CN104800630A - Traditional Chinese medicine preparation for treating acute nephritis - Google Patents

Traditional Chinese medicine preparation for treating acute nephritis Download PDF

Info

Publication number
CN104800630A
CN104800630A CN201510197765.3A CN201510197765A CN104800630A CN 104800630 A CN104800630 A CN 104800630A CN 201510197765 A CN201510197765 A CN 201510197765A CN 104800630 A CN104800630 A CN 104800630A
Authority
CN
China
Prior art keywords
herba
minute
dry
parts
minutes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510197765.3A
Other languages
Chinese (zh)
Inventor
王立昌
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201510197765.3A priority Critical patent/CN104800630A/en
Publication of CN104800630A publication Critical patent/CN104800630A/en
Pending legal-status Critical Current

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine preparation for treating acute nephritis. The traditional Chinese medicine preparation is made of the following drug substances by weight: 10 to 15 parts of poria cocos, 8 to 13 parts of clematidis armandii caulis, 7 to 12 parts of japanese cayratia herb, 12 to 18 parts of yam, 9 to 13 parts of habenaria delavayi finet, 11 to 16 parts of dogwood, 7 to 11 parts of pteroxygonum giraldii damm. et diels, 12 to 17 parts of fructus forsythiae, 10 to 14 parts of corn silk, 11 to 15 parts of stellaria yunnanensis franch., 6 to 9 parts of hydrocotyle sibthorpioides lam., 8 to 13 parts of herba ainsliaeae ovovatae, 7 to 15 parts of bunge corydalis herb, and 10 to 15 parts of sticktight. The traditional Chinese medicine preparation is obtained according to over years of clinical practices, and has the advantages of clearing heat, promoting diuresis, removing toxicity for detumescence, and tonifying the kidney, is obvious in curative effect, and can be used for treating both symptoms and root causes.

