CN103550608B - Traditional Chinese medicine for treating liver-stagnation and spleen-deficiency syndrome type hypomenorrhea - Google Patents
Traditional Chinese medicine for treating liver-stagnation and spleen-deficiency syndrome type hypomenorrhea Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating liver-stagnation and spleen-deficiency syndrome type hypomenorrhea. The traditional Chinese medicine is characterized by being prepared from the following medicinal materials in parts by weight: 10 parts of radix bupleuri, 10 parts of bighead atractylodes rhizome, 30 parts of poria cocos, 12 parts of Chinese angelica, 30 parts of radix paeoniae alba, 10 parts of cortex moutan, 10 parts of gardenia, 15 parts of fossil fragments, 30 parts of oyster, 15 parts of dried tangerine, 6 parts of radix sileris, 20 parts of semen coicis, 30 pars of motherwort, 20 parts of rhizoma cyperi, 30 parts of dogwood, 20 parts of cortex albiziae, 10 parts of polygala, 30 parts of zizyphus jujube kernel and 6 parts of licorice root. The traditional Chinese medicine has the advantages that the appropriate medicinal materials and the appropriate proportions are adopted, and the various medicinal materials are matched with one another and are synergistic, and the prepared traditional Chinese medicine has the effects of tonifying spleen and stomach, nourishing qi and blood, strengthening spleen and soothing liver and can be used for effectively treating the liver-stagnation and spleen-deficiency syndrome type hypomenorrhea. For three years, the using results of 100 patients prove that the effective rate of the traditional Chinese medicine reaches 92%.
Description
Technical field
The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine being used for the treatment of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea disease.
Background technology
Under normal circumstances, we are normal menstrual cycle, through measuring obvious minimizing, even drop is namely clean, or shortening menstrual period less than two days, also lacking person, be referred to as " hypomenorrhea " through amount.Also known as " a small amount of menses and menstruating unsmoothly ", " very few through measuring ", " through row pettiness ".It is generally acknowledged that hypomenorrhea is in 30 milliliters, is hypomenorrhea.The main pathogenesis of primary disease is deficiency of YIN-blood, and the sea of blood is comparatively hollow, and intrauterine material loses few, so few through row amount.The reason of hypomenorrhea is caused to have multiple, because the hypomenorrhea caused by stagnation of liver-QI with deficiency of the spleen is one wherein.At present, the method for the treatment of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea disease has Western medicine therapy, and also have herbal treatment, herbal treatment both can take stopgap measures, and also can effect a permanent cure, clinical practice is more.And at present, still do not have a kind of specially for the Chinese patent medicine of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine being used for the treatment of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea disease, by adopting suitable medical material and proportioning thereof, reaches the object for the treatment of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea disease safely and effectively.
The technical scheme adopted for realizing above-mentioned purpose of the present invention is: a kind of Chinese medicine for the treatment of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea disease, it is characterized in that being made up of the medical material of following weight proportion: Radix Bupleuri 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 30 parts, Poria, Radix Angelicae Sinensis 12 parts, the Radix Paeoniae Alba 30 parts, Cortex Moutan 10 parts, Fructus Gardeniae 10 parts, Os Draconis 15 parts, Concha Ostreae 30 parts, Pericarpium Citri Reticulatae 15 parts, Radix Saposhnikoviae 6 parts, Semen Coicis 20 parts, Herba Leonuri 30 parts, Rhizoma Cyperi 20 parts, Fructus Corni 30 parts, Cortex Albiziae 20 parts, Radix Polygalae 10 parts, Semen Ziziphi Spinosae 30 parts, 6 parts, Radix Glycyrrhizae.
