CN101829312A - Medicament for treating rheumatoid arthritis and preparation method thereof - Google Patents
Medicament for treating rheumatoid arthritis and preparation method thereof Download PDFInfo
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- CN101829312A CN101829312A CN201010179681A CN201010179681A CN101829312A CN 101829312 A CN101829312 A CN 101829312A CN 201010179681 A CN201010179681 A CN 201010179681A CN 201010179681 A CN201010179681 A CN 201010179681A CN 101829312 A CN101829312 A CN 101829312A
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Abstract
The invention discloses a medicament for treating rheumatoid arthritis, which is prepared by using bixie sevenlobed yam rhizome, Fukuai, ginger, white atractylodes rhizome, Chinese ephedra, raw liquorice, rhizoma anemarrhenae, white paeony root, cassia twig, rhizoma alismatis and divaricate saposhnikovia root as raw materials. The medicament can be prepared into multiple preparations used clinically, and has better treatment effect on rheumatoid arthritis, no toxic and side effects and safe and reliable clinical application.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of rheumatoid arthritis, specially referring to a kind of is the medicine of the treatment rheumatoid arthritis of feedstock production with the Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Background technology
Rheumatoid arthritis is a kind of chronic systemic autoimmune disease.It is feature usually with the articular synovitis.In recent years, along with the change of people life style and dietary structure, patient with rheumatoid arthritis is the trend that increases year by year, and synovitis is outbreak repeatedly lastingly, the destruction that can cause intraarticular cartilage and bone, and joint function disturbance, in addition maimed.The vasculitis pathological changes is involved each organ of whole body, so primary disease is called rheumatoid disease again.
The medicine of rheumatoid arthritis is more at present, but does not still have specific short so far, still stays in the treatment to inflammation and sequela, takes Comprehensive Treatment, and most of patients all can obtain certain curative effect.The medicine of treatment rheumatoid arthritis is more, these medicines have different effects to rheumatoid arthritis, be the disappearance of being devoted to surface symptoms mostly, can not treating both the principal and secondary aspects of a disease, can not eliminate recurrence, needs of patients is taken for a long time, and the side effect that a large amount of use produced of the medicine that has also can not be ignored.Radix Tripterygii Wilfordii is the medicine with good efficacy that goes out through domestic experimentation for many years, but this medicine can produce female irregular menstruation and menolipsis, and mankind spermatozoon quantity reduces, erythra, leukocyte and thrombocytopenia, abdominal pain diarrhea etc.Present treatment rheumatism relatively more commonly used be that collateral dredging is opened the fewer pure Chinese medicines of some side effect such as numbness sheet, but rheumatoid will be stablized the state of an illness after just curing for a long time, in taking the various kinds of drug process, also is very important to the injury of stomach.
Summary of the invention
The present invention aims to provide the medicine of the treatment rheumatoid arthritis that a kind of therapeutic effect is good, cost is low, side effect is less.
The preparation method that this medicine is provided is another goal of the invention of the present invention.
Medicine of the present invention is to be made by following quality proportion raw material:
Rhizoma Dioscoreae Septemlobae 20-35 Radix Aconiti Lateralis Preparata 15-30 Rhizoma Zingiberis Recens 5-15
Rhizoma Atractylodis Macrocephalae 5-15 Herba Ephedrae 5-15 Radix Glycyrrhizae 5-15
Rhizoma Anemarrhenae 5-15 Radix Paeoniae Alba 5-15 Ramulus Cinnamomi 8-15
Rhizoma Alismatis 5-15 Radix Saposhnikoviae 5-15.
The further quality proportioning of medicine each component of the present invention is:
Rhizoma Dioscoreae Septemlobae 30 Radix Aconiti Lateralis Preparata 20 Rhizoma Zingiberis Recenss 9
The Rhizoma Atractylodis Macrocephalae 9 Herba Ephedraes 9 Radix Glycyrrhizae 9
The Rhizoma Anemarrhenae 9 Radix Paeoniae Albas 9 Ramulus Cinnamomi 12
Rhizoma Alismatis 12 Radix Saposhnikoviaes 9.
The concrete preparation method of medicine of the present invention is as follows:
Getting above-mentioned mass fraction Chinese medicine mixes, the clear water that adds the 150-300 weight portion, 0.5-2.5 at a simmer hour, after frying in shallow oil 3 times repeatedly, take out medicinal residues, marmite is put in 3 medicinal liquid mixing fried in shallow oil 2-4 hour, medicinal liquid is condensed into the thick paste shape, add conventional adjuvant then, make clinical tablet commonly used, capsule, pill, granule, powder, injection or unguentum.
