CN104173667A - Traditional Chinese medicine composition for treating osteoarthritis - Google Patents
Traditional Chinese medicine composition for treating osteoarthritis Download PDFInfo
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- CN104173667A CN104173667A CN201410420671.3A CN201410420671A CN104173667A CN 104173667 A CN104173667 A CN 104173667A CN 201410420671 A CN201410420671 A CN 201410420671A CN 104173667 A CN104173667 A CN 104173667A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating osteoarthritis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medical materials in parts by weight: 10-40 parts of prepared rehmannia roots, 5-25 parts of rhizoma alismatis, 10-40 parts of Chinese yams, 5-20 parts of radix aconiti carmichaeli, 10-40 parts of dogwood, 5-25 parts of cassia twig, 10-30 parts of semen plantaginis, 5-20 parts of morinda officinalis, 5-25 parts of rhizoma drynariae, 10-40 parts of garden balsam stems, 5-20 parts of pyrola, 10-40 parts of radix paeoniae alba, 10-30 parts of lanatechead saussurea herb with flowers, 10-40 parts of kamuning, 5-25 parts of eucommia ulmoides, 5-25 parts of homalomena occulta, 5-20 parts of large-leaved gentian, 10-30 parts of corydalis tubers, 5-25 parts of corydalis amabilis, 10-40 parts of radix angelicae, 5-25 parts of sargent gloryvine, 10-30 parts of herba siegesbeckiae and 5-15 parts of liquorice. The traditional Chinese medicine composition provided by the invention has the functions of nourishing the liver and kidneys, relaxing tendons and activating collaterals, promoting blood circulation to remove blood stasis, eliminating cold to stop pain and dispelling wind and eliminating dampness, and is remarkable in curative effect and reliable in effect for treating osteoarthritis.
Description
Technical field
The present invention relates to a kind of not pharmaceutical product of definite structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of osteoarthritis.
Background technology
Osteoarthritis (osteoarthritis, OA) also claims degenerative osteoarthritis, is the chronic joint disease that a kind of degeneration, destruction and hyperosteogeny of take articular cartilage is feature.Be mainly in middle-aged and elderly people.Main manifestations is arthralgia and movable dumb, and X line performance joint space narrows down, and subchondral bone matter is fine and close, and bone trabecula fracture, has sclerosis and cystis degeneration, and there is lip sample hypertrophy at edge, joint, later stage epiphysis distortion, and articular surface is uneven.At present, western medical treatment comprises operative treatment, non-operative treatment and naturopathy.Operative treatment itself is exactly a kind of traumatic treatment, and is prone to infection, blood vessel, nerve injury, and skin, osteonecrosis, the bad complication such as joint motion is limited, curative effect is also unstable; What non-operative treatment was the most frequently used is exactly to take analgesic and antibiotic medicine, but this method cannot solve the basic Autoimmune Disorders pathomechanism of osteoarthritis, and this type of medicine of long-term taking can cause addiction to rely on and gastrointestinal destroys; Though naturopathy has certain effect, the course for the treatment of is long, and curative effect is not consolidated.
The traditional Chinese medical science thinks, osteoarthritis belongs to Chinese medicine " rheumatism involving the bone ", " knee joint numbness " category.Osteoarthritis is many because of caused by liver and kidney deficiency, the evil invasion muscles and bones of wind and cold wet three, and phlegm-damp blood stasis knot is sent out with joint and is due to pain.
