CN103316295B - Traditional Chinese composition for treating rheumatic arthritis - Google Patents

Traditional Chinese composition for treating rheumatic arthritis Download PDF

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CN103316295B
CN103316295B CN201310252231.7A CN201310252231A CN103316295B CN 103316295 B CN103316295 B CN 103316295B CN 201310252231 A CN201310252231 A CN 201310252231A CN 103316295 B CN103316295 B CN 103316295B
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radix
rheumatic arthritis
chinese medicine
traditional chinese
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CN103316295A (en
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孙黎明
柳晖
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Sun Liming
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Abstract

The invention relates to a traditional Chinese composition for treating rheumatic arthritis, which is prepared from the following bulk pharmaceutical chemicals in parts by weight: 10-30 parts of astragatus membranaceus, 10-30 parts of angelica sinensis, 5-20 parts of radix angelicae pubescentis, 20-10 parts of asarum, 5-20 parts of turmeric, 5-20 parts of garter snake, 5-20 parts of hurricane lamp, 10-40 parts of radix paeoniae alba, 5-20 parts of radix aconiti, 5-20 parts of monkshood, 10-30 parts of pawpaw, 10-30 parts of kadsura pepper stem, 5-20 parts of medicinal cyathula root, 5-25 parts of cassis twig, 5-20 parts of lycopodium clavatum, 10-40 parts of caulis spatholobi, 5-20 parts of gentiana macrophylla, 5-20 parts of red flower, 10-30 parts of ligusticum wallichii, 5-20 parts of peach kernel, 10-40 parts of salvia miltiorrhiza, 5-20 parts of earthworm and 10-30 parts of liquorice. The traditional Chinese composition has the efficacies of tonifying liver and nourishing spleen, warming channel and expelling cold, clearing damp and dispersing blood stasis, enriching and activating blood, stretching the muscles and smoothing the vein, and has an obvious curative effect for treating rheumatic arthritis and a reliable action.

