CN105663612A - Traditional Chinese medicine composition for treating ankylosing spondylitis - Google Patents

Traditional Chinese medicine composition for treating ankylosing spondylitis Download PDF

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CN105663612A
CN105663612A CN201610138214.4A CN201610138214A CN105663612A CN 105663612 A CN105663612 A CN 105663612A CN 201610138214 A CN201610138214 A CN 201610138214A CN 105663612 A CN105663612 A CN 105663612A
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herba
radix
chinese medicine
medicine composition
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孙胜波
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Abstract

The invention relates to a traditional Chinese medicine composition for treating ankylosing spondylitis.The traditional Chinese medicine composition is prepared from, by weight, 10-30 parts of radix morindae officinalis, 5-25 parts of spreading hedyotis herb, 5-20 parts of caulis sinomenii, 5-25 parts of rhizoma homalomenae, 5-25 parts of herba pyrolae, 5-25 parts of herb of speranskia tuberculata (Bunge)Baill., 5-25 parts of radix cudramiae, 5-25 parts of herba erodii seu geranii, 5-20 parts of herba aristolochiae mollissimae, 5-25 parts of willow branches, 5-25 parts of rhizoma curculiginis, 5-25 parts of semen allii tuberose, 5-20 parts of common threewingnut roots, 5-25 parts of radix zanthoxyli, 5-25 parts of glossy privet fruit, 5-25 parts of cortex acanthopanacis, 5-25 parts of root bark and bark of aralia elata (Miq.)Seem., 5-20 parts of root bark of ampelopsis humulifolia bunge, 5-25 parts of herba siegesbeckiae, 5-25 parts of roots and vines of schizophragma integrifolia (Franch.) Oliv., 5-25 parts of Chinese starjasmine stems and 5-15 parts of licorice roots.The traditional Chinese medicine composition has the effects of warming and tonifying the liver and kidney, strengthening the tendons and bones, promoting blood circulation to remove blood stasis, dispelling wind and eliminating dampness, relaxing the tendons and activating the collaterals and relieve pain and swelling and is significant in treatment effect and reliable in action when the traditional Chinese medicine composition is used for treating the ankylosing spondylitis.

Description

A kind of Chinese medicine composition treating ankylosing spondylitis
Technical field
The present invention relates to the pharmaceutical product not determining structure of a kind of traditional herbal medicines, especially a kind of Chinese medicine composition treating ankylosing spondylitis.
Background technology
Ankylosing spondylitis belongs to rheumatism category, the one of seronegative spondyloanthropathy. The chronic disease that this disease is is major lesions with spinal column, involves sacroiliac joint, causes rigid spine and fibrosis, cause in various degree eye, lung, muscle, skeleton pathological changes, belong to autoimmune disease. Be more common in 16-30 year between twenty and fifty, male is common, and 40 years old is rare with sequela person. Primary disease insidious onset, makes slow progress, and General Symptoms is lighter. Early stage, often to have back pain and morning to rise stiff, alleviates after activity, and can with low grade fever, weak, loss of appetite, the symptom such as become thin. During beginning, pain is intermittent, develops into persistence after several years several months, and later inflammatory pain disappears, and spinal column is from bottom to top partly or entirely tetanic, bow-backed deformity occurs. Female patient periarticular is by invading more typically, and progress is relatively slow, and deformity of spine is lighter. Modern medical therapy application nonsteroidal antiinflammatory drug and immune formulation even hormone, though can relief of symptoms, but long-term taking easily causes the side effect such as Gastric mucosal lesion, hepatorenal damage, bone marrow depression, and patient is often difficult to tolerate, after drug withdrawal easily repeatedly or symptom increase the weight of earlier above.
Motherland's medical science is thought that ankylosing spondylitis is many and is attacked by outside cold-damp, damp and hot contamination, traumatic injury, obstruction of collaterals by blood stasis, and QI-blood circulation is smooth, or natural endowment is not enough, deficiency of kidney-essence, caused by the mistake of bone arteries and veins is supported.
