CN104173564A - Traditional Chinese medicine composition for treating rheumatoid arthritis - Google Patents
Traditional Chinese medicine composition for treating rheumatoid arthritis Download PDFInfo
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- CN104173564A CN104173564A CN201410420670.9A CN201410420670A CN104173564A CN 104173564 A CN104173564 A CN 104173564A CN 201410420670 A CN201410420670 A CN 201410420670A CN 104173564 A CN104173564 A CN 104173564A
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Abstract
The invention relates to a traditional Chinese medicine for treating rheumatoid arthritis. The composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-40 parts of astragalus membranaceus, 5-20 parts of radix angelicae pubescentis, 10-40 parts of herba taxilli, 5-20 parts of saposhnicovia divaricata, 2-8 parts of asarum, 10-40 parts of radix aconiti agrestis, 5-20g of gentiana macrophylla, 10-30 parts of radix rehmanniae praeparata, 5-20 parts of ligusticum wallichii, 5-25 parts of radix paeoniae alba, 5-20 parts of angelica sinensis, 5-25 parts of eucommia ulmoides, 5-20 parts of codonopsis pilosula, 5-25 parts of poria cocos, 5-25 parts of radix cyathulae, 5-20 parts of cassia twig, 2-10 parts of pangolin, 5-25 parts of suberect spatholobus stem, 10-40 parts of radix aconiti, 5-20 parts of epimedium, 5-25 parts of nidus vespae, 5-20 parts of scorpion and 5-10 parts of licorice root. The traditional Chinese medicine composition has the effects of strengthening spleen and tonifying kidney, dispelling wind and eliminating dampness, dispersing swelling and relieving pain, clearing heat and dispelling cold, and soothing channels and dredging collaterals, and has the advantages of remarkable curative effect and reliable effect when being used for treating rheumatoid arthritis.
Description
Technical field
The present invention relates to a kind of pharmaceutical product of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of rheumatoid arthritis.
Background technology
Rheumatoid arthritis is a kind of chronic systemic autoimmune disease taking articular synovitis as feature, it is common clinical, frequently-occurring disease, red, swollen, hot with part, bitterly, obtain cold relaxing for principal character, can accompany General Symptoms, heating, the symptoms such as sweating, dry stool, thirsty, red tongue, yellow fur, rapid pulse.Clinical Laboratory shows that erythrocyte sedimentation rate, anti-" O " are higher than normally, the rheumatoid factor positive.Common with female middle-aged.Synovitis is outbreak repeatedly lastingly, the destruction that can cause intraarticular cartilage and bone, and joint function disturbance, even maimed.At present, western medical treatment rheumatoid arthritis, conventional anti-inflammation class medicine, though there is certain curative effect, exists side effect large, and the deficiency that can not effect a radical cure.
Motherland's medical science thinks, rheumatoid arthritis is many is invaded by wind heat damp, and damp and hot friendship resistance is stayed note joint and fallen ill, and does not with the passing of time heal, and causes deficiency of spleen-YANG and kidneyYANG, table Wei Bugu, and susceptible exopathogen causes this disease state of an illness of repeatedly showing effect day by day to increase the weight of.
According to theory of Chinese medical science, for the pathogeny of rheumatoid arthritis, adopt strengthening spleen, tonifying kidney, relax through the method for the treatment of of dredging collateral, expelling wind and removing dampness, dispersing cold for relieving pain, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In prior art, to treat rheumatoid arthritis and have the deficiency that side effect is large, curative effect is undesirable in order to overcome, the invention provides a kind of prepare easy, cost is low, the Chinese medicine composition of evident in efficacy, the treatment rheumatoid arthritis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Astragali 10-40 part, Radix Angelicae Pubescentis 5-20 part, Herba Taxilli 10-40 part, Radix Saposhnikoviae 5-20 part, Herba Asari 2-8 part, Radix Aconiti Kusnezoffii 10-40 part, Radix Gentianae Macrophyllae 5-20 part, Radix Rehmanniae Preparata 10-30 part, Rhizoma Chuanxiong 5-20 part, Radix Paeoniae Alba 5-25 part, Radix Angelicae Sinensis 5-20 part, Cortex Eucommiae 5-25 part, Radix Codonopsis 5-20 part, Poria 5-25 part, Radix Cyathulae 5-25 part, Ramulus Cinnamomi 5-20 part, Squama Manis 2-10 part, Caulis Spatholobi 5-25 part, Radix Aconiti 10-40 part, Herba Epimedii 5-20 part, Nidus Vespae 5-25 part, Scorpio 5-20 part, Radix Glycyrrhizae 5-10 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of rheumatoid arthritis, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 30 parts of