CN105663850A - Traditional Chinese medicine composition for treating oral ulcer - Google Patents

Traditional Chinese medicine composition for treating oral ulcer Download PDF

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CN105663850A
CN105663850A CN201610131897.0A CN201610131897A CN105663850A CN 105663850 A CN105663850 A CN 105663850A CN 201610131897 A CN201610131897 A CN 201610131897A CN 105663850 A CN105663850 A CN 105663850A
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parts
radix
chinese medicine
herba
medicine composition
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刘昌红
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K33/00—Medicinal preparations containing inorganic active ingredients
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/51—Gentianaceae (Gentian family)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/808—Scrophularia (figwort)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/85—Verbenaceae (Verbena family)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

Abstract

The invention discloses a traditional Chinese medicine composition for treating oral ulcer. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of cornus officinalis, 5-25 parts of radix geutianae, 5-20 parts of root of womwoodleaf ampelocissus, 5-25 parts of reed rhizome, 5-25 parts of pratia nummularia, 5-25 parts of Chinese holly, 5-20 parts of radix zanthoxyli, 5-25 parts of dried longan pulp, 5-25 parts of dendrobium nobile, 5-20 parts of garcinia mangostana, 5-25 parts of cactus, 5-25 parts of talc, 5-25 parts of solidago decurrens, 5-20 parts of bezoar, 5-25 parts of saffron, 5-25 parts of verveine officinale, 5-20 parts of radix cynanchi atrati, 5-25 parts of salvia miltiorrhiza, 5-25 parts of herba andrographitis, 5-20 parts of sanguisorba officinalis, 5-25 parts of common wedgelet fern herb, 5-25 parts of radix scrophulariae, 5-25 parts of ampelopsis humulifolia bunge and 5-15 parts of liquorice. The traditional Chinese medicine composition disclosed by the invention has the functions of tonifying and replenishing the heart and spleen, nourishing yin and clearing heat, purging fire and removing toxin, diminishing inflammation and relieving pain and removing dampness and healing up sore, realizes a remarkable curative effect on oral ulcer and acts reliably.