The source of the medical material adopted in formula of the present invention and function cure mainly as follows:
Radix Bupleuri [source] is the dry root of umbelliferae bupleurum Bupleurum chinense DC. or Radix Bupeuri Scorzonerfolii. Bupleurum scorzonerifolium Willd..[nature and flavor] bitter, be slightly cold.[return through] enters liver, gallbladder meridian.[function cures mainly] has that expelling pathogenic factors from the exterior expels the heat-evil, effect of dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy, Compendium of Material Medica claims it to have, and Zhi Yangre sink, the burnt envelope of suppressing the hyperactive liver gallbladder three fire and the disease such as headache, dizzy, married woman's invasion of the blood-chamber by heat, irregular menstruation mutually, Radix Bupleuri is as clinical conventional Chinese medicine, clinical Chang Peiwu application, summing up it has thin strongly fragrant, the lucid yang sending up, merit that is evil, heat clearing away of faling apart.
The Rhizoma Atractylodis Macrocephalae [source] is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..[nature and flavor] nature and flavor are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For controlling deficiency-weakness of spleen-QI, anorexia and loose stool, phlegm retention edema, exterior deficiency spontaneous perspiration, frequent fetal movement.
Poria [source] is the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.[nature and flavor] nature and flavor are sweet, light, flat.[return through] GUIXIN, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.For controlling dysuria; Edema distension; Phlegm retention cough with dyspnea; Vomiting; Insufficiency of the spleen lack of appetite; Have loose bowels; Palpitation and restlessness; Insomnia forgetfulness; Seminal emission nebulousurine.
Radix Angelicae Sinensis [source] this product is the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.[nature and flavor] sweet, acrid, warm.[return through] returns liver, the heart, spleen channel.
[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
The Radix Paeoniae Alba [source] this product is the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..[nature and flavor] are bitter, sour, are slightly cold.[return through] returns liver, spleen channel.The pain relieving of [function cures mainly] suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Cortex Moutan [source] this product is the dry root bark of ranunculaceae peony Paeonia suffruticosa Andr..[nature and flavor] are bitter, pungent, are slightly cold.[return through] GUIXIN, liver, kidney channel.[function cures mainly] clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Fructus Gardeniae [source] this product is the dry mature fruit of Maguireothamnus speciosus Fructus Gardeniae Gardenia jasminoides Ellis.[nature and flavor] are bitter, cold.[return through] GUIXIN, lung, tri-jiao channel.[function cures mainly] fruit: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
Os Draconis [source] for ancient times mammal as if the fossil of skeleton of class, rhinoceros class, Hippocampal cortex etc.[nature and flavor] are sweet puckery; Flat; Nontoxic.[return through] enters heart channel, Liver Channel, kidney channel, large intestine channel.[function cures mainly] tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.
Concha Ostreae [source] this product is the shell of Ostreidae animal long Concha Ostreae Ostrea gigas Thunberg, Dalian Bay Concha Ostreae Ostrea talienwhanensis Crosse or Crassostrea rivularis Ostrea rivularis Gould.[nature and flavor] are salty, are slightly cold.[return through] returns liver, gallbladder, kidney channel.[function cures mainly] tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.
Pericarpium Citri Reticulatae [source] this product is the dry mature skin of rutaceae orange Citrus reticulata Blanco and variety thereof.[nature and flavor] are bitter, pungent, temperature.[return through] returns lung, spleen channel.
[function cures mainly] regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Radix Saposhnikoviae [source] this product is the dry root of umbelliferae Saposhnikovia divaricata Saposhnikovia divaricata (Turcz.) Schischk..[nature and flavor] acrid, sweet, warm.[return through] returns bladder, liver, spleen channel.[function cures mainly] inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.
Semen Coicis [source] this product is the dry mature kernal of grass Semen Coicis Coix lacryma-jobi L. var. ma-yuen (Roman.) Stapf.[nature and flavor] are sweet, light, cool.[return through] returns spleen, stomach, lung meridian.[function cures mainly] spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, row is dense in heat clearing away.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.
Herba Leonuri [source] this product is the fresh or dry aerial parts of labiate Herba Leonuri Leonurus japonicus Houtt..[nature and flavor] are bitter, pungent, are slightly cold.[return through] returns liver, pericardium channel.[function cures mainly] promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.
Rhizoma Cyperi [source] this product is the dry rhizome of sedge dried tuber Cyperus rotundus L..[nature and flavor] pungent, micro-hardship, micro-sweet, flat.[return through] returns liver, spleen, tri-jiao channel.
