CN104771585A - Traditional Chinese medicine composition for treating acute nephritis and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating acute nephritis and preparation method thereof Download PDF

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CN104771585A
CN104771585A CN201510198634.7A CN201510198634A CN104771585A CN 104771585 A CN104771585 A CN 104771585A CN 201510198634 A CN201510198634 A CN 201510198634A CN 104771585 A CN104771585 A CN 104771585A
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王立昌
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王立昌
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Abstract

The invention discloses a traditional Chinese medicine composition for treating acute nephritis. The composition is mainly prepared from the following medicinal raw materials in parts by mass: 12-17 parts of radix paeoniae alba, 5-9 parts of lawn pennywort herb, 8-12 parts of frog orchid tuber, 7-13 parts of caulis clematidis armandii, 8-15 parts of kudzu vine root, 9-12 parts of bidens bipinnata, 10-13 parts of ligusticum wallichii, 9-15 parts of girald pteroxygonum root, 11-13 parts of pinkflush rhododendron root, 6-14 parts of rhizoma cimicifugae, 13-18 parts of black nightshade, 10-12 parts of Japanese cayratia herb, 12-17 parts of Chinese yam and 11-16 parts of obcordate christia herb. Years of clinical practice proves that the traditional Chinese medicine composition has the effects of clearing heat, inducing diuresis, removing toxicity, diminishing swelling, tonifying kidneys and strengthening waist, has a remarkable curative effect, and can be used for treating both symptoms and root causes.

Description

A kind of Chinese medicine composition and preparation method for the treatment of acute nephritis
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine composition and preparation method for the treatment of acute nephritis.
Background technology
Acute nephritis (that is: acute glomerulonephritis) is a kind of both sides kidney diffusivity glomerular epithelial cell caused owing to infecting rear allergy is main acute illness.Its feature is Acute onset, and hematuria, albuminuria, edema and hypertension can accompany transient azotemia, has spontaneous recovery tendency.After being common in streptococcal infection, and other antibacterials, virus and parasitic infection also can cause.Acute nephritis is more common in child, male.Usually 1 ~ 3 week onset after forerunner infects, induce the time of body generation needed for immune complex after being equivalent to pathogenic antigens initial immunity incubation period, the incubation period of respiratory tract infection person is short compared with skin infection person.Primary disease onset is comparatively anxious, and state of an illness weight differs, and the lighter is Subclinical (only having routine urinalysis extremely); Typical case person is performance in acute nephritic syndrome, and comprise hematuria, haemproteins, edema, hypertension or renal dysfunction etc., serious symptom person acute renal failure can occur.
Publication No. 104383329A(application number 201410655585.0) Chinese patent literature disclose a kind of Chinese medicine preparation being used for the treatment of acute nephritis, the raw material of Chinese medicine of selection and weight portion respectively: the Radix Astragali 30 parts, Rhizoma Dioscoreae 30 parts, Herba Plantaginis 15 parts, Folium Pyrrosiae 18 parts, Herba Emiliae 15 parts, Cortex Moutan 10 parts, Radix Rehmanniae Preparata 24 parts, Rhizoma Imperatae 15 parts, Rhizoma Alismatis 15 parts, Radix Bupleuri 7 parts.Publication No. CN 103479915 A(application number 201310425441.1) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of acute nephritis and preparation method thereof.This Chinese medicine composition is prepared from by the raw material comprising following weight portion: Herba Ephedrae, Fructus Forsythiae, Semen Phaseoli, Flos Lonicerae, Herba Taraxaci, Herba Violae, Rhizoma Imperatae, rubia, Herba Agrimoniae.Publication No. CN 104042950 A(application number 201410266598.9) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of acute nephritis and preparation method thereof, chemotherapeutic agent for current acute nephritis is larger to liver toxicity, the present situation of unsatisfactory curative effect, the Chinese medicine composition providing a kind for the treatment of or prevention acute nephritis of the present invention, it comprises following component: Fructus Forsythiae, Ramulus Cinnamomi, Periostracum Cicadae, Herba Houttuyniae, Radix Achyranthis Bidentatae, Bulbus Lilii, Herba Leonuri, Rhizoma Alismatis, Pericarpium Citri Reticulatae, Pericarpium Arecae, Herba Ephedrae, Cortex Sclerotii Poriae, Rhizoma Imperatae, Radix Isatidis, Cortex Mori, Radix Glycyrrhizae.