According to theory of Chinese medical science, for the pathogeny of osteoarthritis, adopt the method for the treatment of of nourishing the liver and kidney, relaxing muscles and tendons and activating QI and blood in the collateral, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome, in prior art, to treat osteoarthritis and have the deficiency that the course for the treatment of is long, curative effect is undesirable, the invention provides a kind of prepare easy, cost is low, the Chinese medicine composition of evident in efficacy, the treatment osteoarthritis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of osteoarthritis, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Rehmanniae Preparata 10-40 part, Rhizoma Alismatis 5-25 part, Rhizoma Dioscoreae 10-40 part, Radix Aconiti Lateralis Preparata 5-20 part, Fructus Corni 10-40 part, Ramulus Cinnamomi 5-25 part, Semen Plantaginis 10-30 part, Radix Morindae Officinalis 5-20 part, Rhizoma Drynariae 5-25 part, Herba speranskiae tuberculatae 10-40 part, Herba Pyrolae 5-20 part, Radix Paeoniae Alba 10-40 part, Herba Saussureae Involueratae 10-30 part, Folium Et Cacumen Murrayae 10-40 part, Cortex Eucommiae 5-25 part, Rhizoma Homalomenae 5-25 part, Radix Gentianae Macrophyllae 5-20 part, Rhizoma Corydalis 10-30 part, Rhizoma Corydalis Decumbentis 5-25 part, Radix Angelicae Dahuricae 10-40 part, Caulis Sargentodoxae 5-25 part, Herba Siegesbeckiae 10-30 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of osteoarthritis, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 30 parts of Radix Rehmanniae Preparata, 15 parts of Rhizoma Alismatis, 30 parts of Rhizoma Dioscoreaes, 10 parts of Radix Aconiti Lateralis Preparatas, 30 parts of Fructus Corni, 15 parts of Ramulus Cinnamomi, 20 parts of Semen Plantaginiss, 10 parts of Radix Morindae Officinaliss, 15 parts of Rhizoma Drynariae, 30 parts of Herba speranskiae tuberculataes, 10 parts of Herba Pyrolaes, 30 parts of the Radix Paeoniae Albas, 20 parts of Herba Saussureae Involuerataes, 30 parts of Folium Et Cacumen Murrayae, 15 parts of the Cortexs Eucommiae, 15 parts of Rhizoma Homalomenaes, 10 parts of Radix Gentianae Macrophyllae, 20 parts of Rhizoma Corydalis, 15 parts of Rhizoma Corydalis Decumbentiss, 30 parts of the Radixs Angelicae Dahuricae, 15 parts of Caulis Sargentodoxaes, 20 parts of Herba Siegesbeckiaes, 10 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: Radix Rehmanniae Preparata has the effect of the yin nourishing of enriching blood, life essence-filling, marrow-benefitting; Rhizoma Alismatis has promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil; Rhizoma Dioscoreae has strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, the benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, grow that will is calmed the nerves, the effect of life lengthening; Radix Aconiti Lateralis Preparata has recuperating depleted YANG and rescuing the patient from collapse, mends effect fiery supporing yang, dispersing cold for relieving pain; Fructus Corni has the effect of liver and kidney tonifying, essence astringing and desertion stemming; Ramulus Cinnamomi has the effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; Semen Plantaginis has the effect of relieving stranguria by diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat-phlegm; Radix Morindae Officinalis has the effect of reinforcing the kidney and supporting YANG, bone and muscle strengthening, expelling wind and removing dampness; Rhizoma Drynariae has the kidney invigorating bone strengthening, continuous effect of hindering pain relieving; Herba speranskiae tuberculatae has the effect that expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation and stopping pain, solution poison rash; Herba Pyrolae has the kidney invigorating bone strengthening
,expelling wind and removing dampness
,cough-relieving
