Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of qi depression to blood stasis pattern of syndrome note of the ancient Chinese abdominal mass disease, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing qi depression to blood stasis pattern of syndrome note of the ancient Chinese abdominal mass disease.
For achieving the above object, the present invention by the following technical solutions:
Treat a Chinese medicine for qi depression to blood stasis pattern of syndrome mass in the abdomen disease, it is characterized in that being prepared from by the medical material of following weight proportion:
Radix Bupleuri 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 20 parts, Poria, Radix Angelicae Sinensis 10 parts, Radix Paeoniae Rubra 15 parts, Cortex Moutan 10 parts, Rhizoma Cyperi 20 parts, Concha Ostreae 30 parts, Spica Prunellae 30 parts, Semen Coicis 30 parts, vinegar Squama Manis 2 parts, Semen Vaccariae (parched) 6 parts, Fructus Crataegi 30 parts, Radix Et Rhizoma Rhei 10 parts, 10 parts, Semen Persicae, 6 parts, Nidus Vespae, Ramulus Cinnamomi 20 parts, 6 parts, Radix Glycyrrhizae, Herba Leonuri 30 parts, Arillus Longan 10 parts, 20 parts, Radix Rubiae.
In formula of the present invention, the source of various medical material and function cure mainly as follows:
Radix Bupleuri [source] this product is the dry root of umbelliferae bupleurum Bupleurum chinense DC. or Radix Bupeuri Scorzonerfolii. Bupleurum scorzonerifolium Willd..[nature and flavor] are bitter, are slightly cold.[return through] returns liver, gallbladder meridian.[function cures mainly] reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
The Rhizoma Atractylodis Macrocephalae [source] this product is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..[nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Poria [source] this product is the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.[nature and flavor] are sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix Angelicae Sinensis [source] this product is the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.[nature and flavor] sweet, acrid, warm.[return through] returns liver, the heart, spleen channel.
[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Radix Paeoniae Rubra [source] this product is the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall. or river Radix Paeoniae Rubra Paeonia veitchii Lynch.[nature and flavor] are bitter, are slightly cold.[return through] returns Liver Channel.[function cures mainly] clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection.
Cortex Moutan [source] this product is the dry root bark of ranunculaceae peony Paeonia suffruticosa Andr..[nature and flavor] are bitter, pungent, are slightly cold.[return through] GUIXIN, liver, kidney channel.[function cures mainly] clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Rhizoma Cyperi [source] this product is the dry rhizome of sedge dried tuber Cyperus rotundus L..[nature and flavor] pungent, micro-hardship, micro-sweet, flat.[return through] returns liver, spleen, tri-jiao channel.
[function cures mainly] promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Concha Ostreae [source] this product is the shell of Ostreidae animal long Concha Ostreae Ostrea gigas Thunberg, Dalian Bay Concha Ostreae Ostrea talienwhanensis Crosse or Crassostrea rivularis Ostrea rivularis Gould.[nature and flavor] are salty, are slightly cold.[return through] returns liver, gallbladder, kidney channel.[function cures mainly] tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.
Spica Prunellae [source] this product is the dry fruit ear of labiate Spica Prunellae Prunella vulgaris L..[nature and flavor] are pungent, bitter, cold.[return through] returns liver, gallbladder meridian.[function cures mainly] relieves inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Semen Coicis [source] this product is the dry mature kernal of grass Semen Coicis Coix lacryma-jobi L. var. ma-yuen (Roman.) Stapf.[nature and flavor] are sweet, light, cool.
[return through] returns spleen, stomach, lung meridian.[function cures mainly] spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, row is dense in heat clearing away.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.
Vinegar Squama Manis [source] this product is the scute of Manidae animal Squama Manis Manis pentadactyla Linnaeus.Vinegar Squama Manis: get clean Squama Manis, size separately, is scalded to heaving by upper method, quench in vinegar, takes out, dry.Used time smashs to pieces.Every 100kg Squama Manis, uses vinegar 30kg.[nature and flavor] are salty, are slightly cold.[return through] returns liver, stomach warp.[function cures mainly] stimulates the menstrual flow stimulating milk secretion, detumescence and apocenosis, expel wind to dredge collateral.For Jing Bi WEIJIA, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.
The seed that Semen Vaccariae (parched) [source] is pinkwort Vaccaria segetalis.[nature and flavor] are bitter, flat.[return through] enters liver, stomach warp.[function cures mainly] promoting the circulation of blood is stimulated the menstrual flow, and expedites the emergence of stimulating milk secretion, detumescence sore.Control women's amenorrhea, galactostasis, difficult labour, stranguria with blood, carbuncle, incised wound is hemorrhage.