Motherland's medical science claims that primary disease is " arthromyodynia "." element is asked a numbness opinion piece of writing " said: " wind, cold, wet three gas are assorted to closing be numbness also, its migratory BI-syndrome caused mainly by pathogenic wind, BI-syndrome caused mainly by pathogenic cold being called painful BI, the BI syndrome caused mainly by pathogenic dampness being called fixed BI." and " Medical Treasures of the Golden Chamber " claims that primary disease is " severe and migratory arthralgia ", meaning i.e. pain is gone through hundred joints all over, is the very person of arthralgia aggravated by cold.Exopathogen invasion and attack meridians, the QI and blood impatency can not pass unimpeded, cause joint etc. locate to occur acid, bitterly, fiber crops, heavily reach symptom such as joint stuffiness.Also have because of the health intenseness of heat, the damp of having a cold again, strongly fragrant and heat-transformation is sent out and is the pyretic arthralgia person, so arthromyodynia has the branch of arthralgia due to cold and pyretic arthralgia again.
The pharmacology of each medicine of the present invention is:
Ramulus Cinnamomi: Xin Gan, temperature.Go into bladder, the heart, lung three warps.The diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.Control exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea.
The Radix Paeoniae Alba: cold nature, bitter in the mouth, acid.The suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat are used to have a headache.
The Rhizoma Anemarrhenae: cold in nature, bitter in the mouth, sweet.Clearing away heat-fire promotes the production of body fluid and moisturizes.Be used for that fever caused by exogenous pathogenic factors, lung-heat type cough, osteopyrexia and fever, interior-heat are quenched one's thirst, dryness of the intestine, constipation.
Radix Glycyrrhizae: property is flat, sweet in the mouth.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, cushion toxicity.
Herba Ephedrae: warm in nature, acrid in the mouth, little hardship.The diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.Be used for anemofrigid cold, uncomfortable in chestly breath with cough, edema due to wind pathogen edema, bronchial asthma.
The Rhizoma Atractylodis Macrocephalae: warm in nature, bitter in the mouth, sweet.Invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.Be used for that insufficiency of the spleen lack of appetite, abdominal distention are had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix Saposhnikoviae: warm in nature, hide sweet, hot.Inducing diaphoresis to dispel wind wins and wets, relieving convulsion.Be used for headache due to common cold, rheumatic arthralgia, spasm of the limbs, rheumatism pruritus, tetanus.
Side's epheday intermedia adds the Rhizoma Atractylodis Macrocephalae, and the exterior syndrome of all numbness is separated from antiperspirant, and two medicines match, the unlikely antiperspirant of crossing; The attached Radix Saposhnikoviae in osmanthus is harmonious, the energy warming the meridian for promoting the flow of YANG QI; The slow pain of Radix Paeoniae Rhizoma Anemarrhenae yin nourishing; During Rhizoma Zingiberis Recens Radix Glycyrrhizae and battalion transfer, play the effect of collateral dredging migratory arthralgia altogether.Can fundamentally solve the rheumatoid arthritis problem like this, each component is complementary collaborative in the prescription, and dialectical treatment makes this medicine to rheumatoid arthritis good curative effect be arranged.
During treatment, this medicine was taken for three times morning, noon, the late branch.
Use clinical drug treatment rheumatoid arthritis people 137 examples of the present invention, the result shows, cures 89 examples, cure rate 65%, 31 examples that take a turn for the better to some extent, total effective rate 87.6%.Clinical test results proves that effect of drugs of the present invention is obvious, definite, and has no side effect, and clinical practice is safe and reliable.
The specific embodiment
Below in conjunction with embodiment the present invention is described in further detail, but does not constitute any limitation of the invention.
Embodiment 1
Prepare raw material according to following weight:
Rhizoma Dioscoreae Septemlobae 3kg, Radix Aconiti Lateralis Preparata 2kg, Rhizoma Zingiberis Recens 0.9kg, Rhizoma Atractylodis Macrocephalae 0.9kg, Herba Ephedrae 0.9kg, Radix Glycyrrhizae 0.9kg, Rhizoma Anemarrhenae 0.9kg, Radix Paeoniae Alba 0.9kg, Ramulus Cinnamomi 1.2kg, Rhizoma Alismatis 1.2kg, Radix Saposhnikoviae 0.9.
Above-mentioned raw materials is mixed, adds the clear water of 30kg weight portion, 1.5 hours at a simmer, fry in shallow oil 3 times repeatedly after, take out medicinal residues, marmite is put in 3 medicinal liquid mixing fried in shallow oil 4 hours, medicinal liquid is condensed into the thick paste shape, add refined honey then, mix homogeneously is made big honeyed pills, gets finished product after the packing.