,the effect of hemostasis; The Radix Paeoniae Alba has the effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Herba Saussureae Involueratae has kidney invigorating and YANG supporting, the effect of regulating menstruation, hemostasis; Folium Et Cacumen Murrayae has promoting the circulation of QI to relieve pain, the effect of promoting blood circulation to remove blood stasis; The Cortex Eucommiae has the effect of invigorating the liver and kidney, bone and muscle strengthening, invigorating middle warmer benefit vital essence; Rhizoma Homalomenae has the effect of wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, alleviating pain and detumescence; Radix Gentianae Macrophyllae has the effect of Eradicates rheumatism, relaxing muscles and tendons network, clearind deficient heat; Rhizoma Corydalis has the effect of promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving; Rhizoma Corydalis Decumbentis has promoting blood circulation to remove obstruction in the collateral
,the effect of promoting the circulation of QI to relieve pain; The Radix Angelicae Dahuricae has the effect of the cold expelling that induces sweat, expelling pathogenic wind and restoring the functions of orifices in face, promoting blood circulation and stopping pain, dampness leukorrhagia stopping, detumescence and apocenosis; Caulis Sargentodoxae has heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral, the effect of the dissipating blood stasis that relieves internal heat, wind dispelling insecticide; Herba Siegesbeckiae has the effect of expelling wind and removing dampness, dredge the meridian passage, heat-clearing and toxic substances removing; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, helps using mutual assistant, plays altogether the effect of nourishing the liver and kidney, relaxing muscles and tendons and activating QI and blood in the collateral, blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain, expelling wind and removing dampness, and the treatment of osteoarthritis is reached to treating both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, does not occur toxic and side effects, and effective percentage reaches 94%, cure rate 68%.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae Preparata 30g, Rhizoma Alismatis 15g, Rhizoma Dioscoreae 30g, Radix Aconiti Lateralis Preparata 10g, Fructus Corni 30g, Ramulus Cinnamomi 15g, Semen Plantaginis 20g, Radix Morindae Officinalis 10g, Rhizoma Drynariae 15g, Herba speranskiae tuberculatae 30g, Herba Pyrolae 10g, Radix Paeoniae Alba 30g, Herba Saussureae Involueratae 20g, Folium Et Cacumen Murrayae 30g, Cortex Eucommiae 15g, Rhizoma Homalomenae 15g, Radix Gentianae Macrophyllae 10g, Rhizoma Corydalis 20g, Rhizoma Corydalis Decumbentis 15g, Radix Angelicae Dahuricae 30g, Caulis Sargentodoxae 15g, Herba Siegesbeckiae 20g, Radix Glycyrrhizae 10g.
Embodiment 2
Treat a Chinese medicine composition for osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae Preparata 15g, Rhizoma Alismatis 25g, Rhizoma Dioscoreae 10g, Radix Aconiti Lateralis Preparata 20g, Fructus Corni 15g, Ramulus Cinnamomi 25g, Semen Plantaginis 10g, Radix Morindae Officinalis 15g, Rhizoma Drynariae 5g, Herba speranskiae tuberculatae 40g, Herba Pyrolae 12g, Radix Paeoniae Alba 35g, Herba Saussureae Involueratae 10g, Folium Et Cacumen Murrayae 40g, Cortex Eucommiae 5g, Rhizoma Homalomenae 25g, Radix Gentianae Macrophyllae 12g, Rhizoma Corydalis 30g, Rhizoma Corydalis Decumbentis 5g, Radix Angelicae Dahuricae 40g, Caulis Sargentodoxae 10g, Herba Siegesbeckiae 30g, Radix Glycyrrhizae 12g.
Embodiment 3
Treat a Chinese medicine composition for osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae Preparata 25g, Rhizoma Alismatis 5g, Rhizoma Dioscoreae 40g, Radix Aconiti Lateralis Preparata 15g, Fructus Corni 10g, Ramulus Cinnamomi 20g, Semen Plantaginis 15g, Radix Morindae Officinalis 12g, Rhizoma Drynariae 25g, Herba speranskiae tuberculatae 15g, Herba Pyrolae 20g, Radix Paeoniae Alba 10g, Herba Saussureae Involueratae 30g, Folium Et Cacumen Murrayae 20g, Cortex Eucommiae 10g, Rhizoma Homalomenae 20g, Radix Gentianae Macrophyllae 5g, Rhizoma Corydalis 15g, Rhizoma Corydalis Decumbentis 20g, Radix Angelicae Dahuricae 10g, Caulis Sargentodoxae 25g, Herba Siegesbeckiae 15g, Radix Glycyrrhizae 5g.
