Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of syndrome of stagnation of liver qi and blood stasis type nodules of the breast disease, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing syndrome of stagnation of liver qi and blood stasis type nodules of the breast disease.
For achieving the above object, the present invention by the following technical solutions:
Treat a Chinese medicine for syndrome of stagnation of liver qi and blood stasis type nodules of the breast disease, it is characterized in that being prepared from by the medical material of following weight proportion:
Radix Bupleuri 10 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, 30 parts, Poria, Radix Angelicae Sinensis 10 parts, the Radix Paeoniae Alba 30 parts, 10 parts, Semen Persicae, Radix Et Rhizoma Rhei 10 parts, Herba Leonuri 30 parts, Rhizoma Cyperi 20 parts, Semen Coicis 30 parts, Spica Prunellae 30 parts, Radix Scrophulariae 12 parts, Os Draconis 15 parts, Concha Ostreae 30 parts, Semen Citri Reticulatae 15 parts, Semen Litchi 15 parts, Semen Vaccariae 6 parts, 6 parts, Radix Glycyrrhizae, Fructus Gardeniae (parched) 10 parts, Squama Manis 2 parts.
In above-mentioned formula, the source of various medical material and function cure mainly as follows:
Radix Bupleuri [source] this product is the dry root of umbelliferae bupleurum Bupleurum chinense DC. or Radix Bupeuri Scorzonerfolii. Bupleurum scorzonerifolium Willd..[nature and flavor] are bitter, are slightly cold.[return through] returns liver, gallbladder meridian.[function cures mainly] reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
The Rhizoma Atractylodis Macrocephalae [source] this product is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..[nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Poria [source] this product is the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.[nature and flavor] are sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix Angelicae Sinensis [source] this product is the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
The Radix Paeoniae Alba [source] this product is the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..[nature and flavor] are bitter, sour, are slightly cold.[return through] returns liver, spleen channel.The pain relieving of [function cures mainly] suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Semen Persicae [source] this product is the dry mature seed of rosaceous plant Fructus Persicae Prunus persica (L.) Batsch or Prunus davidiana Prunus davidiana (Carr.) Franch..[nature and flavor] bitter, sweet, flat.[return through] GUIXIN, liver, large intestine channel.[function cures mainly] blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Radix Et Rhizoma Rhei [source] this product is polygonum rheum palmatum Rheum palmatum L., Rheum tanguticum Rheum tanguticum Maxim.ex Balf。Or Rheum officinale Rheum officinale Baill.Dry root and rhizome.[nature and flavor] are bitter, cold.[return through] returns spleen, stomach, large intestine, liver, pericardium channel.[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.
Herba Leonuri [source] this product is the fresh or dry aerial parts of labiate Herba Leonuri Leonurus japonicus Houtt..[nature and flavor] are bitter, pungent, are slightly cold.[return through] returns liver, pericardium channel.[function cures mainly] promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.
Rhizoma Cyperi [source] this product is the dry rhizome of sedge dried tuber Cyperus rotundus L..[nature and flavor] pungent, micro-hardship, micro-sweet, flat.[return through] returns liver, spleen, tri-jiao channel.[function cures mainly] promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Semen Coicis [source] this product is the dry mature kernal of grass Semen Coicis Coix lacryma-jobi L. var. ma-yuen (Roman.) Stapf.[nature and flavor] are sweet, light, cool.[return through] returns spleen, stomach, lung meridian.[function cures mainly] spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, row is dense in heat clearing away.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.
Spica Prunellae [source] this product is the dry fruit ear of labiate Spica Prunellae Prunella vulgaris L..[nature and flavor] are pungent, bitter, cold.[return through] returns liver, gallbladder meridian.[function cures mainly] relieves inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Radix Scrophulariae [source] this product is the dry root of goatweed Radix Scrophulariae Scrophularia ningpoensis Hemsl..[nature and flavor] are sweet, bitter, salty, are slightly cold.[return through] returns lung, stomach, kidney channel.[function cures mainly] removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Os Draconis [source] for ancient times mammal as if the Skeletal Fossils of class, rhinoceros class, Hippocampal cortex etc.[nature and flavor] are sweet, puckery, flat.[return through] heart, liver, kidney, large intestine channel.[function cures mainly] is calm, arresting sweating arresting seminal emission, promoting tissue regeneration and ulcer healing.For neurasthenia, cardiopalmus, insomnia, dreaminess, spontaneous perspiration, night sweat, seminal emission, the enuresis, metrorrhagia, leukorrhagia; External control skin infection for a long time burst do not hold back.
