CN103520571B - Traditional Chinese medicine for treating qi stagnation and blood stasis syndrome type abdominal mass - Google Patents

Abstract

The invention discloses a traditional Chinese medicine for treating qi stagnation and blood stasis syndrome type abdominal mass, which is characterized by being prepared from the following medicinal materials in parts by weight: 10 parts of radix bupleuri, 10 parts of bighead atractylodes rhizome, 20 parts of poria cocos, 10 parts of Chinese angelica, 15 parts of red paeony root, 10 parts of tree peony bark, 20 parts of rhizoma cyperi, 30 parts of oyster, 30 parts of selfheal, 30 parts of coix seed, 2 parts of vinegar-processed pangolin scales, 6 parts of fried cowherb seed, 30 parts of hawthorn, 10 parts of rheum officinale, 10 parts of peach kernel, 6 parts of honeycomb, 20 parts of cassia twig, 6 parts of liquorice, 30 parts of motherwort, 10 parts of longan pulp and 20 parts of madder. The traditional Chinese medicine has the effects of promoting qi circulation, removing stagnation, promoting blood circulation, removing stasis, relieving pain, breaking stasis and eliminating mass, and the use of 100 patients proves that the effective rate of treating qi stagnation and blood stasis syndrome type mass disease reaches 90% in 5 years.

Description

Traditional Chinese medicine for treating lump in the abdomen of Qi stagnation and blood stasis syndrome

technical field

The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine for treating lump in the abdomen of Qi stagnation and blood stasis syndrome.

Background technique

Gynecological lumps cover a variety of gynecological benign tumors, and there are many types of diseases, which are common and difficult diseases in gynecology. Women with lumps in the lower abdomen and abdomen, accompanied by abdominal distension, fullness, or vaginal bleeding, and pain in the lower abdomen, are collectively referred to as lumps in the abdomen. The disease mostly occurs in the lower Jiao. Generally, lumps are found hidden in the abdomen, which can be verified according to the shape, firm and unmovable, and pain with a fixed location is a symptom; Those who move are called lumps in the abdomen. This disease is usually caused by emotional depression, internal injury from diet, liver and spleen damage, visceral disharmony, and lack of righteousness over time, leading to qi stagnation, blood stasis, phlegm dampness, and damp heat. Usually, qi stagnation and blood stasis Syndrome-type lump in the abdomen accounted for a higher proportion. At present, the methods for the treatment of qi stagnation and blood stasis type lump in the abdomen include surgical treatment, western medicine treatment, acupuncture treatment, in vitro treatment and traditional Chinese medicine treatment. The cost of surgical treatment is high, and the patient is traumatized. Western medicine treatment, acupuncture treatment, in vitro treatment All treat the symptoms but not the disease, and the disclosed Chinese medicine that can be used for the treatment of qi stagnation and blood stasis syndrome type lump in the abdomen, though certain effect is arranged, the effect is not ideal, and there are defects such as low cure rate.

Contents of the invention

The invention aims to provide a traditional Chinese medicine for treating lump in the abdomen of the syndrome of qi stagnation and blood stasis, through selecting appropriate medicinal materials and their proportions, to achieve the purpose of safely and effectively curing the lump in the abdomen of the syndrome of qi stagnation and blood stasis.

To achieve the above object, the present invention adopts the following technical solutions:

A traditional Chinese medicine for treating lump in the abdomen of qi stagnation and blood stasis syndrome, characterized in that it is prepared from the following medicinal materials in weight ratio:

10 parts of bupleurum, 10 parts of Atractylodes macrocephala, 20 parts of poria, 10 parts of angelica, 15 parts of red peony, 10 parts of Moutan bark, 20 parts of Cyperus cyperi, 30 parts of oyster, 30 parts of Prunella vulgaris, 30 parts of coix seed, 2 parts of vinegar pangolin , 6 servings of fried blanc berry, 30 servings of hawthorn, 10 servings of rhubarb, 10 servings of peach kernel, 6 servings of hive, 20 servings of cinnamon sticks, 6 servings of licorice, 30 servings of motherwort, 10 servings of longan meat, and 20 servings of madder.

