CN102949684B - Medicine formula for treating rheumatoid arthritis - Google Patents
Medicine formula for treating rheumatoid arthritis Download PDFInfo
- Publication number
- CN102949684B CN102949684B CN201110250094.4A CN201110250094A CN102949684B CN 102949684 B CN102949684 B CN 102949684B CN 201110250094 A CN201110250094 A CN 201110250094A CN 102949684 B CN102949684 B CN 102949684B
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- China
- Prior art keywords
- radix
- medicines
- rhizoma
- treatment
- rheumatoid arthritis
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- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 22
- 229940079593 drug Drugs 0.000 title claims abstract description 8
- 206010039073 rheumatoid arthritis Diseases 0.000 title claims abstract description 8
- 241000903946 Clematidis Species 0.000 claims abstract description 4
- 239000006187 pill Substances 0.000 claims abstract description 4
- 210000000582 semen Anatomy 0.000 claims abstract description 4
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 3
- 241000271039 Agkistrodon Species 0.000 claims description 3
- 239000002994 raw material Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 4
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 244000306301 Caesalpinia sappan Species 0.000 abstract 1
- 235000015162 Caesalpinia sappan Nutrition 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 241000218671 Ephedra Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000010254 Jasminum officinale Nutrition 0.000 abstract 1
- 240000005385 Jasminum sambac Species 0.000 abstract 1
- 241000488974 Loranthus Species 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 241001180876 Saposhnikovia Species 0.000 abstract 1
- 240000004534 Scutellaria baicalensis Species 0.000 abstract 1
- 235000017089 Scutellaria baicalensis Nutrition 0.000 abstract 1
- 241000271897 Viperidae Species 0.000 abstract 1
- 244000273928 Zingiber officinale Species 0.000 abstract 1
- 235000006886 Zingiber officinale Nutrition 0.000 abstract 1
- 235000008397 ginger Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 230000003071 parasitic effect Effects 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 208000006820 Arthralgia Diseases 0.000 description 2
- 230000001506 immunosuppresive effect Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000008469 Peptic Ulcer Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- CKMXBZGNNVIXHC-UHFFFAOYSA-L ammonium magnesium phosphate hexahydrate Chemical compound [NH4+].O.O.O.O.O.O.[Mg+2].[O-]P([O-])([O-])=O CKMXBZGNNVIXHC-UHFFFAOYSA-L 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 229910052567 struvite Inorganic materials 0.000 description 1
- 210000001258 synovial membrane Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicine formula for treating rheumatoid arthritis. The formula comprises the following components according to a unit of kilogram: 20g of sappanwood, 20g of scutellaria baicalensis, 15g of radix bupleuri, 15g of honeysuckle stem, 20g of radix clematidis, 20g of raw liquorice, 10g of cassia twig, 20g of radix paeoniae alba, 20g of rhizoma anemarrhenae, 10g of ephedra, 15g of jasmine, 8g of ginger, 30g of semen coicis, 20g of rhizoma atractylodis macrocephalae, 30g of rhizoma dioscoreae, 20g of rehmannia root, 15g of divaricate saposhnikovia root, 15g of mangnolia officinalis, 15g of parasitic loranthus and 10g of long-noded pit viper. The medicines are pulverized into 80-100 meshes of fine powder according to the proportion; the medicines are manufactured to make pills of 10g, 2 pills are orally taken for one time and three time for one day; the dosage of the medicines for 15 days is used as a first course of treatment; and the medicines are orally taken for two courses of treatment, so that the good curative effect is generally achieved.
Description
Affiliated technical field
The present invention relates to a kind of medicament composing prescription for the treatment of rheumatoid arthritis, i.e. a kind of medicament composing prescription that utilizes Chinese crude drug treatment rheumatoid arthritis.