Description

A kind of Chinese medicine composition for the treatment of rheumatic arthritis
Technical field
The present invention relates to a kind of pharmaceutical product not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of rheumatic arthritis.
Background technology
Rheumatic arthritis is a kind of common acute or chronic ICT, can recurrent exerbation involve heart.Clinical with joint and muscle migrans miserable, heavily work, pain is for feature, typical performance is slight or moderate heating, migratory polyarthritis, affected joints mostly is the large joint such as knee joint ankle, shoulder, elbow wrist, commonly be transferred to another joint by a joint, pathological changes local presents redness, scorching hot, severe pain some patients also has several joint to fall ill simultaneously, atypical patient only has arthralgia and shows without other inflammation, acute inflammation generally disappears in 2-4 week and does not stay sequela, but normal recurrent exerbation.If active rheumatism affects heart, myocarditis can be there is and even leave over valve disorder.The Western medicine of current treatment rheumatoid diseases is a lot, and the curative effect that these medicines have is low, side effect large, as dirty in infringement liver, stomach etc., hormone medicine causes human body to get fat, edema, what have is expensive, and is difficult to effect a permanent cure, and can only play lenitive effect.
The traditional Chinese medical science is thought, rheumatic arthritis belongs to " arthromyodynia " category.Residence place is moist, touches and emits wind and rain etc. to be the external condition producing arthromyodynia; Ferritic is weak, insufficiency of vital energy and blood, and interspaces of skin and muscles being loose is the intrinsic factor producing arthromyodynia.Wet heresy of wind and cold heat is taken advantage of a weak point in opponent's defence invasion, meridians muscle arthrosis of being detained, and QI and blood impatency is obstructed, thus the tingle pain of generation podomere, all diseases of joint stuffiness, if based on intenseness of heat or damp and hotly accumulate steaming, then see that joint is red, swollen, hot, bitterly; If cold-damp is contained partially, joint cold type of pain, pain increase in intensity under coldness; If obstinate disease, also can occur insufficiency of vital energy and blood, deficiency of both the liver and kidney or pathogenic factor go deep into the changes such as internal organs.
According to theory of Chinese medical science, for the pathogeny of rheumatic arthritis, with invigorating the liver and kidney, dispersing cold for relieving pain, expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral for the rule for the treatment of, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome prior art western medicines in treatment rheumatic arthritis, to there is not obvious, the easy recurrence of curative effect, treatment cycle long and there is the deficiency of side effect, the invention provides a kind of prepare easy, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of rheumatic arthritis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of rheumatic arthritis, it is characterized in that: its raw material of Chinese medicine and weight are: Radix Astragali 10-30 part, Radix Angelicae Sinensis 10-30 part, Radix Angelicae Pubescentis 5-20 part, Herba Asari 2-10 part, Rhizoma Curcumae Longae 5-20 part, Zaocys 5-20 part, Radix Saposhnikoviae 5-20 part, Radix Paeoniae Alba 10-40 part, Radix Aconiti 5-20 part, Radix Aconiti Lateralis Preparata 5-20 part, Fructus Chaenomelis 10-30 part, Caulis Piperis Kadsurae 10-30 part, Radix Cyathulae 5-20 part, Ramulus Cinnamomi 5-25 part, Herba Lycopodii 5-20 part, Caulis Spatholobi 10-40 part, Radix Gentianae Macrophyllae 5-20 part, Flos Carthami 5-20 part, Rhizoma Chuanxiong 10-30 part, Semen Persicae 5-20 part, Radix Salviae Miltiorrhizae 10-40 part, Pheretima 5-20 part, Radix Glycyrrhizae 10-30 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of rheumatic arthritis, is characterized in that: its raw material of Chinese medicine and weight are: the Radix Astragali 20 parts, Radix Angelicae Sinensis 20 parts, Radix Angelicae Pubescentis 10 parts, Herba Asari 6 parts, 10 parts, Rhizoma Curcumae Longae, Zaocys 10 parts, Radix Saposhnikoviae 10 parts, the Radix Paeoniae Alba 30 parts, Radix Aconiti 10 parts, Radix Aconiti Lateralis Preparata 10 parts, Fructus Chaenomelis 20 parts, Caulis Piperis Kadsurae 20 parts, Radix Cyathulae 10 parts, Ramulus Cinnamomi 15 parts, Herba Lycopodii 10 parts, Caulis Spatholobi 30 parts, Radix Gentianae Macrophyllae 10 parts, 10 parts, Flos Carthami, Rhizoma Chuanxiong 20 parts, 10 parts, Semen Persicae, Radix Salviae Miltiorrhizae 30 parts, Pheretima 10 parts, 20 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: the Radix Astragali has effect that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling fortune is malicious; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation; Radix Angelicae Pubescentis has effect of expelling wind and dampness, dispersing cold for relieving pain; Herba Asari has the cold expelling that induces sweat, wind-expelling pain-stopping, warming the lung to resolve fluid-retention, sensible