Concha Ostreae [source] this product is the shell of Ostreidae animal long Concha Ostreae Ostrea gigas Thunberg, Dalian Bay Concha Ostreae Ostrea talienwhanensis Crosse or Crassostrea rivularis Ostrea rivularis Gould.[nature and flavor] are salty, are slightly cold.[return through] returns liver, gallbladder, kidney channel.[function cures mainly] tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.For spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.
Semen Citri Reticulatae [source] this product is the dry mature seed of rutaceae orange Citrus reticulata Blanco and variety thereof.[nature and flavor] are bitter, flat.[return through] returns liver, kidney channel.[function cures mainly] regulates the flow of vital energy, eliminating stagnation, pain relieving.For inguinal hernia, painful and swollen testis, acute mastitis swells and ache.
Semen Litchi [source] this product is the dry mature seed of sapindaceous plant Fructus Litchi Litchi chinensis Sonn..[nature and flavor] sweet, micro-hardship, temperature.[return through] returns liver, kidney channel.[function cures mainly] promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.For colic of cold type stomachache, painful and swollen testis.
Semen Vaccariae [source] this product is pinkwort Vaccaria segetalis Vaccariasegetalis(neck) dry seed of Garcker.[nature and flavor] are bitter, flat.[return through] returns liver, stomach warp.[function cures mainly] has promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain, expedites the emergence of the function of stimulating milk secretion.Cure mainly blood stasis amenorrhea, dysmenorrhea, difficult labour; Lack of lactation after delivery, acute mastitis swells and ache; Pyretic stranguria, stranguria with blood, stranguria caused by urinary stone.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Fructus Gardeniae (parched) [source] this product is the dry mature fruit of Maguireothamnus speciosus Fructus Gardeniae Gardenia jasminoides Ellis.Fructus Gardeniae (parched): get clean Fructus Gardeniae, fries to yellowish-brown according to frying method.[nature and flavor] are bitter, cold.[return through] GUIXIN, lung, tri-jiao channel.[function cures mainly] fruit: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
Squama Manis [source] this product is the scute of Manidae animal Squama Manis Manis pentadactyla Linnaeus.[nature and flavor] are salty, are slightly cold.[return through] returns liver, stomach warp.[function cures mainly] stimulates the menstrual flow stimulating milk secretion, detumescence and apocenosis, expel wind to dredge collateral.For Jing Bi WEIJIA, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.
The traditional Chinese medical science is thought, the growth of breast, growth, wither be that the generation of nodules of the breast and liver have very large relation, blood stored in the liver by the domination of the essence of five ZANG-organs and six FU-organs gas, dredge regulating QI machine, the thin malfunction that converges of liver, depression of liver-QI, impact punching is appointed, the regulatory function of QI and blood, newborn network inanition is lost support, the evil visitor of impression, blood stasis, expectorant block painful abdominal mass are tied, and are form nodules of the breast." wood does not strongly fragrantly reach, breast knot addiction ", depressed impairing the liver, worry impairing spleen, long-pendingly wants at the heart, think unappreciated person, cause meridians disease puckery, coalescent nucleation.Irritability stasis, the smooth hyperamization addiction of QI-blood circulation, in meridians, makes spleen transport mistake department, and body fluid can not normal defeated cloth and condense into expectorant, ties mutually form syndrome of stagnation of liver qi and blood stasis type nodules of the breast disease with blood stasis.The Chinese medicine obtained according to formula of the present invention has dispersing the stagnated live-QI to relieve the stagnation of QI, eliminate stagnation and dissolve phlegm, hard masses softening and resolving and has effect of regulating thoroughfare and controlling vessel, effectively can control effect nodules of the breast sick, and obviously can improve the simultaneous phenomenon of patient, without obvious side effect, to the sick safety for the treatment of nodules of the breast, effectively.Over 3 years, by showing the use of 82 routine patients, effective percentage reaches 90.2%, no longer recurs more.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor have collected the sick out-patients of 148 routine syndrome of stagnation of liver qi and blood stasis type nodules of the breast altogether between in June ,-2012 in June, 2009, age 18-50 year, the state of an illness 3 months-5 years.Be divided at random: treatment group 82 example, matched group 66 example.The data there was no significant differences such as two groups of ages, have comparability.