Embodiment 2
Prepare raw material according to following weight:
Rhizoma Dioscoreae Septemlobae 3kg, Radix Aconiti Lateralis Preparata 2kg, Rhizoma Zingiberis Recens 0.9kg, Rhizoma Atractylodis Macrocephalae 0.9kg, Herba Ephedrae 0.9kg, Radix Glycyrrhizae 0.9kg, Rhizoma Anemarrhenae 0.9kg, Radix Paeoniae Alba 0.9kg, Ramulus Cinnamomi 1.2kg, Rhizoma Alismatis 1.2kg, Radix Saposhnikoviae 0.9.
Above-mentioned raw materials is mixed, adds the clear water of 40kg weight portion, 1 hour at a simmer, fry in shallow oil 3 times repeatedly after, take out medicinal residues, marmite is put in 3 medicinal liquid mixing fried in shallow oil 3 hours, medicinal liquid is condensed into the thick paste shape, with the oven dry of thick paste shape medicine, the grinding, encapsulated of gained, sterilization gets finished product after the packing then.
Claims (3)
1. medicine for the treatment of rheumatoid arthritis is characterized in that described medicine is the medicament of being made by following quality proportion raw material:
Rhizoma Dioscoreae Septemlobae 20-35 Radix Aconiti Lateralis Preparata 15-30 Rhizoma Zingiberis Recens 5-15
Rhizoma Atractylodis Macrocephalae 5-15 Herba Ephedrae 5-15 Radix Glycyrrhizae 5-15
Rhizoma Anemarrhenae 5-15 Radix Paeoniae Alba 5-15 Ramulus Cinnamomi 8-15
Rhizoma Alismatis 5-15 Radix Saposhnikoviae 5-15.
2. the medicine of treatment rheumatoid arthritis according to claim 1 is characterized in that described medicine is the medicament of being made by following quality proportion raw material:
Rhizoma Dioscoreae Septemlobae 30 Radix Aconiti Lateralis Preparata 20 Rhizoma Zingiberis Recenss 9
The Rhizoma Atractylodis Macrocephalae 9 Herba Ephedraes 9 Radix Glycyrrhizae 9
The Rhizoma Anemarrhenae 9 Radix Paeoniae Albas 9 Ramulus Cinnamomi 12
Rhizoma Alismatis 12 Radix Saposhnikoviaes 9.
3. the preparation method of treatment medicine for treating rheumatoid arthritis according to claim 1 and 2, it is characterized in that the Chinese medicine of above-mentioned mass fraction is mixed, the clear water that adds the 200-400 weight portion, 0.5-1.5 at a simmer hour, fry in shallow oil 3 times repeatedly after, take out medicinal residues, marmite is put in 3 medicinal liquid mixing to be fried in shallow oil 2-4 hour, medicinal liquid is condensed into the thick paste shape, adds conventional adjuvant then, make tablet, capsule, pill, granule, powder, injection or the unguentum of clinical use.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010179681A CN101829312A (en) | 2010-05-18 | 2010-05-18 | Medicament for treating rheumatoid arthritis and preparation method thereof |
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| CN201010179681A CN101829312A (en) | 2010-05-18 | 2010-05-18 | Medicament for treating rheumatoid arthritis and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102091311A (en) * | 2011-01-26 | 2011-06-15 | 蚌埠丰原涂山制药有限公司 | Traditional Chinese medicinal composition for treating rheumatoid arthritis and preparation method thereof |
| CN102949684A (en) * | 2011-08-18 | 2013-03-06 | 张志通 | Medicine formula for treating rheumatoid arthritis |
-
2010
- 2010-05-18 CN CN201010179681A patent/CN101829312A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102091311A (en) * | 2011-01-26 | 2011-06-15 | 蚌埠丰原涂山制药有限公司 | Traditional Chinese medicinal composition for treating rheumatoid arthritis and preparation method thereof |
| CN102091311B (en) * | 2011-01-26 | 2012-07-04 | 蚌埠丰原涂山制药有限公司 | Traditional Chinese medicinal composition for treating rheumatoid arthritis and preparation method thereof |
| CN102949684A (en) * | 2011-08-18 | 2013-03-06 | 张志通 | Medicine formula for treating rheumatoid arthritis |
| CN102949684B (en) * | 2011-08-18 | 2014-04-02 | 张志通 | Medicine formula for treating rheumatoid arthritis |
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Open date: 20100915 |