Description

The Chinese medicine for the treatment of acute nephritis
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to the Chinese medicine for the treatment of acute nephritis.
Background technology
Acute nephritis (that is: acute glomerulonephritis) is a kind of both sides kidney diffusivity glomerular epithelial cell caused owing to infecting rear allergy is main acute illness.Its feature is Acute onset, and hematuria, albuminuria, edema and hypertension can accompany transient azotemia, has spontaneous recovery tendency.After being common in streptococcal infection, and other antibacterials, virus and parasitic infection also can cause.Acute nephritis is more common in child, male.Usually 1 ~ 3 week onset after forerunner infects, induce the time of body generation needed for immune complex after being equivalent to pathogenic antigens initial immunity incubation period, the incubation period of respiratory tract infection person is short compared with skin infection person.Primary disease onset is comparatively anxious, and state of an illness weight differs, and the lighter is Subclinical (only having routine urinalysis extremely); Typical case person is performance in acute nephritic syndrome, and comprise hematuria, haemproteins, edema, hypertension or renal dysfunction etc., serious symptom person acute renal failure can occur.
Publication No. CN 102274416 A(application number 201110207748.5) Chinese patent literature disclose a kind of Chinese medicine for the treatment of acute nephritis.This Chinese medicine, composes according to a certain number of weight copies for active component with Rhizoma Imperatae, Herba Polygoni Avicularis, Radix Sophorae Flavescentis, Radix Arnebiae (Radix Lithospermi), Herba Lysimachiae, Stigma Maydis, Herba Ecliptae, Herba Leonuri, the Fructus Kochiae, Retinervus Luffae Fructus, Fructus Gardeniae, Herba Hedyotidis Diffusae, Semen sojae atricolor, Herba Menthae, Herba Taraxaci and Herba Xanthii.Publication No. CN 103479915 A(application number 201310425441.1) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of acute nephritis and preparation method thereof.This Chinese medicine composition is prepared from by the raw material comprising following weight portion: Herba Ephedrae, Fructus Forsythiae, Semen Phaseoli, Flos Lonicerae, Herba Taraxaci, Herba Violae, Rhizoma Imperatae, rubia, Herba Agrimoniae.Publication No. CN 103330864 A(application number 201310287316.9) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of acute nephritis and preparation method thereof, be made up of the crude drug of following weight portion: Rhizoma Dioscoreae 7-13 part, Zaocys 7-13 part, Radix Rehmanniae 7-13 part, Radix Paeoniae Rubra 7-13 part, Herba Cirsii 7-13 part, Herba Leonuri 7-13 part, Herba Lobeliae Chinensis 5-9 part, Flos Lonicerae 5-9 part, Radix Isatidis 5-9 part, Fructus Forsythiae 5-9 part, Radix Astragali 5-9 part, Polyporus 5-9 part, Rhizoma Alismatis 3-7 part, Periostracum Cicadae 3-7 part, Rhizoma Atractylodis 3-7 part, Rhizoma Atractylodis Macrocephalae 3-7 part, Semen Coicis 3-7 part, Radix Saposhnikoviae 2-4 part, Cortex Moutan 2-4 part, Cortex Acanthopancis 2-4 part, Pericarpium Arecae 2-4 part, Pericarpium Citri Reticulatae 2-4 part, Fructus Arctii 2-4 part, Radix Sophorae Tonkinensis 2-4 part, Rhizoma Cimicifugae 2-4 part, Radix Platycodonis 2-4 part, Cortex Dictamni 2-4 part, Fructus Kochiae 2-4 part, Fructus Cnidii 2-4 part, Herba Eupatorii 2-4 part, Poria 2-4 part, Radix Angelicae Sinensis 2-4 part.
Western medicine acute nephritis mostly is antibiotic, infringement health, and side effect is large, and Chinese traditional treatment safety is high, focuses on the Repair and protection of kidney, has effect for the treatment of both the principal and secondary aspects of a disease, therefore need to work out formula more how evident in efficacy.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take the Chinese medicine of the wide treatment acute nephritis of safe and applicable.
Technical scheme of the present invention is:
The Chinese medicine for the treatment of acute nephritis, is prepared from primarily of following bulk drugs, is mass parts: Poria 10-15; Caulis Clematidis Armandii 8-13; Herba Cayatiae Japonicae 7-12; Rhizoma Dioscoreae 12-18; Radix Habenariae Delavayi 9-13; Fructus Corni 11-16; Radix Polygoni Ciliinerve 7-11; Fructus Forsythiae 12-17; Stigma Maydis 10-14; Radix Stellariae Yunnanensis 11-15; Herba Hydrocotyles 6-9; Herba Ainsliaeae ovovatae 8-13; Herba Violae 7-15; Herba Bidentis Bipinnatae 10-15.
Preferred version is, Poria 11-14; Caulis Clematidis Armandii 9-12; Herba Cayatiae Japonicae 9-10; Rhizoma Dioscoreae 14-16; Radix Habenariae Delavayi 10-12; Fructus Corni 12-15; Radix Polygoni Ciliinerve 8-10; Fructus Forsythiae 13-16; Stigma Maydis 11-13; Radix Stellariae Yunnanensis 12-14; Herba Hydrocotyles 7-8; Herba Ainsliaeae ovovatae 9-12; Herba Violae 9-13; Herba Bidentis Bipinnatae 11-14.
More preferably, Poria 12.5; Caulis Clematidis Armandii 10.5; Herba Cayatiae Japonicae 9.5; Rhizoma Dioscoreae 15; Radix Habenariae Delavayi 11; Fructus Corni 13.5; Radix Polygoni Ciliinerve 9; Fructus Forsythiae 14.5; Stigma Maydis 12; Radix Stellariae Yunnanensis 13; Herba Hydrocotyles 7.5; Herba Ainsliaeae ovovatae 10.5; Herba Violae 11; Herba Bidentis Bipinnatae 12.5.
The Chinese medicine of described treatment acute nephritis, be made into pharmaceutically acceptable syrup, its preparation method is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 18-26 minute (preferred: little fiery continuous heating 20-24 minute; Be more preferably: little fiery continuous heating 22 minutes), take out, dry, smash to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 2-4 minute (preferred: to soak 3 minutes), take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, add water and do not have medical material 4cm to soak 10 minutes, intense fire is heated to boiling, turns little fire and decocts 20-32 minute (preferably: little fire decocts 22-30 minute; Be more preferably: little fire decocts 26 minutes), filter, collect filtrate;
(5) step (1) (2) (3) made crude drug is pulverized, be added in step (4) gained filtrate, be evaporated to clear paste, add simple syrup, stir, obtain syrup.
The preparation method of the Chinese medicine syrup of described treatment acute nephritis, the amount of step (5) simple syrup is that doubly (amount of preferred simple syrup is 0.4-0.5 times of clear paste quality to the 0.3-0.6 of clear paste quality; Be more preferably: the amount of simple syrup is 0.45 times of clear paste quality).
