CN101181600B - Traditional Chinese medicine composition for curing cardiovascular and cerebrovascular diseases - Google Patents
Traditional Chinese medicine composition for curing cardiovascular and cerebrovascular diseases Download PDFInfo
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Abstract
The invention relates to a Chinese medical compound for curing cardiovascular disease, and is prepared by the following raw medicines: green tangerine peel, bupleurum, nutgrass galingale rhizome, turmeric root-tuber, pittosporm root, gentiana scabra bge, black nightshade herb, gambir plant, tuber fleeceflower root broil, radix astragali, cassia twig, ageratum, plantain seed, south dodder seed, red paeony root, szechuan lovage rhizome, kudzuvine root, malaytea scurfpea fruit, danshen root, hawthorn, safflower, pericarpium trichosanthis, blackberrykiky rhizome, tree peony bark, india madder root, dangshen, sojutsu var broil, indian buead, chicken's gizzard-membrane, combined spicebush root, cinnamon, baical skullcap root, ephedra herb, chinese magnoliavine fruit, fragrant solomonseal rhizome, radix stemonae broil, pinellia tuber broil, white mustard seed, nodakenin, sandalwood, rosewood heart wood, longstamen onion bulb, angelica, clematis root, kadsura pepper stem, ovientvine, herb pyrolae, desertliving cistanche, hairy antler, medicinal indianmulberry root, barbary wolfberry fruit, glossy privet fruit, dogwood, rhizoma anemarrhenae, amur corktree bark, spina date seed, platycladi seed, pubescent holly root, thinleaf milkwort root-bark broil, grassleaf sweelflag rhizome, silktree albizzia bark, twotooth achyranthes root, paris polyphylla, chinese date, oriental waterplantain rhizome, songaria cynomorium herb, papermulberry fruit, leech, cortex lycii radicis, earthworm, lucid ganoderma, glabrous greenbrier rhizome, magnetic stone dust, and longhairy antenoron herb with small leaves. The invention has good curing effects on the applicable diseases.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine, particularly a kind of Chinese medicine composition that is used for the treatment of cardiovascular and cerebrovascular disease is the clinical treatment medicine of cardiovascular and cerebrovascular disease first-selections such as coronary heart disease, angina pectoris, myocardial infarction, cerebral thrombosis and heart failure.
Background technology
Well-known cardiovascular and cerebrovascular disease, the pertinacious disease that become obstinate, show effect repeatedly and caused death, disability rate is high makes the patient bear huge fear and painful.Although the medicine of treatment cardiovascular and cerebrovascular disease was a feast for the eyes on the market in the past, the medicine that has is very fast as the superfluous compound of the cholic acid of treatment hyperlipidemia, fibrate drug blood fat reducing, but side effect clearly, take for a long time and can cause hepatic lesions, and, but weak curative effect less with nicotinic acid, pantethin class medicine blood fat reducing side effect; Nitrate esters, calcium antagonist, receptor blocking agent and the antiplatelet drug etc. of treatment coronary heart disease, angina pectoris, myocardial infarction all have very big side effect.Can cause that as nitrate esters headache is flushing, tinnitus is dizzy and tachycardia, can cause blood pressure to plunge sometimes, cause collapse and produce drug resistance; Calcium antagonist mainly reduces cardiac load by coronary artery dilator and systemic arterial, is a kind of emergency treatment commonly used, yet blood vessel dilating is easy to cause that heart beating is slow excessively, heart failure and dependency are strong, and the hypotensive uses and can die suddenly; The dependency of receptor blocking agent is very strong, and drug withdrawal meeting suddenly makes the state of an illness more serious; Antiplatelet drug then can cause side effect such as digestive tract hemorrhage.These medicines not only side effect are big, and toxicity is also very strong, can damage the Liver and kidney organ, causes new drug-induced disease and multiple complications, can only can not take for a long time, otherwise consequence be hardly imaginable as the emergent drug use of short-term.Because described pharmic function is single cures the symptoms, not the disease again.When doctors use above-mentioned treatment means when invalid repeatedly, just have an operation, adorn support, heart pass etc.Cure the symptoms, not the disease although this still belongs to, be doctors at and helpless selection.
Summary of the invention
The present invention is directed to above-mentioned problems of the prior art, according to causing the cardiovascular and cerebrovascular disease reason, adopt many compound recipes of multi-flavor medicine scientific composition, to unbalance liver, lung, spleen, kidney, that heart the five internal organs integral body is carried out the many targets of comprehensively regulating is synchronous, make himself each Xingqi duty of restore funcitons, treating both the principal and secondary aspects of a disease, control are obvious in conjunction with curative effect, and cure rate height, medicine stop the Chinese medicine composition of the treatment cardiovascular disease that do not rebound, have no side effect.