[function cures mainly] promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Fructus Corni [source] this product is the drying and ripening sarcocarp of Cornaceae plant Fructus Corni Cornus officinalis Sieb. et Zucc..[nature and flavor] are sour, puckery, tepor.[return through] returns liver, kidney channel.[function cures mainly] liver and kidney tonifying, essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed.
Cortex Albiziae [source] this product is the dry bark of leguminous plant Herba Albiziae Albizia julibrissin Durazz..[nature and flavor] are sweet, flat.[return through] GUIXIN, liver, lung meridian.[function cures mainly] resolving stagnation for tranquilization, promoting blood circulation and detumescence.For irritability, melancholy insomnia, lung abscess skin ulcer swells, and falls and flutters the pain of injury.
Radix Polygalae [source] this product is the dry root of milk wort Radix Polygalae Polygala tenuifolia Willd. or ovum leaf Radix Polygalae Polygala sibirica L..[nature and flavor] are bitter, pungent, warm.[return through] GUIXIN, kidney, lung meridian.[function cures mainly] to be calmed the nerves Fructus Alpiniae Oxyphyllae, is eliminated the phlegm, detumescence.For the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Semen Ziziphi Spinosae [source] this product is the dry mature seed of Rhamnaceae plant Ziziphi Spinosae Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H.F.Chou.[nature and flavor] are sweet, sour, flat.[return through] returns liver, gallbladder, heart channel.[function cures mainly] tonifying liver, mind calming, arresting sweating, promotes the production of body fluid.For restlessness of asrhenia type and insomnia, palpitation with fear dreaminess, the empty hyperhidrosis of body, Tianjin wound is thirsty.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The traditional Chinese medical science is thought: stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea many because of feelings will unsuccessful, depressed rage impairing the liver, the liver losing its smoothly moving state, hyperactive liver-QI attacking the spleen, horizontal take advantage of spleen soil, mechanism of qi pent-up, caused by dysfunction of the spleen in transportation and transformation; Depression of liver-QI, causes the performances such as patient's irritable, distending pain of the breast, stagnation of liver-QI hematogenous blockage and to cause menses dim red in clot; Depression of liver-QI then catharsis is unfavorable, and the syndrome based on digestive function weakness, appears in temper also therefore transformation failure of spleen, thus causes the source of vital function not enough, and depletion of blood is assigned punching and appointed uterus and cause infrequent menstruation.Stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea, visible menstrual cycle is indefinite clinically, more or less mensis in amount, and color is purplish red, has block, blockage of menstruation, or has the breast side of body, breast, distention and pain in the lower abdomen, oppression sensation over the epigastrium, and time sighs, heating installation lack of appetite, white and thin fur or book Huang, stringy pulse.The present invention adopts suitable medical material and proportioning thereof, cooperatively interacts between each medicine, synergism, and made Chinese medicine has effect of tonifying the spleen and stomach, qi and blood invigorating, invigorating the spleen and relieving depression of liver-QI, effectively can treat stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea disease.Over 3 years, by showing the use of 100 patients, effective percentage reaches 92%.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor have collected the sick out-patients of 160 routine stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea altogether between in June ,-2013 in June, 2010, wherein, age 23-44 year, the state of an illness 4 months-2 years.Be divided at random: treatment group 100 example, matched group 60 example.The data there was no significant differences such as two groups of ages, have comparability.
2, test method
The oral XIAOYAO KELI of 2.1 matched group, takes to specifications.20 days courses for the treatment of.
The oral the present invention of 2.2 treatment group according to the obtained capsule of specific embodiment 1, early, middle and late each once.20 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterions of therapeutical effect:
Recovery from illness: the clinical symptoms of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea disease all disappears.Take a turn for the better: the clinical symptom relief of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea disease, the state of an illness is controlled.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 100 | 32 | 61 | 7 | 93% |
| Matched group | 60 | 9 | 31 | 20 | 66．7% |
As can be seen here, the medicine adopting prescription of the present invention obtained can safe treatment stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea disease.
