CN103191383B - Traditional Chinese medicine composition for treating rheumatoid arthritis - Google Patents
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Abstract
The invention relates to a traditional Chinese medicine composition for treating rheumatoid arthritis. The composition comprises the following traditional Chinese medicine raw materials by weight: 20-30g of gypsum, 15-20g of common anemarrhena rhizome, 10-15g of cassia twig, 10-15g of white paeony root, 12-15g of divaricate saposhnikovia root, 25-30g of honeysuckle stem, 40-50g of radix rehmanniae, 18-25g of Chinese clematis root, 15-20g of incised notopterygium rhizome and root, 10-15g of doubleteeth pubescent angelica root, 6-9g of mint, 10-15g of cicada slough, 25-30g of orientvine vine, 30-35g of radix astragali, 25-30g of salvia miltiorrhiza, 15-20g of largehead atractylodes rhizome, 10-15g of honeysuckle, 15-20g of Chinese angelica, 10-15g of cibot rhizome, 6-9g of dried ginger, 12-15g of paniculate swallowwort root, 12-15g of monkshood, 10-15g of Indian bread and 3-6g of liquorice. The composition has the beneficial effects that through dialectical compatibility, the medicine components in the composition supplement each other in actions, have synergistic action and jointly achieve the functions of invigorating the spleen and benefiting qi, tonifying the liver and benefiting the kidney, promoting blood circulation to remove meridian obstruction, clearing away heat and toxic materials and eliminating dampness to remove wind, thus achieving the aim of treating rheumatoid arthritis; and the composition is wide in medicine sources of the components, is simple and convenient to prepare and has mild medicine properties and no toxic or side effects.
Description
Technical field:
The present invention relates to a kind of field of Chinese medicines, specifically a kind of Chinese medicine composition for the treatment of rheumatoid arthritis.
Background technology:
Rheumatoid arthritis is the chronic systemic inflammatory disease that a kind of cause of disease not yet understands, taking pathological changes outside chronic, symmetry, many synovial jointss inflammation and joint as main clinical manifestation, belongs to autoimmune inflammatory diseases.Modern medicine think rheumatoid arthritis be one with the closely-related disease of factor such as environment, cell, virus, heredity, gonadal hormone and the neural mental status.This disease is apt to occur in the little joints such as hands, wrist, foot, and outbreak, is symmetric repeatedly.Main clinical manifestation is arthropathy, and arthrosis is often symmetry, involves little joint, the most common with the multitudinous toe joint of the proximal interphalangeal joint of hands, carpal joint, foot, seriously involves the He Ji joints, large joint such as elbow, shoulder ankle, knee joint.End-stage patients are mainly joint dislocation, subluxation, deformity change, movable serious hindrance, and patient can't take care of oneself.Therefore, patient with rheumatoid arthritis should be treated in time.
At present, clinical treatment method has multiple: the one, and pain relieving western medicine.Can only pain relieving, can not control pain, long-term taking easily produces dependency and toxic and side effects.The 2nd, the naturopathy including electrotherapy, infrared ray radiation, thermotherapy.Can not effect a radical cure, can only benumb neural lenitive symptom.The 3rd, massage acupuncture and moxibustion therapy.To alleviate patient's clinical symptoms as main, but not radical cure means.The 4th, block therapy.Local anesthesia is with temporary transient pain relieving, and drug effect later symptom returns.The 5th, operative treatment.The patient who is applicable to operation is few, and expense is high, wound is large, convalescent period is long, easily recurrence.