According to theory of Chinese medical science, for the pathogeny of ankylosing spondylitis, adopt the method for the treatment of of temperature compensation Liver and kidney, bone and muscle strengthening, blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, alleviating pain and detumescence, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Treating in prior art after ankylosing spondylitis exists drug withdrawal easily repeatedly or the deficiency that increases the weight of earlier above of symptom to overcome, the present invention provides and a kind of prepares simplicity, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of knee osteoarthritis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition treating ankylosing spondylitis, it is characterized in that: its raw material of Chinese medicine and weight be: Radix Morindae Officinalis 10-30 part, Herba Hedyotidis Diffusae 5-25 part, Caulis Sinomenii 5-20 part, Rhizoma Homalomenae 5-25 part, Herba Pyrolae 5-25 part, Herba speranskiae tuberculatae 5-25 part, Radix Cudraniae 5-25 part, Herba Erodii 5-25 part, Herba Aristolochiae Mollissimae 5-20 part, Ramulus Salicis Babylonicae 5-25 part, Rhizoma Curculiginis 5-25 part, Semen Allii Tuberosi 5-25 part, Radix Tripterygii Wilfordii 5-20 part, Radix Zanthoxyli 5-25 part, Fructus Ligustri Lucidi 5-25 part, Cortex Acanthopancis 5-25 part, thorn fossilia dentis mastodi 5-25 part, heptangle Radix Ampelopsis 5-20 part, Herba Siegesbeckiae 5-25 part, Cortex schizophragmatis integrifolii radicis 5-25 part, Caulis Trachelospermi 5-25 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition treating ankylosing spondylitis, it is characterized in that: its raw material of Chinese medicine and weight be: Radix Morindae Officinalis 20 parts, Herba Hedyotidis Diffusae 15 parts, Caulis Sinomenii 10 parts, Rhizoma Homalomenae 15 parts, Herba Pyrolae 15 parts, Herba speranskiae tuberculatae 15 parts, Radix Cudraniae 15 parts, Herba Erodii 15 parts, Herba Aristolochiae Mollissimae 10 parts, Ramulus Salicis Babylonicae 15 parts, Rhizoma Curculiginis 15 parts, Semen Allii Tuberosi 15 parts, Radix Tripterygii Wilfordii 10 parts, Radix Zanthoxyli 15 parts, Fructus Ligustri Lucidi 15 parts, Cortex Acanthopancis 15 parts, thorn fossilia dentis mastodi 15 parts, heptangle Radix Ampelopsis 10 parts, Herba Siegesbeckiae 15 parts, Cortex schizophragmatis integrifolii radicis 15 parts, Caulis Trachelospermi 15 parts, 10 parts of Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription. In Chinese medicine composition of the present invention: Radix Morindae Officinalis has effect of reinforcing the kidney and supporting YANG, bone and muscle strengthening, expelling wind and removing dampness; Herba Hedyotidis Diffusae has effect of heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain; Caulis Sinomenii has effect of wind-damp dispelling, the meridian dredging, diuresis; Rhizoma Homalomenae has effect of wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, alleviating pain and detumescence; Herba Pyrolae has the kidney invigorating bone strengthening、Expelling wind and removing dampness、Cough-relieving、Effect of hemostasis; Herba speranskiae tuberculatae has expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation and stopping pain, solution poison effect of rash; Radix Cudraniae has effect of dispelling wind and removing obstruction in the collateral, removing damp-heat, removing toxic substances and promoting subsidence of swelling; Herba Erodii has effect of wind-damp dispelling, the meridian dredging, antidiarrheal dysentery; Herba Aristolochiae Mollissimae has expelling wind and removing dampness、Promoting blood circulation to remove obstruction in the collateral、Effect of pain relieving; Ramulus Salicis Babylonicae has effect of expelling wind and removing dampness, removing toxic substances and promoting subsidence of swelling; Rhizoma Curculiginis has effect of reinforcing the kidney and supporting YANG, benefiting essence-blood, bone and muscle strengthening, promoting the circulation of blood detumescence; Semen Allii Tuberosi has effect of temperature compensation Liver and kidney, tonifying YANG controlling nocturnal emission with astringent drugs; Radix Tripterygii Wilfordii has expelling wind and removing dampness、Removing obstruction in the collateral