CN104825751A - Medicine composition for treating ankylosing spondylitis - Google Patents
Medicine composition for treating ankylosing spondylitis Download PDFInfo
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- CN104825751A CN104825751A CN201510087904.7A CN201510087904A CN104825751A CN 104825751 A CN104825751 A CN 104825751A CN 201510087904 A CN201510087904 A CN 201510087904A CN 104825751 A CN104825751 A CN 104825751A
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Abstract
The invention provides a medicine composition for treating ankylosing spondylitis, wherein the medicine composition consists of, by weight: 12-16 parts of raw astragalus membranaceus, 14-16 parts of radix rehmanniae, 8-12 parts of rhizoma anemarrhenae, 8-12 parts of angelica sinensis, 14-16 parts of caulis sinomenii, 14-16 parts of chinese starjasmine stems, 14-16 parts of solanum nigrum, 14-16 parts of oldenlandia diffusa and 14-16 parts of rhodiola rosea. The medicine composition for treating the ankylosing spondylitis has the effects of boosting qi and nourishing blood, removing toxin and freeing collaterals, strengthening foundation and reinforcing vitality, and eliminating evil and driving away pathological factors. The main drugs, caulis sinomenii and chinese starjasmine stems, have the functions of expelling rheumatism and freeing meridian and collaterals. In the invention, the rattan drugs are used for treating arthralgia syndrome since rattan can enter collaterals and the collaterals can free pulse, so that rattan collaterals can free and active meridian and collaterals and guide the drugs to disease position. The solanum nigrum and the oldenlandia diffusa have the effects of clearing heat, draining dampness and removing toxin. The raw astragalus membranaceus has the effects of boosting qi and tonifying the middle. The rhodiola rosea has the effects of fortifying spleen and boosting qi, and activating blood to resolve stasis. The angelica sinensis has the effects of nourishing and activating blood and strengthen the right and expel the evil. The radix rehmanniae and the rhizoma anemarrhenae have the effects of cooling blood and nourishing yin, can prevent damage on body fluid due to excessive dryness of the medicine, have mainly effects of freeing joints, removing toxin and dispelling stasis with consideration of middle burner regulation, thereby eliminating evil excess without damage on vital qi.
Description
Technical field
The present invention relates to Traditional Chinese medicine composition, be specifically related to a kind of pharmaceutical composition for the treatment of ankylosing spondylitis.
Background technology
Ankylosing spondylitis (ankylosing spondylitis, AS) be a kind of based on Axial sketelon, agnogenic chronic, Progressive symmetric erythrokeratodermia systemic autoimmune disease, belong to rheumatism category, it is generally acknowledged, primary disease occurs relevant with immune-mediated mechanism, gene genetic, infection and environmental factors etc.Within 1973, determine that AS also exists strong association with Human leukocyte antigen-B (HLA-B27).Be that Serology Negative causes modal disease in pain and the stiff SpA of Progressive symmetric erythrokeratodermia, and periarticular and non-bone structural lesions can be comprised.Be called joint accretion spondylitis in some documents abroad, report comparatively is early referred to as poker back, ankylosis spondylitis.Modern medicine not yet works out medicine primary disease being had to definite curative effect.Chinese medicine is thought: AS belongs to the traditional Chinese medical science " arthromyodynia " category, simulataneous insufficiency and excessive, and wind, cold, wet, heat, expectorant become silted up the main pathogenesis of forming for this disease.With Liver and kidney insufficiency of vital energy and blood for this, wind, cold, wet heresy invasion for suffer from, blood stasis expectorant is turbid acts from inside in coordination with forces attacking from outside, pent-up numbness resistance and give birth to " arthromyodynia ".Because of its arthralgia, the touching difficulty of the state of an illness more, has title " rheumatism involving the bone; BI-syndrome involved the kidney ", many medical scholars, through a large amount of clinical researches, define determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, treatment by stages, special side's treatment, Chinese Traditional Medicines and various external treatment, wherein pattern of syndrome most study, curative effect is more definite, but be difficult to be formed and quantize unification, the Therapeutic Method of clear curative effect.