The traditional Chinese medical science is thought the generation of rheumatoid arthritis, and it is low that it causes immunity of organisms mainly due to reasons (endogenous cause of ill, exopathogenic factor) such as fatigue, wound, infection, invade with weakened body resistance, heresy and the turbid congestion of expectorant relevant.Function virtual loss, wind, cold, wet pathogen is invaded in an opponent's defence body and is stagnated joint, meridians and cause.Because of kidney governing bones spermatogenesis, foster marrow.As deficiency of kidney-QI, can not main bone, just can there is bone diseases in foster marrow; Liver main warp network, domination whole body ligament and joint motions, as excessive rising of liver-YANG, just deficiency of liver-blood can occur twitching pain of muscle, numbness, bend and stretch difficulty, even arthroncus, the symptom such as scorching hot, lopsided; The spleen has the function to transport and transform nutrients, and main muscle, if spleen loses transporting, can not nourish skin and can occur the atrophy of aching of muscle joint tissue.
According to theory of Chinese medical science, for the pathogeny of rheumatoid arthritis, to regulate vital organs of the human body function as the total method for the treatment of, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention:
The present invention is in order to overcome the deficiencies in the prior art, provides that a kind of preparation is easy, medicine source is wide, cost is low, good effect, the Chinese medicine composition of the treatment rheumatoid arthritis that toxic and side effects is little.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, it is characterized in that being formed by the raw material of Chinese medicine of following weight proportion: Gypsum Fibrosum 20-30g, Rhizoma Anemarrhenae 15-20g, Ramulus Cinnamomi 10-15g, Radix Paeoniae Alba 10-15g, Radix Saposhnikoviae 12-15g, Caulis Lonicerae 25-30g, Radix Rehmanniae 40-50g, Radix Clematidis 18-25g, Rhizoma Et Radix Notopterygii 15-20g, Radix Angelicae Pubescentis 10-15g, Herba Menthae 6-9g, Periostracum Cicadae 10-15g, Caulis Sinomenii 25-30g, Radix Astragali 30-35g, Radix Salviae Miltiorrhizae 25-30g, Rhizoma Atractylodis Macrocephalae 15-20g, Flos Lonicerae 10-15g, Radix Angelicae Sinensis 15-20g, Rhizoma Cibotii 10-15g, Rhizoma Zingiberis 6-9g, Radix Cynanchi Paniculati 12-15g, Radix Aconiti Lateralis Preparata 12-15g, Poria 10-15g, Radix Glycyrrhizae 3-6g.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, it is characterized in that being made up of the raw material of Chinese medicine of following weight proportion: Gypsum Fibrosum 30g, Rhizoma Anemarrhenae 15g, Ramulus Cinnamomi 15g, Radix Paeoniae Alba 15g, Radix Saposhnikoviae 12g, Caulis Lonicerae 30g, Radix Rehmanniae 50g, Radix Clematidis 18g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, Herba Menthae 9g, Periostracum Cicadae 10g, Caulis Sinomenii 30g, Radix Astragali 30g, Radix Salviae Miltiorrhizae 30g, Rhizoma Atractylodis Macrocephalae 15g, Flos Lonicerae 15g, Radix Angelicae Sinensis 15g, Rhizoma Cibotii 15g, Rhizoma Zingiberis 9g, Radix Cynanchi Paniculati 15g, Radix Aconiti Lateralis Preparata 12g, Poria 15g, Radix Glycyrrhizae 6g.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In the present invention in drug composition: Gypsum Fibrosum has effect that clearing away heat-fire, relieving restlessness quench the thirst; The Rhizoma Anemarrhenae Rhizoma Anemarrhenae has clearing away heat-fire, the effect of promoting the production of body fluid and moisturizing; Ramulus Cinnamomi has effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; The Radix Paeoniae Alba has effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Radix Saposhnikoviae has effect that expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion are jerked surely; Caulis Lonicerae has heat-clearing and toxic substances removing, dispelling wind dredging collateral effect; The Radix Rehmanniae has effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, pain relieving regulating menstruation; Radix Clematidis has effect of expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the