The principles of formulating prescriptions of the present invention are to be the equilibrium system of a complexity according to human body, and normal person self has certain immunocompetence, but owing to undesirable elements such as life style, environmental pollution and improper diet disequilibrate diseases induced.Unbalance as blood circulation, thrombosis forms blood dirt deposition and thrombosis, makes sclerosis of blood vessels, narrow and influence the blood supply oxygen supply of organ jointly, finally causes organ lesion.Aggravate blood contamination and vascular lesion conversely more, metabolism disorder of blood lipid in the blood, and then produce a large amount of oxygen-derived free radicals, microcirculation is obstructed, organ lesion aggravation enters vicious cycle, until uncontrollable.Occur various clinical manifestations such as coronary heart disease, angina pectoris, heart infarction, heart failure, atherosclerosis in succession, this is a kind of form of expression of ill result.At morbific all multifactor, adopt many targets synchronization in blood, blood vessel, five internal organs and whole circulation system by dissolving, mediation, cleaning, repair comprehensively regulating function of five internal organs when eliminating clinical manifestation, make it to reach gradually running and coordinate each Xingqi duty, finally make physical rehabilitation.
Chinese medicine composition of the present invention be by following bulk drugs by weight through being prepared from:
Pericarpium Citri Reticulatae Viride 4-6, Radix Bupleuri 3-5, Rhizoma Cyperi 3-5, Radix Curcumae 4-6, Fructus Gardeniae 4-6, Radix Gentianae 4-6, Herba Solani Nigri 4-6, Ramulus Uncariae Cum Uncis 3-5, Radix Paeoniae Alba 8-10, Radix Polygoni Multiflori is processed 6-8, Radix Astragali 4-6, Ramulus Cinnamomi 3-5, Herba Pogostemonis 4-6, Semen Plantaginis 3-5, Semen Cuscutae 3-5, Radix Paeoniae Rubra 6-8, Rhizoma Chuanxiong 3-5, Radix Puerariae 6-8, Fructus Psoraleae 6-8, Radix Salviae Miltiorrhizae 4-6, Fructus Crataegi 8-10, Flos Carthami 4-6, fruit-rind of Chinese trichosanthes 8-10, Rhizoma Belamcandae 8-10, Cortex Moutan 6-8, Radix Rubiae 4-6, Radix Codonopsis 4-6, the Rhizoma Atractylodis Macrocephalae is processed 3-5, Poria 4-6, Endothelium Corneum Gigeriae Galli 3-5, Radix Linderae 3-5, Cortex Cinnamomi 3-5, Radix Scutellariae 6-8, Herba Ephedrae 3-5, Fructus Schisandrae Chinensis 2-4, Rhizoma Polygonati Odorati 4-6, the Radix Stemonae is processed 3-5, the Rhizoma Pinelliae is processed 3-5, Semen Sinapis Albae 3-5, Radix Peucedani 4-6, Lignum Santali Albi 6-8, Lignum Dalbergiae Odoriferae 6-8, Bulbus Allii Macrostemonis 4-6, Rhizoma Et Radix Notopterygii 3-5, Radix Clematidis 3-5, Caulis Piperis Kadsurae 3-5, Caulis Sinomenii 3-5, Herba Pyrolae 4-6, Herba Cistanches 4-6, Cornu Cervi Pantotrichum 2-3, Radix Morindae Officinalis 4-6, Fructus Lycii 3-5, Fructus Ligustri Lucidi 4-6, Fructus Corni 4-6, Rhizoma Anemarrhenae 3-5, Cortex Phellodendri 3-5, Semen Ziziphi Spinosae 4-6, Semen Platycladi 4-6, Radix Ilicis Pubescentis 6-8, Radix Polygalae is processed 3-5, Rhizoma Acori Graminei 4-6, Cortex Albiziae 6-8, Radix Achyranthis Bidentatae 4-6, seven leaves-branch flower 3-5, Fructus Jujubae 4-6, Rhizoma Alismatis 3-5, Herba Cynomorii 3-5, Fructus Broussonetiae 3-5, Hirudo 4-6, Cortex Lycii 3-5, dried Pheretima 6-8, Ganoderma 3-5, Rhizoma Smilacis Glabrae 3-5, Magnetitum powder 10-20, lobule Herba Lysimachiae 4-6.