Embodiment 4
Treat a Chinese medicine composition for osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae Preparata 10g, Rhizoma Alismatis 20g, Rhizoma Dioscoreae 15g, Radix Aconiti Lateralis Preparata 5g, Fructus Corni 25g, Ramulus Cinnamomi 10g, Semen Plantaginis 25g, Radix Morindae Officinalis 5g, Rhizoma Drynariae 20g, Herba speranskiae tuberculatae 10g, Herba Pyrolae 15g, Radix Paeoniae Alba 25g, Herba Saussureae Involueratae 15g, Folium Et Cacumen Murrayae 10g, Cortex Eucommiae 20g, Rhizoma Homalomenae 5g, Radix Gentianae Macrophyllae 15g, Rhizoma Corydalis 25g, Rhizoma Corydalis Decumbentis 5g, Radix Angelicae Dahuricae 20g, Caulis Sargentodoxae 5g, Herba Siegesbeckiae 25g, Radix Glycyrrhizae 8g.
Embodiment 5
Treat a Chinese medicine composition for osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae Preparata 40g, Rhizoma Alismatis 10g, Rhizoma Dioscoreae 25g, Radix Aconiti Lateralis Preparata 12g, Fructus Corni 40g, Ramulus Cinnamomi 5g, Semen Plantaginis 30g, Radix Morindae Officinalis 15g, Rhizoma Drynariae 10g, Herba speranskiae tuberculatae 35g, Herba Pyrolae 5g, Radix Paeoniae Alba 40g, Herba Saussureae Involueratae 25g, Folium Et Cacumen Murrayae 15g, Cortex Eucommiae 25g, Rhizoma Homalomenae 10g, Radix Gentianae Macrophyllae 20g, Rhizoma Corydalis 10g, Rhizoma Corydalis Decumbentis 25g, Radix Angelicae Dahuricae 15g, Caulis Sargentodoxae 20g, Herba Siegesbeckiae 10g, Radix Glycyrrhizae 15g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 6 centimetres of powder, decoct for the first time, adopt intense fire to decoct before at a simmer, after boiling with slow fire boiling 20～30 minutes; Decoct for the second time, add water and do not have approximately 4 centimetres of powder, after water boils, decoct 15～20 minutes.Decoct extracting juice twice, merge.
The present invention, with the given a kind of Chinese medicine composition for the treatment of osteoarthritis of embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 50 examples, male 27 examples, female's 23 examples, 40～75 years old age.
Two, diagnosis basis: the osteoarthritis diagnostic criteria of the reference < < of State Administration of Traditional Chinese Medicine traditional Chinese medical science disease Standardization of diagnosis and curative effect > > formulation in 1994:
1, mostly be middle-aged and elderly people;
2, the periarticular pain of outbreak repeatedly, when bear a heavy burden in joint, pain increases the weight of, time have swelling;
While 3, bending and stretching joint, there is coarse joint crepitus more;
4, X line shows edge, joint hyperosteogeny, and joint space obviously narrows down;
5, rheumatoid arthritis except.
Three, usage and dosage: during clinical practice, potion on the one, the about 400ml of twice extracting juice of decocting, minute morning, late twice empty stomach decoction being taken warmly.It within six days, is a course for the treatment of.Avoid cold and uncooked food during the treatment thing of pungent stimulation.
Four, criterion of therapeutical effect: the osteoarthritis efficacy assessment standard of the reference < < of State Administration of Traditional Chinese Medicine traditional Chinese medical science disease Standardization of diagnosis and curative effect > > formulation in 1994:
(1), cure: pain disappears, and it is normal that joint movement function recovers;
(2), effective: pain obviously alleviates, and joint movement function improves;
(3), effective: pain alleviates to some extent, and joint motion makes moderate progress;
(4), invalid: arthralgia and range of activity are without improvement.
Five, therapeutic effect: in this clinical observation case, take medicine 2-8 the course for the treatment of, recovery from illness 34 examples, follow up a case by regular visits to and have no recurrence; Effective 8 examples, effective 5 examples, invalid 3 examples.During treatment, there is not toxic and side effects.