The source and function of various medicinal materials in the formula of the present invention are as follows:

Bupleurum [source] This product is the dried root of Bupleurum chinense DC. or Bupleurum scorzonerifolium Willd. of Umbelliferae. [nature and flavor] bitter, slightly cold. [return through] returns liver, gallbladder meridian. [Functions and Indications] Reconcile the exterior and interior, soothe the liver, and promote yang. For common cold and fever, alternating cold and heat, distending pain in the chest and hypochondrium, irregular menstruation, prolapse of the genitals, and prolapse of the anus.

Atractylodes [source] This product is the dry rhizome of Atractylodes macrocephala Koidz. [nature and flavor] bitter, sweet, warm. [return through] returns spleen, stomach meridian. [Functions and Indications] Invigorate the spleen and replenish qi, dry dampness and promote diuresis, stop sweating, and prevent miscarriage. For insufficiency of the spleen, lack of food, abdominal distension and diarrhea, dizziness and palpitation due to phlegm and retention, edema, spontaneous sweating, restless fetal movement.

Poria [source] This product is the dried sclerotia of Polyporaceae Poria cocos (Schw.) Wolf. [nature and flavor] sweet, light, flat. [return through] return to the heart, lung, spleen, kidney channel. [Functions and Indications] Diuretic and dampness expelling, invigorating the spleen and calming the heart. For edema, oliguria, dizziness and palpitation due to phlegm and retention, insufficiency of the spleen, lack of food, loose stool and diarrhea, restlessness, palpitation and insomnia.

Angelica [source] This product is the dried root of Angelica sinensis (Oliv.) Diels of Umbelliferae. [nature and flavor] sweet, pungent, warm. [return through] returns liver, heart, spleen channel.

[Functions and Indications] Enriching blood and promoting blood circulation, regulating menstruation and relieving pain, moistening intestines and laxative. For blood deficiency and yellow complexion, dizziness and palpitations, irregular menstruation, amenorrhea dysmenorrhea, abdominal pain due to deficiency and cold, constipation due to dryness of the intestine, rheumatic arthralgia, injury from falls, carbuncle sores.

Radix Paeoniae Rubra 【Source】 This product is the dried root of Paeonia lactiflora Pall. or Paeonia veitchii Lynch, a plant of Ranunculaceae. [nature and flavor] bitter, slightly cold. [return through] returns Liver Channel. [Functions and Indications] Clearing away heat and cooling blood, dissipating blood stasis and relieving pain. It is used for warming and poisoning spots, vomiting blood and epistaxis, conjunctival congestion and swelling pain, liver depression and hypochondriac pain, amenorrhea dysmenorrhea, abdominal pain in the abdomen, injury from falls, carbuncle sores.

Cortex Moutan 【Source】 This product is the dried root bark of Paeonia suffruticosa Andr. [nature and flavor] bitter, pungent, slightly cold. [return through] GUIXIN, liver, kidney channel. [Functions and Indications] Clearing heat and cooling blood, promoting blood circulation and removing blood stasis. It is used for warming and poisoning spots, vomiting blood and epistaxis, night heat and morning coolness, bone steam without sweat, amenorrhea dysmenorrhea, carbuncle sores, and pain caused by tumbling.

Rhizoma Cyperus 【Source】 This product is the dry rhizome of Cyperus rotundus L., a Cyperaceae plant. [nature and flavor] pungent, slightly bitter, slightly sweet, flat. [return through] returns liver, spleen, triple burner channel.

[Functions and Indications] Promoting qi and relieving depression, regulating menstruation and relieving pain. For liver depression and qi stagnation, distending pain in the chest, side of the body, and abdomen, dyspepsia, fullness in the chest and abdomen, abdominal pain due to cold colic, breast distending pain, irregular menstruation, amenorrhea dysmenorrhea.