Summary of the invention
The object of this invention is to provide a kind of pharmaceutical composition for the treatment of ankylosing spondylitis, said composition has benefiting QI and nourishing blood, effect of dispelling toxins and dredging collaterals, reinforcing primordial QI reinforcing, eliminating evil go out (giving consideration to both the incidental and fundamental), principal agent Caulis Sinomenii, Caulis Trachelospermi wind-damp dispelling, the meridian dredging, select rattan class Drug therapy arthromyodynia, because rattan can enter network, network can be promoted blood circulation, and rattan network can qualcomm meridian, active arteries and veins, and draw all medicines and to go directly disease institute; Herba Solani Nigri, the removing toxic substances of Herba Hedyotidis Diffusae clearing away heat-damp and promoting diuresis; The invigorating middle warmer of Radix Astragali QI invigorating; Radix Rhodiolae invigorating the spleen and benefiting QI, blood circulation promoting and blood stasis dispelling; Chinese Angelica blood replonishing is invigorated blood circulation, strengthening vital QI to eliminate pathogenic factors; The Radix Rehmanniae, Rhizoma Anemarrhenae removing heat from blood YIN nourishing, again can the too dry impairment of body fluid liquid of opopanax, based on easing joint movement, detoxification and removing stasis, takes into account in mediation burnt, can be eliminating evil real and do not hinder healthy energy.
To achieve the above object of the invention, the technical solution used in the present invention is: a kind of pharmaceutical composition for the treatment of ankylosing spondylitis, is made up of the raw material of following weight portion:
Radix Astragali 12 ~ 16 parts,
14 ~ 16 parts, the Radix Rehmanniae,
The Rhizoma Anemarrhenae 8 ~ 12 parts,
Radix Angelicae Sinensis 8 ~ 15 parts,
Caulis Sinomenii 14 ~ 18 parts,
Caulis Trachelospermi 14 ~ 18 parts,
Herba Solani Nigri 14 ~ 18 parts,
Herba Hedyotidis Diffusae 14 ~ 18 parts,
Radix Rhodiolae 14 ~ 20 parts.
The technical scheme improved further in technique scheme is as follows:
1., in such scheme, be made up of the raw material of following parts by weight:
Radix Astragali 12 ~ 16 parts,
14 ~ 16 parts, the Radix Rehmanniae,
The Rhizoma Anemarrhenae 8 ~ 12 parts,
Radix Angelicae Sinensis 8 ~ 12 parts,
Caulis Sinomenii 16 ~ 18 parts,
Caulis Trachelospermi 16 ~ 18 parts,
Herba Solani Nigri 16 ~ 18 parts,
Herba Hedyotidis Diffusae 16 ~ 18 parts,
Radix Rhodiolae 14 ~ 16 parts.
2., in such scheme, be made up of the raw material of following parts by weight:
Radix Astragali 16 ~ 20 parts,
16 ~ 18 parts, the Radix Rehmanniae,
The Rhizoma Anemarrhenae 8 ~ 12 parts,
Radix Angelicae Sinensis 12 ~ 15 parts,
Caulis Sinomenii 14 ~ 16 parts,
Caulis Trachelospermi 14 ~ 16 parts,
Herba Solani Nigri 14 ~ 16 parts,
Herba Hedyotidis Diffusae 14 ~ 16 parts,
Radix Rhodiolae 16 ~ 20 parts.