to relieve pain、Promoting blood circulation and detumescence、Effect of parasite killing removing toxic substances; Radix Zanthoxyli has effect of promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral; Effect that Fructus Ligustri Lucidi has nourishing the liver and kidney, tonifying YIN nourishes blood; Cortex Acanthopancis has effect of wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening; Thorn fossilia dentis mastodi has vital energy benefiting and the kidney invigorating、Expelling wind and removing dampness、Effect of promoting blood circulation and stopping pain; Heptangle Radix Ampelopsis has promoting blood circulation to remove blood stasis, eliminating inflammation and expelling toxin, granulation promoting long bone, effect except wind damp eliminating; Herba Siegesbeckiae has effect of expelling wind and removing dampness, dredge the meridian passage, heat-clearing and toxic substances removing; Cortex schizophragmatis integrifolii radicis has effect of relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and activating blood circulation; Caulis Trachelospermi has dispelling wind and removing obstruction in the collateral、Effect of removing heat from blood detumescence; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription. The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, help using assistant mutually, play effect of temperature compensation Liver and kidney, bone and muscle strengthening, blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, alleviating pain and detumescence altogether, the treatment of ankylosing spondylitis is reached treating both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and preparation is easy, medicine source is wide, cost is low for it. The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose. Verifying by clinic application, it is evident in efficacy reliably, mild in medicine property and, do not occur that toxic and side effects, effective percentage reach 96%, cure rate 72%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
A kind of Chinese medicine composition treating ankylosing spondylitis, its raw material of Chinese medicine and weight proportion be: Radix Morindae Officinalis 20g, Herba Hedyotidis Diffusae 15g, Caulis Sinomenii 10g, Rhizoma Homalomenae 15g, Herba Pyrolae 15g, Herba speranskiae tuberculatae 15g, Radix Cudraniae 15g, Herba Erodii 15g, Herba Aristolochiae Mollissimae 10g, Ramulus Salicis Babylonicae 15g, Rhizoma Curculiginis 15g, Semen Allii Tuberosi 15g, Radix Tripterygii Wilfordii 10g, Radix Zanthoxyli 15g, Fructus Ligustri Lucidi 15g, Cortex Acanthopancis 15g, thorn fossilia dentis mastodi 15g, heptangle Radix Ampelopsis 10g, Herba Siegesbeckiae 15g, Cortex schizophragmatis integrifolii radicis 15g, Caulis Trachelospermi 15g, Radix Glycyrrhizae 10g.
Embodiment 2
A kind of Chinese medicine composition treating ankylosing spondylitis, its raw material of Chinese medicine and weight proportion be: Radix Morindae Officinalis 15g, Herba Hedyotidis Diffusae 25g, Caulis Sinomenii 5g, Rhizoma Homalomenae 20g, Herba Pyrolae 10g, Herba speranskiae tuberculatae 25g, Radix Cudraniae 5g, Herba Erodii 20g, Herba Aristolochiae Mollissimae 12g, Ramulus Salicis Babylonicae 25g, Rhizoma Curculiginis 5g, Semen Allii Tuberosi 20g, Radix Tripterygii Wilfordii 12g, Radix Zanthoxyli 25g, Fructus Ligustri Lucidi 5g, Cortex Acanthopancis 20g, thorn fossilia dentis mastodi 10g, heptangle Radix Ampelopsis 15g, Herba Siegesbeckiae 5g, Cortex schizophragmatis integrifolii radicis 20g, Caulis Trachelospermi 10g, Radix Glycyrrhizae 15g.
Embodiment 3
A kind of Chinese medicine composition treating ankylosing spondylitis, its raw material of Chinese medicine and weight proportion be: Radix Morindae Officinalis 25g, Herba Hedyotidis Diffusae 5g, Caulis Sinomenii 15g, Rhizoma Homalomenae 10g, Herba Pyrolae 20g, Herba speranskiae tuberculatae 5g, Radix Cudraniae 25g, Herba Erodii 10g, Herba Aristolochiae Mollissimae 20g, Ramulus Salicis Babylonicae 5g, Rhizoma Curculiginis 25g, Semen Allii Tuberosi 10g, Radix Tripterygii Wilfordii 20g, Radix Zanthoxyli 5g, Fructus Ligustri Lucidi 25g, Cortex Acanthopancis 12g, thorn fossilia dentis mastodi 20g, heptangle Radix Ampelopsis 5g, Herba Siegesbeckiae 25g, Cortex schizophragmatis integrifolii radicis 10g, Caulis Trachelospermi 20g, Radix Glycyrrhizae 5g.
