CN105031548A - Medicinal preparation for treating cystic hyperplasia of breasts - Google Patents
Medicinal preparation for treating cystic hyperplasia of breasts Download PDFInfo
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- CN105031548A CN105031548A CN201510551163.3A CN201510551163A CN105031548A CN 105031548 A CN105031548 A CN 105031548A CN 201510551163 A CN201510551163 A CN 201510551163A CN 105031548 A CN105031548 A CN 105031548A
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Abstract
The invention belongs to the field of traditional Chinese medicine preparations and provides a medicinal preparation for treating cystic hyperplasia of breasts. The medicinal preparation comprises, by weight, 30 parts of balanophora involucrata, 25 parts of anemone rivularis, 20 parts of heteropanax fragrans, 25 parts of passiflora moluccana, 15 parts of radix bupleuri, 25 parts of curcuma aromatica, 25 parts of caulis spatholobi, 25 parts of dandelions, 15 parts of fructus gardeniae, 15 parts of angelica sinensis, 25 parts of radix paeoniae alba, 18 parts of oysters, 25 parts of schizonepeta, 12 parts of saposhnicovia divaricata, 30 parts of leonurus, 20 parts of rhizoma cyperi, 25 parts of snakegourd fruits and 10 parts of liquorice. The medicinal preparation can treat cystic hyperplasia of breasts.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of pharmaceutical preparation and the preparation method and application that treat cystic hyperplasia of breast.
Background technology
Cystic hyperplasia of breast is that women is common, one of frequently-occurring disease, and be more common in 25 ~ 45 years old women, it is the disorder of the mammary gland normal configuration that a kind of physiology hypertrophy and subinvolution cause in essence.In China, Cystic changes is rare, is main mainly with glandular hyperplasia, therefore many titles " cyclomastopathy "." benign breast dysplasia " is referred to as by World Health Organization (WHO) (WHO).The dangerous compared with normal women that primary disease cancerates increases by 2 ~ 4 times, and clinical symptoms and sign are mixed mutually with breast carcinoma sometimes.Be the cyst that formed with lobules of mammary gland ductule and the expansion of tip catheter height for feature, with the disease of mammary dysplasia pathological changes also known as cystic hyperplasia of breast, Cystic decortication cyclomastopathy, fibrocystic disease of breast etc.Compared with pure cyclomastopathy, this sick cyclomastopathy and atypical hyperplasia coexist, and there is the danger of cancerating, and are difference places.Precancerous lesion should be considered as.Facts have proved, Chinese medicine is of great significance treatment primary disease and prognosis tool, has potential advantage and wide DEVELOPMENT PROSPECT.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of pharmaceutical preparation and the preparation method and application that treat cystic hyperplasia of breast.
Technical scheme: the object of the invention is by following scheme realize:
Treat a pharmaceutical preparation for cystic hyperplasia of breast, it is prepared by the raw material of following parts by weight: Herba balanophorae involucratae 30 parts, Herba Veronicastri Sibirici 25 parts, 20 parts, heavy curtain umbrella maple, Herba passiflorae cochinchinensis 25 parts, Radix Bupleuri 15 parts, Radix Curcumae 25 parts, Caulis Spatholobi 25 parts, Herba Taraxaci 25 parts, Fructus Gardeniae 15 parts, Radix Angelicae Sinensis 15 parts, the Radix Paeoniae Alba 25 parts, Concha Ostreae 18 parts, Herba Schizonepetae 25 parts, Radix Saposhnikoviae 12 parts, Herba Leonuri 30 parts, Rhizoma Cyperi 20 parts, Fructus Trichosanthis 25 parts, 10 parts, Radix Glycyrrhizae.
The application of pharmaceutical preparation in the medicine of preparation treatment cystic hyperplasia of breast of described treatment cystic hyperplasia of breast.
Herba balanophorae involucratae, Classification system BalanophorainvolucrataHook.F. is the herb of Balanophora japonica Mak section plant cylinder sheath Balanophora japonica Mak.To regulate the flow of vital energy stomach invigorating, clearing away heat-damp and promoting diuresis, removing toxic substances.Control peratodynia, jaundice, hemorrhoid.
Herba Veronicastri Sibirici is Ranunculaceae thimbleweed two discrimination Anemone cathayensis Kitag. AnemonedichotomaL., is used as medicine with root stock.Autumn uproots, and dries, removing toxic substances dysentery relieving, relaxing muscles and tendons to promote blood circulation.For dysentery, furuncle carbuncle poison, traumatic injury.
Heavy curtain umbrella maple is Araliaceae, Heteropanax aiphyllium, and Classification system Heteropanaxfragrans (Roxb.) Seem., is used as medicine with root, energy heat-clearing and toxic substances removing, promoting blood circulation and detumescence, pain relieving.For flu, heatstroke is had a headache; Carbuncle furuncle and phyma poison is controlled in external, lymphadenitis, fracture, burn and scald, bruise, venom.