the Radixs Astragali, 10 parts of Radix Angelicae Pubescentiss, 30 parts of Herba Taxillis, 10 parts of Radix Saposhnikoviaes, 5 parts of Herba Asaris, 30 parts of Radix Aconiti Kusnezoffii, 10 parts of Radix Gentianae Macrophyllae, 20 parts of Radix Rehmanniae Preparata, 10 parts of Rhizoma Chuanxiongs, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Angelicae Sinensis, 15 parts of the Cortexs Eucommiae, 10 parts of Radix Codonopsis, 15 parts, Poria, 15 parts of Radix Cyathulaes, 10 parts of Ramulus Cinnamomi, 6 parts of Squama Maniss, 15 parts of Caulis Spatholobis, 30 parts of Radix Aconitis, 10 parts of Herba Epimedii, 15 parts, Nidus Vespae, 10 parts of Scorpios, 6 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: the Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling is transported malicious effect; Radix Angelicae Pubescentis has effect of expelling wind and dampness, dispersing cold for relieving pain; Herba Taxilli has effect of invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit; Radix Saposhnikoviae has effect that expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion are jerked surely; Herba Asari has the cold expelling that induces sweat, wind-expelling pain-stopping, warming the lung to resolve fluid-retention, sensible effect; Radix Aconiti Kusnezoffii has effect of expelling wind and removing dampness, antalgic; Radix Gentianae Macrophyllae has effect of Eradicates rheumatism, relaxing muscles and tendons network, clearind deficient heat; Radix Rehmanniae Preparata has effect of the yin nourishing of enriching blood, life essence-filling, marrow-benefitting; Rhizoma Chuanxiong has effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; The Radix Paeoniae Alba has effect of clear and coherent blood vessels, nourishing blood to suppress the hyperactive liver, slow middle arresting sweating; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation; The Cortex Eucommiae has effect of invigorating the liver and kidney, bone and muscle strengthening, invigorating middle warmer benefit vital essence; Radix Codonopsis has effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; Poria has effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Radix Cyathulae has effect of promoting blood circulation to restore menstrual flow, expelling wind and removing dampness, easing joint movement, inducing diuresis for treating stranguria syndrome; Ramulus Cinnamomi has effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; Squama Manis has effect of promoting blood circulation to remove obstruction in the collateral, detumescence and apocenosis, wind-expelling pain-stopping, lactogenesis; Caulis Spatholobi has to enrich blood invigorates blood circulation, relaxes through effect of dredging collateral; Radix Aconiti has effect of expelling wind and removing dampness, antalgic; Herba Epimedii has effect of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; Nidus Vespae has the merit of dispeling the wind poison
,effect of parasite killing pain relieving; Scorpio has effect of endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, helps using mutual assistant, plays altogether strengthening spleen, tonifying kidney, expelling wind and removing dampness, reducing swelling and alleviating pain, heat clearing away cold expelling, relaxes through effect of dredging collateral, and the treatment of rheumatoid arthritis is reached to treating both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, does not occur toxic and side effects, and effective percentage reaches 92%, cure rate 69%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for rheumatoid arthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 30g, Radix Angelicae Pubescentis 10g, Herba Taxilli 30g, Radix Saposhnikoviae 10g, Herba Asari 5g, Radix Aconiti Kusnezoffii 30g, Radix Gentianae Macrophyllae 10g, Radix Rehmanniae Preparata 20g, Rhizoma Chuanxiong 10g, Radix Paeoniae Alba 15g, Radix Angelicae Sinensis 10g, Cortex Eucommiae 15g, Radix Codonopsis 10g, Poria 15g, Radix Cyathulae 15g, Ramulus Cinnamomi 10g, Squama Manis 6g, Caulis Spatholobi 15g, Radix Aconiti 30g, Herba Epimedii 10g, Nidus Vespae 15g, Scorpio 10g, Radix Glycyrrhizae 6g.
Embodiment 2
Treat a Chinese medicine composition for rheumatoid arthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 10g, Radix Angelicae Pubescentis 20g, Herba Taxilli 15g, Radix Saposhnikoviae 5g, Herba Asari 3g, Radix Aconiti Kusnezoffii 40g, Radix Gentianae Macrophyllae 15g, Radix Rehmanniae Preparata 30g, Rhizoma Chuanxiong 5g, Radix Paeoniae Alba 25g, Radix Angelicae Sinensis 12g, Cortex Eucommiae 20g, Radix Codonopsis 5g, Poria 25g, Radix Cyathulae 10g, Ramulus Cinnamomi 20g, Squama Manis 5g, Caulis Spatholobi 25g, Radix Aconiti 10g, Herba Epimedii 20g, Nidus Vespae 5g, Scorpio 15g, Radix Glycyrrhizae 8g.