Prescription of the present invention is based on conditioning liver, spleen, lung, kidney, excite to strengthen the running of the five internal organs Total tune, recovery itself to the blood self-dissolving, change certainly, filter certainly, from cleer and peaceful self-cleaning function, help medicine again with the elimination clinical manifestation.As breaking the liver stasis of blood stagnation of QI with Pericarpium Citri Reticulatae Viride, Radix Bupleuri, Rhizoma Cyperi soothing liver-QI are rubbed liver reason irritability; Radix Curcumae, Fructus Gardeniae, Radix Gentianae clearing away liver-fire function of gallbladder promoting are to increase the cholate secretory volume; Radix Gentianae, Herba Solani Nigri, Radix Scutellariae are separated the liver poison, let out the fire of liver and gall; Ramulus Uncariae Cum Uncis suppressing the hyperactive liver sun, the Radix Paeoniae Alba, Radix Polygoni Multiflori tonifying liver blood nourishing the liver hepatoprotective, dried Pheretima, Flos Carthami blood pressure lowering, more than all medicines attack benefit, let out, put down, rub double the synthetic of materials such as promoting heparin, lysozyme, sternzellen that impose, help again with the Radix Astragali, Ramulus Cinnamomi, Herba Pogostemonis, Flos Carthami, expansion small artery, arteriole blood vessel; With Radix Paeoniae Rubra, Rhizoma Chuanxiong, Radix Puerariae, Fructus Psoraleae, the Radix Astragali, Radix Salviae Miltiorrhizae, Fructus Crataegi, Flos Carthami, Radix Ilicis Pubescentis expansion hat tremulous pulse, cerebral arteries and big-and-middle arteries; Rubbish things such as the fruit-rind of Chinese trichosanthes, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Polygoni Multiflori prevention or minimizing cholesterol deposit on blood vessel wall; Dead blood, old blood, stagnant blood on the Radix Paeoniae Alba, Rhizoma Belamcandae, the Hirudo dissolving blood vessel wall; The Cortex Moutan removing heat from blood bolt that purifies the blood does not stay the stasis of blood, and Fructus Crataegi, Radix Scutellariae, Fructus Jujubae are cleared up the anti-bad blood of bad blood, and Radix Ilicis Pubescentis, Flos Carthami, Radix Salviae Miltiorrhizae increase coronary flow, Flos Carthami, Cortex Moutan, lobule Herba Lysimachiae, Fructus Crataegi cleaning venous blood enduringly; Herba Pogostemonis is amusing; The Rhizoma Atractylodis Macrocephalae, Poria, Radix Codonopsis, Radix Astragali spleen reinforcing, Fructus Crataegi, Endothelium Corneum Gigeriae Galli spleen invigorating, activating the spleen is aid digestion, and Endothelium Corneum Gigeriae Galli, Fructus Crataegi, the Radix Linderae help gastrointestinal peristalsis simultaneously, Cortex Cinnamomi, the warm spleen of the Radix Linderae, stomach, kidney, cold foul smell disappears; Radix Codonopsis, Radix Astragali tonifying liver gas, Rhizoma Polygonati Odorati, the Radix Stemonae are grown the lung nourishing the lung to arrest cough, the solid lung qi of Fructus Schisandrae Chinensis, Herba Ephedrae, Ramulus Cinnamomi lung qi dispersing diarrhea due to disorder of QI water, Radix Scutellariae is let out lung-fire, the Rhizoma Pinelliae, the cold stasis of blood of Semen Sinapis Albae lung heat clearingization, the fruit-rind of Chinese trichosanthes, Radix Peucedani, Rhizoma Belamcandae lung heat clearing heat-transformation expectorant throat; Lignum Santali Albi, Bulbus Allii Macrostemonis, Lignum Dalbergiae Odoriferae are transferred all gas and circulation of qi promoting on the diaphragm, and Rhizoma Et Radix Notopterygii, Radix Clematidis, Caulis Piperis Kadsurae, Herba Pyrolae, Herba Pogostemonis are dispeled the wind removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral to remove the thoracic obstruction, the removing dampness of dispeling the wind; Cornu Cervi Pantotrichum, Herba Cistanches, Fructus Psoraleae, Radix Morindae Officinalis, Radix Polygoni Multiflori kidney-replenishing help kidney qi to add the smart marrow of mending, Fructus Lycii, Fructus Ligustri Lucidi, Fructus Corni, the Rhizoma Anemarrhenae, Semen Cuscutae nourishing kidney yin, promote equilibrium between yin and yang, gas reinforces the kidney, Fructus Psoraleae, Magnetitum