Oyster [source] This product is the shell of Ostrea gigas Thunberg, Ostrea talienwhanensis Crosse or Ostrea rivularis Gould. [nature and flavor] salty, slightly cold. [return through] returns liver, gallbladder, kidney channel. [Functions and Indications] Calms the nerves, subdues yang and nourishes yin, softens hard masses and relieves stagnation. For palpitation with fear and insomnia, dizziness and tinnitus, scrofula sputum nucleus, lump in the abdomen in the abdomen.

Prunella vulgaris [source] This product is the dried fruit ear of Prunella vulgaris L., a plant of Lamiaceae. [nature and flavor] pungent, bitter, cold. [return through] returns liver, gallbladder meridian. [Functions and Indications] Clear fire, improve eyesight, dissipate stagnation, reduce swelling. For conjunctival congestion and swelling pain, eye pearl night pain, headache and dizziness, scrofula, goiter, mastitis swelling and pain; goiter, lymph node tuberculosis, breast hyperplasia, hypertension.

Coix Seed [Source] This product is the dry mature seed kernel of Coix lacryma-jobi L. var. ma-yuen (Roman.) Stapf, a grass plant. [nature and flavor] sweet, light, cool.

[return through] returns spleen, stomach, lung meridian. [Functions and Indications] Invigorating the spleen and expelling dampness, eliminating numbness and stopping diarrhea, clearing away heat and relieving congestion. For edema, beriberi, dysuria, arthralgia dampness spasm, diarrhea due to spleen deficiency, pulmonary abscess, intestinal abscess; flat wart.

Vinegar Pangolin [Source] This product is the scales of the pangolin Manis pentadactyla Linnaeus, a dace carp. Vinegar goats: take clean pangolins, separate them by size, scald them until they bulge, quench them with vinegar, take them out, and dry them. Mash when used. For every 100kg of pangolins, use 30kg of vinegar. [nature and flavor] salty, slightly cold. [return through] returns liver, stomach warp. 【Functions and Indications】Stimulating the menstrual flow and lowering the milk, reducing swelling and draining pus, searching wind and dredging collaterals. For amenorrhea lump in the abdomen, milk barrier, carbuncle sore, joint arthralgia, numbness and spasm.

Fried Wangbuliuxing [source] is the seed of Caryophyllaceae plant barley. [nature and flavor] bitter, flat. [return through] enter liver, stomach warp. [Functions and Indications] Promoting blood circulation to stimulate menstruation, promoting milk production, reducing swelling and suppressing sores. Control women's amenorrhea, milk obstruction, dystocia, bloody stranguria, carbuncle, hemorrhage from golden sore.

Hawthorn [source] This product is the dry and mature fruit of Crataegus pinnatifida Bge.var.major N.E.Br. or Crataegus pinnatifida Bge. of Rosaceae. [nature and flavor] sour, sweet, slightly warm. [return through] returns spleen, stomach, liver channel. [Functions and Indications] Dispelling food and invigorating the stomach, promoting qi and dispelling blood stasis. For stagnation of meat, fullness in the epigastric cavity, diarrhea and abdominal pain, amenorrhea due to blood stasis, postpartum stasis, tingling pain in trusted subordinates, hernia pain; hyperlipidemia.

Rhubarb 【Source】 This product is Rheum palmatum L, a plant of the Polygonaceae family. , Rheum tanguticum Maxim. ex Balf. Or medicinal Rheum officinale Baill. dry roots and rhizomes. [nature and flavor] bitter, cold. [return through] returns spleen, stomach, large intestine, liver, pericardium channel. [Functions and Indications] Purging heat and dredging intestines, cooling blood and detoxifying, removing blood stasis and dredging menstrual flow. Used for excess heat and constipation, stagnant abdominal pain, dysentery, damp-heat jaundice, vomiting of blood heat, red eyes, swollen throat, abdominal pain in the intestine, carbuncle and furuncle, blood stasis, amenorrhea, bruises, external treatment of water and fire burns ; Upper gastrointestinal bleeding.