Due to the utilization of technique scheme, the present invention compared with prior art has following advantages:
1. the present invention treats the pharmaceutical composition of ankylosing spondylitis, inheriting Wumen doctor sends on the basis of Conventional wisdom, professor Gong Zhengfeng is in conjunction with oneself clinical experience for many years, the opinion of its uniqueness is had in treatment ankylosing spondylitis, ankylosing spondylitis i.e. interior " severe hunch-back " through thinking is proposed, to its morbidity because of, mainly from thinking that natural endowment is not enough, acquired environment affects, emotional stimulation, cause caused by liver and kidney deficiency, asthenia of essence and blood, governor vessel loses supports, and the exopathogen such as rheumatic fever are taken advantage of a weak point in opponent's defence and attacked, go deep into skeleton, stay and form primary disease in spinal column; Liver and kidney blood and essence asthenia, makes clonic spasm of the muscle weak bone and heresy stay and does not go, gradually raw phlegm-turbidity and blood stasis blood, and cementing and touching difficulty more mutually.Its character is deficiency in origin and excess in superficiality, and Liver and kidney, governor vessel are deficient is this, and rheumatic fever and phlegm-turbidity and blood stasis blood are mark, and Radix Astragali in compositions, the Radix Rehmanniae, Radix Angelicae Sinensis, Radix Rhodiolae are the product of liver and kidney tonifying, nourishing blood and replenishing essence; Caulis Sinomenii, Caulis Trachelospermi, Herba Solani Nigri, Herba Hedyotidis Diffusae are the product of wind-damp dispelling, heat-clearing and toxic substances removing, easing joint movement; The Radix Rehmanniae, the Rhizoma Anemarrhenae are the anti-medicine too dry impairment of body fluid liquid that dispels the wind, and with removing heat from blood Yin-nourishing and body fluid promoting, giving consideration to both the incidental and fundamental like this, reinforcing primordial QI reinforcing, eliminating evilly goes out.
2. the present invention treats the pharmaceutical composition of ankylosing spondylitis, Gong Zhengfeng professor is divided into active stage and catabasis two stage medications ankylosing spondylitis, active stage, pathogenesis was based on damp and hot retardance, increase the weight of Caulis Sinomenii, Caulis Trachelospermi, Herba Solani Nigri, Herba Hedyotidis Diffusae consumption based on clearing away heat-damp and promoting diuresis; Catabasis pathogenesis loses support based on deficiency of the liver and kindey, governor vessel, increase the weight of Radix Astragali, the Radix Rehmanniae, Radix Angelicae Sinensis, Radix Rhodiolae consumption based on invigorating the liver and kidney, fill governor vessel, bone and muscle strengthening, it can be held letter and drive numerous, get twice the result with half the effort, need take medicine over a long time because patient is many, therefore gentle method should be selected, resolutely oppose the effect for scheming a period of time, and absurd under search wind and walk to alter heavy prescription, hinder healthy energy on foot, cause pathogen and go deep into internal organs in an opponent's defence.Rash medication is done people great harm, and should abide by the purport of YE Tian shi " chronic disease should delay attack ".
Detailed description of the invention
Embodiment 1: a kind of pharmaceutical composition for the treatment of ankylosing spondylitis, is made up of the raw material of following weight portion:
Radix Astragali 15 parts,
15 parts, the Radix Rehmanniae,
The Rhizoma Anemarrhenae 10 parts,
Radix Angelicae Sinensis 10 parts,
Caulis Sinomenii 15 parts,
Caulis Trachelospermi 15 parts,
Herba Solani Nigri 15 parts,
Herba Hedyotidis Diffusae 15 parts,
Radix Rhodiolae 15 parts.
Be decocted in water for oral dose every day 1 dose, point 2 clothes.Surrounding is a course for the treatment of.
Embodiment 2: a kind of pharmaceutical composition for the treatment of ankylosing spondylitis, is made up of the raw material of following weight portion:
Radix Astragali 14 parts,
15 parts, the Radix Rehmanniae,
The Rhizoma Anemarrhenae 9 parts,
Radix Angelicae Sinensis 10 parts,
Caulis Sinomenii 18 parts,
Caulis Trachelospermi 18 parts,
Herba Solani Nigri 17 parts,
Herba Hedyotidis Diffusae 18 parts,
Radix Rhodiolae 14 parts.
Be decocted in water for oral dose every day 1 dose, point 2 clothes.Surrounding is a course for the treatment of.
Embodiment 3: a kind of pharmaceutical composition for the treatment of ankylosing spondylitis, is made up of the raw material of following weight portion:
Radix Astragali 15 parts,
15 parts, the Radix Rehmanniae,
The Rhizoma Anemarrhenae 10 parts,
Radix Angelicae Sinensis 8 parts,
Caulis Sinomenii 15 parts,
Caulis Trachelospermi 15 parts,
Herba Solani Nigri 14 parts,
Herba Hedyotidis Diffusae 15 parts,
Radix Rhodiolae 16 parts.