Western medicine acute nephritis mostly is antibiotic, infringement health, and side effect is large, and Chinese traditional treatment safety is high, focuses on the Repair and protection of kidney, has effect for the treatment of both the principal and secondary aspects of a disease, therefore need to work out formula more how evident in efficacy.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take Chinese medicine composition and the preparation method of the wide treatment acute nephritis of safe and applicable.
Technical scheme of the present invention is:
Treat a Chinese medicine composition for acute nephritis, be prepared from primarily of following bulk drugs, be mass parts: Radix Paeoniae Alba 12-17; Herba Hydrocotyles 5-9; Radix Habenariae Delavayi 8-12; Caulis Clematidis Armandii 7-13; Radix Puerariae 8-15; Herba Bidentis Bipinnatae 9-12; Rhizoma Chuanxiong 10-13; Radix Polygoni Ciliinerve 9-15; Radix Rhododendri 11-13; Rhizoma Cimicifugae 6-14; Herba Solani Nigri 13-18; Herba Cayatiae Japonicae 10-12; Rhizoma Dioscoreae 12-17; Herba Christiae Obcordatae 11-16.
Preferred version is, Radix Paeoniae Alba 13-16; Herba Hydrocotyles 6-8; Radix Habenariae Delavayi 9-11; Caulis Clematidis Armandii 9-11; Radix Puerariae 10-13; Herba Bidentis Bipinnatae 10-11; Rhizoma Chuanxiong 11-12; Radix Polygoni Ciliinerve 10-14; Radix Rhododendri 11.5-12.5; Rhizoma Cimicifugae 8-12; Herba Solani Nigri 14-17; Herba Cayatiae Japonicae 10.5-11.5; Rhizoma Dioscoreae 13-16; Herba Christiae Obcordatae 12-15.
More preferably, the Radix Paeoniae Alba 14.5; Herba Hydrocotyles 7; Radix Habenariae Delavayi 10; Caulis Clematidis Armandii 10; Radix Puerariae 11.5; Herba Bidentis Bipinnatae 10.5; Rhizoma Chuanxiong 11.5; Radix Polygoni Ciliinerve 12; Radix Rhododendri 12; Rhizoma Cimicifugae 10; Herba Solani Nigri 15.5; Herba Cayatiae Japonicae 11; Rhizoma Dioscoreae 14.5; Herba Christiae Obcordatae 13.5.
Described a kind of Chinese medicine composition for the treatment of acute nephritis, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, decoct with water, big fire is heated to boiling, continue 10 minutes, then add step (1) made crude drug, turn little fire and decoct 15-25 minute (preferably: turn little fire and decoct 17-23 minute; Be more preferably: turn little fire and decoct 20 minutes), filter, collect filtrate;
(5) made to step (2) (3) crude drug is pulverized, add in step (4) made filtrate, stir, obtain decoction.
Described a kind of preparation method for the treatment of the Chinese medicine composition decoction of acute nephritis, the 5-8 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 6-7 that amount of water is boiled crude drug quality is doubly; Be more preferably: amount of water is 6.5 times of boiled crude drug quality).
Described a kind of Chinese medicine composition for the treatment of acute nephritis, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) to decoct, big fire is heated to boiling, continues 10 minutes, turn little fire to decoct, filter, collect filtrate, heating concentrated filtrate is to thick paste;
(5) pulverized by made to step (1) (2) (3) crude drug, mix, add adjuvant, pill block, pill bar with step (4) gained thick paste, segmentation granulating, dry packing, obtains pill.
Described a kind of preparation method for the treatment of the Chinese medicine composition pill of acute nephritis, step (4) turns little fire and decocts 15-25 minute (preferably: turn little fire and decoct 17-23 minute; Be more preferably: turn little fire and decoct 20 minutes).
Described a kind of Chinese medicine composition for the treatment of acute nephritis, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) to decoct, big fire is heated to boiling, continues 10 minutes, turn little fire to decoct 20 minutes, filter, collect filtrate, this filtrate of spraying dry;
(5) by step (1) (2) (3) (4) made crude drug and dry thing, pulverize and sieve, obtain powder.