powder are received kidney qi, and Cortex Phellodendri, the Rhizoma Anemarrhenae, Cortex Moutan, Cortex Lycii are let out kidney fireflood deficiency-heat; Mending gate of vitality's fire with Cornu Cervi Pantotrichum, Cortex Cinnamomi, Radix Linderae warming and recuperating the kidney-YANG helps the functioning of bladder urinary tract unimpeded; Semen Ziziphi Spinosae, Semen Platycladi, the Radix Paeoniae Alba, Radix Polygoni Multiflori, the Cornu Cervi Pantotrichum reinforcing the heart blood blood that nourishes heart, Cortex Cinnamomi, Radix Codonopsis, Cornu Cervi Pantotrichum is inspired heart-yang, Herba Pyrolae, the Rhizoma Pinelliae, Rhizoma Et Radix Notopterygii, Rhizoma Acori Graminei, Radix Peucedani is adjusted heart rate, the Radix Achyranthis Bidentatae conducting blood to flow downwards, Radix Polygalae, Rhizoma Acori Graminei, the Cortex Albiziae refreshment sedate of having one's ideas straightened out, Semen Plantaginis, the Semen Cuscutae liver heat removing and eyesight improving, Fructus Jujubae, Cortex Albiziae, Herba Solani Nigri, Cornu Cervi Pantotrichum, Herba Cistanches, Rhizoma Polygonati Odorati, the fruit-rind of Chinese trichosanthes strong body of making light of one's life by commiting suicide, recovery prolonged illness weakness, Rhizoma Alismatis, Semen Plantaginis, accumulate toxin in the clear body of Poria and just discharge from two, Fructus Crataegi, Rhizoma Alismatis, Flos Carthami, Radix Scutellariae, the Radix Astragali, Herba Cistanches, Rhizoma Polygonati Odorati, the Radix Paeoniae Alba, Radix Bupleuri, the fruit-rind of Chinese trichosanthes, Radix Codonopsis, Fructus Jujubae, Cortex Moutan, Rhizoma Belamcandae blood fat reducing and alleviation and improve myocardial infarction, the Magnetitum powder tranquillization with heavy prescription, suppressing the hyperactive liver and subsiding YANG draws the gas of lung gold and goes into kidney.Adopt multidigit medicine, many compound recipes, big prescription, many targets synchronization, could eliminate pathogenesis, treating both the principal and secondary aspects of a disease so that rehabilitation, and scientific and reasonable through clinical its prescription of proof.
The present invention compared with prior art, because prescription is at pathogenic factor, adopt the many targets of the big prescription of multidigit medicine synchronously unbalance internal organs to be carried out the whole synthesis conditioning, make it each Xingqi duty, help simultaneously to eliminate the technical measures such as medicine of clinical symptoms, and by clinical proof have to the indication effective percentage reach 100%, cure rate reaches more than 95%, not rebounding after more is the result for the treatment of both the principal and secondary aspects of a disease, takes for a long time to have no side effect and dependency; Make the patient break away from the pain and fear sense that the serious illness torments, health obtains the life that the normal person is crossed in rehabilitation.
The specific embodiment
Content of the present invention is described in detail by embodiment, but not limit by embodiment.
Embodiment 1
Proportioning by prescription is got 4 parts on Pericarpium Citri Reticulatae Viride, 5 parts of Radix Bupleuri, 3 parts of Rhizoma Cyperis, 6 parts of Radix Curcumaes, 6 parts of Fructus Gardeniae, 4 parts of Radix Gentianaes, 5 parts of Herba Solani Nigris, 4 parts of Ramulus Uncariae Cum Uncis, 10 parts of the Radix Paeoniae Albas, Radix Polygoni Multiflori is processed 6 parts, 5 parts of the Radixs Astragali, 5 parts of Ramulus Cinnamomi, 5 parts of Herba Pogostemoniss, 5 parts of Semen Plantaginiss, 5 parts of Semen Cuscutae, 8 parts of Radix Paeoniae Rubra, 3 parts of Rhizoma Chuanxiongs, 6 parts of Radix Puerariaes, 8 parts of Fructus Psoraleaes, 5 parts of Radix Salviae Miltiorrhizaes, 9 parts of Fructus Crataegis, 6 parts on Flos Carthami, 8 parts of the fruit-rinds of Chinese trichosanthes, 10 parts of Rhizoma Belamcandae, 6 parts of Cortex Moutans, 4 parts in Radix Rubiae, 5 parts of Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae is processed 5 parts, 4 parts in Poria, 5 parts of Endothelium Corneum Gigeriae Galli, 3 parts of the