CN104771657A - Traditional Chinese medicine composition for treating gastric ulcer - Google Patents
Traditional Chinese medicine composition for treating gastric ulcer Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating gastric ulcer. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-40 parts of astragalus membranaceus, 10-30 parts of roasted rhizoma atractylodis macrocephalae, 5-25 parts of dendrobium, 5-25 parts of radix polygonati officinalis, 5-20 parts of fructus evodiae, 5-20 parts of coptis chinensis, 10-40 parts of dandelion, 5-25 parts of scorched rice sprouts, 5-25 parts of coke hawthorn, 5-25 parts of scorched medicated leaven, 5-20 parts of semen raphani, 5-20 parts of pericarpium citri reticulatae viride, 5-20 parts of pericarpium citri reticulatae, 5-25 parts of rhizoma atractylodis, 10-30 parts of cuttlebone, 10-30 parts of rhizoma corydalis, 5-25 parts of fructus toosendan, 5-25 parts of mangnolia officinalis, 5-20 parts of jujube, 5-20 parts of bletilla striata, 5-25 parts of concha arcae, 5-20 parts of costustoot, 5-25 parts of poria cocos and 5-15 parts of ginger processed pinellia. The traditional Chinese medicine composition disclosed by the invention has the efficacies of tonifying the spleen, harmonizing stomach, lowering the adverse flow of qi, alleviating vomiting, helping digestion, removing swelling, and relieving hyperacidity and pain, and is significant in curative effect on the gastric ulcer and reliable in action.
Description
Technical field
The present invention relates to a kind of pharmaceutical product not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of gastric ulcer.
Background technology
Gastric ulcer is a kind of commonly encountered diseases, shows according to Epidemiological study: about have 10% to suffer from primary disease in life at it in population.Gastric ulcer can betide any age, the most common with 45-55 year.The typical performance of gastric ulcer is hungry discomfort, glutted belch, pantothenic acid or chronic middle Upper abdominal pain after the meal, can have melena and hematemesis time serious.Gastric ulcer prolongs silk floss due to the state of an illness, and the state of an illness is complicated, and aggravation or treatment not in time, also can cause the consequences such as hemorrhage, perforation, pyloric obstruction and canceration, serious harm people ' s health.Treatment clinically for gastric ulcer often adopts the therapeutic alliance of 2-3 quasi drugs, and common medicine has: (1) stomach is sticky touches protective agent, as sucralfate; (2) histamine H2 receptor antagonist, if cimetidine, tired Buddhist nun are for fourth, famotidine etc.; (3) antacid, as magnesium hydroxide-aluminium hydroxide adds up to; (4) antibiotics, suppresses helicobacter pylori, as amoxicillin, first pin azoles and bismuth (obtaining promise) etc.; (5) inhibitor, as Aomei azoles (Luo Saike) and blue rope azoles etc.And said medicine can only be taken stopgap measures can not effect a permanent cure for treatment gastric ulcer, bring very large financial burden to patient.
The traditional Chinese medical science is thought, gastric ulcer belongs to " insufficiency of the spleen ", " insufficiency of stomach ", " Deficiency and coldness of spleen and stomach ", " the dirty pain of stomach ", " acid regurgitation ", " vomiting ", the category such as " regurgitation ", by weakness of the spleen and stomach, eating and drinking without temperance, excessive drinking and edible maror, or angry so that impairing the spleen and stomach of being excessively worried, stagnation of stomach-QI and occur epigastric distending pain, the diseases such as dyspepsia, weary acid, belch.
