of feeling of fullness distending pain.Clinical practice; With the strongly fragrant stagnation of QI for the treatment of the liver, sternal rib pain, normal and Radix Bupleuri, Rhizoma Cyperi, Radix Paeoniae, Rhizoma Chuanxiong, Radix Glycyrrhizae are used together.[modern study] this product mainly contains volatile oil, can reconcile gastrointestinal function and choleretic effect is arranged.
Thallus Laminariae (Thallus Eckloniae): salty-cold, softening the hard mass heat clearing away, Ying Liu mass in the abdomen tuberculous lymphadenitis.The Thallus Laminariae (Thallus Eckloniae) salty in the mouth is cold in nature, salty kind softening the hard mass, and expectorant knot, loose goiter effect are arranged, and can control the disease of goiter and tuberculous lymphadenitis, and the mass in the abdomen that can also disappear is in addition controlled lump pain and painful and swollen testis under rib, the effect of hard masses softening and resolving is arranged, clinical practice; With controlling goiter, often breathe out shell, the same use of Medulla Tetrapanacis with Sargassum, sea, be smalls altogether, water is general is the ball clothes, treats scrofula expectorant and resists, and often and Radix Scrophulariae, Spica Prunellae, living maggot oyster, the same use of Bombyx Batryticatus, grinds into powder and is ball, Radix Ranunculi Ternati is fried in shallow oil soup and takes.Lump pain under rib is controlled in this external, often joins Concha Ostreae, Radix Salviae Miltiorrhizae, rhizoma sparganic, Rhizoma Curcumae, Radix Angelicae Sinensis, Carapax Trionycis, the same use of Semen Persicae, controls painful and swollen testis and works as in Semen Litchi again, and Semen Citri Reticulatae is with using.
Sargassum: Sargassum is salty-cold, the wart that the disappears tumor of faling apart, and except bursting Disorder, diuretic is logical to be closed, Sargassum bitter in the mouth, salty, cold in nature, resolving phlegm and softening hard masses is arranged, the effect of clearing away heat and promoting diuresis, the goiter that can disappear fall apart scrofula, except distension, abdominal mass disappears, also control painful and swollen testis, in addition, also have the effect of diuresis diuresis.Clinical practice: with controlling scrofula tuberculosis, can be the end altogether with Bombyx Batryticatus, it be ball that Fructus Armeniacae Mume is fried in shallow oil soup, as it is swollen to control the scrofula knot, can with Thallus Laminariae (Thallus Eckloniae), the same use of the medicines such as sea clam, bosom and Spica Prunellae, Fructus Forsythiae, the compatibilities such as Radix Scrophulariae, but with controlling 5 uses mutually of the diuretic medicines such as beriberi edema and edema Rhizoma Alismatis, anti-Radix Glycyrrhizae.[modern study] this product contains algin acid, mannitol, potassium iodine etc., and the thyromegaly that iodine deficiency is caused has therapeutical effect; First shape hyperfunctioning basal metabolic rate is increased temporary transient inhibitory action, and algin acid, sulfuric acid ester can reduce serum cholesterol, alleviate atherosclerosis, and lipidemia also has the anticoagulant antithrombotic, improves microcirculation, blood pressure lowering, bacteriostasis.
Rhizoma Curcumae: the bitter temperature of Rhizoma Curcumae, kind broken mass beside the umbilicus, the pain relieving repercussive stimulates the menstrual flow the most suitable.Rhizoma Curcumae, bitter in the mouth, warm in nature, the effect of circulation of qi promoting dissipating blood stasis blood and digestion food stagnation is arranged, be good at controlling in abdomen not slake blood stasis caking of food stagnation, also can be used for women's amenorrhea obstructed, the stomachache that blood stasis is not all right can play the effect of inducing menstruation to relieve menalgia.Clinical practice; With controlling qi depression to blood stasis Suo Zhi lumps in the chest and abdomen amenorrhea due to stagnation of blood, puerperal, blood stasis blocked, and the normal and same use of rhizoma sparganic is modern with controlling ectopic pregnancy, hepatosplenomegaly, also normal and rhizoma sparganic is cut the principal agent of heavily fortified point altogether for removing blood stasis, with controlling stagnation of QI due to dyspepsia, chest and abdomen swelling and pain is made good use of than rhizoma sparganic, and normal and Pericarpium Citri Reticulatae Viride, Semen Arecae, Semen Pharbitidis are equal to use.[modern study] this product contains volatile oil, wherein is mainly curzerenone, curzerene, curcumins etc. have anticancerly, and antithrombotic forms anticoagulant, infection, antiulcer, excited gastrointestinal smooth muscle, the specific immune function effect of the antibacterial and enhancing body of antiearly pregnancy.