Embodiment 3
Treat a Chinese medicine composition for rheumatoid arthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 25g, Radix Angelicae Pubescentis 15g, Herba Taxilli 10g, Radix Saposhnikoviae 20g, Herba Asari 6g, Radix Aconiti Kusnezoffii 10g, Radix Gentianae Macrophyllae 20g, Radix Rehmanniae Preparata 10g, Rhizoma Chuanxiong 15g, Radix Paeoniae Alba 10g, Radix Angelicae Sinensis 20g, Cortex Eucommiae 5g, Radix Codonopsis 15g, Poria 10g, Radix Cyathulae 25g, Ramulus Cinnamomi 5g, Squama Manis 8g, Caulis Spatholobi 10g, Radix Aconiti 20g, Herba Epimedii 15g, Nidus Vespae 10g, Scorpio 20g, Radix Glycyrrhizae 5g.
Embodiment 4
Treat a Chinese medicine composition for rheumatoid arthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 20g, Radix Angelicae Pubescentis 12g, Herba Taxilli 25g, Radix Saposhnikoviae 15g, Herba Asari 2g, Radix Aconiti Kusnezoffii 25g, Radix Gentianae Macrophyllae 5g, Radix Rehmanniae Preparata 15g, Rhizoma Chuanxiong 20g, Radix Paeoniae Alba 5g, Radix Angelicae Sinensis 15g, Cortex Eucommiae 10g, Radix Codonopsis 20g, Poria 5g, Radix Cyathulae 20g, Ramulus Cinnamomi 12g, Squama Manis 2g, Caulis Spatholobi 5g, Radix Aconiti 25g, Herba Epimedii 12g, Nidus Vespae 20g, Scorpio 5g, Radix Glycyrrhizae 9g.
Embodiment 5
Treat a Chinese medicine composition for rheumatoid arthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 40g, Radix Angelicae Pubescentis 5g, Herba Taxilli 40g, Radix Saposhnikoviae 12g, Herba Asari 8g, Radix Aconiti Kusnezoffii 35g, Radix Gentianae Macrophyllae 12g, Radix Rehmanniae Preparata 25g, Rhizoma Chuanxiong 12g, Radix Paeoniae Alba 20g, Radix Angelicae Sinensis 5g, Cortex Eucommiae 25g, Radix Codonopsis 12g, Poria 20g, Radix Cyathulae 5g, Ramulus Cinnamomi 15g, Squama Manis 4g, Caulis Spatholobi 20g, Radix Aconiti 40g, Herba Epimedii 5g, Nidus Vespae 25g, Scorpio 12g, Radix Glycyrrhizae 10g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 6 centimetres of powder, decoct for the first time, adopt intense fire to decoct before at a simmer, after boiling with slow fire boiling 20～30 minutes; Decoct for the second time, add water and do not have approximately 4 centimetres of powder, after water boils, decoct 15～20 minutes.Decoct extracting juice twice, merge.
The present invention, with the given a kind of Chinese medicine composition for the treatment of rheumatoid arthritis of embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 100 examples, male 39 examples, female's 61 examples, 40～75 years old age.
Two, diagnostic criteria:
1, Western medicine diagnose standard, with reference to the criteria for classification of 1987 of American Rheumatism Association's revision, possesses 4 persons in following 7:
(1) at least 1h of deadlock in morning, persistent period >=6 week;
(2) 3 or more than 3 swollen joint, persistent period >=6 week;
(3) wrist, the palm refer to, proximal interphalangeal joint is swollen, persistent period >=6 week;
(4) symmetry swollen joint, persistent period >=6 week;
(5) subcutaneous nodule;
(6) the x line of hands and wrist changes (having at least osteoporosis and joint to ask that gap is narrow);
(7) rheumatoid factor (RF) positive.
2, the dialectical diagnostic criteria according to rheumatoid arthritis in " new Chinese medicine guideline of clinical investigations " of tcm syndrome:
(1) primary symptom: arthralgia swelling, local fear of cold, color of the leather is not red, touch not hot, joint joint stuffiness, morning deadlock, joint deformity;
(2) inferior disease: lusterless complexion, limbs fear of cold, clear urine in large amounts, defecates normal or rare half congealed.Pale tongue tongue is white or sliding, deep-slow pulse or heavy weak or heavy tight or heavy sliding slow.
Three, usage and dosage: when clinical practice, potion on the one, the about 400ml of twice extracting juice of decocting, point morning, late twice empty stomach decoction being taken warmly.It within six days, is a course for the treatment of.Avoid cold and uncooked food during the treatment thing of pungent stimulation.