Described a kind of preparation method for the treatment of the Chinese medicine composition composition powders of acute nephritis, it is (preferred: to pulverize 160-200 mesh sieve that step (5) pulverized 140-220 mesh sieve; Be more preferably: pulverized 180 mesh sieves).
Described a kind of Chinese medicine composition for the treatment of acute nephritis, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) to decoct, big fire is heated to boiling, continues 10 minutes, turn little fire to decoct 20 minutes, filter, collect filtrate, this filtrate of spraying dry;
(5) by step (1) (2) (3) (4) made crude drug and dry thing, pulverized 140 mesh sieves, obtained medicated powder, then added adjuvant cane sugar powder, and be packed in capsule according to the metering of 0.45g/ grain, obtain capsule.
Described a kind of preparation method for the treatment of the Chinese medicinal composition capsules agent of acute nephritis, the amount of step (5) adjuvant cane sugar powder is the 0.2-0.4 of medicated powder quality doubly (preferred: the amount of adjuvant cane sugar powder is 0.3 times of medicated powder quality).
A kind of Traditional Chinese medicine composition formula science for the treatment of acute nephritis provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, evident in efficacy, and cure rate is high, effectively can reduce relapse rate;
2, products obtained therefrom of the present invention has effect of clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, replenishing kidney, strengthening waist;
3, Chinese crude drug selected by the present invention, safety has no side effect, can long-term taking, tonification health.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
The Radix Paeoniae Alba: base is former: be the root of ranunculaceae plant Radix Paeoniae (cultigen).Nature and flavor with return through, bitter, sour, be slightly cold.Return liver, spleen channel.There is nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, stabilize effect of sun.For blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, has a headache dizzy.
Herba Hydrocotyles: base is former: be the herb of samphire Herba Hydrocotyles and Hydrocotyle sibthorpioides lam.Var.Batvachium (Hand.-Mazz.) et shan..Chemical analysis: herb is containing flavones ingredient: Quercetin, Quercetin-3-galactoside, isorhamnetin, Quercetin-3-O-β-D-(6-caffeoyl galactoside).Again containing wooden body composition, left-handed sesamin and Mus Body components: stigmasterol.Not containing coumarin.Nature and flavor: acrid in the mouth; Micro-hardship; Cool in nature.Function cures mainly: clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.Main jaundice; Dysentery; Edema; Stranguria; Corneal nebula; Larynx swells; Carbuncle sore tumefacting virus; Herpes zoster; Traumatic injury.
Radix Habenariae Delavayi: base is former: be the tuber of the beautiful phoenix flower of the thick lobe of orchid.Nature and flavor: sweet; Micro-pungent; Temperature.Gui Jing: kidney channel.Function cures mainly: replenishing kidney, strengthening waist; Regulating QI to relieve pain.Main lumbago due to renal deficiency; Hernia; The stagnation of QI is had a stomachache.
Caulis Clematidis Armandii: base is former: be the dry rattan of ranunculaceae plant Herba Clematidis Lasiandrae or Clematis montana.Nature and flavor with return through: bitter, cold.GUIXIN, small intestinal, urinary bladder channel.Function with cure mainly: inducing diuresis for treating stranguria syndrome, clear away heart-fire relieving restlessness, stimulating milk secretion of stimulating the menstrual flow.For stranguria, edema, vexed dark coloured urine, aphtha of the mouth and tongue, amenorrhea breast is few, damp and hot arthralgia pain.
Radix Puerariae: nature and flavor: sweet, pungent, cool.Gui Jing: return spleen, stomach warp.Effect: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Cure mainly: for fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Herba Bidentis Bipinnatae: base is former: be the herb of feverfew Herba Bidentis Bipinnatae.Chemical analysis: herb is containing alkaloid, tannin, Saponin, flavonoid glycoside.Stem and leaf is containing volatile oil, tannin, amaroid, choline etc.Fruit oil-containing 27.3%.Nature and flavor: bitter in the mouth; Cold nature.Function cures mainly: heat-clearing and toxic substances removing; Expelling wind and removing dampness; Promoting blood circulation and detumescence.Main throat; Swell and ache; Have loose bowels; Dysentery; Jaundice; Intestinal carbuncle; Furuncle swelling toxin; Serpentis is early bitten; Rheumatic arthralgia; Traumatic injury.
