CN103191383A - Traditional Chinese medicine composition for treating rheumatoid arthritis - Google Patents

Traditional Chinese medicine composition for treating rheumatoid arthritis Download PDF

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CN103191383A
CN103191383A CN2013101037899A CN201310103789A CN103191383A CN 103191383 A CN103191383 A CN 103191383A CN 2013101037899 A CN2013101037899 A CN 2013101037899A CN 201310103789 A CN201310103789 A CN 201310103789A CN 103191383 A CN103191383 A CN 103191383A
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radix
rhizoma
chinese medicine
rheumatoid arthritis
root
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CN103191383B (en
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黄相杰
毕晓英
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Abstract

The invention relates to a traditional Chinese medicine composition for treating rheumatoid arthritis. The composition comprises the following traditional Chinese medicine raw materials by weight: 20-30g of gypsum, 15-20g of common anemarrhena rhizome, 10-15g of cassia twig, 10-15g of white paeony root, 12-15g of divaricate saposhnikovia root, 25-30g of honeysuckle stem, 40-50g of radix rehmanniae, 18-25g of Chinese clematis root, 15-20g of incised notopterygium rhizome and root, 10-15g of doubleteeth pubescent angelica root, 6-9g of mint, 10-15g of cicada slough, 25-30g of orientvine vine, 30-35g of radix astragali, 25-30g of salvia miltiorrhiza, 15-20g of largehead atractylodes rhizome, 10-15g of honeysuckle, 15-20g of Chinese angelica, 10-15g of cibot rhizome, 6-9g of dried ginger, 12-15g of paniculate swallowwort root, 12-15g of monkshood, 10-15g of Indian bread and 3-6g of liquorice. The composition has the beneficial effects that through dialectical compatibility, the medicine components in the composition supplement each other in actions, have synergistic action and jointly achieve the functions of invigorating the spleen and benefiting qi, tonifying the liver and benefiting the kidney, promoting blood circulation to remove meridian obstruction, clearing away heat and toxic materials and eliminating dampness to remove wind, thus achieving the aim of treating rheumatoid arthritis; and the composition is wide in medicine sources of the components, is simple and convenient to prepare and has mild medicine properties and no toxic or side effects.

Description

A kind of Chinese medicine composition for the treatment of rheumatoid arthritis
Technical field:
The present invention relates to a kind of field of Chinese medicines, specifically a kind of Chinese medicine composition for the treatment of rheumatoid arthritis.
Background technology:
Rheumatoid arthritis is the chronic systemic inflammatory disease that a kind of cause of disease is not understood as yet, is main clinical manifestation with pathological changes outside chronic, symmetry, many synovial jointss inflammation and the joint, belongs to the autoimmune inflammatory diseases.Modern medicine thinks that rheumatoid arthritis is one and the closely-related diseases of factor such as environment, cell, virus, heredity, gonadal hormone and the neural mental status.This disease is sent out well in little joints such as hands, wrist, foots, and outbreak is symmetrical distribution repeatedly.Main clinical manifestation is arthropathy, and arthrosis is symmetry often, involves little joint, and is the most common with the multitudinous toe joint of the proximal interphalangeal joint of hands, carpal joint, foot, seriously involves big joint and ridge joints such as elbow, shoulder ankle, knee joint.End-stage patients are mainly joint dislocation, subluxation, deformity change, movable serious hindrance, and patient can't take care of oneself.Therefore, patient with rheumatoid arthritis should in time be treated.
At present, the clinical treatment method has multiple: the one, and the pain relieving western medicine.Can only pain relieving, can not control pain, take easy generation dependency and toxic and side effects for a long time.The 2nd, comprise the naturopathy of electrotherapy, infrared ray radiation, thermotherapy.Can not effect a radical cure, can only benumb neural lenitive symptom.The 3rd, massage acupuncture and moxibustion therapy.Based on alleviation patient's clinical symptoms, but not the radical cure means.The 4th, block therapy.Local anesthesia is with temporary transient pain relieving, and drug effect symptom later returns.The 5th, operative treatment.The patient who is fit to operation is few, and the expense height, wound is big, convalescent period is long, easily recur.
