CN103055111A - Traditional Chinese medicine composition for treating children's infantile malnutrition and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating children's infantile malnutrition and preparation method thereof Download PDF

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CN103055111A
CN103055111A CN2012105748823A CN201210574882A CN103055111A CN 103055111 A CN103055111 A CN 103055111A CN 2012105748823 A CN2012105748823 A CN 2012105748823A CN 201210574882 A CN201210574882 A CN 201210574882A CN 103055111 A CN103055111 A CN 103055111A
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chinese medicine
medicine composition
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bulbus allii
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CN103055111B (en
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孙鹏
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Anhui BBCA Pharmaceutical Co Ltd
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Anhui BBCA Pharmaceutical Co Ltd
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Abstract

The invention relates to a traditional Chinese medicine composition for treating children's infantile malnutrition and a preparation method thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicines by weight: 50 to 250 parts of fried cape jasmine fruit, 50 to 250 parts of saltcake, 50 to 250 parts of bitter apricot kernel, 50 to 250 parts of Chinese prickly ash and 10 to 100 parts of fistular onion stalk. Test results show that the traditional Chinese medicine composition provided by the invention has a therapeutic effect on patient children with a slim body, dysphoria, frequent crying, thirst and body heat caused by infantile malnutrition and the therapeutic effect is obviously superior to that of the prior art.

Description

A kind of Chinese medicine composition for the treatment of infantile malnutrition and preparation method thereof
Technical field
The present invention relates to Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of infantile malnutrition and preparation method thereof.
Background technology
Infantile malnutrition take god wither, the large muscle of emaciation and sallow complexion, brittle hair, tripe reveals, indigestion and loss of appetite loose stool is as the child disease of main manifestations.Be more common in 1~5 years old child.How because of eating and drinking without temperance, breast food improper feeding, impairing the spleen and stomach, transformation failure of spleen, undernutrition, QI and blood is precise and tiny can not moisten foster internal organs; Or because of diseases such as chronic diarrhea, chronic dysentery, Enterozoas, prolongedly do not heal, impairing the spleen and stomachs etc. cause a kind of chronic disease of malabsorption.
" infantile malnutrition " but in modern times has a marked difference with former said it " infantile malnutrition ", in the past because the restriction of living standard, people are usually hungry full uneven, not enough to children's's feeding, make in the taste and lose and living infantile malnutrition, how to be caused by malnutrition, namely be equivalent to " malnutrition " that doctor trained in Western medicine is said.And present raising along with people's living standard, and the only child increases recently, and the heads of a family lack again feeding knowledge, strengthen blindly nutrition, increased the weight of on the contrary the load of spleen fortune, injured QI of the spleen and stomach, it is long-pending middle burnt to stagnate, appetite is descended, and malnutrition is caused by nutrient imbalance so present infantile malnutrition is many.Two two kinds on the types that lose of clinical common deficiency of the spleen causing weakness of QI type and QI and blood.The primary disease onset is slow, course of disease delay, and the state of an illness is complicated, has a strong impact on children's upgrowth and development, very then threat to life.
At present, doctor trained in Western medicine is classified as malnutrition to infantile malnutrition, and clinical treatment mainly relies on vitimin supplement abundant food vitaminize B and intramuscular injection nandrolone phenylpropionate.The treatment power of doctor trained in Western medicine is being improved symptom, not from improve patient's body constitution, the treatment disease at all.