Radixs Linderae, 3 parts of Cortex Cinnamomis, 6 parts of Radix Scutellariaes, 5 parts in Herba Ephedrae, 2 parts of Fructus Schisandrae Chinensis, 4 parts of Rhizoma Polygonati Odorati, the Radix Stemonae is processed 5 parts, the Rhizoma Pinelliae is processed 3 parts, 5 parts of Semen Sinapis Albaes, 4 parts of Radix Peucedanis, 6 parts in Lignum Santali Albi, 8 parts of Lignum Dalbergiae Odoriferaes, 4 parts of Bulbus Allii Macrostemonis, 3 parts of Rhizoma Et Radix Notopterygiis, 5 parts of Radix Clematidis, 3 parts of Caulis Piperis Kadsuraes, 5 parts of Caulis Sinomeniis, 4 parts of Herba Pyrolaes, 5 parts of Herba Cistanches, 3 parts in Cornu Cervi Pantotrichum, 4 parts of Radix Morindae Officinaliss, 3 parts of Fructus Lycii, 4 parts of Fructus Ligustri Lucidi, 6 parts of Fructus Corni, 3 parts of the Rhizoma Anemarrhenaes, 5 parts of Cortex Phellodendris, 6 parts of Semen Ziziphi Spinosaes, 4 parts of Semen Platycladi, 8 parts of Radix Ilicis Pubescentiss, Radix Polygalae is processed 3 parts, 6 parts of Rhizoma Acori Graminei, 6 parts of Cortex Albiziaes, 4 parts of Radix Achyranthis Bidentataes, 3 parts of Rhizoma Paridis, 6 parts in Fructus Jujubae, 5 parts of Rhizoma Alismatis, 3 parts of Herba Cynomoriis, 5 parts of Fructus Broussonetiaes, 4 parts of Hirudos, 5 parts of Cortex Lycii, 8 parts of dried Pheretima, 3 parts of Ganodermas, 5 parts of Rhizoma Smilacis Glabraes, 15 parts of Magnetitum powder, 4 parts of lobule Herba Lysimachiaes, drying, be ground into powder, be ground into fine powder, encapsulated 0.7 gram/grain stirs.
Embodiment 2
Get 6 parts on Pericarpium Citri Reticulatae Viride, 3 parts of Radix Bupleuri, 5 parts of Rhizoma Cyperis, 4 parts of Radix Curcumaes, 5 parts of Fructus Gardeniae, 5 parts of Radix Gentianaes, 6 parts of Herba Solani Nigris, 5 parts of Ramulus Uncariae Cum Uncis, 8 parts of the Radix Paeoniae Albas, Radix Polygoni Multiflori is processed 8 parts, 4 parts of the Radixs Astragali, 3 parts of Ramulus Cinnamomi, 4 parts of Herba Pogostemoniss, 3 parts of Semen Plantaginiss, 4 parts of Semen Cuscutae, 6 parts of Radix Paeoniae Rubra, 5 parts of Rhizoma Chuanxiongs, 8 parts of Radix Puerariaes, 6 parts of Fructus Psoraleaes, 5 parts of Radix Salviae Miltiorrhizaes, 9 parts of Fructus Crataegis, 5 parts on Flos Carthami, 9 parts of the fruit-rinds of Chinese trichosanthes, 8 parts of Rhizoma Belamcandae, 8 parts of Cortex Moutans, 5 parts in Radix Rubiae, 4 parts of Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae is processed 3 parts, 6 parts in Poria, 3 parts of Endothelium Corneum Gigeriae Galli, 4 parts of the Radixs Linderae, 5 parts of Cortex Cinnamomis, 7 parts of Radix Scutellariaes, 3 parts in Herba Ephedrae, 4 parts of Fructus Schisandrae Chinensis, 6 parts of Rhizoma Polygonati Odorati, the Radix Stemonae is processed 3 parts, the Rhizoma Pinelliae is processed 5 parts, 3 parts of Semen Sinapis Albaes, 6 parts of Radix Peucedanis, 8 parts in Lignum Santali Albi, 6 parts of Lignum Dalbergiae Odoriferaes, 6 parts of Bulbus Allii Macrostemonis, 5 parts of Rhizoma Et Radix Notopterygiis, 3 parts of Radix Clematidis, 5 parts of Caulis Piperis Kadsuraes, 3 parts of Caulis Sinomeniis, 6 parts of Herba Pyrolaes, 4 parts of Herba Cistanches, 2 parts in Cornu Cervi Pantotrichum, 6 parts of Radix Morindae Officinaliss, 5 parts of Fructus Lycii, 6 parts of Fructus Ligustri Lucidi, 4 parts of Fructus Corni, 5 parts of the Rhizoma Anemarrhenaes, 3 parts of Cortex Phellodendris, 4 parts of Semen Ziziphi Spinosaes, 6 parts of Semen Platycladi, 6 parts of Radix Ilicis Pubescentiss, Radix Polygalae is processed 4 parts, 4 parts of Rhizoma Acori Graminei, 8 parts of Cortex Albiziaes, 6 parts of Radix Achyranthis Bidentataes, 4 parts of Rhizoma Paridis, 4 parts in Fructus Jujubae, 3 parts of Rhizoma Alismatis, 5 parts of Herba Cynomoriis, 3 parts of Fructus Broussonetiaes, 6 parts of Hirudos, 3 parts of Cortex Lycii, 6 parts of dried Pheretima, 5 parts of Ganodermas, 3 parts of Rhizoma Smilacis Glabraes, 20 parts of Magnetitum powder, 5 parts of lobule Herba Lysimachiaes, drying, be ground into powder, add excipient and make coated tablet 1 gram/sheet.Contain effective dose 0.7 gram/sheet, each 5 slice, days clothes secondary.