The traditional Chinese medical science is thought the generation of rheumatoid arthritis, and it is low that it causes immunity of organisms mainly due to reasons (endogenous cause of ill, exopathogenic factor) such as fatigue, wound, infection, with weakened body resistance, heresy is invaded and the turbid congestion of expectorant is relevant.Function is lost empty, and wind, cold, damp gas are invaded body in an opponent's defence and stagnated joint, meridians and cause.Because of kidney governing bones spermatogenesis, foster marrow.As deficiency of kidney-QI, can not main bone, just bone diseases can appear in foster marrow; Liver main warp network, domination whole body ligament and joint motions are as excessive rising of liver-YANG, just deficiency of liver-blood twitching pain of muscle, numbness can occur, bend and stretch difficulty, even symptoms such as arthroncus, scorching hot, deformity; The spleen has the function to transport and transform nutrients, and main muscle if spleen loses fortuneization, can not nourish skin and the atrophy of aching of muscle joint tissue then can occur.
According to theory of Chinese medical science, at the pathogeny of rheumatoid arthritis, serve as the total method for the treatment of to regulate vital organs of the human body function, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention:
The present invention is in order to overcome the deficiencies in the prior art, provides that a kind of preparation is easy, the medicine source is wide, cost is low, good effect, the Chinese medicine composition of the treatment rheumatoid arthritis that toxic and side effects is little.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis is characterized in that being made up of following Chinese medicine raw materials by weight proportion: Gypsum Fibrosum 20-30g, Rhizoma Anemarrhenae 15-20g, Ramulus Cinnamomi 10-15g, Radix Paeoniae Alba 10-15g, Radix Saposhnikoviae 12-15g, Caulis Lonicerae 25-30g, Radix Rehmanniae 40-50g, Radix Clematidis 18-25g, Rhizoma Et Radix Notopterygii 15-20g, Radix Angelicae Pubescentis 10-15g, Herba Menthae 6-9g, Periostracum Cicadae 10-15g, Caulis Sinomenii 25-30g, Radix Astragali 30-35g, Radix Salviae Miltiorrhizae 25-30g, Rhizoma Atractylodis Macrocephalae 15-20g, Flos Lonicerae 10-15g, Radix Angelicae Sinensis 15-20g, Rhizoma Cibotii 10-15g, Rhizoma Zingiberis 6-9g, Radix Cynanchi Paniculati 12-15g, Radix Aconiti Lateralis Preparata 12-15g, Poria 10-15g, Radix Glycyrrhizae 3-6g.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis is characterized in that being made up of following Chinese medicine raw materials by weight proportion: Gypsum Fibrosum 30g, Rhizoma Anemarrhenae 15g, Ramulus Cinnamomi 15g, Radix Paeoniae Alba 15g, Radix Saposhnikoviae 12g, Caulis Lonicerae 30g, Radix Rehmanniae 50g, Radix Clematidis 18g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, Herba Menthae 9g, Periostracum Cicadae 10g, Caulis Sinomenii 30g, Radix Astragali 30g, Radix Salviae Miltiorrhizae 30g, Rhizoma Atractylodis Macrocephalae 15g, Flos Lonicerae 15g, Radix Angelicae Sinensis 15g, Rhizoma Cibotii 15g, Rhizoma Zingiberis 9g, Radix Cynanchi Paniculati 15g, Radix Aconiti Lateralis Preparata 12g, Poria 15g, Radix Glycyrrhizae 6g.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In the present invention in the drug composition: Gypsum Fibrosum has the effect that clearing away heat-fire, relieving restlessness quench the thirst; The Rhizoma Anemarrhenae Rhizoma Anemarrhenae has clearing away heat-fire, the effect of promoting the production of body fluid and moisturizing; Ramulus Cinnamomi has the effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; The Radix Paeoniae Alba has the effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Radix Saposhnikoviae has the effect that expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion are jerked surely; Caulis Lonicerae has heat-clearing and toxic substances removing, dispelling wind collateral dredging effect; The Radix Rehmanniae has the effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, pain relieving regulating menstruation; Radix Clematidis has the effect of expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the hypochondriac lump of loosing; Rhizoma Et Radix Notopterygii has the effect of diffusing exterior cold, wind-damp dispelling, sharp joint, pain relieving; Radix Angelicae Pubescentis has the