Embodiment 4
A kind of Chinese medicine composition treating ankylosing spondylitis, its raw material of Chinese medicine and weight proportion be: Radix Morindae Officinalis 10g, Herba Hedyotidis Diffusae 20g, Caulis Sinomenii 12g, Rhizoma Homalomenae 25g, Herba Pyrolae 5g, Herba speranskiae tuberculatae 20g, Radix Cudraniae 10g, Herba Erodii 25g, Herba Aristolochiae Mollissimae 5g, Ramulus Salicis Babylonicae 20g, Rhizoma Curculiginis 10g, Semen Allii Tuberosi 25g, Radix Tripterygii Wilfordii 5g, Radix Zanthoxyli 20g, Fructus Ligustri Lucidi 10g, Cortex Acanthopancis 25g, thorn fossilia dentis mastodi 5g, heptangle Radix Ampelopsis 20g, Herba Siegesbeckiae 12g, Cortex schizophragmatis integrifolii radicis 25g, Caulis Trachelospermi 5g, Radix Glycyrrhizae 8g.
Embodiment 5
A kind of Chinese medicine composition treating ankylosing spondylitis, its raw material of Chinese medicine and weight proportion be: Radix Morindae Officinalis 30g, Herba Hedyotidis Diffusae 10g, Caulis Sinomenii 20g, Rhizoma Homalomenae 5g, Herba Pyrolae 25g, Herba speranskiae tuberculatae 10g, Radix Cudraniae 20g, Herba Erodii 5g, Herba Aristolochiae Mollissimae 15g, Ramulus Salicis Babylonicae 10g, Rhizoma Curculiginis 20g, Semen Allii Tuberosi 5g, Radix Tripterygii Wilfordii 15g, Radix Zanthoxyli 10g, Fructus Ligustri Lucidi 20g, Cortex Acanthopancis 10g, thorn fossilia dentis mastodi 25g, heptangle Radix Ampelopsis 12g, Herba Siegesbeckiae 20g, Cortex schizophragmatis integrifolii radicis 5g, Caulis Trachelospermi 25g, Radix Glycyrrhizae 12g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament. Concrete grammar is as follows: put in container by the raw material of Chinese medicine of prescription, adds cold water and covers powder, soak 15～20 minutes, adds water and do not have powder about 6 centimetres, carries out first time decoction, adopts intense fire to decoct before at a simmer, with slow fire boiling 20～30 minutes after boiling; Second time decocts, and adds water and did not have powder about 4 centimetres, and water decocts 15～20 minutes after boiling. Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition treating ankylosing spondylitis given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 50 example, male 31 examples, female 19 example, 15～45 years old age.
Two, diagnostic criteria:
(1) symptom: with two sacroiliac jointes, lower back pain repeatedly is main;
(2) sign: early, mid-term patient spine movable function limited in various degree, patients with terminal spinal column occurs that hunchback is fixing, and thorax activity reduces or disappears;
(3) lab testing: erythrocyte sedimentation rate speeds more, how negative rheumatoid factor is, HLA-B27 strong positive;
(4) x-ray inspection: there is the typical consequence of ankylosing spondylitis and sacroiliitis.
Three, usage and dosage: during clinical practice, potion on the one, twice extracting juice of decocting is about 400ml, point morning, late twice empty stomach decoction being taken warmly. It within six days, it is a course for the treatment of. Avoid cold and uncooked food during treatment the thing of pungent stimulation.
Four, criterion of therapeutical effect:
1, curing: heavy stiff transference cure, sacroiliac joint and each symptoms of joint pain disappear, and arthroncus disappears, and joint motion is freely;Each joint positive sign disappears, and each joint physiological function recovers normal;
2, effective: heavy stiff symptom is clearly better, and sacroiliac joint and each symptoms of joint pain are clearly better, and arthroncus is clearly better, and joint motion is obviously improved; Each joint positive sign is clearly better, and each function of joint is substantially recovered;
3 is effective: heavy stiff symptom takes a turn for the better, and sacroiliac joint and each symptoms of joint pain take a turn for the better, and arthroncus takes a turn for the better, and joint motion improves; Each joint positive sign alleviates, and each function of joint has improvement;
4, invalid: heavy stiff symptom is without improvement, sacroiliac joint and each symptoms of joint pain without improvement, and arthroncus is unchanged; Each joint positive sign is without improvement, and each function of joint is unchanged.
Five, therapeutic effect: in this clinical observation case, take medicine 2-5 the course for the treatment of, 36 examples of fully recovering, follow up a case by regular visits to and have no recurrence; Effective 7 examples, effective 5 examples, invalid 2 examples. Toxic and side effects is there is not during treatment.