Embodiment 3
Get raw material medicated powder 3500g that embodiment 2 makes and add Mel 2500g and make honeyed pill 1000 balls, 6 gram/balls, wherein contain effective dose 3.5g, each ball, day clothes secondary.
Embodiment 4
Get 5 parts on Pericarpium Citri Reticulatae Viride, 4 parts of Radix Bupleuri, 4 parts of Rhizoma Cyperis, 5 parts of Radix Curcumaes, 4 parts of Fructus Gardeniae, 6 parts of Radix Gentianaes, 4 parts of Herba Solani Nigris, 3 parts of Ramulus Uncariae Cum Uncis, 9 parts of the Radix Paeoniae Albas, Radix Polygoni Multiflori is processed 7 parts, 6 parts of the Radixs Astragali, 4 parts of Ramulus Cinnamomi, 6 parts of Herba Pogostemoniss, 4 parts of Semen Plantaginiss, 3 parts of Semen Cuscutae, 7 parts of Radix Paeoniae Rubra, 4 parts of Rhizoma Chuanxiongs, 7 parts of Radix Puerariaes, 7 parts of Fructus Psoraleaes, 5 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Crataegis, 4 parts on Flos Carthami, 10 parts of the fruit-rinds of Chinese trichosanthes, 9 parts of Rhizoma Belamcandae, 7 parts of Cortex Moutans, 6 parts in Radix Rubiae, 6 parts of Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae is processed 4 parts, 5 parts in Poria, 4 parts of Endothelium Corneum Gigeriae Galli, 4 parts of the Radixs Linderae, 4 parts of Cortex Cinnamomis, 8 parts of Radix Scutellariaes, 4 parts in Herba Ephedrae, 3 parts of Fructus Schisandrae Chinensis, 5 parts of Rhizoma Polygonati Odorati, the Radix Stemonae is processed 4 parts, the Rhizoma Pinelliae is processed 4 parts, 4 parts of Semen Sinapis Albaes, 5 parts of Radix Peucedanis, 7 parts in Lignum Santali Albi, 7 parts of Lignum Dalbergiae Odoriferaes, 5 parts of Bulbus Allii Macrostemonis, 4 parts of Rhizoma Et Radix Notopterygiis, 4 parts of Radix Clematidis, 4 parts of Caulis Piperis Kadsuraes, 4 parts of Caulis Sinomeniis, 5 parts of Herba Pyrolaes, 5 parts of Herba Cistanches, 3 parts in Cornu Cervi Pantotrichum, 5 parts of Radix Morindae Officinaliss, 4 parts of Fructus Lycii, 5 parts of Fructus Ligustri Lucidi, 5 parts of Fructus Corni, 4 parts of the Rhizoma Anemarrhenaes, 4 parts of Cortex Phellodendris, 5 parts of Semen Ziziphi Spinosaes, 5 parts of Semen Platycladi, 7 parts of Radix Ilicis Pubescentiss, Radix Polygalae is processed 4 parts, 5 parts of Rhizoma Acori Graminei, 7 parts of Cortex Albiziaes, 5 parts of Radix Achyranthis Bidentataes, 5 parts of Rhizoma Paridis, 5 parts in Fructus Jujubae, 4 parts of Rhizoma Alismatis, 4 parts of Herba Cynomoriis, 4 parts of Fructus Broussonetiaes, 5 parts of Hirudos, 4 parts of Cortex Lycii, 7 parts of dried Pheretima, 4 parts of Ganodermas, 4 parts of Rhizoma Smilacis Glabraes, 10 parts of Magnetitum powder, 6 parts of lobule Herba Lysimachiaes, drying, be ground into graininess, it is standby to stir, get in the pure grain 50 degree Chinese liquor that 5-6 part crude drug adds 100 parts of weight and soaked 20 days, room temperature, morning and afternoon every day, each stirred once, cross leaching filtrate, fill 500ml/ bottle, every day 2 times, each 25ml, ill curing the disease, anosis health care.