According to theory of Chinese medical science, for the pathogeny of gastric ulcer, adopt the method for the treatment of of invigorating the spleen and regulating the stomach, the de-swelling that helps digestion, relieving gastric hyperacidity to alleviate stomachache, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Adopt drug combination to treat gastric ulcer to there is the deficiency of curing the symptoms, not the disease to overcome in prior art, the invention provides a kind of prepare easy, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of gastric ulcer that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of gastric ulcer, it is characterized in that: its raw material of Chinese medicine and weight are: Radix Astragali 10-40 part, Rhizoma Atractylodis Macrocephalae (parched) 10-30 part, Herba Dendrobii 5-25 part, Rhizoma Polygonati Odorati 5-25 part, Fructus Evodiae 5-20 part, Rhizoma Coptidis 5-20 part, Herba Taraxaci 10-40 part, Fructus Hordei Germinatus (parched to brown) 5-25 part, Fructus Crataegi (parched to brown) 5-25 part, Massa Medicata Fermentata (parched to brown) 5-25 part, Semen Raphani 5-20 part, Pericarpium Citri Reticulatae Viride 5-20 part, Pericarpium Citri Reticulatae 5-20 part, Rhizoma Atractylodis 5-25 part, Endoconcha Sepiae 10-30 part, Rhizoma Corydalis 10-30 part, river Dong 5-25 part, Cortex Magnoliae Officinalis 5-25 part, Fructus Jujubae 5-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-20 part, Concha Arcae 5-25 part, Radix Aucklandiae 5-20 part, Poria 5-25 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of gastric ulcer, it is characterized in that: its raw material of Chinese medicine and weight are: the Radix Astragali 30 parts, Rhizoma Atractylodis Macrocephalae (parched) 20 parts, Herba Dendrobii 15 parts, Rhizoma Polygonati Odorati 15 parts, Fructus Evodiae 10 parts, Rhizoma Coptidis 10 parts, Herba Taraxaci 30 parts, Fructus Hordei Germinatus (parched to brown) 15 parts, Fructus Crataegi (parched to brown) 15 parts, Massa Medicata Fermentata (parched to brown) 15 parts, Semen Raphani 10 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 10 parts, Rhizoma Atractylodis 15 parts, Endoconcha Sepiae 20 parts, Rhizoma Corydalis 20 parts, river Dong 15 parts, Cortex Magnoliae Officinalis 15 parts, 10 parts, Fructus Jujubae, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, Concha Arcae 15 parts, the Radix Aucklandiae 10 parts, 15 parts, Poria, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 parts.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: the Radix Astragali has effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema; Rhizoma Atractylodis Macrocephalae (parched) has effect of dampness row water, QI invigorating, strengthening the spleen and stomach; Herba Dendrobii has effect of reinforcing stomach reg fluid, nourishing YIN and clearing away heat; Rhizoma Polygonati Odorati has effect of nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst; Fructus Evodiae has effect of dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal; Rhizoma Coptidis has effect of heat clearing and damp drying, eliminating fire and detoxication; Herba Taraxaci has heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of inducing diuresis for treating stranguria syndrome; Fructus Hordei Germinatus (parched to brown) has promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back effect of newborn relieving distension; Fructus Crataegi (parched to brown) has effect of promoting digestion and invigorating the stomach, blood circulation promoting and blood stasis dispelling, convergence dysentery relieving; Massa Medicata Fermentata (parched to brown) has invigorating the spleen and regulating the stomach, help digestion the effect in adjusting; Semen Raphani has effect of the de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm; Pericarpium Citri Reticulatae Viride has the stagnant effect of soothing the liver dispelling the stagnated QI, removing food stagnancyization; Pericarpium Citri Reticulatae has effect of diuretic, drying dampness to eliminate phlegm in regulating qi-flowing for strengthening spleen, tune; Rhizoma Atractylodis have effect that is drying damp and strengthening spleen, expelling wind and cold; Endoconcha Sepiae has effect of astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving gastric hyperacidity to alleviate stomachache, removing dampness sore; Rhizoma Corydalis has effect of promoting blood circulation to remove blood stasis, regulating QI to relieve pain; River Dong have soothing the liverly to expel the heat-evil, effect of promoting the circulation of QI to relieve pain, parasite killing; Cortex Magnoliae Officinalis has circulation of qi promoting removing food stagnancy, dampness except effect that is full, lowering the adverse QI to relieve asthma; Fructus Jujubae has effect of invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind; The Pseudobulbus Bletillae (Rhizoma Bletillae) has effect of astringing to arrest bleeding, detumescence and promoting granulation; Concha Arcae has effect of expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache; The Radix Aucklandiae has effect of intestinal stasis relieving in promoting the circulation of QI to relieve pain, tune; Poria has effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) has effect of stopping nausea and vomiting by lowering the adverse flow of QI.The selected medicament composing prescription of the present invention, its drug component, through dialectical compatibility, helps using mutually assistant, plays effect of invigorating the spleen and regulating the stomach, stopping nausea and vomiting by lowering the adverse flow of QI, the de-swelling that helps digestion, relieving gastric hyperacidity to alleviate stomachache altogether, reach treating both the principal and secondary aspects of a disease to the treatment of gastric ulcer.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is reliably evident in efficacy, mild in medicine property and, do not occur toxic and side effects, effective percentage reaches 92.5%, cure rate 66.7%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for gastric ulcer, its raw material of Chinese medicine and weight proportion are: Radix Astragali 30g, Rhizoma Atractylodis Macrocephalae (parched) 20g, Herba Dendrobii 15g, Rhizoma Polygonati Odorati 15g, Fructus Evodiae 10g, Rhizoma Coptidis 10g, Herba Taraxaci 30g, Fructus Hordei Germinatus (parched to brown) 15g, Fructus Crataegi (parched to brown) 15g, Massa Medicata Fermentata (parched to brown) 15g, Semen Raphani 10g, Pericarpium Citri Reticulatae Viride 10g, Pericarpium Citri Reticulatae 10g, Rhizoma Atractylodis 15g, Endoconcha Sepiae 20g, Rhizoma Corydalis 20g, river Dong 15g, Cortex Magnoliae Officinalis 15g, Fructus Jujubae 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g, Concha Arcae 15g, Radix Aucklandiae 10g, Poria 15g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10g.