Six, model case:
Case 1:
Feng, man, 29 years old. Private prosecution lumbosacral deadlock pain is more than 1 year, the double; two knee joint of companion, capped elbow pain, can not squat down, dysstasia, bend over to stand up limitation of activity, walk difficult. Examining and see: the tetanic shape of spinal column, light red tongue, tongue are thick greasy in vain, stringy and hesitant pulse. X-ray shows: sacral joint is broadening. Diagnosis is: ankylosing spondylitis. Taking 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom substantially alleviates, and can walk and stand; Continuing to take 2 courses for the treatment of, symptom is wholly absent, and functional rehabilitation is normal, recovery from illness. Follow up a case by regular visits to after half a year without recurrence.
Case 2:
Huang, female, 43 years old. Main suit: waist, the back of the body, neck, double; two hip more than 2 years of multi-joint pain, bow-backed deformity, cervical vertebra, lumbar vertebra are stiff tetanic, limitation of activity, stand up difficulty night, and both legs joint is aching and tired weak, take a turn for the better after playing activity morning. Diagnosis is: ankylosing spondylitis. Taking 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, waist, neck, hip pain substantially alleviate; Continuing to take 2 courses for the treatment of, symptoms of joint pain disappears, recovery from illness. Follow up a case by regular visits to 1 year and do not recur.

Claims (2)

1. the Chinese medicine composition treating ankylosing spondylitis, it is characterized in that: its raw material of Chinese medicine and weight be: Radix Morindae Officinalis 10-30 part, Herba Hedyotidis Diffusae 5-25 part, Caulis Sinomenii 5-20 part, Rhizoma Homalomenae 5-25 part, Herba Pyrolae 5-25 part, Herba speranskiae tuberculatae 5-25 part, Radix Cudraniae 5-25 part, Herba Erodii 5-25 part, Herba Aristolochiae Mollissimae 5-20 part, Ramulus Salicis Babylonicae 5-25 part, Rhizoma Curculiginis 5-25 part, Semen Allii Tuberosi 5-25 part, Radix Tripterygii Wilfordii 5-20 part, Radix Zanthoxyli 5-25 part, Fructus Ligustri Lucidi 5-25 part, Cortex Acanthopancis 5-25 part, thorn fossilia dentis mastodi 5-25 part, heptangle Radix Ampelopsis 5-20 part, Herba Siegesbeckiae 5-25 part, Cortex schizophragmatis integrifolii radicis 5-25 part, Caulis Trachelospermi 5-25 part, Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine composition treating ankylosing spondylitis according to claim 1, it is characterized in that: its raw material of Chinese medicine and weight be: Radix Morindae Officinalis 20 parts, Herba Hedyotidis Diffusae 15 parts, Caulis Sinomenii 10 parts, Rhizoma Homalomenae 15 parts, Herba Pyrolae 15 parts, Herba speranskiae tuberculatae 15 parts, Radix Cudraniae 15 parts, Herba Erodii 15 parts, Herba Aristolochiae Mollissimae 10 parts, Ramulus Salicis Babylonicae 15 parts, Rhizoma Curculiginis 15 parts, Semen Allii Tuberosi 15 parts, Radix Tripterygii Wilfordii 10 parts, Radix Zanthoxyli 15 parts, Fructus Ligustri Lucidi 15 parts, Cortex Acanthopancis 15 parts, thorn fossilia dentis mastodi 15 parts, heptangle Radix Ampelopsis 10 parts, Herba Siegesbeckiae 15 parts, Cortex schizophragmatis integrifolii radicis 15 parts, Caulis Trachelospermi 15 parts, 10 parts of Radix Glycyrrhizae.
CN201610138214.4A 2016-03-11 2016-03-11 Traditional Chinese medicine composition for treating ankylosing spondylitis Pending CN105663612A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114533695A (en) * 2022-03-15 2022-05-27 佛山市第五人民医院（佛山市干部疗养院、佛山市工伤康复中心） An oral Chinese medicinal composition for treating ankylosing spondylitis and its preparation method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114533695A (en) * 2022-03-15 2022-05-27 佛山市第五人民医院（佛山市干部疗养院、佛山市工伤康复中心） An oral Chinese medicinal composition for treating ankylosing spondylitis and its preparation method

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Application publication date: 20160615