Background technology
Rheumatoid arthritis belongs to the category of motherland's medical science pyretic arthralgia, and it is how obstructed in meridians, joint, QI and blood stasis by wind, wet, all evil harmonies of heat that ancients think, so that local red and swollen scorching hot, and arthralgia can not be bent and stretched and ill.Modern medicine is thought: it is that the struvite autoimmune disease of chronic systematicness that synovium of joint is main target tissue is take in a kind of infringement.The main little joint of brothers of invading, other organ or tissue also can get involved, and this disease does not have good drug treatment at present, and patient can not walk, very painful.
Summary of the invention
In order to cure this disease, alleviate patient suffering, the invention provides a kind of medicament composing prescription of highly effective treatment rheumatoid arthritis.
Plan method for the treatment of of the present invention is: expelling wind and removing dampness, warming the meridian a surname numbness, nourishing YIN and clearing away heat.
Prescription of the present invention is (in grams): Lignum Sappan 20, Radix Scutellariae 20, Radix Bupleuri 15, Caulis Lonicerae 15, Radix Clematidis 20, Radix Glycyrrhizae 20, Ramulus Cinnamomi 10, the Radix Paeoniae Alba 20, the Rhizoma Anemarrhenae 20, Herba Ephedrae 10, Fructus Gardeniae 15, Rhizoma Zingiberis Recens 8, SEMEN COICIS 30, the Rhizoma Atractylodis Macrocephalae 20, Rhizoma Dioscoreae 30, the Radix Rehmanniae 20, Radix Saposhnikoviae 15, Cortex Magnoliae Officinalis 15, Herba Taxilli 15, Agkistrodon 10.
Said medicine is mixed in proportion and is pulverized as 80-100 object smalls, make the pill of 10 grammes per square metres, 2 balls, take for three times on the one, within 15 days, are a course for the treatment of, take 2 courses for the treatment of, can receive good curative effect.
In side: Lignum Sappan, Radix Clematidis, Ramulus Cinnamomi, Herba Ephedrae, Agkistrodon all have dredge the meridian passage, the effect of activating stagnated YANG, wherein, Lignum Sappan has immunosuppressive action according to modern study.Radix Bupleuri depressed liver-energy dispersing and QI regulating, the Cortex Magnoliae Officinalis circulation of qi promoting painful abdominal mass that disappears; The Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae strengthening spleen, tonifying kidney; Radix Saposhnikoviae, Herba Taxilli expelling wind and removing dampness; SEMEN COICIS promoting diuresis to eliminate damp pathogen; Rhizoma Zingiberis Recens warming middle-JIAO to arrest vomiting; The Rhizoma Atractylodis Macrocephalae, the Rhizoma Anemarrhenae, Radix Rehmanniae nourishing YIN and clearing away heat; Radix Scutellariae, Radix Glycyrrhizae, Fructus Gardeniae clearing away heat-fire reason wet, and wherein, Radix Scutellariae, Radix Glycyrrhizae all have immunosuppressive action according to modern study.
This beneficial effect of the invention is: utilize the Chinese herbal medicine of motherland's traditional medicine to carry out reasonable compatibility, treatment cost is lower, and side effect is less, and therapeutic effect is remarkable.
The specific embodiment
The effectiveness of said medicine is now described with 60 routine patients of clinical observation, 60 routine patients are completely with reference to the Americanism damp disease RA of association in 1987 diagnostic criteria, get rid of Liver and kidney patient, hypertension, diabetes, Peptic Ulcers and the medicine factor that affects the treatment and observe, wherein, male 36 examples, female's 24 examples, the shortest person of the course of disease 1 year, elder 20 years, patient, by 2 balls of said medicine, takes for three times on the one, take 2 courses for the treatment of, in 60 routine patients, cure 19 examples as a result, effective 23 examples, 15 examples take a turn for the better, invalid 3 examples, total effective rate 95%.