loose hypochondriac lump; Rhizoma Et Radix Notopterygii has effect of loose exterior cold, wind-damp dispelling, sharp joint, pain relieving; Radix Angelicae Pubescentis has effect of expelling wind and dampness, dispersing cold for relieving pain; Herba Menthae has effect of dispelling wind and heat pathogens, clear profit removing toxic substances, dispersing the stagnated live-QI to relieve the stagnation of QI; Effect that Periostracum Cicadae has dispelling wind-heat, rash sore-throat relieving, removing nebula to improve visual acuity, expellings wind and relieving convulsion.Caulis Sinomenii has wind-damp dispelling, the meridian dredging, effect of diuresis; The Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling is transported malicious effect; Radix Salviae Miltiorrhizae has effect of promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, the antiabortive effect of hidroschesis; Flos Lonicerae has effect of heat-clearing and toxic substances removing; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation; Rhizoma Cibotii has the effect in invigorating the liver and kidney, strong spinal column, wind-damp dispelling, sharp joint; Rhizoma Zingiberis has that warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, dampness expectorant, effect of warming the lung to resolve fluid-retention; Radix Cynanchi Paniculati has effect of analgesia, cough-relieving, inducing diuresis to remove edema, promoting blood circulation and detoxication; Radix Aconiti Lateralis Preparata has recuperating depleted YANG and rescuing the patient from collapse, mends effect fiery supporing yang, dispersing cold for relieving pain; Poria has effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, plays altogether invigorating the spleen and benefiting QI, the liver and the kidney tonifying, promoting blood circulation to remove obstruction in the collateral, heat-clearing and toxic substances removing, dampness and goes effect of wind, thereby reach the object for the treatment of rheumatoid arthritis.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, has no side effect, and total effective rate reaches 94.8%, and cure rate reaches 36.5%.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, its raw material of Chinese medicine by following weight proportion forms: Gypsum Fibrosum 20-30g, Rhizoma Anemarrhenae 15-20g, Ramulus Cinnamomi 10-15g, Radix Paeoniae Alba 10-15g, Radix Saposhnikoviae 12-15g, Caulis Lonicerae 25-30g, Radix Rehmanniae 40-50g, Radix Clematidis 18-25g, Rhizoma Et Radix Notopterygii 15-20g, Radix Angelicae Pubescentis 10-15g, Herba Menthae 6-9g, Periostracum Cicadae 10-15g, Caulis Sinomenii 25-30g, Radix Astragali 30-35g, Radix Salviae Miltiorrhizae 25-30g, Rhizoma Atractylodis Macrocephalae 15-20g, Flos Lonicerae 10-15g, Radix Angelicae Sinensis 15-20g, Rhizoma Cibotii 10-15g, Rhizoma Zingiberis 6-9g, Radix Cynanchi Paniculati 12-15g, Radix Aconiti Lateralis Preparata 12-15g, Poria 10-15g, Radix Glycyrrhizae 3-6g.
Chinese medicine composition of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soak 20～30 minutes, then add water and do not have approximately 8 centimetres of powder, decoct.First adopt intense fire to decoct, after boiling, with slow fire boiling 20～30 minutes, take concoction; Add water and decoct for the second time again, after water boils, decoct and take concoction for 15～20 minutes.Twice decoction removed slag after extracting juice and merged.
Embodiment 2: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, its raw material of Chinese medicine by following weight forms: Gypsum Fibrosum 30g, Rhizoma Anemarrhenae 15g, Ramulus Cinnamomi 15g, Radix Paeoniae Alba 15g, Radix Saposhnikoviae 12g, Caulis Lonicerae 30g, Radix Rehmanniae 50g, Radix Clematidis 18g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, Herba Menthae 9g, Periostracum Cicadae 10g, Caulis Sinomenii 30g, Radix Astragali 30g, Radix Salviae Miltiorrhizae 30g, Rhizoma Atractylodis Macrocephalae 15g, Flos Lonicerae 15g, Radix Angelicae Sinensis 15g, Rhizoma Cibotii 15g, Rhizoma Zingiberis 9g, Radix Cynanchi Paniculati 15g, Radix Aconiti Lateralis Preparata 12g, Poria 15g, Radix Glycyrrhizae 6g.