Dosage form of the present invention is unrestricted, and interpolation acceptable excipient of pharmaceutics or carrier can be made into powder, capsule, tablet, ball and medicated wine and all can.Ethanol allergy, severe hypertension, heart failure and arrhythmia person are forbidden medicated wine, take taboo edible mung bean food during the medicine of the present invention.
Clinical trial curative effect of medication visual report of the present invention
For the curative effect of further examining medicine of the present invention is carried out clinical trial to 150 examples through making a definite diagnosis the patient who suffers from coronary heart disease, angina pectoris and myocardial infarction, contrast under patient's the identical or proximate situation of the state of an illness, medical history, disease time and doctor's technical merit, concrete condition is as follows.
One, clinical data:
Clinical verification selects case all to meet every requirement of defined in the checking design, to be in hospital and clinic case selects 150 examples, and test group 100 examples wherein, matched group 50 examples.Each organizes sex, and the age sees Table 1.
Each test group sex of table 1, age
| Group | Total routine number | Age | Sex | |||
| ?40-60 | ?61-70 | ?71-85 | The man | The woman | ||
| Test group | 100 | ?15 | ?72 | ?13 | ?70 | ?30 |
| Matched group | 50 | ?5 | ?35 | ?10 | ?35 | ?15 |
| Add up to | 150 | ?20 | ?107 | ?23 | ?105 | ?45 |
Table 2 clinical manifestation
Two, dosage and method
Test group: the each 6g/ ball of medicine of the present invention, every day 2 times, eliminating cold for resuscitation mouth of a river clothes are 1 course of treatment all around on an empty stomach.
Matched group: the logical sheet of hat, every day 2 times, each 5, eliminating cold for resuscitation mouth of a river clothes are 1 course of treatment all around on an empty stomach.In the process of test, cut out the medicine of other treatment coronary heart disease, angina pectoris and myocardial infarction class, and the diet mung bean food
Three, criterion of therapeutical effect and judgement:
1, criterion of therapeutical effect:
Effectively: coronary heart disease, angina pectoris and heart infarction symptom have clear improvement
Produce effects: coronary heart disease, angina pectoris and heart infarction symptom are most of to disappear
Invalid: coronary heart disease, angina pectoris and heart infarction doing well,improving are not obvious
Recovery from illness: coronary heart disease, angina pectoris and the complete obiteration of heart infarction symptom.
2, therapeutic outcome is judged:
Efficient statistics and significance compare: test group and the comparison sheet x of matched group than curative effect difference
2The statistical processing methods of test:
The efficient statistics of table 3
| Group | Total routine number | Cure rate % | Effective percentage % | Invalid | Total effective rate % | |||
| Example | ?％ | Effectively | Produce effects | Example | ％ | |||
| Test group | 100 | ?98 | ?98 | ?100 | ?2 | ?0 | ?0 | 100 |
| Contrast | 50 | ?0 | ?0 | ?20 | ?15 | ?15 | ?30％ | 70 |
| Group |
Through x
2Check, test group total effective rate 100%, matched group total effective rate are 70% test group and matched group curative effect significant difference.
Table 4 effectively compares the course of treatment
| Group | Total routine number | Effective time (my god) | The effective time sky (my god) | Cure time (my god) | |||||
| ?30 | ?60 | ?60 | ?90 | ?120 | ?90 | ?120 | ?150 | ||
| Test group | 100 | ?85 | ?15 | ?45 | ?35 | ?20 | ?35 | ?58 | ?5 |
| Matched group | 50 | ?30 | ?5 | ?0 | ?15 | ?0 | ?0 | ?0 | ?0 |
The effectively comparative analysis course of treatment: the test group treatment shortest time is 30-60 days, and what reach effective standard is 100%.
The treatment of control group time is 30-60 days, and what reach effective standard is 70%, test group and matched group significant difference.
From this group clinical statistics, the total effective rate 100% of medicine of the present invention, cure rate 98%; Remove two routine heart infarction patients owing to the time is short, the outer rehabilitation of all fully recovering of also failing to fully recover five courses of treatment.Though and the matched group responding time is very fast, just mitigate the disease can not be cured, and cures the symptoms, not the disease.Both have significant difference.
Four, clinical experience
Received satisfied curative effect with Drug therapy cardiovascular disease of the present invention.Although the clinical symptoms of coronary heart disease, angina pectoris and heart infarction is a lot, and symptoms such as this clinical trial is selected common uncomfortable in chest, chest pain, nervously breathed hard, both hands refer to the fiber crops pain, vertigo and tinnitus, weak, insomnia.