Fructus Crataegi [source] this product is the dry mature fruit of rosaceous plant Fructus Pyri Pashiae Crataegus pinnatifida Bge.var.major N.E.Br. or Fructus Crataegi Crataegus pinnatifida Bge..[nature and flavor] are sour, sweet, tepor.[return through] returns spleen, stomach, Liver Channel.[function cures mainly] promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.
Radix Et Rhizoma Rhei [source] this product is polygonum rheum palmatum Rheum palmatum L., Rheum tanguticum Rheum tanguticum Maxim.ex Balf。Or Rheum officinale Rheum officinale Baill.Dry root and rhizome.[nature and flavor] are bitter, cold.[return through] returns spleen, stomach, large intestine, liver, pericardium channel.[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.
Semen Persicae [source] this product is the dry mature seed of rosaceous plant Fructus Persicae Prunus persica (L.) Batsch or Prunus davidiana Prunus davidiana (Carr.) Franch..[nature and flavor] bitter, sweet, flat.[return through] GUIXIN, liver, large intestine channel.[function cures mainly] blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Nidus Vespae [source] this product is the nest of Vespidae insecticide fruit hornet Polistes olivaceous (DeGeer), Japanese long foot wasp Polistes japonicus Saussure or different abdomen wasp Parapolybia varia Fabricius.[nature and flavor] are sweet, flat.[return through] returns stomach warp.
[function cures mainly] dispels the wind, merit poison, parasite killing, pain relieving.For toothache due to dental caries, sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, fungal infection of hand and foot.
Ramulus Cinnamomi [source] this product is the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.[nature and flavor] acrid, sweet, warm.[return through] GUIXIN, lung, urinary bladder channel.[function cures mainly] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Herba Leonuri [source] this product is the fresh or dry aerial parts of labiate Herba Leonuri Leonurus japonicus Houtt..[nature and flavor] are bitter, pungent, are slightly cold.[return through] returns liver, pericardium channel.[function cures mainly] promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.
Arillus Longan [source] this product is the aril of Sapindaceae Euphoria plant Arillus Longan Dimocarpus longan Lour..[nature and flavor] are sweet, temperature.[return through] GUIXIN, spleen channel.[function cures mainly] invigorating the heart and spleen, nourishing blood to tranquillize the mind.For insufficiency of vital energy and blood, severe palpitation, forgetful insomnia, blood deficiency and yellow complexion.
Radix Rubiae [source] this product is the dry root and rhizome of Maguireothamnus speciosus Radix Rubiae Rubia cordifolia L..[nature and flavor] are bitter, cold.[return through] returns Liver Channel.[function cures mainly] removing heat from blood, hemostasis, blood stasis dispelling, stimulates the menstrual flow.For spitting blood, epistaxis, metrorrhagia, traumatic hemorrhage, amenorrhea stasis blocking, arthralgia, tumbling and swelling.
The pathogenesis of qi depression to blood stasis pattern of syndrome mass in the abdomen disease is many because of zang-fu disharmony, and QI and blood blocks, and knot in blood stasis, gas gathers for abdominal mass, and blood stasis is Disorder.Clinically, the symptom of qi depression to blood stasis pattern of syndrome mass in the abdomen patient is generally in born of the same parents lumps, and long-pending block is not hard, push away movable, or long-pending block is hard, fixes and does not move; Inferior belly gas pain or distension, or menoxenia, menstrual period inferior belly gas pain, tenderness, external genitalia and anus falling inflation is for just, and through dark purplish blood with clots, block unstings and subtracts, mammary swelling uncomfortable in chest; Dim complexion, the weary profit of skin; Purplish tongue secretly has petechia, white and thin fur, stringy pulse or puckery.The present invention adopts suitable medical material and proportioning thereof, obtained Chinese medicine has effect of circulation of qi promoting intestinal stasis relieving, blood circulation promoting and dispersing pathogen accumulation, blood-activating analgetic, removing blood stasis to resolve lump, over 5 years, by showing the use of 100 patients, the effective percentage being used for the treatment of qi depression to blood stasis pattern of syndrome mass in the abdomen disease reaches 90%.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor have collected the sick out-patients of 179 routine qi depression to blood stasis pattern of syndrome mass in the abdomen altogether between in June ,-2013 in June, 2008, age 25-45 year; The state of an illness 3 months-2 years; Patient history: often have the medical history such as " menopathy ", infertility, leukorrheal diseases, psychic trauma history; Patient symptom: hypogastric region enclosed mass, or swollen or pain or full, with irregular menstruation, dysmenorrhea, and leukorrhagia exception etc.; Ultrasonic diagnosis: ovary chocolate cyst diameter, hysteromyoma≤5cm; Tumor markers: CA125≤200U/ml.Be divided at random: treatment group 100 example, matched group 79 example.The data there was no significant differences such as two groups of ages, have comparability.