The Chinese medicine of described treatment acute nephritis, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 18-26 minute (preferred: little fiery continuous heating 20-24 minute; Be more preferably: little fiery continuous heating 22 minutes), take out, dry, smash to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 2-4 minute (preferred: to soak 3 minutes), take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, soak 10 minutes, intense fire is heated to boiling, add step (1) (3) made crude drug again, turn little fire and decoct 20-32 minute (preferably: little fire decocts 22-30 minute; Be more preferably: little fire decocts 26 minutes), filter, collect filtrate;
(5) step (2) made crude drug is mixed with step (4) gained filtrate, stir, obtain decoction.
The preparation method of the Chinese medicine decoction of described treatment acute nephritis, the 6-9 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 7-8 that amount of water is boiled crude drug quality is doubly; Be more preferably: amount of water is 7.5 times of boiled crude drug quality).
The Chinese medicine of described treatment acute nephritis, be made into pharmaceutically acceptable granule, its preparation method is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 18-26 minute (preferred: little fiery continuous heating 20-24 minute; Be more preferably: little fiery continuous heating 22 minutes), take out, dry, smash to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 2-4 minute (preferred: to soak 3 minutes), take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, add water and soak 10 minutes into boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, add step (1) (3) made crude drug again, turn little fire to decoct, filter, collect filtrate;
(5) concentration step (4) gained filtrate is to thick paste, mixes, add adjuvant, make soft material with step (2) made crude drug, granulates, dry, packs and obtains granule.
The preparation method of the Chinese medicine granule of described treatment acute nephritis, the little fire of step (4) decocts 20-32 minute (preferably: little fire decocts 22-30 minute; Be more preferably: little fire decocts 26 minutes).
The Chinese medicine of described treatment acute nephritis, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 18-26 minute (preferred: little fiery continuous heating 20-24 minute; Be more preferably: little fiery continuous heating 22 minutes), take out, dry, smash to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 2-4 minute (preferred: to soak 3 minutes), take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, add water and soak 10 minutes into boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, turns little fire and decocts 20-32 minute (preferably: little fire decocts 22-30 minute; Be more preferably: little fire decocts 26 minutes), filter, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverizes and sieves together with step (1) (2) (3) made crude drug, according to the preparation method of tablet, is crushed to round sheet dosage form (every is 0.35g containing medicated powder amount).
The preparation method of the Chinese medicine tablet of described treatment acute nephritis, it is (preferred: to pulverize 150-190 mesh sieve that step (5) pulverized 130-210 mesh sieve; Be more preferably: pulverized 170 mesh sieves).
The Chinese medicine scientific formulation for the treatment of acute nephritis provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, evident in efficacy, and cure rate is high, effectively can reduce relapse rate;
2, products obtained therefrom of the present invention has effect of clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, replenishing kidney, strengthening waist;
3, Chinese crude drug selected by the present invention, safety has no side effect, can long-term taking, tonification health.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the Chinese medicine for the treatment of acute nephritis, is prepared from (every part of 10g) primarily of following bulk drugs: 10 parts, Poria, Caulis Clematidis Armandii 8 parts, Herba Cayatiae Japonicae 7 parts, Rhizoma Dioscoreae 12 parts, Radix Habenariae Delavayi 9 parts, Fructus Corni 11 parts, Radix Polygoni Ciliinerve 7 parts, Fructus Forsythiae 12 parts, Stigma Maydis 10 parts, Radix Stellariae Yunnanensis 11 parts, Herba Hydrocotyles 6 parts, Herba Ainsliaeae ovovatae 8 parts, Herba Violae 7 parts, Herba Bidentis Bipinnatae 10 parts.The preparation method of the Chinese medicine syrup of above-mentioned treatment acute nephritis is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 12 minutes, transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, dries, smashs to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 3 minutes, take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, add water and do not have medical material 4cm to soak 10 minutes, intense fire is heated to boiling, turns little fire and decocts 26 minutes, filter, collect filtrate;
(5) step (1) (2) (3) made crude drug is pulverized, be added in step (4) gained filtrate, be evaporated to clear paste, add the simple syrup of clear paste quality 0.45 times, stir, obtain syrup.
embodiment 2the Chinese medicine for the treatment of acute nephritis, is prepared from (every part of 10g) primarily of following bulk drugs: 15 parts, Poria, Caulis Clematidis Armandii 13 parts, Herba Cayatiae Japonicae 12 parts, Rhizoma Dioscoreae 18 parts, Radix Habenariae Delavayi 13 parts, Fructus Corni 16 parts, Radix Polygoni Ciliinerve 11 parts, Fructus Forsythiae 17 parts, Stigma Maydis 14 parts, Radix Stellariae Yunnanensis 15 parts, Herba Hydrocotyles 9 parts, Herba Ainsliaeae ovovatae 13 parts, Herba Violae 15 parts, Herba Bidentis Bipinnatae 15 parts.The preparation method of the Chinese medicine decoction of above-mentioned treatment acute nephritis is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 12 minutes, transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, dries, smashs to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 3 minutes, take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, add the water soaking 10 minutes of boiled crude drug quality 7.5 times, intense fire is heated to boiling, add step (1) (3) made crude drug again, turn little fire to decoct 26 minutes, filter, collect filtrate;