Not obvious for the western medicine effect, therefore, Chinese medicine preparation approved by the numerous heads of a family aspect the infantile malnutrition in treatment, as:
Be used for the treatment of gastropathy due to the Deficiency and coldness of spleen and stomach, number be 92111735.3 such as Chinese patent application, publication number is that the patent of invention of CN1085782 discloses a kind of prescriptions of Chinese medicine for the treatment of infantile malnutrition, have oral and two kinds of prescriptions of external application and usefulness, oral prescription is the compositions such as Pericarpium Citri Reticulatae Viride, the Radix Aucklandiae, the Rhizoma Atractylodis Macrocephalae, Chrysomyiame gacephala (Fab.), Radix Ginseng, Fructus Amomi, Fructus Hordei Germinatus, Placenta Hominis, Os Draconis, pollen, charcoal short, bristly hair or beard, Endothelium Corneum Gigeriae Galli, male power, Semen Coicis, the Radix Paeoniae Alba, Fructus Rubi, Semen Euryales, Os Tigris, Hunan Bufo siccus, Rhizomadioscoreae, Poria cum Radix Pini, the Radix Astragali, Jin Yingzi, Faeces Vespertilionis, Semen Arecae; Application compress prescriptions is: Radix Angelicae Sinensis, the Radix Aucklandiae, Mirabilitum, borneol, Rhizoma Chuanxiong, Folium Artemisiae Argyi, Indigo Naturalis, Flos Carthami, brill ground leads to muscle, Rhizoma Acori Graminei, mandarin orange leaf, practice hard the composition such as root bark.This prescription prescription is complicated, and the multi-flavor medicine is difficult the acquisition, and the flavour of a drug that have have certain toxicity, and the curative effect of this prescribed treatment infantile malnutrition and safety inspection are still waiting further checking.Except, also have dietetic therapy, massage, chiropractic, choose the Therapeutic Method such as infantile malnutrition, but all the course for the treatment of longer, onset is slow, the hordeolum therapy is comparatively painful disadvantage also.
CN95100102.7 relates to a kind of infantile malnutrition (being GANJI SAN) that is used for the treatment of, and also can be used for infantile anorexia, dyspepsia, agitation is cryed, it is not peaceful to sleep night, eating and drinking without temperance, eating cold and uncooked food excessively or because of medicine and the preparation technology of the diseases such as the abdominal distention due to being affected by the cold; catch cold; contract a cold, stomachache, diarrhoea.Health-care adhesive plaster for removing food stagnancy for children is mainly by Chinese medicine Fructus Gardeniae 30-40%, Flos Caryophylli 4%, Semen Armeniacae Amarum 13-23%, Radix orixae japonicae, Bulbus Allii Fistulosi, and ethyl hydroxybenzoate.
Other has experience side's GANJI SAN, is comprised of Flos Caryophylli, Semen Armeniacae Amarum, Pericarpium Zanthoxyli, Fructus Gardeniae (parched) equal portions, and it is lighter that this prescription is used for stagnant symptom, really effectively, if but stagnant heavierly just can not deal with problems.Infantile malnutrition is tangible breast food inner product, and the method for non-food stagnation removing can not be gone, and the method for food stagnation removing must with internal diabetes breast removing food stagnancy, combine with the admittance of sending down the abnormal ascending QI is stagnant.This prescription Flos Caryophylli, Fructus Piperis two a flavor tool warming spleen and stomach for dispelling cold, the usefulness of end asthenia cold abdominalgia, vomitting, having loose bowels, the food stagnation removing ability is not good enough.
The most prescription of existing compound Chinese medicinal preparation treatment infantile malnutrition is huge, and the many and a lot of medical materials of flavour of a drug are rareer, and oral preparations, and child administration gets up difficult.The minority prescription is little, but drug effect is looked into.
In order to overcome the shortcoming of prior art, the inventor has carried out a large amount of research, finally determines the present invention.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of infantile malnutrition.
Another object of the present invention provides the preparation method of described Chinese medicine composition.
A kind of infantile malnutrition Chinese medicine composition for the treatment of provided by the invention contains the Chinese medicine with following weight proportion: Fructus Gardeniae (parched) 50-250 part, Natrii Sulfas 50-250 part, Semen Armeniacae Amarum 50-250 part, Pericarpium Zanthoxyli 50-250 part, Bulbus Allii Fistulosi 10-100 part.
Preferably, described Chinese medicine composition contains the Chinese medicine of following weight portion: Fructus Gardeniae (parched) 150-200 part, Natrii Sulfas 150-200 part, Semen Armeniacae Amarum 150-200 part, Pericarpium Zanthoxyli 150-200 part, Bulbus Allii Fistulosi 50-75 part.
Further preferred, described Chinese medicine composition contains the Chinese medicine of following weight portion: 150 parts of Fructus Gardeniae (parched), 150 parts in Natrii Sulfas, 150 parts of Semen Armeniacae Amarums, 150 parts in Pericarpium Zanthoxyli, 50 parts of Bulbus Allii Fistulosi.