Semen Strychni: [meridian distribution of property and flavor] hardship, cold, very toxic, return liver, spleen channel.[efficacy of drugs] activating collaterals and eliminating stagnation, subduing swelling and relieving pain.Semen Strychni is named again kind not Trionyx sinensis Wiegmann, and bitter in the mouth is cold in nature, very toxic, and the malicious the meridian dredging of detumescence is arranged, and the effect of pain relieving can be used for laryngopharynx swelling and pain, swollen ulcer drug, and the scrofula malignant boil is with the muscle arteries and veins contracture that causes through rheumatism, paralysis and numbness etc.The contained principal goods alkali of [modern study] Semen Strychni, absorb very soon after strychnine is oral and work, the reflection function of at first excited spinal cord, respiratory center and vasomotor center in next excited spinal cord, and the function of raising sensorium, heavy dose causes convulsions, and stronger antitussive effect is arranged and eliminate the phlegm, anti-asthmatic action also has inhibitory action to some cell and fungus.
Scorpio: [meridian distribution of property and flavor] is sweet, hot, and be flat, poisonous, returns Liver Channel, efficacy of drugs: wind-repellent itching-relieving, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain, Scorpio sweet in the mouth, suffering, flat, property is flat poisonous, the expectorant of dispeling the wind, the effect that spasmolytic is twitched is apt to control apoplexy and is caused facial hemiparalysis, and hemiplegia and infantile convulsion are demonstrate,proved bitterly, tic of the limbs etc., this product are separated sore, subduing inflammation in addition, the effect of loose expectorant knot can control that hemorrhoid or skin ulcer are swollen itches, all diseases of tuberculous lymphadenitis.This product energy removing obstruction in the collateral to relieve pain is good at treating the diseases such as migraine and general headache, rheumatic arthralgia, and use and note: poisonous, deficiency syndrome and anemia of pregnant woman are cautious use of.[modern study] this product contains scorpion venom, trimethylamine, SHENGHUANG acid, palmitic acid, stearic acid, cholesterol etc., has convulsion anti-top epilepsy, blood pressure lowering, calmness, antithrombotic to form, anticoagulant, the effect such as anticancer, and the main harm of scorpion venom is to make respiratory paralysis.
Squama Manis: Squama Manis poison, hemorrhoid addiction malignant boil, the mammary abscess carbuncle that swells, powdered medicine ' Tongluosan ' wind.The Squama Manis salty in the mouth, cold nature, poisonous, its property is apt to away alter, and merit specially row is loose, interior logical internal organs, the meridians of passing through inside have the removing blood stasis with potent drugs detumescence, evacuation of pus, the effect of lower milk.With controlling the swollen carbuncle of hemorrhoid and skin sore, and it is obstructed to control mammary gland, acute mastitis etc.All carbuncle can make dissipation: when becoming pus, can make it early to burst, can also treat limb spasm or the tetanic pain of anemofrigid-damp arthralgia herein and must not stretch disease in the wrong.Use and note: the anemia of pregnant woman is cautious use of, and carbuncle routed person be cautious use of.[modern study] this product has the prolongation clotting time, reduces blood viscosity, blood vessel dilating, hemocytes increasing etc.
Realgar: bitter, hot, temperature, poisonous, return liver, large intestine channel, effect: the detoxifcation parasite killing, dampness is removed expectorant.The Realgar bitter in the mouth is hot, and the Serpentis a poisonous snake mentioned in ancient books is more controlled in the detoxifcation that exorcises evil spirits, the acute throat trouble polyp, function detoxifcation parasite killing can be controlled ulcer sore pain, poison, scabies, eczema, snake bite and insect sting, this product again can expectorants, can control laryngopharynx swelling and pain Fu inhale rapid, the acute throat trouble of Tan Duo Yong plug, but message meat in addition, use and note: be not taken by pregnant women, one must guard against fire forges, and decomposes after forging to be oxidized to arsenic trioxide, severe toxicity is arranged, and Realgar can absorb from Leatherwear, therefore local topical can not large tracts of land be smeared.[modern study] this product Containing Sulfur arsenic, and contain other a small amount of heavy metallic salts to the various skin fungus, the Staphylococcus aureus mattress, Bacillus proteus, bacillus pyocyaneus have the not inhibitory action of same-action, and schistosomicide is arranged, protozoon and antitumor action.
