CN104667243A - Traditional Chinese medicament for treating ulcerative colitis - Google Patents

Traditional Chinese medicament for treating ulcerative colitis Download PDF

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Publication number
CN104667243A
CN104667243A CN201510118389.4A CN201510118389A CN104667243A CN 104667243 A CN104667243 A CN 104667243A CN 201510118389 A CN201510118389 A CN 201510118389A CN 104667243 A CN104667243 A CN 104667243A
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parts
radix
ulcerative colitis
traditional chinese
rhizoma
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CN201510118389.4A
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孙杰
黄爱玲
王美娜
刘弘强
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Abstract

The invention relates to the field of medicinal formula, in particular to a traditional Chinese medicament for treating ulcerative colitis. The traditional Chinese medicament is prepared from the following raw medicinal materials in parts by weight: 9 to 12 parts of pinellia ternate, 6 to 9 parts of scutellaria baicalensis, 2 to 5 parts of coptis chinensis, 3 to 9 parts of dry ginger, 6 to 9 parts of codonopsis pilosula, 6 to 9 parts of liquorice, 20 to 30 parts of patrinia, 15 to 60 parts of aconitum carmichaelii, 9 to 12 parts of angelica sinensis, 30 to 50 parts of white paeony root, 6 to 9 parts of Chinese thorowax root, 3 to 10 parts of mangnolia officinalis, 6 to 9 parts of Chinese date, 15 to 30 parts of semen coicis, 3 to 9 parts of rhizoma atractylodis, 3 to 6 parts of betelnut piece, and 6 to 9 parts of tangerine peel. The raw medicinal materials are decocted by adding water; a filtrate is obtained by deslagging. The traditional Chinese medicament is low in cost, has the effects of regulating qi, smoothing qi, activating blood, expelling dampness, clearing dry heat, warming and nourishing the spleen and the kidneys, discharging liver, relieving depression, lifting yang-qi, resisting bacteria, resisting ulcer, purging fire, removing toxic substance, diminishing inflammation and relieving pain, and also has the functions of restoring yang, invigorating pulse-beat, adjusting gastric bowel movement, promoting the cure of an ulcerative surface, and effectively treating the ulcerative colitis.

