CN103536777B - Traditional Chinese medicinal composition for treating knee osteoarthritis - Google Patents
Traditional Chinese medicinal composition for treating knee osteoarthritis Download PDFInfo
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- CN103536777B CN103536777B CN201310510667.1A CN201310510667A CN103536777B CN 103536777 B CN103536777 B CN 103536777B CN 201310510667 A CN201310510667 A CN 201310510667A CN 103536777 B CN103536777 B CN 103536777B
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Abstract
The invention relates to a traditional Chinese medicinal composition for treating knee osteoarthritis. The traditional Chinese medicinal composition is characterized by comprising the following traditional Chinese medicinal raw materials in parts by weight: 5-25 parts of radix clematidis, 5-25 parts of herba taxilli, 5-25 parts of lycopodium clavatum, 10-30 parts of suberect spatholobus stem, 5-25 parts of medicinal cyathula root, 10-30 parts of pawpaw, 5-25 parts of rhizoma corydalis, 5-20 parts of divaricate saposhnikovia root, 5-20 parts of notopterygium root, 5-20 parts of pubescent angelica root, 5-25 parts of large-leaved gentian, 5-25 parts of bighead atractylodes rhizome, 5-25 parts of poria, 5-20 parts of golden cypress, 5-20 parts of rhizoma atractylodis, 5-25 parts of Chinese angelica, 5-15 parts of cassia twig, 5-25 parts of gastrodia elata, 5-25 parts of paniculate swallowwort root, 5-15 parts of pseudo-ginseng and 5-15 parts of liquorice. The traditional Chinese medicinal composition has the functions of nourishing yin, tonifying kidney, eliminating phlegm, removing wind, diminishing swelling, relieving pain, activating blood circulation to remove stasis, and strengthening tendons and bones, and has a remarkable curative effect and reliable action for treating knee osteoarthritis; the components are wide in sources and convenient to prepare, and do not have toxic or side effects.
Description
Technical field
The present invention relates to a kind of pharmaceutical product not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of knee osteoarthritis.
Background technology
Knee osteoarthritis take articular cartilage degeneration as multi-faceted, the chronic inflammatory disease at many levels, in various degree of involving sclerotin, synovial membrane, joint capsule and other structures of joint of core.Its clinical manifestation mostly is that the gonalgia, swelling, dysfunction, joint are thick, Varus deformity etc.Knee osteoarthritis mostly be old people, be the disease of deficiency in origin and excess in superficiality, the long-term lacking activity due to the gonalgia in addition, cause local QI-blood circulation not enough, muscle is become homeless foster, numbness of aching, and of a specified duration easily causes myoatrophy and osteoporosis.The method of current treatment knee osteoarthritis has endo-medicine, external used medicine, operation, acupuncture, massage, physiotherapy and rehabilitation etc.Endo-medicine for patients toxic and side effects is comparatively large, and usual wound of performing the operation is comparatively large, and acupuncture, massage, physical therapy therapy then exist the shorter shortcoming of curative effect lasting time.
Motherland's medical science is thought, knee osteoarthritis is by caused by liver and kidney deficiency, and cold-damp is invaded, and retardance meridians, caused by phlegm-turbidity and blood stasis blood stasis is stagnant.
According to theory of Chinese medical science, for the pathogeny of knee osteoarthritis, adopt enriching yin and nourishing kidney, eliminate the phlegm except the method for the treatment of of wind, blood-activating analgetic, carry out dialectical prescription compatibility, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome the deficiency that in prior art, the side effect of endo-medicine treatment knee osteoarthritis is comparatively large, operative treatment wound is comparatively large and physical therapy curative effect lasting time is shorter.The invention provides a kind of prepare easy, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of knee osteoarthritis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of knee osteoarthritis, it is characterized in that: its raw material of Chinese medicine and weight are: Radix Clematidis 5-25 part, Herba Taxilli 5-25 part, Herba Lycopodii 5-25 part, Caulis Spatholobi 10-30 part, Radix Cyathulae 5-25 part, Fructus Chaenomelis 10-30 part, Rhizoma Corydalis 5-25 part, Radix Saposhnikoviae 5-20 part, Rhizoma Et Radix Notopterygii 5-20 part, Radix Angelicae Pubescentis 5-20 part, Radix Gentianae Macrophyllae 5-25 part, Rhizoma Atractylodis Macrocephalae 5-25 part, Poria 5-25 part, Cortex Phellodendri 5-20 part, Rhizoma Atractylodis 5-20 part, Radix Angelicae Sinensis 5-25 part, Ramulus Cinnamomi 5-15 part, Rhizoma Gastrodiae 5-25 part, Radix Cynanchi Paniculati 5-25 part, Radix Notoginseng 5-15 part and Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of knee osteoarthritis, is characterized in that: its