Rhizoma Chuanxiong: nature and flavor with return through: pungent, temperature.Return liver, gallbladder, pericardium channel.Function cures mainly: activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Radix Polygoni Ciliinerve: base is former: be the tuber of polygonaceae plant floating and thready pulse knotweed.Nature and flavor: bitter in the mouth is micro-puckery, cool in nature.Gui Jing: lung; Large intestine; Liver Channel.Function cures mainly: raw use: anti-inflammation, pleasantly invigorates blood circulation, cooling blood for hemostasis, tranquillizing to relieve muscle spasm, pain relieving, and antidiarrheal, promotes ulcer healing; Salt person the kidney invigorating, vinegar person stops blooding, alkali person stomach invigorating.Treating tonsillitis, enteritis, gastritis, Peptic Ulcers, bacillary dysentery, ascariasis of biliary tract, trauma infection contamination, cellulitis, carbuncle furuncle, purulent, urinary system infection, menoxenia, metrorrhagia, traumatic hemorrhage, spit blood, epistaxis, has blood in stool, traumatic injury, lumbago, skelalgia of rheumatism.
Radix Rhododendri: base is former: be root and the leaf of the bright hair Cuculus polioephalus of ericad.Nature and flavor: bitter; Cool in nature.Gui Jing: the heart; Urinary bladder channel.Function cures mainly: heat clearing away; Diuresis.Main infantile convulsion; Acute and chronic nephritis; Pyelonephritis.
Rhizoma Cimicifugae: base is former: be the root stock of ranunculaceae plant Rhizoma Cimicifugae, Cimicifuga Dahurica and C.heracleifolia.Nature and flavor with return through: pungent, micro-sweet, be slightly cold.Return lung, spleen, stomach, large intestine channel.Function with cure mainly: deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome sends out speckle, uterine prolapse.
Herba Solani Nigri: base is former: be the herb of plant of Solanaceae Herba Solani Nigri.Chemical analysis: determine alkali, Saponin, vitamin C, resin containing solanine, Australia's solanamine, Herba Solani Nigri.Nature and flavor: bitter, cold.Function cures mainly: heat-clearing and toxic substances removing; Promoting blood circulation and detumescence.Main furuncle; Carbuncle; Erysipelas; Osteopatia sprain; Chronic tracheitis; Oedema due to nephritis.
Herba Cayatiae Japonicae: base is former: be herb or the root of vitaceae Herba Cayatiae Japonicae.Nature and flavor: bitter; Acid; Cold.Gui Jing: the heart; Liver; Stomach warp.Function cures mainly: clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.Main pyretic toxicity carbuncle; Furuncle; Erysipelas; Laryngopharynx swelling and pain; Snake bite and insect sting; Burn due to hot liquid or fire; Rheumatic arthralgia; Jaundice; Dysentery; Nebulousurine; Hematuria.
Rhizoma Dioscoreae: nature and flavor: sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, effect of the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Herba Christiae Obcordatae: base is former: be the Herb of leguminous plant floor file Vespertilio grass.Nature and flavor: toil; Cold; Nontoxic.Gui Jing: lung; The heart; Kidney; Urinary bladder channel.Function cures mainly: relieving stranguria by diuresis, and dissipating blood stasis stops blooding, heat-clearing and toxic substances removing.Main dysuria, stranguria caused by urinary stone, edema, leucorrhea, traumatic injury, spits blood, spitting of blood, metrorrhagia, conjunctival congestion with ophthalmalgia, acute mastitis, venom.
embodiment 1treat a Chinese medicine composition for acute nephritis, be prepared from (every part of 10g) primarily of following bulk drugs: the Radix Paeoniae Alba 12 parts, Herba Hydrocotyles 5 parts, Radix Habenariae Delavayi 8 parts, Caulis Clematidis Armandii 7 parts, Radix Puerariae 8 parts, Herba Bidentis Bipinnatae 9 parts, Rhizoma Chuanxiong 10 parts, Radix Polygoni Ciliinerve 9 parts, Radix Rhododendri 11 parts, Rhizoma Cimicifugae 6 parts, Herba Solani Nigri 13 parts, Herba Cayatiae Japonicae 10 parts, Rhizoma Dioscoreae 12 parts, Herba Christiae Obcordatae 11 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine composition decoction of acute nephritis is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 12 minutes, transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 25 minutes, take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, add the soak by water of boiled crude drug quality 6.5 times, big fire is heated to boiling, continues 10 minutes, add step (1) made crude drug again, turn little fire to decoct 20 minutes, filter, collect filtrate;
(5) made to step (2) (3) crude drug is pulverized, add in step (4) made filtrate, stir, obtain decoction.
