CN103520657B - Traditional Chinese medicine composition for treating obese fatty liver - Google Patents
Traditional Chinese medicine composition for treating obese fatty liver Download PDFInfo
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- CN103520657B CN103520657B CN201310510004.XA CN201310510004A CN103520657B CN 103520657 B CN103520657 B CN 103520657B CN 201310510004 A CN201310510004 A CN 201310510004A CN 103520657 B CN103520657 B CN 103520657B
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Abstract
The invention relates to a traditional Chinese medicine composition for treating obese fatty liver. The traditional Chinese medicine composition for treating the obese fatty liver is prepared from the following medicinal raw materials by weight: 20g of radix bupleuri, 20g of fleece-flower root, 20g of medlar, 20g of cassia seed, 15g of hawthorn, 10g of motherwort, 10g of madder, 10g of cortex moutan, 10g of sangusis draconis, 10g of alisma, 10g of radix gentianae, 10g of gardenia jasminoides, 10g of radix curcumae, 10g of radix astragali, 10g of poria cocos, 10g of sealwort, 10g of aspongopus, 10g of angelica, 15g of earthworm, 10g of yam, 10g of christina loosestrife herb, 8g of fructus aurantii immaturus, 8g of schisandra chinensis, 6g of oldenlandia diffusa and 5g of licorice. The medicinal raw materials jointly take effect so as to achieve the effects of protecting the liver, removing heat from the liver, benefiting the gallbladder, lowering and removing lipid, losing weight so as to inhibit the regeneration of fat, promoting the blood circulation of a human body, invigorating spleen-stomach, replenishing qi and nursing five organs, and thus the effect of treating both symptoms and root causes is achieved.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of obese fatty liver, belong to technical field of Chinese medicines.
Background technology
Fatty liver, refers to the pathological changes due to overheap fatty in the hepatocyte that a variety of causes causes.The health of the positive serious threat compatriots of fatty liver disease, becomes the second largest hepatopathy being only second to viral hepatitis, has been acknowledged as the common cause of disguised liver cirrhosis.Can be divided into again according to the cause of disease: alcoholic fatty liver, obese fatty liver, diabetic fatty liver etc.
Easily there is fatty liver in the people of obesity, particularly abdominal obesity.This is because the adipose cell around abdominal part is more responsive to stimulation, so that be delivered to the fatty acid increase of liver by abdominal fat cells.The outlet of intrahepatic fat acid is except partial synthesis phospholipid and cholesterol, main synthesis triacylglycerol, the triacylglycerol of new synthesis is combined at the apolipoprotein in hepatocyte and is released into blood, when synthesize in liver triacylglycerol exceeded liver triacylglycerol transported out the ability of liver time, triacylglycerol just can be caused to pile up in liver and to form fatty liver.Because the obese people of China is more, therefore, the sickness rate of obese fatty liver also rises year by year.
The treatment of current obese fatty liver doctor trained in Western medicine, on the basis of losing weight, emphasize, on the basis of Diet Therapy and exercise therapy, to add and use medicine auxiliary treatment, but therapeutic effect has not good.
Summary of the invention
In order to overcome the shortcoming that above-mentioned prior art exists, the invention provides a kind of Chinese medicine composition for the treatment of obese fatty liver, it effectively can treat obese fatty liver.
Technical scheme of the present invention is: a kind of Chinese medicine composition for the treatment of obese fatty liver, it is characterized in that, be made up of the crude drug of following weight: Radix Bupleuri 20 g, Radix Polygoni Multiflori 20 g, Fructus Lycii 20 g, Semen Cassiae 20 g, Fructus Crataegi 15 g, Herba Leonuri 10 g, Radix Rubiae 10 g, Cortex Moutan 10 g, Sanguis Draxonis 10 g, Rhizoma Alismatis 10 g, Radix Gentianae 10 g, Fructus Gardeniae 10 g, Radix Curcumae 10 g, the Radix Astragali 10 g, Poria 10 g, Rhizoma Polygonati 10 g, Aspongopus 10 g, Radix Angelicae Sinensis 10 g, Pheretima 15 g, Rhizoma Dioscoreae 10g, Herba Lysimachiae 10g, Fructus Aurantii Immaturus 8g, Fructus Schisandrae Chinensis 8g, Herba Hedyotidis Diffusae 6g and Radix Glycyrrhizae 5 g.