effect of expelling wind and dampness, dispersing cold for relieving pain; Herba Menthae has the effect of dispelling wind and heat pathogens, clear sharp detoxifcation, dispersing the stagnated live-QI to relieve the stagnation of QI; The effect that Periostracum Cicadae has dispelling wind-heat, rash sore-throat relieving, removing nebula to improve visual acuity, expellings wind and relieving convulsion.Caulis Sinomenii has wind-damp dispelling, the meridian dredging, the effect of diuresis; The Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating take off admittedly, the effect of wind dispelling fortune poison; Radix Salviae Miltiorrhizae has the effect of promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, the antiabortive effect of hidroschesis; Flos Lonicerae has the effect of heat-clearing and toxic substances removing; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation; Rhizoma Cibotii has the effect in invigorating the liver and kidney, strong spinal column, wind-damp dispelling, sharp joint; Rhizoma Zingiberis has that warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, the dampness expectorant, the effect of warming the lung to resolve fluid-retention; Radix Cynanchi Paniculati has the effect of analgesia, cough-relieving, inducing diuresis to remove edema, promoting blood circulation and detoxication; Radix Aconiti Lateralis Preparata has recuperating depleted YANG and rescuing the patient from collapse, mends effect fiery supporing yang, dispersing cold for relieving pain; Poria has the effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, plays invigorating the spleen and benefiting QI, the liver and the kidney tonifying, promoting blood circulation to remove obstruction in the collateral, heat-clearing and toxic substances removing, dampness altogether and goes the effect of wind, thereby reach the purpose for the treatment of rheumatoid arthritis.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, the medicine source is wide, cost is low.It follows the prescription principle of medication of the traditional Chinese medical science, and various component drug adopt the usefulness that is decocted in water for oral dose.Through the clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, has no side effect, and total effective rate reaches 94.8%, and cure rate reaches 36.5%.
The specific embodiment
Embodiment 1: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, and it is made up of following Chinese medicine raw materials by weight proportion: Gypsum Fibrosum 20-30g, Rhizoma Anemarrhenae 15-20g, Ramulus Cinnamomi 10-15g, Radix Paeoniae Alba 10-15g, Radix Saposhnikoviae 12-15g, Caulis Lonicerae 25-30g, Radix Rehmanniae 40-50g, Radix Clematidis 18-25g, Rhizoma Et Radix Notopterygii 15-20g, Radix Angelicae Pubescentis 10-15g, Herba Menthae 6-9g, Periostracum Cicadae 10-15g, Caulis Sinomenii 25-30g, Radix Astragali 30-35g, Radix Salviae Miltiorrhizae 25-30g, Rhizoma Atractylodis Macrocephalae 15-20g, Flos Lonicerae 10-15g, Radix Angelicae Sinensis 15-20g, Rhizoma Cibotii 10-15g, Rhizoma Zingiberis 6-9g, Radix Cynanchi Paniculati 12-15g, Radix Aconiti Lateralis Preparata 12-15g, Poria 10-15g, Radix Glycyrrhizae 3-6g.
Chinese medicine composition of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soaked 20~30 minutes, add water again and do not have about 8 centimetres of powder, decoct.Adopt intense fire to decoct earlier, the back of boiling takes concoction with slow fire boiling 20~30 minutes; Add water and carry out decocting the second time again, decoction took concoction in 15~20 minutes after water boiled.Twice decoction removed slag and merged behind the extracting juice.
Embodiment 2: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, its raw material of Chinese medicine by following weight is formed: Gypsum Fibrosum 30g, Rhizoma Anemarrhenae 15g, Ramulus Cinnamomi 15g, Radix Paeoniae Alba 15g, Radix Saposhnikoviae 12g, Caulis Lonicerae 30g, Radix Rehmanniae 50g, Radix Clematidis 18g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, Herba Menthae 9g, Periostracum Cicadae 10g, Caulis Sinomenii 30g, Radix Astragali 30g, Radix Salviae Miltiorrhizae 30g, Rhizoma Atractylodis Macrocephalae 15g, Flos Lonicerae 15g, Radix Angelicae Sinensis 15g, Rhizoma Cibotii 15g, Rhizoma Zingiberis 9g, Radix Cynanchi Paniculati 15g, Radix Aconiti Lateralis Preparata 12g, Poria 15g, Radix Glycyrrhizae 6g.