In the above-mentioned Chinese medicine composition:
Described Bulbus Allii Fistulosi is the bulb of the nearly root of liliaceous plant Herba Alii fistulosi Allium fistulosumL..
The present invention also provides the method for the above-mentioned Chinese medicine composition of preparation, and the method comprises the steps:
Take by weighing each composition according to proportioning, except Bulbus Allii Fistulosi, all the other four flavor Chinese medicine powders are broken into coarse powder, add the Bulbus Allii Fistulosi of smashing to pieces, pulverize, and oven drying at low temperature, and get final product.
In the said method:
The particle size range of described coarse powder is 850-250 μ m, and preferably, described particle size range is 350-500 μ m;
The particle size range of pulverizing after the Bulbus Allii Fistulosi that described adding is smashed to pieces is 150-500 μ m, is preferably 250-500 μ m;
Behind the oven drying at low temperature, also comprise the step of pulverizing, its particle size range is 250-500 μ m, is preferably 350-500 μ m.
The present invention also provides the preparation that contains above-mentioned Chinese medicine composition, and said preparation is made separately by Chinese medicine composition or is comprised of Chinese medicine composition and pharmaceutically acceptable carrier.
Described preparation is this area various dosage forms commonly used, such as powder, patch, ointment etc.
Described pharmaceutically acceptable carrier is glycerol, gelatin, starch, stearic acid, triethanolamine, cellulose derivative, polyvinyl alcohol, liquid Paraffin, ethyl hydroxybenzoate, vaseline, lanoline etc.
The present invention also provides the application of above-mentioned Chinese medicine composition in the medicine of preparation treatment infantile malnutrition, is mainly used in the face Huang Shaohua, and health is become thin, and agitation is crowed uneasy sleeping at night, inappetence, abdominal part distension, thirsty, body heat more.Red tongue, greasy fur, slippery and rapid pulse person.
Chinese medicine composition provided by the invention has the following advantages:
1, differential diagnosis in tcm is thought: the pathogenesis of infantile malnutrition mainly is taste imbalances, due to the deficiency of both QI and blood.In the Chinese medicine composition provided by the invention:
Fructus Gardeniae: bitter, cold, GUIXIN lung tri-jiao channel.The energy clearind deficient heat, diuresis, pathogenic fire purging, removing heat from blood, relieving restlessness;
Natrii Sulfas: salty, bitter, cold.Return stomach, large intestine channel, relieving constipation by purgation, moistening for dryness and softening hard mass.And keep and do not walk, without satiny fraud;
Semen Armeniacae Amarum: hardship, tepor is returned lung, large intestine channel, can fall apart and can fall, the effect of tool expelling pathogenic factors from muscles, loose wind, loosening bowel to relieve constipation, sending down the abnormal ascending QI, removing food stagnancy.
Pericarpium Zanthoxyli: hot, warm, return spleen, stomach, kidney channel, fragrant stomach invigorating, warming middle-JIAO, pain relieving.Bulbus Allii Fistulosi flavor fragrance activates yang into the stomach warp.
All medicines share, and play altogether hard masses softening and resolving, and consumer product dredge stasis, warming YANG help the merit of fortune spleen invigorating.Be in harmonious proportion with yellow wine during use and be affixed on the umbilicus eye, changed subsides in 24 hours, medicine can absorb by the umbilicus eye, stimulates the menstrual flow to pass through network and act on whole body, makes that taste are strong, QI and blood must be as a means of life.
2, the disclosed health-care adhesive plaster for removing food stagnancy for children of prior art such as CN95100102.7 is mainly by Chinese medicine Fructus Gardeniae 30-40%, Flos Caryophylli 4%, Semen Armeniacae Amarum 13-23%, Radix orixae japonicae, Bulbus Allii Fistulosi, and ethyl hydroxybenzoate.
Compared with prior art, difference of the present invention is: replaced Flos Caryophylli, Radix orixae japonicae with Natrii Sulfas, Pericarpium Zanthoxyli, characteristics for infantile malnutrition, the viewpoint of " the necessary intestinal stasis relieving of removing food stagnancy; intestinal stasis relieving is double heat clearing away often " is followed in clinical application, one side Pericarpium Zanthoxyli fragrance stomach invigorating, and the promotion gastric stagnates and digests, use on the other hand Natrii Sulfas can moisten the effect that to rush down so that stopping eating of can not the digesting method by the intestinal stasis relieving catharsis makes it become lower, get rid of external.