Description

The Chinese medicine for the treatment of ulcerative colitis
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine for the treatment of ulcerative colitis.
Background technology
As everyone knows, the treatment of ulcerative colitis is a universally acknowledged difficult problem, and major part adopts western medicine therapy, and be generally that injection of antibiotics and medicine add hormone clysmata, severe patient will coordinate operative treatment or removal of lesions.The toxic and side effects of its medicine, the perform the operation functional lesion and misery that cause, patient is difficult to stand, and the state of an illness is also difficult to radical cure, more difficultly on treatment cost bears.
Summary of the invention
Object of the present invention is exactly to overcome above-mentioned existing technical deficiency, provides the Chinese medicine of the treatment ulcerative colitis that cost is low, toxic and side effects is little, therapeutic effect is good.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine for the treatment of ulcerative colitis, it is characterized in that being made up of the crude drug of following weight portion: Rhizoma Pinelliae 9-12, Radix Scutellariae 6-9, Rhizoma Coptidis 2-5, Rhizoma Zingiberis 3-9, Radix Codonopsis 6-9, Radix Glycyrrhizae 6-9, Herba Patriniae 20-30, Radix Aconiti Lateralis Preparata 15-60, Radix Angelicae Sinensis 9-12, Radix Paeoniae Alba 30-50, Radix Bupleuri 6-9, Cortex Magnoliae Officinalis 3-10, Fructus Jujubae 6-9, Semen Coicis 15-30, Rhizoma Atractylodis 3-9, Semen Arecae sheet 3-6, Pericarpium Citri Reticulatae 6-9, adds water above-mentioned raw materials medicine and decocts, filtrate of removing slag to obtain.
The invention has the beneficial effects as follows, cost is low, have regulating QI, regulate the flow of vital energy, invigorate blood circulation, wet clearly, clearing away dryness is warm, effect that warming and recuperating the spleen and kidney, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy, antibacterial antiulcer, eliminating fire and detoxication, antiinflammatory relieve the pain, also have recuperating depleted YANG to promote blood circulation, adjust gastrointestinal motility, promote the function of ulcer surface healing, effectively treatment ulcerative colitis.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
Adopt the Rhizoma Pinelliae, Radix Scutellariae, Rhizoma Coptidis, Rhizoma Zingiberis, Radix Codonopsis, Radix Glycyrrhizae, Herba Patriniae, Radix Aconiti Lateralis Preparata, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Bupleuri, Cortex Magnoliae Officinalis, Fructus Jujubae, Semen Coicis, Rhizoma Atractylodis, Semen Arecae sheet, Pericarpium Citri Reticulatae, for raw material is prepared from, adds water above-mentioned raw materials medicine and decocts, filtrate of removing slag to obtain.Its component (weight portion) is often paid as the Rhizoma Pinelliae 12, Radix Scutellariae 9, Rhizoma Coptidis 5, Rhizoma Zingiberis 9, Radix Codonopsis 9, Radix Glycyrrhizae 9, Herba Patriniae 30, Radix Aconiti Lateralis Preparata 60, Radix Angelicae Sinensis 12, the Radix Paeoniae Alba 50, Radix Bupleuri 9, Cortex Magnoliae Officinalis 10, Fructus Jujubae 9, Semen Coicis 30, Rhizoma Atractylodis 9, Semen Arecae sheet 6, Pericarpium Citri Reticulatae 6.Getting above-mentioned 20 taste raw material gross weights is 216 grams, and add water about 1100ml, at room temperature soaks 3-4 hour, decoct to 40 minutes, remove slag to obtain filtrate 200ml, and medicinal residues add water 300ml again, decoct 30-40 minute, remove slag to obtain filtrate 100ml, is total to obtain about 300ml medicine juice, i.e. obtained decoction of the present invention, load in sterile glass vials, seal bottle cap is for subsequent use, and every day 1 dose point 2 times is oral, and 2 hours after meal oral.15 days is a course for the treatment of, takes and stops 2 days 1 course for the treatment of, then take next course for the treatment of, generally applies two courses for the treatment of.
Rhizoma Pinelliae dissolving lump and resolving mass of the present invention, coordination of cold and heat, there is effect of antiulcer.Radix Scutellariae, Rhizoma Coptidis have eliminating fire and detoxication, effect of antibacterial antiulcer.Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation.Radix Codonopsis Gastrointestinal motility adjustment, QI invigorating.Fructus Jujubae, Radix Glycyrrhizae spleen reinforcing tonify deficiency, invigorating the spleen and regulating the stomach, QI invigorating profit cardiopulmonary.Herba Patriniae, Radix Aconiti Lateralis Preparata have recuperating depleted YANG and rescuing the patient from collapse, evacuation of pus antiinflammatory, mend effect that fire is supporing yang, wet by wind and cold heresy, promote ulcer surface reparation.Radix Angelicae Sinensis, the Radix Paeoniae Alba are enriched blood and are invigorated blood circulation, intestine moistening, suppressing the hyperactive liver pain relieving, have bacteriostasis efficacy.Radix Bupleuri has effect that is soothing the liver, elevate a turnable ladder yang-energy.Cortex Magnoliae Officinalis, Semen Coicis, Semen Arecae sheet have circulation of qi promoting, removing food stagnancy, spleen invigorating, antidiarrheal, degermation.Pericarpium Citri Reticulatae main effect is regulated the flow of vital energy.Rhizoma Atractylodis are used for antibacterial antiulcer.
The each raw material of the present invention also can the embodiment that mixes of ratio (weight portion) listed by according to the form below realize.Its processing technique is identical with embodiment 1.
Embodiment The Rhizoma Pinelliae Radix Scutellariae Rhizoma Coptidis Rhizoma Zingiberis Radix Codonopsis Radix Glycyrrhizae Herba Patriniae Radix Aconiti Lateralis Preparata Radix Angelicae Sinensis The Radix Paeoniae Alba Radix Bupleuri Cortex Magnoliae Officinalis Fructus Jujubae Semen Coicis Rhizoma Atractylodis Semen Arecae sheet Pericarpium Citri Reticulatae
Two 9 9 2 9 6 9 20 60 9 50 6 10 6 30 3 6 6
Three 12 6 5 3 9 6 30 15 12 30 9 3 9 15 9 3 9
Four 10 7 4 5 7 8 25 45 11 40 7 8 7 20 6 4 8
The clinical trial carried out below in conjunction with my institute is described in further detail the present invention:
1. case selection: selected case history is that year August in April, 2013 to 2014 is to our hospital, totally 67 example, man 38 example, female 29 example, age 44-63 year between.
2. diagnostic criteria: " the Chinese medical disease Standardization of diagnosis and curative effect " issued with reference to State Administration of Traditional Chinese Medicine, the initial performance of ulcerative colitis has various ways perhaps, bloody diarrhea is modal early symptom, suffer from abdominal pain in addition, have blood in stool, just pus, just mucus, lose weight, the increase of tenesmus, defecation frequency, colon dysfunction, can not to absorb normally and defecation, there is anemia, the symptom such as to become thin, with complication, as massive hemorrhage, polyp, perforation, ectocolon and pathological changes may, have anxious that break out and chronic point.
3. Therapeutic Method: every day 1 dose point 2 times is oral, and 2 hours after meal oral.15 days is a course for the treatment of, takes and stops 2 days 1 course for the treatment of, then take next course for the treatment of, applies two courses for the treatment of.
4. therapeutic evaluation: according to " the disease of tcm diagnosis standard course for the treatment of ", cure: recover colon function gradually.Take a turn for the better: just pus, have blood in stool and reduce gradually, times of defecation reduces, and form caking stool, pain slowly disappears, and QI and blood is smooth, and inflammation disappears.Do not heal: have blood in stool, pus mucus do not change, tenesmus alleviates, and other clinical symptoms do not change yet.
Therapeutic effect: use the present invention to treat 67 examples, after treat two courses for the treatment of, carry out treatment effectiveness evaluation according to the evaluation criterion course for the treatment of, cure 37 examples, 24 examples that take a turn for the better, 6 more routine, total effective rate is 91%.