effect; Rhizoma Curcumae Longae has effect of removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia; Zaocys has effect of wind-damp dispelling, the meridian dredging; Effect that Radix Saposhnikoviae has expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion are jerked surely; The Radix Paeoniae Alba has effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Radix Aconiti has effect of expelling wind and removing dampness, antalgic; Radix Aconiti Lateralis Preparata has recuperating depleted YANG and rescuing the patient from collapse, mends effect that is fiery supporing yang, dispersing cold for relieving pain; Fructus Chaenomelis has effect of suppressing the hyperactive liver relaxing muscles and tendons, stomach function regulating removing dampness; Caulis Piperis Kadsurae has effect of wind-damp dispelling, the meridian dredging, stopping numbness pain; Radix Cyathulae has effect of promoting blood circulation to restore menstrual flow, expelling wind and removing dampness, easing joint movement, inducing diuresis for treating stranguria syndrome; Ramulus Cinnamomi has effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; Herba Lycopodii has effect of expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons to promote blood circulation; Caulis Spatholobi has to enrich blood invigorates blood circulation, relaxes through effect of dredging collateral; Radix Gentianae Macrophyllae has effect of Eradicates rheumatism, relaxing muscles and tendons network, clearind deficient heat; Flos Carthami has effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Rhizoma Chuanxiong has effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; Semen Persicae has effect of blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation; Radix Salviae Miltiorrhizae has effect of promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Pheretima has effect of clearing heat for calming endogenous wind, lung-clearing asthma-relieving, inducing diuresis for treating stranguria syndrome, current meridians; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component, through dialectical compatibility, helps using mutually assistant, play tonifying liver spleen invigorating, dispelling cold by warming the meridian, damp eliminating blood stasis dispelling altogether, enrich blood invigorate blood circulation, effect of channels sootheing and network vessel quickening, treating both the principal and secondary aspects of a disease is reached to the treatment of rheumatic arthritis.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is reliably evident in efficacy, mild in medicine property and, do not occur toxic and side effects, effective percentage reaches 94%, cure rate 65%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for rheumatic arthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 20g, Radix Angelicae Sinensis 20g, Radix Angelicae Pubescentis 10g, Herba Asari 6g, Rhizoma Curcumae Longae 10g, Zaocys 10g, Radix Saposhnikoviae 10g, the Radix Paeoniae Alba 30 g, Radix Aconiti 10g, Radix Aconiti Lateralis Preparata 10g, Fructus Chaenomelis 20g, Caulis Piperis Kadsurae 20g, Radix Cyathulae 10g, Ramulus Cinnamomi 15g, Herba Lycopodii 10g, Caulis Spatholobi 30g, Radix Gentianae Macrophyllae 10g, Flos Carthami 10g, Rhizoma Chuanxiong 20g, Semen Persicae 10g, Radix Salviae Miltiorrhizae 30g, Pheretima 10g, Radix Glycyrrhizae 20g.
Embodiment 2
Treat a Chinese medicine composition for rheumatic arthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 10g, Radix Angelicae Sinensis 30g, Radix Angelicae Pubescentis 15g, Herba Asari 5g, Rhizoma Curcumae Longae 20g, Zaocys 15g, Radix Saposhnikoviae 5g, the Radix Paeoniae Alba 20 g, Radix Aconiti 20g, Radix Aconiti Lateralis Preparata 15g, Fructus Chaenomelis 30g, Caulis Piperis Kadsurae 10g, Radix Cyathulae 20g, Ramulus Cinnamomi 12g, Herba Lycopodii 5g, Caulis Spatholobi 20g, Radix Gentianae Macrophyllae 12g, Flos Carthami 20g, Rhizoma Chuanxiong 15g, Semen Persicae 5g, Radix Salviae Miltiorrhizae 40g, Pheretima 12g, Radix Glycyrrhizae 30g.
Embodiment 3
Treat a Chinese medicine composition for rheumatic arthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 30g, Radix Angelicae Sinensis 10g, Radix Angelicae Pubescentis 12g, Herba Asari 2g, Rhizoma Curcumae Longae 15g, Zaocys 20g, Radix Saposhnikoviae 20g, Radix Paeoniae Alba 15g, Radix Aconiti 5g, Radix Aconiti Lateralis Preparata 12g, Fructus Chaenomelis 15g, Caulis Piperis Kadsurae 30g, Radix Cyathulae 5g, Ramulus Cinnamomi 20g, Herba Lycopodii 15g, Caulis Spatholobi 40g, Radix Gentianae Macrophyllae 5g, Flos Carthami 12g, Rhizoma Chuanxiong 30g, Semen Persicae 12g, Radix Salviae Miltiorrhizae 20g, Pheretima 5g, Radix Glycyrrhizae 25g.
Embodiment 4
Treat a Chinese medicine composition for rheumatic arthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 25g, Radix Angelicae Sinensis 15g, Radix Angelicae Pubescentis 20g, Herba Asari 10g, Rhizoma Curcumae Longae 5g, Zaocys 12g, Radix Saposhnikoviae 15g, the Radix Paeoniae Alba 40 g, Radix Aconiti 12g, Radix Aconiti Lateralis Preparata 20g, Fructus Chaenomelis 10g, Caulis Piperis Kadsurae 25g, Radix Cyathulae 15g, Ramulus Cinnamomi 5g, Herba Lycopodii 20g, Caulis Spatholobi 25g, Radix Gentianae Macrophyllae 20g, Flos Carthami 15g, Rhizoma Chuanxiong 10g, Semen Persicae 15g, Radix Salviae Miltiorrhizae 25g, Pheretima 15g, Radix Glycyrrhizae 10g.