(5) step (2) made crude drug is mixed with step (4) gained filtrate, stir, obtain decoction.
Model case: xxx, male, 19 years old.Main suit: edema of pair of lower extremities increases the weight of, with the puffiness of the eyes for ten days; Medical history: patient caught a cold before ten days accidentally, once occurred symptom of diarrhea, one day three times, after infusion treatment, flu, symptom of diarrhea disappear, rear discovery edema of pair of lower extremities, do not take notice of, recent swelling increases the weight of, and the puffiness of the eyes is obvious, examination in hospital then, urine protein (10), occult blood (10), routine blood test is normal, is diagnosed as acute glomerulonephritis.
Take this example gained decoction, each 120-160ml, warmly to take, one day twice, within 15 days, be a course for the treatment of, after patient takes one week, edema alleviates gradually, uncomfortable disease disappears substantially, after adhering to taking a course for the treatment of, patient body is clearly better, further consultation inspection, routine urinalysis all recovers normal, and patient fully recovers.
embodiment 3the Chinese medicine for the treatment of acute nephritis, is prepared from (every part of 10g) primarily of following bulk drugs: 11 parts, Poria, Caulis Clematidis Armandii 9 parts, Herba Cayatiae Japonicae 9 parts, Rhizoma Dioscoreae 14 parts, Radix Habenariae Delavayi 10 parts, Fructus Corni 12 parts, Radix Polygoni Ciliinerve 8 parts, Fructus Forsythiae 13 parts, Stigma Maydis 11 parts, Radix Stellariae Yunnanensis 12 parts, Herba Hydrocotyles 7 parts, Herba Ainsliaeae ovovatae 9 parts, Herba Violae 9 parts, Herba Bidentis Bipinnatae 11 parts.The preparation method of the Chinese medicine granule of above-mentioned treatment acute nephritis is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 12 minutes, transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, dries, smashs to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 3 minutes, take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, add water into the water soaking 10 minutes of boiled crude drug quality 7 times, intense fire is heated to boiling, add step (1) (3) made crude drug again, turn little fire to decoct 26 minutes, filter, collect filtrate;
(5) concentration step (4) gained filtrate is to thick paste, mixes, add adjuvant, make soft material with step (2) made crude drug, granulates, dry, packs and obtains granule.
Model case: xxx, male, 7 years old.Medical history: tonsil inflammation before patient's first quarter moon, after treatment, recovery from illness, chances on the puffiness of the eyes, within the next few days with the symptom such as loss of appetite, nausea and vomiting, medical inspection, edema of lower limbs, hypourocrinia, urine is muddy, urine protein (++), gross hematuria, blood pressure 130/95mmHg, is diagnosed as acute glomerulonephritis.
Recommend to take this example gained granule, each 3-4g, warm boiled water through people, one day twice 15 days is a course for the treatment of, after patient takes a course for the treatment of, Nausea and vomiting symptom is eliminated, and appetite is normal, and urine volume increases, after continuing to take a course for the treatment of, urine color is normal, further consultation inspection, and indices is all without exception, in drug withdrawal half a year, there is not sequela in patient.
embodiment 4the Chinese medicine for the treatment of acute nephritis, is prepared from (every part of 10g) primarily of following bulk drugs: 14 parts, Poria, Caulis Clematidis Armandii 12 parts, Herba Cayatiae Japonicae 10 parts, Rhizoma Dioscoreae 16 parts, Radix Habenariae Delavayi 12 parts, Fructus Corni 15 parts, Radix Polygoni Ciliinerve 10 parts, Fructus Forsythiae 16 parts, Stigma Maydis 13 parts, Radix Stellariae Yunnanensis 14 parts, Herba Hydrocotyles 8 parts, Herba Ainsliaeae ovovatae 12 parts, Herba Violae 13 parts, Herba Bidentis Bipinnatae 14 parts.The preparation method of the Chinese medicine tablet of above-mentioned treatment acute nephritis is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 12 minutes, transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, dries, smashs to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 3 minutes, take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, add water into the water soaking 10 minutes of boiled crude drug quality 7 times, intense fire is heated to boiling, turns little fire and decocts 26 minutes, filter, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverized 170 mesh sieves together with step (1) (2) (3) made crude drug, according to the preparation method of tablet, was crushed to round sheet dosage form (every is 0.35g containing medicated powder amount).
Model case: xxx, women, 49 years old.Medical history: patient occurred facial edema without obvious inducement before three days, urine color is rubescent, and Progressive symmetric erythrokeratodermia hypourocrinia, with heating paresthesia, through urine examination, urine protein (++), erythrocyte 10 ~ 12/ high power, leukocyte 1 ~ 4/ high power, creatinine 324.60umol/L, is diagnosed as acute nephritis.
Accept doctor advised, use traditional Chinese medical science expectant treatment, take this example gained tablet, each 3-4 grain, warm boiled water, one day twice, within 15 days, be a course for the treatment of, after patient takes three days, temperature recovery is normal, after adhering to a course for the treatment of, edema disappears, and the symptom such as hematuria, oliguria alleviates, after continuing to take a course for the treatment of, return hospital's further consultation, routine urinalysis is all normal, patient fully recovers, and follows up a case by regular visits in two years, does not recur.