Peach Kernel [Source] This product is the dry mature seed of Prunus persica (L.) Batsch or Prunus davidiana (Carr.) Franch. [nature and flavor] bitter, sweet, flat. [return through] Guixin, liver, large intestine channel. [Functions and Indications] Promoting blood circulation and removing blood stasis, moistening intestines and laxative. For amenorrhea, dysmenorrhea, lump in the abdomen, injury from falling down, dryness of the intestine and constipation.

[Source] This product is the nest of Polistes olivaceous (DeGeer), Polistes japonicus Saussure, or Parapolybia varia Fabricius. [nature and flavor] sweet, flat. [return through] returns stomach meridian.

[Functions and Indications] Expelling wind, detoxification, killing parasites, relieving pain. For dental caries and toothache, sore swollen poison, mastitis, scrofula, stubborn ringworm of the skin, goosefoot.

Guizhi [source] This product is the dry twig of Cinnamomum cassia Presl, a plant of Lauraceae. [nature and flavor] pungent, sweet, warm. [return through] heart, lung, bladder channel. [Functions and Indications] Producing sweat and relieving muscles, warming meridians, helping yang to transform qi, calming and descending qi. For anemofrigid cold, cold pain in the abdomen, amenorrhea due to cold in blood, arthralgia, phlegm retention, edema, palpitation, running ton.

Licorice [source] This product is the dried root of Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L., a leguminous plant. [nature and flavor] sweet, flat. [return through] Guixin, lung, spleen, stomach meridian. [Functions and Indications] Invigorating the spleen and replenishing qi, clearing heat and detoxification, eliminating phlegm and relieving cough, relieving spasm and relieving pain, harmonizing various medicines. For weakness of the spleen and stomach, lassitude and weakness, palpitation and shortness of breath, cough with copious phlegm, epigastric abdomen, extremity convulsion acute pain, carbuncle sore tumefacting virus, alleviates drug toxicity, strong.

Motherwort 【Source】 This product is the fresh or dry aerial part of Motherwort Leonurus japonicus Houtt. [nature and flavor] bitter, pungent, slightly cold. [return through] returns liver, pericardium channel. 【Functions and Indications】Promoting blood circulation and regulating menstruation, promoting diuresis and reducing swelling. For irregular menstruation, dysmenorrhea, amenorrhea, lochia, edema and oliguria; acute nephritis edema.

Longan meat [source] This product is the aril of longan Dimocarpus longan Lour. [nature and flavor] sweet, warm. [return through] Guixin, spleen channel. [Functions and Indications] Tonify the heart and spleen, nourish blood and calm the nerves. For lack of Qi and blood, palpitations, forgetfulness, insomnia, blood deficiency and chlorosis.

Rubia [source] This product is the dry root and rhizome of Rubia cordifolia L., a Rubiaceae plant. [nature and flavor] bitter, cold. [return through] returns Liver Channel. [Functions and Indications] Cooling blood, stopping bleeding, dispelling blood stasis, stimulating menstrual flow. For vomiting blood, epistaxis, uterine bleeding, traumatic bleeding, amenorrhea stasis, joint arthralgia, tumbling swelling pain.

The pathogenesis of lump in the abdomen of Qi stagnation and blood stasis syndrome type is mostly due to the imbalance of viscera, stagnation of qi and blood, internal knot of blood stasis, accumulation of gas into lump in the abdomen, and blood stasis as symptoms. Clinically, the symptoms of patients with lump in the abdomen of Qi stagnation and blood stasis syndrome are usually agglomerated in the cells, which are not firm and can be pushed, or hard and fixed; lower abdominal pain or fullness, or menstrual cramps Irregularity, lower abdominal distension and pain during menstruation, refusal to press, bloating of the front and rear vagina, desire to defecate, dark purple menstrual blood with lumps, pain relief of lumps, chest tightness and breast swelling; dull complexion, lack of moist skin; dark purple tongue with petechiae, thin fur White, stringy or astringent pulse. The present invention adopts suitable medicinal materials and their proportions, and the prepared traditional Chinese medicine has the effects of promoting qi and guiding stagnation, promoting blood circulation and dispelling stagnation, dispelling blood stasis and relieving pain, and dispelling blood stasis and eliminating symptoms. In the past 5 years, the use of 100 patients showed that the use of The effective rate in the treatment of qi stagnation and blood stasis syndrome is as high as 90%.