Detailed description of the invention
In order to Comprehension and Implementation the present invention better, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take Radix Bupleuri 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, 30 grams, Poria, Radix Angelicae Sinensis 12 grams, the Radix Paeoniae Alba 30 grams, Cortex Moutan 10 grams, Fructus Gardeniae 10 grams, Os Draconis 15 grams, Concha Ostreae 30 grams, Pericarpium Citri Reticulatae 15 grams, Radix Saposhnikoviae 6 grams, Semen Coicis 20 grams, Herba Leonuri 30 grams, Rhizoma Cyperi 20 grams, Fructus Corni 30 grams, Cortex Albiziae 20 grams, Radix Polygalae 10 grams, Semen Ziziphi Spinosae 30 grams, 6 grams, Radix Glycyrrhizae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea sick.Oral, every bu is taken for early, middle and late three times.
Specific embodiment 2
Take Radix Bupleuri 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, 30 grams, Poria, Radix Angelicae Sinensis 12 grams, the Radix Paeoniae Alba 30 grams, Cortex Moutan 10 grams, Fructus Gardeniae 10 grams, Os Draconis 15 grams, Concha Ostreae 30 grams, Pericarpium Citri Reticulatae 15 grams, Radix Saposhnikoviae 6 grams, Semen Coicis 20 grams, Herba Leonuri 30 grams, Rhizoma Cyperi 20 grams, Fructus Corni 30 grams, Cortex Albiziae 20 grams, Radix Polygalae 10 grams, Semen Ziziphi Spinosae 30 grams, 6 grams, Radix Glycyrrhizae, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's 1 day consumption.
Be used for the treatment of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea sick.Oral, every bu is taken for early, middle and late three times.
Specific embodiment 3
Take Radix Bupleuri 10 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, 30 grams, Poria, Radix Angelicae Sinensis 12 grams, the Radix Paeoniae Alba 30 grams, Cortex Moutan 10 grams, Fructus Gardeniae 10 grams, Os Draconis 15 grams, Concha Ostreae 30 grams, Pericarpium Citri Reticulatae 15 grams, Radix Saposhnikoviae 6 grams, Semen Coicis 20 grams, Herba Leonuri 30 grams, Rhizoma Cyperi 20 grams, Fructus Corni 30 grams, Cortex Albiziae 20 grams, Radix Polygalae 10 grams, Semen Ziziphi Spinosae 30 grams, 6 grams, Radix Glycyrrhizae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, granulate according to this area common process, packaging, must meet the granule of adult normal's 1 day consumption.
Be used for the treatment of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea sick.Oral, every bu is taken for early, middle and late three times.
Claims (1)
1. treat the Chinese medicine of stagnation of liver-QI with deficiency of the spleen pattern of syndrome hypomenorrhea disease for one kind, it is characterized in that being made up of the medical material of following weight proportion: Radix Bupleuri 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 30 parts, Poria, Radix Angelicae Sinensis 12 parts, the Radix Paeoniae Alba 30 parts, Cortex Moutan 10 parts, Fructus Gardeniae 10 parts, Os Draconis 15 parts, Concha Ostreae 30 parts, Pericarpium Citri Reticulatae 15 parts, Radix Saposhnikoviae 6 parts, Semen Coicis 20 parts, Herba Leonuri 30 parts, Rhizoma Cyperi 20 parts, Fructus Corni 30 parts, Cortex Albiziae 20 parts, Radix Polygalae 10 parts, Semen Ziziphi Spinosae 30 parts, 6 parts, Radix Glycyrrhizae.
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| 丹栀逍遥散加减治疗月经病临床应用概述;杨可可;《实用中医药杂志》;20121031;第28卷(第10期);第888页左栏第1段,第4段 * |
| 月经不调和带下病的调治大法;沈宁;《中国中医基础医学杂志》;20060131;第12卷(第1期);第67页左栏第2、5段和右栏第2段 * |
| 月经过少的中医诊治;王妞妞等;《现代中西医结合杂志》;20090430;第18卷(第11期);第1267页右栏第3-4段 * |
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