2, test method
The oral decoction for removing blood stasis of 2.1 matched group, takes to specifications.20 days courses for the treatment of.
The oral the present invention of 2.2 treatment group is according to the obtained capsule of specific embodiment 1, and early, evening is each once, one after each meal, 20 days courses for the treatment of.Effective case follows up a case by regular visits to one month, and menstrual phase is withdrawn.Treatments period two groups all must not use hormone, pain relieving class Western medicine and similar Chinese medicine.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterions of therapeutical effect:
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, experimental check improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Group |
n |
Recovery from illness |
Take a turn for the better |
Invalid |
Total effective rate (%) |
Treatment group |
82 |
22 |
52 |
7 |
90.2% |
Matched group |
66 |
9 |
22 |
35 |
46.9% |
As can be seen here, the medicine that the present invention obtains can safe and effective treatment syndrome of stagnation of liver qi and blood stasis type nodules of the breast disease.
Detailed description of the invention
In order to Comprehension and Implementation the present invention better, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take Radix Bupleuri 10 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, 30 grams, Poria, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 30 grams, 10 grams, Semen Persicae, Radix Et Rhizoma Rhei 10 grams, Herba Leonuri 30 grams, Rhizoma Cyperi 20 grams, Semen Coicis 30 grams, Spica Prunellae 30 grams, Radix Scrophulariae 12 grams, Os Draconis 15 grams, Concha Ostreae 30 grams, Semen Citri Reticulatae 15 grams, Semen Litchi 15 grams, Semen Vaccariae 6 grams, 6 grams, Radix Glycyrrhizae, Fructus Gardeniae (parched) 10 grams, Squama Manis 2 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of syndrome of stagnation of liver qi and blood stasis type nodules of the breast sick, oral, every bu early, late secondary takes.
Specific embodiment 2
Take Radix Bupleuri 10 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, 30 grams, Poria, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 30 grams, 10 grams, Semen Persicae, Radix Et Rhizoma Rhei 10 grams, Herba Leonuri 30 grams, Rhizoma Cyperi 20 grams, Semen Coicis 30 grams, Spica Prunellae 30 grams, Radix Scrophulariae 12 grams, Os Draconis 15 grams, Concha Ostreae 30 grams, Semen Citri Reticulatae 15 grams, Semen Litchi 15 grams, Semen Vaccariae 6 grams, 6 grams, Radix Glycyrrhizae, Fructus Gardeniae (parched) 10 grams, Squama Manis 2 grams, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's 1 day consumption.
Be used for the treatment of syndrome of stagnation of liver qi and blood stasis type nodules of the breast sick, oral, every bu early, late secondary takes.
Specific embodiment 3
Take Radix Bupleuri 10 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, 30 grams, Poria, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 30 grams, 10 grams, Semen Persicae, Radix Et Rhizoma Rhei 10 grams, Herba Leonuri 30 grams, Rhizoma Cyperi 20 grams, Semen Coicis 30 grams, Spica Prunellae 30 grams, Radix Scrophulariae 12 grams, Os Draconis 15 grams, Concha Ostreae 30 grams, Semen Citri Reticulatae 15 grams, Semen Litchi 15 grams, Semen Vaccariae 6 grams, 6 grams, Radix Glycyrrhizae, Fructus Gardeniae (parched) 10 grams, Squama Manis 2 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, must meet the granule of adult normal's 1 day consumption.
Be used for the treatment of syndrome of stagnation of liver qi and blood stasis type nodules of the breast sick, oral, every bu early, late secondary takes.