3, result of the test explanation: Chinese medicine composition provided by the invention is become thin at treatment infantile malnutrition health, and irritated crowing truly have curative effect during the infant of thirsty, body heat, and successful is better than prior art more.
The specific embodiment
Following examples are used for explanation the present invention, but are not used for limiting the scope of the invention.
Embodiment 1: the Chinese medicine composition for the treatment of infantile malnutrition
1, crude drug: Fructus Gardeniae (parched) 50kg, Natrii Sulfas 50kg, Semen Armeniacae Amarum 50kg, Pericarpium Zanthoxyli 50kg, Bulbus Allii Fistulosi 10kg.
2, preparation method:
1) the above five tastes, except Bulbus Allii Fistulosi, all the other Fructus Gardeniaes, Natrii Sulfas, Semen Armeniacae Amarum, Zanthoxyli Bungeani powder are broken into coarse powder, and particle diameter is 850 μ m;
2) add the Bulbus Allii Fistulosi smash to pieces, pulverize 500 μ m, then 60 ℃ of oven dry, be ground into again fine powder 350 μ m, mixing, and get final product.
Embodiment 2: the Chinese medicine composition for the treatment of infantile malnutrition
1, crude drug: Fructus Gardeniae 200g, Natrii Sulfas 200g, Semen Armeniacae Amarum 200g, Pericarpium Zanthoxyli 200g, Bulbus Allii Fistulosi 75g.
2, preparation method:
1) the above five tastes, except Bulbus Allii Fistulosi, all the other Fructus Gardeniaes, Natrii Sulfas, Semen Armeniacae Amarum, Zanthoxyli Bungeani powder are broken into coarse powder, and particle diameter is 500 μ m.
2) add the Bulbus Allii Fistulosi smash to pieces, pulverize 500 μ m, then 60 ℃ of oven dry, be ground into again fine powder 350 μ m, mixing, and get final product.
Embodiment 3: the Chinese medicine composition for the treatment of infantile malnutrition
1, crude drug: Fructus Gardeniae (stir-fry) 150kg, Natrii Sulfas 150kg, Semen Armeniacae Amarum 150kg, Pericarpium Zanthoxyli 150kg, Bulbus Allii Fistulosi 50kg.
2, preparation method:
1) the above five tastes, except Bulbus Allii Fistulosi, all the other Fructus Gardeniaes, Natrii Sulfas, Semen Armeniacae Amarum, Zanthoxyli Bungeani powder are broken into coarse powder, and particle diameter is 350 μ m.
2) add the Bulbus Allii Fistulosi smash to pieces, pulverize, cross 250 μ m, then 60 ℃ of oven dry, be ground into again fine powder 500 μ m, mixing, and get final product.
Embodiment 4: patch
1, the Chinese medicine composition 210g of crude drug: embodiment 1, glycerol 80g, stearic acid 120g, triethanolamine 30g, liquid Paraffin 180g, ethyl hydroxybenzoate 1.5g.
2, preparation method:
Take by weighing each composition according to proportioning, then glycerol, stearic acid, triethanolamine, liquid Paraffin, ethyl hydroxybenzoate, distilled water are put into same container, be heated to 85 ℃-90 ℃ and treat to dissolve fully, stopped heating is stirred to condensation, and get final product.
Comparative Examples 1: Chinese medicine composition
With reference to prior art, it consists of:
By Flos Caryophylli, Semen Armeniacae Amarum, Pericarpium Zanthoxyli, Fructus Gardeniae (parched) equal portions;
Its preparation method is with embodiment 1.
Comparative Examples 2: Chinese medicine composition
With reference to prior art CN95100102.7, its preparation method reference example 1, it is composed as follows:
Fructus Gardeniae 35%, Flos Caryophylli 4%, Semen Armeniacae Amarum 18%, Radix orixae japonicae 8%, Bulbus Allii Fistulosi 35%.
Experimental example 1: clinical effectiveness
Grandson, man, 18 months.During first visit as seen: emaciated physique, shallow complexion, abdominal flatulence, blue veins expose, hypotrichosis, spirit is irritated, feverish palms, night is sleeping not peaceful, has a liking for the food cold drinks and snachs, inappetence half a year, red tongue, greasy fur, deep-thready pulse.Stick the patch first quarter moon that the embodiment of the invention 4 provides.