embodiment 5the Chinese medicine for the treatment of acute nephritis, is prepared from (every part of 10g) primarily of following bulk drugs: 12.5 parts, Poria, Caulis Clematidis Armandii 10.5 parts, Herba Cayatiae Japonicae 9.5 parts, Rhizoma Dioscoreae 15 parts, Radix Habenariae Delavayi 11 parts, Fructus Corni 13.5 parts, Radix Polygoni Ciliinerve 9 parts, Fructus Forsythiae 14.5 parts, Stigma Maydis 12 parts, Radix Stellariae Yunnanensis 13 parts, Herba Hydrocotyles 7.5 parts, Herba Ainsliaeae ovovatae 10.5 parts, Herba Violae 11 parts, Herba Bidentis Bipinnatae 12.5 parts.The preparation method of the Chinese medicine syrup of above-mentioned treatment acute nephritis is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 12 minutes, transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 22 minutes, takes out, dries, smashs to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 3 minutes, take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, add water and do not have medical material 4cm to soak 10 minutes, intense fire is heated to boiling, turns little fire and decocts 26 minutes, filter, collect filtrate;
(5) step (1) (2) (3) made crude drug is pulverized, be added in step (4) gained filtrate, be evaporated to clear paste, add the simple syrup of clear paste quality 0.45 times, stir, obtain syrup.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Poria: base is former: be the dry sclerotia of Polyporaceae plant Poria.Nature and flavor with return through: sweet, light, flat.GUIXIN, lung, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, spleen invigorating, effect of mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Caulis Clematidis Armandii: base is former: be the dry rattan of ranunculaceae plant Herba Clematidis Lasiandrae or Clematis montana.Nature and flavor with return through: bitter, cold.GUIXIN, small intestinal, urinary bladder channel.Function with cure mainly: inducing diuresis for treating stranguria syndrome, clear away heart-fire relieving restlessness, stimulating milk secretion of stimulating the menstrual flow.For stranguria, edema, vexed dark coloured urine, aphtha of the mouth and tongue, amenorrhea breast is few, damp and hot arthralgia pain.
Herba Cayatiae Japonicae: base is former: be herb or the root of vitaceae Herba Cayatiae Japonicae.Nature and flavor: bitter; Acid; Cold.Gui Jing: the heart; Liver; Stomach warp.Function cures mainly: clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.Main pyretic toxicity carbuncle; Furuncle; Erysipelas; Laryngopharynx swelling and pain; Snake bite and insect sting; Burn due to hot liquid or fire; Rheumatic arthralgia; Jaundice; Dysentery; Nebulousurine; Hematuria.
Rhizoma Dioscoreae: nature and flavor: sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, effect of the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Radix Habenariae Delavayi: base is former: be the tuber of the beautiful phoenix flower of the thick lobe of orchid.Nature and flavor: sweet; Micro-pungent; Temperature.Gui Jing: kidney channel.Function cures mainly: replenishing kidney, strengthening waist; Regulating QI to relieve pain.Main lumbago due to renal deficiency; Hernia; The stagnation of QI is had a stomachache.
Fructus Corni: base is former: be the sarcocarp of Cornaceae plant Fructus Corni.Nature and flavor with return through: sour, puckery, tepor.Return liver, kidney channel.Have liver and kidney tonifying, effect of arresting collape syndrome by astringents, for dizzy ear toot, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse, interior-heat is quenched one's thirst.
Radix Polygoni Ciliinerve: base is former: be the tuber of polygonaceae plant floating and thready pulse knotweed.Nature and flavor: bitter in the mouth is micro-puckery, cool in nature.Gui Jing: lung; Large intestine; Liver Channel.Function cures mainly: raw use: anti-inflammation, pleasantly invigorates blood circulation, cooling blood for hemostasis, tranquillizing to relieve muscle spasm, pain relieving, and antidiarrheal, promotes ulcer healing; Salt person the kidney invigorating, vinegar person stops blooding, alkali person stomach invigorating.Treating tonsillitis, enteritis, gastritis, Peptic Ulcers, bacillary dysentery, ascariasis of biliary tract, trauma infection contamination, cellulitis, carbuncle furuncle, purulent, urinary system infection, menoxenia, metrorrhagia, traumatic hemorrhage, spit blood, epistaxis, has blood in stool, traumatic injury, lumbago, skelalgia of rheumatism.
Fructus Forsythiae: nature and flavor with return through: bitter, be slightly cold.Return lung, the heart, small intestine meridian; There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of dispelling wind and heat pathogens; For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warm people battalion, high hot excessive thirst, coma sends out speckle, the puckery pain of pyretic stranguria.
Stigma Maydis: base is former: be the zeistic style of grass and stigma.Nature and flavor: sweet in the mouth; Light; Property is put down.Gui Jing: kidney; Stomach; Liver; Gallbladder meridian.Function cures mainly: inducing diuresis to remove edema; Liver heat removing function of gallbladder promoting.Main edema; Dribbling urination; Jaundice; Cholecystitis; Cholelithiasis; Hypertension; Diabetes; Galactostasis.
Radix Stellariae Yunnanensis: another name wheat ginseng, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), large Herba malachii aquatici.Base is former: be the root of pinkwort Yunnan Herba stellariae mediae.Summer, autumn gather.Nature and flavor: sweet; Property is put down.Gui Jing: liver; Spleen; Kidney channel.Function cures mainly: strengthening spleen and nourishing blood; The liver and the kidney tonifying; Detumescence.Main anemia; Spirit is deficient; Dizzy nervous; Tinnitus dim eyesight; Hectic fever; Seminal emission; Menoxenia; Leukorrhagia; Fracture; Mastitis.
Herba Hydrocotyles: base is former: be the herb of samphire Herba Hydrocotyles and Hydrocotyle sibthorpioides lam.Var.Batvachium (Hand.-Mazz.) et shan..Chemical analysis: herb is containing flavones ingredient: Quercetin, Quercetin-3-galactoside, isorhamnetin, Quercetin-3-O-β-D-(6-caffeoyl galactoside).Again containing wooden body composition, left-handed sesamin and Mus Body components: stigmasterol.Not containing coumarin.Nature and flavor: acrid in the mouth; Micro-hardship; Cool in nature.Function cures mainly: clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.Main jaundice; Dysentery; Edema; Stranguria; Corneal nebula; Larynx swells; Carbuncle sore tumefacting virus; Herpes zoster; Traumatic injury.
Herba Ainsliaeae ovovatae: base is former: be the herb of feverfew Acanthopanax obovatus Hoo Ainsliaea fragrans Champ..Nature and flavor: mildly bitter flavor; Cool in nature.Function cures mainly: heat clearing away; Dampness removing; Cough-relieving; Removing toxic substances.Main urgency; Chronic renal fire; Nephropyelitis; Cystitis; Bronchitis; Dysentery; Weapons are hindered.