1, the present invention is directed to the pathogenic factor scientific composition, adopt comprehensive many targets synchronization in blood, blood vessel, liver, lung, spleen, kidney, heart and whole circulation system, carry out comprehensively regulating by dissolving, mediation, cleaning, reparation, reach treating both the principal and secondary aspects of a disease, the five internal organs self function is recovered coordinate operation and is eliminated the cause of disease and finally reach rehabilitation.
2, multidigit medicine, big prescription have reserve strength, comprehensive conditioning to make that QI and blood is full, equilibrium between yin and yang.
3, the patient who cures is paid a return visit, discovery is recurred, and all is still living and in good health and goes up normal person's life.
If 4 do not belong to the patient that should not drink, adopt secondary every day, take medicated wine of the present invention 25ml/ time at every turn, medicine is borrowed the wine prestige, and wine helps the efficacy of a drug, and its curative effect can be better, and verify through the eligible patients.
Although 5 short term efficacies are very desirable,, also need pass through long-term clinical test because clinical time is limited.
Claims (3)
1. the Chinese medicine composition that is used for the treatment of cardiovascular and cerebrovascular disease is characterized in that the medicament of being made by weight by following bulk drugs:
Pericarpium Citri Reticulatae Viride 4-6, Radix Bupleuri 3-5, Rhizoma Cyperi 3-5, Radix Curcumae 4-6, Fructus Gardeniae 4-6, Radix Gentianae 4-6, Herba Solani Nigri 4-6, Ramulus Uncariae Cum Uncis 3-5, Radix Paeoniae Alba 8-10, Radix Polygoni Multiflori is processed 6-8, Radix Astragali 4-6, Ramulus Cinnamomi 3-5, Herba Pogostemonis 4-6, Semen Plantaginis 3-5, Semen Cuscutae 3-5, Radix Paeoniae Rubra 6-8, Rhizoma Chuanxiong 3-5, Radix Puerariae 6-8, Fructus Psoraleae 6-8, Radix Salviae Miltiorrhizae 4-6, Fructus Crataegi 8-10, Flos Carthami 4-6, fruit-rind of Chinese trichosanthes 8-10, Rhizoma Belamcandae 8-10, Cortex Moutan 6-8, Radix Rubiae 4-6, Radix Codonopsis 4-6, the Rhizoma Atractylodis Macrocephalae is processed 3-5, Poria 4-6, Endothelium Corneum Gigeriae Galli 3-5, Radix Linderae 3-5, Cortex Cinnamomi 3-5, Radix Scutellariae 6-8, Herba Ephedrae 3-5, Fructus Schisandrae Chinensis 2-4, Rhizoma Polygonati Odorati 4-6, the Radix Stemonae is processed 3-5, the Rhizoma Pinelliae is processed 3-5, Semen Sinapis Albae 3-5, Radix Peucedani 4-6, Lignum Santali Albi 6-8, Lignum Dalbergiae Odoriferae 6-8, Bulbus Allii Macrostemonis 4-6, Rhizoma Et Radix Notopterygii 3-5, Radix Clematidis 3-5, Caulis Piperis Kadsurae 3-5, Caulis Sinomenii 3-5, Herba Pyrolae 4-6, Herba Cistanches 4-6, Cornu Cervi Pantotrichum 2-3, Radix Morindae Officinalis 4-6, Fructus Lycii 3-5, Fructus Ligustri Lucidi 4-6, Fructus Corni 4-6, Rhizoma Anemarrhenae 3-5, Cortex Phellodendri 3-5, Semen Ziziphi Spinosae 4-6, Semen Platycladi 4-6, Radix Ilicis Pubescentis 6-8, Radix Polygalae is processed 3-5, Rhizoma Acori Graminei 4-6, Cortex Albiziae 6-8, Radix Achyranthis Bidentatae 4-6, Rhizoma Paridis 3-5, Fructus Jujubae 4-6, Rhizoma Alismatis 3-5, Herba Cynomorii 3-5, Fructus Broussonetiae 3-5, Hirudo 4-6, Cortex Lycii 3-5, dried Pheretima 6-8, Ganoderma 3-5, Rhizoma Smilacis Glabrae 3-5, Magnetitum powder 10-20, lobule Herba Lysimachiae 4-6.
2. the Chinese medicine composition that is used for the treatment of cardiovascular and cerebrovascular disease according to claim 1 is characterized in that described medicament is a said dosage form on any pharmaceutics.
3. the Chinese medicine composition that is used for the treatment of cardiovascular and cerebrovascular disease according to claim 1 and 2 is characterized in that described medicament is any one in powder, tablet, pill, capsule and the medicated wine.
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