During further consultation, grandson has thought diet, and tympanites disappears, and thirsty alleviation, and is continuous with accusing more behind the first quarter moon.
Experimental example 2: clinical trial
1, experimental subject: 122 routine infants, male 68 examples wherein, women 54 examples; Minimum 1 years old of age, maximum 6 years old, 2-3 year infant more.The course of disease is the shortest 1 month, and is the longest 6 months.The infant clinical manifestation mostly is emaciated physique, shallow complexion. the sparse tarnish of hair, and lethargy is is often cry and screamed, agitation, abdominal distention, inappetence, thirst and liking drink, body heat, it is undesired to defecate, and finger sucking is ground one's teeth in sleep.
2, Therapeutic Method: embodiment 1,2,3 groups, every group of 50 examples are prepared into patch note application embodiment 1 provided by the invention, 2,3 medicines that provide according to the method for embodiment 4, and to apply for two weeks be 1 course for the treatment of to note continuously, serve on 3 courses for the treatment of.1 group of Chinese medicine composition that uses Comparative Examples 1 to provide is provided, 2 groups of Chinese medicine compositions that use Comparative Examples 2 to provide are provided, two weeks were 1 course for the treatment of, serve on 3 courses for the treatment of.
3, curative effect determinate standard:
Cure: clinical symptom disappearance, diet is normal, and is in high spirits;
Take a turn for the better: clinical symptoms is improved, and appetite before takes an evident turn for the better;
Invalid: symptom, sign are without improvement before and after the treatment.
4, experimental result: see Table 1
Table 1: effect relatively
? Cure Take a turn for the better Invalid Total effective rate
1 group of embodiment 33(66%) 12(24%) 5(10%) 90%
2 groups of embodiment 34(68%) 13(26%) 3(6%) 94%
3 groups of embodiment 35(70%) 15(30%) 0(0%) 100%
Contrast 1 group 18(36%) 22(44%) 10(20%) 80%
Contrast 2 groups 20(40%) 24(48%) 6(12%) 88%
Table 1 result shows:
1 group of embodiment: clinical cure 33 examples (66%), 12 examples that take a turn for the better (24%), invalid 5 examples (10%), total effective rate 90.0%;
2 groups of embodiment: clinical cure 34 examples (68%), 13 examples that take a turn for the better (26%), invalid 3 examples (6%), total effective rate 92%;
3 groups of embodiment: clinical cure 35 examples (70%), 15 examples that take a turn for the better (30%), invalid 0 example (0%), total effective rate 100%;
Contrast 1 group: clinical cure 18 examples (36%), 22 examples that take a turn for the better (44%), invalid 10 examples (20%), total effective rate 80%;
Contrast 2 groups: clinical cure 20 examples (40%), 24 examples that take a turn for the better (48%), invalid 6 examples (12%), total effective rate 88%.
Aspect effective percentage, embodiment 1-3 group all reaches more than 90%, slightly is better than contrasting 1,2 group; Aspect cure rate, embodiment 1-3 group all reaches more than 65%, apparently higher than 40% of 1,2 group of contrast.
Result of the test explanation: Chinese medicine composition provided by the invention is become thin at treatment infantile malnutrition health, and irritated crowing truly have curative effect during the infant of thirsty, body heat, and successful is better than prior art more.
Although, above used general explanation, the specific embodiment and test, the present invention is described in detail, on basis of the present invention, can make some modifications or improvements it, and this will be apparent to those skilled in the art.Therefore, these modifications or improvements all belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.

Claims (10)

1. a Chinese medicine composition for the treatment of infantile malnutrition is characterized in that, described Chinese medicine composition contains the Chinese medicine with following weight proportion: Fructus Gardeniae (parched) 50-250 part, Natrii Sulfas 50-250 part, Semen Armeniacae Amarum 50-250 part, Pericarpium Zanthoxyli 50-250 part, Bulbus Allii Fistulosi 10-100 part.