Description

A kind of Chinese medicine composition treating oral ulcer
Technical field
The present invention relates to the pharmaceutical product not determining structure of a kind of traditional herbal medicines, especially a kind of Chinese medicine composition treating oral ulcer.
Background technology
Oral ulcer, also referred to as " aphtha ", is to occur at the bleeding blister on oral mucosa, big I from the grain of rice to Semen Glycines size, circular or oval, ulcer surface is that oral ulcer is recessed, congested around, can cause pain because of irritable food, and generally one or two week can spontaneous recovery. Oral ulcer becomes the cycle repeatedly to occur, and medically claims " recurrent oral ulceration ". Can fall ill for several times for 1 year, it is also possible to January falls ill several times, and even new and old pathological changes is alternately present. Oral ulcer is many in the fall and easily recur during abrupt change of climate. Clinical this disease of western medical treatment is based on vitimin supplement and antiinflammatory, but all curative effect is not good enough and the oral ulcer of Most patients can recurrent exerbation in a short period of time.
Motherland's medical science thinks that oral ulcer is how unsuccessful and undermine heart spleen by feelings will; Hyperactivity of fire caused by deficiency of YIN, pyretic toxicity is burnt bright, and inner clip is damp and hot, on steam in caused by mouth. Diseases caused by exogenous pathogenic factor six climate exopathogens dryness-fire, interior impairment of ZANG FU-organs intenseness of heat is main cause of causing a disease, and the dirty of main disease is in that the heart and spleen.
According to theory of Chinese medical science, for the pathogeny of oral ulcer, adopt the method for the treatment of of invigorating the heart and spleen, nourishing YIN and clearing away heat, eliminating fire and detoxication, anti-inflammatory analgetic, damp eliminating sore, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Treating oral ulcer in prior art there is the deficiency of the not good enough and easy recurrent exerbation of curative effect to overcome, the present invention provides and a kind of prepares simplicity, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of oral ulcer that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition treating oral ulcer, it is characterized in that: its raw material of Chinese medicine and weight be: Fructus Corni 10-30 part, Radix Gentianae 5-25 part, Radix Ampelocissi artemisiaefoilae 5-20 part, Rhizoma Phragmitis 5-25 part, Herba pratiae begonifoliae 5-25 part, Ilex purpurea Hassk.[I.chinensis Sims 5-25 part, Radix Zanthoxyli 5-20 part, Arillus Longan 5-25 part, Herba Dendrobii 5-25 part, Cortex Garciniae 5-20 part, Radix et Caulis Opuntiae Dillenii 5-25 part, Talcum 5-25 part, Herba Solidaginis 5-25 part, Calculus Bovis 5-20 part, Stigma Croci 5-25 part, Herba Verbenae 5-25 part, Radix Cynanchi Atrati 5-20 part, Radix Salviae Miltiorrhizae 5-25 part, Herba Andrographis 5-25 part, Radix Sanguisorbae 5-20 part, Folium Stenolomatis 5-25 part, Radix Scrophulariae 5-25 part, heptangle Radix Ampelopsis 5-25 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition treating oral ulcer, it is characterized in that: its raw material of Chinese medicine and weight be: Fructus Corni 20 parts, Radix Gentianae 15 parts, Radix Ampelocissi artemisiaefoilae 10 parts, Rhizoma Phragmitis 15 parts, Herba pratiae begonifoliae 15 parts, Ilex purpurea Hassk.[I.chinensis Sims 15 parts, Radix Zanthoxyli 10 parts, Arillus Longan 15 parts, Herba Dendrobii 15 parts, Cortex Garciniae 10 parts, Radix et Caulis Opuntiae Dillenii 15 parts, 15 parts of Talcum, Herba Solidaginis 15 parts, Calculus Bovis 10 parts, Stigma Croci 15 parts, Herba Verbenae 15 parts, Radix Cynanchi Atrati 10 parts, Radix Salviae Miltiorrhizae 15 parts, Herba Andrographis 15 parts, Radix Sanguisorbae 10 parts, Folium Stenolomatis 15 parts, Radix Scrophulariae 15 parts, heptangle Radix Ampelopsis 15 parts, 10 parts of Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription. In Chinese medicine composition of the present invention: Fructus Corni has effect of liver and kidney tonifying, essence astringing and desertion stemming; Radix Gentianae has effect of heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire; Radix Ampelocissi artemisiaefoilae has effect of promoting blood circulation and stopping pain, removing toxic substances sore; Rhizoma Phragmitis has effect of clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis; Herba pratiae begonifoliae has expelling wind and removing dampness、Effect of promoting blood circulation and detoxication; Ilex purpurea Hassk.