Be decocted in water for oral dose every day 1 dose, point 2 clothes.Surrounding is a course for the treatment of.
Embodiment 4: a kind of pharmaceutical composition for the treatment of ankylosing spondylitis, is made up of the raw material of following weight portion:
Radix Astragali 18 parts,
18 parts, the Radix Rehmanniae,
The Rhizoma Anemarrhenae 8 ~ 12 parts,
Radix Angelicae Sinensis 14 parts,
Caulis Sinomenii 14 ~ 16 parts,
Caulis Trachelospermi 14 ~ 16 parts,
Herba Solani Nigri 14 ~ 16 parts,
Herba Hedyotidis Diffusae 14 ~ 16 parts,
Radix Rhodiolae 18 parts.
Be decocted in water for oral dose every day 1 dose, point 2 clothes.Surrounding is a course for the treatment of.
Clinical practice example: example one: Zhao, man, 35 years old.Ankylosing spondylitis more than 5 years.Lumbar vertebrae pain recurrent exerbation, movable unfavorable, companion is stiff for morning, stomach receive can, red urine, stool is adjusted, yellow fur, thready and rapid pulse.Health check-up: lumbar vertebra range of activity is anteflexion 60 °, after stretch 10 °, bilateral sacroiliac joint kowtows pain obviously, x-ray shows: lumbar vertebra physiologic radian straightens, joint of lumbar vertebra ligament without obvious ossified sign, bilateral sacroiliac joint hypertrophy, gap turn narrow, immunologic test HLA-B27(+), erythrocyte sedimentation rate 30mm/1h.The rule for the treatment of: heat-clearing and toxic substances removing, dispelling wind and removing obstruction in the collateral.Take the Chinese medicine composition of this kind of took orally for treating ankylosing spondylitis, after the course for the treatment of, lumbago symptom alleviates, and morning, deadlock also took a turn for the better, after after treatment two the transference cure course for the treatment of again, activity is freely.
Example two: Lee, man, 27 years old.Suffer from ankylosing spondylitis 1 year, waist and sacrum pain, stiff, be very with WA in morning especially, continue about 1 hour, once took western medicine in Duo Jia hospital, poor effect, gastral cavilty portion feeling of distension and oppression discomfort, anorexia.Auxiliary examination: HLA-B27(+), erythrocyte sedimentation rate 61mm/1h, c reactive protein 31.X-ray shows: bilateral sacroiliac joint gap turn narrow, fuzzy.Take the Chinese medicine composition of this kind of took orally for treating ankylosing spondylitis, two the course for the treatment of low back sacrum pain symptom alleviate, morning, deadlock also took a turn for the better, after after treatment three the transference cure course for the treatment of again.
Example three: Wang, man, 30 years old.Suffer from ankylosing spondylitis 3 years, the stiff pain of lumbar vertebra, sacroiliac joint, the stiff pain in neck portion, rotate difficulty, morning is stiff, takes Chinese medicine and western medicine poor effect.Auxiliary examination: HLA-B27(+), erythrocyte sedimentation rate 61mm/1h, c reactive protein 31.X-ray shows: bilateral sacroiliac joint gap turn narrow, fuzzy.MRI: bilateral sacroiliac joint signal increases hydrops.Take the Chinese medicine composition of this kind of took orally for treating ankylosing spondylitis, after two courses for the treatment of, many symptoms alleviate, and morning, deadlock also took a turn for the better, after after treatment four the transference cure course for the treatment of again.
Example four: Zhang, female, 21 years old.Suffer from ankylosing spondylitis 4 years, bilateral sacroiliac joint, the hip arthralgia, stiff, movable difficulty, walks unfavorable.Once hormone therapy was used, patient's central obesity, epidermatic atrophy.Auxiliary examination: HLA-B27(+), erythrocyte sedimentation rate 32mm/1h, c reactive protein 25.X-ray shows: bilateral sacroiliac joint gap turn narrow, hip joint shows no obvious abnormalities.MRI: bilateral sacroiliac joint, hip joint signal increase hydrops.Take the Chinese medicine composition of this kind of took orally for treating ankylosing spondylitis, after two courses for the treatment of, sacroiliac joint, hip arthralgia symptom alleviate, and stiffly also take a turn for the better, after after treatment 6 the transference cure course for the treatment of again.