Four, criterion of therapeutical effect: the criterion of therapeutical effect of rheumatoid arthritis in " traditional Chinese medical science disease Standardization of diagnosis and curative effect " issued for 2012 with reference to " new Chinese medicine guideline of clinical investigations " with according to State Administration of Traditional Chinese Medicine:
1, cure: symptom all disappears, it is normal that functional activity recovers, and main doctor trained in Western medicine physico-chemical examination index is normal;
2, effective: symptomatology disappears or cardinal symptom is eliminated, and function of joint is recovered substantially, can participate in normal work or physical labor, physico-chemical examination index normal;
3, effective: cardinal symptom is eliminated substantially, main function of joint is substantially recovered or has made marked progress, and can't take care of oneself and transfers self-care to, or lose the job and work capacity transfers work to and ability to work is recovered to some extent, and mainly physico-chemical examination index makes moderate progress;
4, invalid: and compare before treatment, each side is all without progressive.
Five, therapeutic effect: in this clinical observation case, take medicine 2-6 the course for the treatment of, recovery from illness 69 examples, follow up a case by regular visits to and have no recurrence; Effective 14 examples, effective 9 examples, invalid 8 examples.During treatment, there is not toxic and side effects.
Six, model case:
Case 1: Bian, female, 32 years old.Prolapse sense half a year both feet thumb pain, and follow low grade fever from head to foot, after one week, there is swelling in thumb joint part, pain increases the weight of, and is all affected on foot.Examine and see: lusterless complexion, limbs fear of cold, pale tongue tongue is white, deep and weak pulse.Be diagnosed as: rheumatoid arthritis.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, arthroncus disappears, and pain alleviates; Continue to take 2 courses for the treatment of, all symptoms disappear completely, and it is normal that functional activity recovers.Recovery from illness.After half a year, follow up a case by regular visits to without recurrence.
Case 2: late certain, man, 53 years old.Patient's readme: before 1 year, enlargement, distortion occur for its both hands third finger and little finger of toe joint, and in the recent period, the two hands third fingers and little finger of toe can not carry out flexure operation, and two finger numbnesses occur subcutaneous nodule in its two wrist portion, and brief summary is hard.Be diagnosed as: rheumatoid arthritis.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, two feelings of numbness alleviate, and occur pain; Continue to take 2 courses for the treatment of, subcutaneous nodule disappears, and two finger-joints can basic activity, and pain disappears.
Claims (2)
1. treat the Chinese medicine composition of rheumatoid arthritis for one kind, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Astragali 10-40 part, Radix Angelicae Pubescentis 5-20 part, Herba Taxilli 10-40 part, Radix Saposhnikoviae 5-20 part, Herba Asari 2-8 part, Radix Aconiti Kusnezoffii 10-40 part, Radix Gentianae Macrophyllae 5-20 part, Radix Rehmanniae Preparata 10-30 part, Rhizoma Chuanxiong 5-20 part, Radix Paeoniae Alba 5-25 part, Radix Angelicae Sinensis 5-20 part, Cortex Eucommiae 5-25 part, Radix Codonopsis 5-20 part, Poria 5-25 part, Radix Cyathulae 5-25 part, Ramulus Cinnamomi 5-20 part, Squama Manis 2-10 part, Caulis Spatholobi 5-25 part, Radix Aconiti 10-40 part, Herba Epimedii 5-20 part, Nidus Vespae 5-25 part, Scorpio 5-20 part, Radix Glycyrrhizae 5-10 part.
2. a kind of Chinese medicine composition for the treatment of rheumatoid arthritis according to claim 1, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 30 parts of the Radixs Astragali, 10 parts of Radix Angelicae Pubescentiss, 30 parts of Herba Taxillis, 10 parts of Radix Saposhnikoviaes, 5 parts of Herba Asaris, 30 parts of Radix Aconiti Kusnezoffii, 10 parts of Radix Gentianae Macrophyllae, 20 parts of Radix Rehmanniae Preparata, 10 parts of Rhizoma Chuanxiongs, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Angelicae Sinensis, 15 parts of the Cortexs Eucommiae, 10 parts of Radix Codonopsis, 15 parts, Poria, 15 parts of Radix Cyathulaes, 10 parts of Ramulus Cinnamomi, 6 parts of Squama Maniss, 15 parts of Caulis Spatholobis, 30 parts of Radix Aconitis, 10 parts of Herba Epimedii, 15 parts, Nidus Vespae, 10 parts of Scorpios, 6 parts, Radix Glycyrrhizae.
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| CN105998914A (en) * | 2016-07-15 | 2016-10-12 | 刘源成 | Traditional Chinese medicine composition capable of treating rheumatoid arthritis |
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| CN104758383A (en) * | 2015-03-13 | 2015-07-08 | 陈红旗 | Traditional Chinese medicine composition for treating rheumatism in cold-dampness |
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