embodiment 2treat a Chinese medicine composition for acute nephritis, be prepared from (every part of 10g) primarily of following bulk drugs: the Radix Paeoniae Alba 17 parts, Herba Hydrocotyles 9 parts, Radix Habenariae Delavayi 12 parts, Caulis Clematidis Armandii 13 parts, Radix Puerariae 15 parts, Herba Bidentis Bipinnatae 12 parts, Rhizoma Chuanxiong 13 parts, Radix Polygoni Ciliinerve 15 parts, Radix Rhododendri 13 parts, Rhizoma Cimicifugae 14 parts, Herba Solani Nigri 18 parts, Herba Cayatiae Japonicae 12 parts, Rhizoma Dioscoreae 17 parts, Herba Christiae Obcordatae 16 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine composition pill of acute nephritis is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 12 minutes, transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 25 minutes, take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, add the soak by water of boiled crude drug quality 6 times, big fire is heated to boiling, continues 10 minutes, turns little fire and decocts 20 minutes, filter, collect filtrate, heating concentrated filtrate is to thick paste;
(5) pulverized by made to step (1) (2) (3) crude drug, mix, add adjuvant, pill block, pill bar with step (4) gained thick paste, segmentation granulating, dry packing, obtains pill.
Model case: xxx, male, 6 years old.Patient because of hematuria, edema three days, with grade fever, feel sick medical, blood pressure 152/93mmHg on inspection, routine urinalysis shows, urine protein (++), gross hematuria, is diagnosed as acute nephritis, after taking antibiotic therapy, patient has anaphylaxis, then seeks Chinese traditional treatment.
Take this example gained pill, each 3-4 grain, warm boiled water, one day twice, within 20 days, be a course for the treatment of, patient takes three days, Nausea and vomiting transference cure, urine volume increases, and after taking a course for the treatment of, hematuria, edema are obviously alleviated, after taking again a course for the treatment of, further consultation checks, indices is all normal, and patient fully recovers.
embodiment 3treat a Chinese medicine composition for acute nephritis, be prepared from (every part of 10g) primarily of following bulk drugs: the Radix Paeoniae Alba 13 parts, Herba Hydrocotyles 6 parts, Radix Habenariae Delavayi 9 parts, Caulis Clematidis Armandii 9 parts, Radix Puerariae 10 parts, Herba Bidentis Bipinnatae 10 parts, Rhizoma Chuanxiong 11 parts, Radix Polygoni Ciliinerve 10 parts, Radix Rhododendri 11.5 parts, Rhizoma Cimicifugae 8 parts, Herba Solani Nigri 14 parts, Herba Cayatiae Japonicae 10.5 parts, Rhizoma Dioscoreae 13 parts, Herba Christiae Obcordatae 12 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine composition composition powders of acute nephritis is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 12 minutes, transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 25 minutes, take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, add the soak by water of boiled crude drug quality 6 times, big fire is heated to boiling, continues 10 minutes, turns little fire and decocts 20 minutes, filter, collect filtrate, this filtrate of spraying dry;
(5) by step (1) (2) (3) (4) made crude drug and dry thing, pulverized 180 mesh sieves, obtained powder.
Model case: xxx, women, 52 years old.Main suit: patient is weak and sickly, first quarter moon cause is suffered from cold and catches a cold, and infusion treatment is after one week, sb.'s illness took a favorable turn, realize face's edema within the next few days, hypourocrinia, urine muddy stain, and body void is weak, lumbago anorexia, on inspection, urine examination is positive, urine protein +++, occult blood ++, be diagnosed as acute glomerulonephritis.