2, test method
2.1 matched group oral Fructus Citri tangerinae litchi Sanjie Pill, takes to specifications.The course for the treatment of 3 menstrual cycle.
The oral the present invention of 2.2 treatment group according to the obtained capsule of specific embodiment 1, early, middle and late each once, one after each meal, the course for the treatment of 3 menstrual cycle.Effective case follows up a case by regular visits to two months, and menstrual phase is withdrawn.Treatments period two groups all must not use hormone, pain relieving class Western medicine and similar Chinese medicine.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterions of therapeutical effect:
Recovery from illness: symptom (comprising blood stasis syndrome) all disappears, ovary chocolate cyst is through gynecologial examination, and the local such as ultrasound diagnosis pelvic lump sign disappears substantially.
Effective: symptom (comprising blood stasis syndrome) disappears substantially, ovary chocolate cyst is through gynecologial examination, and B ultrasonic inspection Endometrial adenocarcinoma three footpath sum reduces more than 1/2, and clinical symptoms partly or entirely disappears.
Effective: symptom alleviates, ovary chocolate cyst is through gynecologial examination, and ultrasound diagnosis cyst three footpath sum reduces more than 1/3, clinical symptoms partial disappearance or alleviate.
Invalid: more than a course for the treatment of of taking medicine continuously, ultrasound diagnosis cyst three footpath sum is without change or reduce less than 1cm, and subjective symptoms alleviates or without change.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Group |
n |
Recovery from illness |
Effective |
Effectively |
Invalid |
Total effective rate (%) |
Treatment group |
100 |
31 |
27 |
32 |
10 |
90% |
Matched group |
79 |
11 |
14 |
19 |
35 |
55.7% |
As can be seen here, the medicine that the present invention obtains can safe and effective treatment qi depression to blood stasis pattern of syndrome mass in the abdomen disease.
Detailed description of the invention
In order to Comprehension and Implementation the present invention better, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take Radix Bupleuri 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, 20 grams, Poria, Radix Angelicae Sinensis 10 grams, Radix Paeoniae Rubra 15 grams, Cortex Moutan 10 grams, Rhizoma Cyperi 20 grams, Concha Ostreae 30 grams, Spica Prunellae 30 grams, Semen Coicis 30 grams, vinegar Squama Manis 2 grams, Semen Vaccariae (parched) 6 grams, Fructus Crataegi 30 grams, Radix Et Rhizoma Rhei 10 grams, 10 grams, Semen Persicae, 6 grams, Nidus Vespae, Ramulus Cinnamomi 20 grams, 6 grams, Radix Glycyrrhizae, Herba Leonuri 30 grams, Arillus Longan 10 grams, 20 grams, Radix Rubiae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of qi depression to blood stasis pattern of syndrome mass in the abdomen sick, oral, every bu is taken for early, middle and late three times.
Specific embodiment 2
Take Radix Bupleuri 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, 20 grams, Poria, Radix Angelicae Sinensis 10 grams, Radix Paeoniae Rubra 15 grams, Cortex Moutan 10 grams, Rhizoma Cyperi 20 grams, Concha Ostreae 30 grams, Spica Prunellae 30 grams, Semen Coicis 30 grams, vinegar Squama Manis 2 grams, Semen Vaccariae (parched) 6 grams, Fructus Crataegi 30 grams, Radix Et Rhizoma Rhei 10 grams, 10 grams, Semen Persicae, 6 grams, Nidus Vespae, Ramulus Cinnamomi 20 grams, 6 grams, Radix Glycyrrhizae, Herba Leonuri 30 grams, Arillus Longan 10 grams, 20 grams, Radix Rubiae, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's 1 day consumption.
Be used for the treatment of qi depression to blood stasis pattern of syndrome mass in the abdomen sick, oral, every bu is taken for early, middle and late three times.
Specific embodiment 3
Take Radix Bupleuri 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, 20 grams, Poria, Radix Angelicae Sinensis 10 grams, Radix Paeoniae Rubra 15 grams, Cortex Moutan 10 grams, Rhizoma Cyperi 20 grams, Concha Ostreae 30 grams, Spica Prunellae 30 grams, Semen Coicis 30 grams, vinegar Squama Manis 2 grams, Semen Vaccariae (parched) 6 grams, Fructus Crataegi 30 grams, Radix Et Rhizoma Rhei 10 grams, 10 grams, Semen Persicae, 6 grams, Nidus Vespae, Ramulus Cinnamomi 20 grams, 6 grams, Radix Glycyrrhizae, Herba Leonuri 30 grams, Arillus Longan 10 grams, 20 grams, Radix Rubiae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, must meet the granule of adult normal's 1 day consumption.
Be used for the treatment of qi depression to blood stasis pattern of syndrome mass in the abdomen sick, oral, every bu is taken for early, middle and late three times.