raw material of Chinese medicine and weight are: Radix Clematidis 15 parts, Herba Taxilli 15 parts, Herba Lycopodii 15 parts, Caulis Spatholobi 20 parts, Radix Cyathulae 15 parts, Fructus Chaenomelis 20 parts, Rhizoma Corydalis 15 parts, Radix Saposhnikoviae 12 parts, Rhizoma Et Radix Notopterygii 12 parts, Radix Angelicae Pubescentis 12 parts, Radix Gentianae Macrophyllae 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, 15 parts, Poria, Cortex Phellodendri 12 parts, Rhizoma Atractylodis 10 parts, Radix Angelicae Sinensis 15 parts, Ramulus Cinnamomi 8 parts, 15 parts, Rhizoma Gastrodiae, Radix Cynanchi Paniculati 15 parts, Radix Notoginseng 9 parts and 10 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Radix Clematidis has effect of expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, detoxicating and resolving stagnation of pathogens; Herba Taxilli has effect of invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit; Herba Lycopodii has effect of expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons to promote blood circulation; Caulis Spatholobi has to enrich blood invigorates blood circulation, relaxes through effect of dredging collateral; Radix Cyathulae has effect of promoting blood circulation to restore menstrual flow, expelling wind and removing dampness, easing joint movement, inducing diuresis for treating stranguria syndrome; Fructus Chaenomelis has effect of suppressing the hyperactive liver relaxing muscles and tendons, stomach function regulating removing dampness; Rhizoma Corydalis has effect of promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving; Effect that Radix Saposhnikoviae has expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion are jerked surely; Rhizoma Et Radix Notopterygii has effect of loose exterior cold, wind-damp dispelling, sharp joint, pain relieving; Radix Angelicae Pubescentis have expelling wind and dampness, dispersing cold for relieving pain effect; Radix Gentianae Macrophyllae has effect of Eradicates rheumatism, relaxing muscles and tendons network, clearind deficient heat; The Rhizoma Atractylodis Macrocephalae has the antiabortive effect of invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis; Poria has benefiting vital QI for tranquillizing, invigorating the spleen and regulating the stomach, dispels effect that is damp and hot, row water stopping leak; Effect that Cortex Phellodendri has heat clearing and damp drying, pathogenic fire purging removes steaming, detoxification sore treatment; Rhizoma Atractylodis have effect that is drying damp and strengthening spleen, expelling wind and cold; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation; Ramulus Cinnamomi has effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; Rhizoma Gastrodiae has effect of endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral; Radix Cynanchi Paniculati has effect of analgesia, cough-relieving, inducing diuresis to remove edema, promoting blood circulation and detoxication; Radix Notoginseng has effect of activating blood and removing stasis, hemostasis, reducing swelling and alleviating pain; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component, through dialectical compatibility, helps using mutually assistant, plays enriching yin and nourishing kidney altogether, eliminates the phlegm except effect of wind, reducing swelling and alleviating pain, blood circulation promoting and blood stasis dispelling, strong muscles and bones, reach treating both the principal and secondary aspects of a disease to the treatment of knee osteoarthritis.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is reliably evident in efficacy, mild in medicine property and, do not occur toxic and side effects, effective percentage reaches 93%, cure rate 68%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for knee osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Clematidis 15 g, Herba Taxilli 15g, Herba Lycopodii 15g, Caulis Spatholobi 20g, Radix Cyathulae 15g, Fructus Chaenomelis 20g, Rhizoma Corydalis 15 parts, Radix Saposhnikoviae 12g, Rhizoma Et Radix Notopterygii 12g, Radix Angelicae Pubescentis 12g, Radix Gentianae Macrophyllae 15g, Rhizoma Atractylodis Macrocephalae 15g, Poria 15g, Cortex Phellodendri 12g, Rhizoma Atractylodis 10g, Radix Angelicae Sinensis 15g, Ramulus Cinnamomi 8g, Rhizoma Gastrodiae 15g, Radix Cynanchi Paniculati 15g, Radix Notoginseng 9g and Radix Glycyrrhizae 10g.
Embodiment 2
Treat a Chinese medicine composition for knee osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Clematidis 10 g, Herba Taxilli 25g, Herba Lycopodii 5g, Caulis Spatholobi 30g, Radix Cyathulae 12g, Fructus Chaenomelis 25g, Rhizoma Corydalis 5g, Radix Saposhnikoviae 20g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 20g, Radix Gentianae Macrophyllae 25g, Rhizoma Atractylodis Macrocephalae 5g, Poria 20g, Cortex Phellodendri 10g, Rhizoma Atractylodis 15g, Radix Angelicae Sinensis 5g, Ramulus Cinnamomi 15g, Rhizoma Gastrodiae 10g, Radix Cynanchi Paniculati 25g, Radix Notoginseng 5g and Radix Glycyrrhizae 15g.