Herba Violae: base is former: be Violaceae Chinese violet, Herba Violae japonicae; The whole herb with root of leguminous plant Gueldenstaedtia verna, little Gueldenstaedtia verna or gentianaceae plant Gentiana.Chemical analysis: Herba Violae herb containing glycoside, flavonoid, wax (esters for cerinic acid and unsaturated acids etc.), the also content of wax in spending, containing saturated acid (being mainly cerinic acid) 34.9% in wax, unsaturated acids 5.8%, alcohols 10.3%, hydrocarbon about 47%.Nature and flavor: bitter, cold.Gui Jing: enter the heart, Liver Channel.Function cures mainly: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Control furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.
Herba Bidentis Bipinnatae: base is former: be the herb of feverfew Herba Bidentis Bipinnatae.Chemical analysis: herb is containing alkaloid, tannin, Saponin, flavonoid glycoside.Stem and leaf is containing volatile oil, tannin, amaroid, choline etc.Fruit oil-containing 27.3%.Nature and flavor: bitter in the mouth; Cold nature.Function cures mainly: heat-clearing and toxic substances removing; Expelling wind and removing dampness; Promoting blood circulation and detumescence.Main throat; Swell and ache; Have loose bowels; Dysentery; Jaundice; Intestinal carbuncle; Furuncle swelling toxin; Serpentis is early bitten; Rheumatic arthralgia; Traumatic injury.
test example 1the clinical practice of the Chinese medicine (embodiment 5) of gained treatment acute nephritis of the present invention:
Choose crowd: in June, 2013 in December ,-2014, according to medical case history, patient 328 example of acute nephritis is diagnosed as four hospital's screenings, wherein male patient 217 example, female patient 111 example, the age is minimum is 5 years old, be 65 years old to the maximum, 28.7 ± 1.4 years old mean age, with 8-18 year maximum, the course of disease 3 days-4 months.Diagnosis basis: 1. morbidity is anxious, and state of an illness weight differs, and the lighter can without clinical symptoms, most of prognosis bona, and the course of disease is generally within 1 year; 2. have albuminuria, hematuria (under mirror or gross hematuria), cylinderuria, often have edema, hypertension or of short duration azotemia, ultrasound diagnosis kidney is without reducing; 3. some cases has acute meningitis from Streptococcus pneumoniae history, 1-3 week morbidity after infection.
Before test, patient is divided into two groups at random, experimental group 210 example and matched group 118 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, one day twice, each 6-10g, warm boiled water, within 15 days, is a course for the treatment of; Matched group takes other conventional medicines (shenyankangfu tablet, SHENFUKANG JIAONANG, SHILINTONG PIAN etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: the Sxs such as edema, oliguria, hematuria, hypertension disappear, and urine examination is negative; (2) effective: the Sxs such as edema, oliguria, hematuria, hypertension disappear or major part disappears, urine protein one (+) below, erythrocyte L EssT.LTssT.LT 15/high power lens, erythrocyte cuts down more than one (+); (3) invalid: symptom and sign are not obviously improved, and urine examination is positive.
Clinical effectiveness: after the taking medicine of three courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, the healing patient of experimental group is 134 examples, and cure rate is 63.8%, effective patient is 71 examples, and effective percentage is 33.8%, and total effective rate is 97.6%, and the patient that matched group is cured is 57 examples, cure rate is 48.3%, and effective patient is 38 examples, and effective percentage is 32.2%, total effective rate 80.5%, significantly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.
Before and after two groups of patient treatments uncomfortable disease to improve number of cases as shown in table 2:
As shown in Table 2, before and after treatment, the uncomfortable disease of patient of experimental group is obviously improved, and therapeutic effect is obviously better than matched group, and products obtained therefrom treating both the principal and secondary aspects of a disease of the present invention is described, effectively alleviates clinical uncomfortable disease.
The Chinese medicine used in the present invention, Poria can promoting diuresis to eliminate damp pathogen, and Caulis Clematidis Armandii and Stigma Maydis can inducing diuresis for treating stranguria syndrome, Herba Cayatiae Japonicae, Herba Hydrocotyles and Herba Bidentis Bipinnatae can removing toxic substances and promoting subsidence of swelling, and Rhizoma Dioscoreae can spleen reinforcing nourishing the stomach, and Radix Habenariae Delavayi can replenishing kidney, strengthening waist, Fructus Corni and Radix Stellariae Yunnanensis can liver and kidney tonifying, Radix Polygoni Ciliinerve can anti-inflammation, and Fructus Forsythiae can dispersing swelling and dissipating binds, and Herba Ainsliaeae ovovatae and Herba Violae can clearing away heat-damp and promoting diuresis, multiple medical material synergism, play effect of clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, replenishing kidney, strengthening waist altogether, effectively eliminate uncomfortable disease, heighten the effect of a treatment.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat the Chinese medicine of acute nephritis, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Poria 10-15; Caulis Clematidis Armandii 8-13; Herba Cayatiae Japonicae 7-12; Rhizoma Dioscoreae 12-18; Radix Habenariae Delavayi 9-13; Fructus Corni 11-16; Radix Polygoni Ciliinerve 7-11; Fructus Forsythiae 12-17; Stigma Maydis 10-14; Radix Stellariae Yunnanensis 11-15; Herba Hydrocotyles 6-9; Herba Ainsliaeae ovovatae 8-13; Herba Violae 7-15; Herba Bidentis Bipinnatae 10-15.
2. the Chinese medicine for the treatment of acute nephritis as claimed in claim 1, is characterized in that, Poria 11-14; Caulis Clematidis Armandii 9-12; Herba Cayatiae Japonicae 9-10; Rhizoma Dioscoreae 14-16; Radix Habenariae Delavayi 10-12; Fructus Corni 12-15; Radix Polygoni Ciliinerve 8-10; Fructus Forsythiae 13-16; Stigma Maydis 11-13; Radix Stellariae Yunnanensis 12-14; Herba Hydrocotyles 7-8; Herba Ainsliaeae ovovatae 9-12; Herba Violae 9-13; Herba Bidentis Bipinnatae 11-14(is preferably: Poria 12.5; Caulis Clematidis Armandii 10.5; Herba Cayatiae Japonicae 9.5; Rhizoma Dioscoreae 15; Radix Habenariae Delavayi 11; Fructus Corni 13.5; Radix Polygoni Ciliinerve 9; Fructus Forsythiae 14.5; Stigma Maydis 12; Radix Stellariae Yunnanensis 13; Herba Hydrocotyles 7.5; Herba Ainsliaeae ovovatae 10.5; Herba Violae 11; Herba Bidentis Bipinnatae 12.5).