Nidus Vespae: [meridian distribution of property and flavor] is sweet flat slightly poisonous, returns Liver Channel.Efficacy of drugs: the counteracting toxic substances worm of stopping, wind-expelling pain-stopping, Nidus Vespae salty in the mouth, hardship, property is flat, and is poisonous, the effect of wind dispelling detoxifcation parasite killing is arranged, can control the infantile convulsion epilepsy, tetany, decayed tooth is had a pain and carbuncle sore tumefacting virus, scrofula, the carbuncle of breast pain etc. that swells and ache, clinical practice: can be alone or join Fructus Zanthoxyli with controlling caries pain, Herba Asari is fried in shallow oil the water rinsing the mouth or is ground foam wiping tooth with Scorpio.With controlling the rubella pruritus, available this product is fried in shallow oil that juice dissolves in the Matrii Sulfas Exsiccatus external application or is that foam wine is taken after mixing with liquid with Periostracum Cicadae, with controlling a upper skin ulcer tinea, can wash by alone liquid medicine, or grinds foam Adeps Sus domestica and transfer and be coated with.With controlling scrofula, can with Olibanum, the Bulbus Fritillariae Uninbracteatae Spica Prunellae is equal to use, with controlling migratory arthralgia, can with single clove garlic, Pulvis Fumi Carbonisatus is smash deposited affected part.[modern study] this product master contains Cera Flava and resin, contains again poisonous Nidus Vespae oil.Its alcohol, ether and acetone immerse thing all the effect that promotes blood coagulation: infection, analgesia, diuresis, heart tonifying, blood pressure lowering, ascarifuge cestode, the effect such as anticancer are arranged.
Bombyx Batryticatus: [meridian distribution of property and flavor] is salty, and suffering is slightly cold, and returns liver, lung meridian.Efficacy of drugs: endogenous wind stopping relieving convulsion, wind-expelling pain-stopping, dissipating phlegm and resolving masses.Can control tic of the limbs and the headache due to pathogenic wind-heat of infantile convulsion and epilepsy syndrome, toothache, ophthalmalgia, laryngopharynx swelling and pain etc.Can dehumidify in addition and reduce phlegm, the sore that disappears is usually used in scrofula scrofula due to accumulation of phlegm and skin eczema erysipelas etc., grinds external application into powder, all skin ulcer cicatrixs of going out.[modern study] this product contains protein, fat, ash, ammonium oxalate etc., and certain syngignoscism is arranged, and convulsion anticoagulant blood sugar lowering is arranged in addition, and the effect that stimulates adrenocortical hormone is arranged.
Radix Ginseng: [meridian distribution of property and flavor] is sweet, little hardship, tepor.Return spleen, lung meridian.efficacy of drugs: strongly invigorating primordial QI, the supplementing the brain strengthening the spleen, the nourishing blood to tranquillize the mind that promotes the production of body fluid increases intelligence, the Radix Ginseng sweet in the mouth, little hardship, warm in nature, Gan Wenzhu mends, kind tonification vigour, vigour is former in kidney essense, change the gas of the Yuanyang Kidney-Yin of giving birth to the whole body, to promote swollen internal organs function, the power of QI-blood circulation and nutrition whole body, the pretty gas that replenishes of this product, supplementing QI to prevent collapse, it is the first key medicine of the collapse asthenia internal injury for the treatment of, can save serious disease prolonged illness, and the large vomiting and diarrhoea reason such as lose blood greatly, due to vigour dissipate, the deficiency syndrome that faint pulse is wanted to take off, can also supply QI of five ZANG-organs, treat all syndrome of deficiency of QI, as insufficiency of heart-QI, cardiopalmus is not mended and is slept, the deficiency of spleen-QI cold extremities of having loose bowels, insufficiency of lung-QI, the asthma breath is short, the deficiency of liver-QI palpitation with fear is not peaceful, the soft grade of deficiency of kidney-QI weak bone flaccidity disease.Primordial Qi fills that taste are not empty, and transporting is normal, can the little cloth body fluid of semen deposition, therefore this product has the effect of promoting the production of body fluid and only drinking, be used for the disease that internal injury is quenched one's thirst, its strongly invigorating primordial QI, the gas of the tonifying five ZANG-organs of holding concurrently is changed and is given birth to whole body QI and blood, external enwergy nourishing the stomach gas, interior accent nutrient blood, all insufficiency of vital energy and blood diseases, all can use, in addition, this product strongly invigorating primordial QI, again can nourishing