Preparation and instructions of taking: soak by water, take at twice sooner or later.Within 7 days, be 1 course for the treatment of, general 3-6 can cure a course for the treatment of.
Radix Bupleuri: bitter, is slightly cold.Return liver, gallbladder, lung meridian.Evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.
Radix Polygoni Multiflori: bitter, sweet, puckery, warm.Return liver, the heart, kidney channel.Removing toxic substances, disappears de-, loosening bowel to relieve constipation.For scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; Hyperlipidemia.
Fructus Lycii: sweet in the mouth, property is put down.Chinese medicine think its can tonifying liver the moon, nourishing the liver blood, replenishing vital essence to improve eyesight.Modern pharmacological research proves: Fructus Lycii energy blood sugar lowering, suppresses fat to deposit in hepatocyte, promotes that hepatocyte is newborn, and has antihypertensive effect.
Semen Cassiae: have another name called Semen Cassiae, its cold nature, sweet-bitter flavor.Fry use, there is effect of liver heat removing and eyesight improving, replenishing YIN and removing heat, loosening bowel to relieve constipation.Modern pharmacological research proves, Semen Cassiae water logging agent and ethanol preserved material have the effect of blood pressure lowering, blood fat reducing and relieving constipation.
Fructus Crataegi: sour, sweet, tepor.Return spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well.
Herba Leonuri: bitter, pungent, is slightly cold.Return liver, pericardium, urinary bladder channel.Promoting blood flow to regulate menstruation, inducing diuresis to remove edema, heat-clearing and toxic substances removing.
Radix Rubiae: bitter, cold.Return Liver Channel.Removing heat from blood, blood stasis dispelling, hemostasis, stimulates the menstrual flow.For spitting blood, epistaxis, metrorrhagia, traumatic hemorrhage, stasis blocking amenorrhea, arthralgia, tumbling and swelling.
Cortex Moutan: bitter in the mouth, pungent, is slightly cold.GUIXIN, liver, kidney channel.Clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Beriberoid pyretic arthralgia.
Sanguis Draxonis: sweet, salty is flat.GUIXIN, Liver Channel.To invigorate blood circulation analgesic therapy, removing stasis to stop bleeding, promoting tissue regeneration and ulcer healing.For traumatic injury, trusted subordinate's stasis of blood pain.Traumatic hemorrhage, skin infection is not held back.
Rhizoma Alismatis: sweet, cold.Return kidney, urinary bladder channel.Function with cure mainly: diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.
Radix Gentianae: bitter, cold.Return lung, Liver Channel.Function with cure mainly: removing heat-phlegm, relieving cough and asthma, detoxification and promoting urination, cooling blood for hemostasis.For cough due to lung-heat, abundant expectoration is panted, and pharyngalgia, aphtha, jaundice due to damp-heat, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage.
Fructus Gardeniae: bitter, cold.GUIXIN, lung, tri-jiao channel.Function with cure mainly: pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Externally used detumescence pain relieving.Vexed for calentura, jaundice due to damp-heat, the puckery pain of stranguria, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles, external treatment bruise pain.
Radix Curcumae: pungent, bitter, cold.Return liver, the heart, lung meridian.Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Function with cure mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Poria: sweet, light is flat.GUIXIN, lung, spleen, kidney channel.Function with cure mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Rhizoma Polygonati: sweet is flat.Return spleen, lung, kidney channel.Function with cure mainly: boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
Aspongopus: salty, temperature.Return liver,spleen,kidney warp.Regulating QI to relieve pain, warming middle-JIAO is supporing yang.For cold syndrome of the stomach distending pain, stomachache due to hyperactive liver-QI attacking the stomach, impotence due to deficiency of the kidney, soreness of waist and knee joint.
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.