Recommend to take this example gained powder, each 3-4g, warm boiled water through people, one day twice 20 days is a course for the treatment of, after patient takes a course for the treatment of, edema disappears, the uncomfortable diseases such as body void is weak, lumbago obviously alleviate, and continue to take a course for the treatment of, uncomfortable disease all disappears, the mental status improves, further consultation routine urinalysis is negative, and in drug withdrawal 1 year, the state of an illness does not recur.
embodiment 4treat a Chinese medicine composition for acute nephritis, be prepared from (every part of 10g) primarily of following bulk drugs: the Radix Paeoniae Alba 16 parts, Herba Hydrocotyles 8 parts, Radix Habenariae Delavayi 11 parts, Caulis Clematidis Armandii 11 parts, Radix Puerariae 13 parts, Herba Bidentis Bipinnatae 11 parts, Rhizoma Chuanxiong 12 parts, Radix Polygoni Ciliinerve 14 parts, Radix Rhododendri 12.5 parts, Rhizoma Cimicifugae 12 parts, Herba Solani Nigri 17 parts, Herba Cayatiae Japonicae 11.5 parts, Rhizoma Dioscoreae 16 parts, Herba Christiae Obcordatae 15 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicinal composition capsules agent of acute nephritis is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 12 minutes, transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 25 minutes, take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, add the soak by water of boiled crude drug quality 6 times, big fire is heated to boiling, continues 10 minutes, turns little fire and decocts 20 minutes, filter, collect filtrate, this filtrate of spraying dry;
(5) by step (1) (2) (3) (4) made crude drug and dry thing, pulverized 140 mesh sieves, obtained medicated powder, then added the adjuvant cane sugar powder of medicated powder quality 0.3 times, and be packed in capsule according to the metering of 0.45g/ grain, obtain capsule.
Model case: xxx, male, 17 years old.Main suit: eyelid and edema of lower limbs three days, oliguria, lumbago five days; Medical history: patient is before five days, and be not intended to find that there is oliguria, lumbago symptom, do not take notice of, the rear state of an illness increases the weight of gradually, eyelid and lower limb start edema, short red with inappetence, yellowish urine, go to see a doctor, and routine urinalysis shows, urine protein +++, erythrocyte ++, be diagnosed as acute glomerulonephritis.
Take this example gained capsule, each 3-4 grain, warm boiled water, one day twice, within 20 days, be a course for the treatment of, after patient takes five days, urine volume obviously increases, and edema disappears gradually, adhere to taking a course for the treatment of, uncomfortable disease is all eliminated, and urine routine test is normal, and patient fully recovers.
embodiment 5treat a Chinese medicine composition for acute nephritis, be prepared from (every part of 10g) primarily of following bulk drugs: the Radix Paeoniae Alba 14.5 parts, Herba Hydrocotyles 7 parts, Radix Habenariae Delavayi 10 parts, Caulis Clematidis Armandii 10 parts, Radix Puerariae 11.5 parts, Herba Bidentis Bipinnatae 10.5 parts, Rhizoma Chuanxiong 11.5 parts, Radix Polygoni Ciliinerve 12 parts, Radix Rhododendri 12 parts, Rhizoma Cimicifugae 10 parts, Herba Solani Nigri 15.5 parts, Herba Cayatiae Japonicae 11 parts, Rhizoma Dioscoreae 14.5 parts, Herba Christiae Obcordatae 13.5 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine composition decoction of acute nephritis is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 12 minutes, transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 25 minutes, take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, add the soak by water of boiled crude drug quality 6.5 times, big fire is heated to boiling, continues 10 minutes, add step (1) made crude drug again, turn little fire to decoct 20 minutes, filter, collect filtrate;
(5) made to step (2) (3) crude drug is pulverized, add in step (4) made filtrate, stir, obtain decoction.
test example 1a kind of clinical practice for the treatment of the Chinese medicine composition (embodiment 5) of acute nephritis of gained of the present invention:
Choose crowd: in June, 2013 in December ,-2014, according to medical case history, patient 360 example of acute nephritis is diagnosed as four hospital's screenings, wherein male patient 237 example, female patient 123 example, the age is minimum is 6 years old, be 68 years old to the maximum, 26.3 ± 1.2 years old mean age, with 8-18 year maximum, the course of disease 3 days-4 months.Diagnosis basis: 1. morbidity is anxious, and state of an illness weight differs, and the lighter can without clinical symptoms, most of prognosis bona, and the course of disease is generally within 1 year; 2. have albuminuria, hematuria (under mirror or gross hematuria), cylinderuria, often have edema, hypertension or of short duration azotemia, ultrasound diagnosis kidney is without reducing; 3. some cases has acute meningitis from Streptococcus pneumoniae history, 1-3 week morbidity after infection.