Below in conjunction with clinical experiment data illustrate the beneficial effect of the present invention:

1. General Information

From June 2008 to June 2013, the inventor collected 179 outpatients with qi stagnation and blood stasis syndrome type lump in the abdomen, aged 25-45 years; the condition was 3 months to 2 years; the patient's medical history: often "menstrual disease", infertility, leukorrhea, history of mental trauma, etc.; patient symptoms: lower abdominal mass, or swelling, pain, or fullness, accompanied by abnormal menstruation, dysmenorrhea, and abnormal leukorrhea; ultrasound diagnosis: Ovarian chocolate cyst diameter, uterine fibroids ≤ 5cm; tumor markers: CA125 ≤ 200U/ml. Randomly divided into: a treatment group of 100 cases, a control group of 79 cases. There was no significant difference in age and other data between the two groups, and they were comparable.

2. Test method

2.1 The control group took Juli Sanjie pills orally and took them according to the instructions. The course of treatment is 3 menstrual cycles.

2.2 The treatment group took the capsules prepared according to the specific embodiment 1 of the present invention orally, once in the morning, noon and evening, after meals, and the course of treatment was 3 menstrual cycles. Effective cases were followed up for two months, and the drug was discontinued during the menstrual period. During the treatment period, both groups were not allowed to use hormones, analgesic western medicines and similar traditional Chinese medicines.

3. Efficacy criteria and treatment results

3.1 Curative effect standard:

Recovery: all symptoms (including blood stasis syndrome) disappeared, local signs such as ovarian chocolate cyst and pelvic mass basically disappeared after gynecological examination and B-ultrasound examination.

Significantly effective: symptoms (including blood stasis syndrome) basically disappeared, the sum of the three diameters of endometrioma cysts in ovarian chocolate-like cysts was reduced by more than 1/2 in B-ultrasound examination, and clinical symptoms disappeared partially or completely.

Effective: Symptoms are alleviated. Gynecological examination of ovarian chocolate-like cysts shows that the sum of the three diameters of the cysts in B-ultrasonic examination has shrunk by more than 1/3, and the clinical symptoms have partially disappeared or been alleviated.

Ineffective: continuous medication for more than one course of treatment, B-ultrasound examination of the sum of the three diameters of the cyst remains unchanged or less than 1cm in size, and subjective symptoms are relieved or unchanged.

3.2 See Table 1 for the statistical results of treatment.

Table 1 Comparison of curative effect between the two groups

group no get well markedly effective efficient invalid Total effective rate (%) therapy group 100 31 27 32 10 90% control group 79 11 14 19 35 55.7%

Thus it can be seen that the medicine prepared by the present invention can safely and effectively treat Qi stagnation and blood stasis syndrome type lump in the abdomen.

Detailed ways

In order to better understand and implement the present invention, the present invention will be further described below in conjunction with specific examples.