[I.chinensis Sims has effect of heat-clearing and toxic substances removing, promoting tissue regeneration and ulcer healing, promoting blood circulation and hemostasis; Radix Zanthoxyli has effect of promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral; Arillus Longan has effect of invigorating the heart and spleen, nourishing blood to tranquillize the mind; Herba Dendrobii has effect of reinforcing stomach reg fluid, nourishing YIN and clearing away heat; Cortex Garciniae has anti-inflammatory analgetic、Effect of convergence granulation promoting; Radix et Caulis Opuntiae Dillenii has promoting flow of QI and blood、Heat-clearing and toxic substances removing、Cooling blood for hemostasis、Effect of clearing away lung-heat to relieve cough; Talcum has effect of inducing diuresis for treating stranguria syndrome, clearing away summer-heat, damp eliminating sore; Herba Solidaginis has effect of wind and heat dispersing, subduing swelling and detoxicating; Calculus Bovis has effect of removing heat from the heart to restore the consciousness, eliminating phlegm arresting convulsion, heat-clearing and toxic substances removing; Stigma Croci has blood circulation promoting and blood stasis dispelling、Removing pathogenic heat from blood and toxic substance from the body、Effect of resolving stagnation for tranquilization; Herba Verbenae has effect of heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, inducing diuresis to remove edema; Radix Cynanchi Atrati has effect of clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome, detoxification sore treatment; Radix Salviae Miltiorrhizae has effect of promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Herba Andrographis has effect of heat-clearing and toxic substances removing, removing heat from blood detumescence; Radix Sanguisorbae has effect of cooling blood for hemostasis, heat-clearing and toxic substances removing, detumescence sore; Folium Stenolomatis has effect of heat-clearing and toxic substances removing, dampness removing, hemostasis; Radix Scrophulariae has effect of removing heat from blood YIN nourishing, eliminating fire and detoxication; Heptangle Radix Ampelopsis has promoting blood circulation to remove blood stasis, eliminating inflammation and expelling toxin, granulation promoting long bone, effect except wind damp eliminating; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription. The selected medicament composing prescription of the present invention, its drug component, through dialectical compatibility, helps using assistant mutually, plays effect of invigorating the heart and spleen, nourishing YIN and clearing away heat, eliminating fire and detoxication, anti-inflammatory analgetic, damp eliminating sore altogether, the treatment of oral ulcer is reached treating both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and preparation is easy, medicine source is wide, cost is low for it. The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose. Verifying by clinic application, it is evident in efficacy reliably, mild in medicine property and, do not occur that toxic and side effects, effective percentage reach 97%, cure rate 78%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
A kind of Chinese medicine composition treating oral ulcer, its raw material of Chinese medicine and weight proportion be: Fructus Corni 20g, Radix Gentianae 15g, Radix Ampelocissi artemisiaefoilae 10g, Rhizoma Phragmitis 15g, Herba pratiae begonifoliae 15g, Ilex purpurea Hassk.[I.chinensis Sims 15g, Radix Zanthoxyli 10g, Arillus Longan 15g, Herba Dendrobii 15g, Cortex Garciniae 10g, Radix et Caulis Opuntiae Dillenii 15g, Talcum 15g, Herba Solidaginis 15g, Calculus Bovis 10g, Stigma Croci 15g, Herba Verbenae 15g, Radix Cynanchi Atrati 10g, Radix Salviae Miltiorrhizae 15g, Herba Andrographis 15g, Radix Sanguisorbae 10g, Folium Stenolomatis 15g, Radix Scrophulariae 15g, heptangle Radix Ampelopsis 15g, Radix Glycyrrhizae 10g.
Embodiment 2
A kind of Chinese medicine composition treating oral ulcer, its raw material of Chinese medicine and weight proportion be: Fructus Corni 15g, Radix Gentianae 25g, Radix Ampelocissi artemisiaefoilae 12g, Rhizoma Phragmitis 20g, Herba pratiae begonifoliae 5g, Ilex purpurea Hassk.[I.chinensis Sims 25g, Radix Zanthoxyli 12g, Arillus Longan 20g, Herba Dendrobii 5g, Cortex Garciniae 15g, Radix et Caulis Opuntiae Dillenii 10g, Talcum 20g, Herba Solidaginis 5g, Calculus Bovis 15g, Stigma Croci 10g, Herba Verbenae 20g, Radix Cynanchi Atrati 5g, Radix Salviae Miltiorrhizae 25g, Herba Andrographis 5g, Radix Sanguisorbae 20g, Folium Stenolomatis 10g, Radix Scrophulariae 20g, heptangle Radix Ampelopsis 5g, Radix Glycyrrhizae 15g.
Embodiment 3
A kind of Chinese medicine composition treating oral ulcer, its raw material of Chinese medicine and weight proportion be: Fructus Corni 25g, Radix Gentianae 5g, Radix Ampelocissi artemisiaefoilae 15g, Rhizoma Phragmitis 10g, Herba pratiae begonifoliae 20g, Ilex purpurea Hassk.[I.chinensis Sims 5g, Radix Zanthoxyli 15g, Arillus Longan 10g, Herba Dendrobii 20g, Cortex Garciniae 5g, Radix et Caulis Opuntiae Dillenii 25g, Talcum 10g, Herba Solidaginis 20g, Calculus Bovis 5g, Stigma Croci 25g, Herba Verbenae 10g, Radix Cynanchi Atrati 20g, Radix Salviae Miltiorrhizae 5g, Herba Andrographis 25g, Radix Sanguisorbae 12g, Folium Stenolomatis 20g, Radix Scrophulariae 5g, heptangle Radix Ampelopsis 25g, Radix Glycyrrhizae 12g.
Embodiment 4