Embodiment 3
Treat a Chinese medicine composition for knee osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Clematidis 20g, Herba Taxilli 10g, Herba Lycopodii 25g, Caulis Spatholobi 15g, Radix Cyathulae 25g, Fructus Chaenomelis 15g, Rhizoma Corydalis 20g, Radix Saposhnikoviae 10g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 10g, Radix Gentianae Macrophyllae 20g, Rhizoma Atractylodis Macrocephalae 10g, Poria 25g, Cortex Phellodendri 5g, Rhizoma Atractylodis 12g, Radix Angelicae Sinensis 20g, Ramulus Cinnamomi 10g, Rhizoma Gastrodiae 25g, Radix Cynanchi Paniculati 5g, Radix Notoginseng 10g and Radix Glycyrrhizae 5g.
Embodiment 4
Treat a Chinese medicine composition for knee osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Clematidis 12g, Herba Taxilli 20g, Herba Lycopodii 10g, Caulis Spatholobi 25g, Radix Cyathulae 5g, Fructus Chaenomelis 30g, Rhizoma Corydalis 10 g, Radix Saposhnikoviae 15g, Rhizoma Et Radix Notopterygii 5g, Radix Angelicae Pubescentis 15g, Radix Gentianae Macrophyllae 10g, Rhizoma Atractylodis Macrocephalae 20g, Poria 5g, Cortex Phellodendri 15g, Rhizoma Atractylodis 20g, Radix Angelicae Sinensis 10g, Ramulus Cinnamomi 12g, Rhizoma Gastrodiae 5g, Radix Cynanchi Paniculati 20g, Radix Notoginseng 12g and Radix Glycyrrhizae 6g.
Embodiment 5
Treat a Chinese medicine composition for knee osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Clematidis 25 g, Herba Taxilli 5g, Herba Lycopodii 20g, Caulis Spatholobi 10g, Radix Cyathulae 20g, Fructus Chaenomelis 10g, Rhizoma Corydalis 25g, Radix Saposhnikoviae 5g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 5g, Radix Gentianae Macrophyllae 5g, Rhizoma Atractylodis Macrocephalae 25g, Poria 10g, Cortex Phellodendri 20g, Rhizoma Atractylodis 5g, Radix Angelicae Sinensis 25g, Ramulus Cinnamomi 5g, Rhizoma Gastrodiae 20g, Radix Cynanchi Paniculati 10g, Radix Notoginseng 15g and Radix Glycyrrhizae 12g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 8 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 6 centimetres, decocts 15 ~ 20 minutes after water boils.Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition for the treatment of knee osteoarthritis given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 100 example, man 54 example, female 46 example, 40 ~ 75 years old age.
Two, diagnosis basis: the diagnostic criteria with reference to knee osteoarthritis in " arthritis diagnosis and treatment draft guidelines gonarthritis in 2002 diagnostic criteria of rheumatism branch of Chinese Medical Association ":
1, the gonalgia, walking function obstacle, exacerbation of symptoms when fatigue and stair activity, involves periarticular muscles pain;
2, health check-up knee joint is unrestrained swollen, patella and inside and outside Xiyan place tenderness+, patella grinding pain, floating patella test+, it is limited that knee joint stretches flex, atrophy of quadriceps femoris.
Three, usage and dosage: during clinical practice, potion on the one, decocting twice extracting juice is about 400ml, point morning, late twice empty stomach decoction being taken warmly.It within five days, is a course for the treatment of.Treatments period is avoided cold and uncooked food the thing of pungent stimulation.
Four, criterion of therapeutical effect: the criterion of therapeutical effect with reference to knee osteoarthritis in " Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine issues:
(1) fully recover: knee joint swelling, pain disappear, flexion-extension motion scope recovers normal, and walking freely;
(2) effective: knee joint swelling substantially disappears or obviously goes down, and pain obviously alleviates, flexion-extension motion scope is normal;
(3) effective: knee joint swelling and pain all have and alleviates in various degree and alleviate, and flexion-extension motion scope is also improved;
(4) invalid: knee joint swelling and pain are all without alleviation.
Five, therapeutic effect: in this clinical observation case, takes medicine 2-10 the course for the treatment of, and recovery from illness 68 example, follows up a case by regular visits to and have no recurrence; Effective 16 examples, effective 9 examples, invalid 7 examples.There is not toxic and side effects in treatments period.