Before test, patient is divided into two groups at random, experimental group 244 example and matched group 116 routine, two groups in age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, one day twice, each 120-160ml, warmly takes, and within 20 days, is a course for the treatment of; Matched group takes other conventional medicines (shenyankangfu tablet, SHENFUKANG JIAONANG, SHILINTONG PIAN etc.).Period in a medicine carries out Continuous Observation to two groups of patients, and record symptom and change, followed up a case by regular visits to after 1 year, record recurrence number of cases.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: the Sxs such as edema, oliguria, hematuria, hypertension disappear, and urine examination is negative; (2) effective: the Sxs such as edema, oliguria, hematuria, hypertension disappear or major part disappears, urine protein one (+) below, erythrocyte L EssT.LTssT.LT 15/high power lens, erythrocyte cuts down more than one (+); (3) invalid: symptom and sign are not obviously improved, and urine examination is positive.
Clinical effectiveness: after the taking medicine of two courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, the healing patient of experimental group is 151 examples, cure rate is 61.9%, effective patient is 86 examples, effective percentage is 35.2%, and total effective rate is 97.1%, and the patient that matched group is cured is 53 examples, cure rate is 45.7%, effective patient is 40 examples, and effective percentage is 34.5%, total effective rate 80.2%, significantly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high, and by comparing the relapse rate of two groups of patients, products obtained therefrom of the present invention can be known, effectively avoid the state of an illness again to recur.
The Chinese medicine used in the present invention, multiple medical material synergism, the Radix Paeoniae Alba of nourishing blood for regulating menstruation, the Herba Hydrocotyles of clearing away heat-damp and promoting diuresis, Radix Rhododendri and Herba Cayatiae Japonicae, the Radix Habenariae Delavayi of replenishing kidney, strengthening waist, the Caulis Clematidis Armandii of inducing diuresis for treating stranguria syndrome and Herba Christiae Obcordatae, the Radix Puerariae of expelling pathogenic factors from muscles for reducing heat, the Herba Bidentis Bipinnatae of heat-clearing and toxic substances removing, Rhizoma Cimicifugae and Herba Solani Nigri, the Rhizoma Chuanxiong of dispeiling pathogenic wind and removing dampness, the Radix Polygoni Ciliinerve of anti-inflammation, the Rhizoma Dioscoreae of the kidney invigorating arresting seminal emission, play effect of clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, replenishing kidney, strengthening waist altogether, effectively eliminate uncomfortable disease, heighten the effect of a treatment.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat a Chinese medicine composition for acute nephritis, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Radix Paeoniae Alba 12-17; Herba Hydrocotyles 5-9; Radix Habenariae Delavayi 8-12; Caulis Clematidis Armandii 7-13; Radix Puerariae 8-15; Herba Bidentis Bipinnatae 9-12; Rhizoma Chuanxiong 10-13; Radix Polygoni Ciliinerve 9-15; Radix Rhododendri 11-13; Rhizoma Cimicifugae 6-14; Herba Solani Nigri 13-18; Herba Cayatiae Japonicae 10-12; Rhizoma Dioscoreae 12-17; Herba Christiae Obcordatae 11-16.
2. a kind of Chinese medicine composition for the treatment of acute nephritis as claimed in claim 1, is characterized in that, Radix Paeoniae Alba 13-16; Herba Hydrocotyles 6-8; Radix Habenariae Delavayi 9-11; Caulis Clematidis Armandii 9-11; Radix Puerariae 10-13; Herba Bidentis Bipinnatae 10-11; Rhizoma Chuanxiong 11-12; Radix Polygoni Ciliinerve 10-14; Radix Rhododendri 11.5-12.5; Rhizoma Cimicifugae 8-12; Herba Solani Nigri 14-17; Herba Cayatiae Japonicae 10.5-11.5; Rhizoma Dioscoreae 13-16; Herba Christiae Obcordatae 12-15(is preferably: the Radix Paeoniae Alba 14.5; Herba Hydrocotyles 7; Radix Habenariae Delavayi 10; Caulis Clematidis Armandii 10; Radix Puerariae 11.5; Herba Bidentis Bipinnatae 10.5; Rhizoma Chuanxiong 11.5; Radix Polygoni Ciliinerve 12; Radix Rhododendri 12; Rhizoma Cimicifugae 10; Herba Solani Nigri 15.5; Herba Cayatiae Japonicae 11; Rhizoma Dioscoreae 14.5; Herba Christiae Obcordatae 13.5).