Embodiment 3: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, its raw material of Chinese medicine by following weight forms: Gypsum Fibrosum 20g, Rhizoma Anemarrhenae 20g, Ramulus Cinnamomi 10g, Radix Paeoniae Alba 10g, Radix Saposhnikoviae 15g, Caulis Lonicerae 25g, Radix Rehmanniae 40g, Radix Clematidis 25g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 10g, Herba Menthae 6g, Periostracum Cicadae 15g, Caulis Sinomenii 25g, Radix Astragali 35g, Radix Salviae Miltiorrhizae 25g, Rhizoma Atractylodis Macrocephalae 20g, Flos Lonicerae 10g, Radix Angelicae Sinensis 20g, Rhizoma Cibotii 10g, Rhizoma Zingiberis 6g, Radix Cynanchi Paniculati 12g, Radix Aconiti Lateralis Preparata 15g, Poria 10g, Radix Glycyrrhizae 3g.
Embodiment 3: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, its raw material of Chinese medicine by following weight forms: Gypsum Fibrosum 25g, Rhizoma Anemarrhenae 18g, Ramulus Cinnamomi 13g, Radix Paeoniae Alba 12g, Radix Saposhnikoviae 14g, Caulis Lonicerae 28g, Radix Rehmanniae 45g, Radix Clematidis 20g, Rhizoma Et Radix Notopterygii 16g, Radix Angelicae Pubescentis 12g, Herba Menthae 8g, Periostracum Cicadae 13g, Caulis Sinomenii 26g, Radix Astragali 32g, Radix Salviae Miltiorrhizae 29g, Rhizoma Atractylodis Macrocephalae 19g, Flos Lonicerae 13g, Radix Angelicae Sinensis 18g, Rhizoma Cibotii 12g, Rhizoma Zingiberis 8g, Radix Cynanchi Paniculati 14g, Radix Aconiti Lateralis Preparata 13g, Poria 12g, Radix Glycyrrhizae 5g.
Treat a Chinese medicine composition for rheumatoid arthritis, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied for many years clinically, clinical observation case 96 examples, male 33 examples, female's 63 examples, at 30～75 years old age, the course of disease all reaches more than 6 weeks.
Two, usage and dosage: when clinical practice, component, consumption in compositions are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.Potion on the one, the about 450ml of twice extracting juice of decocting, divides and takes for early, middle and late three times.It within 15th, is a course for the treatment of.
Three, criterion of therapeutical effect:
(1) clinical cure: symptom, sign disappear, it is normal that functional activity recovers, and laboratory leading indicator is recovered or is approached normal;
(2) effective: symptom, sign disappear substantially, and function of joint is recovered substantially, can participate in normal work, laboratory leading indicator is obviously improved, decline degree >=50%;
(3) effective: symptom, sign alleviate, and life can take care of oneself.Laboratory leading indicator is also improved;
(4) invalid: symptom, sign and laboratory leading indicator are without improvement.
Four, therapeutic effect: in clinical observation case, take medicine 2-10 the course for the treatment of, recovery from illness 35 examples, effective 45 examples, effective 11 examples, invalid 5 examples.During treatment, there is not toxic and side effects.
Five, model case:
1, Hu, man, 42 years old, first have several thoughtful some months lassitude and weak, lose weight, the symptom such as anorexia, with the rear left gonalgia.Be rheumatoid arthritis through hospital diagnosis.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, pain symptom alleviates, and other symptoms are clearly better; Continue and take 4 courses for the treatment of, pain symptom disappears, movable recovery normally.
2, Qi, female, 46 years old, occur that without obvious inducement the both hands palm refers to, interphalangeal joint swells and ache, joint stuffiness, the state of an illness increases the weight of gradually, and occurs extremity many places arthralgia, and limitation of movement, is rheumatic arthritis through hospital diagnosis.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, the each arthralgia of extremity obviously alleviates, and can descend and walk; Continue and take 2 courses for the treatment of, pain symptom disappears substantially, and function of joint is recovered substantially.