qi to stop, tonifying YIN is supporing yang, also with the hemorrhage of controlling QI failing to control blood, though vigour is the sexual impotence card of decline of the fire from the gate of life not, in clinical prescription, this product and the same use of eliminating evil medicine, can play strengthening vital QI to eliminate pathogenic factors.Note during use: Rhizoma et radix veratri (Radix Rhizoma Veratri), Oletum Trogopterori, Fructus Gleditsia is avoided same use, and deficiency of YIN sun is anti-, and the osteopyrexia and fever cough is spitted blood, and lung has excess-heat, or the stagnant cough of mental disorder heap soil or fertilizer over and around the roots, and liver-fire rises, and in all fire stagnation, the disease of reality is all avoided clothes.[modern study] Radix Ginseng has the effect of " adaptogen " sample, mainly contain multiple panaquilon, the neururgic excitement of high energy and process of inhibition all there are potentiation, shock, resisting fatigue, radioprotective, antiallergic, diuresis, antitumaous effect are arranged, can excitedly strengthen gonad function, the promotion hormone-like effect is arranged, can reduce blood glucose in addition, promote protein, the biosynthesis of DNA, RNA, reconcile cholesterol metabolism, promote the function of hemopoietic system.
Semen Arecae: Semen Arecae is hot, warm, and the removing blood stasis parasite killing eliminates the phlegm and relieves oedema or abdominal distension through diuresis or purgation, specially except rear heavy, and Semen Arecae acrid in the mouth, hardship, warm in nature, hot loose hardship is fallen, and its property is descending, and its decline circulation of qi promoting strength is larger, and the effect of driving away Enterozoa is arranged, and claims the dispelling the stagnated QI parasite killing.In addition, its hot loose hardship is let out, promoting the circulation of QI to induce diuresis, and removing food stagnancy, for staying distension and fullness of the chest and abdomen, the edema that causes because of the expectorant water retention, and the dysentery that does not disappear and cause because of food stagnation, stomachache, the diseases such as tenesmus all can be treated.Use and note, insufficiency of the spleen loose stool or insufficiency of the spleen sagging person should not take.[modern study] this product contains alkaloid, is mainly arecoline, and the effect of anthelmintic parasite killing is arranged, and the effect of the choline of plan is arranged, excitement, and cholinoceptor promotes the saliva sweat gland secretion, increases enterokinesia, and decreased heart rate reduces blood pressure, and eye drip can make contracted pupil.
The Radix Linderae: the Radix Linderae is hot, temperature, trusted subordinate's distending pain; the sliding number of urine, and is pleasant general, Radix Linderae acrid in the mouth; warm in nature, and Xin Kaiwentong declares smooth mechanism of qi; the effect except cold pleasant pain relieving is arranged, and kind cold strongly fragrant QI rising in reverse order, the chest and abdomen swelling and pain; QI rising in reverse order dyspnea with rapid respiration controlled; colic of cold type stomachache, and the bladder sliding sharp frequency of urine that has cold air to cause are the common drugs of pleasant cold expelling.This product function circulation of qi promoting dispersing cold for relieving pain also is applicable to few abdomen connects and testis is had a pain " hernia ", and the women's Qi stagnation blood clotting, few abdomen disease such as have a pain.Note during use; Deficiency of both QI and blood and have the interior-heat person is cautious use of.Modern [research] this product contains alkaloid and volatile oil, and gastrointestinal smooth muscle is had two-way mediation function excited and that suppress, has short secretion aid digestion, and excited cerebral cortex promotes the respiratory stimulant cardiac muscle, accelerates blood circulation and effect, and antibacterial action is arranged.Above all medicines produce common coordinative role from bringing into play characteristic, to the early stage not yet esophageal carcinoma of metastasis cancer cell, respond well, the food labor that shifts the diffusion cancerous cell is sought cancer, pain is arranged, cough, unable, heating, distension, hydrothorax, ascites, vomiting, dysphagia, the symptoms such as anorexia, significantly alleviated, patient's appetite is increased, spirit takes a turn for the better.
This formula can be also that thin foam is concentrated altogether, makes water-honeyed pill as large in Semen Firmianae, every 10 balls that take, and one day twice, be used for not diffusion of cancerous cell, do not swallow and enclose difficult early stage patient with esophageal carcinoma.