Embodiment 2
Treat a Chinese medicine composition for gastric ulcer, its raw material of Chinese medicine and weight proportion are: Radix Astragali 15g, Rhizoma Atractylodis Macrocephalae (parched) 30g, Herba Dendrobii 5g, Rhizoma Polygonati Odorati 25g, Fructus Evodiae 12g, Rhizoma Coptidis 20g, Herba Taraxaci 15g, Fructus Hordei Germinatus (parched to brown) 25g, Fructus Crataegi (parched to brown) 10g, Massa Medicata Fermentata (parched to brown) 20g, Semen Raphani 5g, Pericarpium Citri Reticulatae Viride 15g, Pericarpium Citri Reticulatae 12g, Rhizoma Atractylodis 25g, Endoconcha Sepiae 15g, Rhizoma Corydalis 30g, river Dong 10g, Cortex Magnoliae Officinalis 20g, Fructus Jujubae 5g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Concha Arcae 10g, Radix Aucklandiae 20g, Poria 5g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 12g.
Embodiment 3
Treat a Chinese medicine composition for gastric ulcer, its raw material of Chinese medicine and weight proportion are: Radix Astragali 25g, Rhizoma Atractylodis Macrocephalae (parched) 15g, Herba Dendrobii 20g, Rhizoma Polygonati Odorati 10g, Fructus Evodiae 15g, Rhizoma Coptidis 5g, Herba Taraxaci 25g, Fructus Hordei Germinatus (parched to brown) 10g, Fructus Crataegi (parched to brown) 20g, Massa Medicata Fermentata (parched to brown) 5g, Semen Raphani 20g, Pericarpium Citri Reticulatae Viride 12g, Pericarpium Citri Reticulatae 15g, Rhizoma Atractylodis 10g, Endoconcha Sepiae 30g, Rhizoma Corydalis 15g, river Dong 25g, Cortex Magnoliae Officinalis 10g, Fructus Jujubae 20g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Concha Arcae 25g, Radix Aucklandiae 12g, Poria 20g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5g.
Embodiment 4
Treat a Chinese medicine composition for gastric ulcer, its raw material of Chinese medicine and weight proportion are: Radix Astragali 10g, Rhizoma Atractylodis Macrocephalae (parched) 25g, Herba Dendrobii 10g, Rhizoma Polygonati Odorati 20g, Fructus Evodiae 5g, Rhizoma Coptidis 15g, Herba Taraxaci 10g, Fructus Hordei Germinatus (parched to brown) 20g, Fructus Crataegi (parched to brown) 5g, Massa Medicata Fermentata (parched to brown) 25g, Semen Raphani 12g, Pericarpium Citri Reticulatae Viride 20g, Pericarpium Citri Reticulatae 5g, Rhizoma Atractylodis 20g, Endoconcha Sepiae 10g, Rhizoma Corydalis 25g, river Dong 5g, Cortex Magnoliae Officinalis 25g, Fructus Jujubae 12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Concha Arcae 5g, Radix Aucklandiae 15g, Poria 10g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15g.
Embodiment 5
Treat a Chinese medicine composition for gastric ulcer, its raw material of Chinese medicine and weight proportion are: Radix Astragali 40g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Herba Dendrobii 25g, Rhizoma Polygonati Odorati 5g, Fructus Evodiae 20g, Rhizoma Coptidis 12g, Herba Taraxaci 40g, Fructus Hordei Germinatus (parched to brown) 5g, Fructus Crataegi (parched to brown) 25g, Massa Medicata Fermentata (parched to brown) 10g, Semen Raphani 15g, Pericarpium Citri Reticulatae Viride 5g, Pericarpium Citri Reticulatae 20g, Rhizoma Atractylodis 10g, Endoconcha Sepiae 25g, Rhizoma Corydalis 10g, river Dong 20g, Cortex Magnoliae Officinalis 5g, Fructus Jujubae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 12g, Concha Arcae 20g, Radix Aucklandiae 5g, Poria 25g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 8g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 6 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 4 centimetres, decocts 15 ~ 20 minutes after water boils.Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition for the treatment of gastric ulcer given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 120 example, man 69 example, female 51 example, 30 ~ 65 years old age.