Specific embodiment 1

Weigh 10 grams of Bupleurum, 10 grams of Atractylodes macrocephala, 20 grams of Poria cocos, 10 grams of angelica, 15 grams of red peony root, 10 grams of Moutan bark, 20 grams of Cyperus cyperi, 30 grams of oyster, 30 grams of Prunella vulgaris, 30 grams of coix seed, vinegar pangolin 2 grams, 6 grams of stir-fried wangbulixing, 30 grams of hawthorn, 10 grams of rhubarb, 10 grams of peach kernels, 6 grams of honeycomb, 20 grams of cinnamon sticks, 6 grams of licorice, 30 grams of motherwort, 10 grams of longan meat, 20 grams of madder, plus Add 8 times the amount of water, decoct for 1.5 hours, filter; add 6 times the amount of water to the filter residue, decoct for 1 hour, filter; combine the filtrates, concentrate, dry, put into capsule shells, and obtain capsules that meet the daily dosage of normal adults.

It is used to treat lump in the abdomen of Qi stagnation and blood stasis syndrome type. It is taken orally and taken three times a day in the morning, noon and night.

Specific embodiment 2

Weigh 10 grams of Bupleurum, 10 grams of Atractylodes macrocephala, 20 grams of Poria cocos, 10 grams of angelica, 15 grams of red peony root, 10 grams of Moutan bark, 20 grams of Cyperus cyperi, 30 grams of oyster, 30 grams of Prunella vulgaris, 30 grams of coix seed, vinegar pangolin 2 grams, 6 grams of stir-fried wangbulixing, 30 grams of hawthorn, 10 grams of rhubarb, 10 grams of peach kernels, 6 grams of honeycomb, 20 grams of cinnamon sticks, 6 grams of licorice, 30 grams of motherwort, 10 grams of longan meat, 20 grams of madder, plus Add 10 times the amount of water, decoct for 2 hours, filter; add 8 times the amount of water to the filter residue, decoct for 1.5 hours, filter; combine the filtrates, concentrate, dry, and pack to obtain a powder that meets the daily dosage of a normal adult.

It is used to treat lump in the abdomen of Qi stagnation and blood stasis syndrome type. It is taken orally and taken three times a day in the morning, noon and night.

Specific embodiment 3

Weigh 10 grams of Bupleurum, 10 grams of Atractylodes macrocephala, 20 grams of Poria cocos, 10 grams of angelica, 15 grams of red peony root, 10 grams of Moutan bark, 20 grams of Cyperus cyperi, 30 grams of oyster, 30 grams of Prunella vulgaris, 30 grams of coix seed, vinegar pangolin 2 grams, 6 grams of stir-fried wangbulixing, 30 grams of hawthorn, 10 grams of rhubarb, 10 grams of peach kernels, 6 grams of honeycomb, 20 grams of cinnamon sticks, 6 grams of licorice, 30 grams of motherwort, 10 grams of longan meat, 20 grams of madder, plus 8 times the amount of water, decoct for 1.5 hours, filter; add 6 times the amount of water to the filter residue, decoct for 1 hour, filter; combine the filtrate, concentrate, dry, add appropriate amount of dextrin and flavoring agent, and granulate according to the conventional process in this field , packaging, that is, granules that meet the daily dosage of normal adults.

It is used to treat lump in the abdomen of Qi stagnation and blood stasis syndrome type. It is taken orally and taken three times a day in the morning, noon and night.

Claims (1)

1. treat a Chinese medicine for qi depression to blood stasis pattern of syndrome mass in the abdomen disease, it is characterized in that being prepared from by the medical material of following weight proportion: Radix Bupleuri 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 20 parts, Poria, Radix Angelicae Sinensis 10 parts, Radix Paeoniae Rubra 15 parts, Cortex Moutan 10 parts, Rhizoma Cyperi 20 parts, Concha Ostreae 30 parts, Spica Prunellae 30 parts, Semen Coicis 30 parts, vinegar Squama Manis 2 parts, Semen Vaccariae (parched) 6 parts, Fructus Crataegi 30 parts, Radix Et Rhizoma Rhei 10 parts, 10 parts, Semen Persicae, 6 parts, Nidus Vespae, Ramulus Cinnamomi 20 parts, 6 parts, Radix Glycyrrhizae, Herba Leonuri 30 parts, Arillus Longan 10 parts, 20 parts, Radix Rubiae.