3, permitted certain, man, 55 years old, whole body arthralgia engender the right hand four fingers and left index finger swollen joint before this, can not stretch, the equal swelling of wrist and ankle joint, on right shoulder, lift limited, lumbago, difficulty in walking, simultaneously with symptoms such as dizziness and blurred vision, very pain of joint in the time that cloudy day and moral replace.Be rheumatic arthritis through hospital diagnosis.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, all symptoms make moderate progress; Continue and take 2 courses for the treatment of, articulations digitorum manus, ankle joint swell and ache and disappear completely, can walk as normal person.
Claims (2)
1. treat the Chinese medicine composition of rheumatoid arthritis for one kind, it is characterized in that being formed by the raw material of Chinese medicine of following weight proportion: Gypsum Fibrosum 20-30g, Rhizoma Anemarrhenae 15-20g, Ramulus Cinnamomi 10-15g, Radix Paeoniae Alba 10-15g, Radix Saposhnikoviae 12-15g, Caulis Lonicerae 25-30g, Radix Rehmanniae 40-50g, Radix Clematidis 18-25g, Rhizoma Et Radix Notopterygii 15-20g, Radix Angelicae Pubescentis 10-15g, Herba Menthae 6-9g, Periostracum Cicadae 10-15g, Caulis Sinomenii 25-30g, Radix Astragali 30-35g, Radix Salviae Miltiorrhizae 25-30g, Rhizoma Atractylodis Macrocephalae 15-20g, Flos Lonicerae 10-15g, Radix Angelicae Sinensis 15-20g, Rhizoma Cibotii 10-15g, Rhizoma Zingiberis 6-9g, Radix Cynanchi Paniculati 12-15g, Radix Aconiti Lateralis Preparata 12-15g, Poria 10-15g, Radix Glycyrrhizae 3-6g.
2. a kind of Chinese medicine composition for the treatment of rheumatoid arthritis according to claim 1, it is characterized in that being made up of the raw material of Chinese medicine of following weight proportion: Gypsum Fibrosum 30g, Rhizoma Anemarrhenae 15g, Ramulus Cinnamomi 15g, Radix Paeoniae Alba 15g, Radix Saposhnikoviae 12g, Caulis Lonicerae 30g, Radix Rehmanniae 50g, Radix Clematidis 18g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, Herba Menthae 9g, Periostracum Cicadae 10g, Caulis Sinomenii 30g, Radix Astragali 30g, Radix Salviae Miltiorrhizae 30g, Rhizoma Atractylodis Macrocephalae 15g, Flos Lonicerae 15g, Radix Angelicae Sinensis 15g, Rhizoma Cibotii 15g, Rhizoma Zingiberis 9g, Radix Cynanchi Paniculati 15g, Radix Aconiti Lateralis Preparata 12g, Poria 15g, Radix Glycyrrhizae 6g.
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| CN103656216A (en) * | 2013-12-12 | 2014-03-26 | 黄根强 | Traditional Chinese medicine for treating rheumatoid arthritis |
| CN104147163B (en) * | 2014-08-04 | 2016-08-24 | 郭志文 | A kind of external application Chinese medicine agent treating rheumatic arthritis and preparation method thereof |
| CN104382992A (en) * | 2014-11-13 | 2015-03-04 | 邹士东 | Pharmaceutical composition for treating rheumatoid arthritis |
| CN104547670A (en) * | 2014-12-22 | 2015-04-29 | 郑贺 | Traditional Chinese medicine for treating arthritis |
| CN104825751A (en) * | 2015-02-26 | 2015-08-12 | 龚正丰 | Medicine composition for treating ankylosing spondylitis |
| CN105327156A (en) * | 2015-12-01 | 2016-02-17 | 徐腾 | Fuming traditional Chinese medicine composition for treating osteoarthropathy and preparation method thereof |
| CN107149643A (en) * | 2016-03-02 | 2017-09-12 | 王莉 | A kind of Pharmaceutical composition for treating rheumatoid arthritis |
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