2. Chinese medicine composition according to claim 1 is characterized in that, described Chinese medicine composition contains the Chinese medicine of following weight portion: Fructus Gardeniae (parched) 150-200 part, Natrii Sulfas 150-200 part, Semen Armeniacae Amarum 150-200 part, Pericarpium Zanthoxyli 150-200 part, Bulbus Allii Fistulosi 50-75 part.
3. Chinese medicine composition according to claim 1 is characterized in that, described Chinese medicine composition contains the Chinese medicine of following weight portion: 150 parts of Fructus Gardeniae (parched), 150 parts in Natrii Sulfas, 150 parts of Semen Armeniacae Amarums, 150 parts in Pericarpium Zanthoxyli, 50 parts of Bulbus Allii Fistulosi.
4. each described Chinese medicine composition is characterized in that according to claim 1-3, and described Bulbus Allii Fistulosi is the bulb of the nearly root of liliaceous plant Herba Alii fistulosi Allium fistulosumL..
5. a method for preparing each described Chinese medicine composition of claim 1-4 is characterized in that the method may further comprise the steps: take by weighing each composition according to proportioning, except Bulbus Allii Fistulosi, all the other four flavor Chinese medicine powders are broken into coarse powder, add the Bulbus Allii Fistulosi of smashing to pieces, pulverize, oven drying at low temperature, and get final product.
6. method according to claim 5 is characterized in that, the particle size range of described coarse powder is 850 μ m-250 μ m, and preferably, described particle size range is 350-500 μ m.
7. method according to claim 1 is characterized in that, the particle size range of pulverizing after the Bulbus Allii Fistulosi that described adding is smashed to pieces is 150-500 μ m, is preferably 250-500 μ m.
8. method according to claim 1 is characterized in that, behind the oven drying at low temperature, also comprises the step of pulverizing, and its particle size range is 250-500 μ m, is preferably 350-500 μ m.
9. contain the preparation that right requires each described Chinese medicine composition of 1-4, it is characterized in that said preparation is made separately by Chinese medicine composition or is comprised of Chinese medicine composition and pharmaceutically acceptable carrier.
10. each described Chinese medicine composition of claim 1-4 or preparation claimed in claim 9 application in the medicine of preparation treatment infantile malnutrition.
CN201210574882.3A 2012-12-26 2012-12-26 Traditional Chinese medicine composition for treating children's infantile malnutrition and preparation method thereof Active CN103055111B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104225548A (en) * 2014-09-26 2014-12-24 王育明 Formula and preparing method for infantile malnutrition external patch
CN104623224A (en) * 2015-01-06 2015-05-20 曹晓凤 Externally applied traditional Chinese medicine composition for treating infantile malnutrition and application thereof
CN113509493A (en) * 2020-04-09 2021-10-19 大连麦琪克生物技术有限公司 Bacteriostatic ointment for promoting wound healing and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1033740A (en) * 1988-07-30 1989-07-12 安徽省铜陵市长江路门诊部 Chinese medicine infantile malnutrition bag and preparation method thereof
CN1112837A (en) * 1995-01-06 1995-12-06 江西赣州制药厂 Health-care adhesive plaster for removing food stagnancy for children and the prepn. method
CN101791381A (en) * 2010-04-09 2010-08-04 单宏法 Externally-applied medicine for treating infantile malnutrition of infants

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1033740A (en) * 1988-07-30 1989-07-12 安徽省铜陵市长江路门诊部 Chinese medicine infantile malnutrition bag and preparation method thereof
CN1112837A (en) * 1995-01-06 1995-12-06 江西赣州制药厂 Health-care adhesive plaster for removing food stagnancy for children and the prepn. method
CN101791381A (en) * 2010-04-09 2010-08-04 单宏法 Externally-applied medicine for treating infantile malnutrition of infants

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104225548A (en) * 2014-09-26 2014-12-24 王育明 Formula and preparing method for infantile malnutrition external patch
CN104623224A (en) * 2015-01-06 2015-05-20 曹晓凤 Externally applied traditional Chinese medicine composition for treating infantile malnutrition and application thereof
CN113509493A (en) * 2020-04-09 2021-10-19 大连麦琪克生物技术有限公司 Bacteriostatic ointment for promoting wound healing and preparation method thereof
CN113509493B (en) * 2020-04-09 2024-01-30 大连麦琪克生物技术有限公司 Antibacterial ointment for promoting wound healing and preparation method thereof

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