Embodiment 5
Treat a Chinese medicine composition for rheumatic arthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 15g, Radix Angelicae Sinensis 25g, Radix Angelicae Pubescentis 5g, Herba Asari 8g, Rhizoma Curcumae Longae 12g, Zaocys 5g, Radix Saposhnikoviae 12g, the Radix Paeoniae Alba 10 g, Radix Aconiti 15g, Radix Aconiti Lateralis Preparata 5g, Fructus Chaenomelis 25g, Caulis Piperis Kadsurae 15g, Radix Cyathulae 12g, Ramulus Cinnamomi 25g, Herba Lycopodii 12g, Caulis Spatholobi 10g, Radix Gentianae Macrophyllae 15g, Flos Carthami 5g, Rhizoma Chuanxiong 25g, Semen Persicae 20g, Radix Salviae Miltiorrhizae 10g, Pheretima 20g, Radix Glycyrrhizae 15g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 7 centimetres, decocts.Intense fire is adopted to decoct at a simmer, with slow fire boiling 20 ~ 30 minutes after boiling; Second decocts, and adds water and does not have powder about 5 centimetres, decoct, and decocts 15 ~ 20 minutes after water boils.Decoct extracting juice twice, merge.
With a kind of Chinese medicine composition for the treatment of rheumatic arthritis given by embodiment 1, do clinical efficacy and be summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 100 example, man 55 example, female 45 example, 40 ~ 65 years old age.
Two, diagnosis basis:
1, the large joint of extremity, the migration such as wrist, elbow, shoulder, ankle, knee joint, hip are altered pain or are swollen and ache;
2, there is hemolytic streptococcal infection history before disease more;
3, affected joints red, swollen, hot, pain or swell and ache, movable function is limited, and some cases can have low grade fever, erythema nodosum or erythema iris or heart change etc. concurrently;
4, active stage, erythrocyte sedimentation rate generally speeded more, and nonmobile phase is normal, and the many positives of active stage anti-O must be shown in have erythema iris or nodiform erythema as anti-O negative patient, otherwise can not examine as FENGGUAN is scorching;
5, the rarely seen soft tissue swelling of affected joints, without sclerotin change.
Three, usage and dosage: during clinical practice, the amounts of components in compositions takes the circumstances into consideration increase and decrease according to the body weight of patient and age.Potion on the one, decocting twice extracting juice is about 300ml, and point morning, evening take for twice.It within six days, is a course for the treatment of.
Four, criterion of therapeutical effect:
1, cure: symptom all disappears, functional activity is all normal, and main physical and chemical index etc. are all normal;
2, effective: symptomatology or cardinal symptom disappear, and function of joint is recovered substantially, can participate in normal work and work, main physical and chemical index is normal;
3, effective: cardinal symptom all disappears, and function of joint is substantially recovered or is clearly better, and can't take care of oneself and transfers self-care to, work work capacity is recovered to some extent;
4, invalid: to compare each side with before treatment all without progressive.
Five, therapeutic effect: in this clinical observation case, takes medicine 3-10 the course for the treatment of, and recovery from illness 65 example, follows up a case by regular visits to and have no recurrence; Effective 15 examples, effective 14 examples, invalid 6 examples.There is not toxic and side effects in treatments period.
Six, model case:
Case 1:
Cui, man, 46 years old.Suffer from rheumatic arthritis, affected joints be red, swollen, hot, pain or swell and ache, movable function is limited, in many ways seeks medical advice invalid.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom alleviates; Continue to take 2 courses for the treatment of, symptom disappears completely, and functional activity recovers normal, cures.
Case 2:
Zhang, man, 52 years old.Private prosecution: by rheumatism before 3 years, conscious knee joint, ankle, carpal joint and around miserable distending pain, bend and stretch hurt like hell, walk difficult, overcast and rainyly increases the weight of, and fine day obviously alleviates.Though repeatedly acupuncture therapy, always can not cure.Take 4 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom disappears substantially, and function of joint is recovered substantially; Continue to take 3 courses for the treatment of, symptom all disappears, and functional activity is all normal.
Case 3:
Hu, female, 48 years old.Had a cold before 2 years, whenever the cloudy day, rain, cold sky two points, toe, double knee joint pain, within nearly 1 year, disease increases the weight of, the existing distortion of forefinger, middle articulations digitorum manus, back and whole body arthralgia, overcast and rainy enter hurt like hell especially after the winter.Once the medicine such as long-term steroid, analgesia, and attempted various physical therapy modalities, effect is all not obvious.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom takes a turn for the better; Continue to take 3 courses for the treatment of, transference cure, activity freely.Follow up a case by regular visits to so far without recurrence.