Pheretima: salty, cold.Return liver, spleen, urinary bladder channel.Function with cure mainly: heat clearing away is calmed the frightened, and dredging collateral is relievingd asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.
Rhizoma Dioscoreae: sweet, flat.Return spleen, lung, kidney channel.Function with cure mainly: spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Herba Lysimachiae: dry, light, flat, returns liver, gallbladder, kidney, urinary bladder channel.Function with cure mainly: dehumidify jaundice eliminating, inducing diuresis for treating stranguria syndrome, removing toxic substances and promoting subsidence of swelling, Herba Lysimachiae, and picric acid is cool, enters liver and gall kidney, bladder footpath, clearing away heat and promoting diuresis, Tonglin Paishi.
Fructus Aurantii Immaturus: bitter, pungent, sour, is slightly cold.Return spleen, stomach warp.Function with cure mainly: dispelling the stagnated QI removing food stagnancy, loose painful abdominal mass of reducing phlegm.Stop in stagnant, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock of expectorant, the thoracic obstruction, blocked-up chest, visceroptosis.
Fructus Schisandrae Chinensis: sour, sweet, temperature.Return lung, the heart, kidney channel.Function with cure mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, palpitation and insomnia.
Herba Hedyotidis Diffusae: micro-hardship, micro-sweet, is slightly cold.GUIXIN, liver, spleen channel.Function with cure mainly: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, inducing diuresis to remove edema.For laryngopharynx swelling and pain, dyspnea and cough due to lung-heat, the puckery pain of pyretic stranguria, jaundice due to damp-heat, venom, skin ulcer swells hot carbuncle.
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Above-mentioned Chinese medicine combined effect reaches hepatoprotective, fat is dispelled in liver heat removing function of gallbladder promoting, blood fat reducing, lose weight to suppress fat regeneration, strengthens the blood circulation of human body, effect of invigorating the spleen and replenishing QI and conditioning the five internal organs, thus reaches the effect for the treatment of both the principal and secondary aspects of a disease.
One, clinical observation
1. clinical data: out-patient's totally 200 examples being selected from year June in June, 2010 to 2012.Age is 25-67 year, average 39.8 years old, course of disease 1-15.
2. diagnostic criteria:
(1) eating and drinking too much at one meal, hobby delicious food greasy food, namely has at ordinary times and takes in dietary habit that is higher fatty acid, high heat;
(2) overweight body weight is above standard body weight more than 10%;
(3) clinical manifestation is asymptomatic, or has fatigue and weak, uncomfortable liver area, distension, even dull pain, anorexia, face acne etc.;
(4) lab testing: alanine aminotransferase (glutamate pyruvate transaminase) (ALT) and aspartate aminotransferase (glutamic oxaloacetic transaminase, GOT) (AST) raises, and ALT/AST ratio is greater than 1; Globulin raises, and albumin, globulin are lacked of proper care; Serum phosphatase level raises, most of patients raises (especially triacylglycerol rising) with blood fat, is the feature performance of fatty liver, or companion's hypercholesterolemia;
(5) ultrasound diagnosis liver B-type ultrasonography, visible fat liver image, that is: the strong echo in hepatic region, the contrast of Liver and kidney brightness district declines, sclerosis of blood vessels in liver, and gallbladder wall disappears.
3. Therapeutic Method: take medicine of the present invention, soak by water, takes at twice sooner or later.It within 7 days, is 1 course for the treatment of.
4. efficacy assessment standard: cure: 1. transference cure, blood fat, liver function are normal, and B ultrasonic shows that fatty liver wave mode disappears, and liver bounces back to normally; 2. effective: symptom disappears substantially, blood fat, liver function are bordering on normally, and B ultrasonic shows that fatty liver wave mode disappears substantially, and liver obviously bounces back and is bordering on normally; 3. effective: symptom major part disappears, and blood fat, liver function take a turn for the better, and B ultrasonic shows that fatty liver wave mode reduces, and liver slightly bounces back; 4. invalid: symptom and every inspection have no improvement.
5. therapeutic outcome: cure 183 examples, effective 12 examples, effective 5 examples, invalid 0 example.Total effective rate is 100%.
