Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of qi depression to blood stasis pattern of syndrome note of the ancient Chinese abdominal mass disease, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing qi depression to blood stasis pattern of syndrome note of the ancient Chinese abdominal mass disease.
For achieving the above object, the present invention by the following technical solutions:
Treat a Chinese medicine for qi depression to blood stasis pattern of syndrome mass in the abdomen disease, it is characterized in that being prepared from by the medical material of following weight proportion:
10 parts of Radix Bupleuri, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts, Poria, 10 parts of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Rubra, 10 parts of Cortex Moutans, 20 parts of Rhizoma Cyperis, 30 parts of Concha Ostreaes, 30 parts of Spica Prunellaes, 30 parts of Semen Coiciss, 2 parts of vinegar Squama Maniss, 6 parts of Semen Vaccariae (parched)s, 30 parts of Fructus Crataegis, 10 parts of Radix Et Rhizoma Rhei, 10 parts, Semen Persicae, 6 parts, Nidus Vespae, 20 parts of Ramulus Cinnamomi, 6 parts, Radix Glycyrrhizae, 30 parts of Herba Leonuris, 10 parts of Arillus Longans, 20 parts, Radix Rubiae.
In the present invention's formula, source and the function of various medical materials cure mainly as follows:
Radix Bupleuri [source] this product is the dry root of umbelliferae bupleurum Bupleurum chinense DC. or Radix Bupeuri Scorzonerfolii. Bupleurum scorzonerifolium Willd..[nature and flavor] hardship, is slightly cold.[return through] returns liver, gallbladder meridian.[function cures mainly] reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
The Rhizoma Atractylodis Macrocephalae [source] this product is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..[nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Poria [source] this product is the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.[nature and flavor] are sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix Angelicae Sinensis [source] this product is the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.[nature and flavor] sweet, acrid, warm.[return through] returns liver, the heart, spleen channel.
[function cures mainly] enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Radix Paeoniae Rubra [source] this product is the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall. or river Radix Paeoniae Rubra Paeonia veitchii Lynch.[nature and flavor] hardship, is slightly cold.[return through] returns Liver Channel.[function cures mainly] clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection.
Cortex Moutan [source] this product is the dry root bark of ranunculaceae peony Paeonia suffruticosa Andr..[nature and flavor] are bitter, pungent, are slightly cold.[return through] GUIXIN, liver, kidney channel.[function cures mainly] clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Rhizoma Cyperi [source] this product is the dry rhizome of sedge dried tuber Cyperus rotundus L..[nature and flavor] pungent, micro-hardship, micro-sweet, flat.[return through] returns liver, spleen, tri-jiao channel.
[function cures mainly] promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Concha Ostreae [source] this product is the shell of the long Concha Ostreae Ostrea of Ostreidae animal gigas Thunberg, Dalian Bay Concha Ostreae Ostrea talienwhanensis Crosse or Crassostrea rivularis Ostrea rivularis Gould.[nature and flavor] are salty, are slightly cold.[return through] returns liver, gallbladder, kidney channel.[function cures mainly] tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.The insomnia that is used for palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.
Spica Prunellae [source] this product is the dry fruit ear of labiate Spica Prunellae Prunella vulgaris L..[nature and flavor] are pungent, bitter, cold.[return through] returns liver, gallbladder meridian.[function cures mainly] relieves inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, and goiter, acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Semen Coicis [source] this product is the dry mature kernal of grass Semen Coicis Coix lacryma-jobi L. var. ma-yuen (Roman.) Stapf.[nature and flavor] are sweet, light, cool.
[return through] returns spleen, stomach, lung meridian.[function cures mainly] spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, row is dense in heat clearing away.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.
Vinegar Squama Manis [source] this product is the scute of Manidae animal Squama Manis Manis pentadactyla Linnaeus.Vinegar Squama Manis: get clean Squama Manis, size separately, is scalded to heaving by upper method, quench in vinegar takes out, dry.Used time smashs to pieces.Every 100kg Squama Manis, uses vinegar 30kg.[nature and flavor] are salty, are slightly cold.[return through] returns liver, stomach warp.[function cures mainly] stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral.For Jing Bi WEIJIA, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.
Semen Vaccariae (parched) [source] is the seed of pinkwort Vaccaria segetalis.[nature and flavor] hardship, flat.[return through] enters liver, stomach warp.[function cures mainly] promoting the circulation of blood is stimulated the menstrual flow, and expedites the emergence of stimulating milk secretion, detumescence sore.Control women's amenorrhea, galactostasis, difficult labour, stranguria with blood, carbuncle, incised wound is hemorrhage.
Fructus Crataegi [source] this product is the dry mature fruit of rosaceous plant Fructus Pyri Pashiae Crataegus pinnatifida Bge.var.major N.E.Br. or Fructus Crataegi Crataegus pinnatifida Bge..[nature and flavor] are sour, sweet, tepor.[return through] returns spleen, stomach, Liver Channel.[function cures mainly] promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.