Herba passiflorae cochinchinensis is Passifloraceae Passiflora plant Herba passiflorae cochinchinensis PassifloracochinchinensisSpreng., is used as medicine with Herb.The whole year can adopt, and cleans chopping, dries.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For venom, taste-blindness rate; Panaris is controlled in external, carbuncle sore.All the other medicines all meet standards of pharmacopoeia or are documented in Chinese medicine voluminous dictionary.
Beneficial effect: the traditional Chinese medical science thinks that the generation of cystic hyperplasia of breast and liver, stomach, punching to be appointed etc. and had substantial connection, and woman's nipple belongs to liver, and breast belongs to stomach.Rush the sea of appointing for QI and blood, upper behavior milk, descending is then through water, controls head work as dispersing the stagnated live-QI to relieve the stagnation of QI from pathogenesis opinion, secondary suitable Chong and Ren Meridians regulating deficiency of kidney yin, and the last of the ten Heavenly stems, water did not fill, and smart ovum loses supports, and can not reach maturity.Herba balanophorae involucratae of the present invention, Herba Veronicastri Sibirici, heavy curtain umbrella maple, Herba passiflorae cochinchinensis, Radix Bupleuri, Radix Curcumae, Caulis Spatholobi, Herba Taraxaci, Fructus Gardeniae dispersing the stagnated live-QI to relieve the stagnation of QI, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling are monarch drug, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Concha Ostreae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Leonuri, Rhizoma Cyperi, Fructus Trichosanthis dissipating phlegm and resolving masses, blood circulation promoting and blood stasis dispelling are ministerial drug, Radix Glycyrrhizae is adjuvant, coordinating the actions of various ingredients in a prescription, full side's compatibility has effect of blood circulation promoting and blood stasis dispelling, dispersing the stagnated live-QI to relieve the stagnation of QI, is used for the treatment of cystic hyperplasia of breast.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1. prepare embodiment
1.1 take Herba balanophorae involucratae 30g, Herba Veronicastri Sibirici 25g, heavy curtain umbrella maple 20g, Herba passiflorae cochinchinensis 25g, Radix Bupleuri 15g, Radix Curcumae 25g, Caulis Spatholobi 25g, Herba Taraxaci 25g, Fructus Gardeniae 15g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 25g, Concha Ostreae 18g, Herba Schizonepetae 25g, Radix Saposhnikoviae 12g, Herba Leonuri 30g, Rhizoma Cyperi 20g, Fructus Trichosanthis 25g, Radix Glycyrrhizae 10g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.Be used for the treatment of cystic hyperplasia of breast.Oral, every bu is taken for twice sooner or later.
1.2 take Herba balanophorae involucratae 30g, Herba Veronicastri Sibirici 25g, heavy curtain umbrella maple 20g, Herba passiflorae cochinchinensis 25g, Radix Bupleuri 15g, Radix Curcumae 25g, Caulis Spatholobi 25g, Herba Taraxaci 25g, Fructus Gardeniae 15g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 25g, Concha Ostreae 18g, Herba Schizonepetae 25g, Radix Saposhnikoviae 12g, Herba Leonuri 30g, Rhizoma Cyperi 20g, Fructus Trichosanthis 25g, Radix Glycyrrhizae 10g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add 50g starch, technique is granulated routinely, must meet the granule of adult normal's 1 day consumption.Be used for the treatment of cystic hyperplasia of breast.Oral, every bu is taken for twice sooner or later.
1.3 take Herba balanophorae involucratae 30g, Herba Veronicastri Sibirici 25g, heavy curtain umbrella maple 20g, Herba passiflorae cochinchinensis 25g, Radix Bupleuri 15g, Radix Curcumae 25g, Caulis Spatholobi 25g, Herba Taraxaci 25g, Fructus Gardeniae 15g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 25g, Concha Ostreae 18g, Herba Schizonepetae 25g, Radix Saposhnikoviae 12g, Herba Leonuri 30g, Rhizoma Cyperi 20g, Fructus Trichosanthis 25g, Radix Glycyrrhizae 10g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add 50g starch, technique is granulated routinely, and tabletting, can obtain the tablet meeting adult normal's 1 day consumption.Be used for the treatment of cystic hyperplasia of breast.Oral, every bu is taken for twice sooner or later.
2. the present invention is to the clinical research of cystic hyperplasia of breast
2.1 physical data: inventor collects the out-patient of 40 routine cystic hyperplasia of breast altogether between in August ,-2013 in April, 2012, age 24-37 year, be divided at random: treatment group 20 example, blank group 20 example.The data there was no significant differences such as two groups of state of an illness, have comparability.