Claims (1)
1. a medicine for the treatment of rheumatoid arthritis, it is characterized in that described medicine made by the crude drug of following weight portion: Lignum Sappan 20, Radix Scutellariae 20, Radix Bupleuri 15, Caulis Lonicerae 15, Radix Clematidis 20, Radix Glycyrrhizae 20, Ramulus Cinnamomi 10, the Radix Paeoniae Alba 20, the Rhizoma Anemarrhenae 20, Herba Ephedrae 10, Fructus Gardeniae 15, Rhizoma Zingiberis Recens 8, SEMEN COICIS 30, the Rhizoma Atractylodis Macrocephalae 20, Rhizoma Dioscoreae 30, the Radix Rehmanniae 20, Radix Saposhnikoviae 15, Cortex Magnoliae Officinalis 15, Herba Taxilli 15, Agkistrodon 10, above-mentioned raw materials medicine is mixed in proportion and is pulverized as 80-100 object smalls, make the pill of 10 grammes per square metres.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110250094.4A CN102949684B (en) | 2011-08-18 | 2011-08-18 | Medicine formula for treating rheumatoid arthritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110250094.4A CN102949684B (en) | 2011-08-18 | 2011-08-18 | Medicine formula for treating rheumatoid arthritis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102949684A CN102949684A (en) | 2013-03-06 |
| CN102949684B true CN102949684B (en) | 2014-04-02 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110250094.4A Expired - Fee Related CN102949684B (en) | 2011-08-18 | 2011-08-18 | Medicine formula for treating rheumatoid arthritis |
Country Status (1)
| Country | Link |
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| CN (1) | CN102949684B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105833117A (en) * | 2016-05-17 | 2016-08-10 | 刘喜德 | Traditional Chinese medicine composition for treating rheumatoid arthritis |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101357168A (en) * | 2008-09-16 | 2009-02-04 | 朱惠芬 | Medicinal wine for treating rheumatic arthritis |
| CN101496849A (en) * | 2008-01-31 | 2009-08-05 | 邹方昕 | Chinese medicine preparation for treating atrophic arthritis |
| CN101543620A (en) * | 2008-03-28 | 2009-09-30 | 北京汉潮大成科技孵化器有限公司 | Traditional Chinese medicine preparation for treating rheumatoid arthritis |
| CN101829312A (en) * | 2010-05-18 | 2010-09-15 | 山西省屯留县科技情报服务中心 | Medicament for treating rheumatoid arthritis and preparation method thereof |
-
2011
- 2011-08-18 CN CN201110250094.4A patent/CN102949684B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101496849A (en) * | 2008-01-31 | 2009-08-05 | 邹方昕 | Chinese medicine preparation for treating atrophic arthritis |
| CN101543620A (en) * | 2008-03-28 | 2009-09-30 | 北京汉潮大成科技孵化器有限公司 | Traditional Chinese medicine preparation for treating rheumatoid arthritis |
| CN101357168A (en) * | 2008-09-16 | 2009-02-04 | 朱惠芬 | Medicinal wine for treating rheumatic arthritis |
| CN101829312A (en) * | 2010-05-18 | 2010-09-15 | 山西省屯留县科技情报服务中心 | Medicament for treating rheumatoid arthritis and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN102949684A (en) | 2013-03-06 |
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Address after: 734200 No.11, group 9, kangzhai village, Xinhua Town, Linze County, Zhangye City, Gansu Province Patentee after: Zhang Zhisheng Address before: 734200 Linze County, Gansu Province, Xinhua Township, Kang Village 9 Club Patentee before: Zhang Zhitong |
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| TR01 | Transfer of patent right |
Effective date of registration: 20210416 Address after: Lianhuan pharmaceutical, building E5, Jiangsu life science and Technology Innovation Park, No.9, Weidi Road, Xianlin street, Qixia District, Nanjing City, Jiangsu Province Patentee after: Nanjing Lianzhi Pharmaceutical Technology Co.,Ltd. Address before: 734200 No.11, group 9, kangzhai village, Xinhua Town, Linze County, Zhangye City, Gansu Province Patentee before: Zhang Zhisheng |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140402 |
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| CF01 | Termination of patent right due to non-payment of annual fee |