Using method: every day three times, each 10 ml, 7-15 days take effect, and 5-7 the course for the treatment of, some patients were can be cured.
Take this medicine contraindication: the food excitatory that 1, avoids pungent food, 2, coarse, fried, the barbecue of fasting, food really up to the mark, that excessively scald, 3, fasting cigarette, the smoked food that goes mouldy.
Beneficial effect of the present invention:
The Chinese medicinal aqua of the treatment esophageal carcinoma of the present invention, it has blood circulation promoting and blood stasis dispelling, the removing food stagnancy eliminating stagnation, softening the hard mass dispersing tumor, the effect that righting is got rid of evils, there is no negative interaction, the water preparation instant effect, taking convenience all uses than being easier to early, middle and late phase patient with esophageal carcinoma, the patient clinical of opponent's postoperative chemicotherapy is made good use of, and can improve enhancing autoimmunity.
The specific embodiment
Embodiment 1:The medicine of the treatment esophageal carcinoma, the weight portion of its constitutive material is: Hirudo 20 grams, Lignum Dalbergiae Odoriferae 15 grams, Semen Impatientis 25 grams, the Radix Astragali 35 grams, Semen Coicis 50 grams, Poria 30 grams, Radix Paeoniae Rubra 15 grams, the Radix Paeoniae Alba 15 grams, Herba Salviae Chinensis 30 grams, Rhizoma Paridis 15 grams, the Radix Angelicae Dahuricae 15 grams, Fructus Aurantii 30 grams, Thallus Laminariae (Thallus Eckloniae) 50 grams, Sargassum 50 grams, Rhizoma Curcumae 35 grams, Semen Strychni(processed) 10 grams, Scorpio 30 grams, stir-baked SQUAMA MANITIS 30 grams, Realgar 30 grams, Nidus Vespae 30 grams, Bombyx Batryticatus 30 grams, Radix Ginseng 30 grams, Semen Arecae 40 grams and the Radix Linderae 30 grams.
The preparation method of the medicine of the treatment esophageal carcinoma comprises the following steps:
Weight portion by constitutive material takes each raw material, then adds to decoct medicinal herbs vessel, injects 2 kilograms, clear water, soak after 90 minutes, slow fire is endured it, decocts medicinal herbs routinely three times, convert one and endure altogether, little fire is fried in shallow oil to get medicinal liquid approximately after 300ml slowly, injects the 100ml refined honey, slow fire is endured, twist while enduring and mix, get approximately 300ml of medicinal liquid, cold fixed, enter bottle closure, storage.
Curative effect is seen and to be looked into: accept clinic case 40 examples for medical treatment, 30-50 year, in 16 routine 50-70 years, 24 examples are produce effects 6 examples in 30-50 year 16 routine patients wherein, effective 7 examples, invalid 3 examples, effective percentage 81%; In 50-70 year 24 routine patients, produce effects 19 examples, effective 11 examples, invalid 3 examples, effective percentage 89%, total effective rate 84%.
Model case:
Case 1: raise Herba Cymbidii Goeringii, female, 40 years old, Han nationality, Yang Zhuan village, Ying Xian town, conscious throat has foreign body not well more than 3 years, press treatment of chronic pharyngitis, the time sometimes feel twinge after heavy when light, with doing gastroscopy, find that UE has lump apart from throat 2 centimeters, be diagnosed as cancer, not yet diffusion, took anticancer agent on May tenth, 07, after the week, the card shape alleviates, and continues to take medicine ten weeks, be found cancerous cell through confiscating, appetite is normal, and health is good.
Case 2: Li Baodong: man 48 years old, family is toward Funan County Li Xu village, and be diagnosed as the esophageal carcinoma through the Fuyang City the People's Hospital in March, 06, and the position lower esophageal is in the cardia connecting place, operation immediately, chemotherapy, but have soon 2.5 centimeters large lumps to occur under right neck, distending pain is arranged, distending pain under right rib, lack of appetite, poor appetite, health is become thin.The distending pain disappearance after 2 weeks of anticancer liquid medicine is taken in diagnosis and treatment in November, 02, and appetite increases, and continues to take 21 weeks, cures.Normal through looking into all, health is than 1.5 jin of original weightening finishes.