Six, model case:
Case 1: Lee, man, 43 years old.Before 2 years, there is double knee joint pain, limitation of activity, the Drug therapy such as oral meloxicam, acetaminophen once, but poor effect.Double knee joint pain increases the weight of in this year, and film making shows double knee joint regression, and joint space is asymmetric, is diagnosed as: two knee osteoarthritiss.Take 4 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, conscious double knee joint pain obviously alleviates before; Continue to take 3 courses for the treatment of, pain disappears, and it is normal that joint movement function recovers, and cures.
Case 2: soup, female, 56 years old.Two knee joint swelling, weak, pain, squat down limited.There is swelling, the pain symptom aggravation of double knee joint in the later stage.Be diagnosed as: two knee osteoarthritiss.Take 4 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, double knee joint pain, swelling alleviate greatly, and the function of squatting down is obviously improved; Continue to take 2 courses for the treatment of, two knee joint swelling, weak, pain disappear, squat down and other movable functions recover normal.Follow up a case by regular visits to and do not recur half a year.
Claims (2)
1. a Chinese medicine composition for the treatment of osteoarthritis, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Rehmanniae Preparata 10-40 part, Rhizoma Alismatis 5-25 part, Rhizoma Dioscoreae 10-40 part, Radix Aconiti Lateralis Preparata 5-20 part, Fructus Corni 10-40 part, Ramulus Cinnamomi 5-25 part, Semen Plantaginis 10-30 part, Radix Morindae Officinalis 5-20 part, Rhizoma Drynariae 5-25 part, Herba speranskiae tuberculatae 10-40 part, Herba Pyrolae 5-20 part, Radix Paeoniae Alba 10-40 part, Herba Saussureae Involueratae 10-30 part, Folium Et Cacumen Murrayae 10-40 part, Cortex Eucommiae 5-25 part, Rhizoma Homalomenae 5-25 part, Radix Gentianae Macrophyllae 5-20 part, Rhizoma Corydalis 10-30 part, Rhizoma Corydalis Decumbentis 5-25 part, Radix Angelicae Dahuricae 10-40 part, Caulis Sargentodoxae 5-25 part, Herba Siegesbeckiae 10-30 part, Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine composition for the treatment of osteoarthritis according to claim 1, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 30 parts of Radix Rehmanniae Preparata, 15 parts of Rhizoma Alismatis, 30 parts of Rhizoma Dioscoreaes, 10 parts of Radix Aconiti Lateralis Preparatas, 30 parts of Fructus Corni, 15 parts of Ramulus Cinnamomi, 20 parts of Semen Plantaginiss, 10 parts of Radix Morindae Officinaliss, 15 parts of Rhizoma Drynariae, 30 parts of Herba speranskiae tuberculataes, 10 parts of Herba Pyrolaes, 30 parts of the Radix Paeoniae Albas, 20 parts of Herba Saussureae Involuerataes, 30 parts of Folium Et Cacumen Murrayae, 15 parts of the Cortexs Eucommiae, 15 parts of Rhizoma Homalomenaes, 10 parts of Radix Gentianae Macrophyllae, 20 parts of Rhizoma Corydalis, 15 parts of Rhizoma Corydalis Decumbentiss, 30 parts of the Radixs Angelicae Dahuricae, 15 parts of Caulis Sargentodoxaes, 20 parts of Herba Siegesbeckiaes, 10 parts, Radix Glycyrrhizae.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105477226A (en) * | 2016-01-22 | 2016-04-13 | 王浩 | Traditional Chinese composition for treating osteoarthritis |
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| WO2005110431A1 (en) * | 2004-05-19 | 2005-11-24 | University Of Manitoba | Herbal product containing glucosamine |
| CN103520654A (en) * | 2013-10-25 | 2014-01-22 | 梁轶聪 | Chinese medicine composition for treating knee osteoarthritis and preparation method of Chinese medicine composition |
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