Radix Et Rhizoma Rhei [source] this product is polygonum rheum palmatum Rheum palmatum L., Rheum tanguticum Rheum tanguticum Maxim.ex?Balf。Or Rheum officinale Rheum officinale Baill.Dry root and rhizome.[nature and flavor] hardship, cold.[return through] returns spleen, stomach, large intestine, liver, pericardium channel.[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.
Semen Persicae [source] this product is the dry mature seed of rosaceous plant Fructus Persicae Prunus persica (L.) Batsch or Prunus davidiana Prunus davidiana (Carr.) Franch..[nature and flavor] bitter, sweet, flat.[return through] GUIXIN, liver, large intestine channel.[function cures mainly] blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Nidus Vespae [source] this product is the nest of Vespidae insecticide fruit hornet Polistes olivaceous (DeGeer), the long foot wasp Polistes japonicus Saussure of Japan or different abdomen wasp Parapolybia varia Fabricius.[nature and flavor] are sweet, flat.[return through] returns stomach warp.
[function cures mainly] dispels the wind, merit poison, parasite killing, pain relieving.For toothache due to dental caries, sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, fungal infection of hand and foot.
Ramulus Cinnamomi [source] this product is the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.[nature and flavor] acrid, sweet, warm.[return through] GUIXIN, lung, urinary bladder channel.[function cures mainly] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Herba Leonuri [source] this product is the fresh or dry aerial parts of labiate Herba Leonuri Leonurus japonicus Houtt..[nature and flavor] are bitter, pungent, are slightly cold.[return through] returns liver, pericardium channel.[function cures mainly] promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.
Arillus Longan [source] this product is the aril of Sapindaceae Euphoria plant Arillus Longan Dimocarpus longan Lour..[nature and flavor] are sweet, temperature.[return through] GUIXIN, spleen channel.[function cures mainly] invigorating the heart and spleen, nourishing blood to tranquillize the mind.For insufficiency of vital energy and blood, severe palpitation, forgetful insomnia, blood deficiency and yellow complexion.
Radix Rubiae [source] this product is the dry root and rhizome of Maguireothamnus speciosus Radix Rubiae Rubia cordifolia L..[nature and flavor] hardship, cold.[return through] returns Liver Channel.[function cures mainly] removing heat from blood, hemostasis, blood stasis dispelling, stimulates the menstrual flow.For spitting blood, epistaxis, metrorrhagia, traumatic hemorrhage, amenorrhea stasis blocking, arthralgia, tumbling and swelling.
The pathogenesis of qi depression to blood stasis pattern of syndrome mass in the abdomen disease is many because of zang-fu disharmony, QI and blood retardance, and knot in blood stasis, gas gathers for abdominal mass, and blood stasis is Disorder.Clinically, qi depression to blood stasis pattern of syndrome mass in the abdomen patient's symptom is generally in born of the same parents lumps, and long-pending piece is not hard, pushes away movably, or long-pending piece is hard, does not fixingly move; Inferior belly gas pain or distension, or menoxenia, menstrual period inferior belly gas pain, tenderness, external genitalia and anus falling inflation is wanted just, through dark purplish blood with clots, piece unstings and subtracts, mammary swelling uncomfortable in chest; Dim complexion, the weary profit of skin; Purplish tongue secretly has petechia, white and thin fur, stringy pulse or puckery.The present invention adopts suitable medical material and proportioning thereof, prepared Chinese medicine has the effect of circulation of qi promoting intestinal stasis relieving, blood circulation promoting and dispersing pathogen accumulation, blood-activating analgetic, removing blood stasis to resolve lump, over 5 years, by 100 patients' use is shown, the effective percentage that is used for the treatment of qi depression to blood stasis pattern of syndrome mass in the abdomen disease reaches 90%.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Inventor in June, 2008-2013 has collected the sick out-patients of 179 routine qi depression to blood stasis pattern of syndrome mass in the abdomen altogether between year June, age 25-45 year; The state of an illness 3 months-2 years; Patient history: often have the medical histories such as " menopathy ", infertility, leukorrheal diseases, psychic trauma history; Patient symptom: hypogastric region enclosed mass, or swollen or pain or full, with irregular menstruation, dysmenorrhea, and leukorrhagia is abnormal etc.; Ultrasonic diagnosis: ovary chocolate cyst diameter, hysteromyoma≤5cm; Tumor markers: CA125≤200U/ml.Be divided at random: treatment group 100 examples, matched group 79 examples.The data there was no significant differences such as two groups of ages, have comparability.
2, test method
The oral Fructus Citri tangerinae litchi of 2.1 matched group Sanjie Pill, takes to specifications.The course for the treatment of 3 menstrual cycle.