Claims (1)

1. treat a Chinese medicine for ulcerative colitis, it is characterized in that: be made up of the crude drug of following weight portion, Rhizoma Pinelliae 9-12, Radix Scutellariae 6-9, Rhizoma Coptidis 2-5, Rhizoma Zingiberis 3-9, Radix Codonopsis 6-9, Radix Glycyrrhizae 6-9, Herba Patriniae 20-30, Radix Aconiti Lateralis Preparata 15-60, Radix Angelicae Sinensis 9-12, Radix Paeoniae Alba 30-50, Radix Bupleuri 6-9, Cortex Magnoliae Officinalis 3-10, Fructus Jujubae 6-9, Semen Coicis 15-30, Rhizoma Atractylodis 3-9, Semen Arecae sheet 3-6, Pericarpium Citri Reticulatae 6-9, adds water above-mentioned raw materials medicine and decocts, filtrate of removing slag to obtain.
CN201510118389.4A 2014-12-11 2015-03-18 Traditional Chinese medicament for treating ulcerative colitis Pending CN104667243A (en)

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CN2014107548021 2014-12-11
CN201510118389.4A CN104667243A (en) 2014-12-11 2015-03-18 Traditional Chinese medicament for treating ulcerative colitis

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105267784A (en) * 2015-11-23 2016-01-27 青岛麦瑞特医药技术有限公司 Traditional Chinese medicine composition for treating ulcerative colitis
CN105343666A (en) * 2015-11-30 2016-02-24 张建英 Traditional Chinese medicine for treating liver and spleen disharmony type ulcerative colitis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012051838A (en) * 2010-09-01 2012-03-15 Taiko Pharmaceutical Co Ltd Anti-inflammatory agent
CN103028098A (en) * 2011-10-09 2013-04-10 刘清友 Preparation method of traditional Chinese medicine prescription for treating ulcerative colitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012051838A (en) * 2010-09-01 2012-03-15 Taiko Pharmaceutical Co Ltd Anti-inflammatory agent
CN103028098A (en) * 2011-10-09 2013-04-10 刘清友 Preparation method of traditional Chinese medicine prescription for treating ulcerative colitis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
岑李民: "中药治疗慢性非特异性溃疡性结肠炎34例观察", 《实用中医药杂志》 *
胡志飞等: "自拟固本清肠汤合百草丹胶囊治疗慢性结肠炎50例", 《实用中医内科杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105267784A (en) * 2015-11-23 2016-01-27 青岛麦瑞特医药技术有限公司 Traditional Chinese medicine composition for treating ulcerative colitis
CN105343666A (en) * 2015-11-30 2016-02-24 张建英 Traditional Chinese medicine for treating liver and spleen disharmony type ulcerative colitis

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Application publication date: 20150603