Claims (1)

1. treat a Chinese medicine composition for rheumatic arthritis, it is characterized in that: its raw material of Chinese medicine and weight proportion are: Radix Astragali 20g, Radix Angelicae Sinensis 20g, Radix Angelicae Pubescentis 10g, Herba Asari 6g, Rhizoma Curcumae Longae 10g, Zaocys 10g, Radix Saposhnikoviae 10g, Radix Paeoniae Alba 30g, Radix Aconiti 10g, Radix Aconiti Lateralis Preparata 10g, Fructus Chaenomelis 20g, Caulis Piperis Kadsurae 20g, Radix Cyathulae 10g, Ramulus Cinnamomi 15g, Herba Lycopodii 10g, Caulis Spatholobi 30g, Radix Gentianae Macrophyllae 10g, Flos Carthami 10g, Rhizoma Chuanxiong 20g, Semen Persicae 10g, Radix Salviae Miltiorrhizae 30g, Pheretima 10g, Radix Glycyrrhizae 20g.
CN201310252231.7A 2013-06-24 2013-06-24 Traditional Chinese composition for treating rheumatic arthritis Expired - Fee Related CN103316295B (en)

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Publication number Priority date Publication date Assignee Title
CN105168445A (en) * 2015-10-12 2015-12-23 新乡医学院 Traditional Chinese medicine composition for treating rheumatic arthritis
CN105596992A (en) * 2016-01-04 2016-05-25 孙友彬 Traditional Chinese medicine composition for treating rheumatism arthritis
CN105561041A (en) * 2016-02-25 2016-05-11 缪建林 Formula for treating injuries and rheumatic arthritis of bone joints, waists, necks, shoulders and meniscus
CN105878932A (en) * 2016-05-26 2016-08-24 张晓燕 Traditional Chinese medicine composition for treating arthralgia
CN110115751A (en) * 2018-02-06 2019-08-13 北京德氧生健康文化传播有限公司 A kind of holography that treating interior traumatosis pain follows repaired pain-stopping external use liquid medicine and preparation method thereof
CN113521233A (en) * 2021-05-28 2021-10-22 北京信德康中医药研究院(普通合伙) Medicine for dredging channels and collaterals and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN1117391A (en) * 1994-08-24 1996-02-28 冯永德 Medicine for treating rheumatic disease
CN101919988B (en) * 2009-06-10 2011-10-26 胡国伟 Medicine compound for curing rheumatism rheumatoid arthritis and preparation method thereof
CN101972453B (en) * 2010-10-29 2012-01-25 韩世昌 Chinese medicinal liquor for treating rheumatic and rheumatoid arthritis and preparation method thereof

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