Take the traditional Chinese medicine composition for treating ankylosing spondylitis acceptance rate that this kind treat ankylosing spondylitis and reach more than 95%, divide active stage and catabasis treatment clinically, relapse rate is very low.
Above-described embodiment, only for technical conceive of the present invention and feature are described, its object is to person skilled in the art can be understood content of the present invention and implement according to this, can not limit the scope of the invention with this.All equivalences done according to spirit of the present invention change or modify, and all should be encompassed within protection scope of the present invention.
Claims (3)
1. treat a pharmaceutical composition for ankylosing spondylitis, it is characterized in that: be made up of the raw material of following parts by weight:
Radix Astragali 12 ~ 16 parts,
14 ~ 16 parts, the Radix Rehmanniae,
The Rhizoma Anemarrhenae 8 ~ 12 parts,
Radix Angelicae Sinensis 8 ~ 15 parts,
Caulis Sinomenii 14 ~ 18 parts,
Caulis Trachelospermi 14 ~ 18 parts,
Herba Solani Nigri 14 ~ 18 parts,
Herba Hedyotidis Diffusae 14 ~ 18 parts,
Radix Rhodiolae 14 ~ 20 parts.
2. the pharmaceutical composition for the treatment of ankylosing spondylitis according to claim 1, is characterized in that: be made up of the raw material of following parts by weight:
Radix Astragali 12 ~ 16 parts,
14 ~ 16 parts, the Radix Rehmanniae,
The Rhizoma Anemarrhenae 8 ~ 12 parts,
Radix Angelicae Sinensis 8 ~ 12 parts,
Caulis Sinomenii 16 ~ 18 parts,
Caulis Trachelospermi 16 ~ 18 parts,
Herba Solani Nigri 16 ~ 18 parts,
Herba Hedyotidis Diffusae 16 ~ 18 parts,
Radix Rhodiolae 14 ~ 16 parts.
3. the pharmaceutical composition for the treatment of ankylosing spondylitis according to claim 1, is characterized in that: be made up of the raw material of following parts by weight:
Radix Astragali 16 ~ 20 parts,
16 ~ 18 parts, the Radix Rehmanniae,
The Rhizoma Anemarrhenae 8 ~ 12 parts,
Radix Angelicae Sinensis 12 ~ 15 parts,
Caulis Sinomenii 14 ~ 16 parts,
Caulis Trachelospermi 14 ~ 16 parts,
Herba Solani Nigri 14 ~ 16 parts,
Herba Hedyotidis Diffusae 14 ~ 16 parts,
Radix Rhodiolae 16 ~ 20 parts.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102846915A (en) * | 2012-09-28 | 2013-01-02 | 郑州中医骨伤病医院 | Yin-nourishing and kidney-tonifying pill for treating ankylosing spondylitis |
| CN103191383A (en) * | 2013-03-14 | 2013-07-10 | 黄相杰 | Traditional Chinese medicine composition for treating rheumatoid arthritis |
| CN103705894A (en) * | 2013-12-24 | 2014-04-09 | 李媛春 | Traditional Chinese medicine decoction for treating rheumatoid arthritis |
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- 2015-02-26 CN CN201510087904.7A patent/CN104825751A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102846915A (en) * | 2012-09-28 | 2013-01-02 | 郑州中医骨伤病医院 | Yin-nourishing and kidney-tonifying pill for treating ankylosing spondylitis |
| CN103191383A (en) * | 2013-03-14 | 2013-07-10 | 黄相杰 | Traditional Chinese medicine composition for treating rheumatoid arthritis |
| CN103705894A (en) * | 2013-12-24 | 2014-04-09 | 李媛春 | Traditional Chinese medicine decoction for treating rheumatoid arthritis |
Non-Patent Citations (1)
| Title |
|---|
| 陈欣 等: ""龚正丰防治强脊经验"", 《中国中医药报2013年12月6日第004版》 * |
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Application publication date: 20150812 |