Two, model case
Case 1: Zhang, man, 45 years old, addicted to greasy.Height 172cm before treatment, there is right epigastric discomfort before treatment, weak companion's both sides of the chest distending pain in body weight 102 kilograms, is diagnosed as obese fatty liver through B ultrasonic display.After taking medicine of the present invention 3 courses for the treatment of (period in a medicine not edible oil is greasy), all diseases all disappear.B ultrasonic shows that liver recovers normal, and lose weight 8kg.Control greasy subsequently, after eating stodge less, after half a year, body weight is down to 82 kilograms as far as possible.
Case 2: Wang, man, 40 years old, height 175cm, addicted to greasy.Within 2012, occur right flank dull pain, upper abdomen distension, borborygmus, loose stool, extremity are aching and tired unable, body weight 105 kg.B ultrasonic shows for fatty liver.After taking 3 courses for the treatment of of medicine of the present invention.B ultrasonic shows that liver recovers normal, loses weight 10 kilograms.
Detailed description of the invention
Embodiment 1
Formula: Radix Bupleuri 20 g, Radix Polygoni Multiflori 20 g, Fructus Lycii 20 g, Semen Cassiae 20 g, Fructus Crataegi 15 g, Herba Leonuri 10 g, Radix Rubiae 10 g, Cortex Moutan 10 g, Sanguis Draxonis 10 g, Rhizoma Alismatis 10 g, Radix Gentianae 10 g, Fructus Gardeniae 10 g, Radix Curcumae 10 g, the Radix Astragali 10 g, Poria 10 g, Rhizoma Polygonati 10 g, Aspongopus 10 g, Radix Angelicae Sinensis 10 g, Pheretima 15 g, Rhizoma Dioscoreae 10g, Herba Lysimachiae 10g, Fructus Aurantii Immaturus 8g, Fructus Schisandrae Chinensis 8g, Herba Hedyotidis Diffusae 6g and Radix Glycyrrhizae 5 g.
Preparation and instructions of taking: soak by water, take at twice sooner or later.It within 7 days, is 1 course for the treatment of.
Claims (1)
1. treat the Chinese medicine composition of obese fatty liver for one kind, it is characterized in that, be made up of the crude drug of following weight: Radix Bupleuri 20 g, Radix Polygoni Multiflori 20 g, Fructus Lycii 20 g, Semen Cassiae 20 g, Fructus Crataegi 15 g, Herba Leonuri 10 g, Radix Rubiae 10 g, Cortex Moutan 10 g, Sanguis Draxonis 10 g, Rhizoma Alismatis 10 g, Radix Gentianae 10 g, Fructus Gardeniae 10 g, Radix Curcumae 10 g, the Radix Astragali 10 g, Poria 10 g, Rhizoma Polygonati 10 g, Aspongopus 10 g, Radix Angelicae Sinensis 10 g, Pheretima 15 g, Rhizoma Dioscoreae 10g, Herba Lysimachiae 10g, Fructus Aurantii Immaturus 8g, Fructus Schisandrae Chinensis 8g, Herba Hedyotidis Diffusae 6g and Radix Glycyrrhizae 5 g.
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| CN105287798A (en) * | 2015-10-24 | 2016-02-03 | 张国显 | Lipid-lowering and slimming recovery pill |
| CN106074918A (en) * | 2016-07-04 | 2016-11-09 | 深圳市中医院 | A kind of soothing the liver fat Chinese medicine composition that disappears treating non-alcohol fatty liver |
| CN108970028B (en) * | 2018-08-24 | 2020-04-21 | 南昌师范学院 | Training method capable of improving body endurance |
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| CN1124153C (en) * | 2001-08-31 | 2003-10-15 | 石家庄以岭药业股份有限公司 | Medicinal composition for restoring cardiac collaterals and its application |
| CN101181600B (en) * | 2007-11-20 | 2010-07-21 | 王振才 | Traditional Chinese medicine composition for curing cardiovascular and cerebrovascular diseases |
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Granted publication date: 20150304 Termination date: 20171025 |