Two, diagnosis basis:
1, periodical attack, normal relevant with seasonal variations, Nervous and Mental Factors, drinking and eating irregularly or long-term taking antibiotic medicine;
2, under xiphoid-process (pit of the stomach) or epigastrium in burning property, nibbling property or inanition pain or night pain, pain can because taking food, drinking water, take antacid and alleviate;
3 or with heartburn, the symptom such as acid regurgitation water, belch, anemia, black or pitch sample stool;
4, the visible ulcer of Χ ray examination " niche ", fecal occult blood testing is positive;
5, other check, as gastroscope, gastric acidity determination etc.
Three, usage and dosage: during clinical practice, potion on the one, decocting twice extracting juice is about 400ml, point morning, late twice empty stomach decoction being taken warmly.It within six days, is a course for the treatment of.Treatments period is avoided cold and uncooked food the thing of pungent stimulation.
Four, criterion of therapeutical effect:
1, cure: clinical manifestation disappears all completely, ulcer disappearance or cicatrization and without congestion and edema under mirror;
2, effective: clinical manifestation obviously improves, ulcer surface reduce more than 50% or ulcer surface totally, only there is a small amount of tongue film;
3, invalid: clinical manifestation without alleviation, ulcer surface is unchanged or increase the weight of.
Five, therapeutic effect: in this clinical observation case, takes medicine 2-8 the course for the treatment of, and recovery from illness 80 example, follows up a case by regular visits to and have no recurrence; Effective 31 examples, no effect 9.There is not toxic and side effects in treatments period.
Six, model case:
Case 1: blue certain, female, 43 years old.Private prosecution time medical: upper abdomen gastral cavilty portion is uncomfortable, pain half a year, and with diseases such as heartburn, acid regurgitation water, belch, once took western medicine, unsatisfactory curative effect.Gastroscopy is pointed out: gastric ulcer.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, uncomfortable, pain obviously alleviates, and heartburn disease such as grade disappears; Continue to take 2 courses for the treatment of, clinical symptoms disappears completely, and gastroscopy ulcer disappears, and cures.
Case 2: Wang, man, 52 years old.Private prosecution time medical: distending pain under xiphoid-process, after meal feeling of repletion, occasionally has belch, returns acid.Gastroscopy is pointed out: gastric ulcer.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, remission; Continue to take 3 courses for the treatment of, symptom disappears completely.Follow up a case by regular visits to so far without recurrence.
Claims (2)
1. treat the Chinese medicine composition of gastric ulcer for one kind, it is characterized in that: its raw material of Chinese medicine and weight are: Radix Astragali 10-40 part, Rhizoma Atractylodis Macrocephalae (parched) 10-30 part, Herba Dendrobii 5-25 part, Rhizoma Polygonati Odorati 5-25 part, Fructus Evodiae 5-20 part, Rhizoma Coptidis 5-20 part, Herba Taraxaci 10-40 part, Fructus Hordei Germinatus (parched to brown) 5-25 part, Fructus Crataegi (parched to brown) 5-25 part, Massa Medicata Fermentata (parched to brown) 5-25 part, Semen Raphani 5-20 part, Pericarpium Citri Reticulatae Viride 5-20 part, Pericarpium Citri Reticulatae 5-20 part, Rhizoma Atractylodis 5-25 part, Endoconcha Sepiae 10-30 part, Rhizoma Corydalis 10-30 part, river Dong 5-25 part, Cortex Magnoliae Officinalis 5-25 part, Fructus Jujubae 5-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-20 part, Concha Arcae 5-25 part, Radix Aucklandiae 5-20 part, Poria 5-25 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5-15 part.
2. a kind of Chinese medicine composition for the treatment of gastric ulcer according to claim 1, is characterized in that: its raw material of Chinese medicine and weight are: the Radix Astragali 30 parts, Rhizoma Atractylodis Macrocephalae (parched) 20 parts, Herba Dendrobii 15 parts, Rhizoma Polygonati Odorati 15 parts, Fructus Evodiae 10 parts, Rhizoma Coptidis 10 parts, Herba Taraxaci 30 parts, Fructus Hordei Germinatus (parched to brown) 15 parts, Fructus Crataegi (parched to brown) 15 parts, Massa Medicata Fermentata (parched to brown) 15 parts, Semen Raphani 10 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 10 parts, Rhizoma Atractylodis 15 parts, Endoconcha Sepiae 20 parts, Rhizoma Corydalis 20 parts, river Dong 15 parts, Cortex Magnoliae Officinalis 15 parts, 10 parts, Fructus Jujubae, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, Concha Arcae 15 parts, the Radix Aucklandiae 10 parts, 15 parts, Poria, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 parts.
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