Embodiment 3: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, its raw material of Chinese medicine by following weight is formed: Gypsum Fibrosum 20g, Rhizoma Anemarrhenae 20g, Ramulus Cinnamomi 10g, Radix Paeoniae Alba 10g, Radix Saposhnikoviae 15g, Caulis Lonicerae 25g, Radix Rehmanniae 40g, Radix Clematidis 25g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 10g, Herba Menthae 6g, Periostracum Cicadae 15g, Caulis Sinomenii 25g, Radix Astragali 35g, Radix Salviae Miltiorrhizae 25g, Rhizoma Atractylodis Macrocephalae 20g, Flos Lonicerae 10g, Radix Angelicae Sinensis 20g, Rhizoma Cibotii 10g, Rhizoma Zingiberis 6g, Radix Cynanchi Paniculati 12g, Radix Aconiti Lateralis Preparata 15g, Poria 10g, Radix Glycyrrhizae 3g.
Embodiment 3: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, its raw material of Chinese medicine by following weight is formed: Gypsum Fibrosum 25g, Rhizoma Anemarrhenae 18g, Ramulus Cinnamomi 13g, Radix Paeoniae Alba 12g, Radix Saposhnikoviae 14g, Caulis Lonicerae 28g, Radix Rehmanniae 45g, Radix Clematidis 20g, Rhizoma Et Radix Notopterygii 16g, Radix Angelicae Pubescentis 12g, Herba Menthae 8g, Periostracum Cicadae 13g, Caulis Sinomenii 26g, Radix Astragali 32g, Radix Salviae Miltiorrhizae 29g, Rhizoma Atractylodis Macrocephalae 19g, Flos Lonicerae 13g, Radix Angelicae Sinensis 18g, Rhizoma Cibotii 12g, Rhizoma Zingiberis 8g, Radix Cynanchi Paniculati 14g, Radix Aconiti Lateralis Preparata 13g, Poria 12g, Radix Glycyrrhizae 5g.
A kind of Chinese medicine composition for the treatment of rheumatoid arthritis, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is used for many years clinically, clinical observation case 96 examples, and male 33 examples, women 63 examples, at 30~75 years old age, the course of disease all reached more than 6 weeks.
Two, usage and dosage: during clinical practice, the component in the compositions, consumption are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.Potion on the one, the about 450ml of twice extracting juice of decocting divides and takes for early, middle and late three times.15 is a course for the treatment of.
Three, criterion of therapeutical effect:
(1) clinical cure: symptom, sign disappear, and it is normal that functional activity recovers, and the laboratory leading indicator is recovered or approached normal;
(2) produce effects: symptom, sign disappear substantially, and function of joint is recovered substantially, can participate in operate as normal, and the laboratory leading indicator is obviously improved, decline degree 〉=50%;
(3) effective: symptom, sign alleviate, and life can take care of oneself.The laboratory leading indicator also has improvement;
(4) invalid: symptom, sign and laboratory leading indicator do not have improvement.
Four, therapeutic effect: in the clinical observation case, take medicine 2-10 the course for the treatment of 35 examples of fully recovering, produce effects 45 examples, effective 11 examples, invalid 5 examples.Toxic and side effects does not take place during the treatment.
Five, model case:
1, Hu, the man, 42 years old, have earlier several thoughtful some months lassitude and weak, lose weight, symptom such as anorexia, the left gonalgia subsequently.Be rheumatoid arthritis through hospital diagnosis.Take 2 courses for the treatment of of medicament of Chinese medicine composition preparation of the present invention, pain symptom alleviates, and other symptoms are clearly better; Continue and obey 4 courses for the treatment of, pain symptom disappears, the movable recovery normally.
2, Qi, the woman, 46 years old, do not have obvious inducement and occur that the both hands palms refers to, interphalangeal joint swells and ache, joint stuffiness, the state of an illness increases the weight of gradually, and extremity many places arthralgia occurs, and limitation of movement is rheumatic arthritis through hospital diagnosis.Take 3 courses for the treatment of of medicament of Chinese medicine composition preparation of the present invention, each arthralgia of extremity obviously alleviates, and can walk with descending; Continue and obey 2 courses for the treatment of, pain symptom disappears substantially, and function of joint is recovered substantially.