Six, model case:
Case 1:
Week certain, man, 65 years old.Nearly 1 year of two gonalgia, over nearly 1 month, right swelling and pain in knee obviously increases the weight of, and upper all needs staircase downstairs, seat dysstasia, and it is obvious to meet overcast and rainy symptom.Check: inner side tenderness under kneecap, right knee joint is micro-swollen.Examine and see: tongue is greasy in vain, stringy and rolling pulse.Diagnosis: knee osteoarthritis.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, two swelling and pain in knee obviously alleviate, and all the other symptoms are also eased; Continue to take 2 courses for the treatment of, recovery from illness.Follow up a case by regular visits to after half a year without recurrence.
Case 2:
Poplar, female, 68 years old.Existing 5 years of two knee joint sorenesses, have Knee Trauma history.Recently, knee joint soreness increases the weight of, and stair activity all needs handrail, and seat erects difficulty.X takes the photograph sheet prompting: knee joint is that bone is loose, and joint space narrows.Check: tenderness (+), mild swelling and limping around two knee joints.Diagnosis: knee osteoarthritis.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, two knee joints are ached and are alleviated, and swelling disappears, and all the other symptoms alleviate.Continue to take 2 courses for the treatment of, recovery from illness.Follow up a case by regular visits to after 1 year without recurrence.
Claims (2)
1. treat a Chinese medicine composition for knee osteoarthritis, it is characterized in that: its raw material of Chinese medicine and weight are: Radix Clematidis 5-25 part, Herba Taxilli 5-25 part, Herba Lycopodii 5-25 part, Caulis Spatholobi 10-30 part, Radix Cyathulae 5-25 part, Fructus Chaenomelis 10-30 part, Rhizoma Corydalis 5-25 part, Radix Saposhnikoviae 5-20 part, Rhizoma Et Radix Notopterygii 5-20 part, Radix Angelicae Pubescentis 5-20 part, Radix Gentianae Macrophyllae 5-25 part, Rhizoma Atractylodis Macrocephalae 5-25 part, Poria 5-25 part, Cortex Phellodendri 5-20 part, Rhizoma Atractylodis 5-20 part, Radix Angelicae Sinensis 5-25 part, Ramulus Cinnamomi 5-15 part, Rhizoma Gastrodiae 5-25 part, Radix Cynanchi Paniculati 5-25 part, Radix Notoginseng 5-15 part and Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine composition for the treatment of knee osteoarthritis according to claim 1, is characterized in that: its raw material of Chinese medicine and weight are: Radix Clematidis 15 parts, Herba Taxilli 15 parts, Herba Lycopodii 15 parts, Caulis Spatholobi 20 parts, Radix Cyathulae 15 parts, Fructus Chaenomelis 20 parts, Rhizoma Corydalis 15 parts, Radix Saposhnikoviae 12 parts, Rhizoma Et Radix Notopterygii 12 parts, Radix Angelicae Pubescentis 12 parts, Radix Gentianae Macrophyllae 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, 15 parts, Poria, Cortex Phellodendri 12 parts, Rhizoma Atractylodis 10 parts, Radix Angelicae Sinensis 15 parts, Ramulus Cinnamomi 8 parts, 15 parts, Rhizoma Gastrodiae, Radix Cynanchi Paniculati 15 parts, Radix Notoginseng 9 parts and 10 parts, Radix Glycyrrhizae.
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104666653A (en) * | 2015-03-04 | 2015-06-03 | 济南骄泰信息技术有限公司 | Traditional Chinese medicine ointment for treating arthritis of knee cap and preparation method of traditional Chinese medicine ointment |
| CN104758412A (en) * | 2015-04-12 | 2015-07-08 | 李锁 | Traditional Chinese medicine composition for treating degenerative gonarthrosis as well as clinic preparation and preparation method of traditional Chinese medicine composition |
| CN104958492A (en) * | 2015-06-26 | 2015-10-07 | 安良云 | Traditional Chinese medicine composition for treating traumatic hemorrhage |
| CN108295113A (en) * | 2018-04-12 | 2018-07-20 | 无锡市中医医院 | A kind of Chinese medicine composition for treating knee osteoarthritis |
| CN110179897A (en) * | 2019-07-08 | 2019-08-30 | 苏州市中医医院 | A kind of formula and preparation method thereof of stilbene rattan soup that treating knee osteoarthritis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1400007A (en) * | 2002-06-10 | 2003-03-05 | 郭好建 | Oral Chinese medicine for curing osteoarthropathy |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1400007A (en) * | 2002-06-10 | 2003-03-05 | 郭好建 | Oral Chinese medicine for curing osteoarthropathy |
Non-Patent Citations (1)
| Title |
|---|
| 中医药治疗膝骨性关节炎的临床研究进展;田志清等;《湖南中医杂志》;20080325;第24卷(第02期);106-108 * |
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