3. the Chinese medicine of the treatment acute nephritis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable syrup, its preparation method is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 18-26 minute (preferred: little fiery continuous heating 20-24 minute; Be more preferably: little fiery continuous heating 22 minutes), take out, dry, smash to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 2-4 minute (preferred: to soak 3 minutes), take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, add water and do not have medical material 4cm to soak 10 minutes, intense fire is heated to boiling, turns little fire and decocts 20-32 minute (preferably: little fire decocts 22-30 minute; Be more preferably: little fire decocts 26 minutes), filter, collect filtrate;
(5) step (1) (2) (3) made crude drug is pulverized, be added in step (4) gained filtrate, be evaporated to clear paste, add simple syrup, stir, obtain syrup.
4. the preparation method of the Chinese medicine syrup for the treatment of acute nephritis as claimed in claim 3, is characterized in that, the amount of step (5) simple syrup is that doubly (amount of preferred simple syrup is 0.4-0.5 times of clear paste quality to the 0.3-0.6 of clear paste quality; Be more preferably: the amount of simple syrup is 0.45 times of clear paste quality).
5. the Chinese medicine of the treatment acute nephritis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 18-26 minute (preferred: little fiery continuous heating 20-24 minute; Be more preferably: little fiery continuous heating 22 minutes), take out, dry, smash to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 2-4 minute (preferred: to soak 3 minutes), take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, soak 10 minutes, intense fire is heated to boiling, add step (1) (3) made crude drug again, turn little fire and decoct 20-32 minute (preferably: little fire decocts 22-30 minute; Be more preferably: little fire decocts 26 minutes), filter, collect filtrate;
(5) step (2) made crude drug is mixed with step (4) gained filtrate, stir, obtain decoction.
6. the preparation method of the Chinese medicine decoction for the treatment of acute nephritis as claimed in claim 5, is characterized in that, the 6-9 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 7-8 that amount of water is boiled crude drug quality doubly; Be more preferably: amount of water is 7.5 times of boiled crude drug quality).
7. the Chinese medicine of the treatment acute nephritis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable granule, its preparation method is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 18-26 minute (preferred: little fiery continuous heating 20-24 minute; Be more preferably: little fiery continuous heating 22 minutes), take out, dry, smash to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 2-4 minute (preferred: to soak 3 minutes), take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, add water and soak 10 minutes into boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, add step (1) (3) made crude drug again, turn little fire to decoct, filter, collect filtrate;
(5) concentration step (4) gained filtrate is to thick paste, mixes, add adjuvant, make soft material with step (2) made crude drug, granulates, dry, packs and obtains granule.
8. the preparation method of the Chinese medicine granule for the treatment of acute nephritis as claimed in claim 7, is characterized in that, the little fire of step (4) decocts 20-32 minute (preferably: little fire decocts 22-30 minute; Be more preferably: little fire decocts 26 minutes).
9. the Chinese medicine of the treatment acute nephritis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get Caulis Clematidis Armandii, Herba Cayatiae Japonicae, Radix Habenariae Delavayi, Radix Polygoni Ciliinerve, Fructus Forsythiae and Radix Stellariae Yunnanensis to clean, shave, did not have crude drug to soak into rice wine, sealing, and intense fire heats 8-16 minute (preferably: intense fire heating 10-14 minute; Be more preferably: intense fire heats 12 minutes), transfer slow fire to and be heated to rice wine and boil dry, take out, dry in the air cool;
(2) get Rhizoma Dioscoreae to clean, remove the peel, add crystal sugar water and decoct together, little fiery continuous heating 18-26 minute (preferred: little fiery continuous heating 20-24 minute; Be more preferably: little fiery continuous heating 22 minutes), take out, dry, smash to pieces;
(3) get Stigma Maydis removing impurity, clean, put into rice vinegar and soak 2-4 minute (preferred: to soak 3 minutes), take out, dry, repeat once, dry in the air cool;
(4) Poria, Fructus Corni, Herba Hydrocotyles, Herba Ainsliaeae ovovatae, Herba Violae and Herba Bidentis Bipinnatae are cleaned, be placed in marmite, add water and soak 10 minutes into boiled crude drug quality 6-8 water doubly (preferred: the water adding boiled crude drug quality 7 times), intense fire is heated to boiling, turns little fire and decocts 20-32 minute (preferably: little fire decocts 22-30 minute; Be more preferably: little fire decocts 26 minutes), filter, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverizes and sieves together with step (1) (2) (3) made crude drug, according to the preparation method of tablet, is crushed to round sheet dosage form (every is 0.35g containing medicated powder amount).
10. the preparation method of the Chinese medicine tablet for the treatment of acute nephritis as claimed in claim 9, it is characterized in that, it is (preferred: to pulverize 150-190 mesh sieve that step (5) pulverized 130-210 mesh sieve; Be more preferably: pulverized 170 mesh sieves).
CN201510197765.3A 2015-04-24 2015-04-24 Traditional Chinese medicine preparation for treating acute nephritis Pending CN104800630A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510197765.3A CN104800630A (en) 2015-04-24 2015-04-24 Traditional Chinese medicine preparation for treating acute nephritis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510197765.3A CN104800630A (en) 2015-04-24 2015-04-24 Traditional Chinese medicine preparation for treating acute nephritis