The capsule that the oral the present invention of 2.2 treatment group makes according to specific embodiment 1, early, middle and late each once, one after each meal, the course for the treatment of 3 menstrual cycle.Effectively case is followed up a case by regular visits to two months, and menstrual phase is withdrawn.During treatment, two groups all must not be used hormone, pain relieving class Western medicine and similar Chinese medicine.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterions of therapeutical effect:
Recovery from illness: symptom (comprising blood stasis syndrome) all disappears, and ovary chocolate cyst is through gynecologial examination, and the local signs such as ultrasound diagnosis pelvic lump disappear substantially.
Effective: symptom (comprising blood stasis syndrome) disappears substantially, ovary chocolate cyst is through gynecologial examination, and B ultrasonic inspection inner membrance dystopy cyst three footpath sums are dwindled more than 1/2, and clinical symptoms partly or entirely disappears.
Effective: symptom alleviates, ovary chocolate cyst is through gynecologial examination, and ultrasound diagnosis cyst three footpath sums are dwindled more than 1/3, and clinical symptoms partly disappears or alleviates.
Invalid: take medicine continuously one more than the course for the treatment of, ultrasound diagnosis cyst three footpath sums are without changing or dwindling not enough 1cm, subjective symptoms alleviates or without change.
3.2 treatment statistical results are in Table 1.
Table 1 liang group curative effect comparison
Group |
n |
Recovery from illness |
Effective |
Effectively |
Invalid |
Total effective rate (%) |
Treatment group |
100 |
31 |
27 |
32 |
10 |
90% |
Matched group |
79 |
11 |
14 |
19 |
35 |
55.7% |
As can be seen here, the medicine that the present invention makes can safe and effective treatment qi depression to blood stasis pattern of syndrome mass in the abdomen disease.
The specific embodiment
For Comprehension and Implementation the present invention better, below in conjunction with specific embodiment, further illustrate the present invention.
Specific embodiment 1
Take 10 grams of Radix Bupleuri, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams, Poria, 10 grams of Radix Angelicae Sinensis, 15 grams of Radix Paeoniae Rubra, 10 grams of Cortex Moutans, 20 grams of Rhizoma Cyperis, 30 grams of Concha Ostreaes, 30 grams of Spica Prunellaes, 30 grams of Semen Coiciss, 2 grams of vinegar Squama Maniss, 6 grams of Semen Vaccariae (parched)s, 30 grams of Fructus Crataegis, 10 grams of Radix Et Rhizoma Rhei, 10 grams, Semen Persicae, 6 grams, Nidus Vespae, 20 grams of Ramulus Cinnamomi, 6 grams, Radix Glycyrrhizae, 30 grams of Herba Leonuris, 10 grams of Arillus Longans, 20 grams, Radix Rubiae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, must meet the capsule of 1 day consumption of normal adult.
Be used for the treatment of qi depression to blood stasis pattern of syndrome mass in the abdomen sick, oral, every bu is taken for early, middle and late three times.
Specific embodiment 2
Take 10 grams of Radix Bupleuri, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams, Poria, 10 grams of Radix Angelicae Sinensis, 15 grams of Radix Paeoniae Rubra, 10 grams of Cortex Moutans, 20 grams of Rhizoma Cyperis, 30 grams of Concha Ostreaes, 30 grams of Spica Prunellaes, 30 grams of Semen Coiciss, 2 grams of vinegar Squama Maniss, 6 grams of Semen Vaccariae (parched)s, 30 grams of Fructus Crataegis, 10 grams of Radix Et Rhizoma Rhei, 10 grams, Semen Persicae, 6 grams, Nidus Vespae, 20 grams of Ramulus Cinnamomi, 6 grams, Radix Glycyrrhizae, 30 grams of Herba Leonuris, 10 grams of Arillus Longans, 20 grams, Radix Rubiae, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, pack, must meet the powder of 1 day consumption of normal adult.
Be used for the treatment of qi depression to blood stasis pattern of syndrome mass in the abdomen sick, oral, every bu is taken for early, middle and late three times.
Specific embodiment 3
Take 10 grams of Radix Bupleuri, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams, Poria, 10 grams of Radix Angelicae Sinensis, 15 grams of Radix Paeoniae Rubra, 10 grams of Cortex Moutans, 20 grams of Rhizoma Cyperis, 30 grams of Concha Ostreaes, 30 grams of Spica Prunellaes, 30 grams of Semen Coiciss, 2 grams of vinegar Squama Maniss, 6 grams of Semen Vaccariae (parched)s, 30 grams of Fructus Crataegis, 10 grams of Radix Et Rhizoma Rhei, 10 grams, Semen Persicae, 6 grams, Nidus Vespae, 20 grams of Ramulus Cinnamomi, 6 grams, Radix Glycyrrhizae, 30 grams of Herba Leonuris, 10 grams of Arillus Longans, 20 grams, Radix Rubiae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, and according to this area common process, granulate, pack, must meet the granule of 1 day consumption of normal adult.
Be used for the treatment of qi depression to blood stasis pattern of syndrome mass in the abdomen sick, oral, every bu is taken for early, middle and late three times.