3, permitted certain, man, 55 years old, whole body arthralgia and engender that the right hand four refers to and the left index finger swollen joints before this, can not stretch, the equal swelling of wrist and ankle joint, it is limited that right shoulder is gone up act, lumbago, difficulty in walking, simultaneously with symptoms such as dizziness and blurred vision, the unusual pain in joint when cloudy day and moral replace.Be rheumatic arthritis through hospital diagnosis.Take 2 courses for the treatment of of medicament of Chinese medicine composition preparation of the present invention, all symptoms make moderate progress; 2 courses for the treatment of of continuous clothes, the complete obiteration of swelling and ache of articulations digitorum manus, ankle joint can be walked as the normal person.

Claims (2)

1. a Chinese medicine composition for the treatment of rheumatoid arthritis is characterized in that being made up of following Chinese medicine raw materials by weight proportion: Gypsum Fibrosum 20-30g, Rhizoma Anemarrhenae 15-20g, Ramulus Cinnamomi 10-15g, Radix Paeoniae Alba 10-15g, Radix Saposhnikoviae 12-15g, Caulis Lonicerae 25-30g, Radix Rehmanniae 40-50g, Radix Clematidis 18-25g, Rhizoma Et Radix Notopterygii 15-20g, Radix Angelicae Pubescentis 10-15g, Herba Menthae 6-9g, Periostracum Cicadae 10-15g, Caulis Sinomenii 25-30g, Radix Astragali 30-35g, Radix Salviae Miltiorrhizae 25-30g, Rhizoma Atractylodis Macrocephalae 15-20g, Flos Lonicerae 10-15g, Radix Angelicae Sinensis 15-20g, Rhizoma Cibotii 10-15g, Rhizoma Zingiberis 6-9g, Radix Cynanchi Paniculati 12-15g, Radix Aconiti Lateralis Preparata 12-15g, Poria 10-15g, Radix Glycyrrhizae 3-6g.
2. a kind of Chinese medicine composition for the treatment of rheumatoid arthritis according to claim 1 is characterized in that being made up of following Chinese medicine raw materials by weight proportion: Gypsum Fibrosum 30g, Rhizoma Anemarrhenae 15g, Ramulus Cinnamomi 15g, Radix Paeoniae Alba 15g, Radix Saposhnikoviae 12g, Caulis Lonicerae 30g, Radix Rehmanniae 50g, Radix Clematidis 18g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, Herba Menthae 9g, Periostracum Cicadae 10g, Caulis Sinomenii 30g, Radix Astragali 30g, Radix Salviae Miltiorrhizae 30g, Rhizoma Atractylodis Macrocephalae 15g, Flos Lonicerae 15g, Radix Angelicae Sinensis 15g, Rhizoma Cibotii 15g, Rhizoma Zingiberis 9g, Radix Cynanchi Paniculati 15g, Radix Aconiti Lateralis Preparata 12g, Poria 15g, Radix Glycyrrhizae 6g.
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CN103656216A (en) * 2013-12-12 2014-03-26 黄根强 Traditional Chinese medicine for treating rheumatoid arthritis
CN104147163A (en) * 2014-08-04 2014-11-19 郭志文 Externally-used traditional Chinese medicine preparation for treating rheumatoid arthritis and preparation method thereof
CN104382992A (en) * 2014-11-13 2015-03-04 邹士东 Pharmaceutical composition for treating rheumatoid arthritis
CN104547670A (en) * 2014-12-22 2015-04-29 郑贺 Traditional Chinese medicine for treating arthritis
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CN106955327A (en) * 2015-12-01 2017-07-18 徐腾 A kind of Chinese medicine composition and compounding method for treating osteoarthropathy
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103656216A (en) * 2013-12-12 2014-03-26 黄根强 Traditional Chinese medicine for treating rheumatoid arthritis
CN104147163A (en) * 2014-08-04 2014-11-19 郭志文 Externally-used traditional Chinese medicine preparation for treating rheumatoid arthritis and preparation method thereof
CN104382992A (en) * 2014-11-13 2015-03-04 邹士东 Pharmaceutical composition for treating rheumatoid arthritis
CN104547670A (en) * 2014-12-22 2015-04-29 郑贺 Traditional Chinese medicine for treating arthritis
CN104825751A (en) * 2015-02-26 2015-08-12 龚正丰 Medicine composition for treating ankylosing spondylitis
CN106955327A (en) * 2015-12-01 2017-07-18 徐腾 A kind of Chinese medicine composition and compounding method for treating osteoarthropathy
CN107149643A (en) * 2016-03-02 2017-09-12 王莉 A kind of Pharmaceutical composition for treating rheumatoid arthritis

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