Case 3: Wang Zhifu: man, 63 years old, Wang Zhuan village, senior officer town, Linquan County, the laryngopharynx swelling and pain dysphagia can only be eaten a little soft meals and spoon meat, on JIUYUE 8th, 2009, the People's Hospital looks into through the Linquan County, is diagnosed as esophageal carcinoma, with going to Hefei City phoenix tumour hospital to make Surgery, do for the first time greatly gently, but feel again not well after doing for the second time.Examine in February, 2010, takes the Chinese medicine medicine for preventing water preparation, 10 everyday after, sx↓, the limit clothes do to be got involved with anticancer agent after 5 months in the limit afterwards, are provided with dysphagia to occur, appetite is normal, gun-ho checks base this recovery from illness through Hefei phoenix tumour hospital.
case 4: Zhang Qiang, 70 years old Linquan County people from village in the Western Zhou Dynasty of man, the food acataposis, anti-stream, mucus, out of breath, cough and choke, the haematemesis silk, through Fuyang City the People's Hospital diagnosis of esophageal cancer late period, household's strong request treatment, with operation, rear chemotherapy, patient's body constitution is relatively poor, add year zero larger, aobvious is very painful, the preparation method of medicine of the present invention: seek medical advice, with taking with anticancer agent, after 10 days, doing well,improving, feed is not choked, anti-stream seldom, spirit is few good, ash is multiple to some extent for 20 days muscle power, after three months, feed better, after continuing again to take 5 months, now not recurrence of past 4 year.
Claims (2)
1. a medicine for the treatment of the esophageal carcinoma, is characterized in that the weight portion of its constitutive material is: Hirudo 20 grams, Lignum Dalbergiae Odoriferae 15 grams, Semen Impatientis 25 grams, the Radix Astragali 35 grams, Semen Coicis 50 grams, Poria 30 grams, Radix Paeoniae Rubra 15 grams, the Radix Paeoniae Alba 15 grams, Herba Salviae Chinensis 30 grams, Rhizoma Paridis 15 grams, the Radix Angelicae Dahuricae 15 grams, Fructus Aurantii 30 grams, Thallus Laminariae (Thallus Eckloniae) 50 grams, Sargassum 50 grams, Rhizoma Curcumae 35 grams, Semen Strychni(processed) 10 grams, Scorpio 30 grams, stir-baked SQUAMA MANITIS 30 grams, Realgar 30 grams, Nidus Vespae 30 grams, Bombyx Batryticatus 30 grams, Radix Ginseng 30 grams, Semen Arecae 40 grams and the Radix Linderae 30 grams.
2. the preparation method of the medicine of a treatment esophageal carcinoma as claimed in claim 1 is characterized in that comprising the following steps:
Weight portion by constitutive material takes each raw material, then adds to decoct medicinal herbs vessel, injects 2 kilograms, clear water, soak after 90 minutes, slow fire is endured it, decocts medicinal herbs routinely three times, convert one and endure altogether, little fire fry in shallow oil slowly after medicinal liquid 300ml, inject the 100ml refined honey, slow fire is endured, stir while enduring, get medicinal liquid 300ml, cooling, enter bottle closure, storage.
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| CN1970073A (en) * | 2006-11-28 | 2007-05-30 | 孔祥权 | Chinese medicinal composition for treating pain and preparation process thereof |
| CN101417101A (en) * | 2007-10-24 | 2009-04-29 | 张繁荣 | Barbat skullcap gastric-cancer resistance granules and preparation method thereof |
| CN101745065A (en) * | 2008-12-12 | 2010-06-23 | 董振家 | Pharmaceutical composition with effects of resisting cancer and alleviating pain |
| CN101757566A (en) * | 2010-04-07 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating colon cancer and preparation method thereof |
| CN102274361A (en) * | 2011-07-29 | 2011-12-14 | 李丰曹 | Anticancer medicinal composition and preparation method of decoction thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1970073A (en) * | 2006-11-28 | 2007-05-30 | 孔祥权 | Chinese medicinal composition for treating pain and preparation process thereof |
| CN101417101A (en) * | 2007-10-24 | 2009-04-29 | 张繁荣 | Barbat skullcap gastric-cancer resistance granules and preparation method thereof |
| CN101745065A (en) * | 2008-12-12 | 2010-06-23 | 董振家 | Pharmaceutical composition with effects of resisting cancer and alleviating pain |
| CN101757566A (en) * | 2010-04-07 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating colon cancer and preparation method thereof |
| CN102274361A (en) * | 2011-07-29 | 2011-12-14 | 李丰曹 | Anticancer medicinal composition and preparation method of decoction thereof |
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