A kind of Chinese medicine composition treating oral ulcer, its raw material of Chinese medicine and weight proportion be: Fructus Corni 10g, Radix Gentianae 20g, Radix Ampelocissi artemisiaefoilae 5g, Rhizoma Phragmitis 25g, Herba pratiae begonifoliae 10g, Ilex purpurea Hassk.[I.chinensis Sims 20g, Radix Zanthoxyli 5g, Arillus Longan 25g, Herba Dendrobii 10g, Cortex Garciniae 20g, Radix et Caulis Opuntiae Dillenii 5g, Talcum 25g, Herba Solidaginis 10g, Calculus Bovis 20g, Stigma Croci 5g, Herba Verbenae 25g, Radix Cynanchi Atrati 12g, Radix Salviae Miltiorrhizae 20g, Herba Andrographis 10g, Radix Sanguisorbae 15g, Folium Stenolomatis 5g, Radix Scrophulariae 25g, heptangle Radix Ampelopsis 10g, Radix Glycyrrhizae 5g.
Embodiment 5
A kind of Chinese medicine composition treating oral ulcer, its raw material of Chinese medicine and weight proportion be: Fructus Corni 30g, Radix Gentianae 10g, Radix Ampelocissi artemisiaefoilae 20g, Rhizoma Phragmitis 5g, Herba pratiae begonifoliae 25g, Ilex purpurea Hassk.[I.chinensis Sims 10g, Radix Zanthoxyli 20g, Arillus Longan 5g, Herba Dendrobii 25g, Cortex Garciniae 12g, Radix et Caulis Opuntiae Dillenii 20g, Talcum 5g, Herba Solidaginis 25g, Calculus Bovis 12g, Stigma Croci 20g, Herba Verbenae 5g, Radix Cynanchi Atrati 15g, Radix Salviae Miltiorrhizae 10g, Herba Andrographis 20g, Radix Sanguisorbae 5g, Folium Stenolomatis 25g, Radix Scrophulariae 10g, heptangle Radix Ampelopsis 20g, Radix Glycyrrhizae 8g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament. Concrete grammar is as follows: put in container by the raw material of Chinese medicine of prescription, adds cold water and covers powder, soak 15～20 minutes, adds water and do not have powder about 6 centimetres, carries out first time decoction, adopts intense fire to decoct before at a simmer, with slow fire boiling 20～30 minutes after boiling; Second time decocts, and adds water and did not have powder about 4 centimetres, and water decocts 15～20 minutes after boiling. Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition treating oral ulcer given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 100 example, male 57 examples, female 43 example, 15～65 years old age.
Two, diagnosis basis:
1, the ulcer of single or several diameter 3～5mm occur with oral mucosa, scorching hot pain is cardinal symptom;
2, onset is very fast, healing in general about 7 days, if down here, then the course of disease extends. More often easily recurrence after;
3, examination of mouth: stomatocace is shallow compared with table, circular or oval, quantity 1～2 at least, more than 10 at most, surface has faint yellow secretions to adhere to, and ulcer surrounding mucosa is mostly congested;
4, should differentiate mutually with inflammation around hu huo syndrome (behcet's syndrome), Periadenitis mucosa and herpetic stomatitis.
Three, usage and dosage: during clinical practice, potion on the one, twice extracting juice of decocting is about 400ml, point morning, late twice empty stomach decoction being taken warmly. It within five days, it is a course for the treatment of. Avoid cold and uncooked food during treatment the thing of pungent stimulation.
Four, criterion of therapeutical effect:
(1) recovery from illness: transference cure, ulcer surface heals, and does not recur in 1 year;
(2) effective: ulcer healing or be obviously reduced, pain substantially alleviates or disappears, and does not recur in half a year;
(3) effective: ulcer reduces, pain relief;
(4) invalid: before and after treatment, non-evident sympton improves.
Five, therapeutic effect: in this clinical observation case, take medicine 2-5 the course for the treatment of, 78 examples of fully recovering, follow up a case by regular visits to and have no recurrence; Effective 12 examples, effective 7 examples, invalid 3 examples. Toxic and side effects is there is not during treatment.
Six, model case:
Case 1:
Korea Spro, female, 36 years old. Time medical, Symptoms is: oral mucosa pain, has three to five place's ulcer, and diameter is about 10-30mm, more than 1 day persistent period, and secretions increases, and drinking-water and feed are hindered, and there is burning sensation at ulcer place, and tongue limit has tooth to print, thin white fur of tongue. Taking 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, oral mucosa pain weakens, and ulcer number reduces, and burning sensation disappears; Continuing to take 3 courses for the treatment of, above-mentioned symptom is wholly absent, and ulcer surface heals, painless, can normally take food and drink water, and cures. Follow up a case by regular visits to and do not recur again half a year.
Case 2:
High mountain, man, 47 years old. Readme oral mucosa ulcer half a year repeatedly, the treatment of multiple method was once adopted to have no improvement. Taking 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom substantially alleviates; Continuing to take 2 courses for the treatment of, transference cure, ulcer surface heals, and cures. Follow up a case by regular visits to and do not recur again so far.