Publications (1)

Publication Number Publication Date
CN104800630A true CN104800630A (en) 2015-07-29

Family

ID=53686111

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510197765.3A Pending CN104800630A (en) 2015-04-24 2015-04-24 Traditional Chinese medicine preparation for treating acute nephritis

Country Status (1)

Country Link
CN (1) CN104800630A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105902697A (en) * 2016-07-06 2016-08-31 林俊成 Traditional Chinese medicine preparation for treating acute nephritis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101732611A (en) * 2010-01-26 2010-06-16 王丽 Chinese medicament for treating purpuric nephritis
CN102940798A (en) * 2012-10-10 2013-02-27 肥西县中医院 Traditional Chinese medicine composition for treating nephrotic syndrome and preparation method thereof
CN104353047A (en) * 2014-11-24 2015-02-18 时成伍 Traditional Chinese medicine for treating nephritis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101732611A (en) * 2010-01-26 2010-06-16 王丽 Chinese medicament for treating purpuric nephritis
CN102940798A (en) * 2012-10-10 2013-02-27 肥西县中医院 Traditional Chinese medicine composition for treating nephrotic syndrome and preparation method thereof
CN104353047A (en) * 2014-11-24 2015-02-18 时成伍 Traditional Chinese medicine for treating nephritis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
江波: "清热养阴活血法治疗慢性肾炎血尿27例", 《湖北中医杂志》 *
胡必明: "自拟复肾汤治疗急性肾小球肾炎100例", 《中国现代药物应用》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105902697A (en) * 2016-07-06 2016-08-31 林俊成 Traditional Chinese medicine preparation for treating acute nephritis

Similar Documents

Publication Publication Date Title
CN102579912B (en) Chinese medicinal capsules special for treating acute mastitis and preparation method thereof
CN103520573B (en) Traditional Chinese medicine for treating liver depression and blood stasis syndrome type breast nodule diseases
CN103599496A (en) Traditional Chinese medicine for treatment of chronic gastritis
CN104800817A (en) Medicinal composition for treating dog rhinitis and preparation method thereof
CN104771585A (en) Traditional Chinese medicine composition for treating acute nephritis and preparation method thereof
CN104800630A (en) Traditional Chinese medicine preparation for treating acute nephritis
CN103536857B (en) Traditional Chinese medicine for treating flaccid paralysis
CN103816450B (en) A kind of Chinese medicine for the treatment of rheumatoid arthritis
CN104689205A (en) Traditional Chinese preparation for treating insomnia and dreamful sleep and preparation method thereof
CN105796992A (en) Oral liquid for effective treatment of oral ulcer
CN104922595A (en) Traditional Chinese medicinal preparation for herpes zoster and preparation method thereof
CN105079319A (en) Prescription for treating sciatica
CN105311564A (en) Preparation for treating lymph cancer and capable of soothing liver and relieving depression and preparing method of preparation
CN104873854A (en) Traditional Chinese medicine preparation for rteriolar nephrosclerosis and preparation method thereof
CN104825892A (en) Traditional Chinese medicine preparation for treating ovulatory bleeding and preparation method of traditional Chinese medicine preparation
CN104383361A (en) Traditional Chinese medicine preparation for treating acute infectious hepatitis
CN103505713B (en) Traditional Chinese medicine formula for treating disharmony between ying and wei syndrome muscle numbness disease
CN112675282A (en) Composition for treating pneumonia, preparation method and particles prepared by composition
CN104116991A (en) Traditional Chinese medicine preparation for treating radiation sickness and preparation method thereof
CN104435162A (en) Oral traditional Chinese medicine preparation for treating viral pneumonia
CN104225342A (en) Chinese herbal preparation for treating nephritis edema and preparation method thereof
CN115006506A (en) Ginseng preparation for nourishing and nourishing kidney and preparation method thereof
CN104208517A (en) Infant diarrhea rapid treating preparation
CN113546145A (en) Pill for treating hepatitis B
CN105535688A (en) Traditional Chinese medicine preparation for rapidly treating herpes zoster

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
EXSB Decision made by sipo to initiate substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information

Address after: 350200 Changle City, Fujian province unity District No. 7, No. 901, No.

Applicant after: Wang Lichang

Address before: 250000 Shanxi City, Ji'nan province central white horse road, No. 27, Shandong

Applicant before: Wang Lichang

COR Change of bibliographic data
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20150729