3. a kind of Chinese medicine composition for the treatment of acute nephritis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, decoct with water, big fire is heated to boiling, continue 10 minutes, then add step (1) made crude drug, turn little fire and decoct 15-25 minute (preferably: turn little fire and decoct 17-23 minute; Be more preferably: turn little fire and decoct 20 minutes), filter, collect filtrate;
(5) made to step (2) (3) crude drug is pulverized, add in step (4) made filtrate, stir, obtain decoction.
4. a kind of preparation method for the treatment of the Chinese medicine composition decoction of acute nephritis as claimed in claim 3, is characterized in that, the 5-8 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 6-7 that amount of water is boiled crude drug quality doubly; Be more preferably: amount of water is 6.5 times of boiled crude drug quality).
5. a kind of Chinese medicine composition for the treatment of acute nephritis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) to decoct, big fire is heated to boiling, continues 10 minutes, turn little fire to decoct, filter, collect filtrate, heating concentrated filtrate is to thick paste;
(5) pulverized by made to step (1) (2) (3) crude drug, mix, add adjuvant, pill block, pill bar with step (4) gained thick paste, segmentation granulating, dry packing, obtains pill.
6. a kind of preparation method for the treatment of the Chinese medicine composition pill of acute nephritis as claimed in claim 5, is characterized in that, step (4) turn little fire decoct 15-25 minute (preferred: to turn little fire and decoct 17-23 minute; Be more preferably: turn little fire and decoct 20 minutes).
7. a kind of Chinese medicine composition for the treatment of acute nephritis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) to decoct, big fire is heated to boiling, continues 10 minutes, turn little fire to decoct 20 minutes, filter, collect filtrate, this filtrate of spraying dry;
(5) by step (1) (2) (3) (4) made crude drug and dry thing, pulverize and sieve, obtain powder.
8. a kind of preparation method for the treatment of the Chinese medicine composition composition powders of acute nephritis as claimed in claim 7, is characterized in that, it is (preferred: to pulverize 160-200 mesh sieve that step (5) pulverized 140-220 mesh sieve; Be more preferably: pulverized 180 mesh sieves).
9. a kind of Chinese medicine composition for the treatment of acute nephritis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get the Radix Paeoniae Alba, Caulis Clematidis Armandii, Radix Puerariae and Radix Polygoni Ciliinerve to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Herba Hydrocotyles, Herba Bidentis Bipinnatae, Herba Solani Nigri and Herba Cayatiae Japonicae wash quickly clean, drench into refined honey, mix thoroughly and be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, dry;
(3) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, smashs to pieces, dries;
(4) by Radix Habenariae Delavayi, Rhizoma Chuanxiong, Radix Rhododendri, Rhizoma Cimicifugae and Herba Christiae Obcordatae removing impurity, clean, be placed in non iron container, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times) to decoct, big fire is heated to boiling, continues 10 minutes, turn little fire to decoct 20 minutes, filter, collect filtrate, this filtrate of spraying dry;
(5) by step (1) (2) (3) (4) made crude drug and dry thing, pulverized 140 mesh sieves, obtained medicated powder, then added adjuvant cane sugar powder, and be packed in capsule according to the metering of 0.45g/ grain, obtain capsule.
10. a kind of preparation method for the treatment of the Chinese medicinal composition capsules agent of acute nephritis as claimed in claim 9, it is characterized in that, the amount of step (5) adjuvant cane sugar powder is the 0.2-0.4 of medicated powder quality doubly (preferred: the amount of adjuvant cane sugar powder is 0.3 times of medicated powder quality).
CN201510198634.7A 2015-04-24 2015-04-24 Traditional Chinese medicine composition for treating acute nephritis and preparation method thereof Pending CN104771585A (en)

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