Claims (2)

1. the Chinese medicine composition treating oral ulcer, it is characterized in that: its raw material of Chinese medicine and weight be: Fructus Corni 10-30 part, Radix Gentianae 5-25 part, Radix Ampelocissi artemisiaefoilae 5-20 part, Rhizoma Phragmitis 5-25 part, Herba pratiae begonifoliae 5-25 part, Ilex purpurea Hassk.[I.chinensis Sims 5-25 part, Radix Zanthoxyli 5-20 part, Arillus Longan 5-25 part, Herba Dendrobii 5-25 part, Cortex Garciniae 5-20 part, Radix et Caulis Opuntiae Dillenii 5-25 part, Talcum 5-25 part, Herba Solidaginis 5-25 part, Calculus Bovis 5-20 part, Stigma Croci 5-25 part, Herba Verbenae 5-25 part, Radix Cynanchi Atrati 5-20 part, Radix Salviae Miltiorrhizae 5-25 part, Herba Andrographis 5-25 part, Radix Sanguisorbae 5-20 part, Folium Stenolomatis 5-25 part, Radix Scrophulariae 5-25 part, heptangle Radix Ampelopsis 5-25 part, Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine composition treating oral ulcer according to claim 1, it is characterized in that: its raw material of Chinese medicine and weight be: Fructus Corni 20 parts, Radix Gentianae 15 parts, Radix Ampelocissi artemisiaefoilae 10 parts, Rhizoma Phragmitis 15 parts, Herba pratiae begonifoliae 15 parts, Ilex purpurea Hassk.[I.chinensis Sims 15 parts, Radix Zanthoxyli 10 parts, Arillus Longan 15 parts, Herba Dendrobii 15 parts, Cortex Garciniae 10 parts, Radix et Caulis Opuntiae Dillenii 15 parts, 15 parts of Talcum, Herba Solidaginis 15 parts, Calculus Bovis 10 parts, Stigma Croci 15 parts, Herba Verbenae 15 parts, Radix Cynanchi Atrati 10 parts, Radix Salviae Miltiorrhizae 15 parts, Herba Andrographis 15 parts, Radix Sanguisorbae 10 parts, Folium Stenolomatis 15 parts, Radix Scrophulariae 15 parts, heptangle Radix Ampelopsis 15 parts, 10 parts of Radix Glycyrrhizae.
CN201610131897.0A 2016-03-09 2016-03-09 Traditional Chinese medicine composition for treating oral ulcer Pending CN105663850A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177038A (en) * 2016-07-30 2016-12-07 孟庆美 A kind of Chinese medicine preparation treating recurrent oral ulceration

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177038A (en) * 2016-07-30 2016-12-07 孟庆美 A kind of Chinese medicine preparation treating recurrent oral ulceration

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