2.2 diagnostic criterias: (one) distending pain of the breast: common is one-sided or bilateral distending pain of the breast or tenderness.The course of disease be 2 months to the several years not etc., Most patients has the feature of periodically pain, and premenstrua occurs or increases the weight of, and alleviates or disappear after menstruation.Though must be noted that the periodicity of mastalgia is the typical performance of primary disease, lack the existence that this characteristic person can not negate pathological changes.(2) lump in breast: be often multiple, one-sided or bilateral, common with outside upper quadrant; And size, quality also normal be cyclically-varying with menstruation, premenstrua lump increases, and quality is comparatively hard, mass reduction after menstruation, and matter is tough and not hard.Lay one's hand on and can to touch lump when looking in joint structure, not of uniform size, unclear with surrounding tissue boundary, there is tenderness more, with skin and deep tissue without adhesion, can be pushed, axillary gland not enlargement.
In addition, still there are course of disease length, slower development, sometimes can have the performances such as nipple discharge.The tuberosity differed in size in breast is in fact the large and small latex dust of some cryptomeres expansion, and nipple discharge are namely from these cysts, and in yellow green, brown or courageous and upright, even is colorless slurry.
2.3 test method
2.3.1 the oral the present invention for the treatment of group is according to the obtained granule of specific embodiment 1.2, sooner or later each once.30 days courses for the treatment of.
2.3.2 blank group oral placebo granule, sooner or later respectively once.30 days courses for the treatment of.
2.4 criterions of therapeutical effect and therapeutic outcome
2.4.1 criterion of therapeutical effect is cured: clinical symptoms and sign disappear; Lump in breast disappears, breast aperiodicity distending pain.Be normally through every inspection.Take a turn for the better: lump in breast quantity reduces or volume-diminished, and distending pain degree obviously alleviates.B ultrasonic, take the photograph sheet, thermal image figure etc. and confirm that cystic hyperplasia situation alleviates.Invalid: clinical symptoms is without obviously alleviating, or lump is without significant change person
2.4.2 statistical result is treated in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 20 | 7 | 12 | 1 | 95 |
| Blank group | 20 | 1 | 2 | 17 | 15 |
Visible, the medicine that the present invention obtains can safe and effective treatment cystic hyperplasia of breast, and has no side effect.
Model case and curative effect:
Case 1, Wang, female, 24 years old age, bilateral distending pain of the breast.The course of disease is 6 months, and have the feature of periodically pain, premenstrua increases the weight of, and disappears after menstruation, is diagnosed as cystic hyperplasia of breast, and take the present invention according to after specific embodiment 1.1 obtained 3 courses for the treatment of of capsule, clinical symptoms and sign disappear; Lump in breast disappears, breast aperiodicity distending pain.Be normally through every inspection.
Claims (2)
1. treat the pharmaceutical preparation of cystic hyperplasia of breast for one kind, it is characterized in that, it is prepared by the raw material of following parts by weight: Herba balanophorae involucratae 30 parts, Herba Veronicastri Sibirici 25 parts, 20 parts, heavy curtain umbrella maple, Herba passiflorae cochinchinensis 25 parts, Radix Bupleuri 15 parts, Radix Curcumae 25 parts, Caulis Spatholobi 25 parts, Herba Taraxaci 25 parts, Fructus Gardeniae 15 parts, Radix Angelicae Sinensis 15 parts, the Radix Paeoniae Alba 25 parts, Concha Ostreae 18 parts, Herba Schizonepetae 25 parts, Radix Saposhnikoviae 12 parts, Herba Leonuri 30 parts, Rhizoma Cyperi 20 parts, Fructus Trichosanthis 25 parts, 10 parts, Radix Glycyrrhizae.
2. treat the application of pharmaceutical preparation in the medicine for the treatment of cystic hyperplasia of breast of cystic hyperplasia of breast as claimed in claim 1.
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| CN201510551163.3A CN105031548A (en) | 2015-09-01 | 2015-09-01 | Medicinal preparation for treating cystic hyperplasia of breasts |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101618191A (en) * | 2009-05-27 | 2010-01-06 | 王明文 | Medicinal granule for curing mammary dysplasia and preparation method thereof |
| CN103520573A (en) * | 2013-10-21 | 2014-01-22 | 谭钦文 | Traditional Chinese medicine for treating liver depression and blood stasis syndrome type breast nodule diseases |
| CN104027744A (en) * | 2014-06-24 | 2014-09-10 | 湖州康企药业有限公司 | Medicine for treating hyperplasia of mammary glands |
-
2015
- 2015-09-01 CN CN201510551163.3A patent/CN105031548A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101618191A (en) * | 2009-05-27 | 2010-01-06 | 王明文 | Medicinal granule for curing mammary dysplasia and preparation method thereof |
| CN103520573A (en) * | 2013-10-21 | 2014-01-22 | 谭钦文 | Traditional Chinese medicine for treating liver depression and blood stasis syndrome type breast nodule diseases |
| CN104027744A (en) * | 2014-06-24 | 2014-09-10 | 湖州康企药业有限公司 | Medicine for treating hyperplasia of mammary glands |
Non-Patent Citations (2)
| Title |
|---|
| 习素娟: ""消癖安乳汤治疗乳腺增生96例体会"", 《世界中西医结合杂志》 * |
| 于峻岭: ""中医治疗乳房囊性增生病56 例"", 《基层医学论坛》 * |
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